CN215743532U

CN215743532U - Multi-specification centrifuge tube adaptive sampling mechanism for digital PCR

Info

Publication number: CN215743532U
Application number: CN202121618208.1U
Authority: CN
Inventors: 凌云峰; 戴子豪; 王雅琦; 张华�; 李琛
Original assignee: Suzhou Precigenome Co ltd
Current assignee: Suzhou Precigenome Co ltd
Priority date: 2021-07-16
Filing date: 2021-07-16
Publication date: 2022-02-08
Anticipated expiration: 2031-07-16

Abstract

The utility model provides a multi-specification centrifuge tube adaptive sampling mechanism for digital PCR, which comprises a sampling cover and a guide rod vertically arranged on the sampling cover, wherein one side of the guide rod is connected with a sampling needle through a slide block, the upper end of the sampling cover is provided with a sampling port, and the sampling needle moves up and down in the sampling port along the axial direction of the guide rod through the slide block. The utility model has the beneficial effects that: the sample injection needle with the adjustable position realizes the adaptation of centrifuge tubes with different depths. Simultaneously, realized the adaptation of different specification centrifuging tubes through switching subassembly, the practicality is high, has indirectly improved detection efficiency.

Description

Multi-specification centrifuge tube adaptive sampling mechanism for digital PCR

Technical Field

The utility model belongs to the technical field of fluid control, and particularly relates to a multi-specification centrifuge tube adaptive sampling mechanism for digital PCR.

Background

In the field of chemical analysis, a liquid to be analyzed is usually placed in a centrifuge tube, and then the liquid in the centrifuge tube is sampled and analyzed by a corresponding analyzer or detector. However, the specification of the centrifuge tube is various, such as 50mL, 15mL, 2mL, 1.5mL, etc., different sample injection covers are required to be adapted to the centrifuge tubes with different specifications, and the depths of the centrifuge tubes with different specifications are different, and the length of the sample injection needle of the existing sample injection assembly is fixed, so that the centrifuge tube cannot be adapted well, and the detection efficiency is indirectly low.

SUMMERY OF THE UTILITY MODEL

In order to solve the defects of the prior art, the utility model provides a multi-specification centrifuge tube adaptive sampling mechanism for digital PCR.

The purpose of the utility model is realized by the following technical scheme:

digital PCR is with many specifications centrifuging tube adaptation sampling mechanism, including advancing the sample lid, set up perpendicularly in advance the guide arm that the sample was covered, one side setting of guide arm is connected with a syringe through the slider, the outlet has been seted up to the upper end of advancing the sample lid, the syringe passes through the slider is followed the axial of guide arm is in up-and-down motion in the outlet.

Preferably, the lateral part of the sample injection cover is provided with an air inlet, and the lower part of the sample injection cover is provided with an internal thread for connecting a centrifugal tube.

Preferably, a sealing assembly used for keeping sealing with the sample injection needle is arranged on the sample outlet of the sample injection cover.

Preferably, the sealing assembly comprises a sealing ring embedded in the sample injection cover and a gland used for compressing the sealing ring.

Preferably, the sample injection device further comprises an adapter assembly connected in the sample injection cover.

Preferably, the adapter assembly comprises an adapter seat in threaded connection with the sample injection cover and an adapter ring selectively connected in the adapter seat.

Preferably, the adapter ring is in threaded connection with the adapter base.

Preferably, the inner diameter of the adapter ring is matched with the centrifuge tube cover to be connected.

The utility model has the beneficial effects that: the sample injection needle with the adjustable position realizes the adaptation of centrifuge tubes with different depths. Simultaneously, the adaptation of different specification centrifuging tubes has further been realized through switching subassembly, and the practicality is high, has indirectly improved detection efficiency.

Drawings

FIG. 1: the structure of the utility model is shown schematically.

FIG. 2: the utility model has a schematic use structure diagram when the adapter is provided.

FIG. 3: the partial enlarged structure of A in FIG. 2 is schematically shown.

Wherein, 1 advance kind lid, 2 guide arms, 3 sliders, 31 regulating blocks, 4 advance kind needles, 6 centrifuging tubes, 12 internal threads, 51 gland, 5 sealing washers, 7 adapter, 71 through-hole inner walls, 72 outer surfaces.

Detailed Description

The utility model discloses a multi-specification centrifuge tube adaptive sampling mechanism for digital PCR, which is shown in a combined figure 1-figure 3 and comprises a sampling cover 1 and a guide rod 2 vertically arranged on the sampling cover 1, wherein a slide block 3 is arranged on the guide rod 2, and the slide block 3 is screwed and adjusted with the guide rod 2 through an adjusting block 31. Be connected with injection needle 4 on the other end of slider 3, injection needle 4 with guide arm 2 parallel arrangement, through slider 3 is in removal on the guide arm 2 can drive injection needle 4 is along the axial direction of guide arm 2 moves.

A sample outlet is formed in the upper end of the sample injection cover 1, a gas inlet 11 is formed in the side portion of the sample injection cover, and an internal thread 12 used for being connected with a centrifugal tube is arranged on the lower portion of the sample injection cover 1. The sample adding mode applicable to the utility model usually comprises a negative pressure extraction type or a positive pressure extraction type, and the specific sample adding steps are consistent with the prior art and are not the key points of the protection of the utility model, so the details are not repeated herein.

The bottom end of the sample injection needle 4 penetrates through the sample outlet and enters a centrifugal tube 6 connected with the sample injection cover 1. The slide block 3 can be adjusted to quickly adjust the depth of the sample injection needle 4 entering the centrifuge tube 6.

In order to avoid the situation that the sampling needle 4 is not sealed between the sampling ports when moving, a sealing component used for keeping sealing between the sampling needles is arranged on the sampling port of the sampling cover. In this embodiment, the sealing assembly includes a sealing ring 5 embedded in the sample outlet of the sample injection cover 1 and a pressing cover 51 for pressing the sealing ring. The gland 51 can also be connected with the sample injection cover 1 in a threaded connection mode. Of course, the sealing assembly may also be integrated, that is, the pressing cover 51 is pressed and connected to the sample outlet of the sample injection cover 1 by an elastic material.

For the different specification size's of adaptation centrifuging tube, advance kind mechanism still including connect in advance the switching subassembly in the lid 1. The adapter assembly comprises an adapter 7 in threaded connection with the sample injection cover 1.

Adapter 7 is the cylindricality body that the through-hole was seted up to the center, adapter 7 surface 72 is processed there is the external screw thread, and through-hole inner wall 71 is processed there is the internal thread, the external screw thread with advance kind lid 1 internal thread phase-match, internal surface 71 internal thread is used for fixed with the centrifuging tube 6 of treating the connection. When 6 specifications of centrifuging tube are great, then need not to use adapter 7, can be directly through the internal thread connection of advancing kind lid 1. When, 6 specifications of centrifuging tube are less, can be connected with the centrifuging tube of little specification through increasing adapter 7, because the centrifuging tube specification is various, for the different centrifuging tube of adaptation, adapter 7 can be provided with the through-hole diameter of multiple difference, can change as required. Of course, it is also possible to selectively connect adapter rings in the adapter seat 7, i.e. to adapt centrifugal tubes 6 of different specifications by adapting the inner diameters of different adapter rings. The adapter ring and the adapter seat 7 are connected in the same way as the adapter seat 7 and the sample injection cover 1, and are connected in a threaded manner.

The utility model well solves the defect that the prior art can not be adapted to the sample introduction of centrifuge tubes with various specifications and different depths, assists the subsequent detection and analysis and effectively improves the detection efficiency.

Finally, it should be noted that: the terms "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

The above embodiments are only used to illustrate the technical solution of the present invention, but not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims

1. Digital PCR is with many specifications centrifuging tube adaptation sampling mechanism, its characterized in that: including advance kind of lid, set up perpendicularly in advance kind guide arm on covering, one side of guide arm sets up and is connected with a sample injection needle through the slider, the outlet has been seted up to the upper end of advancing kind of lid, the sample injection needle passes through the slider is followed the axial of guide arm is in up-and-down motion in the outlet.

2. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 1, which is characterized in that: the air inlet has been seted up to the lateral part of advancing the sample lid, the lower part of advancing the sample lid is provided with the internal thread that is used for connecting the centrifuging tube.

3. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 2, wherein: and a sealing assembly used for keeping sealing between the sampling needle and the sampling port of the sampling cover is arranged on the sampling port of the sampling cover.

4. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 3, wherein: the sealing assembly comprises a sealing ring embedded in the sample injection cover and a gland used for compressing the sealing ring.

5. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 2, wherein: the sample injection device also comprises an adapter assembly connected in the sample injection cover.

6. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 5, wherein: the adapter assembly comprises an adapter seat in threaded connection with the sample injection cover and an adapter ring selectively connected in the adapter seat.

7. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 6, wherein: the adapter ring is in threaded connection with the adapter seat.

8. The digital PCR multi-specification centrifuge tube adaptive sampling mechanism of claim 7, which is characterized in that: the inner diameter of the adapter ring is matched with the centrifugal pipe cover to be connected.