CN215985740U - Detection assembly for fluorescence analysis of blood sample - Google Patents
Detection assembly for fluorescence analysis of blood sample Download PDFInfo
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- CN215985740U CN215985740U CN202121119761.0U CN202121119761U CN215985740U CN 215985740 U CN215985740 U CN 215985740U CN 202121119761 U CN202121119761 U CN 202121119761U CN 215985740 U CN215985740 U CN 215985740U
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- 239000008280 blood Substances 0.000 title claims abstract description 37
- 210000004369 blood Anatomy 0.000 title claims abstract description 37
- 238000001514 detection method Methods 0.000 title claims abstract description 35
- 238000012921 fluorescence analysis Methods 0.000 title claims abstract description 32
- 230000003287 optical effect Effects 0.000 claims description 42
- 239000011521 glass Substances 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 3
- 239000000428 dust Substances 0.000 abstract description 5
- 239000012535 impurity Substances 0.000 abstract description 5
- 230000010354 integration Effects 0.000 abstract description 5
- 239000000126 substance Substances 0.000 description 6
- 238000010183 spectrum analysis Methods 0.000 description 5
- 230000005284 excitation Effects 0.000 description 4
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000007769 metal material Substances 0.000 description 2
- 102000036675 Myoglobin Human genes 0.000 description 1
- 108010062374 Myoglobin Proteins 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
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- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model discloses a detection assembly for fluorescence analysis of a blood sample, wherein a first inclined plane is arranged on a first main body; a first light path channel and a second light path channel are arranged in the first main body; one end of the first light path channel is intersected with one end of the second light path channel on the first inclined plane to form a first window; a second inclined plane is arranged on the second main body; a third light path channel is arranged in the second main body; one end of the third light path channel forms a second window on the second inclined plane; the first main body and the second main body are mutually matched and have a matched state; in a matching state, a mounting gap is formed between the first inclined surface and the second inclined surface; the light splitting lens is arranged in the mounting gap and is positioned between the first window and the second window. The utility model has compact structure and high integration degree of each component, effectively reduces the whole size of fluorescence analysis equipment, and in addition, impurities such as dust in the air can not contact with the spectroscope, thereby forming effective protection for the spectroscope.
Description
Technical Field
The utility model relates to a fluorescence analysis device, in particular to a detection assembly for fluorescence analysis of a blood sample.
Background
When detecting blood sample, the comparatively mature technique is through the content of free hemoglobin in the mode detection blood bag of chemical inspection, has the outstanding advantage that the accuracy is high, but the mode of chemical inspection need open the blood bag and take out the sample and carry out the chemical examination, can't satisfy quick, non-contact, pollution-free demand.
Hemoglobin, myoglobin, and other substances in the blood sample are excited by light of a specific waveband and can emit fluorescence. The spectrum formed by the fluorescence can be used to analyze the blood sample. The analysis method has the advantages of rapidness, no contact, no pollution and the like, and is a current hotspot technology. The integration degree of a light path component for transmitting light in the existing fluorescence analysis equipment is low, so that the whole equipment is too large and the occupied area is large. In addition, optical components such as lenses and spectroscopes in the optical path component are not well protected, and impurities such as dust in the air are easily contacted with the optical components, so that light transmission is blocked, and the detection quality of the blood sample is influenced. On the other hand, because the blood sample frequently contacts with the optical path component directly, conditions such as abrasion and pollution can occur at the contact position, so that the light is blocked during propagation, and the detection of the blood sample is not facilitated.
SUMMERY OF THE UTILITY MODEL
In view of the above technical problems, the present invention aims to: the detection assembly for the fluorescence analysis of the blood sample is compact in structure, the integration degree of each component is high, the overall size of fluorescence analysis equipment is effectively reduced, and in addition, impurities such as dust in the air cannot be in contact with the spectroscope lens, so that the spectroscope lens can be effectively protected.
The technical solution of the utility model is realized as follows: a detection assembly for fluorescence analysis of a blood sample comprises a first main body, a second main body and a light splitting lens; a first inclined plane is arranged on the first main body; a first light path channel extending along a first direction and a second light path channel extending along a second direction are arranged in the first main body; one end of the first light path channel is intersected with one end of the second light path channel on the first inclined plane to form a first window;
a second inclined plane is arranged on the second main body corresponding to the first inclined plane; a third light path channel is arranged in the second main body corresponding to the second light path channel; one end of the third light path channel forms a second window on the second inclined plane;
the first main body and the second main body are mutually matched and have a matched state; in the matched state, a mounting gap is formed between the first inclined surface and the second inclined surface, the first window and the second window correspond to each other in the second direction, and the second optical path channel and the third optical path channel correspond to each other in the second direction;
the light splitting lens is arranged in the mounting gap and positioned between the first window and the second window; the beam splitting mirror is for reflecting light of a first wavelength range and for transmitting light of a second wavelength range.
Further, the detection assembly includes a light source assembly; the first main body is provided with a first side surface; a light inlet hole is formed in the first side face at one end, far away from the first window, of the first light path channel; the light source component is arranged corresponding to the light inlet hole.
Further, a first top surface is arranged on the first main body; and a detection hole is formed in the first top surface at one end of the second light path channel, which is far away from the first window.
Further, a glass plate covers the first top surface; and avoidance holes are formed in the glass plate corresponding to the detection holes.
Further, the glass plate is detachably coupled to the first body.
Furthermore, a first slot for cutting off the first light path channel is arranged on the first main body; a first optical filter is arranged in the first slot.
Further, a focusing lens is arranged in the first light path channel.
Further, the detection assembly comprises a fluorescence analysis module; a second bottom surface is arranged on the second main body; a light ray outlet hole is formed in the second bottom surface at one end, far away from the second window, of the third light path channel; the fluorescence analysis module is arranged corresponding to the light outlet.
Further, a second slot for cutting off a third light path channel is arranged on the second main body; and a second optical filter is arranged in the second slot.
Due to the application of the technical scheme, compared with the prior art, the utility model has the following advantages:
1. according to the utility model, the first main body and the second main body are matched for use, the first light path channel, the second light path channel and the third light path channel are formed in the first main body and the second main body, the detection assembly has a compact integral structure and high integration degree, and the integral size of the fluorescence analysis equipment is effectively reduced. The light splitting lens is clamped between the first inclined plane and the second inclined plane, so that the light splitting lens is stable and reliable to fix, impurities such as dust in the air cannot contact with the light splitting lens, and the light splitting lens can be effectively protected.
2. According to the utility model, the first top surface of the first main body is covered with the glass plate, the blood sample is placed on the glass plate for fluorescence analysis, and the glass plate can be detached from the first main body, so that the glass plate can be replaced conveniently. The abrasion condition appears when the glass plate, and through replacing the glass plate, the light can not be blocked when being transmitted, thereby being beneficial to the detection of the blood sample.
Drawings
The technical scheme of the utility model is further explained by combining the accompanying drawings as follows:
FIG. 1 is a schematic three-dimensional structure of the overall structure of the present invention;
FIG. 2 is a schematic top view of the structure of FIG. 1;
FIG. 3 is a schematic cross-sectional view taken at A-A in FIG. 2;
FIG. 4 is a schematic three-dimensional structure of FIG. 1 from another perspective;
FIG. 5 is a schematic three-dimensional structure of a first body and a glass plate of the present invention;
FIG. 6 is a schematic three-dimensional structure of a first body according to the present invention;
FIG. 7 is a schematic three-dimensional structure of a second body according to the present invention;
FIG. 8 is a schematic three-dimensional structure of FIG. 7 from another perspective;
wherein: 1. a first body; 11. a first inclined plane; 12. a first window; 13. a first side surface; 14. a first optical path channel; 15. a first top surface; 16. a second optical path channel; 17. a first slot; 171. a first optical filter; 2. a second body; 21. a second inclined plane; 22. a second bottom surface; 23. a second window; 26. a third optical path channel; 27. a second slot; 271. a second optical filter; 3. a light source assembly; 4. a fluorescence analysis module; 5. a glass plate; 51. avoiding holes; 6. a light splitting lens.
Detailed Description
The following detailed description of the preferred embodiments of the present invention, taken in conjunction with the accompanying drawings, will make the advantages and features of the utility model easier to understand by those skilled in the art, and thus will clearly and clearly define the scope of the utility model.
Referring to fig. 1-8, a detection assembly for fluorescence analysis of a blood sample according to the present invention comprises a first body 1, a second body 2, and a spectroscopic lens 6. The first body is machined from a metallic material. The first body 1 is formed with a first inclined surface 11. The first body 1 is internally formed with a first optical path passage 14 and a second optical path passage 16. The first optical path passage 13 extends in a first direction. The second optical path passage 16 extends in the second direction. One end of the first light path channel 13 and one end of the second light path channel 16 intersect to form a first window 12 on the first slope 11. In this embodiment, the first direction is defined as being along a horizontal direction, and the second direction is defined as being along a vertical direction. The first inclined plane 11 forms an included angle of 45 degrees with the first direction and the second direction. Light may be transmitted in the first and second light path channels 14 and 14, respectively.
The second body 2 is also machined from a metallic material. The second body 2 is formed with a second inclined surface 21 corresponding to the first inclined surface 11. A third optical path passage 26 is formed in the second body 2 corresponding to the second optical path passage 16. The third optical path 26 extends in the second direction. One end of the third optical path passage 26 forms a second window 23 on the second slope 21.
The first body 1 and the second body 2 are detachably connected, and are engaged with each other and have an engaged state. In the fitted state, a mounting gap is formed between the first inclined surface 11 and the second inclined surface 21, and the first window 12 and the second window 23 correspond in the second direction, and the second optical path 16 and the third optical path 26 correspond in the second direction. The spectroscopy optics 6 is mounted in the aforementioned mounting gap and is located between the first 12 and second 23 windows. The beam splitting optics 6 are for reflecting light of a first wavelength range and for transmitting light of a second wavelength range. Wherein light of the first wavelength range is transmitted in the first light path channel 14, reflected by the beam splitter 6 and enters the second light path channel 16. The light in the second wavelength range is fluorescence generated after the blood sample is excited, and the fluorescence is transmitted in the second optical path channel 16 and enters the third optical path channel 26 after passing through the spectroscopic lens 6. In this embodiment, the wavelength range of the light in the first wavelength range is 430nm to 480nm, and the wavelength range of the light in the second wavelength range is 530nm to 600 nm. The spectroscopic lens 6 is adhered to the first inclined surface 11 or the second inclined surface 21 by a light-transmitting glue.
The detecting assembly of the present embodiment includes a light source assembly 3. The light source module 3 is adapted to emit exciting light rays which are transmitted in the first light path channel 14. The first body 1 is formed with a first side surface 13, and an end of the first light path channel 14 away from the first window 12 forms a light inlet hole on the first side surface. The light source assembly 3 is fixed on the first main body 1 and arranged corresponding to the light inlet. The light source assembly 3 is conventional in the art and is capable of generating light in the first wavelength range.
The first body 1 of this embodiment is formed with a first top surface 15. The end of the second light-path channel 16 remote from the first window 12 forms a detection hole in the first top surface 15. The light reflected by the beam splitter 6 is transmitted by the second light path channel 16, and is emitted from the detection hole to irradiate on the blood sample, so as to excite the substance of the blood sample to generate fluorescence light.
As shown in fig. 5, the first top surface 15 is covered with a light-transmissive glass plate 5. Avoidance holes 51 are processed on the glass plate 5 corresponding to the detection holes. The blood sample is placed on the glass plate 5 and the exciting light passes through the escape hole 51 and irradiates the blood sample. The glass plate 5 of the present embodiment may be replaced with other materials such as a plastic plate and a metal plate. The glass plate 5 is detachably attached to the first body 1 so that the glass plate 5 can be detached from the first body 1. Specifically, a sink groove is formed in the first top surface 15, and the glass plate 5 is fitted in the sink groove.
As shown in fig. 3, the first body 1 of the present embodiment is formed with a first insertion groove 17 for cutting off the first optical path 14. One end of the first slot 17 forms an opening on the surface of the first body 1. The first slot 17 is provided with a first filter 171 in an inserting manner. The first filter 171 is used for filtering other light rays in the first optical path 14 except the light ray in the first wavelength range. A focusing lens may be installed in the first optical path channel 14 according to actual requirements to collimate the excitation light generated by the light source assembly 3 and focus the excitation light on the beam splitting lens 6.
The detection assembly of the present embodiment includes a fluorescence analysis module 4. The second body 2 is provided with a second bottom surface 22. The end of the third light-path channel 26 remote from the second window 23 forms a light exit aperture in the second bottom surface 22. The fluorescence generated by the excited blood sample enters the second optical path channel 16, passes through the spectroscopic lens 6, enters the third optical path channel 26, and exits through the light exit hole. The fluorescence analysis module 4 is arranged corresponding to the light outlet, and the fluorescence analysis module 4 comprises a light sensor and a spectrum analysis module. The light sensor receives the light coming out of the light outlet hole, and the spectral analysis module performs spectral analysis on the light. The light sensor and the spectral analysis module are conventional components in the prior art.
Wherein the second body 2 is formed with a second slot 27 for cutting off the third optical path 26. One end of the second slot 27 forms an opening in the surface of the second body 2. The second slot 27 is provided with a second optical filter 271 in an inserting manner. The second filter 271 is used for filtering other light rays in the third optical path 26 except the light ray in the second wavelength range. According to practical requirements, a focusing lens may be installed in the third optical path channel 26 to collimate the fluorescent light transmitted in the third optical path channel 26 and focus the fluorescent light on the light sensor.
During the specific use, place the blood sample on glass board 5, produce excitation light through light source subassembly 3, this excitation light is transmitted in first light path channel 14, after reflecting through spectral lens 6, gets into in second light path channel 16 to shine to the blood sample on, in order to arouse the material production fluorescence light of blood sample. The fluorescence light enters the second light path channel 16, passes through the beam splitter 6, enters the third light path channel 26, and is received by the fluorescence analysis module 4 for spectrum analysis.
In this embodiment, the first optical path 14, the second optical path 16, and the third optical path 26 may be arranged in parallel, so as to detect substances at different positions of the blood sample.
The detection assembly of the embodiment has the advantages of compact integral structure and high integration degree, and effectively reduces the integral size of the fluorescence analysis equipment. The spectroscopic lens 6 is clamped between the first inclined surface 11 and the second inclined surface 21, so that the spectroscopic lens 6 is stable and reliable in fixation, and impurities such as dust in the air cannot contact with the spectroscopic lens, and the spectroscopic lens 6 can be effectively protected. When the glass plate 5 is worn, the glass plate 5 is replaced, so that the light can not be blocked during transmission, and the blood sample detection is facilitated.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (9)
1. A detection assembly for fluorescence analysis of a blood sample comprises a first main body, a second main body and a light splitting lens; the method is characterized in that: a first inclined plane is arranged on the first main body; a first light path channel extending along a first direction and a second light path channel extending along a second direction are arranged in the first main body; one end of the first light path channel is intersected with one end of the second light path channel on the first inclined plane to form a first window;
a second inclined plane is arranged on the second main body corresponding to the first inclined plane; a third light path channel is arranged in the second main body corresponding to the second light path channel; one end of the third light path channel forms a second window on the second inclined plane;
the first main body and the second main body are mutually matched and have a matched state; in the matched state, a mounting gap is formed between the first inclined surface and the second inclined surface, the first window and the second window correspond to each other in the second direction, and the second optical path channel and the third optical path channel correspond to each other in the second direction;
the light splitting lens is arranged in the mounting gap and positioned between the first window and the second window; the beam splitting mirror is for reflecting light of a first wavelength range and for transmitting light of a second wavelength range.
2. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: the detection assembly comprises a light source assembly; the first main body is provided with a first side surface; a light inlet hole is formed in the first side face at one end, far away from the first window, of the first light path channel; the light source component is arranged corresponding to the light inlet hole.
3. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: the first main body is provided with a first top surface; and a detection hole is formed in the first top surface at one end of the second light path channel, which is far away from the first window.
4. The detection assembly for fluorescence analysis of a blood sample according to claim 3, wherein: the first top surface is covered with a glass plate; and avoidance holes are formed in the glass plate corresponding to the detection holes.
5. The detection assembly for fluorescence analysis of a blood sample according to claim 4, wherein: the glass plate is detachably connected with the first body.
6. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: the first main body is provided with a first slot for cutting off a first light path; a first optical filter is arranged in the first slot.
7. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: and a focusing lens is arranged in the first light path channel.
8. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: the detection assembly comprises a fluorescence analysis module; a second bottom surface is arranged on the second main body; a light ray outlet hole is formed in the second bottom surface at one end, far away from the second window, of the third light path channel; the fluorescence analysis module is arranged corresponding to the light outlet.
9. The detection assembly for fluorescence analysis of a blood sample according to claim 1, wherein: a second slot for cutting off a third light path channel is arranged on the second main body; and a second optical filter is arranged in the second slot.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121119761.0U CN215985740U (en) | 2021-05-24 | 2021-05-24 | Detection assembly for fluorescence analysis of blood sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121119761.0U CN215985740U (en) | 2021-05-24 | 2021-05-24 | Detection assembly for fluorescence analysis of blood sample |
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| Publication Number | Publication Date |
|---|---|
| CN215985740U true CN215985740U (en) | 2022-03-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121119761.0U Active CN215985740U (en) | 2021-05-24 | 2021-05-24 | Detection assembly for fluorescence analysis of blood sample |
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| CN (1) | CN215985740U (en) |
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- 2021-05-24 CN CN202121119761.0U patent/CN215985740U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231025 Address after: Room 1016-A1, No. 273 Nanqiao Road, Qiongshan District, Haikou City, Hainan Province, 570100 Patentee after: Hainan Oxygen Health Medical Technology Co.,Ltd. Address before: 411100 room 725, floor 7, building 1, innovation and entrepreneurship center, No. 9, Chuanqi West Road, economic development zone, Xiangtan City, Hunan Province Patentee before: Hunan Yisheng Medical Instrument Co.,Ltd. |
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| TR01 | Transfer of patent right |