CN215388793U - Solid-liquid two-phase gel stirring and filling system - Google Patents

Solid-liquid two-phase gel stirring and filling system Download PDF

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Publication number
CN215388793U
CN215388793U CN202121752561.9U CN202121752561U CN215388793U CN 215388793 U CN215388793 U CN 215388793U CN 202121752561 U CN202121752561 U CN 202121752561U CN 215388793 U CN215388793 U CN 215388793U
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gel
filling
stirring
liquid
solid
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CN202121752561.9U
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蔡天赐
王立山
公兵丽
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Shinva Medical Instrument Co Ltd
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Shinva Medical Instrument Co Ltd
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Abstract

The utility model discloses a solid-liquid two-phase gel stirring and filling system, wherein gel is stored in a gel container, the lower part of a stirring paddle extends into the gel container, and a driving motor drives the stirring paddle to rotate to stir gel in the gel container, so that the gel in the gel container is fully and uniformly mixed. The positioning needle seat is used for clamping the filling needle module, the lifting driver can drive the positioning needle seat to move up and down, and each filling needle of the filling needle module is corresponding to a micro-column into which a micro-column gel reagent card is inserted; and starting the pumping device, driving the gel in the gel conveying pipeline to move by the pumping device, respectively conveying the gel to the filling needle modules from the gel container through the gel conveying pipeline, and discharging the gel into the micro-column gel reagent card from each filling needle to finish the filling process. The stirring, the pumping and the filling of the gel are mutually matched in the process, the filling of the gel is automatically completed, the efficiency is improved, and the gel can be prevented from being scattered in the transferring process.

Description

Solid-liquid two-phase gel stirring and filling system
Technical Field
The utility model relates to the technical field of gel production, and further relates to a solid-liquid two-phase gel stirring and filling system.
Background
The reagent card is packed with dextran gel containing or not containing antibody, and the detection is carried out by utilizing the characteristic that the gaps among gels only allow free red blood cells to pass through.
In order to keep the uniformity of the gel and prevent the gel from precipitating and coagulating, shaking tables and other modes are usually adopted at present, and the uniformity degree is not ideal; in the prior art, a multi-step filling method of separately filling glue solution is adopted in the production process of the micro-column gel reagent card, and the next process can be continued only after one process is filled, so that the efficiency is low, and when the gel is filled at the bottom of the reagent card, the phenomena of little liquid outlet, no liquid outlet and solidification, precipitation and condensation of the liquid in a filling needle head can occur; some adopt to increase the glue solution collection box, pour the gel into the collection box at non-filling time, but the gel volatilizes very easily, is polluted, produces extravagantly and increases manufacturing cost. Some adopt and tell filling mode before inhaling, just pump the glue solution to filling needle half section down through the filling pump and then fill, though can solve like this and go out liquid less, do not go out liquid, glue solution deposit and condense, but filling needle needs straight line or rotatory removal sample refilling, and the filling speed is slow hardly satisfies enterprise's productivity demand.
For those skilled in the art, how to automatically and efficiently realize the stirring, conveying and filling of the gel is a technical problem to be solved at present.
SUMMERY OF THE UTILITY MODEL
The utility model provides a solid-liquid two-phase gel stirring and filling system which can automatically complete stirring, conveying and filling and improve the production efficiency, and the specific scheme is as follows:
a solid-liquid two-phase gel stirring and filling system comprises a stirring device, a pumping device and a filling device;
the stirring device comprises a gel container, a stirring paddle and a driving motor, gel is stored in the gel container, the lower part of the stirring paddle extends into the gel container, and the driving motor drives the stirring paddle to rotate so as to stir the gel in the gel container;
the filling device comprises a lifting driver and a positioning needle seat, wherein the positioning needle seat is used for clamping the filling needle module, and the lifting driver can drive the positioning needle seat to move up and down so as to enable the filling needle to be aligned to the microcolumn into which the microcolumn gel reagent card is inserted;
each filling needle on the filling needle module is connected to the gel container through a rubber conveying pipeline, and the pumping device is arranged on the rubber conveying pipeline and used for pumping the rubber liquid in the gel container to the filling needle module.
Optionally, the gel container with the stirring rake sets up two sets ofly at least, the stirring rake with through belt, chain or gear drive between the driving motor, the stirring rake can drive next grade the stirring rake rotates.
Optionally, the stirring paddle comprises a transmission shaft, a hollow shaft and a driven pulley, the transmission shaft is inserted into an inner cavity of the hollow shaft, and the driven pulley is circumferentially fixed to the hollow shaft;
the transmission shaft can move axially relative to the hollow shaft, and the lower part of the transmission shaft is provided with a paddle.
Optionally, the hollow shaft is mounted on a bearing block by at least two rotational bearings.
Optionally, the transmission shaft and the hollow shaft are connected through a flat key or a spline; the hollow shaft is connected with the driven belt wheel through a flat key or a spline;
the transmission shaft is detachably and fixedly provided with a fixed limiting ring, and the lower surface of the fixed limiting ring is in contact with the bearing seat to realize axial limiting.
Optionally, the driven pulley or the hollow shaft is movably mounted with a ball plunger in a radial direction, the ball plunger includes a movable inner core and a fixed shell, the fixed shell is fixed to the hollow shaft, the movable inner core can move in the radial direction, an elastic member is disposed between the movable inner core and the fixed shell, and the movable inner core is subjected to an elastic force in a direction towards the transmission shaft and can be pushed against a positioning groove disposed on the transmission shaft to achieve axial positioning.
Optionally, the propeller shaft comprises an upper section and a lower section that are clamped to each other, and the paddle is disposed at the lower section.
Optionally, at least two groups of the blades are arranged along the axial direction, and each group of the blades has an included angle in the circumferential direction.
Optionally, the filling device comprises a guide plate slidably fitted on the positioning needle seat, and a filling needle on the filling needle module can penetrate through the guide plate; the deflector downward protrusion sets up the location axle sleeve, the little post on little post gel reagent card can be inserted to the location axle sleeve, realizes circumferential direction and adjusts.
Optionally, at least two guide shafts are vertically arranged on the guide plate, and the guide shafts are inserted into the positioning needle seats in a guiding manner.
Optionally, a return spring is arranged between the guide shaft and the positioning needle seat, and the return spring can apply downward elastic force to the guide shaft.
Optionally, a hose arranging block is arranged at the upper part of the positioning needle seat, and each filling needle of the filling needle module corresponds to one through hole in the hose arranging block for the rubber delivery pipeline to pass through.
Optionally, identification marks are engraved or etched on the surface of the hose tidying block, and each identification mark correspondingly distinguishes the glue conveying pipeline connected with one filling needle.
Optionally, the pumping device comprises a filling motor, a filling pump head and a grating sensor, wherein the grating sensor is used for detecting the number of rotation turns of the filling motor.
Optionally, the gel container is provided with a tank cover, an automatic liquid supplementing system is connected to the tank cover, and gel is supplemented by matching with a liquid level sensor in the gel container.
Optionally, the filling motor is a variable frequency motor, and the rotation speed of the filling motor is adaptively adjusted according to the conditions of the gel filling component, the viscosity and the residual amount of the glue solution.
Optionally, a liquid distributor is arranged at a liquid outlet at the bottom of the gel container, and the liquid distributor can convey gel to at least two groups of filling devices.
Optionally, the gel container is a borosilicate container; the liquid separator is a 304 or 306L stainless steel joint; the inner surface of the gel container, the outer surface of the stirring paddle and the inner surface of the liquid distributor are in smooth transition without dead angles.
The utility model provides a solid-liquid two-phase gel stirring and filling system, wherein gel is stored in a gel container, the lower part of a stirring paddle extends into the gel container, and a driving motor drives the stirring paddle to rotate to stir gel in the gel container, so that the gel in the gel container is fully and uniformly mixed. The positioning needle seat is used for clamping the filling needle module, the lifting driver can drive the positioning needle seat to move up and down, and each filling needle of the filling needle module is corresponding to a micro-column into which a micro-column gel reagent card is inserted; and starting the pumping device, driving the gel in the gel conveying pipeline to move by the pumping device, respectively conveying the gel to the filling needle modules from the gel container through the gel conveying pipeline, and discharging the gel into the micro-column gel reagent card from each filling needle to finish the filling process. The stirring, the pumping and the filling of the gel are mutually matched in the process, the filling of the gel is automatically completed, the efficiency is improved, and the gel can be prevented from being scattered in the transferring process.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic diagram of the overall structure of a solid-liquid two-phase gel stirring and filling system provided by the utility model;
FIG. 2 is a schematic structural view of a stirring device;
FIG. 3 is a schematic structural view of the filling apparatus;
FIG. 4 is an enlarged partial view of the dashed box of FIG. 2;
FIG. 5 is a cross-sectional view taken along line A-A of FIG. 1;
figure 6 is a cross-sectional view of the upper section of the drive shaft,
FIG. 7 is a partial longitudinal sectional view taken along the X-X direction in FIG. 6;
FIG. 8 is a longitudinal sectional view taken in the Y-Y direction of FIG. 6;
FIG. 9 is a schematic view of the detent and ball plunger of FIG. 8 shown in phantom;
FIG. 10 is a view showing the structure of the lower section of the drive shaft;
fig. 11 is a cross-sectional view taken at B-B in fig. 1.
The figure includes:
the device comprises a stirring device 1, a gel container 11, a liquid distributor 111, a stirring paddle 12, a transmission shaft 121, an avoidance groove 1211, a clamping column 1212, a sleeve 1213, a hollow shaft 122, a driven pulley 123, a paddle 124, a fixed limit ring 125, a ball plunger 126, a driving motor 13, a pumping device 2, a filling motor 21, a filling pump head 22, a grating sensor 23, a filling device 3, a lifting driver 31, a positioning needle seat 32, a filling needle module 33, a guide plate 34, a positioning shaft sleeve 341, a guide shaft 342, a return spring 343, a hose arrangement block 35, a hose conveying pipeline 4, a bearing seat 5, a rotary bearing 51 and an automatic liquid supplementing system 6.
Detailed Description
The core of the utility model is to provide a solid-liquid two-phase gel stirring and filling system which can automatically complete stirring, conveying and filling and improve the production efficiency.
In order to make those skilled in the art better understand the technical solution of the present invention, the following will describe the solid-liquid two-phase gel stirring and filling system of the present invention in detail with reference to the accompanying drawings and specific embodiments.
The solid-liquid two-phase gel stirring and filling system comprises a stirring device 1, a pumping device 2, a filling device 3 and the like, and is used for stirring, conveying and filling gel in multiple steps. Fig. 1 is a schematic diagram of the overall structure of a solid-liquid two-phase gel stirring and filling system provided by the utility model.
FIG. 2 is a schematic structural view of the stirring apparatus 1; the stirring device 1 is used for stirring gel, and comprises a gel container 11, a stirring paddle 12 and a driving motor 13, wherein gel is stored in the gel container 11, and the gel container is of a tank structure with an opening at the top, so that a tank cover can be correspondingly assembled, and pollution is reduced. The gel is stored in the gel container 11, and the gel is discharged for subsequent transfer transportation after being stirred and mixed uniformly in the gel container 11.
The stirring paddle 12 is of a mixing and stirring structure, and the lower part of the stirring paddle 12 extends into the gel container 11 and is directly contacted with the gel; driving motor 13 is connected on the upper portion of stirring rake 12, drives stirring rake 12 and rotates, stirs the gel in gel container 11 through the mode of constantly circulating the transportation, makes the granule in the gel keep evenly distributed, mixes the gel for traditional mode through rocking, can greatly promote the degree of consistency and the efficiency of mixing.
Fig. 3 is a schematic structural diagram of the filling device 3; the filling device 3 comprises a lifting driver 31 and a positioning needle seat 32, wherein the lifting driver 31 can adopt the forms of an electric cylinder, a hydraulic cylinder, a screw rod and the like, and comprises a fixed part and a movable part, the fixed part is arranged on the rack and is kept fixed, and the movable part can move up and down relative to the fixed part. The needle positioning seat 32 is mounted on the movable part and can move synchronously with the movable part.
The positioning needle seat 32 is used for clamping the filling needle module 33, the filling needle module 33 is detachably mounted on the positioning needle seat 32, a plurality of filling needles are centrally mounted on each filling needle module 33, the filling needle module 33 shown in fig. 1 is provided with six filling needles in total, the filling needle module can be applied to six micro-column gel reagent cards, if eight micro-column gel reagent cards are provided, the eight filling needles can be correspondingly arranged, and the size of the positioning needle seat 32 is correspondingly changed.
The lifting driver 31 can drive the positioning needle seat 32 and the filling needle module 33 to move up and down, so that the filling needle moves downwards to be correspondingly inserted into the microcolumn of the microcolumn gel reagent card, the filling process can be started after the filling needle is inserted in place, and the filling needle moves upwards to be moved out of the microcolumn gel reagent card after the filling is finished.
Each filling needle on the filling needle module 33 is connected to the gel container 11 through the gel conveying pipeline 4, and the gel in the gel container 11 conveys the gel liquid to each filling needle on the filling needle module 33 through the gel conveying pipeline 4; the pumping device 2 is arranged on the glue conveying pipeline 4, provides power for conveying the glue solution, and pumps the glue solution in the gel container 11 to the needle filling module 33.
When the system works, the driving motor 13 in the stirring device 1 drives the stirring paddle 12 to rotate, and the stirring paddle 12 continuously stirs the gel in the gel container 11, so that the gel is kept in a uniformly mixed state; when filling is needed, the micro-column gel reagent card is placed below the filling needle module 33, the process can be independently completed by other equipment, after the filling is completed, the lifting driver 31 drives the positioning needle seat 32 and the filling needle module 33 to move downwards, each filling needle on the filling needle module 33 respectively extends into the micro-column gel reagent card, the pumping device 2 is started, and gel is conveyed into the micro-column gel reagent card through the gel conveying pipeline 4; after filling, the lifting driver 31 drives the positioning needle seat 32 and the filling needle module 33 to move upwards, each filling needle moves out of the micro-column gel reagent card, the filled micro-column gel reagent card can be taken out, and the next micro-column gel reagent card is placed to repeat the process.
The solid-liquid two-phase gel stirring and filling system can realize the processes of stirring, pumping, filling and the like of the gel, can realize automatic filling only by continuously placing the micro-column gel reagent card, and improves the efficiency; in this process, the position of the filling needle module 33 does not need to be changed by large translation, and the gel can be prevented from dripping from the filling needle.
On the basis of the scheme, at least two groups of stirring devices 1 are arranged, each group of stirring devices 1 has the same structure, and a plurality of gel containers 11 are arranged for stirring, so that batch production is realized.
Each gel container 11 needs to be provided with a group of stirring paddles 12 respectively, and two transmission modes to the stirring paddles 12 are provided, wherein one mode is directly driven, and the other mode is indirectly driven; the direct drive is that the stirring paddle 12 and the driving motor 13 are driven by a belt, a chain or a gear; the indirect drive is that the stirring paddle 12 drives the next-stage stirring paddle 12 to rotate through the transmission of a belt, a chain or a gear.
For two or more groups of gel containers 11 and stirring paddles 12, the gel containers 11 are at least correspondingly provided with one group of stirring paddles 12, the direct drive and the indirect drive can exist simultaneously, one or more stirring paddles 12 are directly driven by a driving motor 13, and other stirring paddles 12 are mutually driven.
Preferably, the stirring paddle 12 provided by the present invention comprises a transmission shaft 121, a hollow shaft 122 and a driven pulley 123, which are shown in fig. 4 and are partially enlarged in a dashed box in fig. 2; the transmission structure shown in the figure is a belt, a driving pulley is provided on an output shaft of the driving motor 13, the driving pulley transmits power to the driven pulley 123 through the belt, and the driven pulley 123 further drives the other driven pulley 123 to rotate. The hollow shaft 122 is a cylindrical structure with two through ends, the transmission shaft 121 is inserted into an inner cavity of the hollow shaft 122, the transmission shaft 121 can move axially relative to the hollow shaft 122, the paddle 124 is arranged at the lower part of the transmission shaft 121, and the transmission shaft 121 can move in the up-and-down direction shown in the figure.
The driven pulley 123 is circumferentially fixed to the hollow shaft 122, and the driven pulley 123 and the hollow shaft 122 are kept rotating synchronously, and the hollow shaft 122 and the transmission shaft 121 are kept rotating synchronously.
The bearing seat 5 is fixed on the frame and keeps fixed, two rotating bearings 51 are installed on the bearing seat 5, the hollow shaft 122 is installed on the bearing seat 5 through at least two rotating bearings 51, the hollow shaft 122 is fixedly assembled on the inner ring of the rotating bearing 51, the outer ring of the rotating bearing 51 is fixed on the bearing seat 5, and friction during rotation is reduced through the bearings.
Specifically, the transmission shaft 121 and the hollow shaft 122 of the present invention are connected by a flat key or a spline; the hollow shaft 122 and the driven pulley 123 are connected through a flat key or a spline; fig. 5 is a sectional view taken along line a-a of fig. 1, in which the driving shaft 121 and the hollow shaft 122 are circumferentially relatively fixed by a flat key a, and the hollow shaft 122 and the driven pulley 123 are circumferentially relatively fixed by a flat key.
Because the transmission shaft 121 can move axially relative to the hollow shaft 122, the transmission shaft 121 needs to be kept at a specific height during normal operation, therefore, a fixed limiting ring 125 is detachably and fixedly arranged on the transmission shaft 121, and the limiting ring 125 can be arranged on the periphery of the transmission shaft 121 in a surrounding manner and protrudes out of the outer surface of the transmission shaft 121 to form an annular step; the lower surface of the fixed limit ring 125 contacts with the top end of the bearing seat 5 to realize axial limit. The fixed limiting ring 125 can be detached from the transmission shaft 121 independently, the axial position of the fixed limiting ring relative to the transmission shaft 121 can be changed, the fixed limiting ring 125 is located at different positions, the transmission shaft 121 can be fixed at different heights, and the fixed limiting ring can be matched with gel containers 11 of different sizes and specifications for use, so that the adjustment is convenient.
The fixed limit ring 125 may be a ring with a notch, or two semicircles may be formed by assembling oppositely, and a ring is fixed by a bolt fastening manner and is firmly fixed on the transmission shaft 121.
The driven pulley 123 or the hollow shaft 122 is provided with a ball plunger 126 in a radial direction, as shown in fig. 5, which shows a structure in which the ball plunger 126 is provided to the driven pulley 123; the ball plunger 126 comprises a movable inner core and a fixed outer shell, the fixed outer shell is a cylindrical through shell structure, the movable inner core is inserted in the fixed outer shell, and the movable inner core can slide relative to the fixed outer shell along the length direction, namely, can move along the radial direction of the driven pulley 123; the fixed housing is fixedly mounted on the hollow shaft 122, an elastic member, typically a coil spring, is disposed between the fixed housing and the movable inner core, the movable inner core is subjected to an elastic force of the elastic member, and the movable inner core of the ball plunger 126 is subjected to an elastic force toward the axis, and can be pushed against a positioning groove formed in the transmission shaft 121 to achieve axial positioning. Preferably, an external thread is provided on the outside of the fixed housing, an internal thread is provided in the mounting hole of the driven pulley 123, the fixed housing is screw-fitted to the driven pulley 123, a prismatic screwing structure is provided at the end of the fixed housing extending outward, and the fixed housing is screwed by a tool such as a wrench.
The inner end of the movable inner core can be propped against the transmission shaft 121, the outer end of the movable inner core can extend out of the fixed shell, and the outer end of the movable inner core is provided with a pull ring or a handle so as to apply acting force to the movable inner core outwards; under the condition of no external force, the inner end of the movable inner core is propped against the transmission shaft 121 due to the elastic force, and the movable inner core and the transmission shaft 121 can be separated from each other when being pulled outwards.
FIG. 6 is a cross-sectional view of the upper section of the drive shaft 121, FIG. 7 is a partial longitudinal sectional view taken in the direction X-X in FIG. 6, and FIG. 8 is a longitudinal sectional view taken in the direction Y-Y in FIG. 6; in the drawing, i represents a key groove formed in the side wall of the transmission shaft 121, ii represents a plurality of positioning grooves formed in the side wall of the transmission shaft 121, and fig. 9 is a schematic view of the positioning grooves and the ball plunger 126 in the dotted frame portion in fig. 8.
Through the arrangement of the ball plunger 126, when the transmission shaft 121 is pulled up to a certain height, the movable inner core of the ball plunger 126 is clamped into the positioning groove at the corresponding position on the outer surface of the transmission shaft 121, so that the transmission shaft 121 is kept at a higher position, and the gel container 11 below the transmission shaft is cleaned conveniently. After the operation is finished, the movable inner core of the ball plunger 126 is pulled outwards to loosen the transmission shaft 121, or the transmission shaft 121 is directly pressed downwards to release the locking of the movable inner core, so that the transmission shaft 121 can move downwards to reset and extend into the gel container 11.
In order to facilitate the operation, a ball head structure can be expanded at the top end of the transmission shaft 121 to facilitate the holding by hands.
The transmission shaft 121 comprises an upper section and a lower section which are clamped with each other, the paddle 124 is arranged on the lower section, and the upper section is not provided with the paddle; fig. 10 is a structural view of a lower section of the transmission shaft 121, and the structure of the interconnecting portion between the upper section and the lower section is the same; the mutual connection parts of the upper section and the lower section respectively comprise an avoiding groove 1211 and a clamping column 1212, the clamping column 1212 of the upper section is clamped into the avoiding groove 1211 of the lower section, the clamping column 1212 of the lower section is clamped into the avoiding groove 1211 of the upper section, and a complete cylindrical structure is formed after mutual clamping. After the upper section and the lower section are connected with each other, the upper section and the lower section cannot move relatively along the axial direction; a sleeve 1213 is sleeved on the periphery of the formed cylinder to prevent the upper and lower sections from moving relatively in the radial direction, so that the upper and lower sections are fixed relatively.
At least two groups of blades 124 are arranged along the axial direction, in the structure shown in fig. 10, an upper group of blades 124, a middle group of blades and a lower group of blades 124 are arranged, and included angles between the three groups of blades in the radial direction are zero degrees; in the present invention, it is preferable that the included angles of the groups of blades 124 are distributed uniformly in the circumferential direction, and these specific embodiments are all included in the scope of the present invention.
As shown in fig. 3, the filling device 3 includes a guide plate 34 slidably mounted on the positioning needle holder 32, and the filling needle on the filling needle module 33 can extend downward through the guide plate 34; the lower surface of the guide plate 34 is provided with a positioning shaft sleeve 341 protruding downwards, and the positioning shaft sleeve 341 can be inserted into the microcolumn on the microcolumn gel reagent card to realize circumferential adjustment. The lower end of the positioning sleeve 341 is slightly smaller, and the smaller end is set to be a round angle, so that the positioning sleeve can be inserted accurately.
At least two positioning sleeves 341 are provided, and each positioning sleeve 341 surrounds one filling needle, and the filling needle is located at the central axis of the positioning sleeve 341. The shape of the outer surface of the positioning shaft sleeve 341 is similar to the shape of the inner surface of the micro-column on the micro-column gel reagent card, and the lower end of the positioning shaft sleeve 341 can extend into the micro-column; in the process of descending, if the position of the microcolumn gel reagent card is not completely aligned with the filling needle, the positioning shaft sleeve 341 contacts the inner wall of the microcolumn gel reagent card, corrects the position of the microcolumn gel reagent card, and is aligned with the center of each microcolumn when the filling needle is completely inserted.
Furthermore, the utility model is provided with at least two guide shafts 342 along the vertical direction on the guide plate 34, and the guide shafts 342 are inserted into the positioning needle seat 32 in a guiding way. As shown in fig. 3, the guide shafts 342 are located at both ends of the guide plate 34, vertically inserted into the guide grooves of the retainer pins 32, and vertically movable along the guide grooves.
A return spring 343 is arranged between the guide shaft 342 and the positioning needle seat 32, and the return spring 343 can apply downward elastic force to the guide shaft 342; referring to fig. 3, the return spring 343 is a coil spring and is sleeved on the top periphery of the guide shaft 342, the lower end of the return spring 343 abuts against a stopper protruding outside the guide shaft 342, the upper end of the return spring 343 contacts with the retainer pin holder 32, and the return spring 343 generates downward elastic force on the guide shaft 342 to keep the guide shaft 342 at a low position.
When the lifting driver 31 drives the locating needle seat 32 to descend, the guide plate 34 descends together, the guide plate 34 is firstly blocked by the micro-column gel reagent card and cannot descend, the locating needle seat 32 continues to descend, the return spring 343 is compressed at the moment, the length of the filling needle exposed from the locating shaft sleeve 341 is increased, and the filling needle stops descending when approaching the bottom end of the micro-column and starts to fill; and after completion, the material rises reversely.
Preferably, the hose arranging block 35 is arranged at the upper part of the positioning needle seat 32, each filling needle of the filling needle module 33 corresponds to one through hole on the hose arranging block 35 for the glue conveying pipeline 4 to pass through, and each glue conveying pipeline 4 is led out neatly through each through hole on the hose arranging block 35 so as to prevent mutual winding.
Preferably, according to the utility model, identification marks are engraved or etched on the surface of the hose sorting block 35, each identification mark correspondingly distinguishes the rubber conveying pipeline 4 connected with one filling needle, and the identification marks can be in the form of 1, 2, 3, 4 … or marks such as a, b, c, d …, and the like, so that the identification and the quick distinguishing of the rubber conveying pipelines 4 are facilitated, and the confusion is prevented.
On the basis of any one of the technical schemes and the mutual combination thereof, the pumping device 2 comprises a filling motor 21, a filling pump head 22 and a grating sensor 23, wherein the filling motor 21 drives the filling pump head 22 to work, the filling pump head 22 can realize ul-level precise filling of solid-liquid two-phase micro-column gel, the principle is a rotary plunger pump principle, the gel is contacted with the gel, the gel is sucked and then discharged, and the gel needs to be cleaned before and after the filling. The grating sensor 23 is used for detecting the rotation number of the filling motor 21 and controlling the pumping amount according to the rotation number. The solid-liquid two-phase gel stirring and filling system can realize microcolumn filling of gel reagent cards, and can also realize the pumping back of glue solution under certain conditions, namely, a filling motor 21 rotates reversely to drive a filling pump head 22 to act, and an optical grating sensor 23 feeds back the rotation angle displacement of the motor.
Preferably, the solid-liquid two-phase gel stirring and filling system can realize the online or offline cleaning function: after the glue solution is filled, purified water (distilled water) is added into the gel container 11, the filling motor 21 drives the filling pump head 22 to rotate forward and backward, and flushing (cleaning) and backwashing (backwashing) of the filling needle, the rubber delivery pipeline 4, the filling pump head 22, the liquid distributor 111, the gel container 11 and the like can be realized.
As shown in fig. 1, the gel container 11 is provided with a can cover to prevent external impurities from falling, and a handle may be provided on an upper surface of the can cover to open the can cover; connect automatic fluid infusion system 6 on the cover, only hardly observe at any time by people's naked eye to the monitoring of glue solution surplus in the container, level sensor supplyes gel in the cooperation gel container 11, level sensor and automatic fluid infusion system 6 are controlled by PLC, level sensor detects glue solution surplus signal feedback and transmits PLC, liquid level in gel container 11 is less than the minimum, start automatic fluid infusion system 6 and add supplementary gel in to gel container 11, liquid level in the gel container 11 reaches the highest liquid level, control automatic fluid infusion system 6 and stop supplyes gel.
The filling motor 21 is a variable frequency motor, and the rotating speed of the filling motor is adaptively adjusted according to the conditions of filling gel components, viscosity and glue solution residual amount; when the glue solution in the glass tank container is not excessive or is about to be exhausted, air is easily mixed to form bubbles, so that the filling motor 21 is a speed-adjustable motor, and the stirring speed can be adaptively adjusted according to the conditions of different filling gel components, different viscosities and the glue solution residual amount in the container, thereby realizing optimal control.
In combination with the above description, the present invention has two liquid level detection modes, one is to directly detect the liquid level of the gel container 11 by the liquid level sensor, and the other is to calculate the residual amount of the glue solution in the container according to the pumping frequency of the filling pump head 22. The PLC adjusts the rotation speed of the filling motor 21 according to the liquid level in the gel container 11.
The second method is characterized in that the volume of the container is fixed, the largest scale mark line is filled before filling each time, and the volume of the glue solution extracted by the filling pump each time is fixed, so that the residual quantity of the glue solution in the container can be calculated and transmitted to the PLC in a feedback manner according to the pumping and filling times of the filling pump, and the PLC sends a signal to control and adjust the rotating speed of the stirring motor.
Furthermore, the liquid outlet at the bottom of the gel container 11 is provided with a liquid distributor 111, as shown in fig. 11, which is a cross-sectional view taken along line B-B in fig. 1, showing the structure of the liquid distributor 111; the dispenser 111 can deliver gel to at least two groups of filling devices 3, a feeding port in the center of the dispenser 111 is connected to a discharging port of the gel container 11, two discharging ports are arranged in fig. 11 and respectively output gel along the direction indicated by an arrow, each discharging port is connected to one group of filling devices 3 through a glue delivery pipeline 4, each group of filling devices 3 is powered by a set of pumping devices 2, and one gel container 11 supplies gel to multiple groups of filling devices 3.
The gel container 11 is a borosilicate container; the liquid distributor 111 is a 304 or 306L stainless steel joint; the inner surface of the gel container 11, the outer surface of the stirring paddle 12 and the inner surface of the liquid distributor 111 are all in a smooth transition structure without dead angles, and the materials and the structure can be conveniently cleaned, so that the sterilization is more thorough.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the utility model. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (18)

1. A solid-liquid two-phase gel stirring and filling system is characterized by comprising a stirring device (1), a pumping device (2) and a filling device (3);
the stirring device (1) comprises a gel container (11), a stirring paddle (12) and a driving motor (13), gel is stored in the gel container (11), the lower part of the stirring paddle (12) extends into the gel container (11), and the driving motor (13) drives the stirring paddle (12) to rotate so as to stir the gel in the gel container (11);
the filling device (3) comprises a lifting driver (31) and a positioning needle seat (32), wherein the positioning needle seat (32) is used for clamping a filling needle module (33), and the lifting driver (31) can drive the positioning needle seat (32) to move up and down to enable the filling needle to correspond to the microcolumn into which the microcolumn gel reagent card is inserted;
each filling needle on the filling needle module (33) is connected to the gel container (11) through a glue conveying pipeline (4), and the pumping device (2) is arranged on the glue conveying pipeline (4) and used for pumping glue liquid in the gel container (11) to the filling needle module (33).
2. The stirring and filling system for solid-liquid two-phase gel according to claim 1, wherein at least two groups of the gel containers (11) and the stirring paddles (12) are provided, the stirring paddles (12) and the driving motor (13) are driven by a belt, a chain or a gear, and the stirring paddles (12) can drive the next-stage stirring paddles (12) to rotate.
3. The stirring and filling system for solid-liquid two-phase gel according to claim 2, wherein the stirring paddle (12) comprises a transmission shaft (121), a hollow shaft (122) and a driven pulley (123), the transmission shaft (121) is inserted into the inner cavity of the hollow shaft (122), and the driven pulley (123) is circumferentially fixed on the hollow shaft (122);
the transmission shaft (121) can move axially relative to the hollow shaft (122), and a paddle (124) is arranged at the lower part of the transmission shaft (121).
4. The stirring and filling system for solid-liquid two-phase gel according to claim 3, wherein the hollow shaft (122) is mounted on a bearing housing (5) by means of at least two rotary bearings (51).
5. The stirring and filling system for solid-liquid two-phase gel according to claim 4, wherein the transmission shaft (121) and the hollow shaft (122) are connected by a flat key or a spline; the hollow shaft (122) is connected with the driven pulley (123) through a flat key or a spline;
the transmission shaft (121) is detachably and fixedly provided with a fixed limiting ring (125), and the lower surface of the fixed limiting ring (125) is in contact with the bearing seat (5) to realize axial limiting.
6. The solid-liquid two-phase gel stirring and filling system according to claim 5, wherein the driven pulley (123) or the hollow shaft (122) is provided with a ball plunger (126) in a radial direction, the ball plunger (126) comprises a movable inner core and a fixed outer shell, the fixed outer shell is fixed to the hollow shaft (122), the movable inner core can move in the radial direction, an elastic member is arranged between the movable inner core and the fixed outer shell, and the movable inner core is subjected to elastic force towards the transmission shaft (121) and can be pressed against a positioning groove arranged on the transmission shaft (121) to realize axial positioning.
7. The stirring and filling system for solid-liquid two-phase gel according to claim 3, wherein the transmission shaft (121) comprises an upper section and a lower section which are clamped with each other, and the paddle (124) is arranged on the lower section.
8. The stirring and filling system for solid-liquid two-phase gel according to claim 3, wherein the paddles (124) are arranged in at least two groups along the axial direction, and each group of the paddles (124) has an included angle in the circumferential direction.
9. The stirring and filling system for solid-liquid two-phase gel according to claim 1, wherein the filling device (3) comprises a guide plate (34) slidably fitted on the positioning needle seat (32), and the filling needle on the filling needle module (33) can pass through the guide plate (34); the guide plate (34) is provided with a positioning shaft sleeve (341) in a downward protruding mode, and the positioning shaft sleeve (341) can be inserted into a micro-column on the micro-column gel reagent card to achieve circumferential adjustment.
10. The stirring and filling system for solid-liquid two-phase gel according to claim 9, wherein at least two guide shafts (342) are vertically arranged on the guide plate (34), and the guide shafts (342) are inserted into the positioning needle seats (32) in a guiding manner.
11. The stirring and filling system for solid-liquid two-phase gel according to claim 10, wherein a return spring (343) is disposed between the guiding shaft (342) and the positioning needle seat (32), and the return spring (343) can apply downward elastic force to the guiding shaft (342).
12. The stirring and filling system for solid-liquid two-phase gel according to claim 9, wherein a hose arranging block (35) is disposed at an upper portion of the positioning needle seat (32), and each filling needle of the filling needle module (33) corresponds to a through hole of the hose arranging block (35) for the glue pipeline (4) to pass through.
13. The stirring and filling system for solid-liquid two-phase gel according to claim 12, wherein identification marks are engraved or etched on the surface of the hose tidying block (35), and each identification mark correspondingly distinguishes the glue conveying pipeline (4) connected with one filling needle.
14. The solid-liquid two-phase gel agitation filling system according to any one of claims 1 to 13, wherein said pumping device (2) comprises a filling motor (21), a filling pump head (22) and a grating sensor (23), said grating sensor (23) being configured to detect a number of rotations of said filling motor (21).
15. The stirring and filling system for solid-liquid two-phase gel according to claim 14, wherein the gel container (11) is provided with a tank cover, an automatic liquid supplementing system (6) is connected to the tank cover, and the gel is supplemented by matching with a liquid level sensor in the gel container (11).
16. The stirring and filling system for solid-liquid two-phase gel according to claim 15, wherein the filling motor (21) is a variable frequency motor, and the rotation speed of the filling motor is adaptively adjusted according to the conditions of the ingredients, viscosity and the residual amount of the gel liquid in the filling process.
17. The stirring and filling system for solid-liquid two-phase gel according to claim 14, wherein a liquid distributor (111) is provided at the liquid outlet at the bottom of the gel container (11), and the liquid distributor (111) can deliver gel to at least two sets of the filling devices (3).
18. The stirring and filling system for solid-liquid two-phase gel according to claim 17, wherein the gel container (11) is a borosilicate container; the liquid distributor (111) is a 304 or 306L stainless steel joint; the inner surface of the gel container (11), the outer surface of the stirring paddle (12) and the inner surface of the liquid distributor (111) are in smooth transition without dead angles.
CN202121752561.9U 2021-07-29 2021-07-29 Solid-liquid two-phase gel stirring and filling system Active CN215388793U (en)

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CN202121752561.9U CN215388793U (en) 2021-07-29 2021-07-29 Solid-liquid two-phase gel stirring and filling system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121752561.9U CN215388793U (en) 2021-07-29 2021-07-29 Solid-liquid two-phase gel stirring and filling system

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CN215388793U true CN215388793U (en) 2022-01-04

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