CN215385969U - Production device of high-purity mesalazine enteric-coated sustained-release tablet preparation - Google Patents
Production device of high-purity mesalazine enteric-coated sustained-release tablet preparation Download PDFInfo
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- CN215385969U CN215385969U CN202022938750.7U CN202022938750U CN215385969U CN 215385969 U CN215385969 U CN 215385969U CN 202022938750 U CN202022938750 U CN 202022938750U CN 215385969 U CN215385969 U CN 215385969U
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Abstract
The utility model relates to the field of preparation production, and discloses a production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation, which adopts the technical scheme that the device comprises a quantitative reaction tank, wherein the top of the quantitative reaction tank is provided with a plurality of feed holes in a penetrating manner, the outer sides of the feed holes are connected with feed pipelines, the joints of the feed pipelines and the feed holes are provided with electric feed valves, and the insides of the electric feed valves are provided with flow meters; the top of the quantitative reaction tank is also provided with a gas discharge hole in a penetrating way, and the outer side of the gas discharge hole is connected with a gas treatment pipeline in a matching way; inside dispose the rabbling mechanism of quantitative retort, the bottom of quantitative retort disposes the discharge gate, the discharge gate is external to have the discharging pipe, the discharging pipe with the junction of discharge gate disposes electronic ejection of compact valve, can add to the ration of various raw materials for production, can more advance accurate assurance feeding volume, the actual production of being convenient for.
Description
Technical Field
The utility model relates to the field of preparation production, in particular to a production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation.
Background
Mesalazine enteric sustained release tablets, the name of western medicine. It is effective in relieving inflammation and pain. Can be used for acute phase treatment of ulcerative colitis (inflammation with ulcer), maintenance therapy for preventing recurrence, and symptom improvement therapy of active Crohn's disease.
In the production process of the high-purity mesalazine enteric-coated sustained-release tablet preparation, various production raw materials need to be stirred and mixed for reaction so as to obtain a final reagent finished product. In actual production process, need carry out the ration to multiple raw materials and add, present most manufacturing enterprise still adopts artifical ration to add, but the production mode of artifical adding can lead to production efficiency low, and receives manual operation precision to influence greatly.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation, which can quantitatively add various production raw materials, can accurately control the feeding amount and is convenient for actual production.
The technical purpose of the utility model is realized by the following technical scheme: a production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation is characterized in that: the quantitative reaction tank is characterized by comprising a quantitative reaction tank, wherein a plurality of feeding holes are formed in the top of the quantitative reaction tank in a penetrating manner, the outer sides of the feeding holes are connected with feeding pipelines, electric feeding valves are arranged at the joints of the feeding pipelines and the feeding holes, and flow meters are arranged inside the electric feeding valves;
the top of the quantitative reaction tank is also provided with a gas discharge hole in a penetrating way, and the outer side of the gas discharge hole is connected with a gas treatment pipeline in a matching way;
inside dispose the rabbling mechanism of quantitative retort, the bottom of quantitative retort disposes the discharge gate, the discharge gate is external to have the discharging pipe, the discharging pipe with the junction of discharge gate disposes electronic ejection of compact valve.
As a preferred technical scheme of the utility model, the quantitative reaction tank comprises a tank top plate, a side wall cylinder and a bottom conical cylinder which are sequentially and correspondingly connected in a sealing manner from top to bottom.
As a preferred technical solution of the present invention, the gas exhaust hole is disposed on the tank top plate, an air extractor is further disposed on the tank top plate, a gas inlet end of the air extractor is correspondingly communicated with the gas exhaust hole, and a gas outlet end of the air extractor is correspondingly communicated with the gas processing pipeline.
As a preferred technical scheme of the present invention, the stirring mechanism includes a rotating electrical machine, a stirring center shaft, a horizontal extension plate, and a plurality of stirring rods, a fixed portion of the rotating electrical machine is fixedly connected to the tank top plate, a rotating portion of the rotating electrical machine is fixedly connected to a top end of the stirring center shaft, a bottom end of the stirring center shaft is fixedly connected to a middle portion of a top surface of the horizontal extension plate, a plurality of stirring rods are uniformly connected to a bottom edge of the horizontal extension plate, and top ends of the stirring rods are fixedly connected to the horizontal extension plate.
In a preferred embodiment of the present invention, the stirring rod includes an outer sleeve rod, and an internal heating mechanism is disposed inside the outer sleeve rod.
As a preferred technical scheme of the utility model, the internal heating mechanism comprises a top fixed seat, an electric heating rod and heat transfer liquid; the fixed cover of top fixing base is established the top inboard of outer loop bar, the top of electrical heating stick with the bottom fixed connection of top fixing base, heat transfer liquid is filled outer loop bar top fixing base and in the cavity between the electrical heating stick.
As a preferable technical solution of the present invention, one end of the feeding pipe connected to the electric feeding valve is located at the lowest position of the whole feeding pipe body.
As a preferable technical scheme of the utility model, the caliber of the top end of the bottom conical cylinder is larger than that of the bottom end, and the bottom end of the bottom conical cylinder is provided with the discharge hole.
In conclusion, the utility model has the following beneficial effects: in apparatus for producing's working process, can accomplish the ration to various manufacturing raw materials and add through control electronic feed valve and flowmeter, adopt machine control, can more add accurate assurance feeding volume, the actual production of being convenient for.
Drawings
FIG. 1 is a schematic structural view of the present invention;
in the figure: 1. a quantitative reaction tank; 2. a feed port; 3. a feed conduit; 4. an electric feed valve; 5. a gas discharge hole; 6. a gas treatment line; 7. a top fixed seat; 8. a discharge port; 9. an electric discharge valve; 10. an air extractor; 11. a rotating electric machine; 12. stirring the middle shaft; 13. a laterally extending plate; 14. a stirring rod.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
As shown in fig. 1, the utility model provides a production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation, which comprises a quantitative reaction tank 1, wherein the top of the quantitative reaction tank 1 is provided with a plurality of feed holes 2 in a penetrating manner, the outer sides of the feed holes 2 are connected with feed pipelines 3, the joints of the feed pipelines 3 and the feed holes 2 are provided with electric feed valves 4, the electric feed valves 4 are internally provided with flow meters, and the production device is mainly used for production reaction of fluid production raw materials;
the top of the quantitative reaction tank 1 is also provided with a gas discharge hole 5 in a penetrating way, the outer side of the gas discharge hole 5 is connected with a gas processing pipeline 6 in a matching way, and the gas discharge hole 5 is positioned at the topmost end so as to be convenient for discharging gas generated in the reaction process;
1 inside disposes rabbling mechanism of quantitative retort 1, and the bottom of quantitative retort 1 disposes discharge gate 8, and discharge gate 8 is external to have the discharging pipe, and the junction of discharging pipe and discharge gate 8 disposes electronic discharge valve 9.
It should be noted that the production apparatus of the present invention is a link of the whole production system, the whole production system is provided with a control unit, that is, the power devices in the production apparatus are all connected with corresponding controllers, for example, the electric feeding valve 4, the flow meter, the stirring mechanism and the electric discharging valve 9 are all connected with corresponding controllers, when the feeding is controlled, the operator can monitor that the feeding amount measured by the flow meter reaches a set value by setting the controllers, and then control the electric feeding valve 4 to close, so that the quantitative feeding effect can be achieved, and the machine control can be more accurate, which is convenient for practical use.
The working principle and the using process of the utility model are as follows: each feeding pipeline 3 is connected into a corresponding raw material storage tank in advance, and control parameters are set for a control unit of the production device; when the quantitative reaction tank is actually used, firstly, the electric feeding valve 4 is opened, so that production raw materials in each feeding pipeline 3 can be poured into the quantitative reaction tank 1, the flow meter is always in work in the process that the production raw materials enter the quantitative reaction tank 1, the entering amount of the raw materials is measured, and after the production raw materials reach the set amount, the electric feeding valve 4 is closed; after all the production raw materials are fed, starting a stirring mechanism to stir and mix the production raw materials in the quantitative reaction tank 1, discharging the gas of the reaction from the gas discharge hole 5 in the mixing reaction process, and after the production raw materials are reacted, opening the electric discharge valve 9 to discharge the reacted reactants to finish the production reaction. In apparatus for producing's working process, can accomplish the ration to various raw materials for production and add through control electronic feed valve 4 and flowmeter, adopt machine control, can more add accurate assurance feeding volume, the actual production of being convenient for.
As a specific embodiment of the utility model, the quantitative reaction tank 1 comprises a tank top plate, a side wall cylinder and a bottom conical cylinder which are sequentially and correspondingly hermetically connected from top to bottom, the caliber of the top end of the bottom conical cylinder is larger than that of the bottom end, the bottom end of the bottom conical cylinder is provided with a discharge hole 8, and the whole bottom conical cylinder is funnel-shaped integrally, so that centralized discharge can be facilitated, and the quantitative reaction tank is convenient for practical production and use.
As a specific embodiment of the present invention, the gas exhaust hole 5 is disposed on a top plate of the tank, the top plate of the tank is further provided with an air pump 10, an air inlet end of the air pump 10 is correspondingly communicated with the gas exhaust hole 5, an air outlet end of the air pump 10 is correspondingly communicated with the gas processing pipeline 6, the air pump 10 can accelerate the exhaust of the gas in the quantitative reaction tank 1, and the gas accumulation in the quantitative reaction tank 1 is avoided, so as to prevent the quantitative reaction tank 1 from being damaged; simultaneously, air extractor 10 can also be used for using when the raw materials for production feeding for produce the negative pressure in the quantitative retort 1, thereby the feeding of raw materials for production with higher speed, especially when having the raw materials for production to be the colloid object, air extractor 10 can accelerate the input speed of colloid raw materials for production by a wide margin, the in-service use of being convenient for more.
As a specific embodiment of the present invention, the stirring mechanism includes a rotating electrical machine 11, a stirring central shaft 12, a horizontal extension plate 13 and a plurality of stirring rods 14, a fixed portion of the rotating electrical machine 11 is fixedly connected with a tank top plate, a rotating portion of the rotating electrical machine 11 is fixedly connected with a top end of the stirring central shaft 12, a bottom end of the stirring central shaft 12 is fixedly connected with a middle portion of a top surface of the horizontal extension plate 13, a plurality of stirring rods 14 are uniformly connected to a bottom edge of the horizontal extension plate 13, and a top end of each stirring rod 14 is fixedly connected with the horizontal extension plate 13, when the rotating electrical machine 11 of the stirring mechanism works, the stirring central shaft 12 and the horizontal extension plate 13 can be driven to rotate, and further the stirring rods 14 are driven to stir in the quantitative reaction tank 1, so as to achieve a stirring and mixing effect on production raw materials.
As a specific embodiment of the present invention, the stirring rod 14 includes an outer sleeve rod, an internal heating mechanism is disposed inside the outer sleeve rod, and the internal heating mechanism includes the top fixing seat 7, the electric heating rod and the heat transfer liquid; the top fixing seat 7 is fixedly sleeved on the inner side of the top of the outer loop bar, the top end of the electric heating rod is fixedly connected with the bottom end of the top fixing seat 7, and heat transfer liquid is filled in a cavity among the outer loop bar, the top fixing seat 7 and the electric heating rod.
When the reaction is required to be heated, the internal heating mechanism is started, the electric heating rod is heated, the heat transfer liquid is heated, and the outer sleeve rod is heated, so that the production raw materials in direct contact with the outer sleeve rod can be heated, and the effect of heating for the reaction is achieved.
As a specific embodiment of the utility model, one end of the feeding pipeline 3 connected with the electric feeding valve 4 is positioned at the lowest part of the whole feeding pipeline 3 body, so that the feeding is convenient, and the practical production and use are convenient.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the utility model may occur to those skilled in the art without departing from the principle of the utility model, and are considered to be within the scope of the utility model.
Claims (8)
1. A production device of a high-purity mesalazine enteric-coated sustained-release tablet preparation is characterized in that: the quantitative reaction tank comprises a quantitative reaction tank (1), wherein a plurality of feeding holes (2) are formed in the top of the quantitative reaction tank (1) in a penetrating mode, a feeding pipeline (3) is connected to the outer side of each feeding hole (2), an electric feeding valve (4) is arranged at the joint of each feeding pipeline (3) and the corresponding feeding hole (2), and a flow meter is arranged inside each electric feeding valve (4);
the top of the quantitative reaction tank (1) is also provided with a gas discharge hole (5) in a penetrating way, and the outer side of the gas discharge hole (5) is connected with a gas treatment pipeline (6) in a matching way;
quantitative retort (1) inside disposes rabbling mechanism, the bottom of quantitative retort (1) disposes discharge gate (8), discharge gate (8) are external to have the discharging pipe, the discharging pipe with the junction of discharge gate (8) disposes electronic ejection of compact valve (9).
2. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 1, which is characterized in that: the quantitative reaction tank (1) comprises a tank top plate, a side wall cylinder and a bottom conical cylinder which are sequentially and correspondingly connected in a sealing manner from top to bottom.
3. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 2, which is characterized in that: the gas exhaust hole (5) is formed in the tank top plate, the tank top plate is further provided with an air pump (10), the gas inlet end of the air pump (10) is correspondingly communicated and connected with the gas exhaust hole (5), and the gas outlet end of the air pump (10) is correspondingly communicated and connected with the gas processing pipeline (6).
4. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 2, which is characterized in that: the stirring mechanism comprises a rotating motor (11), a stirring center shaft (12), a transverse extension plate (13) and a plurality of stirring rods (14), wherein a fixed part of the rotating motor (11) is fixedly connected with the tank top plate, a rotating part of the rotating motor (11) is fixedly connected with the top end of the stirring center shaft (12), the bottom end of the stirring center shaft (12) is fixedly connected with the middle of the top surface of the transverse extension plate (13), the bottom surface edge of the transverse extension plate (13) is uniformly connected with the stirring rods (14), and the top end of each stirring rod (14) is fixedly connected with the transverse extension plate (13).
5. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 4, which is characterized in that: the stirring rod (14) comprises an outer sleeve rod, and an internal heating mechanism is arranged in the outer sleeve rod.
6. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 5, which is characterized in that: the internal heating mechanism comprises a top fixed seat (7), an electric heating rod and heat transfer liquid; the top fixing seat (7) is fixedly sleeved on the inner side of the top of the outer sleeve rod, the top end of the electric heating rod is fixedly connected with the bottom end of the top fixing seat (7), and the heat transfer liquid is filled in the outer sleeve rod, the top fixing seat (7) and a cavity between the electric heating rods.
7. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 1, which is characterized in that: the feeding pipeline (3) is connected with one end of the electric feeding valve (4) and is located at the lowest position of the whole feeding pipeline (3) body.
8. The production device of the high-purity mesalazine enteric sustained-release tablet preparation according to claim 2, which is characterized in that: the top end caliber of the bottom conical cylinder is larger than the bottom end caliber, and the discharge hole (8) is formed in the bottom end of the bottom conical cylinder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022938750.7U CN215385969U (en) | 2020-12-10 | 2020-12-10 | Production device of high-purity mesalazine enteric-coated sustained-release tablet preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022938750.7U CN215385969U (en) | 2020-12-10 | 2020-12-10 | Production device of high-purity mesalazine enteric-coated sustained-release tablet preparation |
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| Publication Number | Publication Date |
|---|---|
| CN215385969U true CN215385969U (en) | 2022-01-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202022938750.7U Active CN215385969U (en) | 2020-12-10 | 2020-12-10 | Production device of high-purity mesalazine enteric-coated sustained-release tablet preparation |
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| Country | Link |
|---|---|
| CN (1) | CN215385969U (en) |
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- 2020-12-10 CN CN202022938750.7U patent/CN215385969U/en active Active
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