CN215143140U

CN215143140U - Reagent pipe belt cleaning device for nucleic acid extraction appearance

Info

Publication number: CN215143140U
Application number: CN202120824911.1U
Authority: CN
Inventors: 于军辉; 杨磊
Original assignee: Beijing Ruiding Technology Service Co ltd
Current assignee: Beijing Ruiding Technology Service Co ltd
Priority date: 2021-04-21
Filing date: 2021-04-21
Publication date: 2021-12-14
Anticipated expiration: 2031-04-21

Abstract

The utility model discloses a nucleic acid draws reagent pipe belt cleaning device for appearance, the power distribution box comprises a box body, top one side of box is provided with the water pump, the opposite side output of water pump is connected and is provided with the aqueduct, and the top and the bottom of aqueduct are provided with outlet pipe and lower outlet pipe respectively, the horizontal fixed drive mechanism that is provided with in middle part of box, drive mechanism's middle part level is provided with locking device, the vertical joint in top middle part of box is provided with the sanitizer and adds the device, the top of box is provided with cleaning device, the bottom of box is provided with the grid board, the bottom of grid board is provided with the water catch bowl. Has the advantages that: through setting up drive mechanism, can realize overturning wantonly to reagent pipe to prevent to appear the remaining problem of washing liquid in the reagent pipe, in addition, add device and cleaning device and utilize the interact of water pump through the sanitizer, can realize fully rinsing the reagent pipe, thereby solve the current problem that wastes time and energy through manual cleaning.

Description

Reagent pipe belt cleaning device for nucleic acid extraction appearance

Technical Field

The utility model relates to a reagent pipe washs technical field, particularly, relates to a reagent pipe belt cleaning device for nucleic acid extraction appearance.

Background

The nucleic acid extractor is a high-tech product for extracting nucleic acid, and has the advantages of high automation degree, high extraction speed, stable result and simple and convenient operation, and the nucleic acid extractor is divided into two types: one type is large-scale automated, commonly referred to as automated liquid workstations; the other kind is small-size automatic nucleic acid extraction appearance, utilize the automatic purification process that draws of supporting reagent of encapsulation, small-size automatic instrument, because instrument equipment and running cost are low, convenient operation obtains more and more application, but wide application in fields such as conventional scientific research, genomics, disease control system, food safety, legal medical expert, current nucleic acid extraction appearance is equipped with special extraction dish, it can hold dozens of groups simultaneously and draw reagent pipes to draw the dish, make extraction efficiency very high, nevertheless after the nucleic acid extraction finishes, the cleaning work of reagent pipe is inconvenient, often manual cleaning, cause very big puzzlement for medical personnel.

Patent No. CN210847559U discloses a reagent tube cleaning device for nucleic acid extraction instrument, it is through using motor drive cleaning brush to wash the reagent tube, replaces artifical washing, and the cleaning performance is good, and the cleaning efficiency is high, but it still has following not enough in the in-service use process: 1. the fixing plate for placing the reagent tubes is fixedly arranged, and the reagent tubes cannot be turned over in the actual use process, so that the reagent tubes are easily left with cleaning liquid residues, and the reagent tubes are not sufficiently cleaned; 2. this patent is fixed reagent pipe through bolt and snap ring, and not only complex operation can't the tight dynamics of accurate control clamp moreover, can cause the phenomenon emergence that reagent pipe presss from both sides brokenly or the reagent pipe landing in the cleaning process.

An effective solution to the problems in the related art has not been proposed yet.

SUMMERY OF THE UTILITY MODEL

To the problem among the correlation technique, the utility model provides a nucleic acid is reagent pipe belt cleaning device for extraction appearance to overcome the above-mentioned technical problem that current correlation technique exists.

Therefore, the utility model discloses a specific technical scheme as follows:

the utility model provides a nucleic acid draws reagent pipe belt cleaning device for appearance, the power distribution box comprises a box body, top one side of box is provided with the water pump, one side connection of water pump is provided with the inlet tube, the opposite side output of water pump is connected and is provided with the aqueduct, the aqueduct runs through the top of box and extends to the interior bottom of box, and the top and the bottom of aqueduct are provided with outlet pipe and lower outlet pipe respectively, the horizontal fixed drive mechanism that is provided with in middle part of box, drive mechanism's middle part level is provided with locking device, the vertical joint in top middle part of box is provided with the sanitizer and adds the device, one side joint far away from the water pump in the top of box is provided with cleaning device, the bottom of box is provided with the grid board, the bottom of grid board is provided with the water catch bowl, the delivery port has been seted up to one side bottom of water catch bowl.

Furthermore, in order to facilitate cleaning, a plurality of reagent tubes are clamped inside the locking device.

Further, in order to ensure the horizontal movement and the stability of installation of the reagent tube, the transmission mechanism comprises a threaded rod which is transversely arranged, two ends of the threaded rod are respectively sleeved with an installation block, the side surface of the installation block is fixedly connected with the inner wall of the box body, a first guide rod and a second guide rod are respectively arranged between two sides of the two groups of installation blocks in a penetrating way, a moving block is sleeved outside the middle part of the threaded rod, a first guide rod and a second guide rod are respectively arranged on two sides of the moving block in a penetrating way, a worm is sleeved in the middle part of the second guide rod and positioned inside the moving block, a baffle is fixedly arranged at the top end of the moving block, a rotating shaft is longitudinally arranged in a penetrating way in the middle part of the baffle, a worm wheel meshed with the worm is sleeved outside the rotating shaft and positioned inside the baffle, one end of the rotating shaft, far away from the baffle, is horizontally provided with a locking device, one end of the threaded rod is provided with a first motor, and one end of the second guide rod, far away from the first motor, the first motor and the second motor are fixedly connected with the middle part of the mounting block through mounting seats.

Furthermore, in order to ensure that the worm can move left and right on the second guide rod and cannot turn over actively, guide grooves are longitudinally formed in the two sides of the second guide rod, two groups of guide blocks matched with the guide grooves are arranged on the inner side of the worm, and the worm is movably clamped inside the moving block.

Further, guarantee the stability that reagent pipe pressed from both sides the dress in order to realize the quick installation of reagent pipe, locking device includes the casing, the outside of casing and the terminal surface fixed connection of pivot, the inside of casing evenly is provided with the tight piece of the clamp of a plurality of groups relative arrangement, and reagent pipe joint is between two sets of tight pieces of clamp, the one side top and the bottom of pressing from both sides the mutual keeping away from of tight piece all overlap and are equipped with the sleeve, the sleeve is kept away from the inner wall fixed connection who presss from both sides one side of tight piece and casing, and telescopic inside is provided with the spring, a plurality of horn mouths have evenly been seted up to the bottom of casing.

Further, in order to realize that the reagent tube can be installed under the condition that the reagent tube does not need to be completely aligned, the top of the clamping block is of a V-shaped opening structure, and the opening of the bell mouth is gradually reduced in the direction away from the clamping block.

Furthermore, in order to realize automatic control, a controller is arranged on one side of the top of the box body, and the controller is electrically connected with the water pump, the motor I, the motor II, the cleaning agent adding device and the cleaning device respectively.

The utility model has the advantages that:

(1) through setting up drive mechanism, can utilize mutually supporting of worm gear to realize overturning wantonly to reagent pipe to the remaining problem of washing liquid appears in preventing the reagent pipe, and the auto-lock can be realized to worm gear's intermeshing moreover, thereby guarantees the stability of reagent pipe installation, in addition, through the interaction of sanitizer interpolation device and cleaning device and utilization water pump, can realize fully wasing the reagent pipe, thereby solve current problem that wastes time and energy through manual cleaning.

(2) Through setting up locking device, can utilize and press from both sides tight piece and fix the reagent pipe, utilize the elasticity of spring, can realize that the quick installation of reagent pipe guarantees that the reagent pipe presss from both sides the stability of dress, in addition, sets up to the V-arrangement structure through the top that will press from both sides tight piece, can realize also installing the reagent pipe under the condition that need not aim at completely to installation effectiveness has been improved.

(3) Through setting up grid plate and water catch bowl, can realize effectively retrieving and unified the emission clean sewage to prevent that the sanitizer from causing the pollution to the environment.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a sectional view of a cleaning device for a reagent tube for a nucleic acid isolation instrument according to an embodiment of the present invention;

FIG. 2 is an isometric view of a transmission mechanism in a reagent tube cleaning device for a nucleic acid extracting apparatus according to an embodiment of the present invention;

FIG. 3 is a sectional view of a worm in a cleaning device for a reagent vessel for a nucleic acid isolation apparatus according to an embodiment of the present invention;

FIG. 4 is an isometric view of a housing in a reagent tube cleaning device for a nucleic acid extractor in accordance with an embodiment of the present invention;

FIG. 5 is a sectional view of a locking device in a cleaning device for a reagent tube for a nucleic acid isolation apparatus according to an embodiment of the present invention;

fig. 6 is an axonometric view of a clamping block in a reagent tube cleaning device for a nucleic acid extractor according to an embodiment of the present invention.

In the figure:

1. a box body; 2. a water pump; 3. a water inlet pipe; 4. a water conduit; 5. an upper water outlet pipe; 6. a lower water outlet pipe; 7. a transmission mechanism; 701. a threaded rod; 702. mounting blocks; 703. a first guide rod; 704. a second guide rod; 70401. a guide groove; 705. a moving block; 706. a worm; 70601. a guide block; 707. a baffle plate; 708. a rotating shaft; 709. a worm gear; 710. a first motor; 711. a second motor; 8. a locking device; 801. a housing; 802. a clamping block; 803. a sleeve; 804. a spring; 805. a bell mouth; 9. a detergent adding device; 10. a cleaning device; 11. a grid plate; 12. a water collection tank; 13. a water outlet; 14. a reagent tube; 15. and a controller.

Detailed Description

For further explanation of the embodiments, the drawings are provided as part of the disclosure and serve primarily to illustrate the embodiments and, together with the description, to explain the principles of operation of the embodiments, and to provide further explanation of the invention and advantages thereof, it will be understood by those skilled in the art that various other embodiments and advantages of the invention are possible, and that elements in the drawings are not to scale and that like reference numerals are generally used to designate like elements.

According to the utility model discloses an embodiment provides a nucleic acid draws reagent pipe belt cleaning device for appearance.

Referring now to the drawings and the detailed description, as shown in fig. 1-6, the device for cleaning a reagent tube for a nucleic acid extracting apparatus according to an embodiment of the present invention comprises a box 1, a water pump 2 is disposed on one side of the top end of the box 1, a water inlet tube 3 is connected to one side of the water pump 2, a water guide tube 4 is connected to the other side output end of the water pump 2, the water guide tube 4 penetrates the top end of the box 1 and extends to the inner bottom of the box 1, an upper water outlet tube 5 and a lower water outlet tube 6 are disposed on the top and bottom of the water guide tube 4 respectively, a transmission mechanism 7 is transversely fixed in the middle of the box 1, a locking device 8 is horizontally disposed in the middle of the transmission mechanism 7, a detergent adding device 9 is vertically clamped in the middle of the top end of the box 1, a cleaning device 10 is clamped on one side of the top end of the box 1 away from the water pump 2, a grid plate 11 is disposed on the bottom end of the box 1, the bottom of grid plate 11 is provided with water catch bowl 12, and water outlet 13 has been seted up to one side bottom of water catch bowl 12.

By means of above-mentioned scheme, through setting up drive mechanism 7, can realize overturning wantonly reagent pipe 14 to the remaining problem of washing liquid appears in preventing reagent pipe 14, in addition, add device 9 and cleaning device 10 and utilize water pump 2's interact through the sanitizer, can realize fully rinsing reagent pipe 14, thereby solve current problem that wastes time and energy through manual cleaning.

In one embodiment, the internal clamping of the locking device 8 is provided with a number of reagent vessels 14, so that cleaning is facilitated.

In one embodiment, the transmission mechanism 7 includes a threaded rod 701 arranged transversely, both ends of the threaded rod 701 are sleeved with mounting blocks 702, the side surfaces of the mounting blocks 702 are fixedly connected with the inner wall of the box body 1, a first guide rod 703 and a second guide rod 704 are respectively arranged between both sides of two sets of the mounting blocks 702 in a penetrating manner, a moving block 705 is sleeved on the outer side of the middle portion of the threaded rod 701, both sides of the moving block 705 are respectively provided with the first guide rod 703 and the second guide rod 704 in a penetrating manner, a worm 706 is sleeved on the middle portion of the second guide rod 704 and positioned inside the moving block 705, a baffle 707 is fixedly arranged at the top end of the moving block 705, a rotating shaft 708 is longitudinally arranged in a penetrating manner in the middle portion of the baffle 707, a worm wheel 709 meshed with the worm 706 is sleeved on the outer side of the rotating shaft 708 and positioned inside the baffle 707, a locking device 8 is horizontally arranged at one end of the rotating shaft 708 far away from the baffle 707, a first motor 710 is arranged at one end of the second guide rod 704, the first motor 710 and the second motor 711 are fixedly connected with the middle of the mounting block 702 through the mounting seat, the reagent tube 14 is turned over randomly by utilizing the mutual matching of the worm wheel 709 and the worm 706, and the self-locking can be realized by the mutual meshing of the worm wheel 709 and the worm 706, so that the mounting stability of the reagent tube 14 is ensured.

In one embodiment, two sides of the second guide rod 704 are longitudinally provided with guide grooves 70401, two groups of guide blocks 70601 matched with the guide grooves 70401 are arranged on the inner side of the worm 706, and the worm 706 is movably clamped inside the moving block 705, so that the worm 706 can move left and right on the second guide rod 704 and cannot actively turn over.

In one embodiment, the locking device 8 includes a housing 801, the outer side of the housing 801 is fixedly connected to the end surface of the rotating shaft 708, a plurality of sets of clamping blocks 802 arranged oppositely are uniformly disposed inside the housing 801, the reagent tube 14 is clamped between the two sets of clamping blocks 802, sleeves 803 are respectively sleeved on the top and the bottom of the side, away from each other, of the clamping blocks 802, one side, away from the clamping blocks 802, of each sleeve 803 is fixedly connected to the inner wall of the housing 801, springs 804 are disposed inside the sleeves 803, and a plurality of bell mouths 805 are uniformly disposed at the bottom of the housing 801, so that the reagent tube 14 can be fixed by the clamping blocks 802, and the reagent tube 14 can be quickly mounted and the clamping stability of the reagent tube 14 can be ensured by the elasticity of the springs 804.

In one embodiment, the top of clamping block 802 is a V-shaped opening structure, and flare 805 is gradually reduced in opening in a direction away from clamping block 802, so that reagent tube 14 can be installed without perfect alignment.

In one embodiment, a controller 15 is disposed on one side of the top of the tank 1, and the controller 15 is electrically connected to the water pump 2, the first motor 710, the second motor 711, the detergent adding device 9 and the cleaning device 10, so that automatic control can be realized.

For the convenience of understanding the technical solution of the present invention, the following detailed description is made on the working principle or the operation mode of the present invention in the practical process.

In practical application, a control program is input in the controller 15 in advance, a medical staff manually puts the reagent tube 14 between the two groups of clamping blocks 802, quick clamping is realized by the action of the spring 804, the first motor 710 is started, the first motor 710 drives the threaded rod 701 to rotate, so that the moving block 705 drives the locking device 8 and the reagent tube 14 thereon to horizontally move leftwards along the first guide rod 703 and the second guide rod 704, when the reagent tube 14 runs to the position right below the upper water outlet pipe 5 and the detergent adding device 9, water and detergent are respectively added to the reagent tube 14, when the reagent tube 14 runs to the position right below the cleaning device 10, the cleaning brush on the cleaning device 10 moves upwards and downwards to fully clean the reagent tube 14 (the specific structures and working principles of the detergent adding device 9 and the cleaning device 10 are the prior art, and the description is not provided herein), and the first motor 710 reversely rotates after cleaning is completed, the reagent tube 14 starts to move rightwards, at the moment, the motor II 711 is started, the motor II 711 drives the guide rod II 704 to rotate, the guide rod II 704 drives the worm 706 to rotate, the worm 706 drives the worm wheel 709 to rotate, the worm wheel 709 drives the shell 801 to turn over through the rotating shaft 708, so that residual liquid in the reagent tube 14 is poured out, when the reagent tube 14 runs right above the lower water outlet tube 6, the lower water outlet tube 6 can fully clean the inside of the reagent tube 14 again, after the cleaning is finished, the motor II 711 turns over to reset the reagent tube 14, and therefore the cleaning process of the whole reagent tube 14 is finished.

In conclusion, with the aid of the above technical scheme of the utility model, through setting up drive mechanism 7, can utilize mutually supporting of worm wheel 709 worm 706 to realize overturning wantonly reagent pipe 14, thereby prevent to appear the remaining problem of washing liquid in the reagent pipe 14, and the auto-lock can be realized to worm wheel 709 worm 706's intermeshing, thereby guarantee the stability of reagent pipe 14 installation, in addition, add device 9 and cleaning device 10 and utilize water pump 2's interact through the sanitizer, can realize fully wasing reagent pipe 14, thereby solve the current problem that wastes time and energy through manual cleaning.

In addition, through setting up locking device 8, can utilize the tight piece 802 of clamp to fix reagent pipe 14, utilize the elasticity of spring 804, can realize the stability that reagent pipe 14 presss from both sides the dress is guaranteed in quick installation of reagent pipe 14, in addition, through setting up the top of pressing from both sides tight piece 802 to the V-arrangement structure, can realize also installing reagent pipe 14 under the condition that need not align completely to the installation effectiveness has been improved.

In addition, through setting up grid plate 11 and water catch bowl 12, can realize effectively retrieving and discharging in unison the clean sewage to prevent that the sanitizer from causing the pollution to the environment.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations.

The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The reagent tube cleaning device for the nucleic acid extraction instrument is characterized by comprising a box body (1), wherein a water pump (2) is arranged on one side of the top end of the box body (1), a water inlet pipe (3) is connected and arranged on one side of the water pump (2), a water guide pipe (4) is connected and arranged on the other side output end of the water pump (2), the water guide pipe (4) penetrates through the top end of the box body (1) and extends to the inner bottom of the box body (1), an upper water outlet pipe (5) and a lower water outlet pipe (6) are respectively arranged at the top and the bottom of the water guide pipe (4), a transmission mechanism (7) is transversely and fixedly arranged in the middle of the box body (1), a locking device (8) is horizontally arranged in the middle of the transmission mechanism (7), a detergent adding device (9) is vertically clamped and arranged in the middle of the top end of the box body (1), and a cleaning device (10) is clamped and arranged on one side, far away from the water pump (2), on the top end of the box body (1), the bottom of box (1) is provided with grid board (11), the bottom of grid board (11) is provided with water catch bowl (12), delivery port (13) have been seted up to one side bottom of water catch bowl (12).

2. The device for cleaning the reagent tube for the nucleic acid extractor according to claim 1, wherein the locking device (8) is provided with a plurality of reagent tubes (14) in a clamping manner inside.

3. The cleaning device for the reagent tube for the nucleic acid extractor as claimed in claim 2, wherein the transmission mechanism (7) comprises a threaded rod (701) which is transversely arranged, both ends of the threaded rod (701) are sleeved with mounting blocks (702), the side surfaces of the mounting blocks (702) are fixedly connected with the inner wall of the box body (1), a first guide rod (703) and a second guide rod (704) are respectively arranged between two sides of two sets of the mounting blocks (702) in a penetrating manner, a moving block (705) is sleeved outside the middle of the threaded rod (701), both sides of the moving block (705) are respectively provided with the first guide rod (703) and the second guide rod (704) in a penetrating manner, a worm (706) is sleeved in the middle of the second guide rod (704) and positioned inside the moving block (705), and a baffle (707) is fixedly arranged at the top end of the moving block (705), the middle part of baffle (707) vertically runs through and is provided with pivot (708), the outside of pivot (708) just is located the inside cover of baffle (707) is equipped with worm wheel (709) that worm (706) engaged with, the one end level that baffle (707) was kept away from in pivot (708) is provided with locking device (8), the one end of threaded rod (701) is provided with motor one (710), the one end that motor one (710) was kept away from in guide arm two (704) is provided with motor two (711), motor one (710) and motor two (711) all through the mount pad with the middle part fixed connection of installation piece (702).

4. The cleaning device for the reagent tube for the nucleic acid extractor as claimed in claim 3, wherein two sides of the second guide rod (704) are longitudinally provided with guide grooves (70401), two sets of guide blocks (70601) matched with the guide grooves (70401) are arranged on the inner side of the worm (706), and the worm (706) is movably clamped inside the moving block (705).

5. The device for cleaning the reagent tube for the nucleic acid extractor according to claim 3, wherein the locking device (8) comprises a housing (801), the outer side of the housing (801) is fixedly connected with the end face of the rotating shaft (708), a plurality of sets of clamping blocks (802) which are arranged oppositely are uniformly arranged in the housing (801), the reagent tube (14) is clamped between the two sets of clamping blocks (802), sleeves (803) are sleeved on the top and the bottom of the side, away from each other, of the clamping blocks (802), one side, away from the clamping blocks (802), of the sleeves (803) is fixedly connected with the inner wall of the housing (801), springs (804) are arranged in the sleeves (803), and a plurality of bell mouths (805) are uniformly arranged at the bottom of the housing (801).

6. The device for washing a reagent tube for a nucleic acid isolation instrument according to claim 5, wherein the top of the clamping block (802) has a V-shaped opening structure, and the opening of the bell mouth (805) is gradually reduced in a direction away from the clamping block (802).

7. The device for washing the reagent tube for the nucleic acid extractor according to claim 3, wherein a controller (15) is disposed on one side of the top of the case (1), and the controller (15) is electrically connected to the water pump (2), the motor I (710), the motor II (711), the detergent adding device (9), and the cleaning device (10), respectively.