CN215610856U

CN215610856U - Be used for synthetic agitating unit that uses of polypeptide

Info

Publication number: CN215610856U
Application number: CN202121962662.9U
Authority: CN
Inventors: 曹芯; 金成�
Original assignee: Nanjing Hongren Pharmaceutical Technology Co ltd
Current assignee: Nanjing Hongren Pharmaceutical Technology Co ltd
Priority date: 2021-08-19
Filing date: 2021-08-19
Publication date: 2022-01-25
Anticipated expiration: 2031-08-19

Abstract

The utility model belongs to the field of polypeptide synthesis, and particularly relates to a stirring device for polypeptide synthesis, which comprises a linkage rod, wherein one side of the linkage rod is connected with a stirring rod through a screw, a transmission rod is arranged above the linkage rod, a motor is arranged above the transmission rod, one side of the transmission rod is provided with a bracket, one side of the bracket is penetrated with a transfusion tube, and one side of the transfusion tube is provided with a funnel; through the relation between transfer line and the motor, when using, can rotate through transfer line and the gangbar that the motor drove the below, thereby can control the puddler and rotate, thereby accomplish the intensive mixing to the polypeptide of inside, and the relation between motor and the support, the support plays the effect of fixed stay to the motor, the protection motor can not drop when using, and through the relation between funnel and the transfer line, when using, the phenomenon that can effectual control polypeptide body can not appear spilling, more convenient quick material loading.

Description

Be used for synthetic agitating unit that uses of polypeptide

Technical Field

The utility model relates to the field of polypeptide synthesis, in particular to a stirring device for polypeptide synthesis.

Background

Polypeptide synthesis is a solid-phase synthesis sequence which is generally synthesized from a C end, an amino end to an N end and a carboxyl end, the traditional polypeptide synthesis is called liquid-phase synthesis in solution, and the polypeptide needs to be stirred during synthesis, so that the application of polypeptide stirring devices is more and more, and since the solid-phase polypeptide synthesis method is developed and succeeded in 1963, the solid-phase method becomes a common technology in polypeptide and protein synthesis today through continuous improvement and perfection.

When the existing stirring device is used, the polypeptide in the existing stirring device cannot be fully stirred, the phenomenon of insufficient stirring exists, the whole device is inconvenient to move quickly when in use, and the whole device is inconvenient to detach and replace quickly and is inconvenient to overhaul quickly when in use;

therefore, a stirring device for polypeptide synthesis has been proposed to address the above problems.

SUMMERY OF THE UTILITY MODEL

In order to make up for the defects of the prior art, solve the problems that the internal polypeptide cannot be fully stirred, the stirring is not sufficient enough, the integral device is inconvenient to move quickly when in use, and the integral device is inconvenient to detach and replace quickly and is inconvenient to overhaul quickly when in use, the utility model provides the stirring device for polypeptide synthesis.

The technical scheme adopted by the utility model for solving the technical problems is as follows: the stirring device for polypeptide synthesis comprises a linkage rod, wherein one side of the linkage rod is connected with a stirring rod through a screw, a transmission rod is arranged above the linkage rod, a motor is arranged above the transmission rod, a bracket is arranged on one side of the transmission rod, a perfusion tube penetrates through one side of the bracket, a funnel is arranged on one side of the perfusion tube, a conduction tube is arranged below the perfusion tube, the front end of the stirring rod is attached with a cover body, and an observation window is attached to the front end of the cover body.

Preferably, the drain pipe has been run through to one side of the cover body, the top of drain pipe is provided with the valve, the below of the cover body is provided with the bottom plate, fixing bolt has been run through to the below of bottom plate, fixing bolt's below is provided with the base, through the relation between drain pipe and the valve, when using, thereby can change the discharge rate of valve control below drain pipe, it is very convenient to use.

Preferably, the front end laminating of base has the ventilating board, one side of ventilating board is provided with the hinge, one side of ventilating board is provided with the handle, the below fixedly connected with pillar of base, the below of pillar is provided with the leading wheel, through the relation between base and the ventilating board, when using, the ventilating board can continuously carry out quick ventilation to the base inside, and through the relation between base and the pillar, the condition that can not appear breaking away from when using, and safety in utilization obtains guaranteeing.

Preferably, the transmission rod passes through the motor and constitutes revolution mechanic, and is symmetrical about the axis of transmission rod between the support, through the relation between transmission rod and the motor, when using, drives the transmission rod through the motor and rotates, as the power source of stirring, and through the relation between support and the transmission rod, when using, can support the motor of top and stabilize work, and the left and right sides all has the support to support, the condition that the slope dropped can not appear.

Preferably, be detachable construction between puddler and the gangbar, and pass through screwed connection between gangbar and the transfer line, and the gangbar passes through the transfer line and constitutes revolution mechanic, and the quantity of puddler is three, through the relation between puddler and the gangbar, in the use later stage, is convenient for dismantle the washing to the puddler, and the quantity of puddler is three, when using, can the inside liquid of effectual control puddler carry out intensive mixing.

Preferably, the ventilating board passes through to constitute revolution mechanic between hinge and the base, and passes through screwed connection between handle and the ventilating board, through the relation between ventilating board and the hinge, when using, can effectual control ventilating board carry out the block and close, when using, can enough dispel the heat fast, also be convenient for open fast and overhaul fast to inside component.

Preferably, the axis is symmetrical about the base between the leading wheel, and is threaded connection between leading wheel and the pillar, through the relation between leading wheel and the base, when using, can effectual control leading wheel can control the device and carry out the quick travel, and through the relation between leading wheel and the pillar, when using, threaded connection is convenient for the later stage and is dismantled the change fast.

Preferably, the drain pipe constitutes through the structure through the cover body, and the cover body passes through to constitute detachable construction between bottom plate and fixing bolt and the base, through the relation between the drain pipe and the cover body, when using, the polypeptide liquid of the cover body inside can discharge through the drain pipe, and through the relation between bottom plate and the fixing bolt, overhauls the in-process in the later stage, can rotate fixing bolt and carry out quick dismantlement maintenance to the cover body of top.

The utility model has the advantages that:

1. according to the utility model, through the relationship between the transmission rod and the motor, when in use, the transmission rod and the linkage rod below the motor can be driven by the motor to rotate, so that the stirring rod can be controlled to rotate, the polypeptide in the device can be fully stirred, and the relationship between the motor and the bracket can be used, the bracket plays a role of fixing and supporting the motor, so that the motor is protected from falling off when in use, and through the relationship between the funnel and the infusion tube, when in use, the phenomenon that the polypeptide body leaks can be effectively controlled, the feeding is more convenient and rapid, when in use, the polypeptide to be stirred is firstly poured in through the funnel, then is transmitted through the infusion tube, and is guided into the interior of the cover body of the device through the conduction tube, and then the linkage rod in the cover body drives the stirring rod to stir, so that the purpose of stirring the polypeptide is achieved, then, the stirred polypeptide is discharged through a liquid outlet pipe, and the discharge rate can be controlled by rotating a valve;

2. according to the utility model, through the relationship between the cover body and the observation window, when in use, external workers can visually observe through the observation window, and through the relationship between the conduction tube and the infusion tube, when in use, the polypeptide in the cover body can be effectively controlled to be rapidly transmitted into the cover body, and the leakage condition can not occur in the feeding process.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.

FIG. 1 is a schematic cross-sectional view of the present invention;

FIG. 2 is a schematic front view of the present invention;

FIG. 3 is a schematic view of a linkage rod structure according to the present invention;

FIG. 4 is an enlarged view of the structure of FIG. 1 at A in accordance with the present invention;

fig. 5 is a schematic view of the funnel structure of the present invention.

In the figure: 1. a motor; 2. a transmission rod; 3. a support; 4. a linkage rod; 5. a stirring rod; 6. a valve; 7. a liquid outlet pipe; 8. fixing the bolt; 9. a guide wheel; 10. a pillar; 11. a base; 12. a base plate; 13. a conducting tube; 14. a funnel; 15. a transfusion tube; 16. an observation window; 17. a cover body; 18. a hinge; 19. a ventilation board; 20. a handle.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-5, a stirring device for polypeptide synthesis comprises a linkage rod 4, one side of the linkage rod 4 is connected with a stirring rod 5 through a screw, a transmission rod 2 is arranged above the linkage rod 4, a motor 1 is arranged above the transmission rod 2, a bracket 3 is arranged at one side of the transmission rod 2, a perfusion tube 15 penetrates through one side of the bracket 3, a funnel 14 is arranged at one side of the perfusion tube 15, a conduction tube 13 is arranged below the perfusion tube 15, a cover body 17 is attached to the front end of the stirring rod 5, an observation window 16 is attached to the front end of the cover body 17, when the stirring device works, through the relationship between the transmission rod 2 and the motor 1, when the stirring device is used, the transmission rod 2 and the linkage rod 4 below can be driven by the motor 1 to rotate, so that the stirring rod 5 can be controlled to rotate, the polypeptide inside can be fully stirred, and the relationship between the motor 1 and the bracket 3, when using, support 3 plays the effect of fixed stay to motor 1, protection motor 1 is when using, can not drop, and through the relation between funnel 14 and transfer line 15, when using, the phenomenon that can spill can not appear in effectual control polypeptide body, convenient quick material loading more, can and when using, at first the polypeptide that will stir passes through funnel 14 and pours into, rethread transfer line 15 transmits, the inside of the leading-in cover body 17 of rethread conduction pipe 13, the inside gangbar 4 of the cover body 17 of rethread drives puddler 5 and stirs, accomplish the purpose of stirring polypeptide, then, polypeptide after the stirring passes through drain pipe 7 discharges, and rotary valve 6 can control discharge rate.

This embodiment, one side of the cover body 17 is run through and is had drain pipe 7, and the top of drain pipe 7 is provided with valve 6, and the below of the cover body 17 is provided with bottom plate 12, and fixing bolt 8 has been run through to the below of bottom plate 12, and fixing bolt 8's below is provided with base 11, through the relation between drain pipe 7 and valve 6, when using, thereby can change valve 6 and control the discharge rate of below drain pipe 7, and it is very convenient to use.

In this embodiment, the front end of base 11 is laminated with ventilating board 19, one side of ventilating board 19 is provided with hinge 18, one side of ventilating board 19 is provided with handle 20, below fixedly connected with pillar 10 of base 11, the below of pillar 10 is provided with leading wheel 9, through the relation between base 11 and ventilating board 19, when using, ventilating board 19 can continuously carry out quick ventilation to base 11 inside, and through the relation between base 11 and pillar 10, when using, the condition that can not appear breaking away from, safety in utilization obtains guaranteeing.

This embodiment, transfer line 2 constitutes revolution mechanic through motor 1, and is symmetrical about the axis of transfer line 2 between the support 3, through the relation between transfer line 2 and the motor 1, when using, drives transfer line 2 through motor 1 and rotates, as the power source of stirring, and through the relation between support 3 and transfer line 2, when using, can support the firm work of motor 1 of top, and the left and right sides all has support 3 to support, the condition that the slope dropped can not appear.

This embodiment, be detachable construction between puddler 5 and the gangbar 4, and pass through threaded connection between gangbar 4 and the transfer line 2, and gangbar 4 passes through transfer line 2 and constitutes revolution mechanic, and the quantity of puddler 5 is three, through the relation between puddler 5 and the gangbar 4, in the use later stage, be convenient for dismantle the washing to puddler 5, and the quantity of puddler 5 is three, when using, can the effectual control puddler 5 fully stir the liquid of inside.

This embodiment, ventilation board 19 passes through to constitute revolution mechanic between hinge 18 and the base 11, and passes through screwed connection between handle 20 and the ventilation board 19, through the relation between ventilation board 19 and the hinge 18, when using, can effectual control ventilation board 19 carry out the block and close, when using, can enough dispel the heat fast, also be convenient for open fast and carry out quick maintenance to inside component.

This embodiment, the axis about base 11 is symmetrical between leading wheel 9, and is threaded connection between leading wheel 9 and the pillar 10, through the relation between leading wheel 9 and the base 11, when using, can effectual control leading wheel 9 control the device and carry out the rapid draing, and through the relation between leading wheel 9 and the pillar 10, when using, threaded connection is convenient for the later stage and is carried out quick dismantlement and change.

In this embodiment, drain pipe 7 constitutes through the structure through the cover body 17, and the cover body 17 passes through and constitutes detachable construction between bottom plate 12 and fixing bolt 8 and the base 11, through the relation between drain pipe 7 and the cover body 17, and when using, the inside polypeptide liquid of the cover body 17 can be discharged through drain pipe 7, and through the relation between bottom plate 12 and fixing bolt 8, in later stage maintenance process, can rotate fixing bolt 8 and carry out quick dismantlement maintenance to the cover body 17 of top.

The theory of operation, with the device before the use, at first pour into the polypeptide that needs to stir through funnel 14, the rethread transfer line 15 transmits, the inside of the cover body 17 of rethread conduction pipe 13 leading-in the device, the inside gangbar 4 of the rethread cover body 17 drives puddler 5 and stirs, accomplishes the purpose of stirring the polypeptide, then, the polypeptide after the stirring passes through drain pipe 7 and discharges, and rotary valve 6 can control discharge rate.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The foregoing shows and describes the general principles, essential features, and advantages of the utility model. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the utility model as claimed.

Claims

1. A stirring device for polypeptide synthesis is characterized in that: including gangbar (4), there is puddler (5) one side of gangbar (4) through screwed connection, the top of gangbar (4) is provided with transfer line (2), the top of transfer line (2) is provided with motor (1), one side of transfer line (2) is provided with support (3), one side of support (3) is run through has transfer line (15), one side of transfer line (15) is provided with funnel (14), the below of transfer line (15) is provided with conduction pipe (13), the front end laminating of puddler (5) has the cover body (17), the front end laminating of the cover body (17) has observation window (16).

2. The stirring device for polypeptide synthesis according to claim 1, wherein: drain pipe (7) has been run through to one side of the cover body (17), the top of drain pipe (7) is provided with valve (6), the below of the cover body (17) is provided with bottom plate (12), fixing bolt (8) have been run through to the below of bottom plate (12), the below of fixing bolt (8) is provided with base (11).

3. The stirring device for polypeptide synthesis according to claim 2, wherein: the front end laminating of base (11) has ventilating board (19), one side of ventilating board (19) is provided with hinge (18), one side of ventilating board (19) is provided with handle (20), the below fixedly connected with pillar (10) of base (11), the below of pillar (10) is provided with leading wheel (9).

4. The stirring device for polypeptide synthesis according to claim 1, wherein: the transmission rod (2) forms a rotating structure through the motor (1), and the brackets (3) are symmetrical relative to the central axis of the transmission rod (2).

5. The stirring device for polypeptide synthesis according to claim 1, wherein: the stirring rod (5) and the linkage rod (4) are of a detachable structure, the linkage rod (4) and the transmission rod (2) are connected through a screw, the linkage rod (4) forms a rotating structure through the transmission rod (2), and the number of the stirring rods (5) is three.

6. The stirring device for polypeptide synthesis according to claim 3, wherein: the ventilating plate (19) and the base (11) form a rotating structure through the hinge (18), and the handle (20) is connected with the ventilating plate (19) through screws.

7. The stirring device for polypeptide synthesis according to claim 3, wherein: the guide wheels (9) are symmetrical relative to the central axis of the base (11), and the guide wheels (9) are in spiral connection with the support columns (10).

8. The stirring device for polypeptide synthesis according to claim 2, wherein: the drain pipe (7) forms a penetrating structure through the cover body (17), and the cover body (17) forms a detachable structure through the bottom plate (12) and the fixing bolt (8) and the base (11).