CN216192366U - Production device for preparing spirulina small molecule peptide with immunoregulation activity - Google Patents
Production device for preparing spirulina small molecule peptide with immunoregulation activity Download PDFInfo
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- CN216192366U CN216192366U CN202122387241.4U CN202122387241U CN216192366U CN 216192366 U CN216192366 U CN 216192366U CN 202122387241 U CN202122387241 U CN 202122387241U CN 216192366 U CN216192366 U CN 216192366U
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Abstract
The utility model discloses a production device for preparing spirulina small molecular peptides with immunoregulatory activity, which comprises a hydrolysis tank, a single-layer positive pressure filter, activated carbon fiber membrane equipment, multifunctional inorganic ceramic membrane separation equipment, a nanofiltration membrane desalination concentrator, a high-speed tube array separator, tube array high-temperature instantaneous sterilization equipment and a high-speed centrifugal spray drying granulator. According to the method, the air guide pipe is arranged at the position of the feeding pipe of the hydrolysis tank, and the blower and the dust removal filter are used for providing clean air for the air guide pipe, so that the spirulina dry powder raw material entering the hydrolysis tank is fully dispersed, the caking and adhesion are avoided, and the full hydrolysis treatment in the hydrolysis tank is facilitated; in addition, this application is right through utilizing water bath heating jacket the hydrolysis tank carries out the even heating, avoids hydrolysis tank temperature rise too fast to influence the inactivation of hydrolase.
Description
Technical Field
The utility model relates to the technical field of food bioengineering, in particular to a production device for preparing spirulina small molecule peptide with immunoregulation activity.
Background
When the spirulina dry powder raw material is conventionally added into a hydrolysis tank for hydrolysis treatment, the spirulina dry powder raw material in the hydrolysis tank is not dispersed enough due to the thick feeding flange pipe, so that the spirulina dry powder raw material is agglomerated or attached to the inner wall of the hydrolysis tank, the spirulina dry powder raw material is not convenient to stir and mix, and the mixing and hydrolysis efficiency is reduced; in addition, when the conventional hydrolysis tank is heated, the temperature of the heating equipment is increased too fast, and the inactivation of the hydrolytic enzyme is easily caused.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a production device for preparing spirulina small molecule peptides with immunoregulatory activity, which solves the problems that the raw material feeding of spirulina dry powder is not easy to disperse and the conventional hydrolysis heating is easy to cause enzyme inactivation in the production process of the conventional spirulina small molecule peptides.
In order to solve the technical problems, the utility model adopts the following technical scheme:
the utility model provides a production device for preparing spirulina small molecule peptide with immunoregulation activity,
comprises a hydrolysis tank for the hydrolysis treatment of spirulina dry powder raw materials, a single-layer positive pressure filter for removing slag of enzymatic hydrolysate obtained by the treatment of the hydrolysis tank, an activated carbon fiber membrane device for decoloring and deodorizing filtered clear liquid obtained by the treatment of the single-layer positive pressure filter, and a multifunctional inorganic ceramic membrane separation device for performing ultrafiltration and slag removal on decolored and deodorized liquid treated by the activated carbon fiber membrane device, a nanofiltration membrane desalination concentrator for concentrating and desalinating the filtrate obtained by the treatment of the multifunctional inorganic ceramic membrane separation equipment, a high-speed tube array separator for separating and purifying the concentrated solution obtained by the treatment of the nanofiltration membrane desalination concentrator, a tube array high-temperature instantaneous sterilization equipment for sterilizing the separated and purified clear solution obtained by the treatment of the high-speed tube array separator, and a high-speed centrifugal spray drying granulator for drying the concentrated solution reaching the sterilization effect;
the top of the hydrolysis tank is provided with a feeding flange pipe, an air pressure balance pipe and a stirring motor for driving a stirring rod positioned in the hydrolysis tank;
the side wall of the hydrolysis tank is provided with an air guide pipe blowing towards the feeding flange pipe, the air guide pipe provides positive pressure air through a blower, and an air inlet of the blower is communicated with a dust removal filter, so that the spirulina dry powder raw material passing through the feeding flange pipe is uniformly fed into the hydrolysis tank;
the hydrolysis tank is characterized in that a water bath heating sleeve is arranged outside the hydrolysis tank, the bottom of the water bath heating sleeve is communicated with a heating water tank through a water inlet pipe, a water bath water supply pump is arranged on the water inlet pipe, and a water outlet pipe for heating water to flow back to the heating water tank is arranged at the top of the water bath heating sleeve.
In this embodiment, further optimize, set up the filter screen on the atmospheric pressure balance pipe, be convenient for atmospheric pressure balance in the jar of hydrolysising plays stable effect, prevents simultaneously that external environment micronic dust from falling into in the jar of hydrolysising to and prevent that spirulina dry powder raw materials from being blown out.
In this embodiment, optimize still further, install the stirring leaf on the puddler, in this embodiment, the stirring leaf is similar to the shape of ship anchor, is convenient for improve the even degree of compounding.
In this embodiment, it is still further optimized that the dust removal filter includes a box body with an opening on a side wall, and a molecular sieve and activated carbon filled in the box body.
In this embodiment, it is further optimized that the air outlet direction of the air guide pipe is perpendicular to the blanking direction of the feeding flange pipe, so as to facilitate the improvement of the dispersion uniformity of the spirulina dry powder entering the hydrolysis tank.
In this embodiment, optimize still further, be provided with temperature sensor in the jar of hydrolysising, the temperature of water in the heating water tank passes through temperature sensor as negative feedback adjustment signal, is convenient for keep the jar temperature of hydrolysising to be in suitable temperature demand.
Compared with the prior art, the utility model has the beneficial technical effects that:
according to the method, the air guide pipe is arranged at the position of the feeding pipe of the hydrolysis tank, and the blower and the dust removal filter are used for providing clean air for the air guide pipe, so that the spirulina dry powder raw material entering the hydrolysis tank is fully dispersed, the caking and adhesion are avoided, and the full hydrolysis treatment in the hydrolysis tank is facilitated; in addition, this application is right through utilizing water bath heating jacket the hydrolysis tank carries out the even heating, avoids hydrolysis tank temperature rise too fast to influence the inactivation of hydrolase.
Drawings
The utility model is further illustrated in the following description with reference to the drawings.
FIG. 1 is a schematic diagram of a main body of a production apparatus for preparing a spirulina small molecule peptide with immunoregulatory activity according to the present invention;
FIG. 2 is a schematic view of the inside of a hydrolysis tank of a production apparatus for producing a spirulina small molecule peptide having an immunoregulatory activity according to the present invention;
FIG. 3 is a schematic diagram of an external water jacket of a production device for preparing spirulina small molecule peptide with immunoregulatory activity.
Description of reference numerals:
1. a hydrolysis tank; 1a, feeding flange pipes; 1b, an air pressure balance pipe; 2. a stirring motor; 2a, a stirring rod; 2b, stirring blades; 3. a blower; 3a, a dust removal filter; 3b, an air guide pipe; 4. a water bath heating jacket; 4a, a water outlet pipe; 4b, a water inlet pipe; 5. a water bath water supply pump; 6. and heating the water tank.
Detailed Description
As shown in FIG. 1, this example discloses a device for producing spirulina small molecule peptide with immunoregulatory activity,
comprises a hydrolysis tank for the hydrolysis treatment of spirulina dry powder raw materials, a single-layer positive pressure filter for removing slag of enzymatic hydrolysate obtained by the treatment of the hydrolysis tank, an activated carbon fiber membrane device for decoloring and deodorizing filtered clear liquid obtained by the treatment of the single-layer positive pressure filter, and a multifunctional inorganic ceramic membrane separation device for performing ultrafiltration and slag removal on decolored and deodorized liquid treated by the activated carbon fiber membrane device, a nanofiltration membrane desalination concentrator for concentrating and desalinating the filtrate obtained by the treatment of the multifunctional inorganic ceramic membrane separation equipment, a high-speed tube array separator for separating and purifying the concentrated solution obtained by the treatment of the nanofiltration membrane desalination concentrator, a tube array high-temperature instantaneous sterilization equipment for sterilizing the separated and purified clear solution obtained by the treatment of the high-speed tube array separator, and a high-speed centrifugal spray drying granulator for drying the concentrated solution reaching the sterilization effect;
applying the principle of the structure:
1) the raw materials are preferably as follows: 350kg of spirulina dry powder raw material of the spirulina platensis is qualified after inspection and identified as spirulina dry powder raw material of the spirulina platensis through shape and molecule;
2) preparing a spirulina solution: preparing a spirulina dry powder solution according to a material-liquid ratio of 1:10, heating to 54 ℃, and then fully stirring for 1 h;
3) step-by-step enzymolysis: adding cellulase accounting for 0.15 percent of the weight of the spirulina dry powder and pectinase accounting for 0.15 percent of the weight of the spirulina dry powder into the spirulina solution extracted in the step (2), performing enzymolysis for 2 hours sufficiently to enable protein to be fully dissociated, then adding compound protease accounting for 0.2 percent of the weight of the spirulina dry powder and xylanase accounting for 0.1 percent of the weight of the spirulina dry powder, performing enzymolysis for 1-2 hours, and inactivating enzyme for 20 minutes at 85 ℃;
4) filtering and deslagging: centrifugal deslagging: removing residues from the enzyme-deactivated and sterilized enzymolysis solution by a single-layer positive pressure filter, completely separating spirulina residues and liquid in the enzymolysis solution, wherein the filtering temperature is 55 ℃, and the working pressure is 0.3 MPa;
5) decoloring and deodorizing: cooling the filtered clear liquid obtained in the step (4) to 50 ℃, and then decoloring and deodorizing by using activated carbon fiber membrane equipment;
6) membrane separation: ultrafiltering the decolorized fishy smell removing solution by a multifunctional inorganic ceramic membrane separation device, efficiently removing impurities, filtering the filtrate to a clear solution storage tank, wherein the filtering temperature is 60 ℃, and the filtering pressure is 0.2 MPa;
7) and (3) nanofiltration membrane desalination and concentration: concentrating and desalting the filtrate by using a nanofiltration membrane device, wherein the concentration of the polypeptide solution is controlled to be 5% before concentration, the concentration of the concentrated material reaches 12%, the operating pressure is 1.5MPa, and the operating temperature is 35 ℃;
8) high-speed tubular separation: the concentrated solution is separated by a high-speed tubular separator, so that the feed liquid is highly purified and has no impurities; the simple separation rotating speed is 16000r/min, and the separation factor is as follows: 15050 R.C.F;
9) tubular high-temperature instantaneous sterilization: and (3) sterilizing the separated clear liquid by adopting a tube array type high-temperature instantaneous sterilization device, wherein the sterilization temperature is as follows: 120 ℃, discharge temperature 50 ℃:
10) high-speed centrifugal spray drying: and (3) performing powder spraying drying on the concentrated solution reaching the sterilization effect by using a high-speed centrifugal spray drying granulator, wherein the air inlet temperature is 190 ℃ and the air outlet temperature is 97 ℃.
As shown in figure 2 of the drawings, in which,
in the embodiment, a feeding flange pipe 1a, an air pressure balance pipe 1b and a stirring motor 2 for driving a stirring rod 2a positioned in the hydrolysis tank 1 are arranged at the top of the hydrolysis tank 1;
the side wall of the hydrolysis tank 1 is provided with an air guide pipe 3b blowing towards the feeding flange pipe 1a, the air guide pipe 3b provides positive pressure air through an air blower 3, and an air inlet of the air blower 3 is communicated with a dust removal filter 3a, so that the spirulina dry powder raw material passing through the feeding flange pipe 1a can be uniformly fed into the hydrolysis tank 1;
in the process of feeding the spirulina dry powder raw material into the hydrolysis tank 1 through the feeding flange pipe 1a, the spirulina dry powder raw material is easily adhered together, so that the spirulina dry powder raw material is not easily stirred uniformly and is also easily adhered to the inner wall of the hydrolysis tank;
in this embodiment, the clean air processed by the dust removal filter 3a is sent into the hydrolysis tank 1 by using the blower 3, wherein the air outlet direction of the air guide pipe 3b is perpendicular to the feeding direction of the feeding flange pipe 1a, so that the spirulina dry powder raw material entering the hydrolysis tank 1 is blown away or uniformly dispersed, and is easily and uniformly mixed with hydrolysis, and the hydrolysis reaction efficiency is improved;
in this embodiment, when the blower 3 blows clean air into the hydrolysis tank 1, the air pressure in the hydrolysis tank 1 is inevitably increased, and in order to balance the internal air pressure of the hydrolysis tank 1 and prevent the spirulina dry powder raw material entering the hydrolysis tank 1 from escaping with the pressurized air, in this embodiment, a filter screen is installed on the air pressure balance pipe 1 b;
in the present embodiment, as shown in fig. 2, the stirring rod 2a is provided with a stirring blade 2b, wherein the stirring blade 2b is shaped like a ship anchor section, so as to facilitate scraping off the raw material attached to the inner wall of the hydrolysis tank 1;
the dust removing filter 3a comprises a box body with an opening on the side wall, and a molecular sieve and activated carbon filled in the box body, so that impurity particles and harmful gas in the air are adsorbed by the molecular sieve and the activated carbon.
As shown in figure 3 of the drawings,
in the preparation step of the spirulina solution: preparing a spirulina dry powder solution according to a material-liquid ratio of 1:10, heating to 54 ℃, and then fully stirring for 1h, so that water bath heating is needed to meet the temperature rise requirement;
in this embodiment, a water bath heating jacket 4 is installed outside the hydrolysis tank 1, the bottom of the water bath heating jacket 4 is communicated with a heating water tank 6 through a water inlet pipe 4b, a water bath water supply pump 5 is installed on the water inlet pipe 4b, and a water outlet pipe 4a for returning heating water to the heating water tank 6 is installed at the top of the water bath heating jacket 4;
install temperature sensor in the hydrolysis tank 1, the temperature in the heating water tank 6 passes through temperature sensor as negative feedback adjustment signal, in this embodiment, through utilizing water bath heating jacket 4 is right hydrolysis tank 1 carries out the water bath heating to according to negative feedback adjustment, improve 1 heating stability to hydrolysis tank, prevent the deactivation of resolvase.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used for convenience of description only, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.
The above embodiments are only for describing the preferred mode of the present invention, and do not limit the scope of the present invention, and various modifications and improvements of the technical solution of the present invention by those skilled in the art should fall within the protection scope defined by the claims of the present invention without departing from the spirit of the present invention.
Claims (6)
1. A apparatus for producing for preparing spirulina small molecule peptide with immunoregulation activity, its characterized in that:
comprises a hydrolysis tank for the hydrolysis treatment of spirulina dry powder raw materials, a single-layer positive pressure filter for removing slag of enzymatic hydrolysate obtained by the treatment of the hydrolysis tank, an activated carbon fiber membrane device for decoloring and deodorizing filtered clear liquid obtained by the treatment of the single-layer positive pressure filter, and a multifunctional inorganic ceramic membrane separation device for performing ultrafiltration and slag removal on decolored and deodorized liquid treated by the activated carbon fiber membrane device, a nanofiltration membrane desalination concentrator for concentrating and desalinating the filtrate obtained by the treatment of the multifunctional inorganic ceramic membrane separation equipment, a high-speed tube array separator for separating and purifying the concentrated solution obtained by the treatment of the nanofiltration membrane desalination concentrator, a tube array high-temperature instantaneous sterilization equipment for sterilizing the separated and purified clear solution obtained by the treatment of the high-speed tube array separator, and a high-speed centrifugal spray drying granulator for drying the concentrated solution reaching the sterilization effect;
the top of the hydrolysis tank is provided with a feeding flange pipe, an air pressure balance pipe and a stirring motor for driving a stirring rod positioned in the hydrolysis tank;
the side wall of the hydrolysis tank is provided with an air guide pipe blowing towards the feeding flange pipe, the air guide pipe provides positive pressure air through a blower, and an air inlet of the blower is communicated with a dust removal filter, so that the spirulina dry powder raw material passing through the feeding flange pipe is uniformly fed into the hydrolysis tank;
the hydrolysis tank is characterized in that a water bath heating sleeve is arranged outside the hydrolysis tank, the bottom of the water bath heating sleeve is communicated with a heating water tank through a water inlet pipe, a water bath water supply pump is arranged on the water inlet pipe, and a water outlet pipe for heating water to flow back to the heating water tank is arranged at the top of the water bath heating sleeve.
2. The apparatus for producing a spirulina small molecule peptide having immunomodulatory activity of claim 1, wherein: and a filter screen is arranged on the air pressure balance pipe.
3. The apparatus for producing a spirulina small molecule peptide having immunomodulatory activity of claim 1, wherein: and the stirring rod is provided with a stirring blade.
4. The apparatus for producing a spirulina small molecule peptide having immunomodulatory activity of claim 1, wherein: the dust removal filter comprises a box body with an opening on the side wall, and a molecular sieve and activated carbon filled in the box body.
5. The apparatus for producing a spirulina small molecule peptide having immunomodulatory activity of claim 1, wherein: the air outlet direction of the air guide pipe is perpendicular to the blanking direction of the feeding flange pipe.
6. The apparatus for producing a spirulina small molecule peptide having immunomodulatory activity of claim 1, wherein: a temperature sensor is arranged in the hydrolysis tank, and the water temperature in the heating water tank is used as a negative feedback adjusting signal through the temperature sensor.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122387241.4U CN216192366U (en) | 2021-09-30 | 2021-09-30 | Production device for preparing spirulina small molecule peptide with immunoregulation activity |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122387241.4U CN216192366U (en) | 2021-09-30 | 2021-09-30 | Production device for preparing spirulina small molecule peptide with immunoregulation activity |
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| CN216192366U true CN216192366U (en) | 2022-04-05 |
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| CN202122387241.4U Active CN216192366U (en) | 2021-09-30 | 2021-09-30 | Production device for preparing spirulina small molecule peptide with immunoregulation activity |
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20221109 Address after: 031800 Primary Peptide Industrial Park, Jicheng Town, Yushe County, Jinzhong City, Shanxi Province Patentee after: Shanxi Native Peptide Technology Co.,Ltd. Address before: 100000 room 402, gate 1, building 6, dongshengyuan apartment dormitory, Haidian District, Beijing Patentee before: Wu Wei |
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| TR01 | Transfer of patent right |