CN215017262U - General pain measuring box for experimental rats and mice - Google Patents
General pain measuring box for experimental rats and mice Download PDFInfo
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- CN215017262U CN215017262U CN202121157586.4U CN202121157586U CN215017262U CN 215017262 U CN215017262 U CN 215017262U CN 202121157586 U CN202121157586 U CN 202121157586U CN 215017262 U CN215017262 U CN 215017262U
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- 241000700159 Rattus Species 0.000 title claims abstract description 15
- 241000699670 Mus sp. Species 0.000 title claims abstract description 14
- 241000699666 Mus <mouse, genus> Species 0.000 claims abstract description 23
- 239000002184 metal Substances 0.000 claims abstract description 12
- 230000001413 cellular effect Effects 0.000 claims 1
- 238000011156 evaluation Methods 0.000 abstract description 10
- 238000010171 animal model Methods 0.000 abstract description 5
- 210000001015 abdomen Anatomy 0.000 abstract description 4
- 210000004392 genitalia Anatomy 0.000 abstract description 4
- 210000002307 prostate Anatomy 0.000 abstract description 2
- 238000002474 experimental method Methods 0.000 description 5
- 238000011160 research Methods 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012854 evaluation process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
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Abstract
The utility model discloses a general pain measuring box for experimental rats and mice, a serial communication port, including support (6), be equipped with cellular-type black box (1) on support (6), be equipped with metal grid (2) in cellular-type black box (1), be equipped with reflector (4) below metal grid (2). The utility model discloses a many experimental mice can be packed into to the black case of cellular-type, and the reflector is adopted to the bottom, and multiple ventral pain models such as belly, genitals, prostate, sole according to different experimental animals carry out parallel, high-efficient, stable painful evaluation, cost of using manpower sparingly and time cost. Utilize the little black box of detachable, can realize big mouse multipurpose, improve experimental efficiency, increase the stability of painful evaluation.
Description
Technical Field
The utility model relates to a general pain measuring box for experimental rats and mice, which belongs to the technical field of animal experimental equipment.
Background
Pain is one of important factors disturbing human life and is a main treatment disease category of a common rehabilitation medical science, pain rehabilitation evaluation is an important index for researching various pain model animals, a common pain evaluation means such as a Von-frey method is widely accepted at present, but environmental factors play a key factor in a pain evaluation process, and operation actions and light changes of scientific researchers are inevitable in a quiet environment, so that interference is brought to pain evaluation, and the accuracy of pain evaluation is seriously influenced. The current experimental box for pain assessment comprises a transparent experimental box and a simple bracket.
1. Transparent experimental box
The transparent experimental box is convenient for scientific research personnel to observe the stimulation response of the experimental mouse to pain, and the scientific research personnel can adjust the Von-frey filaments with different thicknesses to measure the pain according to the stimulation response of the experimental mouse.
The disadvantages are as follows:
(1) the transparent box causes the operation action of scientific research personnel and the change of ambient light to influence the pain stimulation reaction of the laboratory mouse, so that the pain measurement result is unstable.
(2) In order to facilitate observation, particularly for measuring pain of soles, genitals and abdomens of the experimental mouse, the experimental box needs to be placed at a high position, so that the carrying is not facilitated, the experimental efficiency is reduced, and meanwhile, the influence of environmental variables on the experimental mouse is increased.
2. Simple support
The simple support is used for measuring pain, the laboratory mouse is placed in a grid support mode, and then the laboratory mouse is sleeved with the box.
The disadvantages are as follows:
(1) only one experimental mouse can be measured at a time, and the experimental efficiency is very low because the experimental mouse needs to be pre-adapted in advance before pain occurs each time.
(2) In order to facilitate observation, particularly for measuring pain of soles, genitals and abdomens of the experimental mouse, the experimental box needs to be placed at a high position, so that the carrying is not facilitated, the experimental efficiency is reduced, and meanwhile, the influence of environmental variables on the experimental mouse is increased.
(3) Since only one test mouse can be measured at a time, it is difficult to set up a control group, and pain evaluation comparison cannot be performed at the same time.
Chinese patent 200920154972.0 discloses a simple and easy dual-purpose pain measuring instrument of heat machinery, and the animal that wherein uses places the bounding box, and it is inconvenient to have the observation, uses the trouble, and the box size can not adapt to experiment big mouse scheduling problem.
Disclosure of Invention
An object of the utility model is to provide a general pain box of surveying of experiment size mouse realizes that experimental animals surveys parallel contrast, high efficiency, the painful evaluation of accuracy of pain to can combine compatible rat and mouse simultaneously, realize the painful evaluation of multipurpose.
In order to solve the technical problem, the utility model discloses a following technical scheme: the pain measuring box for the experimental rat and the experimental rat comprises a support, wherein a separated black box is arranged on the support, a metal grid is arranged in the separated black box, and a reflector is arranged below the metal grid.
The pain measuring box for the experimental rats and the experimental rats further comprises a small black box in the separated black box.
The pain measuring box for the experimental rats and mice is characterized in that the small black box is 8-12cm long, 5-7cm wide and 10-14cm high.
The separated black box is 18-22cm long, 12-14cm wide and 16-18cm high.
In the pain measuring box for the experimental rats and the experimental rats, the top of the separated black box is provided with the transparent cover plate.
In the pain measuring box for the big and small experimental mice, the reflector is obliquely arranged, and the inclination angle of the reflector and the bottom is 30-60 degrees.
Compared with the prior art, the utility model discloses a many experimental mice can be packed into to the black case of cellular-type, and the reflector is adopted to the bottom, and multiple ventral pain models such as belly, genitals, prostate, sole according to different experimental animals carry out parallel, high-efficient, stable pain assessment, use manpower sparingly cost and time cost. Utilize the little black box of detachable, can realize big mouse multipurpose, improve experimental efficiency, increase the stability of painful evaluation.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Reference numerals: 1-a partitioned black box, 2-a metal grid, 3-a small black box, 4-a reflector, 5-a transparent cover plate and 6-a bracket.
The following description is given with reference to the accompanying drawings and the detailed description, but not to limit the present invention.
Detailed Description
The separated black box 1 also comprises a small black box 3 which can be used for holding experimental mice with different sizes. The black baffle of cellular-type black box 1 and removable little black box 3 of disassembling can effectively avoid scientific research personnel to operate, the influence of ambient light change to experimental animals.
Through tests, the small black box 3 is 8-12cm long, 5-7cm wide and 10-14cm high, and the partitioned black box 1 is 18-22cm long, 12-14cm wide and 16-18cm high, and is appropriate in size.
The top of the separated black box 1 is provided with a transparent cover plate 5, so that observation is facilitated.
The reflector 4 is obliquely arranged, the inclination angle of the reflector and the bottom is 30-60 degrees, and the reflecting effect is good.
The working principle is as follows: according to different types of experimental animals, a rat can be directly placed into the separated black box 1, or a detachable small black box 3 is placed into the separated black box 1, and then a mouse is placed, so that the universal use of the rat and the mouse is realized. And (3) inserting pain measuring equipment into the metal grid 2 below the partitioned black box 1 to perform an experiment, and observing the pain reaction of the experimental mouse through a reflector 4.
The separated black box 1 also comprises a small black box 3 which can be used for holding experimental mice with different sizes. The small black box 3 is 10cm long, 6cm wide and 12cm high, and the separated black box 1 is 20cm long, 13cm wide and 17cm high.
The reflecting mirror 4 is obliquely arranged, and the inclined angle of the reflecting mirror 4 and the bottom is 45 degrees.
Claims (6)
1. The utility model provides a general pain measuring box of experimental big mouse, its characterized in that includes support (6), is equipped with cellular-type black box (1) on support (6), is equipped with metal mesh (2) in cellular-type black box (1), is equipped with reflector (4) below metal mesh (2).
2. The universal pain measuring box for laboratory mice according to claim 1, wherein the partitioned black box (1) further comprises a small black box (3).
3. The pain box for laboratory rats according to claim 2, wherein the small black box (3) has a length of 8-12cm, a width of 5-7cm and a height of 10-14 cm.
4. The universal pain measuring box for laboratory mice according to claim 1, wherein the partitioned black box (1) has a length of 18-22cm, a width of 12-14cm and a height of 16-18 cm.
5. The universal pain measuring box for laboratory mice according to claim 1, wherein the top of the cellular black box (1) is provided with a transparent cover plate (5).
6. The universal pain measuring box for laboratory mice according to claim 1, wherein the reflector (4) is inclined at an angle of 30-60 ° with respect to the bottom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121157586.4U CN215017262U (en) | 2021-05-27 | 2021-05-27 | General pain measuring box for experimental rats and mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121157586.4U CN215017262U (en) | 2021-05-27 | 2021-05-27 | General pain measuring box for experimental rats and mice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN215017262U true CN215017262U (en) | 2021-12-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN202121157586.4U Active CN215017262U (en) | 2021-05-27 | 2021-05-27 | General pain measuring box for experimental rats and mice |
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| Country | Link |
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| CN (1) | CN215017262U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024092383A1 (en) * | 2022-10-31 | 2024-05-10 | 中国科学院深圳先进技术研究院 | Device for detecting waist and back pains in small animals |
-
2021
- 2021-05-27 CN CN202121157586.4U patent/CN215017262U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024092383A1 (en) * | 2022-10-31 | 2024-05-10 | 中国科学院深圳先进技术研究院 | Device for detecting waist and back pains in small animals |
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