CN215960584U - Dosage control assembly and syringe - Google Patents

Abstract

The utility model discloses a dose control assembly and an injector, wherein the dose control assembly comprises a booster and a stroke limiting device matched with the booster, the booster enables a push rod to push a piston along a hollow sleeve to move in one direction only towards the far end of a medicine volume chamber in the medicine volume chamber, the push rod is removably engaged with the hollow sleeve of the booster, and the stroke of the push rod for pushing the piston to move in parallel in the medicine volume chamber through the booster is controlled. Wherein the travel limiting device mainly comprises a combining part which is removably jointed with the hollow sleeve of the booster; the near end of the combining part is provided with a dosage boss, the near end of the dosage boss protrudes inwards and is clamped into a gap between the near end of the hollow sleeve of the booster and the near end of the push rod, and the height of the protrusion of the dosage boss is the stroke of the push rod for pushing the piston to move in the medicine volume chamber in parallel along the booster; the height of the projection of the dosage boss can be adjusted according to the size of the injector and the required dosage to meet different dosage requirements.

Description

Dosage control assembly and syringe

Technical Field

The present invention relates to medical devices, and more particularly to dose control assemblies and syringes.

Background

In clinical applications, it is often necessary to inject small quantities of a drug in a precise dose into a patient. Herein, a small amount of medication means that the volume of medication to be injected into a patient is less than 5%, 10%, 15% or 20% of the total volume of the syringe. For example, in the treatment of ophthalmic diseases (such as macular degeneration of the retina, vitreous opacity, etc.), medical personnel are required to inject a small amount of a drug in a precise dose into the eye site of a patient.

Conventional syringes typically consist of a drug volume chamber at the front end and a matching plunger with a plunger, the rear end of the drug volume chamber typically being flanged for grasping by the user. Because the syringe is generally smaller in volume, the flange part at the tail part of the medicine volume chamber is difficult to grasp by hands in actual operation, so that the difficulty is brought to clinical application, the labor intensity of medical workers is greatly increased, and the injection precision is reduced. To provide a precise injected dose, prior injectors typically set a dose indicator line on the outer wall of the medication volume chamber, and the healthcare worker provides the patient with the required injected dose by aligning a specific location of the push rod with a pre-set dose indicator line on the medication volume chamber during use. However, such operation is often not well implemented in practical applications, such as: medical personnel are difficult to accurately correspond the push rod to the dose indication set on the medicine volume chamber due to upward or downward visual errors and the like, so that the requirement of accurate medicine administration cannot be met. Especially for small volume syringes, such as ophthalmic syringes, in which about 100 μ L or less of liquid is to be injected, slight errors in the calibration of the dose indication on the specific part of the plunger and the drug volume chamber are likely to result in large variations in the injected dose, which in the past would be a potential clinical risk.

Particularly for a pre-filled syringe, the medicine is usually pre-filled and sealed in a medicine volume chamber of the syringe, then plugging, light inspection, sterilization and other operations are carried out, and medical staff only need to empty and administer the medicine when using the syringe; at this time, if the medical staff pulls the push rod due to operation error, unclean air may be sucked into the medicine volume chamber, which causes pollution to the sterile preparation; in addition, in the process of vacuum sterilization or transportation of the prefilled syringe, the liquid in the drug volume chamber may be unexpectedly deformed or moved due to the influence of pressure, so that the sterile environment of prefilled drugs in the syringe and the accurate control of injection dosage are adversely affected.

Disclosure of Invention

The utility model aims to provide a dosage control assembly and an injector which are convenient for medical staff to use and can accurately control the injection dosage, so as to overcome the defects in the prior art.

The present invention provides in one aspect a dose control assembly for accurately controlling the injection of a dose of medicament by an injector comprising a medicament volume chamber and a push rod and piston axially movable within the medicament volume chamber, the dose control assembly comprising:

the booster mainly comprises a clamping part, and the far side of the clamping part is provided with an opening to clamp the near end of the medicine volume chamber; a hollow sleeve disposed proximal to the grip, the hollow sleeve configured to be coaxial with the medication volume such that the push rod pushes the piston along the hollow sleeve to move the piston within the medication volume in only one direction toward the distal end of the medication volume to deliver at least a portion of the substance within the medication volume to the needle;

and a travel stop mated with the booster, the travel stop configured to removably engage the booster hollow sleeve, controlling travel of the push rod to push a piston through the booster to move in parallel within the medication volume chamber.

The booster clamping part is composed of a push rod fixing groove and side wings symmetrically arranged on two sides of the fixing groove, and the hollow sleeve is configured to be connected with the fixing groove and extend towards the far end of the medicine volume chamber; the push rod fixing groove is provided with an opening at one side and can be parallelly clamped on a flange at the near end of the medicine volume chamber from the side; the inner diameter of the hollow sleeve is matched with the outer diameter of the push rod, so that the push rod can move in the hollow sleeve in parallel.

The stroke limiting device mainly comprises a combination part, and the combination part is removably jointed with the hollow sleeve of the booster; the near end of the combining part is provided with a dosage boss, the near end of the dosage boss protrudes inwards and is clamped into a gap between the near end of the hollow sleeve of the booster and the near end of the push rod, and the height of the protrusion of the dosage boss is the stroke of the push rod for pushing the piston to move in the medicine volume chamber in parallel along the booster; the height of the projection of the dosage boss can be adjusted according to the size of the injector and the required dosage to meet different dosage requirements.

Furthermore, the stroke limiting device is provided with an empennage for controlling the opening and closing of the joint part of the stroke limiting device, and the joint part of the stroke limiting device is provided with an opening at one side and can be parallel to the side surface and clamped on the hollow sleeve of the booster through the empennage; the outer diameter of the hollow sleeve is matched with the inner diameter of the joint part of the stroke limiting device; the two sides of the opening of the stroke limiting device combining part are provided with clamping parts used for clamping the hollow sleeve of the booster, and the clamping parts are configured to be inwards convex.

Furthermore, a clamping pin is arranged at the joint part of the stroke limiting device, and a groove is arranged on the outer wall of the hollow sleeve and is meshed with the clamping pin of the stroke limiting device.

Furthermore, the stroke limiting device combining part is provided with a metal part, the outer wall of the hollow sleeve is provided with a magnet which is matched with the stroke limiting device metal part to generate magnetic attraction, and the stroke limiting device combining part can be fixed on the hollow sleeve of the booster in an adsorption mode from the side surface in parallel and through the tail wing.

And a sawtooth clamping groove is formed in the inner wall of the hollow sleeve of the booster and is meshed with a clamping tooth arranged on the push rod, so that the push rod moves towards the far end of the medicine volume chamber in the hollow sleeve of the booster in one direction.

Furthermore, the far end of the push rod is provided with a stopping piece, and the stopping piece is fully contacted with the surface of the near end of the piston, so that the piston is uniformly stressed.

According to another aspect of the utility model, the utility model relates to a dose control syringe for injecting precise doses of small amounts of a medicament, the syringe comprising: comprises a medicine volume chamber, a push rod and a piston which can move axially in the medicine volume chamber; and a dose control assembly according to the above aspect.

The piston is a coated rubber plug; the drug containment chamber is pre-filled with a volume of a drug solution containing a pharmaceutically active substance.

Compared with the prior art, the injector of the utility model has the following advantages:

1. the utility model provides a comfortable acting point for medical care personnel for the contact part of a user, is convenient for pressing operation, reduces the labor intensity and improves the injection efficiency;

2. the utility model can provide accurate injection dosage, does not need medical staff to carry out manual calibration, and avoids dosage deviation caused by visual error;

3. the utility model effectively prevents the syringe piston from moving backwards caused by vacuum sterilization or manual operation errors, and reduces the possibility of liquid medicine pollution;

4. the utility model has simple structure and low cost, and is suitable for industrial application.

Drawings

FIG. 1 is a perspective view of a dose control assembly

FIG. 2 is a perspective view of the booster

FIG. 3 is a schematic view of a structure of a limiting device for a wrapping and clamping stroke

FIG. 4 is a schematic view of a dose control assembly with a recessed clip

FIG. 5A-B of FIG. 4 showing a grooved booster

Fig. 6 a-B of the stroke limiter with a clamping foot as shown in fig. 4

FIG. 7 is a schematic view of a dose control assembly with a magnetic component

FIG. 8A-B of the booster with magnet assembly shown in FIG. 7

FIG. 9A-B of the stroke limiter with metal parts shown in FIG. 7

FIG. 10 is a schematic view of a dose control assembly with an anti-backup assembly

FIG. 11 is a schematic view of a booster with sawtooth slots

FIG. 12 is an enlarged schematic cross-sectional view of a booster with sawtooth slots

FIG. 13 is the push rod with latch shown in FIG. 10

FIG. 14 is a schematic illustration of a pre-filled syringe with a push rod with a stopper, a booster, and a dose control assembly:

1. dosage control assembly, 11 booster, 111 clamping part, 112 hollow sleeve, side wing 113, groove 114, magnet part 115, sawtooth clamping groove 116, stroke limiting device 12, combination part 121, dosage boss 122, tail wing 123, rib 124, clamping foot 125 and metal part 126

2. Medication containment chamber

3. Push rod, 31 latch, 32 stop

4. Piston

Detailed Description

The following description of the embodiments of the present invention will be made with reference to the accompanying drawings.

Herein, the term "distal end" refers to the portion that is described as being further from the user, while the term "proximal end" refers to the portion that is described as being closer to the user.

Example 1:

the present embodiment provides a dose control assembly 1, as shown in figures 1-3: the dose control assembly is for accurately controlling a small dose of medicament injected by an injector comprising a medicament volume chamber 2 and a plunger 3 and piston 4 axially movable within the medicament volume chamber, the dose control assembly 1 comprising:

the booster 11 mainly comprises a clamping part 111, and the far side of the clamping part 111 is provided with an opening to clamp the near end of the medicine volume chamber 2; and a hollow sleeve 112 disposed proximal to the grip 111, the hollow sleeve 112 being configured to be coaxial with the medication volume 2 such that the plunger 3 pushes the piston 4 along the hollow sleeve 112 to move in parallel within the medication volume 2 to deliver at least a portion of the substance within the medication volume 2 to the needle;

and a travel stop 12 matching the booster 11, the travel stop 121 being configured to removably engage the hollow sleeve 112 of the booster 11, controlling the travel of the push rod 3 to push the piston 4 through the booster 11 in parallel movement within the medicament volume chamber 2.

Wherein the grip portion 111 of the booster 11 is provided with a push rod fixing groove, and the hollow sleeve 112 is configured to be connected with the fixing groove and extend to the distal end of the medicine volume chamber 2; the push rod fixing groove is provided with an opening at one side and can be parallelly clamped on a flange at the near end of the medicine volume chamber 2 from the side; the inner diameter of the hollow sleeve 112 is matched to the outer diameter of the push rod 3, so that the push rod 3 can move in parallel in the hollow sleeve 112.

When the flanks 113 arranged on the two symmetrical sides of the booster clamping part 111 are used, medical personnel can conveniently grasp the flanks 113 on the two sides of the booster during injection operation, and the wing-shaped, arc-shaped and other suitable-shaped flank 113 structures provide comfortable force points for the fingers of the medical personnel, so that the medical personnel can operate more simply and more easily, and the injection efficiency is effectively improved.

Wherein, the stroke limiting device 12 mainly comprises a combining part 121, and the combining part 121 is removably jointed with the hollow sleeve 112 of the booster; a dosage boss 122 is arranged at the proximal end of the combining part 121, the proximal end of the dosage boss 122 protrudes inwards and is clamped into a gap between the proximal end of the hollow sleeve 112 of the booster and the proximal end of the push rod 3, and the protruding height of the dosage boss 122 is a stroke of the push rod 3 for pushing the piston to move in parallel in the medicine volume chamber 2 through the booster 11; the height of the projection of the dose projection 122 can be adjusted according to the size of the medicament volume chamber 2 and the required dose to be administered, so as to meet different administration requirements.

In this embodiment, the joint portion 121 of the stroke limiting device 12 is provided with a tail wing 123 for controlling the joint portion 121 of the stroke limiting device 12 to open and close, and the joint portion 121 of the stroke limiting device 12 is provided with an opening at one side and can be parallel from the side and clamped on the hollow sleeve 112 of the booster 11 through the tail wing 123; the outer diameter of the hollow sleeve 112 is matched with the inner diameter of the stroke limiting device combining part 121, so that the stroke limiting device combining part 121 is attached to the hollow sleeve 112, and the stroke limiting device combining part 121 is prevented from sliding on the hollow sleeve 112. Before the medical staff finishes the injection action, the tail wings 123 clamp the stroke limiting device combining part 121 on the hollow sleeve 112 of the booster, then the liquid taking, the emptying and other steps are carried out, the proximal end part of the push rod 3 is pushed to the position of the dosage boss 122 after the emptying step is finished, then the two tail wings 123 of the stroke limiting device combining part 121 are respectively pressed by the thumb and the forefinger, the stroke limiting device 12 is parallelly taken down from the hollow sleeve 112, then the piston 4 is pushed to the far end edge position of the medicine volume chamber 2 by pushing the push rod 3, at least one part of substances in the medicine volume chamber 2 is injected into human tissues through the needle head, and the injection can be finished. In practical use, a plurality of ribs may be respectively disposed on the two tail fins 123 of the coupling portion 121 of the stroke limiting device 12 according to requirements to increase the friction between the tail fins 123 and the fingers, so as to prevent slipping. The dose control assembly 1 of the present embodiment provides a precise injection dose by tightly controlling the protrusion height of the dose boss 122.

Wherein, the opening both sides of stroke stop device 12 joint 121 are equipped with clamping part 124, clamping part 123 is inwards protruding, is convenient for strengthen the package clamp power of stroke stop device 12 joint 121 makes stroke stop device 12 joint 121 grasps hollow sleeve 112 outer wall of boost, thereby avoids stroke stop device 12 joint 121 slides on hollow sleeve 112 outer wall, influences accurate injection dosage.

In this embodiment, the tail 123 may further be provided with a rib 124, so that when a medical staff applies a clamping force to the tail 123, the fingers are prevented from sliding on the tail 123. In order to provide a more comfortable and stable point of attack.

Example 2:

in this embodiment, on the basis of the dosage control assembly 1 described in embodiment 1, there is further provided a dosage control assembly 1, as shown in fig. 4-6, the engaging portion 121 of the stroke limiting device 12 is provided with a locking pin 125, and the outer wall of the hollow sleeve 112 is provided with a groove 114 to engage with the locking pin 125 of the stroke limiting device engaging portion 121, so as to prevent the stroke limiting device 12 from moving axially on the hollow sleeve 112, which results in the dosage boss 122 not accurately controlling the stroke of the push rod 3 pushing the piston 4 along the booster 11 to move in parallel in the medicine volume chamber 2, thereby reducing the precision of the injected dosage.

Wherein, the far ends of the two sides of the opening of the stroke limiting device combining part 121 are respectively provided with a clamping pin 125, so that the effect is better.

Example 3:

in this embodiment, on the basis of the dosage control assembly 1 described in embodiment 1, there is further provided a dosage control assembly 1, as shown in fig. 7-9, the stroke limiting device combining part 121 is provided with a metal component 126, the outer wall of the hollow sleeve 112 is provided with a magnet component 115, and the metal component 126 of the stroke limiting device combining part 121 generates magnetic force, which can be fixedly attached to the hollow sleeve 112 of the booster from the side surface in parallel via the tail wing 123.

In this embodiment, the metal member is an annular metal member disposed at the distal bottom of the stroke limiter coupling portion 121, and an annular magnet member 115 is disposed on the outer wall of the hollow sleeve 112 at a position opposite to the distal bottom of the stroke limiter coupling portion 121.

This embodiment also can be through the metal strip is set up respectively to stroke stop device joint portion 121 opening both sides, the hollow sleeve outer wall be equipped with magnet part 115 with the metal strip of stroke stop device joint portion distal end produces magnetic force, also can with stroke stop device 12 is fixed to be adsorbed the boost motor on the hollow sleeve 112, avoid stroke stop device 12 is in axial displacement leads to on the hollow sleeve 112 dose boss 122 can't accurate control the push rod via boost motor 11 promotes piston 4 and is in parallel movement's stroke in the medicine volume room 2 reduces the accurate of injection dose.

Example 4:

this embodiment further provides a dose control assembly 1 based on the dose control assembly 1 of embodiment 1, as shown in fig. 10-10, wherein the hollow sleeve 112 of the booster 11 is further provided with serrated slots 116 on the inner wall thereof, and the serrated slots 116 are matched with the resilient latches 31 provided on the plunger 3 of the syringe, so that the plunger 3 can only move in the direction towards the distal end of the drug volume chamber 2 but not in the direction away from the distal end of the drug volume chamber 2 within the hollow sleeve 112 of the booster.

When the hollow sleeve 112 of the booster is used for pre-filling and sealing the syringe, a plurality of sawtooth clamping grooves 116 can be further arranged in the hollow sleeve 112 of the booster, and meanwhile, the push rod 3 is provided with the elastic clamping teeth 31 which can be matched with the sawtooth clamping grooves 116. In practice, the medicine is generally filled into the medicine volume chamber 2 of the syringe, then the booster 11 and the push rod 3 are loaded onto the medicine volume chamber 2, the travel limiter coupling portion 121 is fixed on the hollow sleeve 112, the push rod 3 is pushed to make the latch 31 and the sawtooth slot 116 in the hollow sleeve 112 form a toothed engagement structure, and the proximal end of the push rod 3 and the dosage boss 122 are kept at a predetermined emptying distance for the medical staff to perform the emptying operation during use, the toothed engagement structure enables the distal end of the push rod 3 to push the plunger 4 to move in the medicine volume chamber 2 only in a direction towards the distal end of the medicine volume chamber 2 but not in a direction away from the medicine volume chamber 2.

In the embodiment, the sawtooth clamping groove 116 and the clamping teeth 31 form a close occlusion structure, the two are tightly and firmly fitted, and are not easy to separate due to the action of external force, so that the piston can not move backwards due to the expansion of the volume of liquid in the medicine volume chamber in the vacuum sterilization process, and the possibility of medicament pollution is avoided; meanwhile, when the medical care personnel use, the medical care personnel can prevent the liquid medicine pollution caused by that unclean air is sucked into the needle cylinder due to misoperation, and better guarantee is provided for clinic.

The far end of the push rod 3 is provided with a stop member 32, and the stop member 32 is matched with the sawtooth clamping groove 116 of the booster 11 and the clamping teeth 31 of the push rod 3 and is always in full contact with the surface of the near end of the piston 4, so that the piston 4 is uniformly stressed. With 4 near-end surfaces of piston fully contact, with this embodiment 11 cooperations of boost motor can prevent in vacuum sterilization or transportation piston 4 to 2 distal end directions in medicine volume room produce irregular deformation because of pressure or temperature variation, destroy the sterile environment of liquid medicine leads to the medicament pollution in the medicine volume room 2, can be at the injection in-process again, make 4 near-end surfaces of piston evenly receive the force, avoid piston 4 reduces the accuracy of injection dosage because of the inhomogeneous irregular deformation that produces of atress.

Example 5:

this embodiment, in combination with the above embodiments 1-4, is a dose control syringe for injecting precise doses of small amounts of medication as illustrated in figure 11, the syringe comprising: comprises a medicine volume chamber 2, a push rod 3 and a piston 4 which can move axially in the medicine volume chamber; and a dose control assembly 1 as described in embodiments 1-4.

Wherein, the piston 4 is a coated rubber plug.

The drug containment chamber of the present embodiment contains a drug solution of one or more pharmaceutically active substances selected from the group consisting of antibodies, antiviral agents, chemotherapeutic agents, analgesics, anesthetics, aptamers, antihistamines, anti-inflammatory agents, and antineoplastic agents.

In this embodiment, the syringe may be pre-filled with a drug solution containing a pharmaceutically active substance in a pre-packaging manner into the drug volume chamber of the syringe, or may be configured to draw at least a portion of the drug solution containing the pharmaceutically active substance from a drug reservoir such as a vial into the drug volume chamber.

The embodiments of the present invention are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same or similar parts in each embodiment are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.

The dosage control assembly and syringe provided by the present invention have been described in detail above. The principles and embodiments of the present invention are explained herein using specific examples, which are presented only to assist in understanding the method and its core concepts. It should be noted that, for those skilled in the art, it is possible to make various improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the scope of the claims of the present invention.

Claims (10)

1. A dose control assembly for precisely controlling the injection of a dose of medication by an injector, the injector comprising a medication volume chamber and a push rod and piston axially movable within the medication volume chamber, the dose control assembly comprising:

the booster mainly comprises a clamping part, and the far side of the clamping part is provided with an opening to clamp the near end of the medicine volume chamber; a hollow sleeve disposed proximal to the grip, the hollow sleeve configured to be coaxial with the medication volume such that the push rod pushes the piston along the hollow sleeve to move the piston within the medication volume in only one direction toward the distal end of the medication volume to deliver at least a portion of the substance within the medication volume to the needle;

and a travel stop mated with the booster, the travel stop configured to removably engage the booster hollow sleeve, controlling travel of the push rod to push a piston through the booster to move in parallel within the medication volume chamber.

2. The dose control assembly of claim 1, wherein the booster grip is comprised of a push rod retaining slot, side wings symmetrically disposed on either side of the retaining slot, the hollow sleeve configured to connect to the retaining slot and extend distally of the drug volume chamber; the push rod fixing groove is provided with an opening at one side and can be parallelly clamped on a flange at the near end of the medicine volume chamber from the side; the inner diameter of the hollow sleeve is matched with the outer diameter of the push rod, so that the push rod can move in the hollow sleeve in parallel.

3. The dose control assembly of claim 1, wherein the travel stop essentially comprises a junction that removably engages with a hollow sleeve of the booster; and the joint portion near-end is equipped with the dosage boss, dosage boss near-end is inside protruding to go into with hollow sleeve near-end of booster with clearance between the push rod near-end, the protruding height of dosage boss does the push rod is followed the booster promotes the piston and is in the indoor parallel movement's of medicine volume stroke.

4. The dosage control assembly according to claim 3, wherein the stroke limiting device is provided with a tail wing for controlling the opening and closing of the stroke limiting device combining part, and the stroke limiting device combining part is provided with an opening at one side and can be clamped on the hollow sleeve of the booster from the side in parallel and through the tail wing; the outer diameter of the hollow sleeve is matched with the inner diameter of the joint part of the stroke limiting device; the two sides of the opening of the stroke limiting device combining part are provided with clamping parts used for clamping the hollow sleeve of the booster, and the clamping parts are configured to be inwards convex.

5. The dose control assembly of claim 4, wherein said travel stop interface is provided with a detent, and said hollow sleeve outer wall is provided with a groove for engaging said travel stop interface detent.

6. The dosage control assembly of claim 4, wherein the stroke limiting device combining part is provided with a metal part, the outer wall of the hollow sleeve is provided with a magnet which is matched with the stroke limiting device metal part to generate magnetic attraction, and the stroke limiting device combining part can be fixed on the hollow sleeve of the booster in an adsorption manner from the side surface in parallel and through the tail wing.

7. The dose control assembly of claim 1, wherein the hollow sleeve of the booster has serrated slots formed in an inner wall thereof, the serrated slots engaging with teeth formed on the push rod to allow unidirectional movement of the push rod within the hollow sleeve of the booster to the distal end of the drug volume chamber.

8. The dosage control assembly of claim 7, wherein the distal end of the push rod is provided with a stop member, and the stop member is always in full contact with the surface of the proximal end of the piston under the matching of a sawtooth clamping groove of the booster and a clamping tooth of the push rod, so that the piston is uniformly stressed.

9. An injector for injecting precise doses of a medicament, comprising a medicament volume chamber and a plunger and piston axially movable within the medicament volume chamber; and a dose control assembly according to any one of claims 1 to 8.

10. The syringe of claim 9, wherein the piston is a coated rubber plug; the drug containment chamber is pre-filled with a volume of a drug solution containing a pharmaceutically active substance.

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