CN215388964U - Magnetic bead stirring device for nucleic acid extractor - Google Patents
Magnetic bead stirring device for nucleic acid extractor Download PDFInfo
- Publication number
- CN215388964U CN215388964U CN202121623155.2U CN202121623155U CN215388964U CN 215388964 U CN215388964 U CN 215388964U CN 202121623155 U CN202121623155 U CN 202121623155U CN 215388964 U CN215388964 U CN 215388964U
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- China
- Prior art keywords
- rod
- magnetic bead
- nucleic acid
- fixed
- supporting frame
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- Expired - Fee Related
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- 238000003756 stirring Methods 0.000 title claims abstract description 68
- 239000011324 bead Substances 0.000 title claims abstract description 50
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 34
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 34
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 34
- 238000004804 winding Methods 0.000 claims abstract description 5
- 230000007246 mechanism Effects 0.000 claims description 7
- 244000309464 bull Species 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 7
- 238000000605 extraction Methods 0.000 abstract description 5
- 239000000463 material Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
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Abstract
The utility model discloses a magnetic bead stirring device for a nucleic acid extraction instrument, which consists of a supporting frame, a magnetic bead fixing box and a stirring magnet; the magnetic bead fixing box is fixed on the upper side in the supporting frame, and a stirring magnet for uniformly mixing nucleic acid in the magnetic bead fixing box is arranged below the magnetic bead fixing box; the method comprises the following steps: the bearing is connected to the middle inside the supporting frame, and a motor for driving the threaded rod to rotate is mounted in the middle above the supporting frame; the clamping grooves are formed in the left side and the right side of the inner part of the supporting frame; the bracing piece, threaded connection be in the outside of threaded rod, the inside block of draw-in groove has the bracing piece to stirring magnet support. This magnetic bead agitating unit for nucleic acid extraction appearance installs gag lever post, lug and rope, promotes the gag lever post through the lug and rotates, and then makes rope winding pulling stirring magnet rotate, need not drive stirring magnet through the consumer and rotates, reduces the use of consumer, resources are saved.
Description
Technical Field
The utility model relates to the technical field of nucleic acid extractors, in particular to a magnetic bead stirring device for a nucleic acid extractor.
Background
The utility model relates to a nucleic acid extractor, in particular to a device for sampling a nucleic acid sample, which is mainly used in the medical industry, wherein a magnetic bead stirring device is required to be used in the process of researching the internal structure of nucleic acid, so that the internal magnetic beads are uniformly mixed, and the research on nucleic acid is prevented from being influenced by the magnetic beads, for example, the magnetic bead stirring device for the nucleic acid extractor disclosed as CN211445687U comprises a magnetic bead stirring device mounting plate, wherein a lead screw placing groove is formed in the middle of the magnetic bead stirring device mounting plate, and a vertical guide rail … … is arranged on one side of the magnetic bead stirring device mounting plate, so that the structure is simple, the operation is simple and convenient, the magnetic beads are uniformly mixed, the addition amount of the magnetic beads is consistent when the nucleic acid is extracted, the manpower and material resources are saved by automatic stirring, and the stirring efficiency is improved; however, the magnetic bead stirring device has certain problems in the use process:
1. in the process of moving and rotating the stirring magnet, the stirring magnet is driven to rotate by electric equipment, so that a large amount of electric power and cost are consumed, and the practicability is weaker;
2. this inside stirring magnet of magnetic bead agitating unit is carrying out the pivoted in-process, needs the rotational speed that realizes stirring magnet through the rotational speed that changes the consumer to adjust, and the phenomenon of load grow appears in the continuous regulation easily, and then leads to the phenomenon that the short circuit appears in the consumer, shortens the life of consumer.
Therefore, the magnetic bead stirring device for the nucleic acid extractor can well solve the problems.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a magnetic bead stirring device for a nucleic acid extraction instrument, which aims to solve the problems that the magnetic bead stirring device in the prior market needs a plurality of electric powers for stirring and needs to adjust the stirring speed of magnetic beads by adjusting the rotating speed of electric equipment in the background technology.
In order to achieve the purpose, the utility model provides the following technical scheme: a magnetic bead stirring device for a nucleic acid extractor comprises a supporting frame, a magnetic bead fixing box and a stirring magnet;
the magnetic bead fixing box is fixed on the upper side in the supporting frame, and a stirring magnet for uniformly mixing nucleic acid in the magnetic bead fixing box is arranged below the magnetic bead fixing box;
the method comprises the following steps:
the bearing is connected to the middle inside the supporting frame, and a motor for driving the threaded rod to rotate is mounted in the middle above the supporting frame;
the clamping grooves are formed in the left side and the right side of the inner part of the supporting frame;
the supporting rod is in threaded connection with the outer side of the threaded rod, and the supporting rod for supporting the stirring magnet is clamped in the clamping groove;
the fixing columns are fixed on the left side and the right side of the supporting frame;
the stirring magnet is connected to the middle of the upper part of the supporting rod through a bearing;
and the diameter changing mechanisms are arranged on the left side and the right side of the supporting rod.
Preferably, the support rod is provided with a rotating rod, a limiting rod and a guide groove;
the bearings are connected to the left side and the right side of the supporting rod, and a limiting rod for fixing the bump is fixed on the outer side of the rotating rod;
the guide way is seted up the left and right sides of bull stick, the guide way is the arc structure, makes stirring magnet rotate in the top of bracing piece, reduces the use of consumer.
Preferably, the diameter-changing mechanism comprises a guide rod, a turntable, a rope, a moving groove, a fixed rod and a limiting column;
the fixed rod is clamped inside the rotating rod, and a guide rod for winding a rope is fixed at the outer end of the fixed rod;
the bearing is connected to the outer side of the rotating rod, and a rope for pulling the stirring magnet to rotate is welded on the guide rod in the rotating rod;
the moving groove is formed around the inner part of the turntable;
the limiting column is fixed in the middle of the lower portion of the fixing rod, the limiting column which enables the fixing rod to move is clamped in the moving groove, the rotating speed of the stirring magnet is adjusted for the supporting rod, and the adjusting is carried out according to different conditions.
Preferably, the rotating rods on the left side and the right side of the supporting rod are opposite in rotating direction, and the rotating rods and the clamping grooves are symmetrically arranged about the central line of the supporting frame, so that the stirring magnet can rotate forwards and backwards to process the rope.
Preferably, the fixed rod moves through the moving groove in the rotating disc, the guide rod is of an arc-shaped structure, the guide rod is arranged at an equal angle relative to the center of the rotating rod, the rope is wound on the outer side of the guide rod, and the stirring magnet is pulled to rotate.
Preferably, the moving groove is of an arc structure, and the length of the moving groove is the moving distance of the fixing rod, so that the moving groove drives the guide rod to move.
Compared with the prior art, the utility model has the beneficial effects that: the magnetic bead stirring device for the nucleic acid extractor;
(1) the limiting rod, the lug and the rope are arranged, the lug pushes the limiting rod to rotate, the rope is further wound to pull the stirring magnet to rotate, the stirring magnet does not need to be driven to rotate by electric equipment, the use of the electric equipment is reduced, and resources are saved;
(2) the nucleic acid stirring device is provided with the guide rod, the rotary disc and the moving groove, the guide rod is moved through the rotation of the rotary disc and the moving groove, the diameter size formed by the guide rod is further adjusted, the rotating speed of the stirring magnet is adjusted, the nucleic acid stirring device is suitable for different nucleic acids, the adjustment of electric equipment is reduced, and the service life of the electric equipment is prolonged.
Drawings
FIG. 1 is a schematic view of the main sectional structure of the present invention;
FIG. 2 is a schematic cross-sectional view taken along line A-A of FIG. 1 according to the present invention;
FIG. 3 is an enlarged view of a portion a of FIG. 1 according to the present invention;
FIG. 4 is an enlarged view of the structure at b in FIG. 1 according to the present invention;
FIG. 5 is a schematic view of a top-down structure of the turntable according to the present invention.
In the figure: 1. a support frame; 2. a threaded rod; 3. a motor; 4. a magnetic bead fixing box; 5. a support bar; 501. a rotating rod; 502. a limiting rod; 503. a guide groove; 6. fixing a column; 7. a bump; 8. stirring a magnet; 9. a diameter-changing mechanism; 901. a guide bar; 902. a turntable; 903. a rope; 904. a moving groove; 905. fixing the rod; 906. a limiting column; 10. a clamping groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: a magnetic bead stirring device for a nucleic acid extractor comprises a supporting frame 1, a magnetic bead fixing box 4 and a stirring magnet 8;
a magnetic bead fixing box 4 fixed on the upper side in the supporting frame 1, wherein a stirring magnet 8 for uniformly mixing nucleic acid in the magnetic bead fixing box 4 is arranged below the magnetic bead fixing box 4;
magnetic bead agitating unit for nucleic acid extraction appearance includes:
the threaded rod 2 is connected to the middle inside the support frame 1 through a bearing, and the middle above the support frame 1 is provided with a motor 3 for driving the threaded rod 2 to rotate;
the clamping grooves 10 are formed in the left side and the right side of the inner part of the supporting frame 1;
the supporting rod 5 is in threaded connection with the outer side of the threaded rod 2, and the supporting rod 5 supporting the stirring magnet 8 is clamped in the clamping groove 10;
the fixing columns 6 are fixed on the left side and the right side of the supporting frame 1;
the stirring magnet 8 is connected to the middle of the upper part of the support rod 5 through a bearing;
and the diameter-changing mechanisms 9 are arranged on the left side and the right side of the support rod 5.
The support rod 5 is provided with a rotating rod 501, a limiting rod 502 and a guide groove 503; the rotating rod 501 is connected with the left side and the right side of the supporting rod 5 through bearings, and a limiting rod 502 for fixing the lug 7 is fixed on the outer side of the rotating rod 501; the guide grooves 503 are formed on the left side and the right side of the rotating rod 501, and the guide grooves 503 are of arc structures; the rotating directions of the rotating rods 501 on the left side and the right side of the supporting rod 5 are opposite, and the rotating rods 501 and the clamping grooves 10 are symmetrically arranged around the central line of the supporting frame 1;
referring to FIGS. 1 to 3, a nucleic acid is placed inside a magnetic bead fixing box 4 by a nucleic acid extraction machine, a power supply of a motor 3 is connected, the motor 3 drives a threaded rod 2 to synchronously rotate, the threaded rod 2 is in threaded connection with a support rod 5, the support rod 5 is clamped inside clamping grooves 10 on the left side and the right side, the threaded rod 2 rotates to drive the support rod 5 to move upwards, the support rod 5 drives rotating rods 501 on the left side and the right side to synchronously move upwards until the rotating rods 501 move inside a fixing column 6, a lug 7 is fixed inside the fixing column 6, the lug 502 is in an inclined structure, the rotating rods 501 move upwards to enable the lug 7 to enter the inside of a guide groove 503, the lug 7 enables the limiting rods 502 to rotate, the limiting rods 502 drive the rotating rods 501 and a guide rod 901 to synchronously rotate, the guide rod 901 rotates to enable a rope 903 to be wound, and further pulls a stirring magnet 8 to rotate above the support rod 5, stirring magnet 8 rotates when the rebound, and then the inside material of fixed box 4 of magnetic bead rotates, makes the material misce bene.
The diameter-changing mechanism 9 comprises a guide rod 901, a turntable 902, a rope 903, a moving groove 904, a fixed rod 905 and a limiting column 906; a fixed lever 905 engaged with the inside of the rotating lever 501, the fixed lever 905 having a guide bar 901 for winding a rope 903 fixed to an outer end thereof; a turntable 902, a bearing is connected to the outer side of the rotating rod 501, and a rope 903 for pulling the stirring magnet 8 to rotate is welded on a guide rod 901 in the rotating rod 501; a moving groove 904 provided around the inside of the turntable 902; a limiting column 906 fixed in the middle of the lower part of the fixed rod 905, wherein the limiting column 906 which enables the fixed rod 905 to move is clamped in the moving groove 904; the fixed rod 905 moves through a moving groove 904 in the turntable 902, the guide rod 901 is in an arc structure, and the guide rod 901 is arranged at an equal angle relative to the center of the rotating rod 501; the moving groove 904 is of an arc structure, and the length of the moving groove 904 is the moving distance of the fixed rod 905;
with reference to fig. 1-2 and fig. 4-5, when the stirring speed is to be adjusted, the rotating disc 902 is rotated by hand, and then the rotating disc 902 rotates outside the rotating rod 501, the rotating rod 501 drives the moving groove 904 to rotate synchronously, because the fixed rod 905 is clamped inside the rotating rod 501, the moving groove 904 rotates to make the spacing column 906 move up and down, and then the fixed rod 905 moves outwards, and the fixed rod 905 drives the guide rod 901 to move synchronously, because the guide rod 901 is of an arc-shaped structure, and then the outer diameter of the guide rods 901 around is adjusted, and then the rotating speed of the stirring magnet 8 is adjusted, and the rotating speed of the electric equipment for adjusting the inside is not required.
The working principle is as follows: when the magnetic bead stirring device for the nucleic acid extractor is used, with reference to fig. 1 to 5, the limiting column 906 is moved by the rotation of the moving groove 904, the guide rod 901 is moved outward to adjust the diameter of the guide rod 901, the axial diameter difference between the guide rod 901 and the stirring magnet 8 is changed, the rotation speed of the stirring magnet 8 is adjusted, the rotating rod 501 is rotated while being moved by the pushing of the bump 7, and the stirring magnet 8 is rotated by the winding of the rope 903, so that the use of electric equipment is reduced.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the utility model can be made, and equivalents and modifications of some features of the utility model can be made without departing from the spirit and scope of the utility model.
Claims (6)
1. A magnetic bead stirring device for a nucleic acid extractor comprises a supporting frame, a magnetic bead fixing box and a stirring magnet;
the magnetic bead fixing box is fixed on the upper side in the supporting frame, and a stirring magnet for uniformly mixing nucleic acid in the magnetic bead fixing box is arranged below the magnetic bead fixing box;
it is characterized by comprising:
the bearing is connected to the middle inside the supporting frame, and a motor for driving the threaded rod to rotate is mounted in the middle above the supporting frame;
the clamping grooves are formed in the left side and the right side of the inner part of the supporting frame;
the supporting rod is in threaded connection with the outer side of the threaded rod, and the supporting rod for supporting the stirring magnet is clamped in the clamping groove;
the fixing columns are fixed on the left side and the right side of the supporting frame;
the stirring magnet is connected to the middle of the upper part of the supporting rod through a bearing;
and the diameter changing mechanisms are arranged on the left side and the right side of the supporting rod.
2. The magnetic bead stirring device for the nucleic acid extractor as claimed in claim 1, wherein the support rod is provided with a rotating rod, a limiting rod and a guide groove;
the bearings are connected to the left side and the right side of the supporting rod, and a limiting rod for fixing the bump is fixed on the outer side of the rotating rod;
the guide way is seted up the left and right sides of bull stick, the guide way is the arc structure.
3. The magnetic bead stirring device for the nucleic acid extractor as claimed in claim 2, wherein the diameter-changing mechanism comprises a guide rod, a turntable, a rope, a moving groove, a fixing rod and a limiting column;
the fixed rod is clamped inside the rotating rod, and a guide rod for winding a rope is fixed at the outer end of the fixed rod;
the bearing is connected to the outer side of the rotating rod, and a rope for pulling the stirring magnet to rotate is welded on the guide rod in the rotating rod;
the moving groove is formed around the inner part of the turntable;
and the limiting column is fixed in the middle of the lower part of the fixed rod, and the limiting column for enabling the fixed rod to move is clamped in the moving groove.
4. The magnetic bead stirring device for the nucleic acid extractor of claim 2, wherein the rotation directions of the rotation rods on the left side and the right side of the support rod are opposite, and the rotation rods and the clamping grooves are symmetrically arranged about the center line of the support frame.
5. The magnetic bead stirring apparatus for a nucleic acid extractor of claim 3, wherein the fixing rod moves through a moving groove inside the turntable, the guide rod has an arc-shaped structure, and the guide rod is disposed at an equal angle with respect to the center of the rotation rod.
6. A magnetic bead stirring device for a nucleic acid extractor according to claim 3, wherein: the movable groove is of an arc-shaped structure, and the length of the movable groove is the moving distance of the fixed rod.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121623155.2U CN215388964U (en) | 2021-07-16 | 2021-07-16 | Magnetic bead stirring device for nucleic acid extractor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121623155.2U CN215388964U (en) | 2021-07-16 | 2021-07-16 | Magnetic bead stirring device for nucleic acid extractor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215388964U true CN215388964U (en) | 2022-01-04 |
Family
ID=79650039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121623155.2U Expired - Fee Related CN215388964U (en) | 2021-07-16 | 2021-07-16 | Magnetic bead stirring device for nucleic acid extractor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN215388964U (en) |
-
2021
- 2021-07-16 CN CN202121623155.2U patent/CN215388964U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20220104 |