CN214974174U

CN214974174U - Be used for timely testing platform of exosome

Info

Publication number: CN214974174U
Application number: CN202121274283.0U
Authority: CN
Inventors: 王建国; 吉永新
Original assignee: Nanjing Nanoeast Biotech Co ltd
Current assignee: Nanjing Nanoeast Biotech Co ltd
Priority date: 2021-06-08
Filing date: 2021-06-08
Publication date: 2021-12-03
Anticipated expiration: 2031-06-08

Abstract

The utility model belongs to the biotechnology field, in particular to a timely detection platform for exosomes, which comprises a rack, wherein one side of the top of the rack is provided with a through groove, one side of the top of the rack, which is far away from the through groove, is provided with a storage groove, the top of the rack is close to one side of the through groove, the bottom of the support mechanism is slidably provided with a rack rod, the outer side of the rack rod is slidably provided with a connecting mechanism, the inner side of the connecting mechanism is fixedly clamped with a bearing, the inner side of the bearing is rotatably connected with a rotating seat, one side of the rotating seat is communicated with an air outlet pipe, the outer side of the air outlet pipe is communicated with a plurality of groups of air nozzles, the outer side of the air outlet pipe is sleeved with a roller, the inner side of the roller is in a cavity arrangement, the inner side of the roller is provided with air holes corresponding to the plurality of groups of air nozzles, the utility model can conveniently clean water stains and dust on the surface of the detection platform in time, the cleaning burden of subsequent users is reduced.

Description

Be used for timely testing platform of exosome

Technical Field

The utility model belongs to the technical field of it is biological, specifically disclose a be used for timely testing platform of exosome.

Background

Exosomes are extracellular vesicles with the size of 30-150nm, are naturally present in body fluid, including blood, saliva, urine, cerebrospinal fluid and milk, are found to be important carriers for intercellular communication at present, the amount of exosomes secreted by known tumor cells can be used as important indexes for early diagnosis, monitoring and prognosis of tumors, and the exosomes and circulating tumor cells become research objects of current liquid biopsy.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the background art and providing a timely detection platform for exosomes.

In order to achieve the above purpose, the utility model provides a timely detection platform for exosomes, which comprises a rack, wherein one side of the top of the rack is provided with a through groove, one side of the top of the rack, which is far away from the through groove, is provided with a storage groove, the top of the rack, which is close to one side of the through groove, is provided with a support mechanism, the bottom of the support mechanism is slidably provided with a rack rod, the outer side of the rack rod is slidably provided with a connecting mechanism, the inner side of the connecting mechanism is fixedly clamped with a bearing, the inner side of the bearing is rotatably connected with a rotating seat, one side of the rotating seat is communicated with an air outlet pipe, the outer side of the air outlet pipe is communicated with a plurality of groups of air nozzles, the outer side of the air outlet pipe is sleeved with a roller, the inner side of the roller is in a cavity arrangement, the inner side of the roller is provided with air holes corresponding to the plurality of groups of air nozzles, the outer side of the roller is provided with a friction mechanism and is jointed with the top of the rack, and one end of the air outlet pipe, which is far away from the bearing, is provided with a soot blowing mechanism.

Preferably, the supporting mechanism comprises a supporting column vertically connected to one side, close to the through groove, of the top of the rack, a cross rod is transversely connected to the top of the supporting column, and the rack rod is slidably connected to the bottom of the cross rod.

Preferably, the connecting mechanism comprises an L-shaped sliding block connected to the frame rod in a sliding manner, the bearing is fixedly clamped on the inner side of the L-shaped sliding block, and a limiting part is arranged inside one side of the L-shaped sliding block.

Preferably, the limiting part comprises a limiting bolt inserted into one side of the L-shaped sliding block in a threaded manner, and the end part of the limiting bolt is attached to the outer wall of the rack rod.

Preferably, the friction mechanism comprises sponge balls which are clamped outside the roller, and the plurality of sponge balls are in rolling contact with the top of the rack.

Preferably, soot blower includes the air pump of fixed mounting at rack one side outer wall, the one end of air pump has the trachea communicating pipe, the one end outside cover that the air pump was kept away from to the trachea is equipped with the snap ring, the cover is rotated in the outside of snap ring and is equipped with the adapter sleeve, the trachea is linked together through adapter sleeve and outlet duct, the rack corresponds logical groove position department fixed mounting and has the collecting hopper.

Compared with the prior art, the utility model discloses following beneficial effect has: through setting up cylinder and friction mechanism, can be so that the cylinder can roll at the top of rack to the outlet duct of inside intercommunication can sweep the dust at rack top when rolling, and the water stain sponge ball that then passes through rolling contact on surface absorbs, can use up at every turn and carry out the clearance of mesa, efficient and facilitate the use.

Through the L-shaped sliding block, the limiting part and the object placing groove, the whole structure can be moved to the inner side of the object placing groove when the rack is not used, and therefore operation of users is not hindered when the rack is used.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of another angle structure of the present invention;

FIG. 3 is a schematic view of the connection between the frame rod and the roller of the present invention;

FIG. 4 is a schematic view of the disassembly between the air outlet pipe and the roller of the present invention;

FIG. 5 is a sectional view of the position-limiting element and the frame rod of the present invention;

FIG. 6 is an enlarged view of the point A in FIG. 3 according to the present invention;

fig. 7 is an enlarged view of the point B in fig. 4 according to the present invention.

In the figure: 1. a support pillar; 2. a liquid collecting hopper; 3. a rack; 4. a cross bar; 5. an air pump; 6. an air tube; 7. a drum; 8. a bearing; 9. a storage groove; 10. an L-shaped slider; 11. a frame bar; 12. a through groove; 13. air holes; 14. a sponge ball; 15. connecting sleeves; 16. a rotating seat; 17. an air tap; 18. an air outlet pipe; 19. a limit bolt; 20. a snap ring.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention more clearly understood, the present invention will be described in further detail with reference to the accompanying drawings and detailed description.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and the present invention is not limited to the specific embodiments disclosed below.

As shown in figures 1-7, the platform for timely detecting exosomes comprises a rack 3, a through groove 12 is arranged on one side of the top of the rack 3, an article placing groove 9 is arranged on one side of the top of the rack 3 away from the through groove 12, a supporting mechanism is arranged on the top of one side of the rack 3 close to the through groove 12, a rack rod 11 is slidably arranged at the bottom of the supporting mechanism, a connecting mechanism is slidably arranged on the outer side of the rack rod 11, a bearing 8 is fixedly clamped on the inner side of the connecting mechanism, a rotating seat 16 is rotatably connected on the inner side of the bearing 8, and one side of the rotating seat 16 is communicated with an air outlet pipe 18, the outer side of the air outlet pipe 18 is communicated with a plurality of groups of air nozzles 17, the outer side of the air outlet pipe 18 is sleeved with the roller 7, the inner side of the roller 7 is arranged in a cavity, the inner side of the roller 7 is provided with air holes 13 corresponding to the plurality of groups of air nozzles 17, the outer side of the roller 7 is provided with a friction mechanism and is attached to the top of the rack 3, and one end, away from the bearing 8, of the air outlet pipe 18 is provided with a soot blowing mechanism.

When the rack 3 is not used, the bearing 8, the roller 7 and other structures can slide on the lower end of the rack rod 11 to the inner side of the storage groove 9 through the connecting mechanism, so that when the rack 3 is used, the use of the rack 3 is not hindered, and the dust on the top of the rack 3 is treated while rolling through the roller 7 by arranging the soot blowing mechanism to convey gas to the gas outlet pipe 18.

The supporting mechanism comprises a supporting column 1 vertically connected to the top of the rack 3 close to one side of the through groove 12, a cross rod 4 is transversely connected to the top of the supporting column 1, and a rack rod 11 is slidably connected to the bottom of the cross rod 4.

Can catch up dust or water stain to leading to groove 12 department through setting up logical groove 12, through setting up support column 1, can be convenient for support the unit mount, horizontal pole 4 is convenient for hack lever 11 and is removed in the bottom to drive cylinder 7 and roll at the top of rack 3.

The connecting mechanism comprises an L-shaped sliding block 10 connected to the frame rod 11 in a sliding mode, the bearing 8 is fixedly clamped on the inner side of the L-shaped sliding block 10, and a limiting part is arranged inside one side of the L-shaped sliding block 10.

The L-shaped slider 10 can be conveniently moved outside the rack bar 11, so that the roller 7 can be conveniently placed in the storage groove 9.

The limiting part comprises a limiting bolt 19 inserted into one side of the L-shaped sliding block 10 in a threaded manner, and the end part of the limiting bolt 19 is attached to the outer wall of the rack rod 11.

The L-shaped slider 10 can be easily moved out of the storage compartment 9 by providing the stopper 19, and can be easily stopped from the outside.

The friction mechanism comprises sponge balls 14 which are clamped outside the roller 7, and the plurality of sponge balls 14 are in rolling contact with the top of the rack 3.

The sponge ball 14 can not only absorb water stain, but also increase friction force with the top of the rack 3, and after rolling, the water stain can be filtered out at the through groove 12.

Soot blowing mechanism includes air pump 5 of fixed mounting at 3 one side outer walls of rack, and the one end of air pump 5 is communicating pipe has trachea 6, and the one end outside cover that air pump 5 was kept away from to trachea 6 is equipped with snap ring 20, and the cover is rotated in the outside of snap ring 20 to be equipped with adapter sleeve 15, and trachea 6 is linked together through adapter sleeve 15 and outlet duct 18, and the corresponding logical groove 12 position department fixed mounting of rack 3 has collecting hopper 2.

Can be convenient for carry the gas of air pump 5 through setting up trachea 6, when combining gaseous roll, the water stain at 3 tops of rack also can be blown to more do benefit to sponge ball 14 and absorb, and can not cause overflowing of water stain when rolling, the water stain accessible that leads to 12 inboards at the last is collected at the collecting hopper 2 that one end set up.

The working principle is as follows: can remove bearing 8 and cylinder 7 to the top of putting thing groove 9 through removing L shape slider 10, thereby use, screw limit bolt 19 and fix overall structure at the top of rack 3, one end promotes hack lever 11 and removes toward support column 1 department, under sponge ball 14's rolling contact, can make cylinder 7 roll at the top of rack 3, start air pump 5, from trachea 6 department delivered gas to the inboard of outlet duct 18, blow gas at the top of rack 3 in gas pocket 13 department of seting up through air cock 17 and the cylinder 7 outside, so that can absorb water stain at rolling sponge ball 14, the dust is then clear away through the air current that air cock 17 carried.

In the present invention, the terms "mounting", "connecting", "fixing" and the like are used in a broad sense, for example, "connecting" may be a fixed connection, a detachable connection, or an integral connection; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

In the description herein, the appearances of the phrases "one embodiment," "some embodiments," "a specific embodiment," or the like, in various places throughout this specification are not necessarily all referring to the same embodiment or example, but rather to the same embodiment or example. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the principles of the present invention may be applied to any other embodiment without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. The timely detection platform for the exosome comprises a rack (3) and is characterized in that a through groove (12) is formed in one side of the top of the rack (3), an article placing groove (9) is formed in one side, far away from the through groove (12), of the top of the rack (3), a supporting mechanism is arranged at the top of one side, close to the through groove (12), of the rack (3), a rack rod (11) is arranged at the bottom of the supporting mechanism in a sliding mode, a connecting mechanism is arranged on the outer side of the rack rod (11) in a sliding mode, a bearing (8) is fixedly clamped on the inner side of the connecting mechanism, a rotating seat (16) is rotatably connected to the inner side of the bearing (8), an air outlet pipe (18) is communicated to one side of the rotating seat (16), a plurality of groups of air nozzles (17) are communicated to the outer side of the air outlet pipe (18), a roller (7) is sleeved on the outer side of the air outlet pipe (18), and the inner side of the roller (7) is in a cavity, the inboard of cylinder (7) all corresponds multiunit air cock (17) and has seted up gas pocket (13), the cylinder (7) outside is provided with friction mechanism and laminates mutually with rack (3) top, the one end that bearing (8) were kept away from in outlet duct (18) is provided with soot blower.

2. A platform for timely detection of exosomes according to claim 1, characterized in that the supporting mechanism comprises a supporting column (1) vertically connected to one side of the top of the gantry (3) near the through slot (12), a cross bar (4) is transversely connected to the top of the supporting column (1), and the frame bar (11) is slidably connected to the bottom of the cross bar (4).

3. The timely detecting platform for exosomes according to claim 1, wherein the connecting mechanism comprises an L-shaped sliding block (10) connected to the frame rod (11) in a sliding manner, the bearing (8) is fixedly clamped at the inner side of the L-shaped sliding block (10), and a limiting part is arranged inside one side of the L-shaped sliding block (10).

4. The timely detection platform for exosomes according to claim 3, wherein the limiting member comprises a limiting bolt (19) inserted into one side of the L-shaped slider (10) in a threaded manner, and the end of the limiting bolt (19) is attached to the outer wall of the frame rod (11).

5. A platform for timely detection of exosomes according to claim 1, wherein the friction mechanism comprises sponge balls (14) which are all clamped outside the roller (7), and a plurality of the sponge balls (14) are all in rolling contact with the top of the rack (3).

6. The timely testing platform for exosomes according to claim 1, characterized in that the soot blowing mechanism comprises an air pump (5) fixedly installed on the outer wall of one side of the rack (3), one end of the air pump (5) is communicated with an air pipe (6), a snap ring (20) is sleeved on the outer side of one end, away from the air pump (5), of the air pipe (6), a connecting sleeve (15) is sleeved on the outer side of the snap ring (20) in a rotating mode, the air pipe (6) is communicated with an air outlet pipe (18) through the connecting sleeve (15), and a liquid collecting hopper (2) is fixedly installed at the position, corresponding to the through groove (12), of the rack (3).