CN215019571U - Simple and practical multifunctional mouse fixer - Google Patents

Simple and practical multifunctional mouse fixer Download PDF

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Publication number
CN215019571U
CN215019571U CN202120298325.8U CN202120298325U CN215019571U CN 215019571 U CN215019571 U CN 215019571U CN 202120298325 U CN202120298325 U CN 202120298325U CN 215019571 U CN215019571 U CN 215019571U
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China
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mouse
bottom plate
limbs
door
magnetic
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CN202120298325.8U
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Chinese (zh)
Inventor
杨路
刘芬芳
张继苹
刘明恩
梁丽艳
杨乐
曾婷
文凤
裴婷婷
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Southern Medical University
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Southern Medical University
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Abstract

The utility model discloses a simple and easy practical multi-functional mouse fixer, detain in the cover body on bottom plate surface including bottom plate and cover, four logical grooves that allow mouse four limbs to stretch out are seted up to the bottom plate, and every leads to the groove and all slidable ground is provided with the sliding closure, and the sliding closure lateral wall encloses synthetic four limbs hole with leading to the inslot wall, and the width in slide adjusting four limbs hole through the sliding closure is used for centre gripping mouse four limbs to fix a position the sliding closure through magnetic force component. The utility model discloses a mouse fixer with the mouse restriction in the container that cover body and bottom plate constitute, need not the operation that the laboratory technician made the suppression mouse of hand, avoid the laboratory technician to be attacked by the mouse. The four limbs of the mouse are trapped and clamped and fixed through the four limb holes with the opening size adjustable, and a stable mouse body position is provided, so that the experiment operation is facilitated. The structure is simple, the operation is convenient, and the operation can be carried out by one person.

Description

Simple and practical multifunctional mouse fixer
Technical Field
The utility model belongs to the technical field of medical science experimental device, especially, relate to a simple and easy practical multi-functional mouse fixer.
Background
Medical workers often trigger and discuss disease mechanisms from animal experiments, and can be applied clinically after enough theoretical basis is obtained through animal experiments. In animal experiments, mice are often selected as experimental objects, and some experimental items need to fix the mice to perform experimental steps, so a mouse fixer is often used as an experimental device for fixing the mice.
The existing mouse fixer mainly has two types: one type of fixator completely places four limbs and trunk of the mouse in the container, the function is single, and the posture deviation caused by the torsion and struggle of the mouse in the container can influence the experiment operation; another kind of fixer carries out the clamp respectively to neck, tail root and the truck of mouse and fixes, makes the mouse unable struggle, nevertheless needs the hand-operated suppression mouse to carry out the installation of clamp spare, and the in-process receives the attack of mouse easily, and the installation procedure of clamp spare is loaded down with trivial details, and single-man operation hardly realizes suppressing mouse and installation clamp spare simultaneously.
In view of the shortcoming that current mouse fixer exists, need a novel mouse fixer urgently, can reduce the direct contact of laboratory technician and mouse and avoid laboratory technician's injury, can succinctly conveniently again with mouse four limbs fixed restriction its struggle amplitude, keep mouse position stability to provide good operating condition.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a simple and easy practical multi-functional mouse fixer, realize need not under the prerequisite of manual suppression mouse, fix the body position stability in order to keep the mouse with the four limbs of mouse, the purpose of the experiment operation of being convenient for.
The utility model discloses a realize through following technical scheme:
the utility model provides a simple and easy practical multi-functional mouse fixer, detains the cover body on bottom plate surface including bottom plate and cover, four logical grooves that allow mouse four limbs to stretch out are seted up to the bottom plate, and every leads to the groove and all slidable ground is provided with the sliding closure, and the sliding closure lateral wall encloses synthetic four limbs hole with leading to the inslot wall, and the width in slip regulation four limbs hole through the sliding closure is used for centre gripping mouse four limbs to fix a position the sliding closure through magnetic component.
By the proposal, the utility model discloses at least, obtain following technological effect:
the mouse fixer is a container for loading mice, which is formed by combining a cover body and a bottom plate, and four through grooves are formed in the bottom plate, so that four limbs of the mice can respectively extend out of the four through grooves. Each through groove is slidably matched with a sliding cover, and the side wall of the sliding cover and the inner wall of the through groove enclose a four-limb hole.
When the four-limb-shaped sliding cover is used, the sliding covers are opened towards the two sides of the bottom plate, so that the four-limb holes formed by the side walls of the sliding covers and the inner walls of the through grooves are opened to the maximum. The mouse is placed into the container formed by combining the cover body and the bottom plate, four limbs of the mouse can be trapped in four limb holes, the sliding covers slide towards the central line direction of the bottom plate to narrow the four limb holes, the four limbs of the mouse are respectively clamped and fixed in the four limb holes, and the clamping state is maintained through the magnetic assembly, so that the purpose of respectively fixing the four limbs of the mouse on the premise of not pressing the mouse by hands is achieved.
Preferably, the cover body is provided with a mouse inlet; and a mouse door which can be opened and closed is arranged at the mouse inlet, and the mouse door is provided with a tail hole allowing the tail of the mouse to extend out.
Preferably, the cover body is also provided with a mouse attracting port; the mouse attracting port and the mouse inlet port are oppositely arranged at two ends of the cover body, and a blocking piece for blocking a mouse is arranged in the mouse attracting port.
Preferably, the cross-sectional area of the cover body decreases from the end where the mouse inlet is located to the end where the mouse trapping port is located.
Preferably, the bottom plate is also provided with an abdominal cavity injection hole corresponding to the abdominal position of the mouse; the abdominal cavity injection hole is a long hole.
Preferably, the cover body, the bottom plate and the mouse door are all made of transparent materials.
Preferably, the mouse door is matched with a door lock assembly; the door lock assembly is composed of a hasp and a locking notch, the hasp is connected to the mouse door through a flexible belt, the locking notch is formed in the bottom plate, and the hasp and the locking notch are buckled and matched to lock the mouse door.
Preferably, the magnetic assembly is composed of a first magnetic strip arranged on the inner wall of the through groove and a second magnetic strip arranged on the side wall of the sliding cover; the first magnetic strip and the second magnetic strip are oppositely arranged and mutually attracted.
Preferably, the magnetic assembly is composed of a third magnetic strip and a plurality of magnetic nails, the third magnetic strip is arranged on two opposite inner walls of the through groove, the magnetic nails are divided into two groups, one group is arranged on the side wall of the sliding cover, and the other group is arranged on the inner wall of the through groove opposite to the side wall of the sliding cover.
Preferably, the bottom plate is provided with a plurality of vent holes.
The utility model has the advantages that:
the utility model discloses a mouse fixer with the mouse restriction in the container that cover body and bottom plate constitute, need not the operation that the laboratory technician made the suppression mouse of hand, avoid the laboratory technician to be attacked by the mouse. The four limbs of the mouse are trapped and clamped and fixed through the four limb holes with the opening size adjustable, and a stable mouse body position is provided, so that the experiment operation is facilitated. The structure is simple, the operation is convenient, and the operation can be carried out by one person.
Drawings
Fig. 1 is a schematic view of an axial side structure of a rat fixer according to an embodiment of the present invention.
Fig. 2 is a schematic bottom view of a mouse holder according to an embodiment of the present invention.
Fig. 3 is an enlarged schematic view of a local structure of a limb foramen according to an embodiment of the present invention.
Legend:
1, a bottom plate; 2, covering the body;
11 through grooves; 12 a sliding cover; 13 holes of four limbs; 14 a magnetic assembly; 15 abdominal cavity injection holes; 16 air vents;
21, a mouse inlet; 22 mouse door; 23 mouse attracting port; 24 a dam; 25 a door lock assembly;
141 a first magnetic stripe; 142 a second magnetic stripe; 143 a third magnetic stripe; 144 magnetic nails; 145 card slots;
221 tail holes;
251 a hasp; 252 locking notch; 253 flexible straps.
Detailed Description
The present invention will be further explained with reference to the drawings and examples.
Example 1:
the embodiment provides a simple and practical multifunctional mouse fixer, which comprises a bottom plate 1, a cover body 2, a sliding cover 12, a magnetic assembly 14 and a mouse door 22.
The cover body 2 and the bottom plate 1 are integrally formed to form a semi-cylindrical hollow container for containing a mouse, two ends of the cover body 2 are respectively provided with a mouse inlet 21 and a mouse attracting port 23, a mouse door 22 is arranged at the mouse inlet 21, and the mouse door 22 is connected with the cover body 2 through a hinge so that the mouse door 22 can be turned over and opened. The mouse trapping opening 23 is internally provided with a barrier piece 24 to prevent a mouse from drilling out from the mouse trapping opening 23, the cover body 2 is in a shape of a bunch from one end of the mouse inlet 21 to one end of the mouse trapping opening 23, and the internal space of the fixer is gradually reduced.
The experimenter holds the tail of the mouse to drag the mouse to a state that the head of the mouse is close to the mouse inlet 21, and the mouse can automatically enter the fixer according to the drilling habit of the mouse. And the mouse trapping port 23 can also deceive the sense organ of the mouse to make the sense organ of the mouse mistakenly think that a channel is arranged in the front, so as to trap the mouse to completely enter the fixer, the shape of the convergence of the cover body 2 is matched with the body shape of the mouse with the size of the head and the neck smaller than the size of the trunk, and the mouse is difficult to turn after entering the fixer. The mouse door 22 is closed to prevent the mouse from backing up and escaping. The structure of the fixing device conforms to the habit of the mouse, the mouse can be loaded into the fixing device according to the preset posture without manually adjusting the posture and the position of the mouse, the structure is simple, the operation is convenient, and an experiencer can finish the operation by one person.
The barrier 24 may be a bar-shaped fence, a cross bar, a hollowed-out plate or a hollowed-out structure capable of blocking rats. Not only can ensure the air circulation in the fixer, but also can prevent the mouse from escaping.
The mouse door 22 and the bottom plate 1 are locked through the door lock assembly 25, so that the mouse is prevented from being easily accumulated and agitated when entering the fixator initially and then retreated to prop the mouse door 22 open to escape. The door lock assembly 25 is comprised of a combination of a hasp 251, a locking notch 252 and a flexible band 253. The hasp 251 is mounted on the mouse door 22 through the flexible belt 253, the locking port 252 is arranged on the outer wall surface of the bottom plate 1, and after the mouse door 22 is closed, the hasp 251 and the locking port 252 can be buckled and connected, so that one end of the flexible belt 253 is connected with the mouse door 22, and the other end of the flexible belt 253 is connected with the bottom plate 1, and the effect of preventing the mouse door 22 from being knocked open by a mouse is achieved.
The rat door 22 is provided with the tail hole 221, the tail hole 221 is located in the center of the bottom of the rat door 22, the tail of the rat can be exposed outside the fixator, and experiments such as tail vein injection, tail root injection, rat tail blood sampling, rat tail thermal stimulation and the like can be conveniently carried out.
Four rectangular through grooves 11 are formed in the positions, corresponding to four limbs of a mouse, of the bottom plate 1, the sizes of notches of the four through grooves 11 are larger than those of the four limbs of the mouse, and the four limbs of the mouse are trapped in the through grooves 11 in the crawling process of the fixing device. A sliding cover 12 is slidably arranged in each through groove 11, and the side wall of the sliding cover 12 facing the central line of the bottom plate 1 and the adjacent three inner walls of the through grooves 11 enclose a rectangular limb hole 13. The sliding direction of the sliding cover 12 is parallel to the plate surface of the bottom plate 1, the sliding cover 12 slides towards the direction of the center line of the bottom plate 1 to narrow the four-limb hole 13, and the four limbs of the mouse trapped in the through groove 11 are clamped to prevent the mouse from being pulled out. The clamping state of the four-limb holes 13 on the four limbs of the mouse is kept through the magnetic assembly 14, and the effect of fixing the mouse is achieved.
The adjustable limb holes 13 have the fixing effect, and are convenient for conducting electrocardio-electromyography guidance, plantar thickness measurement, ankle joint diameter measurement, plantar volume measurement, knee joint cavity injection and other limb experiments on the mouse.
If the mouse does not sink into through groove 11 at the in-process four limbs of crawling, accessible clamp etc. instrument stretch into the fixer from four limbs hole 13 in with the four limbs of mouse drag into four limbs hole 13 and readjust sliding closure 12 and fix.
The four limb holes 13 are grouped in pairs, one group is a front limb hole group which is close to the mouse attracting port 23 and used for fixing two front limbs of the mouse, and the other group is a rear limb hole group which is close to the mouse inlet 21 and used for fixing two rear limbs of the mouse.
An abdominal cavity injection hole 15 is formed in the bottom plate 1 between the front limb hole group and the rear limb hole group and is used for performing injection experiments on mice in the fixator outside the fixator. During injection experiments, the abdominal cavity injection needle inlet points are positioned on two sides of a mouse abdominal median line, so that the abdominal cavity injection hole 15 is a long hole, the long axis of the abdominal cavity injection hole is perpendicular to the central line of the bottom plate 1, the abdominal cavity injection hole 15 stretches across the abdomen of a mouse, and the effect of carrying out various injection operations on a plurality of needle inlet points on the abdomen of the mouse is achieved by matching with the length of the needle head of the injection needle.
Considering that the abdominal region of the mouse is the lower abdominal region to avoid the liver, spleen, stomach and other organs in the upper abdominal region of the mouse, the abdominal injection hole 15 is biased to the hind limb hole group.
The mouse fixer can be adapted to mice of different body types. The distance between the front and rear limbs is longer if the mouse is large, and shorter if the mouse is small. The sliding direction of the sliding cover 12 in the four-limb hole 13 is towards the center line of the bottom plate 1 or in the opposite direction, namely the sliding direction of the sliding cover 12 is perpendicular to the center line of the bottom plate 1, so that the four-limb hole 13 is a rectangular groove hole with a long axis parallel to the center line of the bottom plate 1, and the length of the four-limb hole can be used for adapting to different body types of mice.
Two forelimbs of a large mouse are held by the forelimb hole group at a position deviated from the mouse attracting port 23, and two hindlimbs are held by the hindlimb hole group at a position deviated from the mouse entering port 21. The size of the mouse is smaller, so that two forelimbs of the mouse are clamped at the position deviated to the abdominal cavity injection hole 15 by the forelimb hole group, and two hindlimbs of the mouse are clamped at the position deviated to the abdominal cavity injection hole 15 by the hindlimb hole group. The limbs of the mouse can be simultaneously inserted into the limb holes 13 to clamp and fix the mouse.
In order to observe and record the mouse in the experimental process, the cover body 2, the bottom plate 1 and the mouse door 22 are made of transparent materials. Transparent plastic or transparent glass can be selected.
In the experiment process, if the head of the mouse contracts towards the trunk and is far away from the mouse attracting port 23, a slight oxygen deficiency symptom may occur due to the low oxygen content in the semi-closed fixer, and then the medical experiment result is interfered. Therefore, a plurality of vent holes 16 are arranged on the bottom plate 1 between the forelimb hole group and the mouse trapping opening 23. Ensure the air circulation of the range of the head of the mouse.
The magnetic assembly 14 is intended to maintain the grip state of the limb holes 13 on the limbs of the mouse. The sliding cover 12 has the tendency of continuously reducing the holes 13 of the four limbs through the magnetic attraction effect, and the clamping effect is realized by applying pressure on the four limbs of the mouse. The magnetic assembly 14 has a great variety of structural types, and the present embodiment provides two embodiments of the magnetic assembly 14:
the first magnetic assembly 14 is composed of a combination of a first magnetic strip 141 and a second magnetic strip 142. The first magnetic strips 141 are arranged on the inner wall of the through groove 11, the second magnetic strips 142 are arranged on the side wall of the sliding cover 12, the magnetic poles at the opposite ends of the two magnetic strips are different to generate the mutual attraction effect, and the mutual attraction is used as the clamping force of the side wall of the sliding cover 12 and the inner wall of the through groove 11 on the four limbs of the mouse.
The second magnetic assembly 14 is composed of two third magnetic strips 143 and a plurality of magnetic nails 144, the two third magnetic strips 143 are respectively disposed on two opposite inner walls of the through slot 11, the magnetic nails 144 are divided into two groups, one group is fixed on the sliding cover 12, the other group is fixed on the inner wall of the through slot 11 between the two third magnetic strips 143, and the magnetic nails 144 on the sliding cover 12 generate a movement trend towards the central line of the bottom plate 1 under the magnetic field effect of the third magnetic strips 143 on the two sides, so that the sliding cover 12 clamps the four limbs of the mouse. And the two groups of magnetic nails 144 can attract each other to enhance the clamping effect.
It should be noted that, in order to prevent the sliding cover 12 from falling off the through slot 11 to the side of the fixer, a clamping slot 145 is further provided to limit the sliding cover 12.
Example 2:
the embodiment further provides an operation method of the simple and practical multifunctional mouse fixer, which adopts the simple and practical multifunctional mouse fixer in embodiment 1 and implements the following steps:
step one, a mouse enters a fixer: the fixing device is placed on an experiment table, the mouse door 22 is turned upwards and opened, an experimenter pulls the tail of a mouse or grasps the back skin of the mouse, the head of the mouse is placed beside the fixing device just opposite to the mouse inlet 21, the mouse can automatically enter the fixing device according to the habit of drilling holes by the mouse, and the mouse door 22 is closed after the mouse completely enters the fixing device. If the mouse struggles and restlesss, the mouse door 22 can be locked through the door lock assembly 25, and the mouse is prevented from escaping.
Step two, mouse posture adjustment: if the abdomen of the mouse in the fixer is not over against the bottom plate 1, the fixer can be rotated to force the mouse to move until the abdomen of the mouse over against the bottom plate 1 meets the experimental requirements.
Step three, fixing four limbs: on the premise that the posture of the mouse is correct, the fixator is lifted off the experiment table or suspended by a support, so that the four limbs of the mouse extend out of the fixator bottom plate 1 from the four limb holes 13. If the rat is frightened, the experimenter can extend into the fixer from the limb hole 13 through a clamp or other tools to forcibly pull out the limbs of the rat. Through sliding the sliding cover 12, adjust the size of four limbs hole 13 and make four limbs hole 13 centre gripping mouse four limbs to keep the centre gripping state through magnetic force component 14.
And step four, performing injection experiments on limbs, tails and abdomens.
And step five, after the experiment is finished, unlocking the door lock assembly 25, opening the mouse door 22 and taking out the mouse.
Various technical features in the above embodiments may be arbitrarily combined as long as there is no conflict or contradiction in the combination between the features, but is limited to the space and is not described one by one.
The present invention is not limited to the above embodiment, and various modifications and variations of the present invention are intended to be included within the scope of the claims and the equivalent technology if they do not depart from the spirit and scope of the present invention.

Claims (10)

1. The utility model provides a simple and easy practical multi-functional mouse fixer which characterized in that: detain the cover body on bottom plate surface including bottom plate and cover, four logical grooves that allow mouse four limbs to stretch out are seted up to the bottom plate, and every leads to the groove and all slidably to be provided with the sliding closure, and the sliding closure lateral wall encloses synthetic four limbs hole with leading to the inslot wall, and the width in slide adjustment four limbs hole through the sliding closure is used for centre gripping mouse four limbs to fix a position the sliding closure through magnetic assembly.
2. The simple and practical multifunctional mouse fixer according to claim 1, wherein the cover body is provided with a mouse inlet; and a mouse door which can be opened and closed is arranged at the mouse inlet, and the mouse door is provided with a tail hole allowing the tail of the mouse to extend out.
3. The simple and practical multifunctional mouse fixer according to claim 2, wherein the cover body is further provided with a mouse attracting port; the mouse attracting port and the mouse inlet port are oppositely arranged at two ends of the cover body, and a blocking piece for blocking a mouse is arranged in the mouse attracting port.
4. The simple and practical multifunctional mouse fixer according to claim 3, wherein the cross-sectional area of the cover body decreases from the mouse inlet end to the mouse trapping end.
5. The simple, practical and multifunctional mouse fixer according to claim 1, wherein the bottom plate is further provided with an abdominal cavity injection hole corresponding to the abdominal position of the mouse; the abdominal cavity injection hole is a long hole.
6. The simple and practical multifunctional mouse fixer according to claim 1, wherein the cover body, the bottom plate and the mouse door are made of transparent materials.
7. The simple and practical multifunctional mouse fixer according to claim 2, characterized in that the mouse door is matched with a door lock assembly; the door lock assembly is composed of a hasp and a locking notch, the hasp is connected to the mouse door through a flexible belt, the locking notch is formed in the bottom plate, and the hasp and the locking notch are buckled and matched to lock the mouse door.
8. The simple and practical multifunctional mouse holder according to claim 1, wherein the magnetic assembly is composed of a first magnetic strip mounted on the inner wall of the through slot and a second magnetic strip mounted on the side wall of the sliding cover; the first magnetic strip and the second magnetic strip are oppositely arranged and mutually attracted.
9. The simple and practical multifunctional mouse fixer according to claim 1, wherein the magnetic assembly is composed of a third magnetic strip and a plurality of magnetic nails, the third magnetic strip is disposed on two opposite inner walls of the through slot, the plurality of magnetic nails are divided into two groups, one of the groups is disposed on the side wall of the sliding cover, and the other group is disposed on the inner wall of the through slot opposite to the side wall of the sliding cover.
10. The simple and practical multifunctional mouse fixer according to claim 1, wherein the bottom plate is provided with a plurality of air vents.
CN202120298325.8U 2021-02-02 2021-02-02 Simple and practical multifunctional mouse fixer Active CN215019571U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120298325.8U CN215019571U (en) 2021-02-02 2021-02-02 Simple and practical multifunctional mouse fixer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120298325.8U CN215019571U (en) 2021-02-02 2021-02-02 Simple and practical multifunctional mouse fixer

Publications (1)

Publication Number Publication Date
CN215019571U true CN215019571U (en) 2021-12-07

Family

ID=79258552

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202120298325.8U Active CN215019571U (en) 2021-02-02 2021-02-02 Simple and practical multifunctional mouse fixer

Country Status (1)

Country Link
CN (1) CN215019571U (en)

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