CN215811966U

CN215811966U - Chromosome dispersion instrument

Info

Publication number: CN215811966U
Application number: CN202122128036.6U
Authority: CN
Inventors: 郭江山; 郭鹏宇; 张娇娇
Original assignee: Beijing Beikang Medical Laboratory Co ltd
Current assignee: Beijing Beikang Medical Laboratory Co ltd
Priority date: 2021-09-03
Filing date: 2021-09-03
Publication date: 2022-02-11
Anticipated expiration: 2031-09-03

Abstract

The utility model relates to a chromosome dispersion appearance, including the shell, the shell is located including the device portion that is located the top and the gaseous portion that is located the below a plurality of accommodation holes have been seted up to one side lateral wall of gaseous portion, and the inside sliding connection that is located the accommodation hole has places the box, be located the inside of shell for the top of placing the box is provided with ventilative box, first bleeder vent has been seted up to the below of ventilative box, the second bleeder vent has been seted up to the lower surface of ventilative box. This application has the effect that makes the slide receive the wind-blowing comparatively even to improve the effect of final off-the-shelf quality.

Description

Chromosome dispersion instrument

Technical Field

The present application relates to the field of medical devices, and more particularly to chromosome dispersers.

Background

In the chemical detection process, in order to control the temperature and humidity during the chromosome preparation process and standardize the chromosome preparation process so as to obtain a uniformly dispersed metaphase mitosis phase, a slide containing cellular chromosomes is generally placed in a chromosome dispersing instrument.

The chromosome dispersor is used to perform the final evaporation in a well controlled environment to improve the quality of the metaphase of cellular chromosomes on the slide. The method is suitable for wall-pasting and suspension methods, and can be used for treating samples obtained from various culture methods, such as peripheral blood, bone marrow, amniotic cells, chorionic villi, etc.

Aiming at the related technologies, the inventor thinks that the current process of regulating and controlling the temperature and humidity of the slide by the chromosome dispersion instrument is generally towards the slide for blowing, and the existing method is generally to directly blow external air into the slide through an air inlet pipe, so that the air inlet effect is poor, the air inlet is uneven, and the effect of wind among a plurality of slides is uneven.

SUMMERY OF THE UTILITY MODEL

In order to make the slide receive the effect of blowing comparatively even to improve final finished product's quality, this application provides chromosome dispersion appearance.

The chromosome dispersion meter provided by the application adopts the following technical scheme:

chromosome dispersion appearance, including the shell, the shell is including the device portion that is located the top and the gaseous portion that is located the below, is located a plurality of accommodation holes have been seted up to one side lateral wall of gaseous portion, and the inside sliding connection that is located the accommodation hole has places the box, be located the inside of shell for the top of placing the box is provided with ventilative box, first bleeder vent has been seted up to the below of ventilative box, the second bleeder vent has been seted up to the lower surface of ventilative box.

Through adopting above-mentioned technical scheme, through the inside with external air suction to the shell, and with the inside of gas suction to ventilative box, and then make the air be full of the inside of ventilative box, be located the inside gas of ventilative box and can arrange the inside of placing the box from first bleeder vent for the even inside of placing the box that enters into of gas, thereby the slide receives the effect of blowing comparatively even, improves final off-the-shelf quality.

Optionally, the fixed plate is fixedly arranged in the placing box, the clamping plates are arranged on one side of the fixed plate in parallel, the clamping plates are connected with the placing box in a sliding mode, a linkage structure for driving the clamping plates to move synchronously is arranged on one side of each clamping plate, and the locking structure is arranged on one side of each clamping plate.

Through adopting above-mentioned technical scheme, through removing the grip block, adjust the interval between grip block and the fixed plate, and then carry out the centre gripping through grip block and fixed plate to the slide, be convenient for fix the slide in the inside of placing the box.

Optionally, the linkage structure comprises a linkage plate fixedly connected to the clamping plate, one end of the linkage plate is fixedly connected to the clamping plate, and the other end of the linkage plate is abutted to the adjacent linkage plate.

By adopting the technical scheme, the clamping plates are moved, so that the clamping plates drive the linkage plates fixedly connected with the clamping plates to move, the linkage plates can drive the clamping plates abutted against the linkage plates to synchronously move, and the clamping plates can drive the clamping plates to synchronously move by moving one clamping plate, so that the operation of an operator is facilitated.

Optionally, the locking structure including with grip block sliding connection's locking piece, the grip block for the locking hole has been seted up to the position of locking piece, the locking piece is located the inside of locking hole, the locking piece is close to the one end at the hole bottom in locking hole is provided with the elastic component, the locking piece is including the first skew wall that the slope set up and the first fixed wall of vertical setting, place the box for a plurality of locking grooves have been seted up to the position of locking piece, the locking groove including with the second skew wall that first skew wall is relative, and with the fixed wall of the second that first fixed wall set up relatively.

Through adopting above-mentioned technical scheme, through removing the grip block, make the grip block can drive the locking piece and remove, the relative butt of first locking wall and the second locking wall of locking piece, and the relative butt of first fixed wall and second fixed wall, when the grip block orientation is close to fixed plate one side and removes, second locking wall and first locking wall relative slip, and then make the locking piece retract the inside of locking groove, thereby make the locking piece enter into the position of next locking groove, promote the inside that the locking piece stretched into the locking groove through the elastic component, thereby make the locking piece can only move towards the one side that is close to the fixed plate, can not move towards the one side that deviates from the fixed plate, in order to realize the centre gripping to the slide.

Optionally, a guide rod is arranged at a position of the placing box relative to the clamping plate, the guide rod is horizontally arranged and is fixedly connected with the placing box, and the guide rod is slidably connected with the clamping plate.

Through adopting above-mentioned technical scheme, through setting up the guide bar for the grip block can reduce the crooked possibility of grip block through the direction of guide bar at relative movement's in-process, and then the operating personnel of being convenient for promotes the grip block and removes.

Optionally, the inside fixedly connected with cooling tube of ventilative box, the one end and the inlet tube of cooling tube communicate relatively, and the other end and the outlet pipe of cooling tube communicate relatively.

Through adopting above-mentioned technical scheme, through setting up the cooling tube for water flows in the inside of cooling tube from the inlet tube, and flows out from the outlet pipe, thereby cools down the inside temperature of ventilative box through the cooling tube, adjusts the inside temperature of ventilative box.

Optionally, the cooling pipe is fixedly connected with an atomizing nozzle, and the atomizing nozzle is communicated with the cooling pipe relatively.

Through adopting above-mentioned technical scheme, can be vaporific blowout with the inside water of cooling down through atomizer and fuse inside the air, and then flow into the inside of placing the box from the second bleeder vent to be convenient for adjust the humidity of placing the box inside.

Optionally, a collecting box is arranged below the placing box, the collecting box is relatively communicated with the placing box, and the collecting box is relatively communicated with the device part through a communicating pipe.

Through adopting above-mentioned technical scheme, through the inside of placing the inside gas escape of box and collecting the box, and then make the inside gas of collecting the box from the inside escape into device portion of communicating pipe for cool down the device of air to device portion inside.

In summary, the present application includes at least one of the following beneficial technical effects:

1. chromosome dispersion appearance, including the shell, the shell is including the device portion that is located the top and the gaseous portion that is located the below, is located a plurality of accommodation holes have been seted up to one side lateral wall of gaseous portion, and the inside sliding connection that is located the accommodation hole has places the box, be located the inside of shell for the top of placing the box is provided with ventilative box, first bleeder vent has been seted up to the below of ventilative box, the second bleeder vent has been seted up to the lower surface of ventilative box.

2. Through removing the grip block for the grip block drives rather than fixed connection's linkage board and removes, and then the linkage board can drive rather than the grip block synchronous motion of butt, thereby can drive a plurality of grip blocks synchronous motion through removing a grip block, the operating personnel's of being convenient for operation.

3. Through removing the grip block, make the grip block can drive the locking piece and remove, the relative butt of first locking wall and the second locking wall of locking piece, and the relative butt of first fixed wall and second fixed wall, when the grip block orientation is close to fixed plate one side and removes, second locking wall and first locking wall relative slip, and then make the locking piece retract the inside of locking groove, thereby make the locking piece enter into the position of next locking groove, promote the inside that the locking piece stretched into the locking groove through the elastic component, thereby make the locking piece can only move towards the one side that is close to the fixed plate, can not move towards the one side that deviates from the fixed plate, in order to realize the centre gripping to the slide.

Drawings

FIG. 1 is a schematic view showing the overall configuration of a chromosome dispersion meter in an embodiment of the present application;

FIG. 2 is a sectional view of a chromosome dispersion meter in an embodiment of the present application;

FIG. 3 is a schematic diagram showing the internal structure of a chromosome scatterer in the example of the present application;

FIG. 4 is a schematic view showing the internal structure of a vented cassette of a chromosome dispersion apparatus in an embodiment of the present application;

FIG. 5 is a schematic view showing a holding structure of the chromosome scatterometer in the embodiment of the present application;

FIG. 6 is a schematic view showing a lock structure of the chromosome scatterometer in the embodiment of the present application;

fig. 7 is a sectional view of a locking structure of the chromosome scatterometer in the embodiment of the present application.

Description of reference numerals: 1. a housing; 11. a partition plate; 12. a device section; 13. a gas portion; 14. an accommodation hole; 2. placing the box; 21. a second air hole; 22. a groove; 23. a guide groove; 231. a guide bar; 3. a cooling assembly; 31. a ventilation box; 311. a first air vent; 32. an intake pump; 321. an air inlet pipe; 322. air inlet branch pipes; 33. a cooling pipe; 331. a water inlet pipe; 332. a water outlet pipe; 333. an atomizing spray head; 4. a circulation component; 41. a collection box; 42. a communicating pipe; 421. drying the box; 5. a clamping structure; 51. a fixing plate; 52. a clamping plate; 521. a linkage plate; 6. a locking structure; 61. a locking block; 611. a first inclined wall; 612. a first fixed wall; 62. a locking hole; 63. a spring; 64. a locking groove; 641. a second inclined wall; 642. a second fixed wall.

Detailed Description

The present application is described in further detail below with reference to figures 1-7.

The embodiment of the application discloses a chromosome dispersator. Referring to fig. 1 and 2, the chromosome dispersion instrument includes a housing 1, a partition plate 11 horizontally disposed inside the housing 1, the partition plate 11 being fixedly connected to the housing 1, and the housing 1 being divided into an upper device part 12 and a lower gas part 13 by the partition plate 11.

Four receiving holes 14 are formed in the side wall of the housing 1 at positions corresponding to the gas portions 13, and the storage box 2 is slidably connected to the side wall of the housing 1 at positions corresponding to the receiving holes 14. A cooling component 3 is arranged above the placing box 2, and a circulating component 4 is arranged below the placing box 2.

Referring to fig. 3 and 4, the cooling module 3 includes a ventilation box 31 located above the placing box 2, the ventilation box 31 is of a rectangular hollow structure and located on the housing 1, a suction pump 32 is fixedly connected to the lower portion of the suction pump 32, and the suction pipe 321 is communicated with the suction pump 32 relatively, so that the suction pump 32 can suck outside air into the inside of the suction pipe 321.

Lie in the intake pipe 321 and be close to the one end level of placing box 2 and be provided with the branch pipe 322 that admits air, admit air and divide pipe 322 and ventilative box 31 one-to-one, admit air and divide pipe 322 and intake pipe 321 fixed connection and relative intercommunication, and admit air and divide fixed connection and relative intercommunication between pipe 322 and the ventilative box 31. So that the air intake pump 32 draws the outside air into the inside of the air intake pipe 321, and draws the air inside the air intake pipe 321 into the inside of the permeable box 31 through the air intake branch pipe 322.

A plurality of first bleeder vents 311 have been seted up to the lower surface that is located ventilative box 31, and the upper surface opening that places box 2 sets up, and the lower surface that is located place box 2 has seted up second bleeder vent 21 for the inside air that is located ventilative box 31 can blow in the inside of placing box 2 from first bleeder vent 311, and then blows off from the position of second bleeder vent 21.

The inside level that is located ventilative box 31 is provided with cooling tube 33, and cooling tube 33 is hollow lamellar structure, and cooling tube 33 is snakelike distribution, is located the inside cooling tube 33 end to end of four ventilative boxes 31 and links to each other in proper order. A water inlet pipe 331 is fixedly connected to one side of the housing 1, and the water inlet pipe 331 is fixed and relatively communicated with one end of the cooling pipe 33. A water outlet pipe 332 is fixedly connected to one side of the shell 1 departing from the water inlet pipe 331, and the water outlet pipe 332 is communicated with the other end of the cooling pipe 33. From inlet tube 331 towards the inside injected water of cooling tube 33, and water enters into the inside of cooling tube 33 from inlet tube 331, cools down the inside air of ventilative box 31, and then water is discharged from the inside of outlet pipe 332.

The lower surface fixedly connected with a plurality of atomizer 333 that are located cooling tube 33, atomizer 333 communicates with cooling tube 33's inside relatively for the hydroenergy that is located cooling tube 33 inside can be from the position blowout of atomizer 333, and then to the inside humidification that carries out of ventilative box 31, arranges moist air into the inside of placing box 2 through first bleeder vent 311, and then carries out humidification to the slide.

The circulation unit 4 includes a collecting box 41 disposed below the placing box 2, the collecting box 41 is disposed at an opening corresponding to the placing box 2, and the collecting box 41 is fixedly connected to the housing 1, so that the gas discharged from the placing box 2 can be collected by the collecting box 41, and the collecting box 41 is communicated with the device unit 12 via a communication pipe 42, so that the gas in the collecting box 41 can be discharged into the device unit 12 via the communication pipe 42. The communicating pipe 42 is vertically arranged and penetrates the partition plate 11 and is relatively fixedly connected.

The drying box 421 is fixedly connected to the communication pipe 42, the communication pipe 42 and the drying box 421 are relatively fixed and relatively communicated, and the drying agent for absorbing moisture is filled in the drying box 421, so that the moist air in the collecting box 41 can be dried by the absorption of the drying agent, and the damage of the moist air to the elements is reduced.

Referring to fig. 5 and 6, a clamping structure 5 is disposed inside the placing box 2, a plurality of grooves 22 are disposed on the lower surface of the placing box 2, and the grooves 22 are rectangular structures. Clamping structure 5 is including being located the fixed plate 51 of placing the vertical setting of box 2 for the one end of recess 22, fixed plate 51 with place between the box 2 fixed connection, and be located the recess 22 and deviate from the vertical grip block 52 that is provided with in one side of fixed plate 51, grip block 52 is located the inside of recess 22, grip block 52 with place between the box 2 sliding connection.

When the placing box 2 is completely positioned in the housing 1, one side of the clamping plate 52, which faces away from the fixing plate 51, is provided with a linkage plate 521, one end of the linkage plate 521 is fixedly connected with the clamping plate 52, and the other end of the linkage plate 521 is in relative contact with the adjacent clamping plate 52. When one of the clamping plates 52 is pushed to move towards one side close to the fixed plate 51, the fixed plate 51 can drive the linkage plate 521 to move, and then the linkage plate 521 can synchronously drive the adjacent clamping plate 52 to synchronously move.

The lower surface that is located the inner wall of placing box 2 has seted up guide way 23, and guide way 23 is seted up along the line direction from between fixed plate 51 and the grip block 52, and the inside level that is located guide way 23 is provided with guide bar 231, the both ends of guide bar 231 respectively with place fixed connection between the box 2, and sliding connection between guide bar 231 and the grip block 52.

Referring to fig. 6 and 7, a locking structure 6 is disposed between the clamping plate 52 and the placing box 2, the locking structure 6 includes a horizontally disposed locking block 61, a locking hole 62 is horizontally disposed at a position of the clamping plate 52 relative to the locking block 61, and the locking block 61 is disposed inside the locking hole 62 and is connected in a relatively sliding manner. A spring 63 is horizontally arranged inside the locking hole 62, one end of the spring 63 is fixedly connected with the clamping plate 52, and the other end of the spring 63 is fixedly connected with the locking block 61.

The end of the locking block 61 facing away from the spring 63 comprises a first inclined wall 611 arranged obliquely, the first inclined wall 611 being inclined gradually towards the side facing away from the holding plate 52 from the side close to the holding plate 51 to the side facing away from the holding plate 51. A first fixed wall 612 is vertically provided on a side of the first inclined wall 611 adjacent to the fixed plate 51.

The position of the placing box 2 corresponding to the groove 22 is provided with a plurality of locking grooves 64, the locking grooves 64 are equidistantly arranged along the direction of a connecting line from the fixing plate 51 to the clamping plate 52, the locking grooves 64 comprise a second inclined wall 641 obliquely arranged close to one side of the fixing plate 51, the oblique direction of the second inclined wall 641 is the same as that of the first inclined wall 611, and a second fixing wall 642 is vertically arranged on one side of the second inclined wall 641 departing from the fixing plate 51.

When the clamping plate 52 is slid toward the side of the fixed plate 51, the locking block 61 and the locking groove 64 are brought into relative contact, and when the clamping plate 52 is moved, the second inclined wall 641 and the first inclined wall 611 are slid relative to each other, and the first fixed wall 612 and the second fixed wall 642 are brought into relative contact, so that the clamping plate 52 can only be moved toward the side close to the fixed plate 51, and by the relative engagement of the first fixed wall 612 and the second fixed wall 642, the clamping plate 52 cannot be moved toward the side away from the fixed plate 51.

The implementation principle of the chromosome dispersion instrument in the embodiment of the application is as follows: through the inside of admitting air pump 32 with external air suction to intake pipe 321, and then intake pipe 321 blows in gas in the inside of ventilative box 31, and gaseous cooling through cooling tube 33, and drives the inside that is located the inside aqueous vapor of cooling tube 33 and melts into the air through atomizer 333 to make and be located the inside moist microthermal air of ventilative box 31 and can enter into the inside of placing box 2 and carry out the humidification cooling to the slide.

The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims

1. Chromosome dispersion appearance, its characterized in that: including shell (1), shell (1) is including device portion (12) that is located the top and gaseous portion (13) that are located the below, is located a plurality of accommodation holes (14) have been seted up to one side lateral wall of gaseous portion (13), and the inside sliding connection who is located accommodation hole (14) has places box (2), and the inside that is located shell (1) for the top of placing box (2) is provided with ventilative box (31), first bleeder vent (311) have been seted up to the below of ventilative box (31), second bleeder vent (21) have been seted up to the lower surface of ventilative box (31).

2. The chromosome scatterometer of claim 1, wherein: the fixed plate (51) that is provided with in the inside of placing box (2), the one side parallel arrangement that is located fixed plate (51) have grip block (52), grip block (52) with place sliding connection between box (2), one side of grip block (52) is provided with the linkage structure of a plurality of grip block (52) synchronous motion of drive, one side of grip block (52) is provided with locking structure (6).

3. The chromosome scatterometer of claim 2, wherein: the linkage structure comprises a linkage plate (521) fixedly connected to the clamping plate (52), one end of the linkage plate (521) is fixedly connected to the clamping plate (52), and the other end of the linkage plate (521) is abutted to the adjacent linkage plate (521).

4. The chromosome scatterometer of claim 2, wherein: the locking structure (6) comprises a locking block (61) slidably connected with a clamping plate (52), the clamping plate (52) is provided with a locking hole (62) relative to the position of the locking block (61), the locking block (61) is located inside the locking hole (62), one end, close to the hole bottom of the locking hole (62), of the locking block (61) is provided with an elastic piece, the locking block (61) comprises a first inclined wall (611) obliquely arranged and a first fixed wall (612) vertically arranged, the position of the placing box (2) relative to the locking block (61) is provided with a plurality of locking grooves (64), and each locking groove (64) comprises a second inclined wall (641) opposite to the first inclined wall (611) and a second fixed wall (642) opposite to the first fixed wall (612).

5. The chromosome scatterometer of claim 2, wherein: the position of the placing box (2) relative to the clamping plate (52) is provided with a guide rod (231), the guide rod (231) is horizontally arranged, the guide rod (231) is fixedly connected with the placing box (2), and the guide rod (231) is slidably connected with the clamping plate (52).

6. The chromosome scatterometer of claim 1, wherein: the inside fixedly connected with cooling tube (33) of ventilative box (31), the one end and inlet tube (331) of cooling tube (33) communicate relatively, and the other one end and outlet pipe (332) of cooling tube (33) communicate relatively.

7. The chromosome dispersion instrument according to claim 6, wherein: fixedly connected with atomizer (333) on cooling tube (33), atomizer (333) with cooling tube (33) communicates relatively.

8. The chromosome scatterometer of claim 1, wherein: a collecting box (41) is arranged below the placing box (2), the collecting box (41) is relatively communicated with the placing box (2), and the collecting box (41) is relatively communicated with the device part (12) through a communicating pipe (42).