CN215103201U

CN215103201U - Kit for nanometer magnetic bead separation system

Info

Publication number: CN215103201U
Application number: CN202023282086.1U
Authority: CN
Inventors: 赵晰; 张森; 杜红江
Original assignee: Ey Medical Technology Changzhou Co ltd
Current assignee: Ey Medical Technology Changzhou Co ltd
Priority date: 2020-12-31
Filing date: 2020-12-31
Publication date: 2021-12-10
Anticipated expiration: 2030-12-31

Abstract

The utility model relates to a kit that nanometer magnetic bead piece-rate system used, including a plurality of reagent box pipes that are the matrix arrangement and the outer loop cover that surrounds this matrix arrangement's reagent box pipe, through division board fixed connection between the reagent box pipe of outer loop cover and this matrix arrangement, the reagent box pipe is square pipe, and a circular trompil has been seted up to its inner chamber bottom, and the circular trompil of ring has the direction limit post, has slope nest mouth on the direction limit post, and the tight circular trompil is pasted to the lower of slope nest mouth. The positioning and stirring effect of the stirring rod is realized through the arrangement of the round hole, and a probing space is provided by virtue of the square pipe, so that stirring is facilitated and the stirring rod stretches into and out; through the nest mouth of direction limit post cooperation slope, when the extract by the stirring sputter appearing, guarantee to seal the effect through circular trompil, through the setting of the nest mouth of slope, when partial extract promotes, accomodate it along the direction of the nest mouth of slope, accomodate respond well, can be fine place sputter.

Description

Kit for nanometer magnetic bead separation system

Technical Field

The utility model relates to a kit particularly, relates to a kit that nanometer magnetic bead piece-rate system used.

Background

Chinese patent application No. CN201922311098.3 discloses a nucleic acid extraction and purification kit of silicon substrate magnetic beads, and particularly relates to the field of kits, and the kit comprises a reagent frame box, wherein a plurality of fixing mechanisms are fixedly arranged in the inner cavity of the reagent frame box; the fixing mechanism comprises a fixed reagent tube, the fixed reagent tube is fixedly installed in an inner cavity of the reagent frame box, a plurality of limiting clamping plates are fixedly installed on the inner cavity side wall of the fixed reagent tube, limiting pressing plates are fixedly installed on the inner cavity of the limiting clamping plates, the limiting pressing plates are fixedly installed on the inner cavity side wall of the reagent frame box, and the limiting clamping plates and the limiting pressing plates are arranged in a one-to-one correspondence mode. The utility model discloses a set up fixed establishment, utilize the frame of placeeing of the inside setting of spacing frame lid to fix a plurality of reagent pipes simultaneously, solved the problem of the fixed reagent pipe of being not convenient for among the prior art.

Such a kit has a disadvantage in that the stirring effect of the kit is general when stirring, and the splashing of the liquid is generally caused when stirring because each stirring space is relatively independent.

Therefore, it is necessary to provide a reagent cartridge that can prevent liquid from splashing to some extent.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a prevent the kit of liquid splash to a certain extent to solve above-mentioned problem.

In order to realize the above-mentioned purpose, the embodiment of the utility model provides a kit that nanometer magnetic bead piece-rate system used, include a plurality of reagent box pipes that are the matrix arrangement and surround this matrix arrangement the outer loop cover of reagent box pipe, outer loop cover and this matrix arrangement pass through division board fixed connection between the reagent box pipe, the reagent box pipe is square pipe, and a circular trompil has been seted up to its inner chamber bottom, and the ring circular trompil has a direction limit post, it caves in mouthful to have the slope on the direction limit post, the lowest of mouthful is hugged in the slope pastes tightly circular trompil, adjacent two the edge of direction limit post joins each other.

Preferably, the bottom of the circular opening forms a bearing cavity which is narrowed by width, and the side wall of the bearing cavity is rounded and forms an extrusion arc which converges to the center of the circular opening.

Preferably, the isolation plate is in a right-angle trapezoid shape, the short upper bottom surface of the isolation plate is fixedly connected with the reagent box tubes arranged in the matrix, and the long upper bottom surface of the isolation plate is fixedly connected with the inner wall of the outer ring cover.

Preferably, a transition plate is integrally arranged at the short upper bottom surface of the isolation plate, the long edge of the transition plate is matched with the outer wall of the reagent box tubes arranged in the matrix, and the axial length of the long upper bottom surface is matched with the axial length of the inner wall of the outer ring cover.

Preferably, a step part is integrally arranged around the outer ring cover, the step part comprises a horizontal ring and a vertical ring which are integrally arranged, the inner wall of the vertical ring is inclined, and the inclination range of the inner wall of the vertical ring is 0-15 degrees.

Preferably, a clamping notch is formed in the outer ring cover from the vertical ring and the horizontal ring in sequence, and the side wall of the clamping notch is inclined to form a table body.

Preferably, a side edge is guided at one corner of the outer ring cover, and the upper end face of the outer ring cover is marked with a horizontal and vertical number.

The embodiment of the utility model provides a following beneficial effect has:

1. the original reagent box tube is matched with the outer ring cover and the isolation plate, so that the whole nucleic acid is loaded and stored, the structure is simple, and the storage effect is good;

2. the positioning and stirring effect of the stirring rod is realized through the arrangement of the round hole, and a probing space is provided by virtue of the square pipe, so that stirring is facilitated and the stirring rod stretches into and out;

3. through the nest mouth of direction limit post cooperation slope, when the extract by the stirring sputter appearing, guarantee to seal the effect through circular trompil, through the setting of the nest mouth of slope, when partial extract promotes, accomodate it along the direction of the nest mouth of slope, accomodate respond well, can be fine place sputter.

Drawings

The present invention will be further explained with reference to the drawings and examples.

Fig. 1 is a schematic back structural diagram of a kit for a nano magnetic bead separation system according to an embodiment of the present invention;

fig. 2 is a front view of a kit for a nano magnetic bead separation system according to an embodiment of the present invention;

fig. 3 is a schematic front structural diagram of a kit for a nanobead separation system according to an embodiment of the present invention;

fig. 4 shows a schematic structural diagram of a reagent kit tube provided by an embodiment of the present invention.

In the figure:

a reagent box tube 1 with a circular opening 101;

a guide jamb 102, angled pocket 1021;

a bearing cavity 103, an extrusion arc 104 and a transverse and longitudinal number 105;

the outer ring cover 2, the vertical ring 201, the horizontal ring 202, the clamping notch 203 and the edge 204;

the partition board 3, the transition board 301, the long upper bottom surface 302 and the short upper bottom surface 303.

Detailed Description

The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic drawings and illustrate the basic structure of the present invention only in a schematic manner, and thus show only the components related to the present invention.

As shown in fig. 1 to 4, a kit for a magnetic nanobead separation system comprises a plurality of reagent cartridge tubes 1 arranged in a matrix and an outer ring cover 2 surrounding the reagent cartridge tubes 1 arranged in the matrix, wherein the matrix arrangement means that a plurality of reagent cartridge tubes are arranged in a horizontal row and a plurality of reagent cartridge tubes are arranged in a vertical row, which form a matrix arrangement, and the side walls of the reagent cartridge tubes 1 in each matrix arrangement are attached to each other two by two to form a whole. The outer ring cover 2 is fixedly connected with the reagent box tubes 1 arranged in the matrix through the partition board 3, the connection position of the partition board 3 is located at the joint of the two reagent box tubes 1, so that the overall connection strength of the reagent box tubes is further enhanced, the reagent box tubes 1 are square tubes, and the square tubes are adopted, so that the connection between the reagent box tubes and the reagent box tubes is facilitated, and the whole reagent box tubes can be stably and well connected.

The bottom of the inner cavity of the extracting device is provided with a circular opening 101, the circular opening 101 is provided with a guide side column 102, the guide side column 102 is provided with an inclined socket 1021, the lowest part of the inclined socket 1021 is attached to the circular opening 101, the edges of two adjacent guide side columns 102 are mutually jointed, and the inclined socket 1021 is arranged to be convenient for slowly guiding the sputtered extracting solution to the circular opening 101.

The original reagent box tube 1 is matched with the outer ring cover 2 and the isolation plate 3, so that the whole nucleic acid is loaded and stored, the structure is simple, and the storage effect is good; the positioning and stirring effect of the stirring rod is realized through the arrangement of the round opening 101, and a probing space is provided by virtue of the square pipe, so that stirring is facilitated and the stirring rod stretches into and stretches out; through the cooperation of direction side post 102 slope nest mouth 1021, when the extract when appearing sputtering through the stirring, guarantee through circular trompil 101 and seal the effect, through the setting of slope nest mouth 1021, when partial extract promotes, accomodate it along slope nest mouth 1021 direction, accomodate effectually, can be fine place sputter.

In some embodiments, the bottom of the circular opening 101 forms a bearing cavity 103 with a tapered shape, which is a bearing cavity 103 with a narrow width, and the bearing cavity 103 is integrally formed with the side wall of the circular opening 101, and the side wall of the bearing cavity 103 is rounded and forms a pressing arc 104 converging toward the center of the circular opening 101. Wherein, the setting of extrusion arc 104 has compressed its holistic stirring space to extrusion when further aggravating the stirring, thereby guarantee the stirring and mix the effect.

In some embodiments, the isolation plate 3 has a right-angle trapezoid shape, the short upper bottom surface 303 of the isolation plate 3 is fixedly connected with the reagent box tubes 1 arranged in the matrix, and the long upper bottom surface 302 of the isolation plate 3 is fixedly connected with the inner wall of the outer ring cover 2. Wherein, division board 3 and this be the reagent box pipe 1 intercombination of matrix arrangement integrative, guaranteed holistic intensity, secondly, because division board 3 is right angle trapezoidal form, the side of its slope is convenient for further strengthen the support intensity of division board 3 self.

In some embodiments, a transition plate 301 is integrally disposed at the short upper bottom surface 303 of the isolation plate 3, the long side of the transition plate 301 is adapted to the outer wall of the reagent kit tubes 1 arranged in the matrix, and the axial length of the long upper bottom surface 302 is adapted to the axial length of the inner wall of the outer ring cover 2. Wherein, through the setting of transition plate 301, and the setting of its height matches with this outer wall each other, guarantees its holistic complete connection, through the mutual matching of long upper bottom surface 302 and the inner wall of outer ring cover 2, further guarantees its holistic complete connection.

In some embodiments, a step is integrally formed around the outer ring housing 2, the step comprises an integrally formed horizontal ring 202 and a vertical ring 201, the inner wall of the vertical ring 201 is inclined, wherein the inner wall of the vertical ring 201 is inclined in the range of 0 ° -15 °. The inclined inner wall of the vertical ring 201 is convenient for guiding insertion, the inclination degree of the inner wall is set to be 0-15 degrees, and good transition effect and installation effect are guaranteed.

In some embodiments, a clamping notch 203 is formed in the outer ring cover 2 sequentially from the vertical ring 201, the horizontal ring 202, and the side wall of the clamping notch 203 is inclined to form a table body. The notch 203 is arranged to facilitate clamping and positioning of the whole reagent kit, and transition insertion is facilitated through the platform body formed by inclination.

In some embodiments, a corner of the outer ring cover 2 is guided with a rim 204, and a horizontal and vertical number 105 is marked on the upper end face of the outer ring cover 2. The arrangement of the transverse and longitudinal numbers 105 is convenient for observation and positioning.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides a kit that nanometer magnetic bead piece-rate system used, its characterized in that includes a plurality of reagent box pipes that are the matrix arrangement and surrounds this matrix arrangement the outer loop cover of reagent box pipe, outer loop cover and this matrix arrangement pass through division board fixed connection between the reagent box pipe, the reagent box pipe is square pipe, and a circular trompil has been seted up to its inner chamber bottom, encircles circular trompil has a direction limit post, it has the slope to nest the mouth to lead on the limit post, the slope is sat the lowest of mouth and is pasted tightly circular trompil, adjacent two the edge of direction limit post joins each other.

2. The kit for a nanobead separation system of claim 1, wherein the bottom of the circular opening forms a narrow and wide support chamber, the side walls of the support chamber are rounded and form an arc of pressure converging toward the center of the circular opening.

3. The kit for a nanobead separation system of claim 2, wherein the isolation plate has a right-angled trapezoid shape, the short upper bottom surface of the isolation plate is fixedly connected to the cartridge tubes arranged in the matrix, and the long upper bottom surface of the isolation plate is fixedly connected to the inner wall of the outer ring housing.

4. A kit for a nanobead separation system according to claim 3, wherein a transition plate is integrally provided at the short upper bottom surface of the isolation plate, the long side of the transition plate is fitted to the outer wall of the cartridge tubes arranged in the matrix, and the axial length of the long upper bottom surface is fitted to the axial length of the inner wall of the outer ring cover.

5. The kit for a nanobead separation system of claim 4, wherein a stepped portion is integrally formed around the outer annular cover, the stepped portion comprising a horizontal ring and a vertical ring integrally formed, the vertical ring having an inner wall inclined, wherein the inner wall of the vertical ring is inclined in the range of 0 ° to 15 °.

6. The kit for a magnetic nanobead separation system of claim 5, wherein a notch is formed on the outer ring cover from the vertical ring, the horizontal ring to the outer ring in sequence, and the sidewall of the notch is inclined to form a platform.

7. The kit for a nanobead separation system of claim 6, wherein a corner of the outer ring housing has a rim, and the upper end surface of the outer ring housing is marked with horizontal and vertical numbers.