CN216090934U

CN216090934U - Tissue clamping device and tissue repair equipment

Info

Publication number: CN216090934U
Application number: CN202121774645.2U
Authority: CN
Inventors: 孙圣洁; 肖振昕; 虞奇峰; 秦涛
Original assignee: Shanghai Newpulse Medical Technology Co ltd
Current assignee: Shanghai Newpulse Medical Technology Co ltd
Priority date: 2021-07-30
Filing date: 2021-07-30
Publication date: 2022-03-22
Anticipated expiration: 2031-07-30

Abstract

The application discloses a tissue clamping device and a tissue repair device. The tissue clamping device comprises a clamping component and an elastic supporting piece; the clamping assembly comprises a first clamping assembly and a second clamping assembly, and the first clamping assembly and the second clamping assembly are used for clamping tissues; the first clamping assembly comprises a first clamping arm, and the second clamping assembly comprises a second clamping arm; the elastic supporting piece comprises a first elastic supporting rod and a second elastic supporting rod; the middle part of first elasticity branch with first arm lock is connected or contacts, the middle part of second elasticity branch with the second arm lock is connected or contacts, first elasticity branch the middle part can for first arm lock motion, second elasticity branch the middle part can for the second arm lock motion.

Description

Tissue clamping device and tissue repair equipment

Technical Field

The present application relates to the field of medical devices, and more particularly to a tissue clamping device and a tissue repair device.

Background

In surgical repair of body tissue, it is often necessary to clamp and secure the tissue by means of a tissue clamping device. For example, in the treatment of mitral regurgitation, a more common cardiac disorder, the mitral valve is located between the left atrium and the left ventricle, and during left ventricular contraction, the mitral valve acts as a check valve to tightly close the atrioventricular orifice and prevent blood from flowing back from the left ventricle into the left atrium. However, when the mitral valve is diseased, it may happen that the mitral valve is difficult to close completely when the left ventricle contracts, so that the left atrium receives a large amount of blood backflow, which may cause a sharp rise in left atrium and pulmonary venous pressure, increase in left ventricle diastolic volume load, further cause a series of pathological changes such as left ventricle enlargement, pulmonary hypertension, and the like, and finally cause clinical manifestations such as heart failure, arrhythmia, and the like, and may be life-threatening in severe cases. In the operation of treating mitral valve regurgitation, the opposite sides of the mitral valve can be clamped by a tissue clamping device, so that the valve of the mitral valve is changed from a big hole into two small holes, the regurgitation area is reduced, and the mitral valve regurgitation is effectively prevented.

Similarly, the tissue gripping device may also be adapted to the tricuspid valve of the heart to achieve the effect of reducing the area of regurgitation by gripping the leaflets on both sides. Tricuspid valve disease is one of the most common heart valve diseases, with higher overall incidence than aortic valve disease, and most of them tricuspid insufficiency. The tricuspid valve has some structural similarities to the mitral valve. The normal tricuspid valve structure consists of an annulus, leaflets, chordae tendinae, and papillary muscles, and the relationship of the leaflets and their chordae tendineae to the papillary muscles play an important role in systolic tricuspid valve closure. Changes in the geometry and characteristics of the right ventricle can directly lead to tricuspid insufficiency, causing blood to flow from the right ventricle into the right atrium during systole. Treatment of tricuspid regurgitation may be classified into surgical treatment and interventional treatment, in addition to drug improvement. While edge-to-edge repair is considered an effective means for interventional treatment of tricuspid regurgitation, edge-to-edge clips are delivered via the femoral vein into the right atrium to secure the anterior leaflet to the margins of the septal and posterior leaflets, thereby reducing the leaflet opening area to reduce tricuspid regurgitation.

SUMMERY OF THE UTILITY MODEL

One of the embodiments of the present application provides a tissue clamping device, which includes a clamping assembly and an elastic supporting member; the clamping assembly comprises a first clamping assembly and a second clamping assembly, and the first clamping assembly and the second clamping assembly are used for clamping tissues; the first clamping assembly comprises a first clamping arm, and the second clamping assembly comprises a second clamping arm; the elastic supporting piece comprises a first elastic supporting rod and a second elastic supporting rod; the middle part of first elasticity branch with first arm lock is connected or contacts, the middle part of second elasticity branch with the second arm lock is connected or contacts, first elasticity branch the middle part can for first arm lock motion, second elasticity branch the middle part can for the second arm lock motion.

In some embodiments, the widths of the first and second spring struts vary during movement of the middle portion of the first spring strut relative to the first clamp arm and movement of the middle portion of the second spring strut relative to the second clamp arm.

In some embodiments, the middle portion of the first spring strut is connected to or in contact with an outer side of the first clamp arm; the middle part of the second elastic supporting rod is connected or contacted with the outer side of the second clamping arm.

In some embodiments, the middle portion of the first spring strut is connected to or in contact with the inner side of the first clamp arm; the middle part of the second elastic supporting rod is connected or contacted with the inner side of the second clamping arm.

In some embodiments, the middle portion of the first spring strut includes a first receiving hole through which the first clip arm passes; the middle portion of the second elastic support rod comprises a second accommodating hole, and the second clamping arm penetrates through the second accommodating hole.

In some embodiments, the first clamp arm comprises a first inner clamp arm, a first outer clamp arm, and a first bend, and the second clamp arm comprises a second inner clamp arm, a second outer clamp arm, and a second bend; the first inner clamping arm and the first outer clamping arm are connected through the first bent part, and the second inner clamping arm and the second outer clamping arm are connected through the second bent part; the middle part of the first elastic supporting rod can move between the first bending part and one end, far away from the first bending part, of the first inner clamping arm, and the middle part of the second elastic supporting rod can move between the second bending part and one end, far away from the second bending part, of the second inner clamping arm.

In some embodiments, the tissue gripping device comprises a first control line for controlling movement of the middle portion of the first resilient strut relative to the first clamp arm, and a second control line for controlling movement of the middle portion of the second resilient strut relative to the second clamp arm; one end of the first control wire is connected with the middle part of the first elastic supporting rod, and one end of the second control wire is connected with the middle part of the second elastic supporting rod; the other ends of the first control wire and the second control wire are connected with an external control handle.

In some embodiments, the first control wire and the second control wire move the first resilient strut and the second resilient strut synchronously under the control of the control handle.

In some embodiments, the tissue gripping device further comprises a first resilient member and a second resilient member; one end of the first elastic piece is connected with the first bending part, and the other end of the first elastic piece is connected with the middle part of the first elastic support rod; one end of the second elastic piece is connected with the second bending part, and the other end of the second elastic piece is connected with the middle part of the second elastic supporting rod.

In some embodiments, the tissue gripping device comprises a first screw for controlling movement of the middle portion of the first resilient strut relative to the first clamp arm, and a second screw for controlling movement of the middle portion of the second resilient strut relative to the second clamp arm; the middle part of the first elastic supporting rod is in threaded connection with the first screw rod, and the rotation of the first screw rod can drive the middle part of the first elastic supporting rod to move; the middle part of the second elastic supporting rod is in threaded connection with the second screw rod, and the rotation of the second screw rod can drive the middle part of the second elastic supporting rod to move.

In some embodiments, the tissue gripping device further comprises a first screw control line and a second screw control line; the first screw control line is in transmission connection with the first screw so as to drive the first screw to rotate; two free ends of the first screw control line are connected with an external control handle; the second screw control line is in transmission connection with the second screw so as to drive the second screw to rotate, and two free ends of the second screw control line are connected with an external control handle.

In some embodiments, the tissue gripping device further comprises a first screw control rod and a second screw control rod; the first screw rod control rod is in transmission connection with the first screw rod through a universal joint, and the rotation of the first screw rod control rod can drive the first screw rod to rotate; the second screw control rod is connected with the second screw through a universal joint in a transmission mode, and the second screw can be driven to rotate by rotation of the second screw control rod.

In some embodiments, the tissue gripping device further comprises a support, a first connector, and a second connector; one end of the supporting part is connected with the first connecting piece; one end of the first inner clamping arm, which is far away from the first bent part, and one end of the second inner clamping arm, which is far away from the second bent part, are connected with the other end of the supporting part; one end of the first outer clamping arm, one end of the second outer clamping arm, and two ends of the first elastic support rod and the second elastic support rod are connected with the second connecting piece; the first connecting piece and the second connecting piece can move relatively to drive the first inner clamping arm and the second inner clamping arm to open or close relatively.

In some embodiments, the first clamp assembly further comprises a first jaw disposed on the first inner clamp arm, the second clamp assembly further comprises a second jaw disposed on the second inner clamp arm; the first and second jaws are openable relative to the first and second inner clamp arms, respectively, and enable tissue to be clamped between the first jaw and the first inner clamp arm and between the second jaw and the second inner clamp arm.

In some embodiments, a side of the first clip facing the first inner clip arm and a side of the second clip facing the second inner clip arm are provided with a plurality of barbs; the plurality of barbs are arranged in a plurality of rows or a plurality of columns.

In some embodiments, the first inner clip arm and the second inner clip arm are provided with through holes matched with the plurality of barbs.

In some embodiments, a developing ring is disposed on the first clamping assembly or the second clamping assembly, and a mark corresponding to a position of the developing ring is disposed on a control handle of the first clamping assembly or the second clamping assembly.

In some embodiments, the elastic support is an integrally formed structure made of shape memory alloy tube material through cutting and heat treatment setting.

One of the embodiments of the present application provides a tissue repair device comprising a control handle and a tissue gripping means as described in any of the embodiments of the present application; the control handle is used for conveying the tissue clamping device to a tissue position and respectively controlling the first clamping assembly and the second clamping assembly of the tissue clamping device to clamp the tissue.

In some embodiments, a control mechanism is provided on the control handle, the control mechanism being configured to: and controlling the middle part of the first elastic supporting rod, which is connected or contacted with the first clamping arm, to move relative to the first clamping arm, and controlling the middle part of the second elastic supporting rod, which is connected or contacted with the second clamping arm, to move relative to the second clamping arm.

Drawings

The present application will be further explained by way of exemplary embodiments, which will be described in detail by way of the accompanying drawings. These embodiments are not intended to be limiting, and in these embodiments like numerals are used to indicate like structures, wherein:

FIG. 1 is a perspective view of a tissue gripping device according to some embodiments of the present application;

FIG. 2 is a front view schematic of a tissue gripping device according to some embodiments of the present application;

FIG. 3 is a schematic side view of an operational state of a tissue gripping device according to some embodiments of the present application;

FIG. 4 is a front view of a tissue gripping device according to some embodiments of the present application;

FIG. 5 is a schematic structural view of a resilient support of the tissue gripping device according to some embodiments of the present application;

FIG. 6 is a schematic view of a resilient support of a tissue gripping device according to another embodiment of the present application;

FIG. 7 is a schematic structural view of a resilient support of the tissue gripping device according to yet another embodiment of the present application;

FIG. 8 is a control schematic of the resilient support of the tissue gripping device according to some embodiments of the present application;

FIG. 9 is a control schematic of the resilient support of the tissue gripping device according to another embodiment of the present application;

FIG. 10 is an enlarged partial view of the control schematic of the resilient support of FIG. 9;

FIG. 11 is a control schematic of the resilient support of the tissue gripping device according to yet another embodiment of the present application;

FIG. 12 is an enlarged partial view of the control schematic of the resilient support of FIG. 11;

FIG. 13 is a schematic structural view of a tissue gripping device having a visualization ring according to some embodiments of the present application;

FIG. 14 is a schematic structural view of a clip with developer ring according to some embodiments of the present application;

fig. 15 is a schematic structural view of a tissue repair device according to some embodiments of the present application.

Description of reference numerals: 100-tissue clamping device, 110-clamping component, 110-1-first clamping component, 110-2-second clamping component, 111-first clamping arm, 112-second clamping arm, 1111-first inner clamping arm, 1112-first outer clamping arm, 1113-first bending part, 1121-second inner clamping arm, 1122-second outer clamping arm, 1123-second bending part, 113-first clamping piece, 114-second clamping piece, 1131-fixing part, 1132-clamping part, 115-barb, 116-through hole, 117-developing ring, 120-elastic support, 120-1-first elastic support rod, 120-2-second elastic support rod, 121-1-first accommodation hole, 121-2-second accommodation hole, 122-first mounting part, 123-a second mounting part, 124-a first connecting part, 125-a second connecting part, 126-a first bending part, 127-a second bending part, 128-a third bending part, 131-a first control wire, 132-a first screw, 133-a first screw control wire, 134-a first elastic part, 140-a supporting part, 150-a first connecting part, 160-a second connecting part, 200-a control handle, 300-a conveying pipe, 1000-a tissue repair device.

Detailed Description

In order to more clearly illustrate the technical solutions of the embodiments of the present specification, the drawings used in the description of the embodiments will be briefly described below. It is obvious that the drawings in the following description are only examples or embodiments of the present description, and that for a person skilled in the art, the present description can also be applied to other similar scenarios on the basis of these drawings without inventive effort. It is to be understood that these exemplary embodiments are given solely to enable those skilled in the relevant art to better understand and implement the present description, and are not intended to limit the scope of the present description in any way. Unless otherwise apparent from the context, or otherwise indicated, like reference numbers in the figures refer to the same structure or operation.

As used in this specification and the appended claims, the terms "a," "an," "the," and/or "the" are not intended to be inclusive in the singular, but rather are intended to be inclusive in the plural, unless the context clearly dictates otherwise. In general, the terms "comprises" and "comprising" merely indicate that steps and elements are included which are explicitly identified, that the steps and elements do not form an exclusive list, and that a method or apparatus may include other steps or elements. The term "one embodiment" means "at least one embodiment"; the term "another embodiment" means "at least one additional embodiment".

In the description of the present specification, it is to be understood that the terms "upper", "lower", "inner", "outer", "away", "near", "symmetrical", "one end", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are only for convenience in describing and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present specification.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present specification, "a plurality" means at least two, e.g., two, three, etc., unless explicitly defined otherwise.

In this specification, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integral to one another; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present specification can be understood by those of ordinary skill in the art as appropriate.

The embodiment of the application relates to a tissue clamping device and a tissue repair device. The tissue clamping device and the tissue repair equipment can realize the clamping and repair of tissues. The tissue gripping device may be suitable for a variety of applications, for example, for gripping tissue of a heart valve (e.g., mitral valve, tricuspid valve) or a vascular valve. In some embodiments, the tissue gripping device can grip and repair tissue by multiple paths to a predetermined location. For example, a tissue gripping device may be delivered to the mitral valve via the femoral vein, inferior vena cava, right atrium, and left atrium under control of the control handle to repair the mitral valve. For another example, a tissue gripping device may be delivered to the mitral valve via the left atrial appendage and the left atrium under control of a control handle to repair the mitral valve. As another example, a tissue gripping device may be delivered to the tricuspid valve via the femoral vein, inferior vena cava, and right atrium under control of a control handle to repair the tricuspid valve.

In mitral and tricuspid valve regurgitation repair procedures, the probability of difficulties in advancing and withdrawing the tissue gripping device (also referred to as a clip) is low, and once it occurs, adverse events will occur clinically, with possible serious consequences. The tissue clamping device that this application embodiment provided is variable, through with elastic support piece and arm lock swing joint for tissue clamping device can be according to advancing the sheath, catch, go out different in service conditions such as sheath and change the form, thereby can solve the clamping device and advance the sheath and withdraw the difficulty, and catch the difficult scheduling problem of leaflet.

The tissue holding device and the tissue repair device provided by the embodiments of the present application will be described in detail below with reference to the accompanying drawings.

FIG. 1 is a perspective view of a tissue gripping device according to some embodiments of the present application; FIG. 2 is a front view schematic of a tissue gripping device according to some embodiments of the present application; FIG. 3 is a schematic side view of an operational state of a tissue gripping device according to some embodiments of the present application; FIG. 4 is a front view of a tissue gripping device according to some embodiments of the present application.

In some embodiments, as shown in fig. 1-4, tissue gripping device 100 may include a gripping assembly 110 and a resilient support 120. The clamping member 110 may represent an element or an assembly having a clamping function, and the elastic support 120 may represent an element or an assembly having a certain elastic property. In some embodiments, the clamping assembly 110 and the resilient support 120 may have a deformation capability. In some embodiments, the clamping assembly 110 and/or the resilient support 120 may also have the ability to recover deformation. Clamping assembly 110 may include a first clamping assembly 110-1 and a second clamping assembly 110-2, and resilient support 120 may include a first resilient strut 120-1 and a second resilient strut 120-2. In some embodiments, first clamp assembly 110-1 and second clamp assembly 110-2 may be disposed substantially symmetrically (e.g., disposed opposite each other with the y-z plane as a plane of symmetry), and first resilient strut 120-1 and second resilient strut 120-2 may be disposed substantially symmetrically (e.g., disposed opposite each other with the y-z plane as a plane of symmetry). In this specification, "substantially symmetrical" may mean that a plane (i.e., a plane of symmetry, such as a y-z plane) exists such that a line connecting any set of two points corresponding to each other on two objects (e.g., the first and second clamping assemblies 110-1 and 110-2, and the first and second resilient struts 120-1 and 120-2) is perpendicular to the plane or at an angle of 80 ° or more (i.e., approximately perpendicular) to the plane. In the present specification, the z-axis may refer to a direction from bottom to top along a central axis of the tissue clamping device, the x-axis may refer to a direction connecting two points corresponding to each other in the first clamping member 110-1 and the second clamping member 110-2, and the y-axis is perpendicular to both the x-axis and the z-axis. In some embodiments, the first and second clamp assemblies 110-1 and 110-2 may be asymmetrically arranged; the first resilient strut 120-1 and the second resilient strut 120-2 may be asymmetrically disposed. For example, the clamping arms (e.g., first inner clamping arm, first outer clamping arm) of first clamping assembly 110-1 may be longer than the clamping arms (e.g., second inner clamping arm) of second clamping assembly 110-1, and first resilient strut 120-1 may be longer than second resilient strut 120-2.

In some embodiments, first clamping assembly 110-1 and second clamping assembly 110-2 may both be used to clamp tissue, for example, first clamping assembly 110-1 and second clamping assembly 110-2 may be used to clamp both valves of a mitral valve, respectively. In some embodiments, first clamp assembly 110-1 may include a first clamp arm 111, second clamp assembly 110-2 may include a second clamp arm 112, first clamp arm 111 and second clamp arm 112 may be configured (e.g., opened or closed) under the control of an external control handle (e.g., control handle 200) connected thereto, and the angle (or relative position) between first clamp arm 111 and second clamp arm 112 may vary depending on the configuration of first clamp assembly 110-1 and second clamp assembly 110-2. In some embodiments, the angle between the first clamping arm 111 and the second clamping arm 112 may be the angle between the first inner clamping arm 1111 and the second inner clamping arm 1121, or the angle between the first outer clamping arm 1112 and the second outer clamping arm 1122. In some embodiments, the configuration of the first and second clamp assemblies 110-1 and 110-2 may be controlled by external control handles attached thereto.

In some embodiments, a middle portion of first resilient strut 120-1 may be connected to or in contact with first clamp arm 111 and a middle portion of second resilient strut 120-2 may be connected to or in contact with second clamp arm 112. The middle portion of the first elastic strut 120-1 connected to or in contact with the first clamping arm 111 can move along the first clamping arm 111 relative to the first clamping arm 111, and the middle portion of the second elastic strut 120-2 connected to or in contact with the second clamping arm 112 can move along the second clamping arm 112 relative to the second clamping arm 112. In some embodiments, the middle portion of first resilient strut 120-1 connected to or in contact with first clamp arm 111 and the middle portion of second resilient strut 120-2 connected to or in contact with second clamp arm 112 may move in the x-z plane along first clamp arm 111 and second clamp arm 112, respectively, during opening or closing of first clamp assembly 110-1 and second clamp assembly 110-2. In some embodiments, first and second resilient struts 120-1 and 120-2 are movable relative to first and second clamp

arms

111 and 112 under the control of an external control handle connected thereto.

Reference is made to fig. 3-4, wherein fig. 3A, 3B are left side views (y-z plan views) of the tissue gripping device and fig. 4A, 4B are front views (x-z plan views) of the tissue gripping device. FIGS. 3A and 4A show a semi-expanded state of the tissue gripping device (between the expanded state and the extended state), and FIGS. 3B and 4B show an extended state of the tissue gripping device (or semi-extended state, near the extended state but not fully extended). When the tissue gripping device is in the extended state, the included angle between the connected inner and outer clamp arms (e.g., the first inner and

outer clamp arms

1111 and 1112, or the second inner and outer clamp arms 1121 and 1122) is greater than a predetermined threshold (e.g., 130 °, 150 °, etc.). As can be seen by comparing FIGS. 3A and 4A with FIGS. 3B and 4B, the widths (i.e., the dimension along the y-axis) of first and second resilient struts 120-1 and 120-2 can be varied during the movement of the middle portion of first resilient strut 120-1 connected to or in contact with first arm 111 and second arm 112, respectively, relative to first and second arm arms 111 and 112 (or during the variation of the tissue gripping device between the open and extended states shown in FIGS. 3-4), while the dimension along the x-axis of the tissue gripping device as a whole can be varied. The tissue gripping device provided by the embodiments of the present disclosure can be adjusted in its overall dimensions in the x-axis and y-axis directions under the control of the external control handle, so as to adapt to the clinical requirements of the tissue gripping device at different stages of use.

In some embodiments, during the process of capturing tissue (e.g., valve leaflets), the control handle can control the first and second clamping assemblies 110-1 and 110-2 in the tissue clamping device to be in the open state (as shown in fig. 1-2) and make the first and second elastic struts 120-1 and 120-2 in the natural deployment state, so that the first and second elastic struts 120-1 and 120-2 have a certain width in the y-axis and x-axis directions, which can increase the capture area of the tissue clamping device and facilitate capturing tissue. During the process of sheath advancing (i.e. the process of delivering the tissue holding device to the target site) and withdrawing (e.g. the process of withdrawing the tissue holding device due to failure), the first clamping assembly 110-1 and the second clamping assembly 110-2 in the tissue holding device can be controlled to be in the extended state (as shown in fig. 3B or 4B) by the control handle, and at this time, the first elastic strut 120-1 and the second elastic strut 120-2 can be further controlled to be in the closed state (as shown in fig. 3B or 4B), and the width of the whole tissue holding device in the x-axis direction and the y-axis direction can be simultaneously reduced (i.e. the cross-sectional area of the tissue holding device is reduced), so that the obstruction during the sheath advancing and withdrawing process can be reduced, and the sheath advancing and the withdrawing process can be facilitated.

In some embodiments, an external control handle may provide simultaneous control of first clamp assembly 110-1, second clamp assembly 110-2, and first resilient strut 120-1, second resilient strut 120-2. In some embodiments, an external control handle may control first clamp assembly 110-1, second clamp assembly 110-2, and first resilient strut 120-1, second resilient strut 120-2, respectively.

In some embodiments, the elastic support member may be an integrally formed structure made of a shape memory alloy tube material through cutting and heat treatment setting. The shape memory alloy may be a nickel titanium alloy or a cobalt chromium alloy, or the like. Preferably, the material of the elastic support member may be a super-elastic metal (e.g., nitinol). In some embodiments, the natural state (also referred to as a memory shape) of the resilient support may be an expanded state, a closed state, or a semi-expanded state (between the expanded state and the closed state). Wherein the unfolded state may mean that the middle of the first elastic strut 120-1 of the elastic support member is at a maximum distance state with respect to the middle of the second elastic strut 120-2, and the folded state may mean that the middle of the first elastic strut 120-1 of the elastic support member is at a minimum distance state with respect to the middle of the second elastic strut 120-2. In some embodiments, the amount of spring force provided by the first and second resilient struts 120-1, 120-2 to the tissue gripping device may be adjusted based on the tissue gripping requirements of different tissues or different patients (e.g., adjusting the width or nature of the first and/or second resilient struts 120-1, 120-2) such that the tissue gripping device employing the first and second resilient struts 120-1, 120-2 may be adapted for different tissues or different patients.

FIG. 5 is a schematic diagram of a resilient support of a tissue gripping device according to some embodiments of the present application. In some embodiments, as shown in FIG. 5, the resilient support may include a first resilient strut 120-1, a second resilient strut 120-2, a first mounting portion 122, and a second mounting portion 123. Wherein the first mounting portion 122 and the second mounting portion 123 may be fixed relative to one end of the tissue gripping device (e.g., the second connector). The two ends of the first elastic strut 120-1 are respectively connected with the first mounting part 122 and the second mounting part 123, and the middle part of the first elastic strut is in a curved arc shape; similarly, the second elastic strut 120-2 is connected at its both ends to the first mounting portion 122 and the second mounting portion 123, respectively, and has a curved arc shape at its middle portion. In some embodiments, as shown in FIG. 5, one end of the first and second resilient struts 120-1 and 120-2 may be connected to the first mounting portion 122 by a first connection 124; the other ends of the first and second resilient struts 120-1 and 120-2 may be connected to the second mounting portion 123 by a second connecting portion 125. The stability of the first and second resilient struts 120-1 and 120-2 can be improved by providing the first and second connecting

portions

124 and 125. In some embodiments, the first connection portion 124 and the second connection portion 125 may be provided with through holes. The number of the through holes may include one or more. The shape of the through hole may include, but is not limited to, a long stripe, a square, a circle, a rectangle, and the like. By providing the through holes on the first connection portion 124 and the second connection portion 125, the elastic support member (e.g., the distal end of the elastic support member) can be easily changed in shape at the time of heat treatment.

In some embodiments, a middle portion of first resilient strut 120-1 may be connected to or in contact with an outer side of first clamp arm 111 (as shown in FIG. 2). The middle portion of second spring strut 120-2 may be connected to or in contact with the outer side of second clamp arm 112. In some embodiments, the natural state of the resilient support may be the deployed state. By connecting or contacting the middle portion of the first elastic strut 120-1 to the outer side of the first clip arm 111 and connecting or contacting the middle portion of the second elastic strut 120-2 to the outer side of the second clip arm 112, the first clip arm 111 and the second clip arm 112 can enhance the stability of the tissue gripping device in capturing the leaflets under the elastic force of the elastic support.

In some embodiments, a middle portion of first resilient strut 120-1 may be connected to or in contact with an inner side of first clamp arm 111 (as shown in FIG. 1). The middle portion of second spring strut 120-2 may be connected to or in contact with the inner side of second clamp arm 112. The middle of the first elastic strut 120-1 is connected or contacted with the inner side of the first clamping arm 111, and the middle of the second elastic strut 120-2 is connected or contacted with the inner side of the second clamping arm 112, so that the first clamping arm 111 and the second clamping arm 112 can enhance the clamping force of the tissue clamping device when clamping the tissue under the elastic force of the elastic support.

FIG. 6 is a schematic view of a resilient support of a tissue gripping device according to another embodiment of the present application. In some embodiments, as shown in FIG. 6, the resilient support may include a first resilient strut 120-1, a second resilient strut 120-2, a first mounting portion 122, and a second mounting portion 123. Wherein the first mounting portion 122 and the second mounting portion 123 may be fixed relative to one end of the tissue gripping device (e.g., the second connector). The first resilient strut 120-1 is connected at both ends thereof to the first mounting portion 122 and the second mounting portion 123, respectively. In some embodiments, as shown in FIG. 6, the first resilient strut 120-1 may include a first bend 126, a second bend 127, and a third bend 128. Wherein the second bending part 127 may be located between the first bending part 126 and the third bending part 128, and the bending direction of the second bending part 127 is opposite to the first bending part 126 and the third bending part 128. Specifically, the second curved portion 127 has an inwardly curved arc shape, and the first curved portion 126 and the third curved portion 128 have an outwardly curved arc shape. In the embodiment shown in FIG. 6, the middle portion of the first resilient strut 120-1 may be the second bend 127. The second resilient strut 120-2 may have the same or similar structure as the first resilient strut 120-1 and will not be described in detail herein. It should be noted that "bending outward" herein may mean that the bending direction is opposite to the direction in which both ends of the first elastic strut 120-1 or the second elastic strut 120-2 are oriented (downward as shown in fig. 6), and "bending inward" may mean that the bending direction is the same as the direction in which both ends of the first elastic strut 120-1 or the second elastic strut 120-2 are oriented.

In some embodiments, a middle portion (e.g., second bend 127) of first resilient strut 120-1 may be connected to or in contact with an inner side of first clamp arm 111. Similarly, the middle portion of second resilient strut 120-2 may be connected to or in contact with the inner side of second clamp arm 112. In some embodiments, the default state of the elastic support may be a closed or semi-closed state, and the middle portion of the first elastic strut 120-1 is connected or contacted with the inner side of the first clamping arm 111, and the middle portion of the second elastic strut 120-2 is connected or contacted with the inner side of the second clamping arm 112, so that the first clamping arm 111 and the second clamping arm 112 can enhance the clamping force of the tissue clamping device when clamping the tissue under the elastic force of the elastic support.

FIG. 7 is a schematic diagram of a resilient support of a tissue gripping device according to yet another embodiment of the present application. In some embodiments, as shown in FIG. 7, the resilient support may include a first resilient strut 120-1, a second resilient strut 120-2, a first mounting portion 122, and a second mounting portion 123. Wherein the first mounting portion 122 and the second mounting portion 123 may be fixed relative to one end of the tissue gripping device (e.g., the second connector). The first and second elastic struts 120-1 and 120-2 are coupled at both ends thereof to the first and second mounting

parts

122 and 123, respectively. In some embodiments, as shown in FIG. 7, the middle portion of the first resilient strut 120-1 may include a first receiving hole 121-1 and the middle portion of the second resilient strut 120-2 may include a second receiving hole 121-2. The first and second receiving holes 121-1 and 121-2 may be formed of first and second bent sections bent outward and inward, respectively. In some embodiments, the first and second receiving holes 121-1 and 121-2 may be oval, oblate, circular, or other shapes. In some embodiments, the shape of the first receiving hole 121-1 and the shape of the second receiving hole 121-2 may be the same or different. It should be noted that "bending outward" herein may mean that the bending direction is opposite to the direction in which both ends of the first elastic strut 120-1 or the second elastic strut 120-2 are oriented (downward as shown in fig. 7), and "bending inward" may mean that the bending direction is the same as the direction in which both ends of the first elastic strut 120-1 or the second elastic strut 120-2 are oriented.

In some embodiments, the first clip arm 111 may pass through the first receiving hole 121-1. The second clip arm 112 may pass through the second receiving hole 121-2. In some embodiments, the shapes of the first and second receiving holes 121-1 and 121-2 may be designed according to the shapes of the first and second clamp

arms

111 and 111. In some embodiments, by passing the first and

second clip arms

111 and 112 through the first and second receiving holes 121-1 and 121-2, respectively, the first and second elastic struts 120-1 and 120-2 can be connected or contacted with the inner sides of the first and

second clip arms

111 and 112 and the outer sides of the first and

second clip arms

111 and 112, so as to effectively restrict the relative movement between the elastic struts and the clip arms, prevent the elastic struts from moving laterally, and improve the stability and reliability of the tissue clamping device.

In some embodiments, as shown in fig. 1-2, the first clamp arm 111 may include a first inner clamp arm 1111, a first outer clamp arm 1112, and a first bend 1113, and the second clamp arm 112 may include a second inner clamp arm 1121, a second outer clamp arm 1122, and a second bend 1123. The first inner clip arm 1111 and the first outer clip arm 1112 are connected by a first bent portion 1113, and the second inner clip arm 1121 and the second outer clip arm 1122 are connected by a second bent portion 1123. In some embodiments, the bending angle of the first bending part 1113 and the second bending part 1123 may be between 0-180 °. In some embodiments, the bend angle of the first bend 1113 and the second bend 1123 may be controlled by an external control handle. In this specification, the connection between the first inner clip arm 1111 and the first outer clip arm 1112 through the first bent portion 1113 and the connection between the second inner clip arm 1121 and the second outer clip arm 1122 through the second bent portion 1123 may be understood as follows: the joint of the first inner clip arm 1111 and the first outer clip arm 1112 (i.e., the first bent portion 1113) and the joint of the second inner clip arm 1121 and the second outer clip arm 1122 (i.e., the second bent portion 1123) can be bent, the included angle between the first inner clip arm 1111 and the first outer clip arm 1112 can be changed, and the included angle between the second inner clip arm 1121 and the second outer clip arm 1122 can be changed. Through the above-mentioned structural design of the first inner clamping arm 1111, the first outer clamping arm 1112, the second inner clamping arm 1121 and the second outer clamping arm 1122, the first clamping assembly 110-1 and the second clamping assembly 110-2 can realize stable clamping of tissues.

In some embodiments, the middle portion of the first resilient strut 120-1 may be connected between the first bending portion 1113 and the end of the first inner clip arm 1111 away from the first bending portion 1113, and the middle portion of the second resilient strut 120-2 may be connected between the second bending portion 1123 and the end of the second inner clip arm 1121 away from the second bending portion 1123. The middle portion of the first elastic strut 120-1 connected or in contact with the first clamping arm 111 can move between the first bending portion 1113 and the end of the first inner clamping arm 1111 away from the first bending portion 1113, and the middle portion of the second elastic strut 120-2 connected or in contact with the second clamping arm 112 can move between the second bending portion 1123 and the end of the second inner clamping arm 1121 away from the second bending portion 1123. In some embodiments, first and second resilient struts 120-1 and 120-2 are movable relative to first and second clamp

arms

111 and 112 under the control of an external control handle connected thereto.

In some embodiments, the tissue gripping device may further comprise a support 140, a first connector 150, and a second connector 160. One end (upper end as shown in fig. 1) of the supporting portion 140 is connected to the first connector 150. One end of the first inner clip arm 1111 away from the first bending portion 1113 and one end of the second inner clip arm 1121 away from the second bending portion 1123 are connected to the other end (the lower end shown in fig. 1) of the supporting portion 140 in a bendable manner. The end of the first outer clamp arm 1112 remote from the first bent portion 1113, the end of the second outer clamp arm 1122 remote from the second bent portion 1123, and the ends of the first resilient strut 120-1 and the second resilient strut 120-2 are connected to the second connector 160 (the connection means may include, but is not limited to, bonding, clipping, welding, etc.). Both ends of the first elastic strut 120-1 and the second elastic strut 120-2 may be mounted on the second connecting member 160 through the first mounting portion 122 and the second mounting portion 123, respectively. In some embodiments, the first connection member 150 and the second connection member 160 can move relatively to open or close the first inner clip arm 1111 and the second inner clip arm 1121. In some embodiments, the first inner clip arm 1111, the first bent portion 1113, the first outer clip arm 1112, the second inner clip arm 1121, the second bent portion 1123, and the second outer clip arm 1122 may be integrally formed with the support portion. In this specification, the bendable connection between the support portion 140 and the first inner clip arm 1111 and the second inner clip arm 1121 can be understood as follows: the connection between the first inner clip arm 1111 and the support portion 140 and the connection between the second inner clip arm 1121 and the support portion 140 may be bent, so that the first inner clip arm 1111 and the second inner clip arm 1121 may be bent toward the support portion to be relatively folded, or the first inner clip arm 1111 and the second inner clip arm 1121 may be bent away from the support portion to be relatively unfolded.

In some embodiments, the first link 150 and the second link 160 may be connected by a driving rod (not shown). The driving rod may be detachably connected to the second link 160 after passing through the first link 150 and the supporting portion 140. The driving rod may drive the second link 160 to move relative to the first link 150 (or the supporting portion). When the second connecting member 160 is away from the supporting portion 140, the first outer clamping arm 1112 and the second outer clamping arm 1122 can pull the first inner clamping arm 1111 and the second inner clamping arm 1121 to be opened relatively under the driving of the second connecting member 160; when the second connecting member 160 approaches the supporting portion 140, the first outer clip arm 1112 and the second outer clip arm 1122 can pull the first inner clip arm 1111 and the second inner clip arm 1121 respectively to close together under the driving of the second connecting member 160.

In some embodiments, the cross-sectional shape of the supporting part 140 may be circular or elliptical, and the cross-sectional area of the middle part of the supporting part 140 may be larger than the cross-sectional areas of both ends thereof. By such a design, possible benefits include, but are not limited to: so that the supporting part 140 does not easily damage the tissue; can form effective support for the clamped tissue. In some embodiments, the supporting portion 140 may also be a relatively rounded shape such as a cylinder. Those skilled in the art can determine the shape of the support portion 140 to be different according to the specific situation of the tissue to be clamped (such as the shape of the coaptation edge of the mitral valve leaflet), so that the shape of the support portion 140 fits the shape of the tissue (such as the coaptation edge of the mitral valve leaflet) better, and the clamping effect is better. In some embodiments, the support 140 may be a mesh structure. The supporting portion 140 of the mesh structure can effectively fill the space between the first inner clamp arm 1111 and the second inner clamp arm 1121, and can prevent the formation of thrombus after the tissue clamping device clamps the tissue (e.g., mitral valve, tricuspid valve).

In some embodiments, the first clamping assembly 110-1 may further include a first jaw 113 disposed on the first inner clamping arm 1111, and the second clamping assembly 110-2 may further include a second jaw 114 disposed on the second inner clamping arm 1121, wherein the first jaw 113 and the second jaw 114 may open and close with respect to the first inner clamping arm 1111 and the second inner clamping arm 1121, respectively, and enable tissue to be clamped between the first jaw 113 and the first inner clamping arm 1111 and between the second jaw 114 and the second inner clamping arm 1121.

In some embodiments, the first jaw 113 and the second jaw 114 can be connected to an external control handle (e.g., via a control line), and the control handle can control the opening and closing of the first jaw 113 with respect to the first inner arm 1111 and the opening and closing of the second jaw 114 with respect to the second inner arm 1121. In some embodiments, the external control handle may control the first jaw 113 and the second jaw 114, respectively. In some embodiments, each of the first clip 113 and the second clip 114 may include a fixing portion 1131 and a clamping portion 1132, and the fixing portion 1131 and the clamping portion 1132 may be connected to each other in a bendable manner. The fixing portion 1131 can be used to fix the clips (e.g., the first clip 113 and the second clip 114) to the inner clip arms (e.g., the first inner clip arm 1111 and the second inner clip arm 1121), and the clamping portion 1132 can be bent relative to the fixing portion 1131, so that the clips can open and close relative to the inner clip arms (e.g., the first inner clip arm 1111 and the second inner clip arm 1121). When the clamping portion 1132 is bent with respect to the fixing portion 1131, tissue can be clamped. It should be noted that, in the embodiment of the present application, the connection manner between the fixing portion 1131 and the inner clip arm (e.g., the first inner clip arm 1111 and the second inner clip arm 1121) may include, but is not limited to, bonding, clipping, welding, and the like.

In some embodiments, as shown in fig. 1, a side of the first jaw 113 facing the first inner jaw 1111 and a side of the second jaw 114 facing the second inner jaw 1121 may further include a plurality of barbs 115. Specifically, one end of the clamping portion 1132 may be connected to the fixing portion 1131 by a bending portion, and the plurality of barbs 115 may be disposed on the other end of the clamping portion 1132 which is not connected to the fixing portion 1131. In some embodiments, the plurality of barbs 115 may be arranged in multiple rows or columns to effectively prevent tissue from escaping between the jaws and the inner clamp arm, thereby providing a more stable tissue gripping device.

In some embodiments, as shown in FIG. 1, the first inner clip arm 1111 and the second inner clip arm 1121 can be provided with through holes 116 that cooperate with the plurality of barbs 115 to further prevent tissue from escaping between the clip and the inner clip arm, thereby providing a more stable grip of the tissue gripping device on the tissue. In some embodiments, the shape and size of the through-hole 116 matching with the plurality of barbs 115 may be designed according to the shape and size of the barbs 115, and the positions correspond to the barbs 115 one by one.

It should be noted that the above description of the number and arrangement of the barbs 115 and the through holes is only an example, in the embodiment of the present application, the design of the barbs 115 on the first jaw 113 and the second jaw 114 and the through holes on the second inner jaw 1121 and the second inner jaw 1121 may include, but is not limited to, the foregoing cases, and those skilled in the art may make corresponding changes, modifications or improvements according to the actual situations or needs, and such changes, modifications or improvements still fall within the spirit and scope of the exemplary embodiments of the present application.

FIG. 8 is a control schematic of the resilient support of the tissue gripping device according to some embodiments of the present application; FIG. 9 is a control schematic of the resilient support of the tissue gripping device according to another embodiment of the present application; FIG. 10 is an enlarged partial view of the control schematic of the resilient support of FIG. 9; FIG. 11 is a control schematic of the resilient support of the tissue gripping device according to yet another embodiment of the present application; FIG. 12 is an enlarged partial view of the control schematic of the resilient support of FIG. 11; FIG. 13 is a schematic structural view of a tissue gripping device having a visualization ring according to some embodiments of the present application. The manner in which the first resilient strut 120-1 and the second resilient strut 120-2 of the tissue gripping device provided by some embodiments of the present application are controlled is described below in conjunction with figures 8-13.

In some embodiments, as shown in FIG. 8, the tissue gripping device may include a first control line 131 for controlling the movement of the middle portion of the first resilient strut 120-1 connected to or in contact with the first clamp arm 111 relative to the first clamp arm 111, and a second control line (corresponding to the first control line 131, not shown) for controlling the movement of the middle portion of the second resilient strut 120-2 connected to or in contact with the second clamp arm 112 relative to the second clamp arm 112. Wherein, one end of the first control wire 131 is connected to the middle of the first elastic strut 120-1, one end of the second control wire is connected to the middle of the second elastic strut 120-2, and the other ends of the first control wire 131 and the second control wire can pass through the supporting part 140 to be connected with an external control handle.

In some embodiments, the middle portion of the first elastic strut 120-1 may be provided with a control hole through which the first control wire 131 may pass to connect with the middle portion of the first elastic strut 120-1. In some embodiments, the middle portion of the first elastic strut 120-1 may be provided with a groove, and the first control wire 131 may be engaged in the groove to connect with the middle portion of the first elastic strut 120-1. The connection of the first control wire 131 to the middle portion of the first elastic strut 120-1 can be conveniently achieved by providing a control hole or a groove. In some embodiments, the first control wire 131 may include two strands, one end of which may be connected to the first elastic strut 120-1 at two positions symmetrical with respect to the first clamp arm 111, and the other end of which may be connected together to an external control handle. Through the design, the first elastic strut 120-1 can be evenly stressed under the action of the first control wire 131. The second resilient strut 120-2 may have the same or similar control means and will not be described in detail herein.

In some embodiments, the first control wire 131 and the second control wire may be flexible wires, and the natural state of the first elastic strut 120-1 and the second elastic strut 120-2 may be relatively open. In some embodiments, the first resilient strut 120-1 and the second resilient strut 120-2 may be folded together under the action of the first control wire 131 and the second control wire, and then return to their relatively expanded state by returning to their resilient action after the force of the first control wire 131 and the second control wire is removed.

In some embodiments, to facilitate handling and to allow the first and second resilient struts 120-1 and 120-2 to be balanced, the other ends of the first and second control wires 131 and 120-2 may be connected together such that the first and second resilient struts 120-1 and 120-2 may move synchronously under the control of the first and

second control wires

131 and 131. In some embodiments, the movement of first resilient strut 120-1 and second resilient strut 120-2 relative to first inner clamp arm 1111 and second inner clamp arm 1121, respectively, may be controlled simultaneously during the control of the opening and closing of the tissue gripping device by the control handle.

In some embodiments, as shown in fig. 9-10, the tissue gripping device may further include a first resilient member 134 and a second resilient member (corresponding to the first resilient member 134, not shown). One end of the first elastic member 134 may be connected to the first bent portion 1113, and the other end of the first elastic member 134 may be connected to the middle portion of the first elastic strut 120-1. One end of the second elastic member may be connected to the second bent portion 1123, and the other end of the second elastic member may be connected to the middle portion of the second elastic strut 120-2. In some embodiments, the first elastic member and the second elastic member may be members having elasticity, such as springs, elastic bands, and the like. In some embodiments, the connection between the first elastic member 134 and the first bending portion 1113 and the first elastic strut 120-1 (or between the second elastic member and the second bending portion 1123 and the second elastic strut 120-2) may include, but is not limited to, bonding, clipping, welding, etc. In some embodiments, given the limited ability of first and second resilient struts 120-1, 120-2 to return to shape, the provision of first and second resilient members may assist in the return of first and second resilient struts 120-1, 120-2, thereby ensuring that first and second resilient struts 120-1, 120-2 are better able to maintain/return to an expanded state with first and second clamp assemblies 110-1, 110-2 when not acted upon by first and

second control wires

131, 131.

In some embodiments, as shown in figures 11-12, the tissue gripping device can include a first screw 132 for controlling movement of the middle portion of the first resilient strut 120-1 relative to the first clamp arm 111, and a second screw (corresponding to the first screw 132 and not shown) for controlling movement of the middle portion of the second resilient strut 120-2 relative to the second clamp arm 112. In some embodiments, the first screw 132 and the second screw may be attached to the inside or outside of the first inner clip arm 1111 and the second inner clip arm 1121, respectively. The middle portion of the first elastic strut 120-1 can be connected to the first screw 132 by a thread, and the rotation of the first screw 132 can drive the middle portion of the first elastic strut 120-1 to move relative to the first clamping arm 111. Similarly, the middle portion of the second elastic strut 120-2 can be connected to a second screw, and the rotation of the second screw can drive the middle portion of the second elastic strut 120-2 to move relative to the second clamping arm 112. In some embodiments, the connection manner of the first screw and the second screw to the first inner clip arm 1111 and the second inner clip arm 1121 respectively can include, but is not limited to, bonding, snapping, adhering, and the like. The movement control of the middle parts of the first elastic supporting rod 120-1 and the second elastic supporting rod 120-2 is realized through the screw rods, so that the control is more accurate. In some embodiments, the inner side and the outer side of the first inner clip arm 1111 may be provided with a first screw; the inner side and the outer side of the second inner clip arm 1121 may be provided with second screws.

In some embodiments, as shown in fig. 11-12, the tissue gripping device may further comprise a first screw control line 133 and a second screw control line (not shown). The first screw control line 133 may be in transmission connection with the first screw 132 to drive the first screw 132 to rotate, and two free ends of the first screw control line 133 may be connected with an external control handle. The first screw 132 can rotate under the control of the control handle, and then the middle portion of the first elastic strut 120-1 is driven to move relative to the first clamping arm 111. Similarly, the second screw control line can be in transmission connection with the second screw to drive the second screw to rotate, and two free ends of the second screw control line can be connected with an external control handle. The second screw rod can rotate under the control of the control handle, and then drives one end of the second elastic support rod 120-2 connected or contacted with the second clamping arm 112 to move relative to the second clamping arm 112.

In some embodiments, the tissue gripping device may include a first screw control rod and a second screw control rod (not shown in the figures). The first screw control rod and the first screw can be in transmission connection through a universal joint, and the rotation of the first screw control rod can drive the first screw to rotate, so that the middle part of the first elastic support rod 120-1 is driven to move relative to the first clamping arm 111. Similarly, the second screw control rod and the second screw may also be connected through a universal joint, and the rotation of the second screw control rod can drive the second screw to rotate, so as to drive the middle portion of the second elastic support rod 120-2 to move relative to the second clamping arm 112. In some embodiments, the first screw control lever and the second screw control lever may be connected to an external control handle and rotated under the control of the control handle.

FIG. 13 is a schematic structural view of a tissue gripping device having a visualization ring according to some embodiments of the present application; FIG. 14 is a schematic diagram of a clip with a developer ring according to some embodiments of the present application.

In some embodiments, a developer ring 117 may be disposed on the first gripper assembly 110-1 or the second gripper assembly 110-2. An imaging ring is understood to be a component that can be used to display images of blood vessels under ultrasound and Digital Subtraction Angiography (DSA) techniques. During surgery, images of the body vessel may be displayed by means of ultrasound and Digital Subtraction Angiography (DSA) techniques to indicate the position of the tissue holding device within the body. However, in the image, it is generally difficult for the operator to distinguish the first clamping assembly 110-1 and the second clamping assembly 110-2 of the tissue clamping device, and when the control handle controls the first clamping assembly 110-1 and the second clamping assembly 110-2 respectively, it is difficult to operate the control handle quickly and accurately to control the corresponding clamping assembly to perform the clamping operation. The first clamping assembly 110-1 and the second clamping assembly 110-2 can be distinguished by an operator through the developing ring arranged on the first clamping assembly 110-1 or the second clamping assembly 110-2.

In some embodiments, the developer ring 117 may be disposed on the first inner clamp arm 1111 or the second inner clamp arm 1121. For example, as shown in fig. 13, the developing ring 117 may be provided on the first inner clamp arm 1111. By providing the developing ring, the operator can clearly and clearly distinguish the first inner clip arm 1111 and the second inner clip arm 1121 on the image. In some embodiments, the developing ring may be simultaneously disposed on the first inner clamp arm 1111 and the second inner clamp arm 1121. When the developing rings are disposed on both the first inner clip arm 1111 and the second inner clip arm 1121, the shape of the developing ring disposed on the first inner clip arm 1111 and the developing ring disposed on the second inner clip arm 1121 and/or the position of the relative support portion 140 may be different, so as to distinguish the first inner clip arm 1111 and the second inner clip arm 1121. For example, the developing ring provided on the first inner clamp arm 1111 may have a circular shape, and the developing ring provided on the second inner clamp arm 1121 may have a triangular or rectangular shape. For another example, the developing ring disposed on the first inner clip arm 1111 is relatively close to the connection point between the first inner clip arm 1111 and the supporting portion 140, and the developing ring disposed on the second inner clip arm 1121 is relatively far from the connection point between the second inner clip arm 1121 and the supporting portion 140.

In some embodiments, a developer ring 117 may be disposed on the first clip 113 or the second clip 114. For example, as shown in fig. 13, a developing ring 117 may be provided on the first jaw 113. By providing a developer ring on the clip, the operator can clearly and clearly distinguish the first clip 113 from the second clip 114, and thus the first clamping assembly 110-1 from the second clamping assembly 110-2, on the image. In some other embodiments, a developer ring may be provided on both the first jaw 113 and the second jaw 114. When the developing rings are disposed on the first clip 113 and the second clip 114, the developing rings disposed on the first clip 113 and the second clip 114 may have different shapes and/or positions relative to the supporting portion 140, so as to distinguish the first clip 113 and the second clip 114. For example, the developing ring provided on the first jaw 113 may have a circular shape, and the developing ring provided on the second jaw 114 may have a triangular or rectangular shape. For another example, the developing ring disposed on the first clamping piece 113 is relatively close to the connection between the first clamping assembly 110-1 and the supporting portion 140, and the developing ring disposed on the second clamping piece 114 is relatively far from the connection between the second clamping assembly 110-2 and the supporting portion 140.

In some embodiments, a developer ring 117 may be disposed on both the inner clamp arm and the clip to further improve the discrimination between the first clamp assembly 110-1 and the second clamp assembly 110-2. For example, the developing ring may be provided on each of the first inner clip arm 1111 and the first clip tab 113. In some embodiments, the developer ring may include a developer wire wound around the inner clip arm and/or clip. The two ends of the developing wire can be fixed on the inner clamping arm and/or the clamping piece through welding, bonding or the like, so that the developing wire is stably arranged on the inner clamping arm and/or the clamping piece. In other embodiments, the developer ring includes a developer sheet secured to the inner clip arm and/or the clip. The developer sheet can be attached to the inner clip arm and/or clip by welding, adhesive, snap-fit, etc. In some embodiments, the developing wire and the developing sheet may be made of platinum-iridium alloy, platinum-tungsten alloy, tantalum, or the like. In some embodiments, the developer ring may also be disposed on other portions of the first and second clamp assemblies 110-1 and 110-2 (e.g., the outer clamp arms).

In some embodiments, to facilitate operator differentiation, markings corresponding to the location of the developer ring may be provided on the control handles of the first and second gripper assemblies 110-1 and 110-2. For example, when the developing ring is disposed on the first grip assembly 110-1, a mark may be provided on the control handle at a position corresponding to a control mechanism (e.g., a first control mechanism) of the first jaw 113. For another example, when the developer ring is disposed on the second clamping assembly 110-2, a mark may be provided on the control handle at a position corresponding to a control mechanism (e.g., a second control mechanism) of the second jaw 114.

The embodiment of the present application further provides a tissue repair device 1000, which comprises a control handle 200 and a tissue holding device according to any one of the above technical solutions; control handle 200 may be used to deliver the tissue gripping device to the tissue site and control the gripping of the tissue by first and second gripping assemblies 110-1 and 110-2, respectively, of the tissue gripping device. In some embodiments, the tissue repair apparatus 1000 may include a delivery tube 300, and the first connector 150 of the tissue gripping device is connected to the control handle 200 via the delivery tube 300.

In some embodiments, control handle 200 may include a first control mechanism that may be used to control first clamping assembly 110-1 (e.g., first jaw 113) to clamp tissue and a second control mechanism that may be used to control second clamping assembly 110-2 (e.g., second jaw 114) to clamp tissue; the first control mechanism and/or the second control mechanism are/is provided with distinguishing marks. The distinguishing mark may be understood as a mark that enables an operator to quickly distinguish between the first control mechanism and the second control mechanism. For example, the first control mechanism may be provided with a protrusion structure, a groove structure, or other structures that enable an operator to distinguish the first control mechanism from the second control mechanism as the distinguishing mark. For another example, the first control mechanism may be provided with a logo character "left", and the second control mechanism may be provided with a logo character "right".

In some embodiments, the tissue repair device may include a driving rod (not shown), which may be detachably connected to the second link 160 after passing through the first link 150 and the supporting portion 140. The first connector 150 may be connected to one end of the support 140, and one end of the first outer clamp arm 1112 and one end of the second outer clamp arm 1122 are connected to the second connector 160, respectively. The driving rod may drive the second link 160 to move relative to the first link 150 (or the supporting portion 140). When the second connecting member 160 is away from the supporting portion 140, the first outer clamping arm 1112 and the second outer clamping arm 1122 can pull the first inner clamping arm 1111 and the second inner clamping arm 1121 to be opened relatively under the driving of the second connecting member 160; when the second connecting member 160 approaches the supporting portion 140, the first outer clip arm 1112 and the second outer clip arm 1122 can pull the first inner clip arm 1111 and the second inner clip arm 1121 respectively to close together under the driving of the second connecting member 160.

In some embodiments, the first control mechanism and the second control mechanism may each include a pull cable, and an end of the pull cable of the first control mechanism may be connected to the free end of the first jaw 113, and an end of the pull cable of the second control mechanism may be connected to the free end of the second jaw 114. By loosening and tightening the pulling cable, the opening and closing of the first jaw 113 with respect to the first inner jaw 1111 and the opening and closing of the second jaw 114 with respect to the second inner jaw 1121 can be controlled.

In some embodiments, the control handle 200 may include a housing that may be removably coupled to the delivery tube 300. The first control mechanism and the second control mechanism may each include a sliding portion that is slidably provided on the housing. The other end of the traction cable of the first control mechanism is connected with the sliding part thereof, and the other end of the traction cable of the second control mechanism is connected with the sliding part thereof. By moving the slide relative to the housing, the pull cable can be loosened and tightened to effect opening and closing of the jaws (e.g., first jaw 113 and second jaw 114) relative to the inner clamp arms (e.g., first inner clamp arm 1111 and second inner clamp arm 1121). It is understood that the first control mechanism and the second control mechanism may have other various structures, and the present application is not limited thereto.

In some embodiments, control handle 200 may further include a control mechanism (also referred to as a third control mechanism) thereon for controlling the movement of first and second resilient struts 120-1 and 120-2 relative to first and second clamp

arms

111 and 112, respectively. In some embodiments, the control mechanism may be coupled to the first resilient strut 120-1 and the second resilient strut 120-2 via a first control wire 131 and a second control wire, respectively. In some embodiments, the control mechanism can control the movement of the middle portion of first elastic strut 120-1 relative to first clamp arm 111 and the movement of the middle portion of second elastic strut 120-2 relative to second clamp arm 112 via the first control line 131 and second control line. In some embodiments, the control mechanism can control the movement of the middle portion of the first resilient strut 120-1 relative to the first clamp arm 111 and the movement of the middle portion of the second resilient strut 120-2 relative to the second clamp arm 112 by controlling the rotation of the first and second screws.

Having thus described the basic concept, it will be apparent to those skilled in the art that the foregoing detailed disclosure is to be considered merely illustrative and not restrictive of the broad application. Various modifications, improvements and adaptations to the present application may occur to those skilled in the art, although not explicitly described herein. Such modifications, improvements and adaptations are proposed in the present application and thus fall within the spirit and scope of the exemplary embodiments of the present application.

Also, this application uses specific language to describe embodiments of the application. Reference throughout this specification to "one embodiment," "an embodiment," and/or "some embodiments" means that a particular feature, structure, or characteristic described in connection with at least one embodiment of the present application is included in at least one embodiment of the present application. Therefore, it is emphasized and should be appreciated that two or more references to "an embodiment" or "one embodiment" or "an alternative embodiment" in various places throughout this specification are not necessarily all referring to the same embodiment. Furthermore, some features, structures, or characteristics of one or more embodiments of the present application may be combined as appropriate.

Similarly, it should be noted that in the preceding description of embodiments of the application, various features are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure aiding in the understanding of one or more of the embodiments. This method of disclosure, however, is not intended to require more features than are expressly recited in the claims. Indeed, the embodiments may be characterized as having less than all of the features of a single embodiment disclosed above.

Numerals describing the number of components, attributes, etc. are used in some embodiments, it being understood that such numerals used in the description of the embodiments are modified in some instances by the use of the modifier "substantially", "approximately" or "substantially". Unless otherwise indicated, "substantially", "approximately" or "substantially" indicates that the number allows a variation of ± 10%. Accordingly, in some embodiments, the numerical parameters used in the specification and claims are approximations that may vary depending upon the desired properties of the individual embodiments. In some embodiments, the numerical parameter should take into account the specified significant digits and employ a general digit preserving approach. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the range are approximations, in the specific examples, such numerical values are set forth as precisely as possible within the scope of the application.

Finally, it should be understood that the embodiments described herein are merely illustrative of the principles of the embodiments of the present application. Other variations are also possible within the scope of the present application. Thus, by way of example, and not limitation, alternative configurations of the embodiments of the present application can be viewed as being consistent with the teachings of the present application. Accordingly, the embodiments of the present application are not limited to only those embodiments explicitly described and depicted herein.

Claims

1. A tissue clamping device is characterized by comprising a clamping component and an elastic supporting component; wherein the content of the first and second substances,

the clamping assembly comprises a first clamping assembly and a second clamping assembly, and the first clamping assembly and the second clamping assembly are used for clamping tissues; the first clamping assembly comprises a first clamping arm, and the second clamping assembly comprises a second clamping arm;

the elastic supporting piece comprises a first elastic supporting rod and a second elastic supporting rod; the middle part of first elasticity branch with first arm lock is connected or contacts, the middle part of second elasticity branch with the second arm lock is connected or contacts, first elasticity branch the middle part can for first arm lock motion, second elasticity branch the middle part can for the second arm lock motion.

2. The tissue clamping device of claim 1 wherein the widths of said first and second spring struts vary during movement of said middle portion of said first spring strut relative to said first clamp arm and movement of said middle portion of said second spring strut relative to said second clamp arm.

3. The tissue clamping device of claim 1 wherein said middle portion of said first resilient strut is connected to or in contact with an outer side of said first clamp arm; the middle part of the second elastic supporting rod is connected or contacted with the outer side of the second clamping arm.

4. The tissue gripping device of claim 1, wherein the middle portion of the first resilient strut is connected to or in contact with an inner side of the first clip arm; the middle part of the second elastic supporting rod is connected or contacted with the inner side of the second clamping arm.

5. The tissue clamping device of claim 1 wherein said middle portion of said first spring strut includes a first receiving aperture through which said first clip arm extends; the middle portion of the second elastic support rod comprises a second accommodating hole, and the second clamping arm penetrates through the second accommodating hole.

6. The tissue clamping device of claim 1, wherein said first clamping arm comprises a first inner clamping arm, a first outer clamping arm, and a first bend, and said second clamping arm comprises a second inner clamping arm, a second outer clamping arm, and a second bend;

the first inner clamping arm and the first outer clamping arm are connected through the first bent part, and the second inner clamping arm and the second outer clamping arm are connected through the second bent part;

the middle part of the first elastic supporting rod can move between the first bending part and one end, far away from the first bending part, of the first inner clamping arm, and the middle part of the second elastic supporting rod can move between the second bending part and one end, far away from the second bending part, of the second inner clamping arm.

7. The tissue clamping device of claim 6, wherein said tissue clamping device includes a first control line for controlling movement of said middle portion of said first resilient strut relative to said first clamping arm, and a second control line for controlling movement of said middle portion of said second resilient strut relative to said second clamping arm;

one end of the first control wire is connected with the middle part of the first elastic supporting rod, and one end of the second control wire is connected with the middle part of the second elastic supporting rod; the other ends of the first control wire and the second control wire are connected with an external control handle.

8. The tissue gripping device of claim 7, wherein the first control wire and the second control wire move the first resilient strut and the second resilient strut in unison under the control of the control handle.

9. The tissue gripping device of claim 7, further comprising a first resilient member and a second resilient member;

one end of the first elastic piece is connected with the first bending part, and the other end of the first elastic piece is connected with the middle part of the first elastic support rod; one end of the second elastic piece is connected with the second bending part, and the other end of the second elastic piece is connected with the middle part of the second elastic supporting rod.

10. The tissue gripping device of claim 6, wherein the tissue gripping device includes a first screw for controlling movement of the middle portion of the first resilient strut relative to the first clamp arm, and a second screw for controlling movement of the middle portion of the second resilient strut relative to the second clamp arm;

the middle part of the first elastic supporting rod is in threaded connection with the first screw rod, and the rotation of the first screw rod can drive the middle part of the first elastic supporting rod to move;

the middle part of the second elastic supporting rod is in threaded connection with the second screw rod, and the rotation of the second screw rod can drive the middle part of the second elastic supporting rod to move.

11. The tissue gripping device of claim 10, further comprising a first screw control line and a second screw control line;

the first screw control line is in transmission connection with the first screw so as to drive the first screw to rotate; two free ends of the first screw control line are connected with an external control handle;

the second screw control line is in transmission connection with the second screw so as to drive the second screw to rotate, and two free ends of the second screw control line are connected with an external control handle.

12. The tissue gripping device of claim 10, further comprising a first screw control rod and a second screw control rod;

the first screw rod control rod is in transmission connection with the first screw rod through a universal joint, and the rotation of the first screw rod control rod can drive the first screw rod to rotate;

the second screw control rod is connected with the second screw through a universal joint in a transmission mode, and the second screw can be driven to rotate by rotation of the second screw control rod.

13. The tissue gripping device of claim 6, further comprising a support, a first connector, and a second connector;

one end of the supporting part is connected with the first connecting piece;

one end of the first inner clamping arm, which is far away from the first bent part, and one end of the second inner clamping arm, which is far away from the second bent part, are connected with the other end of the supporting part;

one end of the first outer clamping arm, one end of the second outer clamping arm, and two ends of the first elastic support rod and the second elastic support rod are connected with the second connecting piece;

the first connecting piece and the second connecting piece can move relatively to drive the first inner clamping arm and the second inner clamping arm to open or close relatively.

14. The tissue gripping device of claim 6, wherein the first gripping assembly further comprises a first jaw disposed on the first inner jaw arm, and the second gripping assembly further comprises a second jaw disposed on the second inner jaw arm; the first and second jaws are openable relative to the first and second inner clamp arms, respectively, and enable tissue to be clamped between the first jaw and the first inner clamp arm and between the second jaw and the second inner clamp arm.

15. The tissue gripping device of claim 14, wherein a side of the first jaw facing the first inner clip arm and a side of the second jaw facing the second inner clip arm are provided with a plurality of barbs; the plurality of barbs are arranged in a plurality of rows or a plurality of columns.

16. The tissue gripping device of claim 15, wherein the first inner jaw arm and the second inner jaw arm are provided with through holes for mating with the plurality of barbs.

17. The tissue gripping apparatus of claim 1, wherein the first or second gripping assembly has a visualization ring disposed thereon, and wherein the control handle of the first or second gripping assembly has indicia corresponding to the location of the visualization ring.

18. The tissue gripping apparatus of claim 1, wherein the resilient support is a one-piece structure of shape memory alloy tubing cut and heat set.

19. A tissue repair device comprising a control handle and a tissue gripping means according to any one of claims 1 to 18; the control handle is used for conveying the tissue clamping device to a tissue position and respectively controlling the first clamping assembly and the second clamping assembly of the tissue clamping device to clamp the tissue.

20. The tissue repair device of claim 19 wherein the control handle has a control mechanism thereon for: and controlling the middle part of the first elastic supporting rod, which is connected or contacted with the first clamping arm, to move relative to the first clamping arm, and controlling the middle part of the second elastic supporting rod, which is connected or contacted with the second clamping arm, to move relative to the second clamping arm.