CN216236963U - Nucleic acid extraction plate with sealing film - Google Patents

Nucleic acid extraction plate with sealing film Download PDF

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Publication number
CN216236963U
CN216236963U CN202122896844.7U CN202122896844U CN216236963U CN 216236963 U CN216236963 U CN 216236963U CN 202122896844 U CN202122896844 U CN 202122896844U CN 216236963 U CN216236963 U CN 216236963U
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sealing film
magnetic
plate
extraction plate
nucleic acid
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CN202122896844.7U
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王慧敏
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Shijiazhuang Huipu Biotechnology Co ltd
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Shijiazhuang Huipu Biotechnology Co ltd
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Abstract

The utility model provides a nucleic acid extraction plate with a sealing film, and relates to the technical field of nucleic acid extraction. The nucleic acid extraction plate with the sealing film comprises: the upper surface of the extraction plate main body is provided with a plurality of rows of uniformly distributed sample adding holes; the number of the magnetic rings is multiple, the magnetic rings are all embedded on the upper surface of the extraction plate main body, and each magnetic ring is arranged around the corresponding row of the sample adding holes; the number of the magnetic cover plate mechanisms is multiple, and the magnetic cover plate mechanisms are all rotatably connected with the extraction plate main body; the magnetic cover plate mechanism is matched with the corresponding magnetic ring; the sealing film storage mechanism is connected with the extraction plate main body. The nucleic acid extraction plate with the sealing film has the advantage of reducing the breakage probability of the sealing film.

Description

Nucleic acid extraction plate with sealing film
Technical Field
The utility model relates to the technical field of nucleic acid extraction, in particular to a nucleic acid extraction plate with a sealing film.
Background
The principle of nucleic acid extraction firstly guarantees the integrity of the primary structure of the nucleic acid, and secondly excludes contamination by other molecules. In the process of nucleic acid extraction, a pre-packaged 96-well nucleic acid extraction plate is required, and after nucleic acid extraction is completed, the sample application holes of the nucleic acid extraction plate are generally shielded by a sealing film in order to reduce contamination of samples in the sample application holes.
However, in the process of implementing the technical solution in the embodiments of the present application, the inventors of the present application have found that the above-mentioned technology has at least the following technical problems;
because the sealing film is thin and batch operation is required to be carried out on the same nucleic acid extraction plate, the sealing film is easy to be touched by mistake in subsequent operation, and the probability of accidental breakage of the sealing film is increased.
Therefore, it is necessary to provide a new nucleic acid extraction plate with a sealing film to solve the above-mentioned problems.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problems, the utility model provides a nucleic acid extraction plate with a sealing film, which reduces the accidental breakage of the sealing film.
The utility model provides a nucleic acid extraction plate with a sealing film, which comprises: the upper surface of the extraction plate main body is provided with a plurality of rows of uniformly distributed sample adding holes; the number of the magnetic rings is multiple, the magnetic rings are all embedded on the upper surface of the extraction plate main body, and each magnetic ring is arranged around the corresponding row of the sample adding holes; the magnetic cover plate mechanisms are multiple in number and are all rotatably connected with the extraction plate main body; the magnetic cover plate mechanism is matched with the corresponding magnetic ring; the sealing film storage mechanism is connected with the extraction plate main body.
Preferably, the magnetic cover plate mechanism comprises a fixed block, the side surface of the extraction plate main body is fixedly connected with the fixed block, the fixed block is rotatably connected with one end of an L-shaped connecting plate through a rotating shaft, and the other end of the L-shaped connecting plate is fixedly connected with a magnetic fixed frame which is provided with an upper opening and a lower opening and is matched with the magnetic ring; the opening at the upper end of the magnetic fixing frame is fixedly connected with a top cover, and the magnetism of the magnetic fixing frame is opposite to that of the opposite end of the magnetic ring.
The sealing film can be extruded through the magnetic fixing frame and the magnetic ring, so that the sample adding hole can be separated from the external environment through the sealing film, the probability of sample pollution in the sample adding hole is avoided, and meanwhile, the nucleic acid extract in the sample adding hole does not need to be separately sucked out and stored; the sealing film can be shielded through the magnetic fixing frame and the top cover, and the probability of contact between the sealing film and an external object is reduced, so that the probability of accidental damage of the sealing film is reduced, and the use reliability of the device is improved.
Preferably, the magnetic cover plate mechanism further comprises side lugs, and one end, far away from the L-shaped connecting plate, of the magnetic fixing frame is fixedly connected with the side lugs.
The magnetic fixing frame is convenient for operators to pull through the side lugs, and the use of the device is facilitated.
Preferably, the lower surface of the magnetic fixing frame is fixedly connected with a silica gel pad, and the upper surface of the magnetic ring is also fixedly connected with the silica gel pad;
the magnetic fixing frame can be in soft contact with the corresponding magnetic ring through the silica gel pad, so that the sealing film can be better extruded and sealed, and the sealing effect on the sampling hole is further ensured;
meanwhile, the silica gel pad is soft, so that the damage probability of the sealing film is reduced.
Preferably, sealing film storage mechanism includes the wind-up roll, and the mounting groove has been seted up to the one end of drawing the board main part, and the mounting groove internal rotation is connected with the wind-up roll, and the winding has the sealing film that is used for sealing the application of sample hole on the wind-up roll.
The sealing film is placed on the winding roller and can be torn off from the winding roller by pulling the sealing film, so that the sampling hole can be shielded and sealed.
Preferably, the sealing film storage mechanism further comprises a movable plate, the movable plate is connected in the mounting groove in a sliding mode, and the surface, opposite to the winding roller, of the movable plate is rotatably connected with a limiting cover; one end of the winding roller is inserted into the limiting cover, and the other end of the winding roller is rotatably connected into a positioning groove formed in the inner wall of the mounting groove; the surfaces of the movable plate, which are back to the winding roller, are elastically connected with the inner wall of the mounting groove through springs.
Elastic deformation can take place for the spring through the pulling fly leaf to make the wind-up roll can follow the roll-off in the spacing cover, thereby take off the wind-up roll, be favorable to the change of sealing film on wind-up roll and the wind-up roll, be favorable to the use of device.
Preferably, a serrated plate is fixedly connected in the mounting groove, and the upper surface of the serrated plate is serrated.
The serrated plate is favorable for cutting off the sealing film, and the use difficulty of the device is reduced.
Preferably, the edge of the lower surface of the extraction plate main body is fixedly connected with supporting legs, and the lower surfaces of the supporting legs are fixedly connected with rubber pads.
The friction force between the desktop can be increased and placed through the supporting legs and the rubber pads, and therefore the placing stability of the device is improved.
Preferably, the top cover is made of transparent materials, and the top cover has a writing function.
The use states of the sample adding hole and the sealing film can be conveniently observed through the transparent top cover, and the use of the device is facilitated.
Preferably, the corners of the extracting plate main body are provided with round corners.
Make the corner of drawing the board main part more mellow and more through the fillet, reduce operating personnel and be drawn the unexpected fish tail probability of corner of board main part, improve the security that the device used.
Compared with the related art, the nucleic acid extraction plate with the sealing film has the following beneficial effects:
1. the sealing film can be extruded through the magnetic fixing frame and the magnetic ring, so that the sample adding hole can be separated from the external environment through the sealing film, the probability of sample pollution in the sample adding hole is avoided, and meanwhile, the nucleic acid extract in the sample adding hole does not need to be separately sucked out and stored;
2. according to the utility model, the sealing film can be shielded through the magnetic fixing frame and the top cover, so that the probability of the sealing film contacting with an external object is reduced, the probability of accidental damage of the sealing film is reduced, and the use reliability of the device is improved;
3. when the sealing film taking device is used, the magnetic fixing frame and the corresponding magnetic ring are attracted by magnetic force, so that the sealing film is convenient to take, and when the magnetic fixing frame is pulled by external force, the sealing film can be completely taken down, so that the problem of sealing film residue is avoided, and the use of the sealing film taking device is facilitated.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic structural view of a preferred embodiment of a nucleic acid extraction plate with a sealing film according to the present invention;
FIG. 2 is a schematic side view of the nucleic acid isolation plate with a sealing film of FIG. 1;
FIG. 3 is a schematic structural view of the magnetic cover mechanism shown in FIG. 2;
fig. 4 is a schematic structural view of the sealing film storing mechanism shown in fig. 2.
Reference numbers in the figures: 1. a magnetic cover plate mechanism; 11. a top cover; 12. an L-shaped connecting plate; 13. a lateral ear; 14. a magnetic fixing frame; 15. a fixed block; 2. an extraction plate main body; 3. a sample application hole; 4. supporting legs; 5. a sealing film storage mechanism; 51. a movable plate; 52. a spring; 53. a limiting cover; 54. a wind-up roll; 6. a serrated plate; 7. a magnetic ring.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the embodiments of the present invention, it should be noted that, if the terms "upper", "lower", "vertical", "horizontal", "inner", etc. are used for indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings or the orientation or positional relationship which is usually placed when the products of the present invention are used, the description is only for convenience and simplicity, but the indication or suggestion that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
In the description of the embodiments of the present invention, "plurality" if any, means at least 2.
In the description of the embodiments of the present invention, it should be further noted that unless otherwise explicitly stated or limited, the terms "disposed," "mounted," and "connected" should be interpreted broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Examples
Referring to fig. 1 to 4, a nucleic acid extracting plate with a sealing film includes:
the upper surface of the extraction plate main body 2 is provided with a plurality of rows of sample adding holes 3 which are uniformly distributed;
the number of the magnetic rings 7 is multiple, the magnetic rings 7 are all embedded on the upper surface of the extraction plate main body 2, and each magnetic ring 7 is arranged around the corresponding row of the sample adding holes 3;
the number of the magnetic cover plate mechanisms 1 is multiple, and the magnetic cover plate mechanisms 1 are all rotatably connected with the extraction plate main body 2;
the magnetic cover plate mechanism 1 is matched with the corresponding magnetic ring 7;
and the sealing film storage mechanism 5 is connected with the extraction plate main body 2.
Need to explain: when the device is used, after a sample is added into the sample adding hole 3, the sample adding hole 3 can be shielded by taking off the sealing film on the sealing film storage mechanism 5, and the sealing film can be extruded through the magnetic force cooperation of the magnetic cover plate mechanism 1 and the corresponding magnetic ring 7, so that the sample adding hole 3 is separated from the external environment through the sealing film, the probability of pollution of the sample in the sample adding hole 3 is avoided, and meanwhile, the nucleic acid extract in the sample adding hole does not need to be separately sucked out for additional storage;
it is also stated that: the sealing film can be shielded through the magnetic cover plate mechanism 1, and the probability of contact between the sealing film and an external object is reduced, so that the probability of accidental damage of the sealing film is reduced, and the use reliability of the device is improved;
it is also stated that: the magnetic cover plate mechanism 1 and the corresponding magnetic ring 7 are magnetically adsorbed, so that the sealing film is convenient to take, the problem of sealing film residue is avoided, and the device is favorable for use.
Referring to fig. 1, 2 and 3, the magnetic cover plate mechanism 1 includes a fixing block 15, the side surface of the extraction plate main body 2 is fixedly connected with the fixing block 15, the fixing block 15 is rotatably connected with one end of an L-shaped connecting plate 12 through a rotating shaft, and the other end of the L-shaped connecting plate 12 is fixedly connected with a magnetic fixing frame 14 which is opened up and down and matched with the magnetic ring 7;
a top cover 11 is fixedly connected to an opening at the upper end of the magnetic fixing frame 14, and the magnetism of the magnetic fixing frame 14 is opposite to that of the opposite end of the magnetic ring 7.
Need to explain: after the sealing film on the sealing film storage mechanism 5 is taken down to shield the sample adding hole 3, the magnetic fixing frame 14 is rotated to enable the magnetic fixing frame 14 and the magnetic ring 7 to be in contact with each other and attract each other, the sealing film can be extruded through the magnetic fixing frame 14 and the magnetic ring 7, so that the sample adding hole 3 can be separated from the external environment through the sealing film, the probability of pollution of a sample in the sample adding hole 3 is avoided, and meanwhile, the nucleic acid extract in the sample adding hole does not need to be separately sucked out and stored;
it is also stated that: the sealing film can be shielded through the magnetic fixing frame 14 and the top cover 11, so that the probability of contact between the sealing film and an external object is reduced, the probability of accidental damage of the sealing film is reduced, and the use reliability of the device is improved;
it is also stated that: the magnetic fixing frame 14 and the corresponding magnetic ring 7 are attracted by magnetic force, so that the sealing film is convenient to take, and when the magnetic fixing frame 14 is pulled by external force, the sealing film can be completely taken down, so that the problem of sealing film residue is avoided, and the device is favorable for use.
Referring to fig. 3, the magnetic cover plate mechanism 1 further includes side lugs 13, and the end of the magnetic fixing frame 14 far away from the L-shaped connecting plate 12 is fixedly connected with the side lugs 13.
Need to explain: the magnetic fixing frame 14 is convenient for an operator to pull through the side ears 13, and the device is convenient to use.
Referring to fig. 3, a silicone pad is fixedly connected to the lower surface of the magnetic fixing frame 14, and a silicone pad is also fixedly connected to the upper surface of the magnetic ring 7.
Need to explain: the magnetic fixing frame 14 can be in soft contact with the corresponding magnetic ring 7 through the silica gel pad, so that the sealing film can be better extruded and sealed, and the sealing effect on the sample adding hole 3 is further ensured;
meanwhile, the silica gel pad is soft, so that the damage probability of the sealing film is reduced.
Referring to fig. 2 and 4, the sealing film storage mechanism 5 includes a winding roller 54, an installation groove is formed in one end of the extraction plate main body 2, the winding roller 54 is rotatably connected to the installation groove, and a sealing film for sealing the sampling hole 3 is wound on the winding roller 54.
Need to explain: the sealing film is placed on the winding roller 54, and can be torn off from the winding roller 54 by pulling the sealing film, so that the sampling hole 3 can be shielded and sealed.
Referring to fig. 1, the sealing film storage mechanism 5 further includes a movable plate 51, the movable plate 51 is slidably connected in the mounting groove, and a limiting cover 53 is rotatably connected to a surface of the movable plate 51 opposite to the wind-up roll 54;
one end of the winding roller 54 is inserted into the limiting cover 53, and the other end of the winding roller 54 is rotatably connected into a positioning groove formed in the inner wall of the mounting groove;
the surface of the movable plate 51 opposite to the winding roller 54 is elastically connected with the inner wall of the mounting groove through a spring 52.
Need to explain: the spring 52 can be elastically deformed by pulling the movable plate 51, so that the winding roller 54 can slide out of the limiting cover 53, the winding roller 54 is taken down, the winding roller 54 and the sealing film on the winding roller 54 are replaced, and the device is used.
It is also stated that: the inner wall of the mounting groove is provided with a strip-shaped chute for limiting the movable plate 51.
Referring to fig. 1, a serrated plate 6 is fixedly connected in the mounting groove, and the upper surface of the serrated plate 6 is serrated.
Need to explain: the serrated plate 6 is beneficial to cutting off the sealing film, and the use difficulty of the device is reduced.
Referring to fig. 1, the lower surface of the extraction plate body 2 is fixedly connected with supporting legs 4 at the corners, and the lower surface of the supporting legs 4 is fixedly connected with a rubber pad.
Need to explain: the friction force between the desktop and the placing table can be increased through the supporting legs 4 and the rubber pads, and therefore the placing stability of the device is improved.
Referring to fig. 1, the top cover 11 is made of transparent material, and the top cover 11 has a writing function.
Need to explain: the use states of the sampling holes 3 and the sealing film can be conveniently observed through the transparent top cover 11, the use of the device is facilitated, and the marks can be written on the top cover 11, so that the marking of the sampling holes in different rows is facilitated.
Referring to fig. 1, the corners of the extracting plate body 2 are rounded.
Need to explain: make the corner of drawing board main part 2 more mellow and more through the fillet, reduce the probability that operating personnel is drawn the unexpected fish tail of corner of board main part 2, improve the security that the device used.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A nucleic acid extraction plate with a sealing film, comprising:
the upper surface of the extraction plate main body (2) is provided with a plurality of rows of uniformly distributed sample adding holes (3);
the number of the magnetic rings (7) is multiple, the magnetic rings (7) are all embedded on the upper surface of the extraction plate main body (2), and each magnetic ring (7) is arranged around the corresponding row of the sample adding holes (3);
the number of the magnetic cover plate mechanisms (1) is multiple, and the magnetic cover plate mechanisms (1) are rotatably connected with the extraction plate main body (2); the magnetic cover plate mechanism (1) is matched with the corresponding magnetic ring (7);
the sealing film storage mechanism (5) is connected with the extraction plate main body (2).
2. The nucleic acid extraction plate with the sealing film as claimed in claim 1, wherein the magnetic cover plate mechanism (1) comprises a fixed block (15), the fixed block (15) is fixedly connected to the side surface of the extraction plate body (2), the fixed block (15) is rotatably connected to one end of an L-shaped connecting plate (12) through a rotating shaft, and the other end of the L-shaped connecting plate (12) is fixedly connected to a magnetic fixed frame (14) which is provided with an upper opening and a lower opening and is matched with the magnetic ring (7); the opening at the upper end of the magnetic fixing frame (14) is fixedly connected with a top cover (11), and the magnetism of the opposite end of the magnetic fixing frame (14) and the magnetism of the opposite end of the magnetic ring (7) are opposite.
3. The nucleic acid extraction plate with sealing film as claimed in claim 2, wherein the magnetic cover plate mechanism (1) further comprises a side lug (13), and the end of the magnetic fixing frame (14) far away from the L-shaped connecting plate (12) is fixedly connected with the side lug (13).
4. The nucleic acid extraction plate with sealing film as claimed in claim 3, wherein a silica gel pad is fixedly connected to the lower surface of the magnetic fixing frame (14), and a silica gel pad is also fixedly connected to the upper surface of the magnetic ring (7).
5. The nucleic acid extraction plate with the sealing film as claimed in any one of claims 1 to 4, wherein the sealing film storage mechanism (5) comprises a winding roller (54), one end of the extraction plate main body (2) is provided with an installation groove, the winding roller (54) is rotatably connected in the installation groove, and the winding roller (54) is wound with the sealing film for sealing the sampling hole (3).
6. The nucleic acid extraction plate with the sealing film as claimed in claim 5, wherein the sealing film storage mechanism (5) further comprises a movable plate (51), the movable plate (51) is connected in the mounting groove in a sliding manner, and a limiting cover (53) is rotatably connected to the surface of the movable plate (51) opposite to the wind-up roll (54); one end of the winding roller (54) is inserted into the limiting cover (53), and the other end of the winding roller (54) is rotatably connected into a positioning groove formed in the inner wall of the mounting groove; the surface of the movable plate (51) opposite to the winding roller (54) is elastically connected with the inner wall of the mounting groove through a spring (52).
7. The nucleic acid extraction plate with sealing film as claimed in claim 5, wherein a serrated plate (6) is fixedly connected in the mounting groove, and the upper surface of the serrated plate (6) is serrated.
8. The nucleic acid extraction plate with sealing film as claimed in claim 1, wherein the lower surface of the extraction plate body (2) is fixedly connected with support legs (4) at the corners, and the lower surface of the support legs (4) is fixedly connected with rubber pads.
9. The nucleic acid extraction plate with sealing film according to claim 2, wherein the top cover (11) is made of transparent material, and the top cover (11) has a writing function.
10. The nucleic acid extraction plate with sealing film as claimed in any one of claims 1 to 4, wherein the corners of the extraction plate body (2) are rounded.
CN202122896844.7U 2021-11-24 2021-11-24 Nucleic acid extraction plate with sealing film Active CN216236963U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122896844.7U CN216236963U (en) 2021-11-24 2021-11-24 Nucleic acid extraction plate with sealing film

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122896844.7U CN216236963U (en) 2021-11-24 2021-11-24 Nucleic acid extraction plate with sealing film

Publications (1)

Publication Number Publication Date
CN216236963U true CN216236963U (en) 2022-04-08

Family

ID=80956043

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122896844.7U Active CN216236963U (en) 2021-11-24 2021-11-24 Nucleic acid extraction plate with sealing film

Country Status (1)

Country Link
CN (1) CN216236963U (en)

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