CN215404164U

CN215404164U - Microfluid device for cell embedding

Info

Publication number: CN215404164U
Application number: CN202120823256.8U
Authority: CN
Inventors: 陈丽; 杨继建; 赵汝星; 何芹; 刘继东; 吕彬
Original assignee: Nolai Biomedical Technology Co ltd
Current assignee: Nolai Biomedical Technology Co ltd
Priority date: 2021-04-21
Filing date: 2021-04-21
Publication date: 2022-01-04
Anticipated expiration: 2031-04-21

Abstract

The utility model relates to the technical field of microfluid, and discloses a microfluid device for cell embedding, which comprises a bottom plate, wherein the top of the bottom plate is provided with a fixing mechanism, the outer side of the fixing mechanism is provided with an adjusting mechanism, and the top of the fixing mechanism is provided with a microfluid chip body; the fixing mechanism comprises a supporting bin, the inner top wall of the supporting bin is fixedly connected with two stabilizing assemblies which are fixedly connected with the top of the bottom plate, and a driving mechanism is arranged inside the supporting bin; the adjusting mechanism comprises two limiting bins, two screw rods and a sleeve rod, wherein the outer sides of the screw rods are in threaded connection with the sleeve rod, and the two opposite sides of the sleeve rod are fixedly connected with connecting blocks fixedly connected with the left side and the right side of the supporting bin respectively. This microfluid device for cell embedding can be used to carry out the centre gripping through fixed establishment to microfluid chip body and fix to can carry out the centre gripping to the microfluid chip body of equidimension not, strengthened the practicality.

Description

Microfluid device for cell embedding

Technical Field

The utility model relates to the technical field of microfluid, in particular to a microfluid device for cell embedding.

Background

Embedding is the process of encapsulating a powder or other bulk structure of a material to be embedded with an embedding agent (which may be organic plastics, metals, etc.) to provide performance support or chemical protection.

Need inject the cell into microfluid chip and carry out the embedding processing to the cell during cell embedding, current microfluid chip is inconvenient when using fixes it and highly can't adjust, uses inconveniently, so, provides a microfluid device for cell embedding and solves foretell problem.

SUMMERY OF THE UTILITY MODEL

Technical problem to be solved

Aiming at the defects of the prior art, the utility model provides the microfluid device for cell embedding, which has the advantages of convenience in fixing, convenience in adjustment and the like, and solves the problems that the existing microfluid chip is inconvenient to fix and adjust in height during use and is inconvenient to use.

(II) technical scheme

In order to realize the purposes of convenient fixation and convenient adjustment, the utility model provides the following technical scheme: a microfluid device for cell embedding comprises a bottom plate, wherein a fixing mechanism is arranged at the top of the bottom plate, an adjusting mechanism is arranged at the outer side of the fixing mechanism, and a microfluid chip body is arranged at the top of the fixing mechanism;

the fixing mechanism comprises a supporting bin, the inner top wall of the supporting bin is fixedly connected with two stabilizing assemblies which are fixedly connected with the top of the bottom plate, and a driving mechanism is arranged inside the supporting bin;

the adjusting mechanism comprises two limiting bins, the top of the bottom plate is movably connected with two screw rods, the outer sides of the screw rods are in threaded connection with loop bars, and the two loop bars are fixedly connected with the connecting blocks fixedly connected with the left side and the right side of the supporting bin respectively.

Further, actuating mechanism includes and supports the front inner wall in storehouse and back inner wall fixed connection's fixed plate, the top fixedly connected with quantity of fixed plate is four mounting panels, and the back is two the equal swing joint in one side that the mounting panel is close to the front mounting panel has one end to run through and extend to the positive pivot of front mounting panel, two the equal fixedly connected with in the outside of pivot is located the positive first worm wheel of mounting panel, two the equal fixedly connected with drive gear in the outside of pivot, the interior roof swing joint that supports the storehouse has quantity for two and with drive gear meshed's driving rack.

Further, the top fixedly connected with quantity of fixed plate is four limiting plates, and the left side is two the equal swing joint in inside of two limiting plates on limiting plate and right side has the first worm with first worm wheel meshing, two the driven awl tooth of the equal fixedly connected with in one side that first worm is relative, the positive swing joint who supports the storehouse has one end to run through and extend to the inside transmission shaft of support storehouse, the outside fixedly connected with of transmission shaft and the initiative awl tooth of driven awl tooth meshing, two the equal fixedly connected with one end in top of driving rack runs through and extends to the connecting rod that supports the storehouse top, two the equal fixedly connected with clamp splice in top of connecting rod.

Furthermore, the inner wall of the left side of the limiting bin is movably connected with a second worm with one end penetrating through and extending to the right side of the right limiting bin, and the outer sides of the two screws are fixedly connected with a second worm wheel meshed with the second worm.

Further, stabilize the subassembly including stabilizing telescopic link and stabilizing spring, four the same and the rectangle distribution of size of stabilizing the subassembly, four the mounting panel is the rectangle distribution.

Further, a sliding block is fixedly connected between one side, opposite to the transmission rack and the connecting rod, of the supporting bin, and a sliding rail which is connected with the sliding block in a sliding mode is fixedly connected to the inner top wall of the supporting bin.

Furthermore, a threaded through hole in threaded connection with the screw rod is formed in the sleeve rod, and a rotating button is fixedly connected to the right side of the second worm.

(III) advantageous effects

Compared with the prior art, the utility model provides a microfluid device for cell embedding, which has the following beneficial effects:

1. this microfluid device for cell embedding can be used to carry out the centre gripping through fixed establishment to microfluid chip body and fix to can carry out the centre gripping to the microfluid chip body of equidimension not, strengthened the practicality.

2. The microfluid device for embedding the cells can be used for adjusting the height of the microfluid chip body through the adjusting mechanism, and is convenient for users to use.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged view of portion A of FIG. 1 according to the present invention;

fig. 3 is a front view of the structure of the present invention.

In the figure: 1 bottom plate, 101 fixing plate, 102 mounting plate, 103 rotating shaft, 104 first worm gear, 105 transmission gear, 106 transmission rack, 107 limit plate, 108 first worm, 109 driven bevel gear, 110 transmission shaft, 111 driving bevel gear, 112 connecting rod, 113 clamping block, 2 fixing mechanism, 201 supporting bin, 202 stabilizing component, 3 adjusting mechanism, 301 limit bin, 302 screw, 303 loop rod, 304 connecting block, 305 second worm, 306 second worm gear, 4 microfluidic chip body.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-3, a microfluidic device for cell embedding includes a bottom plate 1, a fixing mechanism 2 disposed on the top of the bottom plate 1, an adjusting mechanism 3 disposed on the outer side of the fixing mechanism 2, and a microfluidic chip body 4 disposed on the top of the fixing mechanism 2.

In this embodiment, the fixing mechanism 2 is used to fix and support the microfluidic chip body 4, and the adjusting mechanism 3 is used to adjust the height of the microfluidic chip body 4.

As shown in fig. 1-2, the fixing mechanism 2 includes a supporting chamber 201, two stabilizing assemblies 202 fixedly connected to the top of the supporting chamber 201 are fixedly connected to the inner top wall of the supporting chamber 201, each stabilizing assembly 202 includes a stabilizing telescopic rod and a stabilizing spring, the four stabilizing assemblies 202 are identical in size and are distributed in a rectangular shape, a driving mechanism is disposed inside the supporting chamber 201, the driving mechanism includes a fixing plate 101 fixedly connected to the front inner wall and the back inner wall of the supporting chamber 201, four mounting plates 102 are fixedly connected to the top of the fixing plate 101, the four mounting plates 102 are distributed in a rectangular shape, one side of each of the two mounting plates 102 on the back side close to the front mounting plate 102 is movably connected with a rotating shaft 103, one end of each rotating shaft 103 penetrates through and extends to the front side of the front mounting plate 102, a first worm wheel 104 located on the front side of the mounting plate 102 is fixedly connected to the outer side of each rotating shaft 103, a transmission gear 105 is fixedly connected to the outer side of each rotating shaft 103, the inner top wall of the supporting bin 201 is movably connected with two transmission racks 106 which are meshed with the transmission gear 105, the top of the fixing plate 101 is fixedly connected with four limiting plates 107, the insides of the two limiting plates 107 on the left side and the two limiting plates 107 on the right side are movably connected with first worms 108 which are meshed with the first worm wheel 104, one sides of the two first worms 108 which are opposite are fixedly connected with driven bevel gears 109, the front of the supporting bin 201 is movably connected with a transmission shaft 110 of which one end penetrates through and extends to the inside of the supporting bin 201, the outer side of the transmission shaft 110 is fixedly connected with driving bevel gears 111 which are meshed with the driven bevel gears 109, the tops of the two transmission racks 106 are fixedly connected with connecting rods 112 of which one end penetrates through and extends to the top of the supporting bin 201, a sliding block is fixedly connected between the transmission racks 106 and one side of the connecting rods 112 which are opposite, and a sliding rail which is connected with the sliding block is fixedly connected with the inner top wall of the supporting bin 201, the tops of the two connecting rods 112 are fixedly connected with clamping blocks 113.

It should be noted that the bottom of the supporting bin 201 is lacked, the top of the supporting bin 201 is provided with a rectangular through hole, the width of the rectangular through hole is matched with the width of the connecting rod 112, the sliding block and the sliding rail are arranged to limit the transmission rack 106 to only perform horizontal movement, the outer side of the transmission shaft 110 is fixedly connected with a knob located on the front side of the supporting bin 201, and one side of the two clamping blocks 113 opposite to each other is fixedly connected with a rubber protection pad.

In this embodiment, the fixing mechanism 2 is used to fix and support the microfluidic chip body 4, when the knob is rotated, the driving bevel gear 111 outside the transmission shaft 110 can drive the two driven bevel gears 109 to rotate simultaneously, the two first worms 108 can drive the first worm gears 104 engaged therewith to rotate simultaneously, the two rotation shafts 103 can drive the transmission gears 105 outside the two rotation shafts to rotate, the two transmission racks 106 can drive the clamping blocks 113 to move to one side opposite to or move to one side away from each other through the sliding blocks, the sliding rails and the connecting rod 112, so as to fix the left and right sides of the microfluidic chip, and meanwhile, the microfluidic chips with different sizes can be conveniently fixed.

As shown in fig. 1, the adjusting mechanism 3 includes two limiting bins 301, the top of the bottom plate 1 is movably connected with two screws 302, the outside of the two screws 302 is connected with a loop bar 303, the inside of the loop bar 303 is provided with a threaded through hole in threaded connection with the screws 302, the right side of the second worm 305 is fixedly connected with a turn button, the opposite side of the two loop bars 303 is fixedly connected with a connecting block 304 respectively connected with the left and right sides of the supporting bin 201, the left side inner wall of the left side limiting bin 301 is movably connected with a second worm 305, one end of the left side inner wall of the left side limiting bin 301 penetrates through and extends to the right side of the right side limiting bin 301, and the outside of the two screws 302 is fixedly connected with a second worm wheel 306 engaged with the second worm 305.

It should be noted that the tops of the two limiting bins 301 are missing, and the opposite sides of the two limiting bins are provided with limiting through holes, and the widths of the limiting through holes are matched with the width of the connecting block 304.

In this embodiment, adjustment mechanism 3 is used for adjusting the height of microfluid chip body 4, and when rotating the turn-button, second worm 305 alright drive its two second worm wheels 306 of meshing and rotate simultaneously, and two screw rods 302 alright rotate simultaneously and turn to the same, and two loop bars 303 alright drive through connecting block 304 and support storehouse 201 up-and-down motion to the microfluid chip body 4 up-and-down motion at storehouse 201 top is supported in the drive, and the staff of being more convenient for uses.

In summary, the microfluidic device for cell embedding can be used for clamping and fixing the microfluidic chip body 4 through the fixing mechanism 3, and can clamp microfluidic chip bodies 4 of different sizes, so that the practicability is enhanced.

In addition, the microfluidic device for embedding cells can be used for adjusting the height of the microfluidic chip body 4 through the adjusting mechanism 2, thereby being convenient for users to use.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A microfluidic device for cell embedding, comprising a base plate (1), characterized in that: the top of the bottom plate (1) is provided with a fixing mechanism (2), the outer side of the fixing mechanism (2) is provided with an adjusting mechanism (3), and the top of the fixing mechanism (2) is provided with a microfluid chip body (4);

the fixing mechanism (2) comprises a supporting bin (201), the inner top wall of the supporting bin (201) is fixedly connected with two stabilizing assemblies (202) which are fixedly connected with the top of the bottom plate (1), and a driving mechanism is arranged inside the supporting bin (201);

adjustment mechanism (3) are spacing storehouse (301) that quantity is two, the top swing joint of bottom plate (1) has screw rod (302) that quantity is two, two the equal threaded connection in outside of screw rod (302) has loop bar (303), two the equal fixedly connected with in one side that loop bar (303) is relative respectively with support storehouse (201) left and right sides fixed connection's connecting block (304).

2. The microfluidic device for cell encapsulation according to claim 1, wherein: actuating mechanism includes with the front inner wall that supports storehouse (201) and back inner wall fixed connection's fixed plate (101), the top fixedly connected with quantity of fixed plate (101) is mounting panel (102) of four, two in the back mounting panel (102) are close to the equal swing joint in one side of front mounting panel (102) one end and run through and extend to front mounting panel (102) positive pivot (103), two the equal fixedly connected with in the outside of pivot (103) is located mounting panel (102) positive first worm wheel (104), two the equal fixedly connected with drive gear (105) in the outside of pivot (103), the interior roof swing joint of support storehouse (201) has quantity to be two and with drive gear (105) meshed driving rack (106).

3. The microfluidic device for cell encapsulation according to claim 2, wherein: limiting plate (107) that the top fixedly connected with quantity of fixed plate (101) is four, two on the left side the equal swing joint in inside of two limiting plate (107) on limiting plate (107) and right side has first worm (108) with first worm wheel (104) meshing, two the driven awl tooth (109) of the equal fixedly connected with in one side that first worm (108) is relative, the positive swing joint that supports storehouse (201) has one end to run through and extend to transmission shaft (110) that supports storehouse (201) inside, the outside fixedly connected with of transmission shaft (110) and the initiative awl tooth (111) of driven awl tooth (109) meshing, two the equal fixedly connected with one end in top of driving rack (106) runs through and extends to connecting rod (112) that support storehouse (201) top, two the equal fixedly connected with clamp splice (113) in top of connecting rod (112).

4. The microfluidic device for cell encapsulation according to claim 1, wherein: the left side inner wall swing joint of spacing storehouse (301) has one end to run through and extend to second worm (305) on right side spacing storehouse (301) right side, two the equal fixedly connected with in outside of screw rod (302) and second worm wheel (306) of second worm (305) meshing.

5. The microfluidic device for cell encapsulation according to claim 2, wherein: the stabilizing assembly (202) comprises a stabilizing telescopic rod and a stabilizing spring, the four stabilizing assemblies (202) are the same in size and are distributed in a rectangular shape, and the four mounting plates (102) are distributed in a rectangular shape.

6. The microfluidic device for cell encapsulation according to claim 2, wherein: the sliding block is fixedly connected between one side, opposite to the transmission rack (106) and the connecting rod (112), of the supporting bin (201), and the sliding rail is fixedly connected with the inner top wall of the supporting bin and is in sliding connection with the sliding block.

7. The microfluidic device for cell encapsulation according to claim 4, wherein: the threaded through hole in threaded connection with the screw rod (302) is formed in the sleeve rod (303), and the right side of the second worm (305) is fixedly connected with a rotating button.