CN215654743U - Mixing arrangement for medicine solid preparation - Google Patents

Mixing arrangement for medicine solid preparation Download PDF

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Publication number
CN215654743U
CN215654743U CN202121934839.4U CN202121934839U CN215654743U CN 215654743 U CN215654743 U CN 215654743U CN 202121934839 U CN202121934839 U CN 202121934839U CN 215654743 U CN215654743 U CN 215654743U
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CN
China
Prior art keywords
mixing
mixing box
air inlet
inlet pipe
blower
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Active
Application number
CN202121934839.4U
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Chinese (zh)
Inventor
王守彬
吕敏
卜玉静
曹慧敏
刘宗银
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Ruian Pharmaceutical Co ltd
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Shandong Ruian Pharmaceutical Co ltd
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Priority to CN202121934839.4U priority Critical patent/CN215654743U/en
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Abstract

The utility model discloses a mixing device for a solid pharmaceutical preparation, which is suitable for a small-dose solid pharmaceutical preparation with the active ingredient or raw material drug accounting for less than or equal to 0.025 percent of the weight percentage of the preparation, and the mixing device can more easily and uniformly mix the small-dose active pharmaceutical ingredient and auxiliary material ingredients, so that the content of the raw material drug or the active ingredient in a final product is uniform, and the mixing device has important significance for controlling the quality of the solid pharmaceutical preparation.

Description

Mixing arrangement for medicine solid preparation
Technical Field
The utility model belongs to pharmaceutical production equipment, and particularly relates to a mixing device for a pharmaceutical solid preparation.
Background
The medicine solid preparation comprises tablets, granules, powder and the like, wherein mixing is an important process in the production of the medicine solid preparation, active medicine component powder and auxiliary material component powder are uniformly mixed, and the consistency of the content of active components in a final product is the basic guarantee of medicine safety and effectiveness. In the production of actual pharmaceutical solid preparations, whether the degree of mixing uniformity is satisfactory or not is determined by examining the distribution of the active substance in the powder. Therefore, whether the active medicine component powder and the auxiliary material component powder can be uniformly mixed at the early stage is the key of the subsequent production of the medicine solid preparation. Especially, the active medicine components with small dosage are not easy to be mixed with the auxiliary material components by the common mixing method, if the existing common mixing method, such as the equal quantity increasing method, is adopted for mixing, the time and the labor are wasted during the actual production, and the production cost is increased.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides a mixing device for a medicinal solid preparation, which solves the problem that the content of active ingredients of a final product is not uniform due to the fact that small-dose active medicinal ingredients are not easy to mix uniformly with auxiliary ingredients.
The technical scheme of the utility model is realized as follows:
the utility model provides a mixing arrangement for pharmaceutical solid preparation, includes the mixing box, its characterized in that: mixing box top is provided with inlet pipe A and inlet pipe B, be provided with screening dish in the mixing box, be connected with the air-blower through the air-supply line on the mixing box, mixing box bottom side is semi-circular, the mixing box bottom is provided with the hob, the hob extends to in the conveying pipeline that mixing box one side is connected.
The feed pipe A is filled with bulk drug powder, and the feed pipe B is filled with auxiliary material powder.
The screening disc is a vibration screening disc or an ultrasonic screening disc, and the screening disc is detachably connected to the inner wall of the mixing box through a spring. The screening disc is powered by a vibration mechanism or an ultrasonic mechanism.
The mixing box is connected with at least one blower through an air inlet pipe, the air inlet pipe of the blower is arranged at the upper part or the lower part of the screening disc, and preferably, the air inlet pipe of the blower is arranged at the lower part of the screening disc; when more than two blowers are provided, the blowers are preferably operated alternately in order to make the powder mixing more uniform.
The air inlet of the air inlet pipe is positioned in the mixing box and internally provided with a cloth bag, and when the air blower does not work, the cloth bag can shield the air inlet of the air inlet pipe in a falling state so as to prevent powder from being blown into the opposite air inlet pipe when the air blower works alternatively.
The screw rod is used for conveying the uniformly mixed powder to the subsequent working procedures through the conveying pipe, and tabletting, granulating and the like are carried out.
The air blower is characterized in that a heating device is arranged on an air inlet pipe of the air blower, and a hygrothermograph is arranged at an air inlet of the air inlet pipe. According to actual conditions, with the air inlet properly heating when needs, the wet thermometer can better monitor the air inlet to prevent that the powder from taking place the caking phenomenon because of self reason.
The box of mixing box is the cuboid, the bottom side is semi-circular, so adopt such structure in the bottom, because can adapt to with the hob operation time for carry the material to next process better when mixing more evenly. Correspondingly, the conveying pipeline can be a circular pipeline and also can be a semicircular pipeline.
The mixing device is suitable for small-dose drug solid preparations with the active ingredients accounting for less than or equal to 0.025 percent of the weight of the preparation.
The mixing device provided by the utility model can be used for mixing a small-dose active pharmaceutical ingredient and an auxiliary ingredient more easily and uniformly, so that the content of the active pharmaceutical ingredient or the active ingredient in a final product is uniform, and the mixing device has an important significance for controlling the quality of a pharmaceutical solid preparation product.
Drawings
FIG. 1 is a schematic view of the internal structure of the present invention;
FIG. 2 is a state diagram of the cloth bag in the intake of air in FIG. 1;
fig. 3 is a side view of the housing of fig. 1.
In the figure, 1 is a feeding pipe A, 2 is a spring, 3 is a hygrothermograph, 4 is a cloth bag, 5 is an air inlet pipe, 6 is a heating device, 7 is a blower, 8 is a conveying pipe, 9 is a screw rod, 10 is a mixing box, 11 is a screening disc, and 12 is a feeding pipe B.
Detailed Description
The utility model provides a mixing arrangement for medicine solid preparation, includes mixing box 10, mixing box 10 top is provided with inlet pipe A1 and inlet pipe B12, be provided with screening dish 11 in the mixing box 10, be connected with air-blower 7 through air-supply line 5 on the mixing box 10, mixing box 10 bottom side is semi-circular, mixing box 10 bottom is provided with hob 9, hob 9 extends to in the conveying pipeline 8 of mixing box 10 one side connection.
The screening plate 11 is a vibration screening plate or an ultrasonic screening plate.
The screening disc 11 is detachably connected to the inner wall of the mixing box 10 through a spring 2.
At least one blower 7 is connected to the mixing box 10 through an air inlet pipe 5, the air inlet pipe 5 of the blower 7 is arranged at the upper part or the lower part of the sieving disc 11, and preferably, the air inlet pipe 5 of the blower 7 is arranged at the lower part of the sieving disc 11.
The air inlet of the air inlet pipe 5 is positioned in the mixing box 10 and is internally provided with a cloth bag 4.
And a heating device 6 is arranged on an air inlet pipe 5 of the blower 7.
And a hygrothermograph 3 is arranged at the air inlet of the air inlet pipe 5.
When mixing, the bulk drug powder of inlet pipe A1 and the auxiliary material powder of inlet pipe B12 are through getting into mixing box 10 through shale shaker 11 earlier, and air-blower 7 blows in the mixing box 10 through sack 4 with the air inlet of certain temperature for the powder in the space mixes more evenly, according to actual conditions, can adjust the wind speed, and air-blower 7 also can the intermittent type work, then the powder falls to the bottom of mixing box 10, is carried to next process while mixing by hob 9 drive powder.
The utility model is not specially explained, and all the prior art can be realized.

Claims (7)

1. The utility model provides a mixing arrangement for medicine solid preparation, includes mixing box (10), mixing box (10) top is provided with inlet pipe A (1) and inlet pipe B (12), its characterized in that: be provided with screening dish (11) in mixing box (10), be connected with air-blower (7) through air-supply line (5) on mixing box (10), mixing box (10) bottom side is semi-circular, mixing box (10) bottom is provided with hob (9), hob (9) extend to in mixing box (10) one side conveying pipeline (8) of connecting.
2. The mixing device for pharmaceutical solid preparations according to claim 1, characterized in that: the screening plate (11) is a vibration screening plate or an ultrasonic screening plate.
3. The mixing device for pharmaceutical solid preparations according to claim 1 or 2, characterized in that: the screening plate (11) is detachably connected to the inner wall of the mixing box (10) through a spring (2).
4. The mixing device for pharmaceutical solid preparations according to claim 1 or 2, characterized in that: the mixing box (10) is connected with at least one blower (7) through an air inlet pipe (5), and the air inlet pipe (5) of the blower (7) is arranged at the upper part or the lower part of the screening disc (11).
5. The mixing device for pharmaceutical solid preparations according to claim 4, characterized in that: the air inlet of the air inlet pipe (5) is positioned in the mixing box (10) and is internally provided with a cloth bag (4).
6. The mixing device for pharmaceutical solid preparations according to claim 4, characterized in that: and a heating device (6) is arranged on the air inlet pipe (5) of the air blower (7).
7. The mixing device for pharmaceutical solid preparations according to claim 4, characterized in that: and a hygrothermograph (3) is arranged at the air inlet of the air inlet pipe (5).
CN202121934839.4U 2021-08-18 2021-08-18 Mixing arrangement for medicine solid preparation Active CN215654743U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121934839.4U CN215654743U (en) 2021-08-18 2021-08-18 Mixing arrangement for medicine solid preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121934839.4U CN215654743U (en) 2021-08-18 2021-08-18 Mixing arrangement for medicine solid preparation

Publications (1)

Publication Number Publication Date
CN215654743U true CN215654743U (en) 2022-01-28

Family

ID=79953336

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202121934839.4U Active CN215654743U (en) 2021-08-18 2021-08-18 Mixing arrangement for medicine solid preparation

Country Status (1)

Country Link
CN (1) CN215654743U (en)

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