CN215539887U - Preparation device of poly 4-methyl-1-pentene hollow fiber membrane for ECMO - Google Patents
Preparation device of poly 4-methyl-1-pentene hollow fiber membrane for ECMO Download PDFInfo
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- CN215539887U CN215539887U CN202120500544.XU CN202120500544U CN215539887U CN 215539887 U CN215539887 U CN 215539887U CN 202120500544 U CN202120500544 U CN 202120500544U CN 215539887 U CN215539887 U CN 215539887U
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- membrane
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- hollow fiber
- pentene
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- 239000012528 membrane Substances 0.000 title claims abstract description 142
- WSSSPWUEQFSQQG-UHFFFAOYSA-N 4-methyl-1-pentene Chemical compound CC(C)CC=C WSSSPWUEQFSQQG-UHFFFAOYSA-N 0.000 title claims abstract description 100
- 239000012510 hollow fiber Substances 0.000 title claims abstract description 62
- 238000002618 extracorporeal membrane oxygenation Methods 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title abstract description 16
- 239000003085 diluting agent Substances 0.000 claims abstract description 47
- 239000000463 material Substances 0.000 claims abstract description 26
- 238000000151 deposition Methods 0.000 claims abstract description 21
- 229920001971 elastomer Polymers 0.000 claims abstract description 17
- 230000008021 deposition Effects 0.000 claims abstract description 16
- 238000010791 quenching Methods 0.000 claims abstract description 16
- 230000000171 quenching effect Effects 0.000 claims abstract description 16
- 239000011248 coating agent Substances 0.000 claims abstract description 15
- 238000000576 coating method Methods 0.000 claims abstract description 15
- 238000002145 thermally induced phase separation Methods 0.000 claims abstract description 15
- 239000000654 additive Substances 0.000 claims abstract description 14
- 230000000996 additive effect Effects 0.000 claims abstract description 14
- 238000005266 casting Methods 0.000 claims abstract description 14
- 238000001816 cooling Methods 0.000 claims abstract description 14
- 238000009987 spinning Methods 0.000 claims abstract description 12
- 238000004804 winding Methods 0.000 claims abstract description 10
- 238000010438 heat treatment Methods 0.000 claims abstract description 4
- 238000002156 mixing Methods 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 abstract description 35
- 239000011148 porous material Substances 0.000 abstract description 28
- 238000009826 distribution Methods 0.000 abstract description 11
- 239000000203 mixture Substances 0.000 description 26
- 239000007789 gas Substances 0.000 description 25
- 238000001125 extrusion Methods 0.000 description 20
- 239000000243 solution Substances 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 229920000642 polymer Polymers 0.000 description 14
- 238000005191 phase separation Methods 0.000 description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 12
- 230000008569 process Effects 0.000 description 11
- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 10
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 10
- 230000004907 flux Effects 0.000 description 9
- -1 polypropylene Polymers 0.000 description 9
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 description 8
- 239000008280 blood Substances 0.000 description 8
- 239000000306 component Substances 0.000 description 8
- 238000009730 filament winding Methods 0.000 description 8
- 239000010410 layer Substances 0.000 description 8
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 239000007864 aqueous solution Substances 0.000 description 7
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- 238000012512 characterization method Methods 0.000 description 7
- 239000011247 coating layer Substances 0.000 description 7
- 239000000155 melt Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000004205 dimethyl polysiloxane Substances 0.000 description 6
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 6
- 238000002481 ethanol extraction Methods 0.000 description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 6
- 238000007493 shaping process Methods 0.000 description 6
- 239000000377 silicon dioxide Substances 0.000 description 6
- 235000012239 silicon dioxide Nutrition 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 5
- 238000012824 chemical production Methods 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 230000007547 defect Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 5
- 230000035699 permeability Effects 0.000 description 5
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 description 5
- 238000003672 processing method Methods 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 4
- 239000002131 composite material Substances 0.000 description 4
- 229910000365 copper sulfate Inorganic materials 0.000 description 4
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 4
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 239000000178 monomer Substances 0.000 description 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 238000010926 purge Methods 0.000 description 4
- PYGXAGIECVVIOZ-UHFFFAOYSA-N Dibutyl decanedioate Chemical compound CCCCOC(=O)CCCCCCCCC(=O)OCCCC PYGXAGIECVVIOZ-UHFFFAOYSA-N 0.000 description 3
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 3
- 230000003321 amplification Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000010622 cold drawing Methods 0.000 description 3
- 239000011162 core material Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 3
- 239000004088 foaming agent Substances 0.000 description 3
- 230000002209 hydrophobic effect Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 239000012982 microporous membrane Substances 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 229920000306 polymethylpentene Polymers 0.000 description 3
- 239000011116 polymethylpentene Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000001069 triethyl citrate Substances 0.000 description 3
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 3
- 235000013769 triethyl citrate Nutrition 0.000 description 3
- DQWPFSLDHJDLRL-UHFFFAOYSA-N triethyl phosphate Chemical compound CCOP(=O)(OCC)OCC DQWPFSLDHJDLRL-UHFFFAOYSA-N 0.000 description 3
- 229910000831 Steel Inorganic materials 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Natural products OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 239000002667 nucleating agent Substances 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- DDSDPQHQLNAGLJ-YEBWQKSTSA-N (2z)-6-(2-chlorophenyl)-2-[(4-methylpiperazin-4-ium-1-yl)methylidene]-8-nitro-4h-imidazo[1,2-a][1,4]benzodiazepin-1-one;methanesulfonate Chemical compound CS(O)(=O)=O.C1CN(C)CCN1\C=C/1C(=O)N2C3=CC=C([N+]([O-])=O)C=C3C(C=3C(=CC=CC=3)Cl)=NCC2=N\1 DDSDPQHQLNAGLJ-YEBWQKSTSA-N 0.000 description 1
- 206010051093 Cardiopulmonary failure Diseases 0.000 description 1
- 208000028399 Critical Illness Diseases 0.000 description 1
- 229920000459 Nitrile rubber Polymers 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
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- 238000004140 cleaning Methods 0.000 description 1
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- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 229920005560 fluorosilicone rubber Polymers 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000009998 heat setting Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
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- 239000003960 organic solvent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
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- 239000012466 permeate Substances 0.000 description 1
- 125000005498 phthalate group Chemical group 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
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- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229920006126 semicrystalline polymer Polymers 0.000 description 1
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- 238000000807 solvent casting Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
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- 229920002397 thermoplastic olefin Polymers 0.000 description 1
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- Artificial Filaments (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202120500544.XU CN215539887U (en) | 2021-03-09 | 2021-03-09 | Preparation device of poly 4-methyl-1-pentene hollow fiber membrane for ECMO |
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CN202120500544.XU CN215539887U (en) | 2021-03-09 | 2021-03-09 | Preparation device of poly 4-methyl-1-pentene hollow fiber membrane for ECMO |
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CN215539887U true CN215539887U (en) | 2022-01-18 |
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CN202120500544.XU Active CN215539887U (en) | 2021-03-09 | 2021-03-09 | Preparation device of poly 4-methyl-1-pentene hollow fiber membrane for ECMO |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114749036A (en) * | 2022-04-24 | 2022-07-15 | 天津大学 | Hollow fiber heterogeneous membrane and preparation method and application thereof |
CN114832649A (en) * | 2022-04-21 | 2022-08-02 | 天津大学温州安全(应急)研究院 | Poly 4-methyl-1-pentene hollow fiber membrane based on green diluent and preparation method and application thereof |
-
2021
- 2021-03-09 CN CN202120500544.XU patent/CN215539887U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114832649A (en) * | 2022-04-21 | 2022-08-02 | 天津大学温州安全(应急)研究院 | Poly 4-methyl-1-pentene hollow fiber membrane based on green diluent and preparation method and application thereof |
CN114749036A (en) * | 2022-04-24 | 2022-07-15 | 天津大学 | Hollow fiber heterogeneous membrane and preparation method and application thereof |
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20231119 Address after: 211800 No.1 yuansiwu, Jiangbei new district, Nanjing City, Jiangsu Province Patentee after: Cui Chaoliang Patentee after: Guo Baitao Address before: No. 30, Puzhu South Road, Jiangbei new district, Nanjing City, Jiangsu Province, 211816 Patentee before: NANJING University OF TECHNOLOGY |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20240104 Address after: Room 301, Building 015, No. 135 Zhangji Road, Kunshan Development Zone, Suzhou City, Jiangsu Province, 215333 Patentee after: Jiangsu Aike Film High tech Co.,Ltd. Address before: 211800 No.1 yuansiwu, Jiangbei new district, Nanjing City, Jiangsu Province Patentee before: Cui Chaoliang Patentee before: Guo Baitao |
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TR01 | Transfer of patent right |