CN215640442U - Body fluid sample carrier structure - Google Patents
Body fluid sample carrier structure Download PDFInfo
- Publication number
- CN215640442U CN215640442U CN202121465870.8U CN202121465870U CN215640442U CN 215640442 U CN215640442 U CN 215640442U CN 202121465870 U CN202121465870 U CN 202121465870U CN 215640442 U CN215640442 U CN 215640442U
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- China
- Prior art keywords
- carrier structure
- fluid sample
- sample carrier
- slide
- body fluid
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- 210000001124 body fluid Anatomy 0.000 title claims abstract description 44
- 239000010839 body fluid Substances 0.000 title claims abstract description 33
- 239000011521 glass Substances 0.000 claims abstract description 31
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 239000000853 adhesive Substances 0.000 claims description 9
- 230000001070 adhesive effect Effects 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 3
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 229920005372 Plexiglas® Polymers 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 9
- 239000000523 sample Substances 0.000 description 45
- 210000004027 cell Anatomy 0.000 description 10
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 230000004308 accommodation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Images
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- Sampling And Sample Adjustment (AREA)
Abstract
The present invention relates to a body fluid sample carrier structure. The sample carrier structure comprises a cavity cover and a glass slide for carrying a liquid sample, the surface of the glass slide is attached to the cavity cover, a round sample adding port is arranged in the middle of the cavity cover, a plurality of accommodating grooves with different heights, which are uniformly distributed around the sample adding port, are arranged on the bottom surface of the cavity cover facing the glass slide, all the accommodating grooves and the surface of the glass slide are respectively enclosed to form chambers with different heights for accommodating body fluid to be detected, the projection areas of all the accommodating grooves on the surface of the glass slide are equal, and the sample adding port is communicated with all the chambers at equal intervals. Before the detection, the body fluid is only required to be loaded to the sample carrier once to detect different types of cells, so that the steps are simplified, and the detection efficiency is improved.
Description
Technical Field
The utility model relates to a body fluid detection and analysis tool, in particular to a body fluid sample carrier structure.
Background
The general operation method of the blood cell image recognition analyzer is as follows: dripping a blood diluted sample into sample inlets of different volume cavities on a sample carrier by using a liquid transfer device, enabling the sample to uniformly enter a measurement cavity under the capillary action, and finally respectively carrying out image recognition on cell types in the different volume cavities by using a high-magnification objective lens assembly after the cells are settled on the surface of a substrate of the carrier. Due to the need to ensure accurate sample addition to each chamber, a pipettor is typically used to sequentially drop the blood sample into the inlet of each chamber and to allow it to sit for a period of time. The sample adding method is very complicated, and because the sample adding has time sequence, the cell sedimentation degree of each chamber is inconsistent, the detection efficiency and accuracy are influenced, and the improvement is needed.
SUMMERY OF THE UTILITY MODEL
The present invention is directed to overcome the above drawbacks of the prior art, and provides a structure of a body fluid sample carrier to simplify the steps of loading body fluid to a sample carrier, and improve the detection efficiency and accuracy.
In order to achieve the purpose, the utility model adopts the following technical scheme: the utility model provides a body fluid sample carrier structure, it includes the cavity lid and is used for the slide glass of carrier liquid sample, slide glass surface and the laminating of cavity lid, cavity lid intermediate position sets up a circular shape sample loading mouth, the cavity lid is equipped with the holding tank of a plurality of co-altitude around sample loading mouth evenly distributed towards the bottom surface of slide glass, all holding tanks enclose into the chamber that co-altitude held and wait to detect body fluid with the slide glass surface respectively, all holding tanks are equal at slide glass overhead projection area, the sample loading mouth communicates with all chamber equidistance.
The sample feeding port is a conical port with a small upper part and a big lower part.
All chambers are communicated with one annular channel and surround the annular channel, the sample adding port is arranged in the middle of the annular channel, and the sample adding port is communicated with all chambers at equal intervals through the annular channel.
The cavity cover is provided with a liquid outlet at the outer side of the accommodating groove, and the liquid outlet is communicated with the cavity.
The opening direction of the liquid outlet is parallel to the opening direction of the sample addition port. The outer edge of the upper surface of the cavity cover is provided with a liquid discharge ring groove, and all liquid discharge ports are communicated with the liquid discharge ring groove.
The area between adjacent holding tanks is the bonding area that is used for with slide glass fixed connection.
The adhesive area is fixedly connected with the glass slide through adhesive or double-sided adhesive.
The glass slide is made of transparent glass.
The cavity cover is made of organic glass.
The periphery of the bottom surface of the cavity cover facing the glass slide is provided with a coaming plate surrounding the glass slide.
Compared with the prior art, the utility model has the beneficial effects that: cover the holding tank that different heights but projection area is the same through the cavity and form the not chamber of co-altitude with the slide glass, just can fill to each chamber rapidly under capillary force after the body fluid sample pours into from the loading port, the not chamber of co-altitude is used for the detection of different kinds of cells, therefore the body fluid only need once only load the sample carrier alright carry out the detection of different kinds of cells or project, the step is simplified, detection efficiency obtains promoting. And because the projected areas among the chambers are the same and uniformly distributed, the flow of the body fluid is balanced and synchronous to the surrounding chambers, the flow is more stable and the synchronism is better, and the convenience of sample adding is further improved.
The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood, the present invention may be implemented according to the content of the description, and in order to make the above and other objects, features, and advantages of the present invention more apparent, the following detailed description will be given of preferred embodiments.
Drawings
Fig. 1 is an exploded view of a body fluid sample carrier structure of the present invention.
FIG. 2 is a cross-sectional view of a bodily fluid sample carrier structure of the present invention.
FIG. 3 is a perspective view of a body fluid sample carrier structure of the present invention.
FIG. 4 is a schematic view showing a state of use of the structure of a body fluid specimen carrier according to the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings and the detailed description.
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be connected or detachably connected or integrated; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above should not be understood to necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples described in this specification can be combined and combined by one skilled in the art.
This embodiment is a structure of a body fluid sample carrier, the specific structure of which is shown in FIGS. 1 to 3.
As shown in fig. 1 and 2, the body fluid sample carrier structure includes a circular chamber cover 20 and a circular slide 10. The circular glass slide 10 is used for bearing the body fluid sample and can be used for sedimentation of cells, so that the cells can be uniformly spread. The glass slide 10 is made of transparent glass material, and the glass material has excellent light transmittance. The cavity cover 20 is made of organic glass. The surface of the glass slide 10 is attached to the bottom surface of the cavity cover 20. The cavity cover 20 is provided with a shroud 25 surrounding the slide 10 toward the outer edge of the bottom surface of the slide 10.
As shown in FIGS. 1 and 2, a circular sample addition port 21 is provided at the center of the chamber cover 20. The sample addition port 21 is a tapered port with a small top and a large bottom. The bottom surface of the chamber cover 20 facing the slide 10 is provided with 6 receiving grooves 22 of different heights evenly distributed around the sample addition port 21. The heights of the 6 accommodation grooves 22 are 0.05mm, 0.1mm, 0.15mm, 0.2mm, 0.25mm, and 1mm, respectively. The projected areas of all the receiving grooves 22 on the surface of the slide 10 are equal. As shown in fig. 2, all the accommodating grooves 22 and the surface of the slide 10 respectively enclose chambers 220 for accommodating the body fluid to be detected at different heights, so that the chambers 220 have different volumes from each other and can be used for detecting and analyzing different types of cells. The sample addition port 21 is in equidistant communication with all the chambers 220. Specifically, as shown in FIG. 2, all chambers 220 are communicated with one annular channel 210 and surround the annular channel 210, and the sample injection port 21 is arranged in the middle of the annular channel 210, and the sample injection port 21 is communicated with all chambers 220 at equal intervals through the annular channel 210.
In other embodiments, other numbers of chambers greater than 1 may be provided.
As shown in fig. 1 and 2, the cavity cover 20 is provided with a liquid outlet 23 outside the housing groove 22, and the liquid outlets 23 are all communicated with the chamber 220. The drain port 23 serves to drain excess bodily fluid sample, equalizing the pressure of the fluid in the chamber 220. The opening of the drain port 23 is parallel to the opening of the sample addition port 21. As shown in fig. 2 and 3, the outer edge of the upper surface of the cavity cover 20 is provided with a liquid discharge ring groove 26, and all the liquid discharge ports 23 are communicated with the liquid discharge ring groove 26.
As shown in fig. 1, the area between adjacent receiving channels 22 is an adhesive area 24 for secure attachment to the slide 10. The adhesive region 24 is fixedly attached to the slide 10 by adhesive or double-sided tape.
Before body fluid measurement, a body fluid sample with a certain proportion is uniformly mixed, and then the body fluid sample is stably injected through the sample injection port 21 by a liquid transfer device. The body fluid sample will fill each chamber 220 rapidly under gravity and capillary force, and the excess body fluid sample will overflow from the liquid outlet 23 to the liquid discharge ring groove 26 until the liquid level is balanced. After settling, the cells of the body fluid will settle uniformly on the base surface of the slide 10, and subsequent measurement can be performed from bottom to top through the objective lens 30, as shown in fig. 4.
In this embodiment, the accommodating grooves 22 with different heights but the same projection areas on the cavity cover 20 and the glass slide 10 form the chambers 220 with different heights, so that the body fluid sample can be rapidly filled into each chamber 220 under the capillary force after being injected from the sample injection port 21, and the chambers 220 with different heights are used for detecting different types of cells, so that the body fluid can be detected by only once loading the body fluid onto the sample carrier, the steps are simplified, and the detection efficiency is improved.
The technical contents of the present invention are further illustrated by the examples only for the convenience of the reader, but the embodiments of the present invention are not limited thereto, and any technical extension or re-creation based on the present invention is protected by the present invention. The protection scope of the utility model is subject to the claims.
Claims (10)
1. A body fluid sample carrier structure is characterized by comprising a cavity cover and a glass slide for carrying a body fluid sample, wherein the surface of the glass slide is attached to the cavity cover, a circular sample adding port is arranged in the middle of the cavity cover, a plurality of accommodating grooves with different heights are uniformly distributed around the sample adding port and are arranged on the bottom surface of the cavity cover facing the glass slide, all the accommodating grooves and the surface of the glass slide are respectively enclosed to form chambers with different heights for accommodating body fluid to be detected, the projection areas of all the accommodating grooves on the surface of the glass slide are equal, and the sample adding port is communicated with all the chambers at equal intervals.
2. The bodily fluid sample carrier structure of claim 1, wherein the sample addition port is a tapered port having a small top and a large bottom.
3. The bodily fluid sample carrier structure of claim 1, wherein all of the chambers are in communication with and surround an annular channel, the sample addition port is disposed in the middle of the annular channel, and the sample addition port is in equidistant communication with all of the chambers through the annular channel.
4. The bodily fluid sample carrier structure of claim 1, wherein the cavity cover is provided with a liquid discharge port on an outer side of the holding tank, the liquid discharge port communicating with the chamber.
5. The bodily fluid sample carrier structure of claim 4, wherein the upper surface of the chamber cover is provided at an outer edge thereof with a liquid discharge groove, and all of the liquid discharge ports communicate with the liquid discharge groove.
6. The bodily fluid sample carrier structure of claim 1, wherein an area between adjacent receiving channels is an adhesive area for secure attachment to a slide.
7. The bodily fluid sample carrier structure of claim 6, wherein the adhesive region is fixedly attached to the slide by an adhesive or double sided tape.
8. The bodily fluid sample carrier structure of claim 1, wherein the chamber cover is provided with a shroud surrounding the slide toward an outer edge of a bottom surface of the slide.
9. The bodily fluid sample carrier structure of any one of claims 1-8, wherein the slide is a transparent glass material.
10. A bodily fluid sample carrier structure as claimed in any of claims 1-8 wherein the chamber cover is of plexiglass material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121465870.8U CN215640442U (en) | 2021-06-29 | 2021-06-29 | Body fluid sample carrier structure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121465870.8U CN215640442U (en) | 2021-06-29 | 2021-06-29 | Body fluid sample carrier structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215640442U true CN215640442U (en) | 2022-01-25 |
Family
ID=79946653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121465870.8U Active CN215640442U (en) | 2021-06-29 | 2021-06-29 | Body fluid sample carrier structure |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215640442U (en) |
-
2021
- 2021-06-29 CN CN202121465870.8U patent/CN215640442U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20250226 Address after: 518000, 7th Floor, Building 9, Tianliao Industrial Zone A, No. 2235 Tangchang Road, Tanglang Community, Taoyuan Street, Nanshan District, Shenzhen, Guangdong Province Patentee after: Shenzhen chenna Biotechnology Co.,Ltd. Country or region after: China Address before: 518000 floor 8, building 5, donghuayuan industrial plant, No. 120, Nanguang Road, Nanguang community, Nanshan street, Nanshan District, Shenzhen, Guangdong Patentee before: Shenzhen Yuanshi Medical Technology Co.,Ltd. Country or region before: China Patentee before: SHENZHEN SHENGMINGGU LIFE TECHNOLOGY Research Institute |
|
| TR01 | Transfer of patent right |