CN215866716U

CN215866716U - Troponin I's chromatography test paper is with card shell, detection card

Info

Publication number: CN215866716U
Application number: CN202121199014.2U
Authority: CN
Inventors: 林佳慧; 倪燕婕; 周丹丹
Original assignee: Suzhou Guoke Junhao Biotechnology Co ltd
Current assignee: Suzhou Guoke Junhao Biotechnology Co ltd
Priority date: 2021-05-31
Filing date: 2021-05-31
Publication date: 2022-02-18
Anticipated expiration: 2031-05-31

Abstract

The utility model provides a card shell for troponin I chromatography test paper, which comprises a shell body and a test paper cover, wherein the shell body comprises: the cavity is used for clamping a test strip for detecting troponin I by chromatography; the sample adding hole corresponds to the position of the sample adding pad of the test strip; loading the sample loading pad through the sample loading hole; an observation window; the protective shell covers the sampling hole and is used for preventing air from entering the sampling hole; during detection, the protective shell is uncovered, and the sample adding hole is exposed for sample adding. The utility model also provides a detection card. Through openly setting up the protective housing at the application of sample hole, be in the storage state when the detection card body, the certain air of protective housing separation contacts the application of sample pad through the application of sample hole to prevent that the application of sample pad from absorbing moisture and taking place the migration and influence the accuracy of the testing result of test paper strip. When the detection card body is in a use state, the protective shell is uncovered, and the sample adding hole is exposed, so that the sample can be added. The use is simple and convenient, the placing time for removing the outer packaging bag of the detection card body can be prolonged, and the cost waste is reduced.

Description

Troponin I's chromatography test paper is with card shell, detection card

Technical Field

The utility model relates to the technical field of immunodetection, in particular to a shell and a detection card for troponin I chromatography test paper.

Background

Cardiac troponin I (cTnI) is one of three subunits (cTnI, cTnC and cTnT) of cardiac troponin (cTn), is a specific antigen of the heart, is released into blood circulation to be a sensitive and highly specific marker of myocardial cell injury, and has important significance for diagnosis, prognosis, curative effect judgment and the like of certain cardiovascular diseases. Compared with other indexes, the cTnI appears early in blood, has long duration and is specific to myocardial cells, so that the diagnosis sensitivity and the specificity for AMI are high, and the cTnI can be used for evaluating myocardial protection and myocardial damage of cardiac surgery and postoperative monitoring, prognosis and curative effect judgment of AMI and cardiac surgery. The cardiac troponin I has wide application prospect in clinic.

The immunochromatography detection card is used as one of troponin I detection means, and has the characteristics of simple and convenient operation, quick reaction, suitability for field detection, economy and practicability. When in use, the sample is dropped into the sample hole of the detection card. When the detection card is stored, the detection card is sealed and packaged by an aluminum foil bag, and the packaging bag needs to be used as soon as possible after being torn off so as to avoid the influence of the environmental humidity on the accuracy of a detection result.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects of the prior art, the utility model provides the card shell for the troponin I chromatography test paper, which is used for clamping the test paper strip and can prolong the storage time of the detection card body in the air after the plastic packaging bag is removed.

In order to achieve the above object, the present invention is achieved by the following technical solutions.

The utility model provides a card shell for troponin I chromatography test paper, which comprises a shell, wherein the shell comprises:

the cavity is used for clamping a test strip for detecting troponin I by chromatography;

the sample adding hole corresponds to the position of the sample adding pad of the test strip; loading the sample loading pad through the sample loading hole;

the observation window is of a transparent structure; the observation window corresponds to the structure display area of the test strip;

the protective shell covers the sampling hole and is used for preventing air from entering the sampling hole;

during detection, the protective shell is uncovered, and the sample adding hole is exposed for sample adding.

Preferably, the protective shell is adsorbed to the upper surface of the housing.

Preferably, the protective shell is an opaque structure; the inner walls of the two sides of the containing cavity are provided with sliding grooves, and one end of the shell is provided with a notch communicated with the sliding grooves; one end of the protective shell penetrates through the notch and then is connected to the sliding groove in a sliding mode; when the detection card body is used, the protective shell is accommodated in the containing cavity and covers the sample adding pad.

Preferably, the protective shell is a plate-shaped structure with adsorbability on one surface.

Preferably, the protective shell is provided with a limiting block, and the side wall of the accommodating cavity is provided with a stop block; the limiting block is matched with the stop block to limit one end of the protective shell to be separated from the sliding groove.

Preferably, when the protective shell is received in the cavity, the protective shell covers the result display area of the test strip.

Preferably, the housing comprises an upper housing and a lower housing; the upper shell and the lower shell are clamped together to form the containing cavity.

Preferably, the sliding groove is provided on the upper case.

Preferably, the protective shell is provided with a fool-proof mark; when the protective shell is received in the containing cavity, the fool-proof mark indicates that the detection card body is waste through the window of the shell.

A second object of the present invention is to provide a test card, comprising:

a test strip for detecting troponin I;

a cartridge for chromatographic test strips of troponin I as described above; the test strip is arranged in the cavity; the sample adding pad of the test strip corresponds to the sample adding hole in position.

Compared with the prior art, the utility model has the beneficial effects that:

the utility model provides a troponin I chromatography test paper card shell, wherein a protective shell is arranged on the front surface of a sample adding hole, and when a detection card body is in a storage state, the protective shell prevents certain air from contacting a sample adding pad through the sample adding hole, so that the accuracy of a detection result of a test paper strip is prevented from being influenced by moisture absorption and migration of the sample adding pad. When the detection card body is in a use state, the protective shell is uncovered, and the sample adding hole is exposed, so that the sample can be added. The use is simple and convenient, the placing time for removing the outer packaging bag of the detection card body can be prolonged, and the cost waste is reduced.

In a preferred scheme, after the detection card body finishes using, the protective housing is received in the appearance intracavity of casing and is sheltered from the application of sample pad, and remaining sample composition that awaits measuring gets into the outside air in the application of sample pad of certain degree separation, when reducing because of the detected object has the propagated disease, uses the in-process that detects the detection card body to the pollution of environment.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood and to be implemented according to the content of the description, the following detailed description is given with reference to the preferred embodiments of the present invention and the accompanying drawings. The detailed description of the present invention is given in detail by the following examples and the accompanying drawings.

Drawings

The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the utility model and together with the description serve to explain the utility model without limiting the utility model. In the drawings:

fig. 1 is a schematic perspective view of a housing according to an embodiment of the present invention;

FIG. 2 is a cross-sectional view of a housing in accordance with an embodiment of the present invention;

FIG. 3 is a schematic diagram of an exploded structure of the housing according to an embodiment of the present invention;

FIG. 4 is a schematic perspective view of an embodiment of the present invention when the protective case is not assembled to the upper case;

FIG. 5 is a schematic perspective view of an upper case assembled with a protective case according to an embodiment of the present invention;

FIG. 6 is a schematic perspective view of a test strip according to an embodiment of the present invention;

fig. 7 is a schematic diagram of an exploded structure of the detection card body according to an embodiment of the utility model.

In the figure:

1. detecting a card body;

10. a housing; 101. an upper housing; 102. a lower housing; 11. a cavity; 111. a chute; 112. a stopper; 12. a sample application hole; 13. a protective shell; 131. a limiting block; 14. a notch; 15. an observation window;

20. a test strip; 21. a sample addition pad; 22. a bonding pad; 23. a nitrocellulose pad; 231. detecting lines; 232. a quality control line; 24. a water absorbent pad; 25. PVC sheet.

Detailed Description

The foregoing and other objects, features, aspects and advantages of the present invention will become more apparent from the following detailed description of the present invention when taken in conjunction with the accompanying drawings, which will enable those skilled in the art to practice the present invention with reference to the accompanying specification. In the drawings, the shape and size may be exaggerated for clarity, and the same reference numerals will be used throughout the drawings to designate the same or similar components. In the following description, terms such as center, thickness, height, length, front, back, rear, left, right, top, bottom, upper, lower, and the like are used based on the orientation or positional relationship shown in the drawings. In particular, "height" corresponds to the dimension from top to bottom, "width" corresponds to the dimension from left to right, and "depth" corresponds to the dimension from front to back. These relative terms are for convenience of description and are not generally intended to require a particular orientation. Terms concerning attachments, coupling and the like (e.g., "connected" and "attached") refer to a relationship wherein structures are secured or attached, either directly or indirectly, to one another through intervening structures, as well as both movable or rigid attachments or relationships, unless expressly described otherwise.

The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict.

Example 1

The present invention provides a card shell for a chromatography test paper for troponin I, as shown in fig. 1 to 7, comprising a housing 10, the housing 10 comprising:

the cavity 11 is used for clamping a test strip 20 for detecting troponin I by chromatography;

the sample adding hole 12 corresponds to the position of the sample adding pad 21 of the test strip 20; applying a sample to the sample addition member 21 of the test strip 20 through the sample addition hole 12;

the observation window 15 is of a transparent structure; the observation window 15 corresponds to the structure display area of the test strip 20;

a protective shell 13 covering the sampling hole 12 for blocking air from entering the sampling hole 12;

during detection, the protective shell 13 is uncovered, and the sample adding hole 12 is exposed for sample adding. Specifically, the casing 10 is used for holding a test strip 20 to form a test card body 1 for detecting troponin I. Need keep dry when test paper strip 20 stores, openly set up protective housing 13 through adding sample hole 12, be in the storage state when detecting card body 1, protective housing 13 separation certain air passes through adding sample hole 12 and contacts application of sample pad 21 to prevent that application of sample pad 21 from absorbing moisture and taking place the migration and influence test paper strip 20's testing result's accuracy. When the detection card body 1 is in a use state, the protective shell 13 is uncovered, and the sample adding hole 12 is exposed, so that the sample can be added. The use is simple and convenient, the placing time for removing the outer packaging bag of the detection card body 1 can be prolonged, and the cost waste is reduced. In one embodiment, the observation window 15 is a glass window corresponding to the position of the test result display area of the test strip 20, so as to display the test result of the test strip 26 to the user.

In one embodiment, the protective shell 13 is attached to the upper surface of the housing 10. The protective shell 13 may be an adsorption film or adsorption paper, and is adsorbed on the housing 10, so that the protective shell 13 is easily installed or removed. Further, the case 10 is usually a plastic case, and in order to increase the adsorbability between the protective case 13 and the upper surface of the case 10, an adsorption layer (not shown) is provided at a position where the wells 12 are provided in the case 10, and the adsorption layer adsorbs the sample 13.

In one embodiment, the protective casing 13 is an opaque structure; sliding grooves 111 are formed in the inner walls of the two sides of the accommodating cavity 11, and a notch 14 communicated with the sliding grooves 111 is formed in one end of the shell 10; one end of the protective shell 13 passes through the notch 14 and then is slidably connected to the sliding groove 111; after the detection card body 1 is used, the protective shell 13 is received in the accommodating cavity 11 and covers the sample addition member 21. When the detection card body 1 needs to be used, the protective shell 13 is uncovered to expose the sample adding hole 12 for sample adding; when the detection card body 1 is used and needs to be discarded, the uncovered protective shell 13 is pushed into the accommodating cavity 11 through the sliding fit of the protective shell and the sliding groove 111, the protective shell 13 is designed to be long, the protective shell 13 can cover the sample adding pad 21 after entering the accommodating cavity 11, the sample adding pad 21 is prevented from contacting with the outside air through the sample adding hole 12, the probability that the sample in the sample adding pad 21 enters the outside air is reduced, when a detection object has a propagated disease, the probability of air disease propagation caused by the used detection card sample 1 is reduced, and the environmental protection performance of the detection card sample 1 after use is improved.

Furthermore, because one end of the protective shell 13 needs to penetrate through the notch 14 and then extend into the cavity 11, and the shell 10 is used for ensuring the dryness of the environment where the test strip 20 is located, the notch 14 is not too large, and the protective shell 13 needs to have certain stiffness so as to be convenient for sliding in the sliding groove 111, and the thickness of the protective shell 13 is 0.3-0.5 mm.

Further, the protective case 13 has a plate-like structure having adsorbability on one surface. The protective shell 13 is free from absorption, so as to increase the firmness of the absorption connection with the shell 10. The protective shell 13 is a plate-shaped structure to increase stiffness thereof, so that the protective shell 13 slides in the sliding slot 111.

In an embodiment, the protective shell 13 is provided with a limiting block 131, and a stop block 112 is arranged on the side wall of the cavity 11; the stop block 131 cooperates with the stop block 112 to limit one end of the protective shell 13 from separating from the sliding slot 111. Because the overall size of the detection card body 1 is miniaturized, the inner space of the shell 10 is small, and one end of the protective shell 13 in the accommodating cavity 11 is locked by the limit block 131 and the stop block 112 which are simple and small in design structure, so that the end part of the protective shell 13 is kept in sliding connection with the sliding groove 111.

In one embodiment, when the protective shell 13 is received in the cavity 11, the protective shell 13 covers the result display area of the test strip 20. Through the length of design protective housing 13 for protective housing 13 slides into and holds the intracavity 11 back, and protective housing 13 can cover the result display area of test paper strip 20, with protection user's privacy, improves user's use and experiences the sense.

In one embodiment, the housing 10 includes an upper housing 101, a lower housing 102; the upper shell 101 and the lower shell 102 jointly clamp and form the cavity 11, so that the test strip 20 can be mounted. In addition, the sliding groove 111 is arranged on the upper shell 101 or the lower shell 102, and the arrangement of the sliding groove 111 only needs to change the processing mold of the upper shell 101 or the lower shell 102, so that the overall processing cost of the shell 10 is reduced. Further, the upper housing 101 and the lower housing 102 are connected by means including, but not limited to, snap, and fastener connection to facilitate quick assembly.

Further, the sliding groove 111 is disposed on the upper case 101. The sample application hole 12 is provided in the upper case 101, and the chute 111 is provided in the upper case 101 to facilitate assembly of the protective case 13. When the housing 10 is assembled, the protective housing 13 is assembled on the upper housing 101, and then the test strip 20 is clamped in the upper housing 101 and the lower housing 102, so that the assembly is simple.

In one embodiment, the protective shell 13 is provided with a fool-proof mark (not shown); when the protective shell 13 is received in the accommodating cavity 11, the fool-proof mark indicates that the detection card body 1 is waste through the window of the shell 10. Because the protective housing 13 is opaque structure, has a plurality of detection objects when the user detects, does not abandon in time after having the detection card body 1 to use, and when the protective housing 13 blocks application of sample hole 12 and/or observation window 15, strengthens distinguishing detection card body 1 user state through preventing slow-witted sign. Further, the fool-proof mark may be a text, such as a "discarded" or "used" text mark; or a pattern, such as a pattern mark of "X", for indicating that the detection card body 1 is used and is waste, and reminding the user to dispose the waste in time.

In one embodiment, the protective shell 13 is provided with a handle for lifting the protective shell 13 so as to facilitate the user to uncover the protective shell 13.

Example 2

A test card comprising a test card body 1, as shown in fig. 1 to 7, the test card body 1 comprising:

a test strip 20 for detecting troponin I;

a cartridge for chromatographic test strips of troponin I as described above; the test strip 20 is arranged in the cavity 11; the sample adding pad 21 of the test strip 20 corresponds to the sample adding hole 12.

Specifically, the test strip 20 comprises a sample addition pad 21, a combination pad 22, a nitrocellulose membrane 23, a water absorption pad 24, and a PVC plate 25, wherein the PVC plate 25 is used for bearing the sample addition pad 21, the combination pad 22, the nitrocellulose membrane 23, and the water absorption pad 24; one end of the sample addition pad 21 is laid on the combination pad 22, and the combination pad 22 and the water absorption pad 24 are respectively laid on both ends of the nitrocellulose membrane 23. The combination pad 22 is internally provided with a colloidal gold labeled troponin I antibody and a colloidal gold labeled mouse IgG, the nitrocellulose membrane 23 is internally provided with a detection line 231 and a quality control line 232, the detection line 231 is internally provided with an anti-troponin I antibody, and the quality control line 232 is internally provided with a goat anti-mouse IgG polyclonal antibody. The absorbent pad 24 is used to absorb the substances migrated out of the nitrocellulose membrane 23.

When the detection card body 1 is used for detection, a sample to be detected is dripped on the sample adding pad 21 from the sample adding hole 12 of the shell 10, the sample to be detected is migrated to the combination pad 22 on the sample adding pad 21, and when the sample to be detected contains troponin I, the troponin I in the sample to be detected is combined with the anti-troponin I antibody marked by the colloidal gold on the combination pad 22 to generate a troponin I-colloidal gold-marked anti-troponin I antibody compound; the complex and the mouse IgG labeled by the colloidal gold in the binding pad are migrated to the nitrocellulose membrane 23 and moved to the detection line 231, the complex reacts with the anti-troponin I antibody in the detection line 231 to generate a larger complex, and the detection line 231 shows a corresponding color and a color band showing positive. The colloidal gold-labeled mouse IgG moves to the quality control line 232, and binds to the goat anti-mouse IgG polyclonal antibody in the quality control line 232, thereby showing a color. The quality control line 232 has color bands, and the detection result is effective; the quality control line 232 has no color band, the detection result is invalid, and the detection card body 1 needs to be replaced for retesting.

Through casing 10 structural design, after the plastic packaging bag is demolishd to detection card body 1, protective housing 13 covers application of sample hole 12, can prolong the save time that detection card body 1 arranged in the air.

The foregoing is merely a preferred embodiment of the utility model and is not intended to limit the utility model in any manner; those skilled in the art can readily practice the utility model as shown and described in the drawings and detailed description herein; however, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the scope of the utility model as defined by the appended claims; meanwhile, any changes, modifications, and evolutions of the equivalent changes of the above embodiments according to the actual techniques of the present invention are still within the protection scope of the technical solution of the present invention.

Claims

1. Card shell for chromatographic test paper of troponin I, including casing (10), characterized in that, casing (10) includes:

the device comprises a cavity (11) for clamping a test strip (20) for detecting troponin I by chromatography;

the sample adding hole (12), the sample adding hole (12) corresponds to the position of a sample adding pad (21) of the test strip (20); applying a sample to the sample application pad (21) through the sample application hole (12);

the observation window (15) is of a transparent structure; the observation window (15) corresponds to the structure display area of the test strip (20);

the protective shell (13) covers the sampling hole (12) and is used for preventing air from entering the sampling hole (12);

during detection, the protective shell (13) is uncovered, and the sample adding hole (12) is exposed for sample adding.

2. The cartridge for troponin I chromatography test paper according to claim 1, characterized in that the protective shell (13) is adsorbed to the upper surface of the housing (10).

3. The cartridge for troponin I chromatography test paper according to claim 1, characterized in that the protective casing (13) is of opaque construction; sliding grooves (111) are formed in the inner walls of the two sides of the accommodating cavity (11), and a notch (14) communicated with the sliding grooves (111) is formed in one end of the shell (10); one end of the protective shell (13) penetrates through the notch (14) and then is connected with the sliding groove (111) in a sliding manner; when the detection card body (1) is used, the protective shell (13) is received in the containing cavity (11) and covers the sample adding pad (21).

4. The card shell for troponin I chromatography test paper according to claim 3, characterized in that the protective shell (13) has a plate-like structure having adsorbability on one surface.

5. The clamping shell for the troponin I chromatography test paper according to claim 3, wherein the protective shell (13) is provided with a limiting block (131), and the side wall of the cavity (11) is provided with a stop block (112); the limiting block (131) is matched with the stop block (112) to limit one end of the protective shell (13) to be separated from the sliding groove (111).

6. The cartridge for troponin I chromatography test strips according to claim 3, characterized in that when said protective casing (13) is received in said receptacle (11), said protective casing (13) covers the result display area of said test strip (20).

7. The cartridge for chromatographic test strips of troponin I according to claim 3, characterized in that said casing (10) comprises an upper casing (101), a lower casing (102); the upper shell (101) and the lower shell (102) are clamped together to form the containing cavity (11).

8. The cartridge for troponin I chromatography test paper according to claim 7, characterized in that the slide groove (111) is provided on the upper case (101).

9. The card shell for troponin I chromatography test paper according to claim 3, characterized in that the protective shell (13) is provided with a foolproof marking; when the protective shell (13) is received in the accommodating cavity (11), the fool-proof mark indicates that the detection card body (1) is waste through the window of the shell (10).

10. A test card, comprising:

a test strip (20) for detecting troponin I;

a card shell for a troponin I chromatography test strip according to any one of claims 1 to 9; the test strip (20) is arranged in the cavity (11); the sample adding pad (21) of the test strip (20) corresponds to the sample adding hole (12) in position.