CN215250850U - High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism - Google Patents

High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism Download PDF

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Publication number
CN215250850U
CN215250850U CN202121009790.1U CN202121009790U CN215250850U CN 215250850 U CN215250850 U CN 215250850U CN 202121009790 U CN202121009790 U CN 202121009790U CN 215250850 U CN215250850 U CN 215250850U
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bottle
bacteria
reagent
fixing frame
body portion
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CN202121009790.1U
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钱晓东
邓晓曼
龙文平
钟文娟
刘玉函
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Guangdong sunshine Biotechnology Co.,Ltd.
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Huizhou Sunshine Biotechnology Co ltd
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Abstract

The application provides a quick detect reagent box of bacterium medicine and bacterium detection mechanism of high detection accuracy. The high-detection-precision bacteria drug sensitivity detection kit comprises a support frame and a bacteria culture component. The bacteria culture assembly comprises a fixing frame and a plurality of reagent bottles, the fixing frame is connected with the supporting frame, the reagent bottles are all connected with the fixing frame and are of transparent structures, an opening and a containing groove are formed in each reagent bottle, the opening is communicated with the containing groove, each reagent bottle comprises a bottle body portion and a bottle bottom portion, a first anti-reflection layer is arranged on the inner wall of the bottle body portion, and a second anti-reflection layer is arranged on the outer surface of the bottle body portion. Because dull polish structure has better absorption and diffuse reflection effect to light, when detecting light and jet into and scatter the internal surface of body of the bottle portion from the opening of reagent bottle, first reflection stratum can absorb and absorb light and carry out diffuse reflection with light, can prevent that the reagent bottle inner wall from producing specular reflection's light, and then can avoid the intensity of main light path to receive the influence.

Description

High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism
Technical Field
The utility model relates to a bacteria detection kit technical field especially relates to a quick detect reagent box of bacterium medicine and bacterium detection mechanism of high detection precision.
Background
The bacteria drug sensitivity detection kit with high detection precision is an experimental tool for detecting the drug resistance of bacteria, bacteria and drugs are dripped into a reagent bottle of the detection kit for culture, so that a bacterial group which is acted by the drugs can be obtained, and the drug resistance of the bacteria is detected and researched.
Turbidimetry is a common method of detecting bacterium quantity, through to reagent bottle light irradiation, because the bacterium of different turbidicities is different to the degree of blockking of light, so can be according to the intensity judgement reagent bottle in the bacterium turbidity of the light of passing reagent bottle, however, use turbidimetry to detect the time measuring to the bacterium in the quick detect reagent box of traditional bacterium medicine of high detection precision, the easy outer wall and the inner wall with the reagent bottle of injected light produce the mirror reflection, the light after the reflection will take place the overlap or cause the interference to the main light path with the main light path in the culture solution, and then cause the influence to the intensity of the emergent light of reagent bottle, the testing result that leads to the bacterium turbidity produces great error.
SUMMERY OF THE UTILITY MODEL
The utility model aims at overcoming the weak point among the prior art, provide one kind and can prevent that the reagent bottle from producing specular reflection, can avoid the intensity of main light way to receive the reflected light influence, can improve the quick detect reagent box of bacterium medicine and the bacterium detection mechanism of the high detection precision of the precision that detects.
The purpose of the utility model is realized through the following technical scheme:
a high detection accuracy bacterial drug sensitivity detection kit, comprising:
a support frame;
the bacteria culture assembly comprises a fixing frame and a plurality of reagent bottles, the fixing frame is connected with the supporting frame and is multiple in number, the reagent bottles are all connected with the fixing frame and are of transparent structures, each reagent bottle is provided with an opening and a containing groove, the opening is communicated with the containing groove, each reagent bottle comprises a bottle body portion and a bottle bottom, a first anti-reflection layer is arranged on the inner wall of the bottle body portion, and a second anti-reflection layer is arranged on the outer surface of the bottle body portion.
In one embodiment, the cross-sectional area of the bottom portion decreases from the end of the bottom portion adjacent to the body portion to the end of the bottom portion away from the body portion.
In one embodiment, the bottom of the bottle is of a tapered configuration.
In one embodiment, the supporting frame, the fixing frame and the plurality of reagent bottles are of an integrally formed structure.
In one embodiment, the distance between two adjacent reagent bottles is equal.
In one embodiment, the supporting frame comprises a supporting frame body and a supporting rubber ring, and the supporting rubber ring is connected with one side, far away from the fixed frame, of the supporting frame body.
In one embodiment, the fixing frame comprises a fixing frame body and two holding parts, the reagent bottles are all connected with the fixing frame body, the two holding parts are respectively connected with two sides of the fixing frame body, and the holding parts are provided with anti-skidding structures.
In one embodiment, the anti-slip structure is a silica gel frosted layer.
In one embodiment, the bottle body part is in a strip structure, and the cross-sectional area of the end of the bottle body part far away from the bottle bottom to the end of the bottle body part close to the bottle bottom is gradually reduced.
A bacteria detection mechanism, comprising the bacteria drug sensitive detection kit with high detection precision in any embodiment.
Compared with the prior art, the utility model discloses at least, following advantage has:
1. the inner wall of body portion is provided with first antireflection layer, first antireflection layer specifically is the dull polish structure of body portion internal surface setting, because dull polish structure has better absorption and diffuse reflection effect to light, when detecting light and jet into and scatter the internal surface of body portion from the opening of reagent bottle, first reflection stratum can absorb and absorb light and carry out diffuse reflection with light, can prevent that the reagent bottle inner wall from producing specular reflection's light, and then can avoid the intensity of main light path to receive the influence.
2. Because the surface of body portion is provided with the second antireflection layer, can absorb and diffuse reflection the light of shining at body portion surface, prevent that reagent bottle outer wall from producing specular reflection light, and then avoid the testing result to receive the interference, help improving the precision of testing result.
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In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic diagram illustrating the structure of a bacterial drug-sensitive detection kit with high detection accuracy in an embodiment;
FIG. 2 is a schematic sectional view of the high detection accuracy bacterial drug sensitive detection kit shown in FIG. 1 along line A-A;
FIG. 3 is a schematic enlarged view of a portion of the high-detection-accuracy bacteria drug-sensitive detection kit shown in FIG. 2 along B.
Detailed Description
In order to facilitate understanding of the present invention, the present invention will be described more fully hereinafter with reference to the accompanying drawings. The preferred embodiments of the present invention are shown in the drawings. The invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in FIG. 1, the bacteria drug-sensitive detection kit 10 with high detection accuracy of an embodiment includes a support frame 100 and a bacteria culture assembly 200. The bacteria culture assembly 200 includes a fixing frame 210 and a plurality of reagent bottles 220, the fixing frame 210 is connected to the support frame 100, the plurality of reagent bottles 220 are all connected to the fixing frame 210, the reagent bottles 220 are transparent, as shown in fig. 2, each reagent bottle 220 is provided with an opening 221 and a receiving groove 222, the opening 221 is communicated with the receiving groove 222, each reagent bottle 220 includes a bottle body 223 and a bottle bottom 224, as shown in fig. 3, a first anti-reflection layer 223a is disposed on an inner wall of the bottle body 223, and a second anti-reflection layer 223b is disposed on an outer surface of the bottle body 223.
In this embodiment, the bacteria drug sensitive detection kit 10 with high detection precision includes the support frame 100 and the bacteria culture assembly 200, the support frame 100 is used for supporting the bacteria culture assembly 200, so as to ensure that the bacteria culture assembly 200 can keep a stable state when in use, the bacteria culture assembly 200 includes a fixing frame 210 and a plurality of reagent bottles 220, the fixing frame 210 is connected with the support frame 100, the plurality of reagent bottles 220 are all installed on the fixing frame 210, the fixing frame 210 is used for fixing the reagent bottles 220, so that the reagent bottles 220 can keep a stable state in the bacteria culture process. Each reagent bottle 220 is provided with an opening 221 and a containing groove 222, the opening 221 and the containing groove 222 are communicated with each other, liquid medicine and bacterial liquid can be injected into the containing groove 222 of the reagent bottle 220 through the opening 221, and the containing groove 222 is used for culturing bacteria so as to obtain bacterial colonies acted by the medicine.
Further, each reagent bottle 220 includes a bottle body 223 and a bottle bottom 224, the bottle body 223 is a sidewall of the reagent bottle 220, and the bottle bottom 224 is an end wall of the reagent bottle 220, when performing turbidimetric detection, light enters from the opening 221 of the reagent bottle 220, and the light irradiates along the extending direction of the bottle body and finally passes through the bottle bottom 224 to exit. Further, the inner wall of body portion 223 is provided with first antireflection layer 223a, first antireflection layer 223a specifically is the dull polish structure of body portion 223 internal surface setting, because dull polish structure has better absorption and diffuse reflection effect to the light, when detecting that light jets into and scatters the internal surface of body portion 223 from reagent bottle 220's opening 221, first reflection stratum can absorb and absorb light and carry out diffuse reflection with light, can prevent that reagent bottle 220 inner wall from producing specular reflection's light, and then can avoid the intensity of main light path to receive the influence. Further, the outer surface of body 223 is provided with second antireflection layer 223b, second antireflection layer 223b specifically is the dull polish mechanism that body 223 surface set up, when detecting light scattering to body 223's outer surface, through the specular reflection of body 223 surface, light after the reflection will kick into in the adjacent reagent bottle 220, cause harmful effects to the detection of adjacent reagent bottle 220, because body 223's outer surface is provided with second antireflection layer 223b, can absorb and diffuse the reflection at body 223 surface, prevent that reagent bottle 220 outer wall from producing specular reflection light, and then avoid the testing result to receive the interference, help improving the precision of testing result.
As shown in fig. 2, in one embodiment, the cross-sectional area of the bottle bottom 224 decreases from the end adjacent to the body portion 223 to the end of the bottle bottom 224 away from the body portion 223. In this embodiment, the bottle bottom 224 is the bottommost part of the reagent bottle 220, and the cross-sectional area from the end of the bottle bottom 224 adjacent to the bottle body 223 to the end of the bottle bottom 224 away from the bottle body 223 gradually decreases, that is, the bottle bottom 224 is a conical or spherical structure, so that the inner wall of the bottle bottom 224 can guide the culture solution of the reagent bottle 220, and helps bacteria or drug substances in the culture solution to sink and accumulate at the lowest part of the bottle bottom 224, and in a laboratory for extracting culture solution, the culture solution with high substance concentration can be extracted, so as to facilitate the detection of the culture solution.
In one embodiment, as shown in FIG. 2, the bottle bottom 224 is tapered. In this embodiment, bottle bottom 224 is the bottommost of reagent bottle 220, the cross-sectional area that bottle bottom 224 is close to the one end of body portion 223 to the one end that bottle bottom 224 kept away from body portion 223 reduces gradually, and bottle bottom 224 is the toper structure, the bottle bottom 224 inner wall of toper structure has better guide effect, can be better with bacterium and the drug substance in the culture solution gather, make the material aggregation effect in the culture solution better, carry out the laboratory at the extraction culture solution, help extracting the culture solution of high material concentration, so that to the detection to the culture solution.
As shown in fig. 2, in one embodiment, the supporting frame 100, the fixing frame 210 and the plurality of reagent bottles 220 are integrally formed. In this embodiment, the supporting frame 100, the fixing frame 210 and the plurality of reagent bottles 220 are integrally formed, and specifically, the supporting frame 100, the fixing frame 210 and the plurality of reagent bottles 220 are integrally formed by injection molding into an injection mold, which facilitates the production of the detection kit and improves the production efficiency thereof. Meanwhile, the support frame 100, the fixing frame 210 and the plurality of reagent bottles 220 are of an integrally formed structure, so that the connection strength between the support frame 100 and the fixing frame 210 and between the reagent bottles 220 and the fixing frame 210 can be improved, the reagent bottles 220 can be stably connected to the fixing frame 210, and the stability of the reagent bottles 220 during storage and movement can be improved.
As shown in fig. 1, in one embodiment, the adjacent two reagent bottles 220 are equally spaced. In this embodiment, a plurality of reagent bottles 220 are rectangular array, evenly arrange on mount 210, and the interval between two adjacent reagent bottles 220 equals, and the even arrangement of a plurality of reagent bottles 220 helps conveniently categorised and the sign to reagent bottle 220 with different experimental parameters divides into groups, can be more convenient during the detection obtain with the record experiment result, improve this detect reagent box's operation convenience.
As shown in fig. 2, in one embodiment, the supporting stand 100 includes a supporting stand body 110 and a supporting rubber ring 120, and the supporting rubber ring 120 is connected to a side of the supporting stand body 110 away from the fixing frame 210. In this embodiment, the supporting frame 100 includes a supporting frame body 110 and a supporting rubber ring 120, the supporting frame body 110 is a main supporting structure of the supporting frame 100, and is used for connecting the fixing frame 210 and bearing most of the pressure from the reagent bottles 220 and the fixing frame 210, the supporting rubber ring 120 is connected to one side of the supporting frame body 110 away from the fixing frame 210, in general, the supporting rubber ring 120 is connected to the bottom of the supporting frame 100, the supporting rubber ring 120 is made of plastic material, and has better buffering and damping performance, when the detection kit is moved and placed, the influence of vibration on the reagent bottles 220 can be reduced, and the stability of the reagent bottles 220 on the fixing frame 210 is improved.
As shown in fig. 1, in one embodiment, the fixing frame 210 includes a fixing frame body and two holding portions, the reagent bottles 220 are all connected to the fixing frame body, the two holding portions are respectively connected to two sides of the fixing frame body, and the holding portions are provided with anti-slip structures. In this embodiment, the both sides of mount body are connected with the portion of gripping, and when the operator removed this detect reagent box, the portion of gripping through centre gripping mount body both sides was in order to remove this detect reagent box, and the portion of gripping is provided with anti-skidding structure, and anti-skidding structure can increase the coefficient of friction of the portion of gripping for the operator is difficult for skidding when removing detect reagent box, helps preventing misoperation.
In one embodiment, as shown in fig. 1, the anti-slip structure is a silica frosted layer. In this embodiment, the anti-skidding structure that sets up on the portion of gripping is silica gel frosting, and the roughness on the surface on silica gel frosting is higher for its surperficial coefficient of friction is higher, and difficult slipping when operator's centre gripping portion helps preventing misoperation.
As shown in fig. 2, in one embodiment, the body portion 223 has a strip-shaped structure, and the cross-sectional area of the body portion 223 decreases from the end of the bottle bottom 224 to the end of the body portion 223 adjacent to the bottle bottom 224. In this embodiment, the cross-sectional area of the end of the body portion 223 away from the bottom 224 gradually decreases from the end of the body portion 223 adjacent to the bottom 224, i.e. the cross-sectional area of the opening 221 of the reagent bottle 220 is larger than the cross-sectional area of the portion below the opening 221, so that when the culture solution is added to the reagent bottle 220, the culture solution is prevented from overflowing out of the opening 221 of the reagent bottle 220, and the probability of misoperation is reduced.
The application also provides a bacteria detection mechanism, which comprises the bacteria drug sensitive detection kit 10 with high detection precision in any embodiment. In one embodiment, the bacteria drug sensitive detection kit 10 with high detection precision comprises a support frame 100 and a bacteria culture assembly 200. The bacteria culture assembly 200 comprises a fixing frame 210 and a plurality of reagent bottles 220, the fixing frame 210 is connected with the support frame 100, the plurality of reagent bottles 220 are all connected with the fixing frame 210, the reagent bottles 220 are of a transparent structure, each reagent bottle 220 is provided with an opening 221 and a containing groove 222, the openings 221 are communicated with the containing grooves 222, each reagent bottle 220 comprises a bottle body portion 223 and a bottle bottom portion 224, a first anti-reflection layer 223a is arranged on the inner wall of the bottle body portion 223, and a second anti-reflection layer 223b is arranged on the outer surface of the bottle body portion 223.
In this embodiment, the bacteria drug sensitive detection kit 10 with high detection precision includes the support frame 100 and the bacteria culture assembly 200, the support frame 100 is used for supporting the bacteria culture assembly 200, so as to ensure that the bacteria culture assembly 200 can keep a stable state when in use, the bacteria culture assembly 200 includes a fixing frame 210 and a plurality of reagent bottles 220, the fixing frame 210 is connected with the support frame 100, the plurality of reagent bottles 220 are all installed on the fixing frame 210, the fixing frame 210 is used for fixing the reagent bottles 220, so that the reagent bottles 220 can keep a stable state in the bacteria culture process. Each reagent bottle 220 is provided with an opening 221 and a containing groove 222, the opening 221 and the containing groove 222 are communicated with each other, liquid medicine and bacteria liquid can be injected into the containing groove 222 of the reagent bottle 220 through the opening 221, and the containing groove 222 is used for culturing bacteria so as to obtain bacteria groups acted by the medicine.
Further, each reagent bottle 220 includes a bottle body 223 and a bottle bottom 224, the bottle body 223 is a sidewall of the reagent bottle 220, and the bottle bottom 224 is an end wall of the reagent bottle 220, when performing turbidimetric detection, light enters from the opening 221 of the reagent bottle 220, and the light irradiates along the extending direction of the bottle body and finally passes through the bottle bottom 224 to exit. Further, the inner wall of body portion 223 is provided with first antireflection layer 223a, first antireflection layer 223a specifically is the dull polish structure of body portion 223 internal surface setting, because dull polish structure has better absorption and diffuse reflection effect to the light, when detecting that light jets into and scatters the internal surface of body portion 223 from reagent bottle 220's opening 221, first reflection stratum can absorb and absorb light and carry out diffuse reflection with light, can prevent that reagent bottle 220 inner wall from producing specular reflection's light, and then can avoid the intensity of main light path to receive the influence. Further, the outer surface of body 223 is provided with second antireflection layer 223b, second antireflection layer 223b specifically is the dull polish mechanism that body 223 surface set up, when detecting light scattering to body 223's outer surface, through the specular reflection of body 223 surface, light after the reflection will kick into in the adjacent reagent bottle 220, cause harmful effects to the detection of adjacent reagent bottle 220, because body 223's outer surface is provided with second antireflection layer 223b, can absorb and diffuse the reflection at body 223 surface, prevent that reagent bottle 220 outer wall from producing specular reflection light, and then avoid the testing result to receive the interference, help improving the precision of testing result.
The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims (10)

1. A high detection accuracy's quick detect reagent box of bacterium medicine, its characterized in that includes:
a support frame;
the bacteria culture assembly comprises a fixing frame and a plurality of reagent bottles, the fixing frame is connected with the supporting frame and is multiple in number, the reagent bottles are all connected with the fixing frame and are of transparent structures, each reagent bottle is provided with an opening and a containing groove, the opening is communicated with the containing groove, each reagent bottle comprises a bottle body portion and a bottle bottom, a first anti-reflection layer is arranged on the inner wall of the bottle body portion, and a second anti-reflection layer is arranged on the outer surface of the bottle body portion.
2. The high detection accuracy bacteria susceptibility test kit of claim 1, wherein the cross-sectional area of the bottom portion of the bottle decreases from the end adjacent to the body portion to the end of the bottom portion of the bottle away from the body portion.
3. The high detection accuracy bacteria susceptibility assay kit of claim 2, wherein said bottom of said vial is of a tapered configuration.
4. The high detection accuracy bacteria drug sensitive detection kit of claim 1, wherein the support frame, the fixing frame and the plurality of reagent bottles are an integrally formed structure.
5. The high detection accuracy bacteria drug sensitive detection kit according to claim 1, wherein the distance between two adjacent reagent bottles is equal.
6. The high-detection-precision bacteria drug-sensitive detection kit according to claim 1, wherein the support frame comprises a support frame body and a support rubber ring, and the support rubber ring is connected with one side of the support frame body, which is far away from the fixing frame.
7. The high detection precision bacteria drug sensitivity detection kit according to claim 1, wherein the fixing frame comprises a fixing frame body and two holding parts, the plurality of reagent bottles are all connected with the fixing frame body, the two holding parts are respectively connected with two sides of the fixing frame body, and the holding parts are provided with anti-skidding structures.
8. The high detection accuracy bacteria drug sensitive detection kit of claim 7, wherein the anti-slip structure is a silica frosted layer.
9. The high detection accuracy bacteria susceptibility test kit of claim 1, wherein the body portion is a strip structure, and the cross-sectional area of the body portion decreases from the end of the body portion away from the bottom of the bottle to the end of the body portion adjacent to the bottom of the bottle.
10. A bacteria detection mechanism comprising the bacteria drug sensitive detection kit with high detection accuracy according to any one of claims 1 to 9.
CN202121009790.1U 2021-05-12 2021-05-12 High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism Active CN215250850U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202121009790.1U CN215250850U (en) 2021-05-12 2021-05-12 High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202121009790.1U CN215250850U (en) 2021-05-12 2021-05-12 High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism

Publications (1)

Publication Number Publication Date
CN215250850U true CN215250850U (en) 2021-12-21

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Application Number Title Priority Date Filing Date
CN202121009790.1U Active CN215250850U (en) 2021-05-12 2021-05-12 High-detection-precision bacteria drug sensitivity detection kit and bacteria detection mechanism

Country Status (1)

Country Link
CN (1) CN215250850U (en)

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Address after: 516007 3rd and 4th floors, building 1, factory building, Huangfengling section, LENGSHUIKENG, Huicheng District, Huizhou City, Guangdong Province

Patentee after: Guangdong sunshine Biotechnology Co.,Ltd.

Address before: 516007 3rd and 4th floors, building 1, factory building, Huangfengling section, LENGSHUIKENG, Huicheng District, Huizhou City, Guangdong Province

Patentee before: HUIZHOU SUNSHINE BIOTECHNOLOGY CO.,LTD.