CN215640470U

CN215640470U - Glass slide dyeing liquid mixing spreading device

Info

Publication number: CN215640470U
Application number: CN202121442974.7U
Authority: CN
Inventors: 徐尚; 孙武举; 秦岩辉; 孙贵宾; 张硕; 魏娟; 任存邦; 王则宇; 杨红云
Original assignee: Autobio Diagnostics Co Ltd
Current assignee: Autobio Diagnostics Co Ltd
Priority date: 2021-06-28
Filing date: 2021-06-28
Publication date: 2022-01-25
Anticipated expiration: 2031-06-28

Abstract

The utility model discloses a glass slide staining solution uniformly mixing and spreading device, which comprises a horizontal frame, wherein a rectangular through hole is formed in the horizontal frame; the plurality of longitudinal support legs are uniformly distributed on the bottom surface of the horizontal frame, and the height of the longitudinal support legs is 0.2-0.5 mm; the pair of horizontal slideways are symmetrically arranged on the two long sides of the rectangular through hole; a painting and dyeing block horizontally and horizontally arranged in the rectangular through hole along the width direction, and the bottom surface of the painting and dyeing block is flush with the bottom surface of the horizontal frame; and the pair of sliding blocks are respectively positioned in the two horizontal sliding ways and are respectively and fixedly connected with the two ends of the coating and dyeing block to drive the coating and dyeing block to slide along the length direction of the horizontal sliding ways. The utility model has the advantages that the dye solution on the glass slide can be uniformly spread when the dye coating block horizontally slides by utilizing the capillary action force, the sample on the glass slide is ensured to be fully contacted with the dye solution, meanwhile, the dye coating block can not be contacted with the upper surface of the glass slide, the sample is prevented from being scraped, the dye solution is saved, the cross contamination is reduced, the glass slide dyeing quality is improved, and the follow-up microscopic observation is facilitated.

Description

Glass slide dyeing liquid mixing spreading device

Technical Field

The utility model relates to the technical field of laboratory slide dyeing, in particular to a device for uniformly mixing and spreading slide dyeing liquid.

Background

When biological slides are stained in clinical laboratories and pathology departments of hospitals, the slides need to be in full contact with staining solution so as to achieve good staining effect. At present, common dyeing methods include immersion dyeing, drop dyeing, spray dyeing and the like.

The immersion dyeing is to place the slide in a dyeing tank, a large amount of dyeing liquid is filled in the dyeing tank, and the sample area on the slide is uniformly covered with the dyeing liquid in an immersion mode and is fully contacted with the dyeing liquid. The back surface of the slide is also covered by the staining solution in the staining mode, microscopic examination of a subsequent instrument is influenced, the staining solution is wasted greatly, and the risk of cross contamination exists.

The dropping dyeing is that the slide is flatly placed in the instrument, the dyeing solution is dropped on the slide through a pipeline, and then the sample area is covered by the dyeing solution through vibration, shaking or centrifugation, or the surface of the slide is completely covered by a layer of the dyeing solution by increasing the filling amount of the dyeing solution. The smear is very inefficient in such a staining method, and the staining solution is required to be repeatedly dropped.

The spray dyeing is that the glass slide is vertically placed in an instrument, then the dyeing liquid is sprayed onto the glass slide in a mist form through a spray head in a high-pressure mode, usually a centrifugal turntable is adopted, 8-16 glass slides can be placed in the turntable, and continuous spraying is adopted during spraying. The dyeing mode cannot ensure that all the slides can be covered with the dyeing solution, and the vertical placement of the slides can cause the sprayed dyeing solution to flow down from the slides under the action of gravity, so that the staining solution is not attached to the slides, and the dyeing effect is poor; in addition, the amount of the staining solution used in spray staining is small, and the staining solution cannot be fully contacted with the specimen, so that the staining effect is poor; meanwhile, the spraying pressure is high, the staining solution can easily wash off the sample on the glass slide, and the liquid spraying device can easily cause the phenomenon of nozzle blockage once the liquid spraying device is not used for a long time, so that the reuse is influenced.

Disclosure of Invention

The utility model aims to provide a glass slide staining solution uniformly mixing and spreading device capable of uniformly smearing a film.

In order to achieve the purpose, the utility model can adopt the following technical scheme:

the utility model relates to a glass slide staining solution uniformly mixing and spreading device, which comprises:

a horizontal frame having a rectangular through hole having a width corresponding to that of the slide glass;

the plurality of longitudinal support legs are uniformly distributed on the bottom surface of the horizontal frame, have the height of 0.2-0.5 mm and are used for being fixedly supported on the upper surface of the glass slide;

the pair of horizontal slideways are symmetrically arranged on the two long sides of the rectangular through hole;

the dyeing block is horizontally and transversely arranged in the rectangular through hole along the width direction, and the bottom surface of the dyeing block is flush with the bottom surface of the horizontal frame; and

and the pair of sliding blocks are respectively positioned in the two horizontal sliding ways and are respectively and fixedly connected with two ends of the coating and dyeing block to drive the coating and dyeing block to slide along the length direction of the horizontal sliding ways.

Furthermore, an operating rod which extends out of the rectangular through hole upwards is arranged on the top surface of the painting and dyeing block.

Furthermore, the bottom surface of the painting and dyeing block is of a plane structure or a cambered surface structure which gradually protrudes from the long edges of the two sides to the middle part.

Furthermore, the cross section of horizontal slide is the rectangle structure, the slider be with horizontal slide assorted rectangle piece.

The utility model has the advantages that the horizontal frame is placed on the glass slide in parallel through the longitudinal support legs, the distance between the horizontal frame and the top surface of the glass slide is kept between 0.2 mm and 0.5mm, and a gap between the bottom surface of the painting and dyeing block and the upper surface of the glass slide is kept between 0.2 mm and 0.5mm all the time, so that a capillary phenomenon is generated, the painting and dyeing block can spread the dyeing liquid dripped on the glass slide uniformly when sliding horizontally by utilizing the capillary action force, the sample on the glass slide is ensured to be in full contact with the dyeing liquid, meanwhile, the painting and dyeing block can not be in contact with the upper surface of the glass slide, the sample is prevented from being scraped, the dyeing liquid is saved, the cross contamination is reduced, the glass slide dyeing quality is improved, and the follow-up microscopic examination and observation are facilitated.

Drawings

Fig. 1 is a schematic structural view of the present invention.

Fig. 2 is a right side view of fig. 1.

Figure 3 is a top view of figure 1 (with the slide removed).

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

As shown in fig. 1-3, the device for uniformly mixing and spreading a slide staining solution of the present invention comprises a horizontal frame 1, a plurality of longitudinal legs 2, a pair of horizontal slideways 3, a staining block 4 and a pair of sliders 5.

The horizontal frame 1 is of a rectangular structure, and the middle part of the horizontal frame 1 is provided with a rectangular through hole 7 with the width consistent with that of the glass slide 6; indulge 2 equipartitions of landing leg on the bottom surface of horizontal frame 1 for the top props on the upper surface of slide 6, and then makes horizontal frame 1 parallel support solid in slide 6 top, it is specific, it can be four to indulge landing leg 2, four are indulge the highly uniform of landing leg 2, be 0.2~0.5mm, and four are indulged 2 two liangs of a set of landing legs, two sets of 2 symmetries of indulging the landing leg set up on horizontal frame 1's both short sides, as long as guarantee that horizontal frame 1's length is less than or equal to slide 6's length this moment, just can ensure four and indulge the landing leg 2 can be steady support solid on slide 6's upper surface.

The two horizontal sliding ways 3 are symmetrically arranged on two long sides of the rectangular through hole 7 (namely on the opposite inner side walls of the two long sides of the horizontal frame 1), the painting and dyeing block 4 is horizontally and horizontally arranged in the rectangular through hole 7 along the width direction, the two sliding blocks 5 are respectively positioned in the two horizontal sliding ways 3 and are respectively and fixedly connected with two ends of the painting and dyeing block 4 (namely, two sliding blocks 5 are respectively and fixedly connected with two ends of the painting and dyeing block 4), so that the sliding blocks 5 can drive the painting and dyeing block 4 to slide along the length direction of the horizontal sliding ways 3; of course, in order to make the painting and dyeing block 4 slide smoothly along the horizontal sliding path 3, the section of the horizontal sliding path 3 should be rectangular, and correspondingly, the sliding block 5 should be a rectangular block matched with the horizontal sliding path 3. The bottom surface of the painting and dyeing block 4 is a plane structure which is flush with the bottom surface of the horizontal frame 1, the bottom surface of the painting and dyeing block 4 can be designed into an arc surface structure which gradually protrudes from the long edges of the two sides to the middle part, the bottommost end of the arc surface structure is only required to be flush with the bottom surface of the horizontal frame 1, and when the painting and dyeing block 4 moves horizontally in the horizontal frame 1, the gap between the bottommost end of the painting and dyeing block and the upper surface of a glass slide 6 below is always kept to be 0.2-0.5 mm.

In addition, in order to facilitate manual sliding of the painting block 4 or pushing of the painting block 4 by an automatic dyeing apparatus, an operating lever 8 protruding upward from the rectangular through hole 7 may be provided on the top surface of the painting block 4.

When in actual use, the device is only required to be stably placed on a glass slide 6, then the dyeing block 4 is slid to one end of the rectangular through hole 7, then the glass slide 6 can be coated and the dye solution is dripped, when the dye solution is dripped on the glass slide 6, the dyeing block 4 can be slid, as the distance between the bottommost end of the dyeing block 4 and the upper surface of the glass slide 6 is always kept between 0.2 mm and 0.5mm, when the dyeing block 4 slides over the dye solution, a capillary phenomenon can be generated between the dyeing block 4 and the glass slide 6, at the moment, the dyeing block 4 can be easily driven by capillary force to uniformly spread the dye solution on the glass slide 6, so that the sample on the glass slide 6 is ensured to be fully contacted with the dye solution, and meanwhile, the dyeing block 4 can not be contacted with the upper surface of the glass slide 6 in the process of translational sliding, thereby avoiding the possibility of scraping the sample, saving the dye solution, reducing the cross contamination, the quality of slide staining can be improved, and the subsequent microscopic examination observation is facilitated.

Claims

1. The utility model provides a slide staining fluid mixing spreading device which characterized in that: comprises that

2. The device for uniformly mixing and spreading the slide staining solution according to claim 1, which is characterized in that: and an operating rod which extends upwards out of the rectangular through hole is arranged on the top surface of the painting and dyeing block.

3. The device for uniformly mixing and spreading the slide staining solution according to claim 1, which is characterized in that: the bottom surface of the painting and dyeing block is of a plane structure or a cambered surface structure which gradually bulges from the long edges of the two sides to the middle part.

4. The device for uniformly mixing and spreading the slide staining solution according to claim 1, which is characterized in that: the section of horizontal slide is the rectangle structure, the slider be with horizontal slide assorted rectangle piece.