CN215260826U - Freeze-drying device is used in polypeptide production - Google Patents
Freeze-drying device is used in polypeptide production Download PDFInfo
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- CN215260826U CN215260826U CN202121465304.7U CN202121465304U CN215260826U CN 215260826 U CN215260826 U CN 215260826U CN 202121465304 U CN202121465304 U CN 202121465304U CN 215260826 U CN215260826 U CN 215260826U
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- wall
- supporting plate
- freeze
- drying
- polypeptide production
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 25
- 238000004108 freeze drying Methods 0.000 title claims abstract description 24
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 21
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 19
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 19
- 238000001035 drying Methods 0.000 claims abstract description 42
- 239000000463 material Substances 0.000 claims abstract description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 4
- 238000007710 freezing Methods 0.000 claims description 4
- 230000008014 freezing Effects 0.000 claims description 4
- 238000005086 pumping Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000005265 energy consumption Methods 0.000 abstract description 3
- 238000005057 refrigeration Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000011344 liquid material Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000012254 powdered material Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
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- Drying Of Solid Materials (AREA)
Abstract
The utility model discloses a freeze-drying device is used in polypeptide production belongs to polypeptide production technical field. The utility model discloses a freeze drying device for polypeptide production, including the drying cabinet, be provided with evacuation system and refrigeration system in the drying cabinet, the top of drying cabinet is dug has the feed inlet, swing joint has the apron in the feed inlet, be connected with a plurality of tray spare between the inner wall of drying cabinet both sides, the bottom of a plurality of tray spare all is connected with the hot plate, the top of every tray spare all swing joint has the threaded rod, threaded rod outer wall threaded connection has the link plate, the bottom of link plate is connected with the receiving agencies, two adjacent threaded rod outer walls are connected with matched with synchronizing wheel, be connected with the belt between two synchronizing wheels, the drying cabinet outer wall is connected with the supporting seat, the supporting seat outer wall is connected with the driving source, the output of driving source passes the drying cabinet and links to each other with one of them threaded rod, and then can get and put the material fast, reduce staff's intensity of labour, and then improve production efficiency, the production energy consumption is reduced.
Description
Technical Field
The utility model relates to a polypeptide production technical field especially relates to a freeze-drying device is used in polypeptide production.
Background
Adopt among the prior art to disinfect protein, enzymolysis, separation, after concentrating, through freeze drying equipment, moisture sublimate into the gaseous state from solid-state in the liquid material promptly in vacuum environment, make peptide powder with getting rid of moisture, and freeze drying device adopts different multilayer charging tray structures among the prior art, material layer height is higher in the large-scale production process, it places to need staff one deck when putting the material, it collects to need the one deck equally when getting the material, whole process is wasted time and energy, and staff's intensity of labour has been improved, lead to polypeptide production machining efficiency lower.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the problem of wasting time in the process of freeze-drying materials in the prior art, and providing a freeze-drying device for producing polypeptide.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model discloses a freeze-drying device is used in peptide production, including the drying cabinet, be provided with evacuation system and refrigerating system in the drying cabinet, the top of drying cabinet is excavated there is the feed inlet, swing joint has the apron in the feed inlet, be connected with a plurality of support plates between the inner wall of drying cabinet both sides, it is a plurality of the bottom of holding in the palm the plate all is connected with the hot plate, every the equal swing joint in top of holding in the palm the plate has the threaded rod, threaded rod outer wall threaded connection has even board, the bottom of even board is connected with receiving agencies, two is adjacent threaded rod outer wall connection has matched with synchronizing wheel, two be connected with the belt between the synchronizing wheel, drying cabinet outer wall connection has the supporting seat, supporting seat outer wall connection has the driving source, the output of driving source passes the drying cabinet and links to each other with one of them threaded rod.
Preferably, the drying cabinet includes "mouthful" word frame and two curb plates, two the curb plate passes through bolt symmetry and connects in the both sides of "mouthful" word frame, just layer board spare is connected between two curb plates.
Preferably, the supporting plate pieces are provided with 6 small supporting plates and a large supporting plate, 6 arc-shaped grooves which are uniformly distributed are chiseled on the inner wall of the square frame, and the 6 arc-shaped grooves correspond to the small supporting plates one by one.
Preferably, the small supporting plate comprises a supporting plate bottom and two supporting plates, the two supporting plates are rotatably connected to two sides of the supporting plate bottom, sealing gaskets are connected to two sides of the supporting plate bottom, and an elastic telescopic rod is arranged between the supporting plates and the supporting plate bottom.
Preferably, the receiving mechanism comprises a swing rod, the swing rod is rotatably connected to the bottom of the connecting plate through a pin shaft, elastic elements are connected to the outer walls of the two sides of the swing rod, one end, far away from the swing rod, of each elastic element is connected to the bottom of the connecting plate, a brush is connected to the bottom of the swing rod, and the brush is movably abutted to the small supporting plate.
Preferably, the vacuum pumping system comprises a water-gas condenser, the water-gas condenser is connected to the outer wall of the drying box, the outer wall of the water-gas condenser is connected with a vacuum pump, the water-gas condenser is connected with the drying box through a pipeline, the freezing system comprises a refrigerator, the refrigerator is connected to the bottom of the drying box, and the inner wall of the drying box is connected with a plurality of refrigerating pipes which are connected with the refrigerator.
Has the advantages that: compared with the prior art, the utility model has the advantages that:
1. this freeze-drying device is used in polypeptide production, through on dropping into the layer board of the top with the material from the feed inlet, the material is liquid can the successive layer fall on the layer board spare, realize placing fast of material, material freeze-drying back, make the driving source drive the threaded rod and rotate, and then make its outside threaded connection's even board drive receiving agencies and strike off the powdery material on the layer board, make the material fall on the big layer board of below, the device is still can get the material fast, staff's intensity of labour is reduced, and then improve production efficiency, reduce the production energy consumption.
2. This freeze-drying device is used in polypeptide production can make the receiving agencies work of bottom through the removal of even board, when making the swinging arms removal, elastic component one of both sides is tensile, and a shrink makes the brush of swinging arms bottom closely laminate at the bottom of with the layer board, improves the effect that the powdered material was cleared up to the brush.
3. This freeze-drying device is used in polypeptide production through setting up the drying cabinet into "mouthful" word frame and two curb plates, when the material after the freeze-drying is taken out to needs, dismantles two curb plates from "mouthful" word frame, is convenient for take out fast and arranges the material in big layer board.
Drawings
Fig. 1 is a schematic structural view of the present invention;
fig. 2 is a schematic sectional structure view of the drying box of the present invention;
fig. 3 is a schematic structural diagram of a portion a in fig. 2 according to the present invention;
fig. 4 is a schematic structural view of the material receiving mechanism of the present invention;
fig. 5 is a schematic structural view of the small support plate of the present invention.
Detailed Description
As shown in fig. 1-5, the utility model discloses a freeze drying device is used in polypeptide production, including drying cabinet 1, be provided with evacuation system and refrigerating system in the drying cabinet 1, the top of drying cabinet 1 is opened and is chiseled there is feed inlet 1011, swing joint has apron 2 in the feed inlet 1011, be connected with a plurality of support plate spare 3 between the inner wall of 1 both sides of drying cabinet, the bottom of a plurality of support plate spare 3 all is connected with hot plate 303, the equal swing joint in top of every support plate spare 3 has threaded rod 4, threaded rod 4 outer wall threaded connection has even board 402, the bottom of even board 402 is connected with receiving agencies, 4 outer wall connections of two adjacent threaded rods have matched with synchronizing wheel 401, be connected with the belt between two synchronizing wheel 401, 1 outer wall connections of drying cabinet has supporting seat 5, 5 outer wall connections of supporting seat has driving source 6, the output of driving source 6 passes drying cabinet 1 and links to each other with one of them threaded rod 4.
The drying box 1 comprises a square frame 101 and two side plates 102, wherein the two side plates 102 are symmetrically connected to two sides of the square frame 101 through bolts, and the supporting plate 3 is connected between the two side plates 102.
The plurality of supporting plate pieces 3 are provided with 6 small supporting plates 301 and a large supporting plate 302, 6 arc-shaped grooves 7 which are uniformly distributed are cut on the inner wall of the square frame 101, and the 6 arc-shaped grooves 7 correspond to the small supporting plates 301 one by one.
The small supporting plate 301 comprises a supporting plate bottom 3011 and two supporting plates 3012, the two supporting plates 3012 are movably connected to two sides of the supporting plate bottom 3011, sealing pads are connected to two sides of the supporting plate bottom 3011, and an elastic telescopic rod 11 is arranged between the supporting plate 3012 and the supporting plate bottom 3011.
Receiving agencies includes swinging arms 8, and swinging arms 8 rotates through the round pin axle and connects in the bottom of even board 402, and swinging arms 8 both sides outer wall all is connected with elastic element 9, and elastic element 9 keeps away from the one end of swinging arms 8 and connects in the bottom of even board 402, and the bottom of swinging arms 8 is connected with brush 10, and brush 10 offsets with little layer board 301 activity.
The vacuumizing system comprises a water vapor condenser 12, the water vapor condenser 12 is connected to the outer wall of the drying box 1, the outer wall of the water vapor condenser 12 is connected with a vacuum pump 13, the water vapor condenser 12 is connected with the drying box 1 through a pipeline, the freezing system comprises a refrigerator 14, the refrigerator 14 is connected to the bottom of the drying box 1, the inner wall of the drying box 1 is connected with a plurality of refrigerating pipes 15, and the refrigerating pipes 15 are connected with the refrigerator 14.
When the device is used, liquid materials needing freeze drying are put in from the feed inlet 1011, a large pile of materials firstly fall on the uppermost supporting plate piece 3, then the materials are liquid and fall on the supporting plate pieces 3 of each layer by layer due to the liquidity of the liquid, the materials are quickly placed on the supporting plates of each layer, the cover plate 2 is closed, the operation of a vacuum pumping system and a freezing system is controlled, the materials in the drying box 1 are freeze-dried, the freeze-dried materials are powdery, the operation of the driving source 6 is controlled at the moment, the driving source 6 drives the threaded rod 4 to rotate, the connecting plate 402 which is in threaded connection with the outer side of the connecting plate drives the material receiving mechanism to move, when the swinging rod 8 moves, the elastic elements 9 on the two sides are stretched and contracted, the swinging rod 8 is obliquely placed, the bottom brush 10 is tightly attached to the bottom 3011 of the supporting plate, and the effect of cleaning the powdery materials by the brush 10 is improved, along with the continuation operation of driving source 6, brush 10 offsets with extension board 3012 gradually, make extension board 3012 keep away from the side at the bottom of the layer board 3011, elasticity telescopic link 11 is tensile, likepowder solid material drops on the layer board piece 3 of one deck next, along with the positive reverse rotation drive of driving source 6, until the material is all dropped on the big layer board 302 of bottom, when the material after the freeze-drying needs to be taken out, dismantle two curb plates 102 from "mouth" word frame 101, be convenient for take out fast and place the material in big layer board 302 in, the device can be convenient for get the material fast, staff's intensity of labour is reduced, and then improve production efficiency, reduce the production energy consumption.
Claims (6)
1. The utility model provides a freeze-drying device is used in polypeptide production, includes drying cabinet (1), be provided with evacuation system and refrigerating system in drying cabinet (1), its characterized in that: a feed inlet (1011) is formed in the top of the drying box (1), a cover plate (2) is movably connected in the feed inlet (1011), a plurality of supporting plate parts (3) are connected between the inner walls of the two sides of the drying box (1), the bottoms of the supporting plate parts (3) are connected with heating plates (303), a threaded rod (4) is movably connected above each supporting plate part (3), the outer wall of the threaded rod (4) is in threaded connection with a connecting plate (402), the bottom of the connecting plate (402) is connected with a material receiving mechanism, the outer walls of two adjacent threaded rods (4) are connected with synchronous wheels (401) which are matched with each other, a belt is connected between the synchronous wheels (401) on the same side, the outer wall of the drying box (1) is connected with a supporting seat (5), the outer wall of the supporting seat (5) is connected with a driving source (6), the output end of the driving source (6) penetrates through the drying box (1) and is connected with one of the threaded rods (4).
2. The freeze-drying device for polypeptide production according to claim 1, wherein: the drying box (1) comprises a square frame (101) and two side plates (102), the two side plates (102) are symmetrically connected to the two sides of the square frame (101) through bolts, and the support plate component (3) is connected between the two side plates (102).
3. The freeze-drying device for polypeptide production according to claim 2, wherein: the supporting plate pieces (3) are provided with 6 small supporting plates (301) and a large supporting plate (302), 6 arc-shaped grooves (7) which are uniformly distributed are formed in the inner wall of the square frame (101), and the 6 arc-shaped grooves (7) correspond to the small supporting plates (301) one by one.
4. The freeze-drying device for polypeptide production according to claim 3, wherein: the small supporting plate (301) comprises a supporting plate bottom (3011) and two supporting plates (3012), the supporting plates (3012) are movably connected to two sides of the supporting plate bottom (3011), sealing gaskets are connected to two sides of the supporting plate bottom (3011), and an elastic telescopic rod (11) is arranged between the supporting plate (3012) and the supporting plate bottom (3011).
5. The freeze-drying device for polypeptide production according to claim 4, wherein: receiving agencies includes swinging arms (8), and this swinging arms (8) rotate through the round pin axle and connect in the bottom of linking board (402), swinging arms (8) both sides outer wall all is connected with elastic element (9), the one end that swinging arms (8) were kept away from in elastic element (9) is connected in the bottom of linking board (402), the bottom of swinging arms (8) is connected with brush (10), brush (10) offset with little layer board (301) activity.
6. The freeze-drying device for polypeptide production according to claim 1, wherein: the vacuum pumping system comprises a water vapor condenser (12), the water vapor condenser (12) is connected to the outer wall of the drying box (1), the outer wall of the water vapor condenser (12) is connected with a vacuum pump (13), the water vapor condenser (12) is connected with the drying box (1) through a pipeline, the freezing system comprises a refrigerator (14), the refrigerator (14) is connected to the bottom of the drying box (1), the inner wall of the drying box (1) is connected with a plurality of refrigerating pipes (15), and the refrigerating pipes (15) are connected with the refrigerator (14).
Priority Applications (1)
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CN202121465304.7U CN215260826U (en) | 2021-06-29 | 2021-06-29 | Freeze-drying device is used in polypeptide production |
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CN202121465304.7U CN215260826U (en) | 2021-06-29 | 2021-06-29 | Freeze-drying device is used in polypeptide production |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114923315A (en) * | 2022-03-16 | 2022-08-19 | 浙江大学 | Preparation facilities of graphite alkene aerogel powder |
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2021
- 2021-06-29 CN CN202121465304.7U patent/CN215260826U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114923315A (en) * | 2022-03-16 | 2022-08-19 | 浙江大学 | Preparation facilities of graphite alkene aerogel powder |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A freeze-drying device for peptide production Granted publication date: 20211221 Pledgee: Nanjing Branch of Jiangsu Bank Co.,Ltd. Pledgor: Nanjing Lyon Biotechnology Co.,Ltd. Registration number: Y2024980023471 |