CN215250812U

CN215250812U - Separation and extraction device of bone marrow mesenchymal stem cells

Info

Publication number: CN215250812U
Application number: CN202121749481.8U
Authority: CN
Inventors: 孙浩博
Original assignee: Beijing Bobaiyue Biotechnology Co ltd
Current assignee: Beijing Bobaiyue Biotechnology Co ltd
Priority date: 2021-07-29
Filing date: 2021-07-29
Publication date: 2021-12-21
Anticipated expiration: 2031-07-29

Abstract

The utility model provides a separation extraction element of mesenchymal stem cells relates to medical instrument technical field, including the separator body, the one end and the inside of the separator body are provided with convenient filter equipment, the one end that convenient filter equipment was kept away from to the surface of the separator body is provided with supplementary play liquid device, convenient filter equipment includes filter cylinder, filter cylinder's surface and separator body's inner wall sliding connection, the first ring piece of one end fixedly connected with of filter cylinder, the surface one side fixedly connected with seal ring piece of first ring piece, seal ring groove has been seted up to surface one side of the separator body, filter cylinder's one end is provided with the cock body. The utility model discloses, whole device is through the interact of first round bar, second round bar, spring, circular port, sealing ring piece and sealing ring groove for the filter screen is separable with the separator body, and convenient clean the maintenance has improved the practicality of device.

Description

Separation and extraction device of bone marrow mesenchymal stem cells

Technical Field

The utility model relates to the technical field of medical equipment, especially, relate to a separation and extraction device of marrow mesenchymal stem cells.

Background

In recent years, many studies and researches have been made at home and abroad to explore methods for in vitro separation and culture of mesenchymal stem cells, mainly including methods of cell adherent separation, density gradient centrifugation, cell sorting and the like, and the method has the precondition that bone marrow in a bone marrow cavity needs to be obtained first, and a separation and extraction device is needed in the process.

In the prior art, the existing separation and extraction devices are all in the appearance of a standing tube, and stem cells are often extracted in a standing mode, but a filter screen for filtering broken bones arranged in the separation and extraction devices is often fixedly connected with the inner wall of a separator body, so that the separation and extraction devices are very inconvenient to clean, and the repeated use of the separation and extraction devices is influenced.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the prior art and providing a separation and extraction device of mesenchymal stem cells.

In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides a separation extraction element of mesenchymal stem cell, includes the separator body, the one end and the inside of the separator body are provided with convenient filter equipment, the one end that convenient filter equipment was kept away from to the surface of the separator body is provided with supplementary play liquid device, convenient filter equipment includes the filter cylinder body, the surface of filter cylinder body and the inner wall sliding connection of the separator body, the first ring piece of one end fixedly connected with of filter cylinder body, the sealed ring piece of surface one side fixedly connected with of first ring piece, sealed annular has been seted up to surface one side of the separator body, the one end of filter cylinder body is provided with the cock body.

In a preferred embodiment, a circular groove is formed in one side of the first ring block, a first round rod is fixedly connected to one side of the inner wall of the circular groove, and a second round rod is slidably connected to one end, far away from the circular groove, of the first round rod.

As a preferred embodiment, the outer surface of the first round bar is sleeved with a spring, and two ends of the spring are fixedly connected with the second round bar and the round groove respectively.

As a preferred embodiment, the outer surface of the separator body is fixedly connected with a second ring block close to the pipe orifice, the outer surface of the second ring block is provided with a circular hole, the size and the shape of the inner wall of the circular hole are matched with those of the outer surface of a second round rod, and the inner wall of the filter cylinder body is provided with filter screens at two sides.

As a preferred embodiment, the auxiliary liquid outlet device comprises a threaded plug and a threaded hole, the threaded hole is formed in the bottom end of the separator body, the threaded hole is in threaded connection with the threaded plug, and an operation block is fixedly connected to one end of the threaded plug.

In a preferred embodiment, four anti-slip extension blocks are fixedly connected to the outer surface of the operation block, and the four anti-slip extension blocks are circumferentially arranged on the outer surface of the operation block.

Compared with the prior art, the utility model has the advantages and positive effects that,

1. the utility model discloses in, through convenient filter equipment, when needs clean the filter screen and make things convenient for its secondary to use, inwards press the second round bar this moment, make the second round bar slide at the surface of first round bar, the second round bar slides and can make the spring take place deformation, when second round bar and circular port separate, upwards stimulate the filter cylinder body this moment, make the filter cylinder body drive the inner wall of seal ring piece at the seal ring groove and slide, when seal ring piece and seal ring groove separate, accomplish the dismantlement to the filter cylinder body this moment, will filter the clean back that finishes of cylinder body, install according to above-mentioned principle, whole device is through first round bar, the second round bar, a spring, the circular port, the interact of seal ring piece and seal ring groove, make the filter screen separable with the separator body, convenient clean the maintenance, the practicality of device has been improved.

2. The utility model discloses in, through setting up supplementary play liquid device, after finishing filtering, the tradition gets the liquid mode and topples over it from the inlet on top, can produce like this and rock, make the liquid after the layering mix once more easily, need stew again, it is very inconvenient, when needs are drawed the liquid that filters, rotate anti-skidding extension piece this moment, make anti-skidding extension piece drive the screw plug at screw hole internal rotation, and then come out screw plug from screw hole internal rotation, the liquid of layering can follow the threaded hole and flow out this moment, whole device is through the interact of each subassembly, make liquid need not to topple over, can directly flow from separator body bottom, avoid rocking the influence of production, the practicality of device has been improved.

Drawings

FIG. 1 is a left side view of the present invention, showing a device for separating and extracting mesenchymal stem cells;

FIG. 2 is a right side view of the device for separating and extracting mesenchymal stem cells of the present invention;

fig. 3 is an enlarged view of a portion a in fig. 1 of the device for separating and extracting mesenchymal stem cells according to the present invention;

fig. 4 is an enlarged view of B in fig. 1 of the device for separating and extracting mesenchymal stem cells of the present invention.

Illustration of the drawings:

1. a separator body; 2. a convenient filtering device; 3. an auxiliary liquid outlet device;

21. a filter cylinder; 22. a first ring block; 23. a sealing ring block; 24. sealing the ring groove; 25. a plug body; 26. a circular groove; 27. a first round bar; 28. a second round bar; 29. a spring; 210. a second ring block; 211. a circular hole; 212. a filter screen;

31. a threaded plug; 32. a threaded hole; 33. an operation block; 34. an anti-skid extension block.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Example 1

As shown in fig. 1, fig. 3 and fig. 4, the present invention provides a technical solution: a separation and extraction device of mesenchymal stem cells comprises a separator body 1, a convenient filter device 2 is arranged at one end and inside of the separator body 1, an auxiliary liquid outlet device 3 is arranged at one end, far away from the convenient filter device 2, of the outer surface of the separator body 1, the convenient filter device 2 comprises a filter cylinder 21, the outer surface of the filter cylinder 21 is in sliding connection with the inner wall of the separator body 1, a first ring block 22 is fixedly connected with one end of the filter cylinder 21, a sealing ring block 23 is fixedly connected with one side of the outer surface of the first ring block 22, a sealing ring groove 24 is arranged at one side of the outer surface of the separator body 1, a plug body 25 is arranged at one end of the filter cylinder 21, a circular groove 26 is arranged at one side of the first ring block 22, a first circular rod 27 is fixedly connected with one side of the inner wall of the circular groove 26, a second circular rod 28 is slidably connected with one end, far away from the circular groove 26, and a spring 29 is sleeved on the outer surface of the first circular rod 27, two ends of the spring 29 are respectively fixedly connected with the second round rod 28 and the round groove 26, the outer surface of the separator body 1 close to the pipe orifice is fixedly connected with a second ring block 210, the outer surface of the second ring block 210 is provided with a round hole 211, the size and the shape of the inner wall of the round hole 211 are matched with the size and the shape of the outer surface of the second round rod 28, and the inner wall of the filter cylinder body 21 is provided with two side filter screens 212.

In this embodiment, with the convenient filtering apparatus 2, when the filter screen 212 needs to be cleaned to facilitate secondary use thereof, the second round rod 28 is pressed inward at this time, so that the second round rod 28 slides on the outer surface of the first round rod 27, the second round rod 28 slides to deform the spring 29, when the second round rod 28 is separated from the circular hole 211, the filter cylinder 21 is pulled upward at this time, so that the filter cylinder 21 drives the seal ring block 23 to slide on the inner wall of the seal ring groove 24, when the seal ring block 23 is separated from the seal ring groove 24, the filter cylinder 21 is disassembled at this time, after the filter cylinder 21 is cleaned, the filter cylinder is assembled according to the above principle, the whole apparatus is separated from the separator body 1 through interaction of the first round rod 27, the second round rod 28, the spring 29, the circular hole 211, the seal ring block 23 and the seal ring groove 24, so that the filter screen 212 is separable from the separator body 1, and cleaning and maintenance are convenient, the practicability of the device is improved.

Example 2

As shown in fig. 2, the auxiliary liquid outlet device 3 includes a threaded plug 31 and a threaded hole 32, the threaded hole 32 is provided at the bottom end of the separator body 1, the threaded hole 32 is in threaded connection with the threaded plug 31, one end of the threaded plug 31 is fixedly connected with an operation block 33, four anti-skid extension blocks 34 are fixedly connected to the outer surface of the operation block 33, and the four anti-skid extension blocks 34 are circumferentially arranged on the outer surface of the operation block 33.

In this embodiment, through setting up supplementary play liquid device 3, after finishing filtering, the tradition gets the liquid mode and is emptyd it from the inlet on top, can produce like this and rock, make the liquid after the layering mix once more easily, need to stew again, it is very inconvenient, when needs are drawed the liquid that filters, rotate anti-skidding extension piece 34 this moment, make anti-skidding extension piece 34 drive screw plug 31 at screw hole 32 internal rotation, and then come out screw plug 31 from screw hole 32 internal rotation, the liquid of layering can be followed screw hole 32 outflow this moment, whole device passes through the interact of each subassembly, make liquid need not to be emptyd, can directly flow from separator body 1 bottom, avoid rocking the influence that produces, the practicality of device has been improved.

The working principle of the embodiment is as follows:

when it is desired to clean the filter screen 212 for a second use, as shown in fig. 1-4, the second rod 28 is pressed inwardly, so that the second rod 28 slides on the outer surface of the first rod 27, the sliding of the second rod 28 deforms the spring 29, when the second round rod 28 is separated from the round hole 211, the filter cylinder 21 is pulled upwards, so that the filter cylinder 21 drives the seal ring block 23 to slide on the inner wall of the seal ring groove 24, when the sealing ring block 23 is separated from the sealing ring groove 24, the filter cylinder body 21 is disassembled at the moment, after the filter cylinder body 21 is cleaned, the filter cylinder body is assembled according to the principle, when the filtered liquid needs to be extracted, the anti-skid extension block 34 is rotated at the moment, so that the anti-skid extension block 34 drives the threaded plug 31 to rotate in the threaded hole 32, thereby rotating the threaded plug 31 out of the threaded bore 32 and allowing stratified fluid to flow out of the threaded bore 32.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in other forms, and any person skilled in the art may use the above-mentioned technical contents to change or modify the equivalent embodiment into equivalent changes and apply to other fields, but any simple modification, equivalent change and modification made to the above embodiments according to the technical matters of the present invention will still fall within the protection scope of the technical solution of the present invention.

Claims

1. The utility model provides a separation extraction element of marrow mesenchymal stem cell, includes separator body (1), its characterized in that: the one end and the inside of separator body (1) are provided with convenient filter equipment (2), the one end that convenient filter equipment (2) were kept away from to the surface of separator body (1) is provided with supplementary play liquid device (3), convenient filter equipment (2) are including filtering barrel (21), the surface of filtering barrel (21) and the inner wall sliding connection of separator body (1), the first ring piece (22) of one end fixedly connected with of filtering barrel (21), surface one side fixedly connected with seal ring piece (23) of first ring piece (22), sealed annular (24) have been seted up to surface one side of separator body (1), the one end of filtering barrel body (21) is provided with cock body (25).

2. The device for separating and extracting mesenchymal stem cells according to claim 1, wherein: circular recess (26) have been seted up to one side of first ring piece (22), inner wall one side fixedly connected with first round bar (27) of circular recess (26), the one end sliding connection that circular recess (26) were kept away from in first round bar (27) has second round bar (28).

3. The device for separating and extracting mesenchymal stem cells according to claim 2, wherein: the outer surface cover of first round bar (27) is equipped with spring (29), the both ends of spring (29) respectively with second round bar (28) and circular recess (26) fixed connection.

4. The device for separating and extracting mesenchymal stem cells according to claim 1, wherein: the outer surface of separator body (1) is close to mouth of pipe department fixedly connected with second ring piece (210), circular port (211) have been seted up to the surface of second ring piece (210), the outer surface size and the shape of the inner wall size and the shape of circular port (211) and second round bar (28) are adapted mutually, the inner wall of filtering barrel (21) is provided with both sides filter screen (212).

5. The device for separating and extracting mesenchymal stem cells according to claim 1, wherein: the auxiliary liquid outlet device (3) comprises a threaded plug (31) and a threaded hole (32), the threaded hole (32) is formed in the bottom end of the separator body (1), the threaded hole (32) is in threaded connection with the threaded plug (31), and one end of the threaded plug (31) is fixedly connected with an operation block (33).

6. The device for separating and extracting mesenchymal stem cells according to claim 5, wherein: the outer surface of the operation block (33) is fixedly connected with four anti-skid extension blocks (34), and the four anti-skid extension blocks (34) are arranged on the outer surface of the operation block (33) in a circumferential mode.