CN216192273U

CN216192273U - Automatic sampling device

Info

Publication number: CN216192273U
Application number: CN202122734152.2U
Authority: CN
Inventors: 高颖; 雒燕婷
Original assignee: Zhejiang Moda Biotechnology Co ltd
Current assignee: Zhejiang Moda Biotechnology Co ltd
Priority date: 2021-11-09
Filing date: 2021-11-09
Publication date: 2022-04-05
Anticipated expiration: 2031-11-09

Abstract

The utility model relates to an automatic sampling device, which comprises an electric turntable, a sample injection device, a lighting device and a sample injection pump; the electric turntable is circumferentially provided with a plurality of uniformly arranged sample injection grooves, and the electric turntable can rotate to enable the sample injection grooves to pass through the sample injection device and the lighting device one by one; the sample injection device is positioned above the electric turntable and is communicated with the sample injection pump, so that a sample injection groove which is moved to the lower part of the sample injection device can be injected with a sample solution to be detected through the sample injection pump; the lighting device is provided with an optical fiber sampling head which can collect chemiluminescence in a sample solution to be detected; the bottom of the sample injection pump is connected with a container bottle filled with a sample solution to be detected and communicated with the sample injection device through a conduit. The application can be used for virus detection of ATP synthase, and whether a sample has target viruses or not can be judged by collecting fluorescence through the lighting device.

Description

Automatic sampling device

Technical Field

The utility model relates to the technical field of virus detection, in particular to an automatic sampling device.

Background

In the existing technology for virus detection by utilizing ATP synthase, manual operation is usually required for sampling, namely, a sample solution to be detected is dripped into a reaction container through a dropper to react with an ATP synthase biosensor connected with virus nucleic acid, once target virus exists in the sample solution to be detected, the ATP synthase biosensor connected with the virus nucleic acid can be connected with the virus in the sample solution to be detected to generate fluorescence, and therefore, whether the target virus exists in the sample solution to be detected can be judged only by detecting the fluorescence. However, in this process, the manual operation efficiency is low, and the amount of the sample solution to be measured dropped by the dropper each time cannot be well controlled.

Therefore, an automatic sampling device capable of automatically sampling and improving the detection efficiency is needed.

SUMMERY OF THE UTILITY MODEL

The present invention addresses the above-identified problems in the prior art by providing an automatic sampling device.

In order to realize the purpose of the utility model, the utility model adopts the following technical scheme: the automatic sampling device comprises an electric turntable, a sample injection device, a lighting device and a sample injection pump; the electric turntable is circumferentially provided with a plurality of uniformly arranged sample injection grooves, and the electric turntable can rotate to enable the sample injection grooves to pass through the sample injection device and the lighting device one by one; the sample injection device is positioned above the electric turntable and is communicated with the sample injection pump, so that a sample injection groove which is moved to the lower part of the sample injection device can be injected with a sample solution to be detected through the sample injection pump; the lighting device is provided with an optical fiber sampling head which can collect chemiluminescence in a sample solution to be detected; the bottom of the sample injection pump is connected with a container bottle filled with a sample solution to be detected and communicated with the sample injection device through a conduit.

The working principle and the beneficial effects are as follows: 1. compared with the prior art, when the sample injection device is used, a sample solution to be detected in a container bottle is input to the sample injection device through the guide pipe by the sample injection pump, the sample injection device performs sample injection operation on a sample injection groove below the sample injection device in a rotating manner, the ATP synthase biosensor connected with target virus nucleic acid is placed in the sample injection groove in advance, so that after reaction in each sample injection groove lasts for a period of time, the electric turntable can be rotated again, the sample injection groove sequentially passes through the lower part of the lighting device, fluorescence information is collected by the optical fiber sampling head of the lighting device, the effect of rapid detection can be achieved, the detection efficiency is remarkably improved, the amount of the sample solution to be detected dripped each time can be accurately controlled, and interference is reduced;

2. due to the arrangement of the plurality of sample injection grooves, ATP synthase biosensors connected with different target virus nucleic acids can be placed in different sample injection grooves, so that whether a plurality of viruses exist in a sample solution to be detected or which viruses exist in the sample solution to be detected can be quickly detected, the viruses to be detected in the sample solution to be detected are all determined in advance, if new coronavirus needs to be detected, only the ATP synthase biosensors connected with new coronavirus nucleic acids are placed, and the purpose of the method is not to detect unknown viruses but to detect known viruses.

Further, the electric turntable comprises a circular turntable and a driving motor for driving the electric turntable to rotate, so that each sample injection groove is moved to rotate by one station through each rotation of the driving motor, and the number of the stations is consistent with that of the sample injection grooves. This sets up, can make at every turn circular carousel rotate once can both make annotate the appearance groove and rotate to required station on, do not need other positioner, show to have reduced the location degree of difficulty, and positioning accuracy is high.

Further, the number of the sample injection grooves is 8-12. According to the arrangement, multiple target viruses can be detected simultaneously.

Further, annotate and be equipped with a plurality of notes appearance heads on the appearance device, just circular carousel rotates once, annotate a kind groove all can with annotate the appearance head and aim at. By the arrangement, various target viruses can be detected simultaneously, and the detection efficiency can be greatly improved.

Furthermore, annotate and be equipped with 3 on the appearance device and annotate appearance heads. The three sample injection grooves can be injected with samples at the same time.

Further, still include the shell body, electric turntable, annotate appearance device, daylighting device and annotate the appearance pump and all install in the cavity of shell body. The outer shell provides an installation environment, and can effectively protect internal parts.

Further, the number of the sample injection pumps is at least two, and each sample injection pump is in threaded fit with the container bottle. The arrangement can conveniently replace the container bottle and also can realize the detection of at least two sample solutions to be detected.

Further, the electric turntable and the sample injection pump are fixed on the inner wall of the outer shell through connecting pieces. The installation and the dismantlement are convenient.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of a sampling device;

figure 3 is a schematic view of a daylighting device.

In the figure, 1, an outer shell; 2. an electric turntable; 3. a sample injection device; 4. a lighting device; 5. a sample injection pump; 6. a container bottle; 21. a circular turntable; 22. a drive motor; 211. injecting a sample groove; 31. injecting a sample head; 41. an optical fiber sampling head.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments that can be derived by one of ordinary skill in the art from the embodiments given herein are intended to be within the scope of the present invention.

It will be understood by those skilled in the art that in the present disclosure, the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in an orientation or positional relationship indicated in the drawings for ease of description and simplicity of description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, the above terms should not be construed as limiting the present invention.

As shown in fig. 1-3, the automatic sampling device includes an electric rotary disc 2, a sample injection device 3, a lighting device 4 and a sample injection pump 5, wherein the electric rotary disc 2, the sample injection device 3, the lighting device 4 and the sample injection pump 5 are all installed in an open outer casing 1, and a baffle plate can be adopted to shield the structures of the sample injection pump 5 and the electric rotary disc 2, and part of the conducting wires and the conducting pipes.

Specifically, electric turntable 2 circumference is equipped with a plurality of notes appearance groove 211 that evenly set up, and this electric turntable 2 can rotate and realize annotating appearance groove 211 and annotating appearance device 3 and daylighting device 4 one by one, and electric turntable 2 includes circular carousel 21 and is used for driving the rotatory driving motor 22 of this electric turntable 2 to make and rotate every notes appearance groove 211 through this driving motor 22 once and rotate a station of every representative removal, station quantity and notes appearance groove 211 quantity unanimous, preferably, notes appearance groove 211 quantity is 8 ~ 12. Can make at every turn circular carousel 21 rotate once can both make annotate appearance groove 211 rotatory to the station that needs arrive, do not need other positioner, show and reduce the location degree of difficulty, and positioning accuracy is high, also can realize detecting multiple virus, or set up to detect and improve the detection accuracy degree many times.

Specifically, annotate appearance device 3 and be located this electric turntable 2 top and with annotate appearance pump 5 intercommunication to make and to annotate the appearance groove 211 of annotating that the appearance device 3 below is moved to and to pour into the sample solution that awaits measuring through this annotate appearance pump 5, annotate and be equipped with a plurality of notes appearance heads 31 on the appearance device 3, and circular turntable 21 rotates once, annotate appearance groove 211 and all can aim at with annotating appearance head 31. This setting can detect multiple target virus simultaneously, can greatly improve detection efficiency, wherein annotate and be equipped with 3 on the appearance device 3 and annotate appearance head 31, the relative quantity of annotating appearance pump 5 is two at least, and every

annotates appearance pump

5 and 6 spiro union cooperations of container bottle, and every annotates 5 bottoms of appearance pump and is connected with the container bottle 6 that is equipped with the sample solution that awaits measuring and communicates with annotating appearance device 3 through the pipe. Due to the arrangement of the plurality of sample injection grooves 211, ATP synthase biosensors connected with different target virus nucleic acids can be placed in different sample injection grooves 211, so that whether a plurality of viruses exist in a sample solution to be detected or which viruses exist in the sample solution to be detected can be quickly detected, because the viruses to be detected by the sample solution to be detected are all determined in advance, if new coronavirus needs to be detected, only the ATP synthase biosensors connected with new coronavirus nucleic acids are placed, and the method aims at detecting not unknown viruses but known viruses.

Specifically, the lighting device 4 is provided with an optical fiber sampling head 41 capable of collecting chemiluminescence in a sample solution to be tested, the optical fiber sampling head 41 is the prior art, and a means for analyzing fluorescence to obtain a virus is also the prior art, so that the present application does not have any improvement on a computer method, and only the structural improvement design is provided.

Compared with the prior art, this application is when using, through annotating a kind pump 5 with the sample solution that awaits measuring in the container bottle 6 through pipe input to annotating a kind device 3, annotate a kind operation to the notes appearance groove 211 of this below through annotating a kind device 3 pairing rotation, placed the ATP synthase biosensor that is connected with target virus nucleic acid in advance in annotating a kind groove 211, so after every reaction period of annotating in kind groove 211, can rotate electric turntable 2 once more, pass through daylighting device 4 below in proper order, rely on daylighting device 4's optical fiber sampling head 41 to gather fluorescence information, so can play the effect of short-term test, the detection efficiency has been showing and has been improved, the volume of the sample solution that awaits measuring that drips into at every turn can both accurate control, interference reduction, and can detect many times and improve the detection accuracy or detect multiple virus.

The present invention is not described in detail in the prior art, and therefore, the present invention is not described in detail.

It is understood that the terms "a" and "an" should be interpreted as meaning that a number of one element or element is one in one embodiment, while a number of other elements is one in another embodiment, and the terms "a" and "an" should not be interpreted as limiting the number.

Although terms such as the outer housing 1, the electric turntable 2, the sample injection device 3, the lighting device 4, the sample injection pump 5, the container bottle 6, the circular turntable 21, the driving motor 22, the sample injection groove 211, the sample injection head 31, the optical fiber sampling head 41, etc. are used more frequently, the possibility of using other terms is not excluded. These terms are used merely to more conveniently describe and explain the nature of the present invention; they are to be construed as being without limitation to any additional limitations that may be imposed by the spirit of the present invention.

The present invention is not limited to the above-mentioned preferred embodiments, and any other products in various forms can be obtained by anyone in the light of the present invention, but any changes in the shape or structure thereof, which have the same or similar technical solutions as the present application, fall within the protection scope of the present invention.

Claims

1. The automatic sampling device is characterized by comprising an electric turntable, a sample injection device, a lighting device and a sample injection pump; the electric turntable is circumferentially provided with a plurality of uniformly arranged sample injection grooves, and the electric turntable can rotate to enable the sample injection grooves to pass through the sample injection device and the lighting device one by one; the sample injection device is positioned above the electric turntable and is communicated with the sample injection pump, so that a sample injection groove which is moved to the lower part of the sample injection device can be injected with a sample solution to be detected through the sample injection pump; the lighting device is provided with an optical fiber sampling head which can collect chemiluminescence in a sample solution to be detected; the bottom of the sample injection pump is connected with a container bottle filled with a sample solution to be detected and communicated with the sample injection device through a conduit.

2. The automatic sampling device of claim 1, wherein the electric turntable comprises a circular turntable and a driving motor for driving the electric turntable to rotate, so that each sample injection groove is moved to rotate by one station represented by one rotation of the driving motor, and the number of stations is consistent with the number of sample injection grooves.

3. The automatic sampling device of claim 2, wherein the number of the sample injection grooves is 8-12.

4. The automatic sampling device of claim 3, wherein a plurality of sample injection heads are provided on the sample injection device, and the sample injection groove can be aligned with the sample injection heads for each rotation of the circular turntable.

5. The automatic sampling device of claim 4, wherein 3 sample injection heads are provided on the sample injection device.

6. The automatic sampling device of claim 1, further comprising an outer housing, wherein the motorized turntable, the sample injection device, the light collection device, and the sample injection pump are all mounted within a cavity of the outer housing.

7. The automatic sampling device of claim 1, wherein the number of said priming pumps is at least two, and each of said priming pumps is threadably engaged with said container bottle.

8. The automatic sampling device of claim 6, wherein the electric rotary disk and the sample injection pump are fixed on the inner wall of the outer shell through connecting pieces.