CN216063644U - Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling - Google Patents

Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling Download PDF

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Publication number
CN216063644U
CN216063644U CN202121980421.7U CN202121980421U CN216063644U CN 216063644 U CN216063644 U CN 216063644U CN 202121980421 U CN202121980421 U CN 202121980421U CN 216063644 U CN216063644 U CN 216063644U
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China
Prior art keywords
case
cooling
cooling groove
water circulation
ultrasonic cell
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CN202121980421.7U
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Chinese (zh)
Inventor
吴盛逵
阮金祥
余俊耀
廖铀
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Shanghai Zhenhao Electronic Technology Co ltd
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Shanghai Zhenhao Electronic Technology Co ltd
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Abstract

The utility model discloses an integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling, which comprises a case, wherein a transducer is arranged on the top surface of the case, a knob switch, a transducer socket and a temperature detection socket are arranged on the upper part of the back surface of the case, a power switch, a fuse and a power socket are arranged on the lower part of the back surface of the case, a display panel and a touch screen are arranged on the upper part of the front surface of the case, a working cavity and a case door are arranged on the lower part of the case, a cooling groove is arranged in the working cavity, a temperature control probe and an amplitude transformer are arranged above the cooling groove, an LED illuminating lamp is arranged on the left side of the cooling groove, an opening is arranged on the upper surface of the cooling groove, a plurality of clamping slide blocks are arranged on the outer side of the opening, the clamping slide blocks are all slidably mounted on the upper surface of the cooling groove through mounting slide grooves, fastening bolts are all slidably connected on the clamping slide blocks in a penetrating mode, and the lower ends of the fastening bolts are all in threaded connection with the upper surface of the cooling groove. The utility model is convenient for installing and fixing the test tube, immediately breaks the cell after reaching the temperature control requirement and has high working efficiency.

Description

Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling
Technical Field
The utility model relates to the technical field of cell disruption, in particular to an integrated ultrasonic cell disruption machine capable of controlling temperature through water circulation cooling.
Background
The ultrasonic cell disruptor converts electric energy into sound energy through a transducer, the energy is changed into dense small bubbles through a liquid medium, the small bubbles are rapidly burst to generate energy like small bombs, and therefore the effect of disrupting substances such as cells is achieved.
Ultrasonic wave cell disruption machine on the existing market all is the components of a whole that can function independently structure basically, and the test solution that needs to break the cell through ultrasonic wave generally all has the temperature requirement, and the researcher generally will be equipped with the test tube of biological agent and place the cooling in the piece of broken ice, can test after reaching the temperature requirement, and is very inconvenient, and efficiency is very low, has certain defect.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide an integrated ultrasonic cell crusher for controlling temperature through water circulation cooling, so that a test tube filled with a biological agent is placed in a circulation cooling water tank and fixed, cell crushing is carried out immediately after temperature control requirements are met, and the working efficiency is high.
In order to solve the technical problems, the utility model provides an integrated ultrasonic cell crusher for cooling and controlling temperature through water circulation, which comprises a case, wherein the top surface of the case is provided with a transducer, the upper part of the back surface of the case is provided with a knob switch, a transducer socket and a temperature detection socket, the lower part of the back surface of the case is provided with a power switch, a fuse and a power socket, the upper part of the front surface of the case is provided with a display panel and a touch screen, the lower part of the case is provided with a working cavity and a case door, the inside of the working cavity is provided with a cooling groove, a temperature control probe and an amplitude transformer are arranged above the cooling groove, the left side of the cooling groove is provided with an LED illuminating lamp, the upper surface of the cooling groove is provided with an opening, the outer side of the opening is provided with a plurality of clamping slide blocks, the clamping slide blocks are all slidably mounted on the upper surface of the cooling groove through mounting slide grooves, and fastening bolts are all slidably connected on the clamping slide blocks, the lower ends of the fastening bolts are in threaded connection with the upper surface of the cooling tank.
Furthermore, the clamping slide block is provided with non-slip pads at one end close to the opening, and the non-slip pads are all arc-shaped.
Further, cooling tank bottom fixedly connected with cooling tank tray, cooling tank tray bottom symmetry is equipped with the flexible loop bar of a plurality of, just the equal fixed mounting of flexible loop bar lower extreme is in on the quick-witted incasement bottom surface, cooling tank tray bottom transmission is connected with electric putter, electric putter lower extreme fixed mounting be in quick-witted bottom of the case portion.
Furthermore, a heat dissipation fan and a plurality of heat dissipation holes are arranged on the back of the case.
Compared with the prior art, the utility model at least has the following beneficial effects:
according to the utility model, the test tube in the cooling groove is clamped and positioned by the clamping slide block, the cooling groove simultaneously cools the cells in the test tube, and the cells can be crushed when the cells are cooled to a preset temperature without transferring the test tube, so that the efficiency and effect of cell crushing treatment are improved.
Drawings
FIG. 1 is a front view of the external structure of the integrated ultrasonic cell crusher for controlling temperature by water circulation cooling according to the present invention;
FIG. 2 is a rear view of the external structure of the integrated ultrasonic cell crusher for controlling temperature by water circulation cooling according to the present invention;
FIG. 3 is a schematic view of the cooling tank installation structure of the integrated ultrasonic cell crusher for cooling and controlling temperature by water circulation according to the present invention;
FIG. 4 is a top view of the external structure of the cooling tank of the integrated ultrasonic cell crusher for cooling and controlling temperature by water circulation according to the present invention.
Detailed Description
The integrated ultrasonic cell disruptor with temperature control by water-circulating cooling of the present invention will be described in more detail with reference to the schematic drawings, in which preferred embodiments of the present invention are shown, it being understood that those skilled in the art can modify the utility model described herein while still achieving the advantageous effects of the utility model. Accordingly, the following description should be construed as broadly as possible to those skilled in the art and not as limiting the utility model.
The utility model is described in more detail in the following paragraphs by way of example with reference to the accompanying drawings. Advantages and features of the present invention will become apparent from the following description and from the claims. It is to be noted that the drawings are in a very simplified form and are not to precise scale, which is merely for the purpose of facilitating and distinctly claiming the embodiments of the present invention.
As shown in fig. 1, an embodiment of the present invention provides an integrated ultrasonic cell crusher with cooling and temperature control by water circulation, which includes a case 1, a transducer 2 is disposed on a top surface of the case 1, a knob switch 3, a transducer socket 4, and a temperature detection socket 5 are disposed on an upper portion of a back surface of the case 1, a power switch 6, a fuse 7, and a power socket 8 are disposed on a lower portion of the back surface of the case 1, a display panel 9 and a touch screen 10 are disposed on an upper portion of a front surface of the case 1, a working chamber 11 and a case door 12 are disposed on a lower portion of the case 1, a cooling chamber 13 is disposed inside the working chamber 11, a temperature control probe 14 and an amplitude transformer 15 are disposed above the cooling chamber 13, an LED lighting lamp 16 is disposed on a left side of the cooling chamber 13, as shown in fig. 4, an opening 17 is disposed on an upper surface of the cooling chamber 13, a plurality of clamping sliders 18 are disposed outside the opening 17, the clamping sliders 18 are all slidably mounted on the upper surface of the cooling chamber 13 through a mounting chute 19, and the clamping slide blocks 18 are all connected with fastening bolts 20 in a penetrating and sliding manner, and the lower ends of the fastening bolts 20 are all in threaded connection with the upper surface of the cooling groove 13.
Placing a test tube filled with cells at an opening 17 on a cooling tank 13, pushing a clamping slide block 18, enabling one end, close to the opening 17, of the clamping slide block 18 to be in contact with the outer wall of the test tube, then screwing a fastening bolt 20, so that clamping and positioning of the test tube can be realized, then opening a switch of the cooling tank 13, arranging a water-cooling circulating device inside the cooling tank 13, cooling water through semiconductor refrigeration equipment, then cooling the cells in the test tube through circulation of the cooling water, measuring the temperature of the cells in the test tube through a temperature control probe 14, and after the cells reach a preset temperature, performing crushing treatment on the cells in the test tube through an amplitude transformer 15; the fuse 7 includes at least two types, 5A and 8A, and the display panel 9 displays operation information and temperature information and performs operation selection through the touch screen 10.
As shown in fig. 4, the clamping blocks 18 are provided with anti-slip pads 21 at ends thereof near the openings 17, and the anti-slip pads 21 are provided with arc shapes. In this embodiment, set up slipmat 21 for press from both sides tight slider 18 and be convenient for press from both sides tight location to the test tube, avoid the test tube to skid and fall, and slipmat 21 has buffering protect function, causes the damage with avoiding pressing from both sides tight slider 18 to the test tube.
As shown in fig. 3, a cooling tank tray 22 is fixedly connected to the bottom surface of the cooling tank 13, a plurality of telescopic loop bars 23 are symmetrically arranged on the bottom surface of the cooling tank tray 22, the lower ends of the telescopic loop bars 23 are fixedly mounted on the bottom surface of the chassis 1, an electric push rod 24 is connected to the bottom surface of the cooling tank tray 22 in a transmission manner, and the lower end of the electric push rod 24 is fixedly mounted at the bottom of the chassis 1. In this embodiment, electric putter 24 is a linear reciprocating motion's that changes the rotary motion of motor into the push rod electric drive device, has the auto-lock characteristic, flexible loop bar 23 includes that a plurality of mutual cover establish and sliding connection's pipe, when realizing that length is flexible, also has limit function, can avoid cooling tank tray 22 off normal, through electric putter 24's extension, make cooling tank tray 22 drive cooling tank 13 and realize altitude mixture control, realize the contact of test tube and luffing jib 15 and control by temperature change probe 14.
As shown in fig. 2, a heat dissipation fan 26 and a plurality of heat dissipation holes 25 are disposed on the back of the chassis 1. In the present embodiment, the heat dissipation hole 25 and the heat dissipation fan 26 are provided to facilitate heat dissipation inside the enclosure 1.
The following examples are given for the purpose of illustrating the contents of the present invention clearly, and it should be understood that the contents of the present invention are not limited to the following examples, and other modifications by conventional means of the ordinary skill in the art are within the scope of the idea of the present invention.
The embodiment of the utility model provides a using method of an integrated ultrasonic cell crusher for cooling and controlling temperature through water circulation, which comprises the following specific steps: firstly, opening a box door 12, placing a test tube filled with cells at an opening 17 of a cooling tank 13, pushing a clamping slide block 18, enabling one end, close to the opening 17, of the clamping slide block 18 to be in contact with the outer wall of the test tube, then screwing a fastening bolt 20, so that the clamping and positioning of the test tube can be realized, then opening a switch of the cooling tank 13, arranging a water-cooling circulating device inside the cooling tank 13, cooling the cooling water through semiconductor refrigeration equipment, then circulating the cooling water, so that the cells in the test tube are cooled, opening an electric push rod 24, driving the cooling tank 13 to realize height adjustment through the extension of the electric push rod 24, realizing the contact of the test tube with an amplitude transformer 15 and a temperature control probe 14, measuring the temperature of the cells in the test tube through the temperature control probe 14, enabling the amplitude transformer 15 to be in contact with a liquid medium in the test tube, and converting electric energy into sound energy through an energy converter 2 after the cells reach a preset temperature, the horn 15 transmits acoustic energy to the liquid in the test tube, and the liquid is oscillated to break the cells in the liquid.
To sum up, press from both sides tight location through the test tube of pressing from both sides tight slider 18 in to cooling bath 13, and cooling bath 13 cools down to the cell in the test tube simultaneously, waits that the cell cools down to predetermineeing the temperature, can carry out broken handle to the cell, need not to shift the test tube, improves broken handle's of cell efficiency and effect.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the utility model. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (4)

1. An integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling is characterized by comprising a case, wherein a transducer is arranged on the top surface of the case, a knob switch, a transducer socket and a temperature detection socket are arranged on the upper portion of the back surface of the case, a power switch, a fuse and a power socket are arranged on the lower portion of the back surface of the case, a display panel and a touch screen are arranged on the upper portion of the front surface of the case, a working chamber and a case door are arranged on the lower portion of the case, a cooling groove is arranged in the working chamber, a temperature control probe and an amplitude transformer are arranged above the cooling groove, an LED illuminating lamp is arranged on the left side of the cooling groove, an opening is arranged on the upper surface of the cooling groove, a plurality of clamping sliding blocks are arranged on the outer side of the opening, the clamping sliding blocks are slidably mounted on the upper surface of the cooling groove through mounting sliding grooves, and fastening bolts are slidably connected on the clamping sliding blocks, the lower ends of the fastening bolts are in threaded connection with the upper surface of the cooling tank.
2. The integrated ultrasonic cell crusher with water circulation cooling temperature control function according to claim 1, wherein the clamping slide blocks are provided with non-slip pads at one ends close to the openings, and the non-slip pads are arc-shaped.
3. The integrated ultrasonic cell crusher with water circulation cooling temperature control according to claim 1, wherein the cooling tank tray is fixedly connected to the bottom surface of the cooling tank, a plurality of telescopic loop bars are symmetrically arranged on the bottom surface of the cooling tank tray, the lower ends of the telescopic loop bars are fixedly mounted on the bottom surface of the cabinet, an electric push rod is connected to the bottom surface of the cooling tank tray in a transmission manner, and the lower end of the electric push rod is fixedly mounted on the bottom of the cabinet.
4. The integrated ultrasonic cell crusher with water circulation cooling and temperature control functions as claimed in claim 1, wherein a heat dissipation fan and a plurality of heat dissipation holes are arranged on the back of the case.
CN202121980421.7U 2021-08-23 2021-08-23 Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling Active CN216063644U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121980421.7U CN216063644U (en) 2021-08-23 2021-08-23 Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121980421.7U CN216063644U (en) 2021-08-23 2021-08-23 Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling

Publications (1)

Publication Number Publication Date
CN216063644U true CN216063644U (en) 2022-03-18

Family

ID=80671329

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121980421.7U Active CN216063644U (en) 2021-08-23 2021-08-23 Integrated ultrasonic cell crusher capable of controlling temperature through water circulation cooling

Country Status (1)

Country Link
CN (1) CN216063644U (en)

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