CN215308925U - Light-resistant extracorporeal circulation blood circuit of blood purification device - Google Patents
Light-resistant extracorporeal circulation blood circuit of blood purification device Download PDFInfo
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- CN215308925U CN215308925U CN202120207999.2U CN202120207999U CN215308925U CN 215308925 U CN215308925 U CN 215308925U CN 202120207999 U CN202120207999 U CN 202120207999U CN 215308925 U CN215308925 U CN 215308925U
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Abstract
The utility model discloses a light-resistant extracorporeal circulation blood circuit of a blood purification device, which comprises an arterial pipeline and a venous pipeline and is characterized in that a pre-filling branch catheter is provided with a precise liquid medicine filter, and the precise liquid medicine filter consists of a liquid medicine inlet, a liquid medicine filtering membrane, a liquid medicine outlet, a shell of the precise liquid medicine filter, an air vent, a breathable membrane, a side interface with external threads and a protective cap. After the precise liquid medicine filter finishes exhausting, the protective cap is screwed to prevent gas from entering, so that the pollution of insoluble particles to a dialysis patient in treatment can be reduced; the utility model also has the advantages that the damage to the human body caused by photochemical reaction generated by the light irradiation of the photosensitive substance and the photosensitive medicine in the blood is avoided, the damage to blood cells caused by the light is avoided, and part of visible light can be transmitted for the observation in the treatment; avoiding the contact of medical personnel with the light-resistant agent, avoiding the pollution of the light-resistant agent to the environment and the like.
Description
Technical Field
The utility model relates to a medical apparatus, in particular to a light-resistant extracorporeal circulation blood circuit of a blood purification device.
Background
Hemodialysis is one of the kidney replacement treatment modes of patients with acute and chronic renal failure. It needs to drain the blood in vivo to the outside of the body for treatment, so as to eliminate the metabolic waste in the body and maintain the balance of electrolytes and acid-base; and simultaneously, excessive water in the body is removed. The extracorporeal circulation blood path of the blood purification device is an apparatus for establishing a blood channel in hemodialysis treatment, and is made of transparent materials, so that blood receives irradiation of non-physiological light during the hemodialysis treatment.
Blood contains many light-sensitive substances, such as bilirubin and mecobalamin. Bilirubin is an endogenous strong antioxidant, has strong antioxidant stress, free radical scavenging, oxygen injury relieving, lipid peroxidation inhibiting effects, and can protect atherosclerosis, coronary heart disease, inflammatory diseases, tumor, nephropathy, etc. under stress. Bilirubin is an important light receptor, can perform photochemical reaction after absorbing light, is converted into water-soluble bilirubin isomer from fat-soluble bilirubin, has great change in physiological function, is easy to dissolve in water and is easy to discharge out of a body. The hemodialysis treatment has strong capacity of removing water-soluble substances, and fat-soluble bilirubin is easy to remove by the dialysis treatment after being converted into water-soluble bilirubin isomers, so that the blood bilirubin level is reduced.
Some medicines (such as sodium nitroprusside injection, mecobalamin injection, glycerin nitrate injection, water-soluble vitamin injection, ofloxacin injection and the like) are easy to decompose after being exposed to light, so that the activity of the medicines is reduced, the curative effect of the medicines is seriously influenced, the toxicity of the medicines is increased, and serious patients even endanger life. The dialysis patients may use some photosensitive drugs, and the blood of the patients has a certain drug concentration, so that the photosensitive substances and the photosensitive drugs in the blood can absorb light during dialysis treatment, and a photochemical reaction occurs, thereby causing adverse effects on the patients.
The ultraviolet ray with the wavelength of 200-300nm, especially 265-266nm has strong killing effect, and can damage and kill cells irradiated by the ultraviolet ray. Riboflavin, also known as vitamin B2, is a photosensitive water-soluble vitamin contained in human blood, and under the photochemical action of riboflavin under the excitation of visible light or ultraviolet rays, the proliferation of lymphocytes can be inhibited, so that the lymphocytes lose the proliferation characteristics in form and function, and the lymphocytes die. Hypoimmunity in uremic dialysis patients is associated with shortened life span of lymphocytes, decreased total number of lymphocytes, and suppressed transformation of lymphocytes. In dialysis treatment, blood circulates in vitro in a transparent medical instrument and is irradiated by visible light and ultraviolet rays, so that damage to lymphocytes is inevitably increased.
The Chinese pharmacopoeia stipulates that the marking loading amount is 100 ml or more than 100 ml in intravenous injection, each ml contains more than 10 microns of particles and less than 25 particles, and contains more than 25 microns of particles and less than 3 particles, and the proportion of particles with 2 to 10 microns which have potential harm to human bodies is up to 98 percent. When priming operation of hemodialysis treatment, more than 800 ml of physiological saline is needed to be filled and the extracorporeal circulation blood circuit and the dialyzer of the blood purification device are flushed. When blood is drawn from the upper machine and returned from the lower machine, part of the normal saline enters the blood vessel of the human body along with the blood. The extracorporeal circulation blood circuit of the existing blood purification device has no precise liquid medicine filter, and a large amount of particles are inevitably led to enter the body of a dialysis patient along with normal saline after long-term use.
The existing precision liquid medicine filter is provided with an air vent, so that when the downstream pipeline is in a negative pressure state, air can enter the downstream pipeline through the air vent, and the priming operation and the blood returning operation of the blood purifying device fail due to the entering of the air.
Disclosure of Invention
The utility model aims to provide a light-resistant extracorporeal circulation blood circuit of a blood purification device, which can reduce the pollution of insoluble particles in physiological saline to dialysis patients in long-term and multiple treatments, has reasonable structure, simple composition and safe and reliable performance.
The purpose of the utility model is realized as follows:
a light-resistant extracorporeal circulation blood circuit of a blood purification device, comprising an arterial line and a venous line, wherein: the arterial line comprises an arterial dialyzer connector, an arterial gas capturer, a pump pipe and an arterial blood passage connector which are sequentially connected through an arterial blood conducting tube, wherein the arterial gas capturer is connected with a first branch conduit of the arterial gas capturer and a second branch conduit of the arterial gas capturer; the vein pipeline comprises a vein dialyzer joint, a vein gas trapper and a vein blood passage joint which are sequentially connected through a vein blood conducting pipe, the vein gas trapper is connected with a vein gas trapper branch pipe and a vein sensor protector pipeline, and the vein sensor protector pipeline is connected with a vein pressure measuring port of the hemodialysis machine through a vein sensor protector and can monitor the vein pressure in the vein sensor protector pipeline in real time; a vein pipeline sampling port is arranged on a pipeline between the connector of the vein dialyzer and the vein gas catcher, and a vein blood filter for filtering blood is arranged in the vein gas catcher; the arterial catheter, the arterial sensor protector pipeline, the pre-filling branch catheter, the heparin branch catheter, the arterial gas trapper first branch catheter, the arterial gas trapper second branch catheter, the venous sensor protector pipeline and the venous catheter are respectively provided with a switch pipe clamp;
is characterized in that: a precise liquid medicine filter is arranged on the pre-filling branch catheter and consists of a liquid medicine inlet, a liquid medicine filtering membrane, a liquid medicine outlet, a precise liquid medicine filter shell, an air vent, a breathable membrane, a side interface with external threads and a protective cap; one end of the front half section of the pre-charging branch conduit is a liquid inlet and is connected with a protective cap, the other end of the front half section of the pre-charging branch conduit is connected with a liquid medicine inlet of the precise liquid medicine filter, one end of the rear half section of the pre-charging branch conduit is connected with a liquid medicine outlet of the precise liquid medicine filter, and the other end of the rear half section of the pre-charging branch conduit is connected with one end of a pump pipe; a liquid medicine filtering membrane is arranged in a shell cavity of the shell of the precise liquid medicine filter and between a liquid medicine inlet and a liquid medicine outlet, an air vent communicated with the shell cavity is arranged on the side wall of the shell of the precise liquid medicine filter, a breathable membrane is arranged between the air vent and the shell cavity, a side interface with external threads is arranged at the outward end of the air vent, and a protective cap with internal threads is connected with the side interface with external threads in a threaded connection mode.
The artery vessel, artery gas capturer, pump pipe in the artery pipeline and vein vessel, vein gas capturer in the vein pipeline are all three-layer structure, the outer layer is anti-drop layer, the middle layer is light-resistant layer made of medical plastics containing light-resistant agent, the light-resistant wavelength range value is 250-550 nm, and the inner layer is transparent layer without light-resistant agent.
The artery dialyzer joint, the artery blood passage joint, the vein dialyzer joint and the vein blood passage joint are made of light-proof materials.
The utility model has the following advantages:
1. the pre-filling branch pipe in front of the pump pipe is provided with the precise liquid medicine filter, the air hole of the precise liquid medicine filter is externally provided with the side interface with the external thread and the protective cap with the internal thread, and the protective cap can be screwed after the precise liquid medicine filter finishes exhausting, so that gas is prevented from entering a downstream pipeline, and the operation safety is guaranteed. When the priming operation and the blood returning from the machine are carried out, the normal saline is filtered by the precise liquid medicine filter, so that the pollution of insoluble particles in the normal saline to a dialysis patient in long-term and multiple treatments can be reduced.
2. When a patient needs to input some medicines into the extracorporeal circulation blood path through the pre-filling branch catheter in the dialysis treatment process, the function of filtering liquid medicine can be achieved;
3. the artery vessel, artery gas capturer, pump pipe in the artery pipeline and vein vessel, vein gas capturer in the vein pipeline are all three-layer structure, the outer layer is anti-drop layer, the middle layer is light-resistant layer made of medical plastics containing light-resistant agent, the light-resistant wavelength range value is 250-550 nm, and the inner layer is transparent layer without light-resistant agent. The artery dialyzer joint, the artery blood passage joint, the vein dialyzer joint and the vein blood passage joint are made of light-proof materials. When the blood is in extracorporeal circulation in a light-proof extracorporeal circulation blood circuit of the blood purification device, light with the wavelength range of 250-550 nm is shielded, and the damage to a human body caused by photochemical reaction of light-sensitive substances and photosensitive drugs in the blood through light irradiation is avoided; the damage of light to blood cells is avoided; but also can transmit partial visible light for observation in treatment;
4. the outer layer is an anti-drop layer, which avoids the contact of medical personnel and the light-resistant agent and avoids the pollution of the light-resistant agent to the environment;
5. reasonable structure, simple composition and safe and reliable performance.
Drawings
FIG. 1 is a schematic diagram of the arterial line of the present invention;
FIG. 2 is a schematic diagram of the intravenous line of the present invention;
FIG. 3 is a precise liquid medicine filter;
fig. 4 is a cross-sectional view of the arterial catheter, arterial gas trap, pump tube, venous catheter, venous gas trap.
Detailed Description
The present invention will be described in further detail with reference to the following examples and drawings.
A light-resistant extracorporeal circulation blood circuit of a blood purification device, comprising an arterial line and a venous line, wherein: the arterial pipeline comprises an arterial dialyzer connector 101, an arterial gas capturer 103, a pump pipe 104 and an arterial blood passage connector 106 which are sequentially connected through an arterial blood conducting pipe 102, the arterial gas capturer 103 is connected with an arterial gas capturer first branch conduit 110 and an arterial gas capturer second branch conduit 111, one end of the pump pipe 104 is connected with a heparin branch conduit 109, the other end of the pump pipe 104 is connected with a pre-filling branch conduit 108 (one end of the front half section of the pre-filling branch conduit 108 is a liquid inlet and is connected with a protective cap, the other end of the front half section is connected with a precise liquid medicine filter liquid medicine inlet 405, one end of the rear half section of the pre-filling branch conduit 108 is connected with a precise liquid medicine filter liquid medicine outlet 407, the other end of the rear half section is connected with the pump pipe 104) and an arterial sensor protector pipeline 107, the arterial sensor protector pipeline 107 is connected with an arterial pressure measuring port of the hemodialysis machine through an arterial sensor protector 115, the arterial pressure in the arterial sensor protector pipeline 107 can be monitored in real time, an arterial pipeline sampling port 112 is arranged on the pipeline between the arterial blood access joint 106 and the pump pipe 104, and an arterial blood filter 113 for filtering blood is arranged in the arterial gas catcher 103; the venous line comprises a venous dialyzer connector 201, a venous gas capturer 204 and a venous blood access connector 208 which are sequentially connected through a venous blood conducting tube 203, the venous gas capturer 204 is connected with a venous gas capturer branch catheter 205 and a venous sensor protector pipeline 206, the venous sensor protector pipeline 206 is connected with a venous pressure measuring port of the hemodialysis machine through a venous sensor protector 210, and venous pressure in the venous sensor protector pipeline 206 can be monitored in real time; a vein pipeline sampling port 202 is arranged on a pipeline between the connector 201 of the vein dialyzer and the vein gas catcher 204, and a vein blood filter 209 for filtering blood is arranged in the vein gas catcher 204; an artery catheter 102, an artery sensor protector pipeline 107, a pre-filling branch catheter 108, a heparin branch catheter 109, an artery gas trap first branch catheter 110, an artery gas trap second branch catheter 111, a vein catheter 203, a vein gas trap branch catheter 205 and a vein sensor protector pipeline 206 between an artery blood passage joint 106 and an artery pump pipe 104 are respectively provided with a switch pipe clamp 300; a precise liquid medicine filter 114 is arranged on the pre-filling branch conduit 108, and the precise liquid medicine filter 114 is composed of a liquid medicine inlet 405, a liquid medicine filtering membrane 406, a liquid medicine outlet 407, a precise filter shell 408, an air vent 401, an air permeable membrane 404, a side interface 402 with external threads and a protective cap 403; one end of the front half section of the pre-filling branch conduit 108 is a liquid inlet and is connected with a protective cap, the other end of the front half section of the pre-filling branch conduit 108 is connected with a liquid medicine inlet 405 of the precise liquid medicine filter 114, one end of the rear half section of the pre-filling branch conduit 108 is connected with a liquid medicine outlet 407 of the precise liquid medicine filter 114, the other end of the rear half section of the pre-filling branch conduit 108 is connected with the pump pipe 104, a liquid medicine filtering membrane 406 is arranged in a shell cavity 409 of a shell 408 of the precise liquid medicine filter between the liquid medicine inlet 405 and the liquid medicine outlet 407, a vent hole 401 communicated with the shell cavity 409 is arranged on the side wall of the shell 408 of the precise liquid medicine filter, a breathable membrane 404 is arranged between the vent hole 401 and the shell cavity 409, a side interface 402 with external threads is arranged at the outward end of the vent hole 401, and the protective cap 403 with the internal threads is connected with the side interface 402 with the external threads in a threaded manner.
The artery vessel 102, artery gas capturer 103, pump line 104 in the artery pipeline, vein vessel 203 and vein gas capturer 204 in the vein pipeline are all formed by three layers, the outer layer 301 is an anti-drop layer, the middle layer 302 is a light-resistant layer made of medical plastics containing a light-resistant agent, the light-resistant wavelength range value is 250-550 nm, and the inner layer 303 is a transparent layer without the light-resistant agent.
The arterial dialyzer connector 101, the arterial blood passage connector 106, the venous dialyzer connector 201, and the venous blood passage connector 208 are made of light-resistant materials.
Claims (2)
1. A light-resistant extracorporeal circulation blood circuit of a blood purification device, comprising an arterial line and a venous line, wherein: the arterial line comprises an arterial dialyzer connector, an arterial gas capturer, a pump pipe and an arterial blood passage connector which are sequentially connected through an arterial blood conducting tube, wherein the arterial gas capturer is connected with a first branch conduit of the arterial gas capturer and a second branch conduit of the arterial gas capturer; the vein pipeline comprises a vein dialyzer joint, a vein gas trapper and a vein blood passage joint which are sequentially connected through a vein blood conducting pipe, the vein gas trapper is connected with a vein gas trapper branch pipe and a vein sensor protector pipeline, and the vein sensor protector pipeline is connected with a vein pressure measuring port of the hemodialysis machine through a vein sensor protector and can monitor the vein pressure in the vein sensor protector pipeline in real time; a vein pipeline sampling port is arranged on a pipeline between the connector of the vein dialyzer and the vein gas catcher, and a vein blood filter for filtering blood is arranged in the vein gas catcher; the arterial catheter, the arterial sensor protector pipeline, the pre-filling branch catheter, the heparin branch catheter, the arterial gas trapper first branch catheter, the arterial gas trapper second branch catheter, the venous sensor protector pipeline and the venous catheter are respectively provided with a switch pipe clamp;
the method is characterized in that: a precise liquid medicine filter is arranged on the pre-filling branch catheter and consists of a liquid medicine inlet, a liquid medicine filtering membrane, a liquid medicine outlet, a precise liquid medicine filter shell, an air vent, a breathable membrane, a side interface with external threads and a protective cap; one end of the front half section of the pre-filling branch conduit is a liquid inlet and is connected with a protective cap, the other end of the front half section of the pre-filling branch conduit is connected with a liquid medicine inlet of a precise liquid medicine filter, one end of the rear half section of the pre-filling branch conduit is connected with a liquid medicine outlet of the precise liquid medicine filter, the other end of the rear half section of the pre-filling branch conduit is connected with one end of a pump pipe, a liquid medicine filtering membrane is arranged in a shell cavity of a shell of the precise liquid medicine filter between the liquid medicine inlet and the liquid medicine outlet, a vent hole communicated with the shell cavity is formed in the side wall of the shell of the precise liquid medicine filter, a breathable membrane is arranged between the vent hole and the shell cavity, a side interface with external threads is arranged at the outward end of the vent hole, and the protective cap with the internal threads is connected with the side interface with the external threads in a threaded connection mode.
2. The light-shielding extracorporeal circulation blood circuit of the blood purification apparatus according to claim 1, characterized in that: the artery blood vessel, artery gas capturer, artery pump pipe in the artery pipeline and vein blood vessel, vein gas capturer in the vein pipeline are all three-layer structure, the outer layer is the anti-drop layer, the middle layer is the light-resistant layer made of medical plastics containing light-resistant agent, the light-resistant wavelength range value is 250-550 nm, the inner layer is the transparent layer without light-resistant agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120207999.2U CN215308925U (en) | 2021-01-26 | 2021-01-26 | Light-resistant extracorporeal circulation blood circuit of blood purification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120207999.2U CN215308925U (en) | 2021-01-26 | 2021-01-26 | Light-resistant extracorporeal circulation blood circuit of blood purification device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215308925U true CN215308925U (en) | 2021-12-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120207999.2U Expired - Fee Related CN215308925U (en) | 2021-01-26 | 2021-01-26 | Light-resistant extracorporeal circulation blood circuit of blood purification device |
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| Country | Link |
|---|---|
| CN (1) | CN215308925U (en) |
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2021
- 2021-01-26 CN CN202120207999.2U patent/CN215308925U/en not_active Expired - Fee Related
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Granted publication date: 20211228 |