CN215986770U - Cornea plastic mirror for reshaping front surface shape of cornea - Google Patents

Cornea plastic mirror for reshaping front surface shape of cornea Download PDF

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Publication number
CN215986770U
CN215986770U CN202121670993.5U CN202121670993U CN215986770U CN 215986770 U CN215986770 U CN 215986770U CN 202121670993 U CN202121670993 U CN 202121670993U CN 215986770 U CN215986770 U CN 215986770U
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cornea
region
mirror
orthokeratology
orthokeratology mirror
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刘熠
尚利如
崔秀国
李国丹
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Shanghai Aikangte Medical Technology Co ltd
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Zhuhai Weishi Aikangte Pharmaceutical Technology Co ltd
Shanghai Aikangte Medical Technology Co ltd
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    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes

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  • Ophthalmology & Optometry (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Prostheses (AREA)

Abstract

The utility model describes a corneal shaping mirror for reshaping the anterior surface of a cornea, the corneal shaping mirror having an inner surface configured to change the distribution of epithelial cells on the anterior surface of the cornea and an outer surface opposite to the inner surface, the inner surface being continuously formed from the center outwards with a base arc region, an annular inversion region, and an annular fitting region, the base arc region being formed to be aspherical and configured to reshape central tissue of the cornea so that central incident light rays are focused on the retina, the radius of curvature of the inversion region being smaller than that of the base arc region and the inversion region being configured to reshape central tissue of the cornea so that peripheral incident light rays are focused in front of the retina, the fitting region being aspherical and configured for positioning of the corneal shaping mirror. According to the utility model, the cornea shaping mirror for myopia control, which is designed to be an aspheric surface of the fitting area and can reshape the front surface shape of the cornea, can be provided.

Description

Cornea plastic mirror for reshaping front surface shape of cornea
Technical Field
The present invention generally relates to a corneal shaping mirror for reshaping the anterior surface of the cornea.
Background
The Orthokeratology (OK) lens is a rigid corneal contact lens, which adopts an inverse geometric design to make corneal epithelium migrate, and the redistribution of corneal epithelial cells changes the geometric shape of the corneal surface to correct the vision, and can delay the increase of the length of the ocular axis and slow down the deepening of the myopia while correcting the vision.
At present, a orthokeratology lens is generally designed as a spherical surface, that is, an inner lens surface of the orthokeratology lens is formed by connecting a plurality of spherical surfaces with different curvature radiuses. However, when the cornea is steep and the K value of the cornea is large, the reshaped cornea can generate a large peripheral defocus amount by using the spherical orthokeratology mirror, but when the cornea is flat and the K value of the cornea is small, the peripheral defocus amount generated by the reshaped cornea is small, so that a sufficient defocus amount is difficult to form, and effective control of myopia development cannot be realized. In addition, the cornea of human eyes has asphericity, and the wearing stability and the wearing comfort of the corneal plastic lens can be influenced by using the spherical corneal plastic lens.
Disclosure of Invention
The present invention has been made in view of the above-mentioned state of the art, and an object of the present invention is to provide a corneal shaping mirror for myopia control that can reshape the anterior surface of a cornea by fitting an aspherical surface design in a fitting region.
To this end, a orthokeratology mirror for reshaping an anterior surface of a cornea, the orthokeratology mirror having an inner surface configured to alter a distribution of anterior surface epithelial cells of the cornea, and an outer surface opposite the inner surface, the inner surface is continuously provided with a base arc area, an annular reverse area and an annular matching area from the center to the outside, the base arc region is formed to be aspherical and configured to reshape central corneal tissue to focus central incident light on the retina, the base arc region having a central region and a peripheral region surrounding the central region, the central region having a radius of curvature less than the radius of curvature of the peripheral region, the radius of curvature of the inversion region is less than the radius of curvature of the base arc region and the inversion region is configured to reshape the central peripheral tissue of the cornea such that peripheral incident light rays are focused in front of the retina, the fitting area is formed to be aspherical and configured for positioning of the orthokeratology mirror. In the utility model, the basal arc area of the inner surface of the orthokeratology mirror is of an aspheric design, the curvature radius of the central area of the basal arc area is smaller than that of the peripheral area of the basal arc area, namely the peripheral area of the basal arc area is flatter than that of the central area, so that epithelial cells in the central part of the cornea can move to the middle and peripheral parts of the cornea, the middle and peripheral parts of the cornea can be steepened, the curvature is increased, and the eyeball can form a myopic defocusing signal on the peripheral retina, and the increase of the length of the eye axis can be inhibited; the fitting area is in an aspheric surface shape, so that the shape matching degree of the corneal shaping mirror and a cornea with the same aspheric surface is higher, the positioning of the corneal shaping mirror is more accurate, and the wearing is more comfortable.
In the orthokeratology mirror according to the present invention, the fitting region may be divided into two quadrants, and the shapes of the quadrants may be matched to the shapes of the upper and lower corneas, respectively. In this case, since the quadrant asymmetry of the cornea becomes more pronounced the closer the cornea is to the periphery, the quadrant-specific design can improve the matching of the orthokeratology mirror to the cornea in each quadrant, thereby better matching to the shape of the cornea, contributing to evenly dispersing the pressure on the cornea caused by the orthokeratology mirror, and improving the reliability and comfort of the orthokeratology mirror.
In the orthokeratology mirror according to the present invention, the fitting area may be divided into four quadrants, and the four quadrants may be shaped to match the shapes of the cornea on the upper side, the nasal side, the lower side, and the temporal side, respectively. In this case, since the quadrant asymmetry of the cornea becomes more pronounced the closer the cornea is to the periphery, the quadrant-specific design can improve the matching of the orthokeratology mirror to the cornea in each quadrant, thereby better matching to the shape of the cornea, contributing to evenly dispersing the pressure on the cornea caused by the orthokeratology mirror, and improving the reliability and comfort of the orthokeratology mirror.
In addition, in the orthokeratology mirror according to the present invention, a rake angle for tear exchange is optionally formed at the outer edge of the fitting region. This can facilitate the circulation of tear fluid.
In addition, in the orthokeratology mirror according to the present invention, optionally, at least a portion of the fitting region is in contact with the cornea. Therefore, the orthokeratology mirror can be positioned on the cornea conveniently.
In addition, in the orthokeratology lens of the present invention, optionally, the fitting region is in contact with and positioned on the sclera. Therefore, the fitting area of the orthokeratology lens can be in contact with the sclera and positioned without being in contact with the sensitive cornea, so that the wearing comfort is improved.
In addition, in the orthokeratology mirror according to the present invention, optionally, the width of the fitting region is 0.75mm to 2 mm.
In addition, in the orthokeratology mirror related to the utility model, optionally, after the orthokeratology mirror is shaped, the amount of myopic defocus generated by the cornea is 0D to 5D. Therefore, the cornea shaping mirror can effectively control the myopia development.
In addition, in the orthokeratology mirror according to the present invention, optionally, the surface shape of the inner surface is the same as the surface shape of the outer surface, and the orthokeratology mirror has a uniform thickness. Therefore, the friction to the cornea is reduced, the incarceration incidence rate is reduced, and the safety and the comfort are improved.
In addition, in the orthokeratology mirror according to the present invention, optionally, the orthokeratology mirror has a thickness of 0.16mm to 0.30 mm. Therefore, the air permeability of the orthokeratology mirror can be improved.
According to the utility model, the cornea shaping mirror for myopia control, which is designed to be an aspheric surface of the fitting area and can reshape the front surface shape of the cornea, can be provided.
Drawings
Embodiments of the utility model will now be explained in further detail, by way of example only, with reference to the accompanying drawings, in which:
fig. 1 is a schematic view showing a state of use of a orthokeratology mirror for reshaping the anterior surface of a cornea according to an example of the present invention.
Fig. 2 is a schematic perspective view showing a corneal shaping mirror for reshaping the anterior surface of a cornea according to an exemplary embodiment of the present invention.
Figure 3 is a schematic diagram showing a longitudinal section through the center of a orthokeratology mirror according to an example of the utility model.
Figure 4 is a top projection view showing a keratoplasty mirror according to an example of the present invention.
Fig. 5 is a schematic view showing a state in which a keratoplasty mirror according to an example of the present invention is attached to the cornea.
Figure 6 is an enlarged partial view of the orthokeratology lens showing region S of figure 5.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments. In the drawings, the same components or components having the same functions are denoted by the same reference numerals, and redundant description thereof will be omitted.
The orthokeratology mirror 1 for reshaping the anterior surface of the cornea according to the present embodiment (hereinafter referred to as "orthokeratology mirror 1") may have an inner surface 10 and an outer surface 20, and the outer surface 20 may be opposite to the inner surface 10. In addition, the inner surface 10 of the orthokeratology lens 1 may face the anterior surface of the cornea when the orthokeratology lens 1 is worn. In this embodiment, the change in shape of the cornea 2 may be reversible, and the shape of the cornea 2 may return to the original state over time. In some examples, the orthokeratology mirror 1 according to the present embodiment may be worn at night or worn at day.
In this embodiment, the inner surface 10 may be configured to change the shape of the anterior surface of the cornea (simply "cornea 2"). For example, the inner surface 10 may flatten the central portion of the cornea and steepen the central portion of the cornea.
In some examples, the inner surface 10 may be configured to alter the distribution of corneal anterior surface epithelial cells. In addition, the inner surface 10 may alter the epithelial cell layer of the anterior surface of the cornea to alter the anterior surface shape of the cornea. For example, the inner surface 10 may move the corneal anterior surface epithelial cells from the central portion of the cornea to the central portion of the cornea, and the inner surface 10 may decrease the number of the corneal central portion epithelial cells and increase the number of the peripheral portion epithelial cells in the cornea.
In some examples, the inner surface 10 may alter the distribution of corneal anterior surface epithelial cells to alter the corneal anterior surface shape. Specifically, the inner surface 10 can change the shape of the anterior surface of the cornea by causing the anterior surface epithelial cells to migrate from the central portion of the cornea to the central portion of the cornea. Thus, the orthokeratology mirror 1 can reshape the anterior surface of the cornea.
Fig. 1 is a schematic view showing a usage state of a keratoplasty mirror 1 according to an example of the present invention. Fig. 2 is a schematic perspective view showing a keratoplasty mirror 1 according to an example of the present invention. Fig. 5 is a schematic view showing a state in which a keratoplasty mirror 1 according to an example of the present invention is attached to a cornea 2.
In some examples, the inner surface 10 may be concave and the outer surface 20 may be convex (see fig. 2).
As shown in fig. 1, the orthokeratology mirror 1 according to the present embodiment can be applied to the surface of the eyeball, specifically, the orthokeratology mirror 1 can be applied to the anterior surface of the cornea, and the shape of the anterior surface of the cornea can be changed to be substantially the same as the shape of the inner surface 10 of the orthokeratology mirror 1, thereby enabling correction of vision and control of myopia progression.
In some examples, as shown in fig. 1 and 5, when the keratoplastic lens 1 is worn, the keratoplastic lens 1 and the cornea 2 form a tear space C. In addition, in some examples, there may be an unevenly distributed tear layer (lachrymal lens) between the orthokeratology lens 1 and the cornea 2 for shaping the cornea 2 when the orthokeratology lens 1 is worn. In other examples, the anterior corneal surface epithelial cells can move from the central portion of the cornea to reshape the anterior corneal surface.
In some examples, the orthokeratology mirror 1 according to the present embodiment may have a multi-arc design. Specifically, the inner surface 10 of the orthokeratology mirror 1 may be formed by a plurality of arcs joined together, and the plurality of arcs may be joined together from the center to the outside. For example, the inner surface 10 may be formed by joining 3, 4, 5, 6, 7, or 8 arcs.
In some examples, the orthokeratology mirror 1 may be a three zone design. In other examples, the inner surface 10 of the orthokeratology mirror 1 may have a base zone 11, an inversion zone 12, and a fitting zone 13. In addition, adjacent zone control techniques may be employed between the zones (e.g., base arc zone 11, inversion zone 12, and adaptation zone 13). Therefore, the regions can be relatively independent, namely, no linkage relation exists among the region parameters, and the control of the region parameters can be facilitated.
Fig. 3 is a schematic diagram showing a longitudinal section through the center of a orthokeratology mirror 1 according to an example of the utility model. Fig. 4 is a top projection view showing a keratoplasty mirror 1 according to an example of the present invention.
In some examples, as shown in fig. 3, the inner surface 10 may have a base arc region 11, an inversion region 12, and a fitting region 13. In other examples, as shown in fig. 4, the base arc region 11, the inversion region 12, and the adaptation region 13 may be sequentially connected from the center to the outside. In other words, the inner surface 10 may be continuously formed with the base arc region 11, the inversion region 12, and the fitting region 13 from the center outward.
In some examples, the base arc region 11 may be located at a central position of the inner surface 10. In addition, the base zone 11 can flatten the central portion of the cornea, thereby allowing the eyeball to assume an emmetropic state.
In some examples, the base arc zone 11 may correspond to the anterior surface of the central portion of the cornea (hereinafter referred to as "central portion of the cornea") when the orthokeratology lens 1 is worn. This makes it possible to change the tissue morphology of the central part of the cornea to be substantially the same as the shape of the basal arc region 11. In the present invention, the central part of the cornea may be a central optical zone of the cornea 2. In other examples, the central portion of the cornea may focus parallel incident light rays on the retina after being shaped by the orthokeratology mirror 1. This enables correction of naked eye vision. In other words, the central part of the cornea can focus parallel incident light rays on the retina after changing the distribution of the epithelial cells on the anterior surface of the cornea.
In some examples, base arc region 11 may be configured as an aspheric shape that thins the number of epithelial cell layers in the central portion of the cornea. In other examples, the orthokeratology mirror 1 may apply positive pressure to the central portion of the cornea through the base arc region 11 to reduce the number of epithelial cells in the central portion of the cornea and increase the number of epithelial cells in the central portion of the cornea. In addition, the reduction in the number of epithelial cells in the central portion of the cornea can flatten the central portion of the cornea.
In other words, the base curve region 11 may be configured to have an aspherical shape that allows the corneal anterior surface epithelial cells to travel from the central portion of the cornea to the central portion of the cornea. This can flatten the central part of the cornea.
In some examples, base arc region 11 may be configured to be aspheric in shape. In other examples, base arc region 11 may be configured as an aspheric shape that reshapes the central tissue of the cornea such that parallel incident light rays are focused on the retina (central retina). That is, reshaping the central tissue of the cornea allows parallel incident light rays to be focused on the retina. In other words, after being shaped by the orthokeratology mirror 1, the central part of the cornea can make the central image fall on the retina.
In some examples, base arc region 11 may be configured to have an aspheric shape with a gradual change in radius of curvature in the radial direction. I.e. the aspherical shape may have a gradual change in the radius of curvature in the radial direction.
In some examples, as shown in fig. 3 and 4, the base arc zone 11 may include a central zone 11a and a peripheral zone 11 b. In addition, in the base arc region 11, the peripheral region 11b may surround the central region 11 a. In other examples, the base arc region 11 may have a central region 11a and a peripheral region 11b surrounding the central region 11 a.
In some examples, the radius of curvature of the central region 11a may be different from the radius of curvature of the peripheral region 11b in the base arc region 11.
In some examples, the peripheral region 11b may be flatter than the central region 11a in the base arc region 11. In other words, the radius of curvature of the peripheral region 11b may be greater than the radius of curvature of the central region 11a, i.e., the radius of curvature of the central region 11a may be less than the radius of curvature of the peripheral region 11 b. In this case, it is possible to contribute to migration of epithelial cells in the central part of the cornea to the central part of the cornea during corneal remodeling.
In some examples, the radius of curvature of the central region 11a may be substantially the same. That is, the radii of curvature of the points in the central region 11a may be substantially the same. In this case, the central region 11a can be spherically shaped, whereby the corresponding corneal region can be shaped spherically, which is advantageous for visual clarity. In the present invention, in the central region 11a, the error in the radius of curvature is less than 1%.
In some examples, the radius of curvature of the peripheral region 11b may gradually increase as one moves away from the central region 11 a. Specifically, the radius of curvature of the peripheral region 11b may gradually increase from the boundary between the peripheral region 11b and the central region 11a to the edge of the peripheral region 11 b. In other words, the radius of curvature of the peripheral region 11b of the base arc region 11 may gradually increase as the radial distance of the peripheral region 11b increases. In this case, the peripheral region 11b can be aspheric in shape, which can contribute to the formation of myopic defocus after corneal reshaping.
In some examples, the radius of curvature of base arc region 11 may gradually increase from the center outward. Specifically, the radius of curvature of the base arc region 11 may gradually increase from the center of the central region 11a to the edge of the peripheral region 11 b. In other words, the radius of curvature of the base arc region 11 may gradually increase as the radial distance of the base arc region 11 increases.
In some examples, base arc zone 11 may be flatter than the central portion of the cornea prior to reshaping. In other words, the base arc region 11 may have a radius of curvature greater than the central portion of the cornea prior to remodeling. Therefore, the cornea shaping mirror 1 can play a shaping role, and the basal arc zone 11 can flatten the central part of the cornea, change the myopic dioptric state and improve the vision. Specifically, the base arc region 11 can reduce the number of epithelial cells in the central part of the cornea, flatten the wing cells, and thin the central part of the cornea.
In some examples, the base arc region 11 may be an aspheric shape formed by combining multiple arc segments. For example, the base arc region 11 may be an aspheric shape formed by combining two arc segments. Additionally, in some examples, the radius of curvature of the central region 11a may be substantially the same, the radius of curvature of the peripheral region 11b may be substantially the same, and the radius of curvature of the central region 11a may be less than the radius of curvature of the peripheral region 11 b. In some examples, base arc region 11 may be an aspheric shape of a combination of three, four, or five arc segments.
In some examples, the base arc zone 11 may not be in contact with the cornea 2. In some examples, the base arc region 11 may be spaced from the cornea 2 by 5 μm to 10 μm. For example, the base arc region 11 may be spaced 5 μm, 5.5 μm, 6 μm, 6.5 μm, 7 μm, 8 μm, 9 μm, or 10 μm from the cornea 2. In addition, tears may be present between the base zone 11 and the cornea 2.
In some examples, the diameter D of the base arc zone 11 is set according to a predetermined shape of the cornea 2. This can further contribute to flattening the central part of the cornea. In some examples, the diameter D of the base arc zone 11 may be greater than or equal to the diameter of the pupil, i.e., the base arc zone 11 can cover at least the area where the pupil is located. In other words, the orthokeratology lens 1 can at least cause a change in the shape of the cornea in the pupillary region.
In some examples, the diameter D of the base arc region 11 may be 5mm to 7 mm. Thereby, the corneal optic zone can be shaped, i.e. the distribution of epithelial cells on the anterior surface of the corneal optic zone can be changed. For example, the diameter D of the base arc region 11 may be 5mm, 5.2mm, 5.5mm, 5.7mm, 6mm, 6.2mm, 6.5mm, 6.7mm, or 7 mm. In addition, the diameter D of the basal arc zone 11 can be adjusted, so that the pressure is transmitted to the central part of the cornea more quickly and thoroughly, the shaping is easier, and the myopia prevention and control are facilitated.
In some examples, the diameter D of the base arc zone 11 may be preferably 5mm to 6mm for the purpose of enhancing the myopia prevention and control effect. Under the condition, the pressure conduction can be enhanced to accelerate the cornea shaping, so that the cornea 2 can form larger myopic defocusing, and the myopia prevention and control effect is improved.
In some examples, the diameter d of the central region 11a of the base arc region 111May be 1mm to 2 mm. This can change the shape of the cornea in the pupil region, and can contribute to the optical effect in the central region. For example, the diameter d of the central region 11a1May be 1mm, 1.1 mm, 1.2mm, 1.3mm, 1.4mm, 1.5mm, 1.6mm, 1.7mm, 1.8mm, 1.9mm or 2 mm.
In some examples, the width d of the peripheral region 11b of the base arc zone 112And may be 2mm to 3 mm. This can change the shape of the cornea near the pupil, and can contribute to migration of epithelial cells in the central part of the cornea to the middle peripheral part of the cornea. For example, the width d of the peripheral region 11b2May be 2mm, 2.1mm, 2.2mm, 2.3mm, 2.4mm, 2.5mm, 2.6 mm, 2.7mm, 2.8mm, 2.9mm or 3 mm.
In some examples, as shown in fig. 3, the width d of the peripheral region 11b in a longitudinal section passing through the center of the orthokeratology mirror 12Refers to the projection distance from the end of the peripheral region 11b connected to the central region 11a to the plane where the other end of the peripheral region 11b connected to the central region 11a lies on the end of the peripheral region 11b connected to the central region 11 a. In addition, the longitudinal section along the center of the orthokeratology mirror 1 may refer to the section of the orthokeratology mirror 1 along the sagittal height of the center of the orthokeratology mirror 1.
In some examples, as shown in fig. 4, the inversion region 12 may be disposed at the periphery of the base arc region 11 and surround the base arc region 11. In addition, the reversal zone 12 can collect tears to promote the flattening of the central part of the cornea by the base arc zone 11.
In some examples, the reversal zone 12 may correspond to the anterior surface of the mid-peripheral portion of the cornea (hereinafter "mid-peripheral portion of the cornea") when the orthokeratology lens 1 is worn. In the present embodiment, the mid-peripheral portion of the cornea may be referred to as the paracorneal central region 11 a.
In some examples, the inversion region 12 may not be in contact with the cornea 2. In other examples, tears may be present between the inversion region 12 and the cornea 2. In addition, the tear thickness between the reversal zone 12 and the cornea 2 may be greater than the tear thickness between the base arc zone 11 and the cornea 2. In some examples, tear fluid between the reversal region 12 and the cornea 2 may create a negative pressure attraction. This promotes the migration of corneal anterior epithelial cells from the central part of the cornea to the intermediate peripheral part of the cornea.
In some examples, the reversal zone 12 may form with the cornea 2 a space that accommodates tear fluid and corneal anterior surface epithelial cells that travel from the central portion of the cornea to the central portion of the cornea, and the reversal zone 12 may transition between the basal arc zone 11 and the fitting zone 13.
In some examples, the depth h of the inversion region 12 may be 0.2mm to 0.9mm, and the width d of the inversion region 123And may be 0.45mm to 2.2 mm. This makes it possible to compensate for the change in sagittal depth due to the difference between the base curve and the corneal central curvature, and is advantageous for the formation of a more significant steepening change in the cornea mid-peripheral region.
In some examples, the depth h of the inversion region 12 may be 0.2mm, 0.300mm, 0.400 mm, 0.500mm, 0.600mm, 0.700mm, 0.800mm, or 0.9 mm.
In some examples, the width d of the inversion region 123May be 0.45mm, 0.5mm, 0.6mm, 0.8mm, 1mm, 1.2mm, 1.5mm, 1.8mm, 2mm or 2.2 mm.
In some examples, as shown in fig. 3, the depth h of the inversion region 12 in a longitudinal section passing through the center of the orthokeratology mirror 1 may refer to the distance from the end of the inversion region 12 connected to the base arc region 11 to the plane where the other end of the inversion region 12 connected to the fitting region 13 is located. In some examples, as shown in fig. 3, in a longitudinal section through the center of the orthokeratology mirror 1, the inversion zone12 width d3Refers to the projection distance from one end of the inversion region 12 connected with the adaptation region 13 to the other end of the inversion region 12 connected with the base arc region 11 on the plane where the end of the inversion region 12 connected with the adaptation region 13 is located.
In some examples, the reversal zone 12 may reshape the peripheral tissue in the cornea (altering the corneal central epithelial cell distribution) to enable the cornea 2 to develop myopic defocus. Specifically, the reversal zone 12 can apply negative pressure to the cornea 2 to reshape the central and intermediate corneal tissue (redistribute the central and intermediate corneal epithelium) to enable the cornea 2 to develop myopic defocus. In other examples, the mid-peripheral portion of the cornea may focus peripheral incident light in front of the retina after being shaped by the orthokeratology mirror 1. Thereby, near-sighted peripheral defocus can be formed in an naked eye state. In other words, the mid-periphery of the cornea can focus peripheral incident light rays in front of the retina after changing the distribution of the corneal anterior surface epithelial cells.
In some examples, in the naked eye state after being shaped by the orthokeratology mirror 1, the central part of the cornea focuses parallel incident light rays on the retina, and the central part of the cornea focuses peripheral incident light rays in front of the retina.
In some examples, the inversion region 12 may be configured to shape the corneal mid-peripheral tissue to focus peripheral incident light rays in front of the retina (peripheral retina). That is, reshaping the peripheral tissue in the cornea allows peripheral incident light rays to be focused in front of the retina. In other words, after being shaped by the orthokeratology mirror 1, the middle periphery of the cornea can make the peripheral image fall in front of the retina.
In some examples, the reversal zone 12 may be configured to accelerate the migration of corneal anterior surface epithelial cells from the central portion of the cornea to the mid-peripheral portion of the cornea. Additionally, in some examples, the reversal zone 12 may be configured to receive the shape of the anterior surface epithelial cells of the cornea traveling from the central portion of the cornea to the central portion of the cornea.
In some examples, the reversal zone 12 may create negative pressure around the center of the cornea by the tear fluid effect to thin the number of layers of epithelial cells around the center of the cornea and to thicken the number of layers of epithelial cells around the center of the cornea. In addition, the increase in the number of epithelial cell layers in the middle and peripheral part of the cornea can make the middle and peripheral part of the cornea steep.
In some examples, after being shaped by the orthokeratology lens 1, the number of layers of epithelial cells in the middle periphery of the cornea increases, and the middle periphery of the cornea becomes thicker and steeper. This makes it possible to increase the refractive power of the cornea 2 in the middle peripheral portion of the cornea to be larger than the refractive power of the central portion of the cornea, and to form myopic defocus.
In some examples, the orthokeratology lens 1 may alter the distribution of the corneal anterior surface epithelial cells to alter the power profile of the cornea 2. Specifically, the orthokeratology mirror 1 can change the power distribution of the cornea 2 by moving the corneal anterior surface epithelial cells from the central portion of the cornea to the central portion of the cornea. In other words, the orthokeratology lens 1 can reshape the anterior surface of the cornea so that the power profile of the cornea 2 changes.
In some examples, the power of the central portion of the cornea may be greater than the power of the central portion of the cornea after being shaped by the orthokeratology lens 1. In this case, the shaped cornea 2 enables a peripheral image to be formed in front of the peripheral retina, thereby enabling myopic peripheral defocus to be formed. In other words, the power of the central portion of the cornea may be greater than the power of the central portion of the cornea after changing the distribution of the epithelial cells on the anterior surface of the cornea.
In some examples, the power of the cornea 2 may gradually increase from the central portion of the cornea to the intermediate peripheral portion of the cornea after being shaped by the orthokeratology mirror 1. This can help to form more myopic peripheral defocus. In other words, the refractive power of the cornea 2 can be gradually increased from the central portion of the cornea to the intermediate peripheral portion of the cornea after changing the distribution of the epithelial cells on the anterior surface of the cornea.
In some examples, the amount of myopic defocus generated by the cornea 2 after being shaped by the orthokeratology mirror 1 may be no less than zero. This can suppress the increase in the axial length of the eye and control the progression of myopia. In other words, the amount of myopic defocus produced by the cornea 2 may be no less than zero after altering the distribution of the corneal anterior surface epithelial cells.
In some examples, the amount of myopic defocus generated by the cornea 2 after being shaped by the orthokeratology mirror 1 may be 0D to 5D. In other words, the amount of myopic defocus produced by the cornea 2 may be 0D to 5D after changing the distribution of the corneal anterior surface epithelial cells. Thus, the orthokeratology mirror 1 can effectively control the myopia progression. For example, the amount of myopic defocus produced by the reshaped cornea 2 may be 0D, 0.5D, 1D, 1.5D, 2D, 2.5D, 3D, 3.5D, 4D, 4.5D, or 5D.
In some examples, as shown in fig. 3, the reversal zone 12 may be curved in a longitudinal section through the center of the orthokeratology mirror 1. Therefore, the whole orthokeratology mirror 1 can be smoother, and the orthokeratology effect is enhanced. In addition, the inversion region 12 may be S-shaped in a longitudinal section passing through the center of the orthokeratology mirror 1.
In some examples, as shown in fig. 3, the inversion region 12 may be steeper than the base arc region 11. In other words, the radius of curvature of the inversion region 12 may be smaller than the radius of curvature of the base arc region 11. This can contribute to accelerating the corneal remodeling speed and increasing the amount of myopic defocus formed by the cornea 2 (reshaped cornea 2). In some examples, the reversal region 12 may be configured to reshape the peripheral tissue in the cornea to focus peripheral incident light rays on the retina. That is, reshaping the peripheral tissue in the cornea allows peripheral incident light rays to be focused on the retina. In other words, after being shaped by the orthokeratology mirror 1, the middle periphery of the cornea can make the peripheral image fall on the retina.
Figure 6 is an enlarged partial view of the orthokeratology lens showing region S of figure 5.
In some examples, as shown in fig. 4, the fitting region 13 may be disposed at the periphery of the inversion region 12 and surround the inversion region 12. In addition, as shown in fig. 5 and 6, the fitting region 13 may be disposed in partial contact with the cornea 2. In other examples, the fitting region 13 may be used for positioning the orthokeratology mirror 1.
In some examples, the width d of the fitting region 134And may be 0.75mm to 2 mm. For example, the width d of the fitting region 134May be 0.75mm, 0.8mm, 0.9mm, 1mm, 1.2mm, 1.5mm, 1.8mm or 2 mm.
In some examples, as shown in fig. 3, in a longitudinal section passing through the center of the orthokeratology mirror 1, the width of the fitting region 13 may be a projection distance from one end of the fitting region 13 connected with the inversion region 12 to the other end of the fitting region 13 connected with the inversion region 12 on a plane where the one end of the fitting region 13 connected with the inversion region 12 is located.
In some examples, as shown in fig. 3, the outer edge of the fitting region 13 may have a rake angle Q in a longitudinal section passing through the center of the orthokeratology mirror 1. In this case, the fitting region 13 can be positioned in contact with the cornea 2, and the rake angle Q formed by the fitting region 13 and the cornea 2 can be used for tear exchange, which can facilitate tear circulation.
In some examples, the fitting region 13 may be an aspheric design. In this case, since the stable wearing of the orthokeratology mirror 1 is beneficial to shaping the cornea 2 into an ideal shape, but the cornea 2 has asphericity, the shape of the adaptation area 13 and the shape of the cornea 2 can be more matched through the aspherical design of the adaptation area 13, and the positioning accuracy and the adaptation comfort degree of the orthokeratology mirror 1 are improved.
In some examples, the fitting region 13 may be aspheric in shape to match the shape of the cornea 2. Therefore, the fitting stability and comfort of the orthokeratology mirror 1 can be improved.
In some examples, as shown in fig. 1 and 5, the fitting region 13 may be in facial contact with the cornea 2 when the orthokeratology lens 1 is worn. Thereby, the orthokeratology mirror 1 is positioned more firmly on the cornea 2.
In some examples, the adaptation zone 13 may be designed via quadrant partitioning. In this case, since the quadrant asymmetry of the cornea 2 is more pronounced the closer the cornea 2 is to the periphery, the quadrant-specific design can improve the matching of the orthokeratology mirror 1 to the cornea 2 in each quadrant, thereby better matching the shape of the cornea 2, contributing to evenly dispersing the pressure of the orthokeratology mirror 1 on the cornea 2, and improving the reliability and comfort of the orthokeratology mirror 1. That is, the adaptation region 13 may have non-rotational symmetry (or quadrant-specificity). Further, the orthokeratology mirror 1 may have non-rotational symmetry.
In some examples, the adaption zone 13 may be divided into quadrants for quadrant division design. Additionally, in some examples, the adaptation zone 13 may be divided into 2 quadrants for quadrant partition design. In other examples, the adaption zone 13 may be divided into a first quadrant and a second quadrant for quadrant division design.
In some examples, a first quadrant of the fitting region 13 may match the upper half of the cornea 2, and a second quadrant of the fitting region 13 may match the lower half of the cornea 2. In other words, a first quadrant of the fitting region 13 may be designed based on the shape of the cornea 2 of the corresponding upper half, and a second quadrant of the fitting region 13 may be designed based on the shape of the cornea 2 of the corresponding lower half.
In some examples, the adaption zone 13 may be divided into 4 quadrants for quadrant division design. In other examples, the adaptive area 13 may be divided into a first quadrant, a second quadrant, a third quadrant, and a fourth quadrant for quadrant division design.
In some examples, a first quadrant of the fitting zone 13 may be designed based on a corresponding superior corneal 2 shape, a second quadrant of the fitting zone 13 may be designed based on a corresponding nasal corneal 2 shape, a third quadrant of the fitting zone 13 may be designed based on a corresponding inferior corneal 2 shape, and a fourth quadrant of the fitting zone 13 may be designed based on a corresponding temporal corneal 2 shape. Wherein, the superior side can be a side of the cornea 2 near the superior rectus muscle, the inferior side can be a side of the cornea 2 near the inferior rectus muscle (away from the superior rectus muscle), the nasal side can be a side of the cornea 2 near the medial rectus muscle, and the temporal side can be a side of the cornea 2 near the lateral rectus muscle (away from the medial rectus muscle).
In some examples, the fit region 13 may be divided into 3, 5, 6, or 8 quadrants for quadrant partition design. In addition, the base arc area 11 can be designed in quadrant division according to actual requirements. Furthermore, the inversion region 12 can be designed in quadrant division according to actual requirements.
In some examples, the fitting region 13 may be a spherical design, an aspherical design, or a multi-arc segment combination design.
In other examples, the fitting region 13 may present a toric design, thereby enabling application to more patients (e.g., patients with large corneal astigmatism values).
In some examples, the contact position of the fitting region 13 with the eyeball may also be located in the sclera. That is, the compliant zone 13 may not be in contact with the cornea 2, and the compliant zone 13 may be in contact with and positioned to the sclera. Therefore, the plastic cornea mirror 1 is contacted with the insensitive sclera, so that the wearing comfort can be improved, and meanwhile, the plastic cornea mirror 1 can be suitable for patients with cornea diseases.
In some examples, as shown in fig. 6, the fitting region 13 may be connected with the outer surface 20 via an elliptical edge 30. In other words, the inner surface 10 and the outer surface 20 of the orthokeratology mirror 1 may be connected via the elliptical rim 30. Thereby, the inner surface 10 and the outer surface 20 can be smoothly connected to form the complete orthokeratology mirror 1.
In the present embodiment, the surface shape of the outer surface 20 is not particularly limited. For example, the outer surface 20 may be spherical, aspherical, toric, multifocal, or non-rotationally symmetric geometry.
In some examples, as shown in fig. 3 and 4, the surface shape of the outer surface 20 may be the same as the surface shape of the inner surface 10. Therefore, the cornea friction can be reduced, the incarceration incidence rate can be reduced, and the safety and the comfort degree can be improved.
In other examples, the orthokeratology lens 1 may provide a refractive power. In some examples, the outer surface 20 may be configured to combine with the inner surface 10 to provide a shape having a refractive effect or diopter of optical properties. In this case, the orthokeratology lens 1 can not only change the shape of the cornea 2 but also provide diopter power for correcting ametropia, thereby enabling correction of vision during wearing. In other examples, the orthokeratology lens 1 may not provide a refractive power.
In some examples, the outer surface 20 may be configured to provide a refractive effect that focuses the central image on the retina, the peripheral image in front of the retina, or on the retina. That is, outer surface 20 may be combined with inner surface 10 to provide a refractive effect that focuses the central image on the retina, the peripheral image in front of the retina, or on the retina.
In some examples, the orthokeratology lens 1 may be constructed of a rigid, highly oxygen permeable material. In this case, it is possible to provide both the orthokeratology mirror 1 with good oxygen permeability and to improve the abrasion resistance of the orthokeratology mirror 1 and to facilitate the production of the orthokeratology mirror 1.
In some examples, the oxygen permeability coefficient (DK value) of the hard high oxygen permeable material may be from 100 to 200. Therefore, the tear film has better oxygen permeability, so that the tear can provide oxygen for the cornea, and further, the health of the cornea is favorably maintained. For example, the DK values of the rigid high oxygen permeable material may be 100, 125, 141.
In some examples, the stiff, highly oxygen permeable material may be one or more selected from the group consisting of silicone methacrylate, fluorosilicone methacrylate, perfluoroether, fluorinated silicone. For example, the orthokeratology lens 1 may be made of fluorosilicone methacrylate.
In some examples, as shown in fig. 3 and 4, in the orthokeratology lens 1, the thickness of each portion of the lens may be uniform. Thereby, oxygen can be uniformly permeated. In other words, the orthokeratology mirror 1 has a uniform thickness. In other examples, the thickness of the lens may not be uniform throughout the lens in the orthokeratology lens 1.
In some examples, the orthokeratology lens 1 may have a thickness of 0.16mm to 0.30 mm. In this case, not only can the deformation of the lens of the orthokeratology mirror 1 be relieved, but also the overweight of the orthokeratology mirror 1 can be avoided, and the air permeability of the orthokeratology mirror 1 can be improved. For example, the orthokeratology lens 1 may have a thickness of 0.16mm, 0.18mm, 0.20mm, 0.22mm, 0.24mm, 0.26mm, 0.28mm, or 0.3 mm.
In the present embodiment, the base arc region 11 of the inner surface 10 of the orthokeratology mirror 1 has an aspheric design, and the radius of curvature of the central region 11a of the base arc region 11 is smaller than the radius of curvature of the peripheral region 11b of the base arc region 11, that is, the peripheral region 11b of the base arc region 11 is flatter than the central region 11a, thereby facilitating the epithelial cells in the central part of the cornea to migrate toward the central part of the cornea, thereby contributing to the steepening of the central part of the cornea and the increase in curvature, so that the eyeball can form a myopic defocus signal in the peripheral retina, thereby effectively suppressing the increase in the length of the eye axis and controlling the progression of myopia. Because the stable wearing of the orthokeratology mirror 1 is beneficial to shaping the cornea 2 into an ideal shape, but the cornea 2 has asphericity, in the embodiment, the shape of the adaptation area 13 is more matched with that of the cornea 2 through the aspherical design of the adaptation area 13, and the positioning precision and the adaptation comfort degree of the orthokeratology mirror 1 are improved.
In some examples, the orthokeratology lens 1 may be designed based on sagittal height. Thereby, fitting of the orthokeratology mirror 1 can be facilitated. In other examples, the inner surface 10 may be designed to have a continuous curved surface of a predetermined shape based on the rise. For example, the inner surface 10 may be designed to be aspherical based on rise. The orthokeratology lens 1 can adjust the lens fit by sagittal height adjustment. Further, in some examples, the sagittal height may be obtained based on the sagittal depth of the eyeball, i.e., the sagittal height may be obtained based on the sagittal depth of the cornea 2.
In some examples, the change in sagittal height of each region (e.g., base curve region 11, inversion region 12, and fitting region 13) may correspond to a change in the overall sagittal height of the lens. In other examples, there may be no linkage between the parameters of the base arc zone 11, the inversion zone 12, and the adaptation zone 13. This can contribute to accurate fitting of the orthokeratology mirror 1.
In some examples, the orthokeratology mirror 1 may use topography to guide the AI simulation fitting. Therefore, the fitting time can be reduced, the learning curve can be shortened, and the non-fitting piece can be realized.
According to the utility model, the cornea shaping mirror 1 for myopia control, which is designed to be an aspheric surface of a fitting area and can reshape the front surface shape of a cornea, can be provided.
While the utility model has been specifically described above in connection with the drawings and examples, it will be understood that the above description is not intended to limit the utility model in any way. Those skilled in the art can make modifications and variations to the present invention as needed without departing from the true spirit and scope of the utility model, and such modifications and variations are within the scope of the utility model.

Claims (10)

1. A orthokeratology mirror for reshaping the anterior surface of a cornea, the orthokeratology mirror having an inner surface configured to change the distribution of epithelial cells on the anterior surface of the cornea and an outer surface opposite to the inner surface, the inner surface being continuously formed from a center outward with a basal arc region, an annular inversion region, and an annular fitting region, the basal arc region being formed to be aspherical and configured to reshape central tissue of the cornea so that central incident light rays are focused on the retina, the basal arc region having a central region and a peripheral region surrounding the central region, a radius of curvature of the central region being smaller than a radius of curvature of the peripheral region, the inversion region having a radius of curvature smaller than the radius of curvature of the basal arc region and the inversion region being configured to reshape peripheral tissue in the cornea so that peripheral incident light rays are focused in front of the retina, the fitting area is formed to be aspherical and configured for positioning of the orthokeratology mirror.
2. The orthokeratology mirror of claim 1,
the fitting region is divided into two quadrants, the shape of which matches the shape of the cornea on the superior and inferior half sides, respectively.
3. The orthokeratology mirror of claim 1,
the fitting area is divided into four quadrants, and the shapes of the four quadrants are respectively matched with the shapes of the corneas on the upper side, the nose side, the lower side and the temporal side.
4. The orthokeratology mirror of claim 1,
the outer edge of the fitting area is provided with a rake angle for tear exchange.
5. The orthokeratology mirror of claim 1,
at least a portion of the fitting region is in contact with the cornea.
6. The orthokeratology mirror of claim 1,
the fitting region is in contact with and positioned to the sclera.
7. The orthokeratology mirror of claim 1,
the width of the fitting area is 0.75mm to 2 mm.
8. The orthokeratology mirror of claim 1,
after the cornea is shaped by the cornea shaping mirror, the amount of myopic defocus generated by the cornea is 0D to 5D.
9. The orthokeratology mirror of claim 1,
the surface shape of the inner surface is the same as that of the outer surface, and the thickness of the orthokeratology mirror is uniform.
10. The orthokeratology mirror of claim 9,
the thickness of the orthokeratology mirror is 0.16mm to 0.30 mm.
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