CN215962456U

CN215962456U - Continuous quick separation equipment of umbilical cord mesenchymal stem cells

Info

Publication number: CN215962456U
Application number: CN202122483253.7U
Authority: CN
Inventors: 叶翠; 高志; 万文昊
Original assignee: Chengdu Gaocuiyinhe Biotechnology Co ltd
Current assignee: Chengdu Gaocuiyinhe Biotechnology Co ltd
Priority date: 2021-10-15
Filing date: 2021-10-15
Publication date: 2022-03-08
Anticipated expiration: 2031-10-15

Abstract

The utility model discloses continuous and rapid umbilical cord mesenchymal stem cell separation equipment, which relates to the technical field of medical instruments and comprises a main body, wherein the bottom of the main body is fixedly connected with a control valve, the outer wall of the bottom of the main body is fixedly connected with supporting legs, the outer wall of one side of the main body is fixedly connected with a controller, and the inner wall of one side of the main body is fixedly connected with a supporting plate. Drive the rotor plate and rotate the post simultaneously when starting through driving motor, it slides along the inner wall that rotates the frame to rotate the post, then rotate the frame and rotate at the outer wall of fixed column, it slides along its inner wall simultaneously to rotate the frame when rotating, then the movable plate rotates thereupon, the sleeve of movable plate opposite side rotates thereupon, the connecting plate and the screening section of thick bamboo of sleeve outer wall rotate simultaneously, the in-process of screening section of thick bamboo back and forth rotation conveniently goes out its inside mesenchymal stem cell rapid segregation, and the concentrated inside that falls in the main part, the on-off control ejection of compact through the control valve, the screening effect is better, the separation efficiency of device has been improved.

Description

Continuous quick separation equipment of umbilical cord mesenchymal stem cells

Technical Field

The utility model relates to the technical field of medical instruments, in particular to continuous and rapid umbilical cord mesenchymal stem cell separation equipment.

Background

The umbilical cord mesenchymal stem cell is a multifunctional stem cell existing in umbilical cord tissues of newborns, has strong proliferation capacity and multidirectional differentiation potential, can be differentiated into hematopoietic cells under a suitable in-vivo or in-vitro environment, also has the capacity of differentiating into various cells such as muscle cells, liver cells, osteoblasts, cartilage cells, stromal cells and the like, and has wide clinical application in tissue engineering aspects such as bones, cartilages, muscles, tendons, ligaments, nerves, livers, endothelium, cardiac muscles and the like.

The conventional umbilical cord mesenchymal stem cell separation device has the following problems in use:

the separation efficiency is low and the separation effect is poor due to the inconvenient rotary separation of the device when the umbilical cord mesenchymal stem cells are separated.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide continuous and rapid umbilical cord mesenchymal stem cell separation equipment, which solves the technical problems of low separation efficiency and poor separation effect caused by inconvenient rotary separation when the equipment is used for separating umbilical cord mesenchymal stem cells.

In order to achieve the purpose, the utility model provides the following technical scheme: a continuous and rapid separation device for umbilical cord mesenchymal stem cells comprises a main body, wherein the bottom of the main body is fixedly connected with a control valve, the bottom outer wall of the main body is fixedly connected with a supporting leg, the outer wall of one side of the main body is fixedly connected with a controller, the inner wall of one side of the main body is fixedly connected with a supporting plate, the side, away from the inner wall of the main body, of the supporting plate is fixedly connected with a lower fixing ring, the top of the lower fixing ring is fixedly connected with a fixing column, the top of the fixing column is fixedly connected with an upper fixing ring, the outer wall of one side of the upper fixing ring is fixedly connected with a driving motor, the bottom of the driving motor is rotatably connected with a rotating plate, the side, away from the driving motor, of the rotating plate is fixedly connected with a rotating column, the outer wall of one side of the fixing column is rotatably connected with a rotating frame, the inner wall of the rotating frame is slidably connected with the outer wall of the rotating column, and the distance between the upper fixing ring and the lower fixing ring is larger than the height of the rotating frame, the inner wall sliding connection who rotates the frame has the removal post, the one side fixedly connected with movable plate that rotates the frame is kept away from to the removal post, one side fixedly connected with sleeve that the removal post was kept away from to the movable plate, contactless between telescopic top and the bottom of rotating the frame, telescopic outer wall fixedly connected with connecting plate, one side fixedly connected with screening section of thick bamboo that the sleeve outer wall was kept away from to the connecting plate.

Preferably, telescopic inner wall threaded connection has the screw rod, the through-hole with screw rod looks adaptation is seted up to telescopic bottom, the top fixedly connected with limiting plate of screw rod, and the size of limiting plate is greater than the size of through-hole.

Preferably, the bottom fixedly connected with spliced pole of screw rod, the outer wall fixedly connected with lifter plate of spliced pole, contactless between one side that the lifter plate kept away from the spliced pole and the inner wall of screening section of thick bamboo.

Preferably, a fixed shaft seat is fixedly connected to the inner wall of one side of the lower fixing ring, a round hole matched with the sleeve is formed in the fixed shaft seat, and the sleeve penetrates through the inside of the fixed shaft seat through the round hole and is in sliding connection with the inner wall of the round hole.

Preferably, the inner wall of one side of the screening cylinder is fixedly connected with a fixing plate below the connecting plate, and one side of the fixing plate far away from the screening cylinder is fixedly connected with a threaded ring.

Preferably, the inner wall of the threaded ring is in threaded connection with the outer wall of the screw.

Compared with the related technology, the continuous and rapid umbilical cord mesenchymal stem cell separation equipment provided by the utility model has the following beneficial effects:

1. the utility model provides continuous and rapid umbilical mesenchymal stem cell separation equipment, which is characterized in that a rotating plate and a rotating column are driven to rotate simultaneously when a driving motor is started, the rotating column slides along the inner wall of a rotating frame, the rotating frame rotates on the outer wall of a fixed column, a moving column slides along the inner wall of the rotating frame simultaneously when the rotating frame rotates, a moving plate rotates along with the rotating frame, a sleeve on the other side of the moving plate rotates along with the moving plate, a connecting plate on the outer wall of the sleeve and a screening cylinder rotate simultaneously, mesenchymal stem cells in the screening cylinder can be conveniently and rapidly separated in the process of back-and-forth rotation of the screening cylinder and fall in a main body in a centralized manner, discharging is controlled by opening and closing a control valve, the screening effect is better, the separation efficiency of a device is improved, and the separation equipment has practicability.

2. The utility model provides continuous and rapid umbilical cord mesenchymal stem cell separation equipment, which drives a screening cylinder and a fixing plate to rotate simultaneously when a sleeve rotates, a threaded ring rotates on the outer wall of a screw rod, the threaded ring and the fixing plate are fixedly arranged, and the threaded ring is in threaded connection with the screw rod, so that the screw rod can move up and down along with the threaded ring, a limiting plate slides along the inner wall of the sleeve while moving, a lifting plate can move up and down when the screw rod moves up and down, mesenchymal stem cells in the screening cylinder can be conveniently turned over up and down, the screening speed is prevented from being accumulated, the screening effect is better, and the separation efficiency of the device is improved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model.

FIG. 1 is a perspective view of the overall construction of the present invention;

FIG. 2 is a sectional view of the internal structure of the present invention;

FIG. 3 is a top perspective view of a partially cut-away construction of the present invention;

fig. 4 is a perspective view of the partially cut structure of the present invention in a bottom view.

In the figure: 1. a main body; 2. a control valve; 3. supporting legs; 4. a controller; 5. a support plate; 6. a lower fixing ring; 7. fixing a column; 8. an upper fixing ring; 9. a drive motor; 10. a rotating plate; 11. rotating the column; 12. rotating the frame; 13. moving the column; 14. moving the plate; 15. a sleeve; 16. a connecting plate; 17. a screw; 18. connecting columns; 19. a lifting plate; 20. a screening drum; 21. fixing the shaft seat; 22. a fixing plate; 23. a threaded ring.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

The first embodiment is as follows:

referring to fig. 1-4, the present invention provides a technical solution: a continuous and rapid separation device for umbilical cord mesenchymal stem cells comprises a main body 1, a control valve 2 is fixedly connected to the bottom of the main body 1, a support leg 3 is fixedly connected to the outer wall of the bottom of the main body 1, a controller 4 is fixedly connected to the outer wall of one side of the main body 1, a support plate 5 is fixedly connected to the inner wall of one side of the main body 1, a lower fixing ring 6 is fixedly connected to one side of the support plate 5 away from the inner wall of the main body 1, a fixed column 7 is fixedly connected to the top of the lower fixing ring 6, an upper fixing ring 8 is fixedly connected to the top of the fixed column 7, a driving motor 9 is fixedly connected to the outer wall of one side of the upper fixing ring 8, a rotating plate 10 is rotatably connected to the bottom of the driving motor 9, a rotating column 11 is fixedly connected to one side of the rotating plate 10 away from the driving motor 9, a rotating frame 12 is rotatably connected to the outer wall of one side of the fixed column 7, the inner wall of the rotating frame 12 is slidably connected to the outer wall of the rotating column 11, wherein, it slides along the inner wall that rotates frame 12 to rotate post 11 convenience, the distance between upper fixed ring 8 and the lower fixed ring 6 is greater than the height size that rotates frame 12, wherein, it makes things convenient for last fixed ring 8 and the lower fixed ring 6 to make a round trip to rotate frame 12, the inner wall sliding connection who rotates frame 12 has removal post 13, remove one side fixedly connected with movable plate 14 that frame 12 was kept away from to post 13, one side fixedly connected with sleeve 15 that removal post 13 was kept away from to movable plate 14, contactless between the top of sleeve 15 and the bottom that rotates frame 12, wherein, it conveniently rotates frame 12, and also can not cause the hindrance when rotating sleeve 15 top, sleeve 15's outer wall fixedly connected with connecting plate 16, one side fixedly connected with screening section of thick bamboo 20 that sleeve 15 outer wall was kept away from to connecting plate 16.

In this embodiment, drive rotor plate 10 and rotation post 11 and rotate simultaneously when starting up through driving motor 9, rotation post 11 slides along the inner wall that rotates frame 12, then rotate frame 12 and rotate at the outer wall of fixed column 7, it slides along its inner wall simultaneously to rotate removal post 13 when frame 12 rotates, then movable plate 14 rotates thereupon, sleeve 15 of movable plate 14 opposite side rotates thereupon, the connecting plate 16 and the screening section of thick bamboo 20 of sleeve 15 outer wall rotate simultaneously, screening section of thick bamboo 20 makes things convenient for the mesenchymal stem cell rapid segregation of its inside back and forth rotation's in-process, and concentrate the inside that falls in main part 1, the switch control ejection of compact through control valve 2, the screening effect is better, the separation efficiency of device has been improved, and the practicality is possessed.

Example two:

referring to fig. 1-4, on the basis of the first embodiment, the present invention provides a technical solution: the inner wall of the sleeve 15 is in threaded connection with a screw rod 17, the bottom of the sleeve 15 is provided with a through hole matched with the screw rod 17, the top of the screw rod 17 is fixedly connected with a limiting plate, and the size of the limiting plate is larger than that of the through hole, wherein the limiting plate is arranged to prevent the screw rod 17 from being separated from the sleeve 15 when rotating, the limiting effect is better, the bottom of the screw rod 17 is fixedly connected with a connecting column 18, the outer wall of the connecting column 18 is fixedly connected with a lifting plate 19, one side of the lifting plate 19, which is far away from the connecting column 18, is not contacted with the inner wall of a sieving cylinder 20, wherein the lifting plate 19 cannot collide with the inner wall of the sieving cylinder 20 when moving back and forth up and down, the up and down movement is convenient, the inner wall of one side of the lower fixing ring 6 is fixedly connected with a fixing shaft seat 21, the inside of the fixing shaft seat 21 is provided with a round hole matched with the sleeve 15, and the sleeve 15 penetrates through the inside of the round hole and is in sliding connection with the inner wall of the round hole, wherein, fixed axle bed 21 has played the spacing effect of sleeve 15, the setting of round hole is for making things convenient for sleeve 15's rotation, one side inner wall of screening section of thick bamboo 20 and the below fixedly connected with fixed plate 22 that is located connecting plate 16, one side fixedly connected with screw ring 23 of screening section of thick bamboo 20 is kept away from to fixed plate 22, the inner wall of screw ring 23 and the outer wall threaded connection of screw rod 17, wherein, screw rod 17 rotates along screw ring 23's inner wall along with sleeve 15 pivoted in, thereby make things convenient for reciprocating of screw rod 17.

In this embodiment, drive screening section of thick bamboo 20 and fixed plate 22 and rotate simultaneously when rotating through sleeve 15, threaded ring 23 rotates at screw rod 17's outer wall, because threaded ring 23 and fixed plate 22 are fixed the setting, threaded ring 23 is threaded connection with screw rod 17, therefore screw rod 17 can reciprocate thereupon, and the limiting plate slides along sleeve 15's inner wall when removing, lifter plate 19 can realize reciprocating when screw rod 17 reciprocates, conveniently overturn from top to bottom the inside mesenchymal stem cell of screening section of thick bamboo 20, prevent to pile up screening speed once, the screening effect is better, the separation efficiency of device has been improved.

The working principle is as follows:

when the device is used, firstly, the rotating plate 10 and the rotating column 11 are driven to rotate simultaneously when the driving motor 9 is started, the rotating column 11 slides along the inner wall of the rotating frame 12, then the rotating frame 12 rotates on the outer wall of the fixed column 7, the moving column 13 slides along the inner wall of the rotating frame 12 simultaneously when the rotating frame 12 rotates, then the moving plate 14 rotates along with the moving plate, the sleeve 15 on the other side of the moving plate 14 rotates along with the moving plate, the connecting plate 16 on the outer wall of the sleeve 15 and the sieving cylinder 20 rotate simultaneously, mesenchymal stem cells in the sieving cylinder 20 can be conveniently and rapidly separated in the back-and-forth rotating process and fall in the main body 1 in a centralized manner, discharging is controlled through the switch of the control valve 2, the sieving effect is better, the separation efficiency of the device is improved, and the practicability is achieved;

finally, drive screening section of thick bamboo 20 and fixed plate 22 and rotate simultaneously when rotating through sleeve 15, threaded ring 23 rotates at screw rod 17's outer wall, because threaded ring 23 and fixed plate 22 are fixed the setting, threaded ring 23 is threaded connection with screw rod 17, therefore screw rod 17 can reciprocate thereupon, and the limiting plate slides along sleeve 15's inner wall when removing, lifter plate 19 can realize reciprocating when screw rod 17 reciprocates, conveniently overturn from top to bottom the mesenchymal stem cell of screening section of thick bamboo 20 inside, prevent to pile up screening speed once, the screening effect is better, the separation efficiency of device has been improved.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides a continuous quick separation equipment of umbilical cord mesenchymal stem cell, includes main part (1), its characterized in that: the bottom of the main body (1) is fixedly connected with a control valve (2), the bottom outer wall of the main body (1) is fixedly connected with a supporting leg (3), one side outer wall of the main body (1) is fixedly connected with a controller (4), one side inner wall of the main body (1) is fixedly connected with a supporting plate (5), one side, far away from the inner wall of the main body (1), of the supporting plate (5) is fixedly connected with a lower fixing ring (6), the top of the lower fixing ring (6) is fixedly connected with a fixing column (7), the top of the fixing column (7) is fixedly connected with an upper fixing ring (8), one side outer wall of the upper fixing ring (8) is fixedly connected with a driving motor (9), the bottom of the driving motor (9) is rotatably connected with a rotating plate (10), one side, far away from the driving motor (9), of the rotating plate (10) is fixedly connected with a rotating column (11), the utility model discloses a screening machine, including fixed column (7), one side outer wall of fixed column (7) rotates and is connected with rotation frame (12), the inner wall of rotation frame (12) and the outer wall sliding connection who rotates post (11), distance between upper fixed ring (8) and lower fixed ring (6) is greater than the height of rotating frame (12), the inner wall sliding connection who rotates frame (12) has removal post (13), one side fixedly connected with movable plate (14) of rotating frame (12) are kept away from to removal post (13), one side fixedly connected with sleeve (15) of removing post (13) are kept away from in movable plate (14), contactless between the top of sleeve (15) and the bottom of rotating frame (12), the outer wall fixedly connected with connecting plate (16) of sleeve (15), one side fixedly connected with screening section of thick bamboo (20) of sleeve (15) outer wall are kept away from in connecting plate (16).

2. The continuous and rapid umbilical cord mesenchymal stem cell separation device according to claim 1, wherein: the inner wall threaded connection of sleeve (15) has screw rod (17), the through-hole with screw rod (17) looks adaptation is seted up to the bottom of sleeve (15), the top fixedly connected with limiting plate of screw rod (17), and the size of limiting plate is greater than the size of through-hole.

3. The continuous and rapid umbilical cord mesenchymal stem cell separation device according to claim 2, wherein: the bottom fixedly connected with spliced pole (18) of screw rod (17), the outer wall fixedly connected with lifter plate (19) of spliced pole (18), contactless between one side that the spliced pole (18) was kept away from in lifter plate (19) and the inner wall of screening section of thick bamboo (20).

4. The continuous and rapid umbilical cord mesenchymal stem cell separation device according to claim 1, wherein: the inner wall of one side of the lower fixing ring (6) is fixedly connected with a fixing shaft seat (21), a round hole matched with the sleeve (15) is formed in the fixing shaft seat (21), and the sleeve (15) penetrates through the inside of the fixing shaft seat (21) through the round hole and is in sliding connection with the inner wall of the round hole.

5. The continuous and rapid umbilical cord mesenchymal stem cell separation device according to claim 1, wherein: the screening section of thick bamboo (20) just is located below fixedly connected with fixed plate (22) of connecting plate (16) on one side inner wall, one side fixedly connected with screw ring (23) of screening section of thick bamboo (20) are kept away from in fixed plate (22).

6. The continuous and rapid umbilical cord mesenchymal stem cell separation device according to claim 5, wherein: the inner wall of the threaded ring (23) is in threaded connection with the outer wall of the screw (17).