CN216170571U

CN216170571U - Separation device for immune cells in poultry thymus

Info

Publication number: CN216170571U
Application number: CN202122455447.6U
Authority: CN
Inventors: 计坚; 李莹; 程嘉恒; 罗成龙
Original assignee: Institute of Animal Science of Guangdong Academy of Agricultural Sciences
Current assignee: Institute of Animal Science of Guangdong Academy of Agricultural Sciences
Priority date: 2021-10-12
Filing date: 2021-10-12
Publication date: 2022-04-05
Anticipated expiration: 2031-10-12

Abstract

The utility model discloses a separation device for immune cells in poultry thymus, which comprises a separation box, wherein the bottom end of the separation box is fixedly connected with a plurality of support columns, the separation box is provided with a separation groove, a centrifugal box is arranged in the separation groove, the upper end of the centrifugal box is connected with a drive shaft, the centrifugal box is provided with a processing groove, an erection plate is arranged in the processing groove, the bottom end of the erection plate is rotatably connected with a threaded rod, the bottom end of the separation box is provided with a vertical groove, the bottom end of the threaded rod extends into the vertical groove, and one side of the vertical groove is provided with a discharge pipe communicated with the outside. According to the utility model, through the centrifugal box, the driving shaft, the erection plate, the threaded rod and the filter plate, after the thymus tissue is subjected to centrifugal separation, the tissue fluid containing immune cells is directly discharged through the bottom end to be separated from the thymus tissue, so that the efficiency and the quality of immune cell extraction are effectively improved.

Description

Separation device for immune cells in poultry thymus

Technical Field

The utility model relates to the technical field of immune cell separation, in particular to a separation device for immune cells in the thymus of poultry.

Background

Immune cells refer to cells involved in or associated with an immune response. Including lymphocytes, dendritic cells, monocytes/macrophages, granulocytes, mast cells, and the like. Immune cells can be classified into various types, and various immune cells play an important role in the human body. The knowledge of the avian immune system is mostly from the study of chickens, and the immune mechanisms of chickens and mammals have many similarities, but the two also have important differences. At present, in the process of extracting immune cells in the thymus of poultry, the immune cells are usually extracted by adopting a centrifugal force mode, but in the existing process of separating the immune cells from the thymus tissue, separated tissue needs to be taken out and then separated, so that not only is time wasted, but also the thymus tissue is mixed with the immune cells again, and the quality of extracting the immune cells is reduced.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the problems that in the existing separation process of immune cells and thymus tissues, separated tissues need to be taken out and separated, so that time is wasted, and the thymus tissues are mixed with the immune cells again, so that the quality of immune cell extraction is reduced.

In order to achieve the purpose, the utility model adopts the following technical scheme:

the utility model provides a separator of immune cell in poultry thymus, includes the separator box, separator box bottom end fixedly connected with a plurality of support columns, the separating tank has been seted up to the separator box, be provided with the centrifugal box in the separating tank, the centrifugal box upper end is connected with the drive shaft, the processing groove has been seted up to the centrifugal box, be provided with the set up board in the processing groove, set up the board bottom and rotate and be connected with the threaded rod, vertical groove has been seted up to the separator box bottom, the threaded rod bottom extends to vertical inslot, vertical groove one side is provided with the outside row of intercommunication material pipe.

Preferably, the two sides of the upper end of the processing tank are provided with blanking ports in a penetrating mode, and the side wall of the separation tank, which is positioned at the upper ends of the two blanking ports, is provided with a feeding port in a penetrating mode.

Preferably, the separator box upper end is provided with the drive block, the drive groove has been seted up to the drive block, drive groove fixedly connected with limiting plate, limiting plate fixedly connected with motor, the drive shaft upper end runs through in the separator groove lateral wall extends to the drive groove to fixed connection is on the output of motor.

Preferably, the side wall of the processing tank at the upper end of the erection plate is fixedly connected with a filter plate, and the filter plate is abutted against the upper end of the erection plate.

Preferably, the sliding tray has all been seted up to processing groove both sides, two the processing groove lateral wall is all run through to the sliding tray bottom to extend to vertical inslot, set up the equal fixedly connected with joint board in board both sides, two the joint board is located the sliding tray of both sides respectively, and with sliding tray lateral wall sliding connection.

Preferably, the bottom end of the threaded rod penetrates through the side wall of the vertical groove and extends to the outside, and the bottom end of the threaded rod is fixedly connected with a knob.

Compared with the prior art, the utility model has the beneficial effects that: through centrifugal box, drive shaft, set up board, threaded rod and filter, can carry out centrifugal separation back to thymus tissue, directly discharge the interstitial fluid that contains immune cell through the bottom, with thymus tissue separation, effectual efficiency and the quality of extracting immune cell that has improved.

Drawings

FIG. 1 is a schematic view of the external appearance structure of the main body of the present invention;

FIG. 2 is a schematic cross-sectional front view of the present invention;

FIG. 3 is a schematic side sectional view of the present invention.

In the figure: 1 separator box, 2 support columns, 3 centrifuge boxes, 4 drive shafts, 5 erection plates, 6 threaded rods, 7 discharge pipes, 8 blanking ports, 9 feed inlets, 10 drive blocks, 11 motors, 12 filter plates, 13 clamping plates and 14 knobs.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1-3, the embodiment of the utility model provides a separation device for immune cells in poultry thymus, which comprises a separation box 1, wherein a plurality of support columns 2 are fixedly connected to the bottom end of the separation box 1, a separation groove is formed in the separation box 1, a centrifugal box 3 is arranged in the separation groove, a drive shaft 4 is connected to the upper end of the centrifugal box 3, a processing groove is formed in the centrifugal box 3, an erection plate 5 is arranged in the processing groove, a threaded rod 6 is rotatably connected to the bottom end of the erection plate 5, a vertical groove is formed in the bottom end of the separation groove, the bottom end of the threaded rod 6 extends into the vertical groove, a discharge pipe 7 communicated with the outside is arranged on one side of the vertical groove, and the discharge pipe 7 is located on the bottom end of one side of the vertical groove.

Processing groove upper end both sides all run through and are equipped with blanking mouth 8, and the separating tank lateral wall that is located two 8 upper ends of blanking mouths runs through and is equipped with charge door 9, and when blanking mouth 8 and charge door 9 coincide, can be to the material that adds the needs separation in the separator box 3, when separator box 3 rotated, can avoid the material in the separator box 3 to be thrown away.

1 upper end of separator box is provided with drive block 10, and the drive groove has been seted up to drive block 10, drive groove fixedly connected with limiting plate, limiting plate fixedly connected with motor 11, and motor 11 is prior art, does not do here and gives unnecessary details, and the effect of limiting plate is the position of limiting

motor

11, and 4 upper ends of drive shaft run through the separating groove lateral wall and extend to in the drive groove to fixed connection is on motor 11's output.

The side wall of the processing tank at the upper end of the erection plate 5 is fixedly connected with a filter plate 12, the filter plate 12 is abutted against the upper end of the erection plate 5, and the filter plate 12 at the upper end of the erection plate 5 can effectively separate and filter the mixture in the separation box 3.

The sliding tray has all been seted up to processing groove both sides, and the processing groove lateral wall is all run through to two sliding tray bottoms to extend to vertical inslot, set up the equal fixedly connected with joint board 13 in 5 both sides of board, two joint boards 13 are located the sliding tray of both sides respectively, and with sliding tray lateral wall sliding connection, two joint board 13 not only can make separator box 3 drive set up board 5 and rotate, can also restrict the position of setting up board 5 and reciprocating.

The bottom end of the threaded rod 6 penetrates through the side wall of the vertical groove and extends to the outside, the bottom end of the threaded rod 6 is fixedly connected with a knob 14, and the height position of the erection plate 5 can be conveniently adjusted by rotating the threaded rod 6.

When the utility model is used, firstly, thymus tissue needing to extract immune cells is added into a separation box 3 through a feed inlet 9 and a blanking port 8, then a motor 11 is turned on, the output end of the motor 11 can drive a driving shaft 4 to rotate, the driving shaft 4 can drive the centrifugal box 3 to rotate, so that the thymus tissue in the centrifugal box 3 can be rotated, the immune cells are separated from the thymus tissue through centrifugal force, after the separation is finished, a knob 14 is needed to rotate a threaded rod 6, the threaded rod 6 can drive a setting plate 5 to move downwards, so that a mixture in the separation box 3 can be driven to move downwards, when the mixture moves downwards, the mixture can pass through a filter plate 12, the thymus tissue and other substances in the mixture can be filtered above the filter plate 12, the tissue containing the immune cells is discharged into a vertical groove, when the setting plate 5 moves to the bottom end of the vertical groove, the immune cell tissue on the upper end of the setting plate 5 can be discharged through the discharging pipe 7, and by the way, the efficiency and the quality of extracting immune cells can be effectively improved.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides a separator of immune cell in poultry thymus, includes separator box (1), its characterized in that, a plurality of support columns (2) of separator box (1) bottom fixedly connected with, the separating tank has been seted up in separator box (1), be provided with centrifugal box (3) in the separating tank, centrifugal box (3) upper end is connected with drive shaft (4), the processing groove has been seted up in centrifugal box (3), the processing inslot is provided with sets up board (5), it is connected with threaded rod (6) to set up board (5) bottom rotation, vertical groove has been seted up to the separating tank bottom, threaded rod (6) bottom extends to vertical inslot, vertical groove one side is provided with the outside row of material pipe (7) of intercommunication.

2. The device for separating immune cells in the thymus gland of poultry according to claim 1, wherein the processing tank is provided with a blanking port (8) through both sides of the upper end, and the sidewall of the separation tank on the upper end of the two blanking ports (8) is provided with a feeding port (9) through.

3. The device for separating immune cells from the thymus gland of poultry as claimed in claim 1, wherein a driving block (10) is disposed at the upper end of the separation box (1), a driving groove is formed in the driving block (10), the driving groove is fixedly connected with a limiting plate, the limiting plate is fixedly connected with a motor (11), and the upper end of the driving shaft (4) penetrates through the side wall of the separation groove to extend into the driving groove and is fixedly connected to the output end of the motor (11).

4. The device for separating immune cells from the thymus of poultry according to claim 1, characterized in that the side wall of the processing tank at the upper end of the setting plate (5) is fixedly connected with a filter plate (12), and the filter plate (12) is abutted against the upper end of the setting plate (5).

5. The device for separating immune cells in the thymus gland of poultry as claimed in claim 1, wherein sliding grooves are formed on both sides of the processing groove, the bottom ends of the two sliding grooves penetrate through the side wall of the processing groove and extend into the vertical groove, snap plates (13) are fixedly connected to both sides of the erection plate (5), and the two snap plates (13) are respectively located in the sliding grooves on both sides and are slidably connected with the side wall of the sliding groove.

6. The device for separating immune cells in the thymus gland of poultry according to claim 1, characterized in that the bottom end of the threaded rod (6) penetrates through the side wall of the vertical groove and extends to the outside, and the bottom end of the threaded rod (6) is fixedly connected with a knob (14).