CN215005421U - Enzyme-labeling instrument - Google Patents

Abstract

The utility model discloses an ELIASA, including the ELIASA main part, be provided with the slot that extends along the horizontal direction in the ELIASA main part, the slot is pegged graft and is cooperated with sample storage, and sample storage includes the ELIASA, and the top surface of ELIASA is provided with a plurality of isolated and sample storage that the rectangle array distributes sunken, and the top lid that sample storage is sunken is equipped with the sealing member, and the material of sealing member is the printing opacity material. The ELIASA seals the sample storage recess on the ELIASA plate through the sealing element, prevents the sample from splashing out of the sample storage recess in the detection process, avoids mixing of sample solutions, improves the detection precision of equipment, avoids the sample from splashing into the ELIASA body, and ensures the safe operation of the equipment; the device is simple in structure, and complex precise instruments such as an electric push rod and the like do not need to be installed, so that the production cost of the device is reduced.

Description

Enzyme-labeling instrument

Technical Field

The utility model belongs to the technical field of the detecting instrument technique and specifically relates to an ELIASA is related to.

Background

The microplate reader is also called as a microplate detector, can provide detection in various different modes for experiments using a microplate as a system, and generally, the microplate reader can provide at least three different detection modes of 'light absorption', 'fluorescence' and 'luminescence'.

When the ELIASA uses, need to be equipped with the ELIASA board of sample and put into the ELIASA, because the ELIASA board is uncovered structure, when its translation rate is inconsistent, the sample spills easily, pollutes ELIASA internal environment, influences the testing result, still can lead to the ELIASA to damage when serious. For this reason, the utility model discloses a chinese utility model patent document that bulletin number is CN212364311U discloses a take multi-functional ELIASA of flexible layer board, including the ELIASA body, first mounting groove has been seted up in the front of ELIASA body, and the equal fixed mounting in left side inner wall and the right side surface of first mounting groove has miniature electric putter, the equal fixedly connected with baffle in surface that two miniature electric putter are relative, and the inner bottom wall center department of first mounting groove is provided with automatic telescopic machanism, and automatic telescopic machanism is including the layer board, the inner bottom wall center department of first mounting groove and the lower surface sliding connection of layer board. The automatic layer board that will pull out and impel the use in the inside of ELIASA body of this ELIASA, the realization is pulled out and impeld layer board speed is even, avoids causing the effect of the sample spill in the ELIASA board.

The microplate reader drives the supporting plate and the microplate on the supporting plate to move at a constant speed through the automatic telescopic mechanism, so that a sample is prevented from splashing, but the output speed of the electric push rod needs to be ensured to be uniform, the precision requirement on equipment is high, the equipment structure is complex, and the production cost is increased; and, the ELIAS plate still is uncovered structure, and when testing platform or ELIAS appearance took place to vibrate, the sample on the ELIAS plate spills easily, not only influences the testing result, still causes the damage to equipment easily.

Accordingly, there is a need for improvements in prior art microplate readers.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to overcome the defect that exists among the prior art, provide a simple structure, with low costs, prevent the ELIASA of sample spill in order to guarantee testing result and security.

In order to realize the technical effects, the utility model adopts the technical scheme that: the utility model provides an ELIASA, includes the ELIASA main part, be provided with the slot that extends along the horizontal direction in the ELIASA main part, the slot is pegged graft and is cooperated with sample storage spare, sample storage spare includes the ELIASA, the top surface of ELIASA is provided with a plurality of isolated and sample storage that the rectangle array distributes sunken, the top lid in sample storage sunken is equipped with the sealing member, the material of sealing member is the printing opacity material.

Preferably, the encapsulant is in the form of a sheet in order to reduce the loss of detection light from the light source through the encapsulant.

Preferably, in order to facilitate the connection between the sealing element and the elisa plate and prevent the loss of either of the sealing element and the elisa plate, the sealing element is rotationally connected with the elisa plate, and the axis of rotation of the sealing element is parallel to the plate surface of the elisa plate.

Preferably, in order to fix the relative position between the sealing element and the sealing plate, a positioning recess and a positioning protrusion which are in plug-in fit are arranged between the sealing element and the elisa plate.

Preferably, in order to seal an opening of the sample storage recess, the sealing member is provided with a plurality of sealing recesses, the sealing recesses correspond to the sample storage recesses one to one, and a circumferential outer side wall of each sealing recess is in sealing connection with a circumferential inner side wall of each sample storage recess.

Preferably, to ensure the seal, a resilient sealing ring is provided between the sealing recess and the sample storage recess.

Preferably, in order to reduce the cost of the sealing ring, the material of the sealing ring is rubber, silica gel or sponge.

Preferably, in order to facilitate the insertion of the sealing recess into the sample storage recess, the bottom of the sealing recess is a plug portion, the size of the bottom end of the plug portion is smaller than that of the top end, and the bottom end of the plug portion gradually transitions to the top end.

Preferably, in order to filter the detection light through the sealing recess, an optical filter is not needed in the detector body, and the optical filter is convenient to clean, and the bottom wall of the sealing recess is the optical filter.

Preferably, in order to facilitate the insertion and extraction of the sample storage member, an operation protrusion is arranged on one side of the sample storage member, which faces away from the insertion direction of the sample storage member, and the operation protrusion protrudes out of the slot.

To sum up, the utility model discloses the ELIASA seals the sample storage recess on the ELIASA plate through the sealing member, prevents that the sample from spilling from the sample storage recess in the testing process, avoids mixing between the sample solution, has improved the precision of equipment detection to avoid the sample to spill in the ELIASA body, guaranteed the equipment safe operation; the device is simple in structure, and complex precise instruments such as an electric push rod and the like do not need to be installed, so that the production cost of the device is reduced.

Drawings

Fig. 1 is a schematic structural diagram of embodiment 1 of the present invention;

FIG. 2 is a schematic structural diagram of a sample storage member according to embodiment 1 of the present invention;

FIG. 3 is a cross-sectional view of the use of FIG. 2;

fig. 4 is a schematic structural diagram of a sample storage member according to embodiment 2 of the present invention;

FIG. 5 is an enlarged view of portion A of FIG. 4;

in the figure: 1. the microplate reader comprises a microplate reader body, 1-1 slots, 2 sample storage pieces, 3 enzyme label plates, 3-1 sample storage recesses, 3-2 positioning protrusions, 4 sealing pieces, 4-1 positioning recesses, 4-2 sealing recesses, 5 sealing rings, 6 operation protrusions, 7 supports, 8 touch screens and 9 hinges.

Detailed Description

The following description will further describe embodiments of the present invention with reference to the accompanying drawings and examples. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.

Example 1

As shown in fig. 1 to 3, the microplate reader of embodiment 1 includes a microplate reader main body 1, a support 7 is fixed below the microplate reader main body 1, a touch screen 8 is arranged above the microplate reader main body 1, a slot 1-1 is opened on one side of the microplate reader main body, the slot 1-1 extends along the horizontal direction and is in insertion fit with a sample storage member 2; the sample storage part 2 comprises an ELISA plate 3 and a sheet-shaped sealing part 4 arranged above the ELISA plate 3, the material of the sealing part 4 is transparent polystyrene, one side of the sealing part is rotationally connected with the ELISA plate 3 through a hinge 9, and the rotating axis line of the sealing part 4 is parallel to the plate surface of the ELISA plate 3; the top surface of the ELISA plate 3 is provided with a plurality of sample storage depressions 3-1 which are separated from each other and distributed in a rectangular array, and when the sealing element 4 rotates to be parallel to the ELISA plate 3, the sealing element 4 covers the sample storage depressions 3-1; one side of the ELISA plate 3 is provided with an operation bulge 6, and the operation bulge 6 protrudes out of the slot 1-1.

When the microplate reader of the embodiment is used, the sample storage member 2 formed by combining the microplate 3 and the sealing member 4 is conveniently taken out of the slot 1-1 by operating the protrusion 6; the sealing piece 4 is rotated through the hinge 9, so that the sample storage recess 3-1 on the ELISA plate 3 is opened, and a sample solution is conveniently added into the sample storage recess 3-1; then, the sealing member 4 is covered to close the sample storage recess 3-1, the sample storage member 2 is inserted into the insertion slot 1-1, and the touch screen 8 is operated to perform the detection. At the moment, the sample storage recess 3-1 is sealed by the sealing element 4, so that the sample in the sample storage recess 3-1 is prevented from splashing outside the ELISA plate 3, the sample solution is prevented from being mixed to influence the detection precision, and the sample is prevented from being easily isolated from the device in the main body 1 of the ELISA reader, thereby being beneficial to the safety detection of equipment; in addition, the microplate reader has a simple structure, and does not need to be provided with a high-density electric push rod (even if the speed is inconsistent in the process of inserting and taking out the sample storage part 2, the sample solution cannot splash to the outside), so that the microplate reader has a simple structure, and is favorable for reducing the production cost of equipment.

It should be noted that, the sealing member 4 material chooses polystyrene for use to convenient printing opacity, lamellar design has reduced the loss amount when detecting light and passing through sealing member 4, and as the replacement of similar effect, sealing member 4 can also choose other transparent materials for use.

Example 2

As shown in fig. 4 and 5, the microplate reader of embodiment 2 is based on embodiment 1, and is different in that a through-hole-shaped positioning recess 4-1 is formed in a sealing member 4, and a positioning protrusion 3-2 which is in insertion fit with the positioning recess 4-1 is formed on the top surface of an microplate 3; the sealing element 4 is also provided with sealing depressions 4-2 which are in one-to-one correspondence with the sample storage depressions 3-1 and have upward openings, the circumferential outer side wall of the sealing depression 4-2 is hermetically connected with the circumferential inner side wall of the sample storage depression 3-1, and the circumferential side wall of the top of the sample storage depression 3-1 is provided with a sealing ring 5 made of rubber; the bottom of the sealing recess 4-2 is a plug-in part, the size of the bottom end of the plug-in part is smaller than that of the top end, and the bottom end of the plug-in part gradually transits to the top end; the bottom wall of the sealing recess 4-2 is a filter.

In this embodiment, the sealing member 4 and the microplate 3 can be separated from each other up and down, and when the two are combined together, the positioning recess 4-1 and the positioning protrusion 3-2 facilitate the insertion of the sealing recess 4-2 on the sealing member 4 into the sample storage recess 3-1, and prevent the sample storage member 2 from moving in the horizontal direction, while keeping the two moving synchronously, thereby avoiding the separation between the sealing member 4 and the microplate 3. As an alternative to the similar effect, the positioning recess 4-1 and the positioning protrusion 3-2 may be disposed on the microplate 3 and the sealing member 4, respectively, and the positioning recess 4-1 may also be in the form of a blind hole.

The sealing ring 5 made of rubber is arranged on the circumferential side wall of the top of the sample storage recess 3-1, so that the sealing connection between the sealing recess 4-2 and the sample storage recess 3-1 is facilitated to be enhanced, the sample is further prevented from being splashed out of the ELISA plate 3, the sealing ring 5 is made of rubber and has elasticity, and the tightness is enhanced through elastic deformation, so that the sealing ring 5 can also be made of other elastic materials such as sponge and silica gel as a replacement with similar effects. In addition, the above-mentioned restriction is made to the insertion end of the sealing recess 4-2, thereby facilitating smooth insertion of the insertion end into the sample storage recess 3-1.

After the bottom wall of the sealing recess 4-2 is the optical filter, the optical filter does not need to be arranged in the microplate reader main body 1, the optical filter can be conveniently cleaned, and the influence on the measurement result after the optical filter is stained with dust and impurities is avoided.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the technical principle of the present invention, and these improvements and decorations should also be regarded as the protection scope of the present invention.

Claims (10)

1. The utility model provides an ELIASA, includes ELIASA main part (1), be provided with slot (1-1) that extend along the horizontal direction on ELIASA main part (1), slot (1-1) grafting cooperation has sample storage spare (2), sample storage spare (2) include ELIASA board (3), the top surface of ELIASA board (3) is provided with sample storage sunken (3-1) that a plurality of isolated and rectangle array distribute, its characterized in that:

and a sealing piece (4) is covered above the sample storage recess (3-1), and the sealing piece (4) is made of a light-transmitting material.

2. The microplate reader of claim 1, wherein: the seal (4) is in the form of a sheet.

3. The microplate reader of claim 1, wherein: the sealing element (4) is rotationally connected with the ELISA plate (3), and the rotation axis line of the sealing element (4) is parallel to the plate surface of the ELISA plate (3).

4. The microplate reader of claim 1, wherein: a positioning recess (4-1) and a positioning protrusion (3-2) which are in plug-in fit are arranged between the sealing element (4) and the ELISA plate (3).

5. The microplate reader of claim 4, wherein: the sealing element (4) is provided with a plurality of sealing recesses (4-2), the sealing recesses (4-2) are in one-to-one correspondence with the sample storage recesses (3-1), and the circumferential outer side wall of each sealing recess (4-2) is in sealing connection with the circumferential inner side wall of each sample storage recess (3-1).

6. The microplate reader of claim 5, wherein: an elastic sealing ring (5) is arranged between the sealing recess (4-2) and the sample storage recess (3-1).

7. The microplate reader of claim 6, wherein: the sealing ring (5) is made of rubber, silica gel or sponge.

8. The microplate reader of claim 5, wherein: the bottom of the sealing recess (4-2) is provided with an inserting part, the size of the bottom end of the inserting part is smaller than that of the top end of the inserting part, and the bottom end of the inserting part gradually transits to the top end of the inserting part.

9. The microplate reader of claim 5, wherein: the bottom wall of the sealing recess (4-2) is an optical filter.

10. The microplate reader of claim 1, wherein: one side of the sample storage piece (2) back to the plugging direction of the sample storage piece is provided with an operation bulge (6), and the operation bulge (6) protrudes out of the slot (1-1).

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