CN215728215U - Full-automatic sample adding system - Google Patents
Full-automatic sample adding system Download PDFInfo
- Publication number
- CN215728215U CN215728215U CN202121925163.2U CN202121925163U CN215728215U CN 215728215 U CN215728215 U CN 215728215U CN 202121925163 U CN202121925163 U CN 202121925163U CN 215728215 U CN215728215 U CN 215728215U
- Authority
- CN
- China
- Prior art keywords
- tray
- unit
- placing
- slide
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model discloses a full-automatic sample adding system, which comprises: the base is provided with a horizontal supporting plate and a vertical plate; the sample reagent placing box is arranged on the horizontal support plate and is used for placing a sample and a reagent; the incubation unit is arranged on the horizontal supporting plate, and the inlet end of the incubation unit is provided with a tray placing position and a pushing mechanism for pushing the tray to move forwards; the inlet end of the oscillating cleaning unit is connected with the outlet end of the incubation unit and comprises a shaking table mechanism, a conveying mechanism, a cleaning mechanism and a blowing mechanism; the air drying unit is arranged on the horizontal supporting plate and is used for air-drying the tray and the slide sent out from the vibration cleaning unit; three-dimensional moving mechanism sets up on the riser, has clamping jaw and liquid-transfering needle, and the clamping jaw is used for snatching the tray and puts the position and send the tray to air-dry the unit with it to put into the tray from shaking cleaning unit, and the liquid-transfering needle is used for placing tray slide on the position to the tray and pours into sample and reagent into. The utility model has the advantages of low cost, stable operation, high sample adding precision and high efficiency.
Description
Technical Field
The utility model relates to the technical field of trace sample detection and sample adding, in particular to a full-automatic sample adding system.
Background
When an organization mechanism such as a hospital, a third-party detection mechanism, a disease control center and the like detects a trace sample, the trace sample needs to be pretreated, and the steps comprise reagent filling, incubation, oscillation cleaning, air drying and the like. At present, manual operation is mostly adopted in the work, the process is complicated, time and labor are consumed, the standardized operation degree is not high, and the detection accuracy is influenced.
Disclosure of Invention
In order to solve the above problems, the present invention provides a full-automatic sample adding system, which specifically adopts the following technical scheme:
the full-automatic sample adding system comprises
The base comprises a horizontal supporting plate and a vertical plate;
the sample reagent placing box is arranged on the horizontal support plate and is used for placing a sample and a reagent;
the incubation unit is arranged on the horizontal supporting plate, and a tray placing position and a pushing mechanism for pushing the tray to move forwards are arranged at the inlet end of the incubation unit;
the inlet end of the oscillation cleaning unit is connected with the outlet end of the incubation unit, and the oscillation cleaning unit comprises a shaking table mechanism for placing a tray, a conveying mechanism for moving the tray, a cleaning mechanism for cleaning a slide on the tray and a blowing mechanism for blowing away cleaning liquid on the slide;
the air drying unit is arranged on the horizontal supporting plate and is used for air-drying the tray and the slide sent out from the vibration cleaning unit;
the three-dimensional moving mechanism is arranged on the vertical plate and is provided with a clamping jaw and a liquid transferring needle, the clamping jaw is used for grabbing a tray, putting the tray into the tray placing position and conveying the tray to the air drying unit from the vibration cleaning unit, and the liquid transferring needle is used for injecting a sample and a reagent into a tray glass slide on the tray placing position.
The sample reagent placement cassette is disposed near the inlet end of the incubation unit.
The incubation unit comprises a water bath heating mechanism and an upper cover auxiliary electric heating mechanism.
The moving direction of the tray in the incubation unit is perpendicular to the moving direction of the tray in the oscillation cleaning unit.
The shaking table mechanism comprises a cam driven by a motor, the cam is connected with the shaking table through a top rod, the shaking table is of a flat plate structure provided with a placing groove, and trays in the placing groove are sequentially arranged along the moving direction of the trays.
The cleaning mechanism comprises a horizontal mounting plate driven by a lifting horizontal pushing mechanism, a liquid injection needle and a liquid suction needle are arranged on the horizontal mounting plate, and the liquid injection needle and the liquid suction needle are located at one end, far away from the glass slide, above the tray.
And a pinch valve is arranged on a liquid injection pipeline of the liquid injection needle.
The purging mechanism comprises a fan and an air duct connected with the fan, and the outlet end of the air duct is arranged at the other end of the glass slide corresponding to the liquid injection needle and the liquid suction needle.
The tray is provided with a plurality of slide placing positions, the slide placing positions are sequentially arranged along the longitudinal direction of the tray, one end, close to the air duct, of each slide placing position is provided with an elastic clamping piece, the bottom of the other end is provided with an inclined guide plate, and the middle part of the left side wall and the right side wall of each slide placing position is of a flat plate structure.
The inlet end of the incubation unit is also provided with a photographing unit for detecting a sample adding result.
The full-automatic sample adding system is used for pretreatment operation of trace sample detection, and can realize periodic full-automatic operation of processes of reagent adding, incubation, oscillation cleaning, air drying and the like according to the adding type of a reagent; in addition, in the process, the cleaning solution is added mildly, so that the condition that the sample on the slide is cleaned by mistake can be effectively prevented; during air drying, the wind power is uniformly distributed, the air drying effect of large liquid drops on the glass slide is obvious, and a good foundation is laid for the subsequent shortening of the drying time; the liquid injection pipeline is additionally provided with the pinch valve, so that liquid injection can be conveniently controlled, liquid dripping can be conveniently blocked, and the air-dried glass slide is prevented from being dripped and wetted again. The utility model has the advantages of low cost, stable operation, high sample adding precision and high efficiency.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a schematic structural view of the sample reagent housing box of fig. 1.
Fig. 3 is a schematic structural view of the three-dimensional moving mechanism in fig. 1.
Fig. 4 is a schematic view of the structure of the incubation unit of fig. 1.
FIG. 5 is a schematic structural diagram of the oscillating cleaning unit in FIG. 1.
Fig. 6 is a schematic view showing the structure of the tray with the slide glass mounted thereon in fig. 3 and 4.
Detailed Description
The following describes embodiments of the present invention in detail with reference to the drawings, which are implemented on the premise of the technical solution of the present invention, and give detailed implementation manners and specific working procedures, but the scope of the present invention is not limited to the following embodiments.
As shown in fig. 1-6, the full-automatic sample adding system of the present invention mainly comprises a base 1, a sample reagent placing box 2, an incubation unit 3, a vibration cleaning unit 4, an air drying unit 5 and a three-dimensional moving mechanism 6.
Specifically, the base 1 comprises a horizontal support plate and a vertical plate, the sample reagent placing box 2, the incubation unit 3, the oscillation cleaning unit 4 and the air drying unit 5 are all arranged on the horizontal support plate, and the three-dimensional moving mechanism 6 is arranged on the vertical plate.
As shown in fig. 2, the sample reagent storing box 2 has a circular groove at the front end for storing the reagent bottle 201 and the quality control bottle 202, a strip-shaped groove at the rear end for storing the sample rack 203, and the sample tube 204 in the sample rack 203 contains the sample. The one end of above-mentioned bar recess still is provided with the sensor that targets in place, can trigger the sensor when the bar recess is put into to sample frame 203, lights the pilot lamp that is located the sample frame 230 rear end simultaneously, plays the indicative function.
Before detection, the sample is dripped on a glass slide, different reagents are added in a plurality of times for incubation treatment, and reaction residues after incubation are cleaned before adding the reagents each time. The slide is usually a ten-well slide 7 as shown in fig. 6, and in order to perform batch detection, a plurality of ten-well slides 7 are placed on a tray 8 (see fig. 6) at the same time. Set up a plurality of slide that arrange in order along tray 8's lengthwise direction on the tray 8 and put the position, the one end that each slide put the position all is provided with elasticity card 801, and the bottom of the other end then is provided with slope guide plate 802, and each slide put the position about lateral wall middle part be flat structure 803.
Since the sample reagent housing box 2 is spaced apart from the drop position, a three-dimensional moving mechanism is required. As shown in fig. 3, the three-dimensional moving mechanism 6 is mounted on the vertical plate, and has an X-direction moving arm 601 perpendicular to the vertical plate, a first Y-direction moving arm 602 and a second Y-direction moving arm 603 are mounted on the X-direction moving arm 601, a first Z-direction moving arm 604 is mounted on the first Y-direction moving arm 602, a second Z-direction moving arm 605 is mounted on the second Y-direction moving arm 603, a clamping jaw 606 is mounted at the end of the first Z-direction moving arm 604, and a liquid transferring needle 607 is mounted at the end of the second Z-direction moving arm 605. The gripper jaws 606 are used to grasp the tray 8 and place it into the tray placement 301 at the inlet end of the incubation unit 3, and to transport the tray 8 from the shake-wash unit 4 to the air-drying unit 5, and the pipetting needle 607 is used to inject the sample and reagent onto the ten slides 7 on the tray placement site 301. For ease of priming, the sample reagent holding cassette 2 is typically mounted near the inlet end of the incubation unit 3.
As shown in FIG. 4, the incubation unit 3 comprises an X-direction channel 302 arranged on the right side of a tray 301, a water bath heating mechanism is arranged at the bottom of the X-direction channel 302, an upper cover auxiliary electric heating mechanism 303 is arranged at the top of the X-direction channel 302, and the tray 8 stays for a certain time after entering the X-direction channel 302 to complete incubation. The left side of the tray placement 301 is mounted with a pusher mechanism 304 for pushing the tray 8 into the X-direction passage 302 and to the right in the X-direction. In order to prevent the samples and the reagents from being leaked and added to the ten-well slides 7, a photographing unit is further installed at the front end of the top of the X-direction channel 302 and comprises a light source 901 and a camera 902, when the liquid transferring needle 607 finishes adding the samples to all the ten-well slides 7 in the tray 8 on the tray placing position 301, the light source 901 is turned on, the camera 902 is used for photographing judgment, the sample adding condition is fed back to the control center, and if the sample adding condition is abnormal, sample adding operation is performed, and the like.
The exit end of incubation unit 3 links up and installs and shake cleaning unit 4, and both perpendicular installations make in the incubation unit 3 along X to tray 8 that removes move after getting into to shake cleaning unit 4 along Y to removing. As shown in fig. 5, the oscillating cleaning unit 4 includes a table mechanism for placing the tray 8, a conveying mechanism for moving the tray 8, a cleaning mechanism for cleaning the ten-hole slides 7 on the tray 8, and a blowing mechanism for blowing off the cleaning liquid on the ten-hole slides 7. The rocking bed mechanism comprises a cam driven by a motor, the cam is connected with a rocking bed 411 through a top rod, the rocking bed 411 is of a flat plate structure provided with a placing groove 412, and the trays 8 in the placing groove 412 are sequentially arranged along the Y direction. The conveying mechanism typically employs a timing belt driven paddle (not shown in fig. 5) mounted on the left side of the horizontal mounting plate 431 for pushing the tray 8 forward. The cleaning mechanism comprises a horizontal mounting plate 431 driven by a lifting and horizontal pushing mechanism, a liquid injection needle 432 and a liquid suction needle 433 are mounted on the horizontal mounting plate 431, and the liquid injection needle 432 and the liquid suction needle 433 are both positioned at one end, far away from a liquid hole position of 7 points of the ten-hole glass slide, above the tray 8. In order to control the liquid injection and prevent the liquid left in the pipeline from dropping due to other factors such as motion vibration and the like, and prevent the air-dried ten-hole slide 7 from being wet again, a pinch valve 434 is arranged on the liquid injection pipeline of the liquid injection needle 432. The purging mechanism comprises a fan 441 and an air duct 442 connected with the fan, and the outlet end of the air duct 442 is arranged at the other end of the liquid hole position of the ten-hole slide 7 corresponding to the liquid injection needle 432 and the liquid suction needle 433 and is used for blowing away large cleaning liquid drops remained on the surface of the ten-hole slide 7 after cleaning liquid suction so as to be beneficial to the next air drying operation. Above-mentioned wiper mechanism and sweep the reciprocating motion of mechanism in shaking table 411 top of shaking cleaning unit 4, because annotate liquid needle 432 and keep away from in the some liquid hole sites of ten hole slides 7, consequently, the liquid of taking pressure can not directly contact with the material in some liquid hole sites when annotating the liquid to can fully avoid taking pressure the liquid to wash away the emergence of bad phenomena such as sample and reactant. Secondly, the left side wall and the right side wall of a glass slide placing position in the tray 8 adopt a flat plate structure, so that the undesirable phenomena of wind shielding, turbulence and the like of the blowing mechanism during blowing can be avoided, and the blowing speed of large liquid drops can be accelerated.
The air-drying unit 5 is provided with a fan with a heating wire for air-drying the tray 8 and the ten-hole slide 7 sent out from the shake-washing unit 4. After the tray 8 and ten well slides 7 are air dried, if it is necessary to add the reagents again, they are moved to the tray by the clamping jaws 606 and placed 301, again added dropwise, incubated, washed and air dried; if the preparation work has been completed, it is moved to the tray storage position by the gripping claw 606. After all the trays 8 are transferred to the tray storage positions, the corresponding pretreatment process is finished, and the subsequent routine waste liquid discharge and maintenance process is carried out on the tray.
It should be noted that in the description of the present invention, terms of orientation or positional relationship such as "front", "rear", "left", "right", "vertical", "horizontal", "inner", "outer", etc., are based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
Claims (10)
1. The utility model provides a full-automatic application of sample system which characterized in that: comprises that
The base comprises a horizontal supporting plate and a vertical plate;
the sample reagent placing box is arranged on the horizontal support plate and is used for placing a sample and a reagent;
the incubation unit is arranged on the horizontal supporting plate, and a tray placing position and a pushing mechanism for pushing the tray to move forwards are arranged at the inlet end of the incubation unit;
the inlet end of the oscillation cleaning unit is connected with the outlet end of the incubation unit, and the oscillation cleaning unit comprises a shaking table mechanism for placing a tray, a conveying mechanism for moving the tray, a cleaning mechanism for cleaning a slide on the tray and a blowing mechanism for blowing away cleaning liquid on the slide;
the air drying unit is arranged on the horizontal supporting plate and is used for air-drying the tray and the slide sent out from the vibration cleaning unit;
the three-dimensional moving mechanism is arranged on the vertical plate and is provided with a clamping jaw and a liquid transferring needle, the clamping jaw is used for grabbing a tray, putting the tray into the tray placing position and conveying the tray to the air drying unit from the vibration cleaning unit, and the liquid transferring needle is used for injecting a sample and a reagent into a tray glass slide on the tray placing position.
2. The fully automatic sample addition system according to claim 1, wherein: the sample reagent placement cassette is disposed near the inlet end of the incubation unit.
3. The fully automatic sample addition system according to claim 1, wherein: the incubation unit comprises a water bath heating mechanism and an upper cover auxiliary electric heating mechanism.
4. The fully automatic sample addition system according to claim 1, wherein: the moving direction of the tray in the incubation unit is perpendicular to the moving direction of the tray in the oscillation cleaning unit.
5. The fully automatic sample addition system according to claim 1, wherein: the shaking table mechanism comprises a cam driven by a motor, the cam is connected with the shaking table through a top rod, the shaking table is of a flat plate structure provided with a placing groove, and trays in the placing groove are sequentially arranged along the moving direction of the trays.
6. The fully automatic sample addition system according to claim 5, wherein: the cleaning mechanism comprises a horizontal mounting plate driven by a lifting horizontal pushing mechanism, a liquid injection needle and a liquid suction needle are arranged on the horizontal mounting plate, and the liquid injection needle and the liquid suction needle are located at one end, far away from the glass slide, above the tray.
7. The fully automatic sample addition system according to claim 6, wherein: and a pinch valve is arranged on a liquid injection pipeline of the liquid injection needle.
8. The fully automatic sample addition system according to claim 7, wherein: the purging mechanism comprises a fan and an air duct connected with the fan, and the outlet end of the air duct is arranged at the other end of the glass slide corresponding to the liquid injection needle and the liquid suction needle.
9. The fully automatic sample addition system according to claim 8, wherein: the tray is provided with a plurality of slide placing positions, the slide placing positions are sequentially arranged along the longitudinal direction of the tray, one end, close to the air duct, of each slide placing position is provided with an elastic clamping piece, the bottom of the other end is provided with an inclined guide plate, and the middle part of the left side wall and the right side wall of each slide placing position is of a flat plate structure.
10. The fully automatic sample addition system according to claim 1, wherein: the inlet end of the incubation unit is also provided with a photographing unit for detecting a sample adding result.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121925163.2U CN215728215U (en) | 2021-08-17 | 2021-08-17 | Full-automatic sample adding system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121925163.2U CN215728215U (en) | 2021-08-17 | 2021-08-17 | Full-automatic sample adding system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215728215U true CN215728215U (en) | 2022-02-01 |
Family
ID=79997175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121925163.2U Active CN215728215U (en) | 2021-08-17 | 2021-08-17 | Full-automatic sample adding system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215728215U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359523A (en) * | 2023-05-30 | 2023-06-30 | 深圳市第二人民医院(深圳市转化医学研究院) | Medical automatic sample split charging instrument and system |
-
2021
- 2021-08-17 CN CN202121925163.2U patent/CN215728215U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116359523A (en) * | 2023-05-30 | 2023-06-30 | 深圳市第二人民医院(深圳市转化医学研究院) | Medical automatic sample split charging instrument and system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2021138963A1 (en) | Fully automatic chemiluminescent immune analyzer | |
| US6368872B1 (en) | Apparatus and method for chemical processing | |
| KR900005608B1 (en) | Liquid sample handling apparatus and process | |
| US6299840B1 (en) | Automatic testing apparatus | |
| CN108614101B (en) | Magnetic particle full-automatic chemiluminescence immunoassay analyzer | |
| EP0703455A1 (en) | Analyzing apparatus having pipetting device | |
| CN215728215U (en) | Full-automatic sample adding system | |
| CA1144462A (en) | Discrete type automated chemical analytic apparatus | |
| CN114660308B (en) | Full-automatic excrement detection device and using method thereof | |
| CN115112912A (en) | Multi-project body fluid analyzer | |
| CN114354308A (en) | Full-automatic film-making dyeing and film-reading integrated machine | |
| CN108176336B (en) | High-flux coprecipitation synthesizer | |
| CN104713858A (en) | Automatic time-resolved fluorescence assay device and application method thereof | |
| CN215940721U (en) | Thermistor automatic check out system | |
| CN114752491A (en) | Gene extraction module and gene detection equipment | |
| JP2002340912A (en) | Dispenser | |
| CN114184801A (en) | A pipelined biochemical analysis appearance for detecting protoheme of histocyte | |
| CN210401440U (en) | PH value test system | |
| JP7281540B2 (en) | automatic analyzer | |
| CN112198834A (en) | Full-automatic liquid-transfering machine control system | |
| CN113267498A (en) | Basic-level full-automatic body fluid inspection platform and automatic body fluid analysis system | |
| CN113295856A (en) | High-throughput virus detection device and application thereof in detection of new coronavirus | |
| CN112697569A (en) | Full-automatic dilution instrument and liquid dilution method | |
| JP3778002B2 (en) | Dispensing device | |
| CN211576742U (en) | Full-automatic dilution instrument |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |