CN215914865U - High voltage generating circuit for catheter and ablation tool - Google Patents
High voltage generating circuit for catheter and ablation tool Download PDFInfo
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- CN215914865U CN215914865U CN202121864303.XU CN202121864303U CN215914865U CN 215914865 U CN215914865 U CN 215914865U CN 202121864303 U CN202121864303 U CN 202121864303U CN 215914865 U CN215914865 U CN 215914865U
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Abstract
The utility model discloses a high voltage generating circuit and an ablation tool for a catheter, wherein the high voltage generating circuit comprises: the input ends of the N voltage conversion units are connected in parallel and then connected with the total input end of the high-voltage generating circuit, the output ends of the N voltage conversion units are connected in series and then connected with the total output end of the high-voltage generating circuit, and the N energy storage units correspond to the N voltage conversion units one to one; the output ends of the N voltage conversion units are connected in series and then are connected with the total output end through the current adjusting unit; the control unit is connected with the N voltage conversion units and the current adjusting unit and used for controlling the N voltage conversion units and the current adjusting unit so as to adjust the output voltage and the output current of the total output end. Therefore, the rapid switching of different output powers can be realized, and the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved.
Description
Technical Field
The utility model relates to the technical field of pulsed electric field ablation, in particular to a high-voltage generating circuit for a catheter and an ablation tool.
Background
The ablation energy in the catheter ablation technology adopted for treating arrhythmia at present is mainly radio frequency energy and is assisted by freezing energy, and the two ablation modes have certain superiority in treating arrhythmia and have corresponding limitations, for example, the ablation energy has no selectivity for damaging tissues in an ablation area, and certain damage can be caused to adjacent esophagus, coronary artery, phrenic nerve and the like depending on the adhesion force of a catheter, so that the related technology of finding a quick, safe and efficient ablation energy to complete and achieve persistent pulmonary vein isolation without damaging adjacent tissues becomes a hotspot of research.
Pulsed electric field ablation is a new type of ablation using pulsed electric field as energy, and is gaining attention as a non-thermal ablation technique in clinical application. The pulsed electric field ablation technology is mainly characterized in that a high-voltage pulsed electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, extremely high energy is released in a short time, and a cell membrane, even intracellular organelles such as endoplasmic reticulum, mitochondria, cell nucleus and the like can generate a large number of irreversible micropores, so that apoptosis of pathological cells is caused, and the expected treatment purpose is achieved. However, as a new energy ablation technology, the pulsed electric field ablation technology faces the defect that the output power of the high voltage generating circuit cannot be rapidly switched, so that the clinical application of the pulsed electric field ablation technology is limited.
SUMMERY OF THE UTILITY MODEL
The present invention is directed to solving, at least to some extent, one of the technical problems in the related art. Therefore, the first objective of the present invention is to provide a high voltage generating circuit for a catheter, which can realize fast switching of different output powers through a plurality of voltage converting units and current adjusting units, and the adopted components are small, thereby improving the application prospect of the pulsed electric field ablation technology in arrhythmia treatment.
A second object of the utility model is to propose an ablation instrument.
In order to achieve the above object, a first embodiment of the present invention provides a high voltage generating circuit for a catheter, including: the input ends of the N voltage conversion units are connected with the total input end of the high-voltage generating circuit after being connected in parallel, the output ends of the N voltage conversion units are connected with the total output end of the high-voltage generating circuit after being connected in series, the N energy storage units correspond to the N voltage conversion units one by one, each energy storage unit is connected between the output ends of the corresponding voltage conversion units, each voltage conversion unit in the N voltage conversion units is used for performing voltage conversion on the input voltage of the total input end and charging the corresponding energy storage unit, and N is an integer greater than 1; the output ends of the N voltage conversion units are connected in series and then are connected with the total output end through the current adjustment unit so as to adjust the output current of the total output end; and the control unit is connected with the N voltage conversion units and the current adjusting unit and is used for controlling the N voltage conversion units and the current adjusting unit so as to adjust the output voltage and the output current of the total output end.
According to the high-voltage generating circuit for the catheter, the input end of the voltage conversion unit is connected with the total input end of the high-voltage generating circuit after being connected in parallel, the output end of the voltage conversion unit is connected with the total output end through the current adjusting unit after being connected in series, the control unit controls the voltage conversion unit and the current adjusting unit to adjust the output voltage and the output current of the total output end, the rapid switching of different output powers can be achieved, the adopted components are small, and the application prospect of the pulse electric field ablation technology in arrhythmia treatment is improved.
According to one embodiment of the present invention, the control unit includes one or more control chips, wherein, when the control unit includes one control chip, the N voltage converting units share the control chip; when the control unit comprises a plurality of control chips, part of the N voltage conversion units share one control chip or each voltage conversion unit corresponds to one control chip.
According to an embodiment of the utility model, the N voltage conversion units have the same structure, and each voltage conversion unit includes a switch tube for voltage conversion, and part or all of the N voltage conversion units share the switch tube.
According to an embodiment of the present invention, each voltage conversion unit is a flyback conversion circuit, a forward conversion circuit, an LLC resonant circuit, a boost circuit, or a bridge circuit.
According to one embodiment of the present invention, a flyback converter circuit includes: one end of a primary winding of the transformer is connected with the main input end; the first end of the first switching tube is connected with the other end of the primary winding of the transformer, the second end of the first switching tube is grounded, and the control end of the first switching tube is connected with the control unit; the anode of the first diode is connected with one end of the secondary winding of the transformer; and the filter capacitor is connected between the output ends of the corresponding voltage conversion units in parallel, one end of the filter capacitor is connected with the cathode of the first diode, and the other end of the filter capacitor is connected with the other end of the secondary winding of the transformer.
According to an embodiment of the present invention, a first resistor is further connected in series between the second end of the first switching tube and the ground, and a connection point between the first resistor and the second end of the first switching tube is connected to the control unit.
According to one embodiment of the utility model, the N energy storage units have the same structure, and each energy storage unit comprises an energy storage capacitor, and the energy storage capacitors are connected in parallel between the output ends of the corresponding voltage conversion units.
According to an embodiment of the present invention, the current adjusting unit includes M current adjusting branches connected in parallel, where M is an integer greater than 1, and each current adjusting branch includes: one end of the current-limiting resistor is connected with one end of the N voltage transformation units which are connected in series; and one end of the current limiting switch is connected with the other end of the current limiting resistor, and the other end of the current limiting switch is connected with the main output end.
According to an embodiment of the present invention, the high voltage generating circuit for a catheter further comprises: and the input end of the voltage adjusting unit is connected with the output end of each voltage conversion unit, and the output end of the voltage adjusting unit is connected with the current adjusting unit and used for controlling the on-off between the output end of each voltage conversion unit and the current adjusting unit.
According to an embodiment of the present invention, a voltage adjusting unit includes: the N first switches correspond to the N voltage conversion units one by one, and each first switch is connected in series between the output end of the corresponding voltage conversion unit and the current adjusting unit.
According to one embodiment of the present invention, the N first switches are identical in structure and each of the first switches includes: one end of a switch of the relay is connected with the output end of the corresponding voltage conversion unit, and one end of a coil of the relay is connected with a preset power supply; the anode of the voltage-stabilizing tube is connected with the other end of the coil of the relay, and the cathode of the voltage-stabilizing tube is connected with one end of the coil of the relay; the anode of the second diode is connected with the other end of the switch of the relay, and the cathode of the second diode is connected with the current adjusting unit; and the first end of the second switch tube is connected with the other end of the coil of the relay, the second end of the second switch tube is grounded, and the control end of the second switch tube is connected with the control unit.
In order to achieve the above object, a second aspect of the present invention provides an ablation instrument, including a high voltage generation circuit for a catheter as in the first aspect.
According to the ablation tool provided by the embodiment of the utility model, the high-voltage generating circuit for the catheter can realize the rapid switching of different output powers, and the adopted components are small, so that the application prospect of the pulsed electric field ablation technology in arrhythmia treatment is improved.
Additional aspects and advantages of the utility model will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the utility model.
Drawings
FIG. 1 is a schematic diagram of a high voltage generation circuit for a catheter according to one embodiment of the present invention;
FIG. 2 is a schematic diagram of a high voltage generation circuit for a catheter according to another embodiment of the present invention;
FIG. 3 is a schematic diagram of a high voltage generation circuit for a catheter according to yet another embodiment of the present invention;
FIG. 4 is a schematic diagram of a high voltage generation circuit for a catheter according to yet another embodiment of the present invention;
FIG. 5 is a schematic diagram of a first switch of a high voltage transmit circuit for a conduit according to one embodiment of the present invention;
fig. 6 is a schematic structural view of an ablation instrument in accordance with an embodiment of the utility model.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the utility model and are not to be construed as limiting the utility model.
The high voltage generating circuit for a catheter and an ablation instrument according to embodiments of the present invention will be described with reference to the accompanying drawings.
Fig. 1 is a schematic structural diagram of a high voltage generating circuit for a catheter according to an embodiment of the present invention, and referring to fig. 1, the high voltage generating circuit may include: n voltage conversion units (N is an integer greater than 1), N energy storage units, a current adjustment unit 200, and a control unit 300.
The input ends of the N voltage conversion units are connected in parallel and then connected with the total input end of the high-voltage generating circuit, the output ends of the N voltage conversion units are connected in series and then connected with the total output end of the high-voltage generating circuit, the N energy storage units correspond to the N voltage conversion units one to one, each energy storage unit is connected between the output ends of the corresponding voltage conversion units, and each voltage conversion unit in the N voltage conversion units is used for performing voltage conversion on the input voltage of the total input end and charging the corresponding energy storage unit; the output ends of the N voltage conversion units are connected in series and then connected with the total output end through the current adjusting unit 200 to adjust the output current of the total output end; the control unit 300 is connected to the N voltage converting units and the current adjusting unit 200, and is used for controlling the N voltage converting units and the current adjusting unit 200 to adjust the output voltage and the output current of the total output terminal.
Specifically, the voltage conversion unit and the energy storage unit may include a plurality of units, and the specific number may be selected according to actual use requirements. As a specific example, referring to fig. 1, the high voltage generation circuit may include four voltage transformation units (voltage transformation units 111, 121, 131, and 141, respectively) and four energy storage units (energy storage units 112, 122, 132, and 142, respectively). First input ends of the voltage conversion units 111, 121, 131 and 141 are connected and then connected with a total input positive terminal Vin of the high-voltage generation circuit; second input ends of the voltage conversion units 111, 121, 131 and 141 are connected and then connected with a total input negative end GND of the high voltage generation circuit; a first output end of the voltage conversion unit 111 is connected with one end of the corresponding energy storage unit 112, and a second output end of the voltage conversion unit 111 is connected with the other end of the corresponding energy storage unit 112; a first output end of the voltage conversion unit 121 is connected to one end of the corresponding energy storage unit 122 and the other end of the energy storage unit 112, and a second output end of the voltage conversion unit 121 is connected to the other end of the corresponding energy storage unit 122; a first output end of the voltage conversion unit 131 is connected to one end of the corresponding energy storage unit 132 and the other end of the energy storage unit 122, and a second output end of the voltage conversion unit 131 is connected to the other end of the corresponding energy storage unit 132; a first output end of the voltage conversion unit 141 is connected to one end of the corresponding energy storage unit 142, the input end of the current adjustment unit 200, and the other end of the energy storage unit 132, and a second output end of the voltage conversion unit 141 is connected to the other end of the corresponding energy storage unit 142 and a negative total output end GND of the high voltage generation circuit; the output terminal of the current regulation unit 200 is connected to the total output positive terminal Vout of the high voltage generation circuit. The control unit 300 respectively performs voltage conversion on the input voltage of the total input terminal by controlling the voltage conversion units 111, 121, 131 and 141 to charge the corresponding energy storage units 112, 122, 132 and 142, and controls the current adjustment unit 200 to adjust the output voltage and the output current of the total output positive terminal Vout according to requirements.
When the high voltage generating circuit operates, the input terminals of the voltage converting units 111, 121, 131 and 141 are connected in parallel, and the same operating voltage can be obtained, but since the output terminals of the voltage converting units 111, 121, 131 and 141 are connected in series, the voltage at the output terminals of the voltage converting units 111, 121, 131 and 141 will increase step by step, that is, the voltage at one end of the energy storing units 112, 122, 132 and 142 increases step by step, that is, the voltage at A, B, C and the voltage at D point in fig. 1 increase sequentially, for example, the voltage at D point is the voltage of the energy storing unit 142, the voltage at C point is the sum of the voltages of the energy storing units 142 and 132, the voltage at B point is the sum of the voltages of the energy storing units 142, 132 and 122, and 112. The control unit 300 can control the plurality of voltage conversion units to realize fast switching of the output voltage of the total output end, for example, assuming that the maximum voltage corresponding to each energy storage unit is 500V, and the voltage range is 0-2000V, when the output voltage of 2000V needs to be obtained, four voltage conversion units can be controlled to work simultaneously, compared with only one voltage conversion unit, the obtaining speed of the output voltage is effectively improved, when the output voltage of 500V needs to be obtained, four energy storage units can be controlled to discharge simultaneously, compared with only one energy storage unit, the switching speed of the output voltage is greatly improved, and thus fast switching of the output voltage can be realized.
The control unit 300 may control the current adjusting unit 200, and change the output current of the total output end by changing the size of the resistor built in the current adjusting unit 200, for example, the current adjusting unit 200 may be a variable resistor with steplessly adjustable resistance, and the output current may be directly adjusted to the required current by changing the resistance value of the variable resistor, thereby implementing fast switching of different output currents.
Further, the control unit 300 may control the plurality of voltage converting units and the current adjusting unit 200 to realize fast switching of the output power of the total output terminal, for example, under the condition that the resistance value of the current adjusting unit 200 is not changed, fast switching of the output power may be realized by adjusting the plurality of voltage converting units; or, the output current is changed by adjusting the resistance of the current adjusting unit 200 while the voltage converting units are adjusted to meet the required voltage, so as to realize the fast switching of the output power. Therefore, the quick and flexible switching of the output power can be realized.
Therefore, the fast and flexible switching among different output voltages, output currents and output power can be realized through the plurality of voltage conversion units and the current adjusting unit, meanwhile, the output voltages are divided into N parts, which is equivalent to low-voltage control, so that each voltage conversion unit can be realized by adopting smaller components, and the application prospect of the pulsed electric field ablation technology on arrhythmia treatment is improved.
In some embodiments, the control unit 300 includes one or more control chips, wherein, when the control unit 300 includes one control chip, the N voltage converting units share the control chip; when the control unit 300 includes a plurality of control chips, a part of the N voltage conversion units shares one control chip or each voltage conversion unit corresponds to one control chip.
Specifically, the control chip in the control unit 300 may include one or more control chips, each control chip may control one voltage conversion unit, and may also control a plurality of voltage conversion units, and the specific number of the control chips and the number of the voltage conversion units controlled by each control chip may be selected according to actual use requirements. As a specific example, referring to fig. 2, the control unit 300 of the high voltage generating circuit includes two control chips, which are a control chip IC Controller-1 and a control chip IC Controller-2, respectively, each control chip controls two voltage converting units at the same time, and the same control chip has the same switching period, so that the voltage converting units under the control of the same control chip can output converted voltage more flexibly, and the staggered on-off of different control chips can be realized by controlling the on-off time of different control chips, thereby realizing the input of the minimum current ripple and the minimum voltage ripple, and further inputting the minimum capacitor.
In some embodiments, the N voltage converting units have the same structure, and each voltage converting unit includes a switching tube for performing voltage conversion, and some or all of the N voltage converting units share the switching tube.
That is to say, N voltage conversion units may share one or more switching tubes to perform voltage conversion through one or more switching tubes, and the specific number of switching tubes and the number of voltage conversion units controlled by each switching tube may be selected according to actual use requirements. As a specific example, with reference to fig. 2, the high voltage generating circuit includes two switching tubes, and each switching tube simultaneously controls two voltage converting units, and when the control unit 300 controls on/off of the switching tube, the voltage converting units corresponding to the switching tubes can be controlled to be turned on/off, so that cost and board layout size can be saved.
In some embodiments, each voltage conversion unit is a flyback conversion circuit, a forward conversion circuit, an LLC resonant circuit, a boost circuit, or a bridge circuit. That is to say, the voltage conversion unit in this application can be flyback conversion circuit, forward conversion circuit, LLC resonant circuit, exempt from circuit or bridge circuit etc. and guarantee that the type of voltage conversion unit is unanimous in the use, specifically adopt which kind of mode can select to set up according to actual demand.
In some embodiments, as shown in fig. 2, a flyback converter circuit includes: the circuit comprises a transformer (such as T1), a first switching tube (such as Q1), a first diode (such as D1) and a filter capacitor (such as C1), wherein one end of a primary winding of the transformer (such as T1) is connected with a total input positive terminal Vin; a first end of a first switch tube (for example, Q1) is connected to the other end of the primary winding of the transformer (for example, T1), a second end of the first switch tube (for example, Q1) is grounded GND, and a control end of the first switch tube (for example, Q1) is connected to the control unit 300; the anode of the first diode (e.g., D1) is connected to one end of the secondary winding of the transformer (e.g., T1); a filter capacitor (e.g., C1) is connected in parallel between the output terminals of the corresponding voltage conversion units, one end of the filter capacitor (e.g., C1) is connected to the cathode of the first diode (e.g., D1), and the other end of the filter capacitor (e.g., C1) is connected to the other end of the secondary winding of the transformer (e.g., T1).
Optionally, a first resistor (e.g., R1) is further connected in series between the second end of the first switch tube (e.g., Q1) and ground, and a connection point between the first resistor (e.g., R1) and the second end of the first switch tube (e.g., Q1) is connected to the control unit 300.
Optionally, the N energy storage units have the same structure, and each energy storage unit includes an energy storage capacitor, and the energy storage capacitors (e.g., C5) are connected in parallel between the output ends of the corresponding voltage conversion units.
The following description will be given taking as an example that each of the voltage conversion circuits shown in fig. 2 is a flyback conversion circuit. In fig. 2, the control unit 300 includes two control chips, each of which simultaneously controls two flyback converters, and each of the two flyback converters shares one switching tube.
Specifically, referring to fig. 2, the first flyback conversion circuit includes a transformer T1, a first switch Q1, a first diode D1 and a filter capacitor C1, the second flyback conversion circuit includes a transformer T2, a first switch Q2, a first diode D2 and a filter capacitor C2, the third flyback conversion circuit includes a transformer T3, a first switch Q3, a first diode D3 and a filter capacitor C3, and the fourth flyback conversion circuit includes a transformer T4, a first switch Q4, a first diode D4 and a filter capacitor C4. One end of primary windings of the transformers T1, T2, T3 and T4 is connected with a total input positive terminal Vin, a first end of a first switching tube Q1 is connected with the other ends of the primary windings of the transformers T1 and T2, and a first end of a first switching tube Q2 is connected with the other ends of the primary windings of the transformers T3 and T4; the second ends of the first switching tube Q1 and the first switching tube Q2 are grounded, the control end of the first switching tube Q1 is connected with the control chip IC Controller-1, and the control end of the first switching tube Q2 is connected with the control chip IC Controller-2; anodes of the first diodes D1, D2, D3 and D4 are connected to one end of the secondary windings of the transformers T1, T2, T3 and T4, respectively; filter capacitors C1, C2, C3 and C4 are connected in parallel between output terminals of the corresponding voltage converting units, one ends of the filter capacitors C1, C2, C3 and C4 are respectively connected to cathodes of the first diodes D1, D2, D3 and D4, the other ends of the filter capacitors C1, C2, C3 and C4 are respectively connected to the other ends of secondary windings of the transformers T1, T2, T3 and T4, and a secondary winding of the transformer T1 is grounded. A first resistor R1 is further connected in series between the second end of the first switch tube Q1 and the ground, a connection point between the first resistor R1 and the second end of the first switch tube Q1 is connected with the control chip IC Controller-1, a first resistor R2 is further connected in series between the second end of the first switch tube Q2 and the ground, and a connection point between the first resistor R2 and the second end of the first switch tube Q2 is connected with the control chip IC Controller-2. Each energy storage unit comprises an energy storage capacitor, and the energy storage capacitors C5, C6, C7 and C8 are respectively connected in parallel between the output ends of the corresponding flyback conversion circuits.
When the high-voltage generating circuit works, the primary windings of the transformers T1, T2, T3 and T4 obtain the same working voltage from the total input positive terminal Vin, when the control unit 300 controls the first switching tubes Q1 and Q2 to be conducted, the currents in the primary windings of the transformers T1, T2, T3 and T4 and the magnetic field in the magnetic core are increased, energy is stored in the magnetic core, because the voltages generated in the secondary windings of the transformers T1, T2, T3 and T4 are opposite, the first diodes D1, D2, D3 and D4 are in a reverse bias state and cannot be conducted, and at the moment, the voltages and currents are provided to the load by the energy storage capacitors C5, C6, C7 and C8; when the control unit 300 controls the first switching tubes Q1 and Q2 to be switched off, the current in the primary winding is 0, and at the same time, the magnetic field in the magnetic core begins to drop, a forward voltage is induced on the secondary winding, at this time, the first diodes D1, D2, D3 and D4 are in a forward bias state, the switched-on current flows into the energy storage capacitors C5, C6, C7, C8 and the load, and the energy stored in the magnetic core is transferred to the energy storage capacitors C5, C6, C7, C8 and the load. Since the secondary winding of the transformer T1 is grounded, the output voltage of the first flyback conversion circuit is an absolute voltage VO, and so on, the output voltage of the second flyback conversion circuit is 2VO, the output voltage of the third flyback conversion circuit is 3VO, and the output voltage of the fourth flyback conversion circuit is 4VO, thereby realizing the gradual increase of the output voltage. Further, the control unit 300 may implement fast switching of the output voltage by controlling the four voltage converting units, for example, controlling the four voltage converting units to work simultaneously to obtain an output voltage of, for example, 2000V, and then controlling the energy storing units corresponding to the four voltage converting units to discharge to obtain an output voltage of, for example, 500V, compared to a structure that one voltage converting unit and one energy storing unit are adopted, implement fast switching from 2000V to 500V.
In some embodiments, with continued reference to fig. 2, the current adjusting unit 200 includes M current adjusting branches connected in parallel, where M is an integer greater than 1, and each current adjusting branch includes: one end of the current-limiting resistor (such as R11) is connected with one end of the N voltage transformation units which are connected in series; and a current limiting switch (such as S11), wherein one end of the current limiting switch (such as S11) is connected with the other end of the current limiting resistor (such as R11), and the other end of the current limiting switch (such as S11) is connected with the positive end Vout of the total output.
Specifically, four current regulation branches are taken as an example for explanation, the first current regulation branch includes a current limiting resistor R11 and a current limiting switch S11, one end of the current limiting resistor R11 is connected to one end of the voltage conversion unit after being connected in series, one end of the current limiting switch S11 is connected to the other end of the current limiting resistor R11, and the other end of the current limiting switch S11 is connected to the positive total output terminal Vout; the second current adjusting branch circuit comprises a current-limiting resistor R22 and a current-limiting switch S22, one end of the current-limiting resistor R22 is connected with one end of the voltage conversion unit after being connected in series, one end of the current-limiting switch S22 is connected with the other end of the current-limiting resistor R22, and the other end of the current-limiting switch S22 is connected with the positive end Vout of the total output; the third current adjusting branch comprises a current-limiting resistor R33 and a current-limiting switch S33, one end of the current-limiting resistor R33 is connected with one end of the voltage conversion unit after being connected in series, one end of the current-limiting switch S33 is connected with the other end of the current-limiting resistor R33, and the other end of the current-limiting switch S33 is connected with the positive end Vout of the total output; the fourth current adjusting branch comprises a current-limiting resistor R44 and a current-limiting switch S44, one end of the current-limiting resistor R44 is connected with one end of the voltage conversion unit after being connected in series, one end of the current-limiting switch S44 is connected with the other end of the current-limiting resistor R44, and the other end of the current-limiting switch S44 is connected with the positive end Vout of the total output. It should be noted that the resistances of the current limiting resistors R11, R22, R33, and R44 may be the same or different.
When the high-voltage generating circuit works, as shown in fig. 2, the first to fourth current adjusting branches are connected in parallel, the voltage obtained by each current adjusting branch is HV _ OUT, and the on-off states of different current adjusting branches are controlled by controlling the on-off of the current limiting switches in the current adjusting branches, so as to adjust the output current of the total output positive terminal Vout according to the current limiting resistors of the turned-on current adjusting branches. For example, when the voltage HV _ OUT input to the current adjusting unit 200 is unchanged, the current limiting switch S11 is closed, the remaining current limiting switches are opened, the output current is the ratio of the input voltage HV _ OUT to the current limiting resistor R11, the current limiting switches S11 and S22 are closed, the remaining current limiting switches are opened, and the output current is the ratio of the input voltage HV _ OUT to the current limiting resistors R11 and R22 connected in parallel, so that the output current can be switched quickly, that is, the current limiting resistors with different resistance values are selected, or the current limiting resistors with different numbers are selected to adjust the output current of the total output positive terminal Vout.
In some embodiments, as shown in fig. 3, the high voltage generation circuit further comprises: and an input end of the voltage adjusting unit 400 is connected with an output end of each voltage conversion unit, and an output end of the voltage adjusting unit 400 is connected with the current adjusting unit 200, so as to control the on/off between the output end of each voltage conversion unit and the current adjusting unit 400.
Specifically, a first input end of the voltage adjusting unit 400 is connected to the first output end of the voltage converting unit 111 and one end of the corresponding energy storing unit 112, a second input end of the voltage adjusting unit 400 is connected to the first output end of the voltage converting unit 121, the other end of the energy storing unit 112 and one end of the energy storing unit 122, a third input end of the voltage adjusting unit 400 is connected to the first output end of the voltage converting unit 131, the other end of the energy storing unit 122 and one end of the energy storing unit 132, and a fourth input end of the voltage adjusting unit 400 is connected to the first output end of the voltage converting unit 141, the other end of the energy storing unit 132 and one end of the energy storing unit 142; the output end of the voltage adjusting unit 400 is connected to the current adjusting unit 200 to control the on/off of the first output ends of the voltage transforming units 111, 121, 131 and 141 and the current adjusting unit 200 according to the requirement.
When the high voltage generating circuit operates, as shown in fig. 3, the voltage adjusting unit 400 may control on/off between the first output terminals of the voltage converting units 111, 121, 131, and 141 and the current adjusting unit 200 to further achieve fast switching output of multiple voltages. For example, when the voltage adjustment unit 400 controls the voltage transformation unit 141 to communicate with the current adjustment unit 200, the input terminal of the current adjustment unit 200 can directly obtain the same voltage as the point D; when the voltage adjusting unit 400 controls the voltage transforming unit 131 to communicate with the current adjusting unit 200, the input end of the current adjusting unit 200 can directly obtain the same voltage as the point C; when the voltage adjusting unit 400 controls the voltage transforming unit 121 to communicate with the current adjusting unit 200, the input end of the current adjusting unit 200 can directly obtain the same voltage as the point B; when the voltage adjusting unit 400 controls the voltage transforming unit 111 to communicate with the current adjusting unit 200, the input end of the current adjusting unit 200 can directly obtain the same voltage as the point a, so that different output voltages can be obtained quickly; meanwhile, the output range of the voltage can be extended, for example, when the maximum voltage corresponding to each voltage conversion unit is 500V, the voltage range can be 0-2000V.
Compared with the existing voltage conversion unit, when the voltage is switched, for example, from 2000V to 500V, the scheme of only one voltage conversion unit needs to discharge from 2000V to 500V to complete the voltage switching, the discharge time is long, and the switching speed is slow, but the voltage regulation unit 200 can directly control the first output end of the voltage conversion unit 141 to be communicated with the total output end Vout, and the others are in the off state, so that the voltage switching of 500V can be completed quickly. Meanwhile, a wide voltage range of 0-2000V can be achieved, only one voltage conversion unit is provided, or the voltage range of 0-2000V cannot be achieved, or even if the voltage conversion unit can be achieved, the voltage conversion unit can be achieved only by a high-power device, and the voltage conversion unit can achieve wide-range voltage output and can be achieved by small-sized components.
Therefore, the voltage conversion units with the input connected in parallel and the output connected in series can realize multi-voltage rapid switching output, widen the output range of the voltage and improve the application prospect of the pulsed electric field ablation technology in arrhythmia treatment.
In some embodiments, as shown in fig. 4, the voltage adjusting unit 400 includes: the N first switches correspond to the N voltage conversion units one to one, and each first switch is connected in series between the output end of the corresponding voltage conversion unit and the current adjustment unit 200.
Specifically, the voltage adjusting unit 400 may include four first switches S1, S2, S3, and S4, respectively, and the first switches S1, S2, S3, and S4, respectively, are connected in series between the output terminal of the corresponding voltage transforming unit and the current adjusting unit 200. The voltage output of the corresponding voltage conversion unit is realized by controlling the on and off of the first switches S1, S2, S3 and S4, and then the fast switching of the output voltage is realized, for example, the first switch S1 is closed, the rest of the first switches are open, the output voltage is VO, and if the first switch S4 is closed and the rest of the first switches are open, the output voltage is 4VO, so that the fast switching of the output voltage from VO to 4VO is realized, and the output voltage range is expanded.
Further, as shown in fig. 5, the N first switches have the same structure, and each first switch includes: the voltage regulator comprises a relay (such as K1), a voltage regulator tube (such as D5), a second diode (such as D9) and a second switch tube (such as Q3), wherein one end of a switch of the relay (such as K1) is connected with the output end of a corresponding voltage conversion unit, and one end of a coil of the relay (such as K1) is connected with a preset power supply V1; the anode of a voltage regulator tube (such as D5) is connected with the other end of the coil of the relay (such as K1), and the cathode of the voltage regulator tube (such as D5) is connected with one end of the coil of the relay (such as K1); an anode of the second diode (e.g., D9) is connected to the other end of the switch of the relay (e.g., K1), and a cathode of the second diode (e.g., D9) is connected to the current adjusting unit 200; a first terminal of a second switching tube (e.g., Q3) is connected to the other terminal of the coil of the relay (e.g., K1), a second terminal of the second switching tube (e.g., Q3) is grounded, and a control terminal of the second switching tube (e.g., Q3) is connected to the control unit 300.
Specifically, the following description will be given taking four first switches corresponding to four voltage conversion units as an example, and as shown in fig. 5, the first switch S1 includes a relay K1, a voltage regulator D5, a second diode D9, and a second switch Q3, the first switch S2 includes a relay K2, a voltage regulator D6, a second diode D10, and a second switch Q4, the first switch S3 includes a relay K3, a voltage regulator D7, a second diode D11, and a second switch Q5, and the first switch S4 includes a relay K4, a voltage regulator D8, a second diode D12, and a second switch Q6. One end of the switch of the relays K1, K2, K3 and K4 is connected with the output end of the corresponding voltage conversion unit respectively; one ends of coils of the relays K1, K2, K3 and K4 are connected with a preset power supply V1, anodes of voltage-stabilizing tubes D5, D6, D7 and D8 are connected with the other ends of the coils of the relays K1, K2, K3 and K4 respectively, and cathodes of the voltage-stabilizing tubes D5, D6, D7 and D8 are connected with one ends of the coils of the relays K1, K2, K3 and K4 respectively; anodes of the second diodes D9, D10, D11, and D12 are connected to the other ends of the switches of the relays K1, K2, K3, and K4, respectively, and cathodes of the second diodes D9, D10, D11, and D12 are connected to the current adjustment unit 200; first ends of the second switching tubes Q3, Q4, Q5 and Q6 are connected to the other ends of the coils of the relays K1, K2, K3 and K4, respectively, second ends of the second switching tubes Q3, Q4, Q5 and Q6 are all grounded, and control ends of the second switching tubes Q3, Q4, Q5 and Q6 are connected to the control unit 300, respectively.
When the high-voltage generating circuit works, the final output voltage of the total output positive terminal Vout can be controlled by controlling the on/off of the relays K1, K2, K3 and K4, for example, when the control unit 300 controls the second switching tube Q3 to be turned on and controls the other second switching tubes to be turned off, that is, the relay K1 is controlled to be turned on, and when the other relays are turned off, the output voltage of the total output positive terminal Vout is VO; when the control unit 300 controls the second switch tube Q4 to be turned on and controls the other second switch tubes to be turned off, that is, the relay K2 is controlled to be closed, and when the other relays are turned off, the output voltage of the total output positive terminal Vout is 2VO, and so on, thereby realizing the gradual increase and the rapid switching of the output voltage.
The second switching tubes Q3, Q4, Q5 and Q6 have a function of preventing voltage backflow generated by the mistaken opening of the upper-level relay, and even if the relays K1, K2, K3 and K4 are all opened, the high voltage 4VO correspondingly output by the relay K1 cannot flow back to other low voltage circuits to cause element burnout; and if the latter stage does not work, for example, relative to the relay K2, the relay K1 does not work, the relay K1 is equivalent to no load, and the rear end of the relay K1 is equivalent to suspension, so that the problem of voltage difference is avoided, that is, the relay with low voltage can be continuously used.
In summary, according to the high voltage generating circuit for a catheter of the embodiment of the present invention, the input ends of the voltage transforming units are connected in parallel and then connected to the total input end of the high voltage generating circuit, the output ends of the voltage transforming units are connected in series and then connected to the total output end of the high voltage generating circuit, the voltage adjusting unit is connected between the output end and the total output end of each voltage transforming unit for controlling the on/off between the output end and the total output end of each voltage transforming unit, and the control unit is connected to each voltage transforming unit and the voltage adjusting unit for controlling the voltage transforming units and the voltage adjusting unit to adjust the output voltage of the total output end. Therefore, the rapid switching of different output currents can be realized through the plurality of voltage conversion units and the current adjusting unit, and the application prospect of the pulsed electric field ablation technology on arrhythmia treatment is improved.
Fig. 6 is a schematic structural diagram of an ablation instrument according to an embodiment of the present invention, and referring to fig. 6, the ablation instrument 1000 includes the high voltage generation circuit 100 for a catheter described above.
According to the ablation tool provided by the embodiment of the utility model, through the high-voltage generating circuit for the catheter, the rapid switching of different output currents can be realized through the plurality of voltage conversion units and the current adjusting unit, and the application prospect of the pulsed electric field ablation technology on arrhythmia treatment is improved.
It should be noted that the logic and/or steps represented in the flowcharts or otherwise described herein, such as an ordered listing of executable instructions that can be considered to implement logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, processor-containing system, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium could even be paper or another suitable medium upon which the program is printed, as the program can be electronically captured, via for instance optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner if necessary, and then stored in a computer memory.
It should be understood that portions of the present invention may be implemented in hardware, software, firmware, or a combination thereof. In the above embodiments, the various steps or methods may be implemented in software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, any one or combination of the following techniques, which are known in the art, may be used: a discrete logic circuit having a logic gate circuit for implementing a logic function on a data signal, an application specific integrated circuit having an appropriate combinational logic gate circuit, a Programmable Gate Array (PGA), a Field Programmable Gate Array (FPGA), or the like.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.
Claims (12)
1. A high voltage generating circuit for a catheter, comprising:
the input ends of the N voltage conversion units are connected with the total input end of the high-voltage generating circuit after being connected in parallel, the output ends of the N voltage conversion units are connected with the total output end of the high-voltage generating circuit after being connected in series, the N energy storage units correspond to the N voltage conversion units one to one, each energy storage unit is connected between the output ends of the corresponding voltage conversion units, each voltage conversion unit in the N voltage conversion units is used for performing voltage conversion on the input voltage of the total input end and charging the corresponding energy storage unit, and N is an integer greater than 1;
the output ends of the N voltage conversion units are connected in series and then are connected with the total output end through the current adjustment unit, so that the output current of the total output end can be adjusted;
and the control unit is connected with the N voltage conversion units and the current adjusting unit and is used for controlling the N voltage conversion units and the current adjusting unit so as to adjust the output voltage and the output current of the total output end.
2. The high voltage generating circuit for a catheter according to claim 1, wherein the control unit comprises one or more control chips, wherein when the control unit comprises one control chip, the N voltage converting units share the control chip; when the control unit comprises a plurality of control chips, part of the N voltage conversion units share one control chip or each voltage conversion unit corresponds to one control chip.
3. The high voltage generating circuit for a conduit according to claim 1, wherein the N voltage converting units have the same structure and each voltage converting unit comprises a switch tube for voltage conversion, and part or all of the N voltage converting units share the switch tube.
4. The high voltage generating circuit for a conduit of claim 3, wherein each voltage conversion unit is a flyback conversion circuit, a forward conversion circuit, an LLC resonant circuit, a boost circuit, or a bridge circuit.
5. The high voltage generating circuit for a conduit of claim 4, wherein the flyback converter circuit comprises:
one end of a primary winding of the transformer is connected with the main input end;
a first end of the first switching tube is connected with the other end of the primary winding of the transformer, a second end of the first switching tube is grounded, and a control end of the first switching tube is connected with the control unit;
the anode of the first diode is connected with one end of the secondary winding of the transformer;
and the filter capacitors are connected between the output ends of the corresponding voltage conversion units in parallel, one ends of the filter capacitors are connected with the cathodes of the first diodes, and the other ends of the filter capacitors are connected with the other ends of the secondary windings of the transformers.
6. The high voltage generating circuit for the conduit of claim 5, wherein a first resistor is further connected in series between the second end of the first switch tube and the ground, and a connection point between the first resistor and the second end of the first switch tube is connected with the control unit.
7. The high voltage generating circuit for a conduit according to claim 1, wherein the N energy storage units have the same structure and each energy storage unit comprises an energy storage capacitor connected in parallel between the output terminals of the corresponding voltage converting units.
8. The high voltage generating circuit for a catheter according to claim 1, wherein the current regulating unit comprises M current regulating branches connected in parallel, where M is an integer greater than 1, and each current regulating branch comprises:
one end of the current-limiting resistor is connected with one end of the N voltage transformation units which are connected in series;
and one end of the current limiting switch is connected with the other end of the current limiting resistor, and the other end of the current limiting switch is connected with the main output end.
9. The high voltage generating circuit for a catheter according to any one of claims 1-8, further comprising: and the input end of the voltage adjusting unit is connected with the output end of each voltage conversion unit, and the output end of the voltage adjusting unit is connected with the current adjusting unit and used for controlling the on-off between the output end of each voltage conversion unit and the current adjusting unit.
10. The high voltage generating circuit for a catheter according to claim 9, wherein the voltage adjusting unit comprises: the N first switches are in one-to-one correspondence with the N voltage conversion units, and each first switch is connected in series between the output end of the corresponding voltage conversion unit and the current adjustment unit.
11. The high voltage generating circuit for a conduit of claim 10, wherein the N first switches are identical in structure and each first switch comprises:
one end of a switch of the relay is connected with the output end of the corresponding voltage conversion unit, and one end of a coil of the relay is connected with a preset power supply;
the anode of the voltage-stabilizing tube is connected with the other end of the coil of the relay, and the cathode of the voltage-stabilizing tube is connected with one end of the coil of the relay;
the anode of the second diode is connected with the other end of the switch of the relay, and the cathode of the second diode is connected with the current adjusting unit;
and the first end of the second switch tube is connected with the other end of the coil of the relay, the second end of the second switch tube is grounded, and the control end of the second switch tube is connected with the control unit.
12. An ablation instrument comprising a catheter and a high voltage generation circuit for a catheter according to any one of claims 1 to 11.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023016482A1 (en) * | 2021-08-10 | 2023-02-16 | 苏州艾科脉医疗技术有限公司 | High-voltage generating circuit for catheter and ablation tool |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023016482A1 (en) * | 2021-08-10 | 2023-02-16 | 苏州艾科脉医疗技术有限公司 | High-voltage generating circuit for catheter and ablation tool |
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