CN215080847U

CN215080847U - Bacterial cellulose micro-current dressing

Info

Publication number: CN215080847U
Application number: CN202023348325.9U
Authority: CN
Inventors: 徐祥华; 秦建新; 冯永良
Original assignee: Suzhou Department Of Medical Technology Development Co ltd Han
Current assignee: Suzhou Department Of Medical Technology Development Co ltd Han
Priority date: 2020-12-31
Filing date: 2020-12-31
Publication date: 2021-12-10
Anticipated expiration: 2030-12-31

Abstract

A bacterial cellulose micro-current dressing belongs to the technical field of medical dressings. The substrate comprises a bacterial cellulose substrate and is characterized in that zinc dots and silver dots which are raised above the surface of the bacterial cellulose substrate are combined on one side surface of the bacterial cellulose substrate in a spaced state, and the zinc dots and the silver dots are in a spaced relationship with each other. The advantages are that: the zinc points and the silver points which are protruded from the surface of the bacterial cellulose substrate are combined on the surface of one side of the bacterial cellulose substrate at intervals, so that the combination of the zinc points and the silver points with the bacterial cellulose substrate is realized, the requirements of generating a galvanic cell and releasing micro-current by oxidation-reduction reaction are satisfied when the bacterial cellulose substrate is used, good electrical stimulation is favorably embodied to promote wound healing, and excellent antibacterial property is embodied.

Description

Bacterial cellulose micro-current dressing

Technical Field

The utility model belongs to the technical field of medical dressing, concretely relates to bacterial cellulose micro-current dressing.

Background

The bacterial cellulose micro-current dressing is an indispensable material in the wound nursing process, and most of the traditional dressings are fabrics such as gauze and polyester fiber, and can play roles in absorbing redundant seepage of the wound, keeping the wound dry, preventing wound infection and the like. However, the dry wound environment is not conducive to wound healing, and secondary wound injury is caused by adhesion between the dressing and the wound during dressing replacement and removal.

With the proposal of the moist wound healing theory, the dressing not only plays an active guiding role in the wound healing process, but also promotes the development of the dressing technology. For example, hydrocolloid dressings, hydrogel dressings, hydrophilic fiber dressings, and the like have been proposed in view of the aforementioned wet wound healing theory.

The bacterial cellulose is natural cellulose without any impurities, has unique properties such as a fine mesh structure, high mechanical strength, good water absorption and retention properties, excellent biocompatibility and biodegradability, and is considered to be cellulose with extreme performance and use value, and is one of the hot spots for international research on biomaterials today.

As known in the art, wound healing is a complex and orderly biological process, which mainly includes inflammatory reaction, cell proliferation or connective tissue formation, wound contraction, wound remodeling and other stages, and re-epithelialization and dermal reconstruction constitute important links of wound healing. The electrical stimulation therapy has the advantages of no wound, simple and convenient operation, wide adaptation diseases, no complications and the like, so the electrical stimulation therapy is accepted by wide medical workers and patients, and the medical application field of the electrical stimulation therapy is continuously widened, such as the functional repair and the tissue repair of nerves, muscles, urinary organs, reproductive systems and skins. In addition, relevant research reports show that the electric stimulation can accelerate wound surface re-epithelialization and revascularization and promote dermis recombination, so that the exploration of the bacterial cellulose micro-current dressing with more excellent functions and structures has positive significance.

Technical information relating to bacterial cellulose dressings, typically "bacterial cellulose medical dressings" as recommended by CN202699408U, is found in published chinese patent literature, which mentions only that bacterial cellulose dressings are in the form of 0.5-8nm blocks or sheets and are synthesized by microorganisms of the genus acetobacter, cultured to produce a reticulated porous structure. The defects of the CN202699408U are as follows: the micro-current effect is not existed, and the micro-current effect refers to that: when in use, the dressing is in contact with normal saline, blood or wound exudate to generate oxidation-reduction reaction, can form a galvanic cell and release micro-current, promotes wound healing through bioelectricity stimulation and has good antibacterial property. It is therefore necessary to improve on the background that the solution described below is made.

Disclosure of Invention

The task of the utility model is to provide a help making nanometer silver oxide and nanometer zinc combine well with bacterial cellulose, be favorable to taking place redox reaction and forming galvanic cell and release little current requirement, be of value to embody good biological electro photoluminescence and promote wound healing and embody the little current dressing of excellent bacterinertness when using.

The utility model discloses a task is accomplished like this, a bacterial cellulose micro-current dressing, including the bacterial cellulose substrate, characterized in that a side surface of bacterial cellulose substrate combines the zinc point and the silver point of protruding in the surface of bacterial cellulose substrate with the interval state to this zinc point forms a relation that separates one each other with the silver point.

In a specific embodiment of the present invention, the thickness of the bacterial cellulose substrate is 0.05-0.2 cm.

In another specific embodiment of the present invention, the spacing distance between the zinc dots and the silver dots is 0.1-0.5 cm.

In a further specific embodiment of the invention, the diameter of the zinc dots is different from the diameter of the silver dots.

In another specific embodiment of the present invention, the diameter of the zinc dots is larger than the diameter of the silver dots.

In still another embodiment of the present invention, the diameter of the zinc dots is 0.2-1cm, and the diameter of the silver dots is 0.1-0.4 cm.

In a more specific embodiment of the present invention, the zinc dots are made of nano zinc, and the silver dots are made of nano silver oxide.

In yet another specific embodiment of the present invention, the bacterial cellulose substrate is shaped as a rectangular body or a circular body.

The technical scheme provided by the utility model the technical effect lie in: the zinc points and the silver points which are protruded from the surface of the bacterial cellulose substrate are combined on the surface of one side of the bacterial cellulose substrate at intervals, so that the combination of the zinc points and the silver points with the bacterial cellulose substrate is realized, the requirements of generating a galvanic cell and releasing micro-current by oxidation-reduction reaction are satisfied when the bacterial cellulose substrate is used, good electrical stimulation is favorably embodied to promote wound healing, and excellent antibacterial property is embodied.

Drawings

Fig. 1 is a structural diagram of a first embodiment of the present invention.

Fig. 2 is a structural diagram of a second embodiment of the present invention.

Detailed Description

Example 1:

referring to fig. 1, a bacterial cellulose substrate 1, which may be referred to as a bacterial cellulose membrane, is shown, and the technical essential of the technical solution provided by the present invention is that a zinc spot 11 and a silver spot 12 protruding from the surface of the bacterial cellulose substrate 1 are combined on one side surface of the bacterial cellulose substrate 1 at intervals, and the zinc spot 11 and the silver spot 12 are in a spaced relationship with each other.

The bacterial cellulose substrate 1 can be obtained from commercial sources or can be obtained by self-manufacturing, and is in the prior art, for example, refer to CN104874015A (a bacterial cellulose dressing with antibacterial and bacteriostatic functions, and a preparation method and application thereof), CN108066814A (a preparation method of a bacterial cellulose antibacterial dressing), and the like, so that the applicant does not need to describe any further.

The thickness of the cellulose substrate 1 is preferably 0.05 to 0.2cm, more preferably 0.1 to 0.18cm, still more preferably 0.12 to 0.16cm, most preferably 0.15cm, and in this embodiment, 0.15cm is selected.

The distance between the zinc dots 11 and the silver dots 12 is preferably 0.1 to 0.5cm, more preferably 0.2 to 0.4cm, most preferably 0.3cm, and in this embodiment, 0.3cm is selected.

The diameter of the aforementioned zinc spot 11 is different from the diameter of the aforementioned silver spot 12, and the diameter of the zinc spot 11 is larger than the diameter of the silver spot 12.

The diameter of the zinc dots 11 is preferably 0.2 to 1cm, more preferably 0.4 to 0.8cm, most preferably 0.6cm, in this example, 0.6cm is selected, and the diameter of the silver dots 12 is preferably 0.1 to 0.4cm, more preferably 0.2 to 0.3cm, most preferably 0.25cm, in this example, 0.25cm is selected.

The zinc dots 11 are formed of nano zinc, the silver dots 12 are formed of nano silver oxide, and the zinc dots 11 and the silver dots 12 are preferably bonded to one surface of the bacterial cellulose substrate 1 by screen printing.

Continuing to refer to fig. 1, in the present embodiment, the bacterial cellulose substrate 1 is rectangular, for example, a cube of 5 × 5cm in a slit manner.

Example 2:

only the bacterial cellulose substrate 1 is formed into a circular shape, for example, a circular shape having a diameter of 4 to 6cm is formed by slitting.

When the bacterial cellulose micro-current dressing in the embodiments 1 to 2 is used, the dressing is in contact with physiological saline, blood or wound exudate, and then the dressing generates an oxidation-reduction reaction, can form a primary battery (can form a voltage of 0.5-0.8V), releases micro-current, promotes wound healing through bioelectricity stimulation and has good antibacterial property.

The applicant places the bacterial cellulose microcurrent dressing described in examples 1 to 2 in a glass plate with a diameter of 90mm, adds 5 mL of simulated body fluid into the plate, drives a voltmeter to a corresponding gear, and tests the voltage of the dressing in the simulated body fluid. The results show that the sample voltage of example 1 is 0.8V, the sample voltage of example 2 is 0.5V, and the bacterial cellulose microcurrent dressing is shown to have redox reaction in the simulated body fluid, and a certain potential difference is formed between the nano silver oxide and the nano zinc.

The applicant carries out antibacterial performance detection on the bacterial cellulose microcurrent dressing in the embodiments 1 to 2 according to the method in the appendix C of GB15979-2002, and the result shows that the bacteriostatic rate of the sample in the embodiment 1 on staphylococcus aureus is greater than 99.9%, and the bacteriostatic rate of the sample in the embodiment 2 on staphylococcus aureus is greater than 99.9%, which indicates that the bacterial cellulose microcurrent dressing in the embodiments 1 to 2 of the present invention has a strong bacteriostatic effect.

Claims

1. A bacterial cellulose microcurrent dressing comprises a bacterial cellulose substrate (1), and is characterized in that zinc dots (11) and silver dots (12) which are protruded from the surface of the bacterial cellulose substrate (1) are combined on one side surface of the bacterial cellulose substrate (1) in a spaced state, and the zinc dots (11) and the silver dots (12) are in a spaced relationship with each other.

2. The bacterial cellulose microcurrent dressing according to claim 1, characterized in that the thickness of the bacterial cellulose substrate (1) is 0.05-0.2 cm.

3. The bacterial cellulose microcurrent dressing according to claim 1, characterized in that the spacing distance between said zinc dots (11) and said silver dots (12) is 0.1-0.5 cm.

4. The bacterial cellulose microcurrent dressing according to claim 1 or 3, characterized in that the diameter of said zinc dots (11) is different from the diameter of said silver dots (12).

5. The bacterial cellulose microcurrent dressing according to claim 4, characterized in that the diameter of said zinc dots (11) is larger than the diameter of said silver dots (12).

6. The bacterial cellulose microcurrent dressing according to claim 5, characterized in that said zinc dots (11) have a diameter of 0.2-1cm and said silver dots (12) have a diameter of 0.1-0.4 cm.

7. The bacterial cellulose microcurrent dressing according to claim 6, characterized in that said zinc spots (11) are constituted by nano zinc and said silver spots (12) are constituted by nano silver oxide.

8. The bacterial cellulose microcurrent dressing according to claim 1 or 2, characterized in that said bacterial cellulose substrate (1) is in the shape of a rectangular or circular body.