CN214971126U - Transdermal drug delivery device based on respiratory frequency - Google Patents
Transdermal drug delivery device based on respiratory frequency Download PDFInfo
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- CN214971126U CN214971126U CN202120168825.XU CN202120168825U CN214971126U CN 214971126 U CN214971126 U CN 214971126U CN 202120168825 U CN202120168825 U CN 202120168825U CN 214971126 U CN214971126 U CN 214971126U
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- drug delivery
- delivery device
- respiratory frequency
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- heating plate
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Abstract
The utility model relates to a percutaneous drug delivery device based on respiratory frequency, which comprises a drug delivery structure and a control structure, wherein the drug delivery structure and the control structure are connected with a control signal line through a power line; the drug delivery structure is fixed at the position of the big arm of the patient and used for percutaneous drug delivery; the control structure is fixed at the waist and abdomen of a patient, acquires the respiratory frequency and sends a signal for starting the administration structure according to the respiratory frequency. The utility model discloses a transdermal device of dosing based on respiratory frequency can heat and vibrate the medicine through hot plate and vibrating motor's combined action according to respiratory frequency change, promotes the release of percutaneous absorption medicine.
Description
Technical Field
The utility model belongs to the device field of dosing, in particular to percutaneous device of dosing based on respiratory frequency.
Background
During high-intensity exercise or training, the oxygen demand of the body is increased, aerobic metabolism is inhibited, anaerobic glycolysis is enhanced, and lactic acid is accumulated, thereby causing fatigue. For patients needing long-term transdermal administration, the existing transdermal administration preparation can only be pasted on the surface of the skin for a long time, the dosage can not be timely adjusted according to the state of the patients, and the absorption amount of the medicine can not be timely adjusted according to the change of the demand of the organism on oxygen, so as to relieve the hypoxia or fatigue state.
SUMMERY OF THE UTILITY MODEL
To the above problem, the utility model provides a transdermal drug delivery device based on respiratory rate.
A transdermal drug delivery device based on respiratory frequency comprises a drug delivery structure and a control structure, wherein the drug delivery structure and the control structure are connected through a power line and a control signal line;
the drug delivery structure is fixed at the position of the big arm of the patient and used for percutaneous drug delivery;
the control structure is fixed at the waist and abdomen of a patient, collects the respiratory frequency and sends a signal for starting the administration structure according to the respiratory frequency;
the drug delivery structure comprises a percutaneous absorption drug and a heating plate;
the heating plate is used for heating the percutaneous absorption medicine according to the signal of the respiratory frequency;
the percutaneous absorption medicine is attached to the upper arm of a patient for administration.
Further, the control structure comprises a respiration sensor, a power source and a controller;
the power supply is used for providing micro current for the drug administration structure, the respiration sensor and the controller;
the respiration sensor is used for sensing the abdominal respiration frequency and converting the respiration frequency into an electric signal;
the controller is used for controlling the opening or closing of the administration structure according to the electric signal of the respiratory frequency.
Further, the drug delivery structure further comprises a drug delivery shell, the bottom of the drug delivery shell is in an arc shape attached to the large arm, and the percutaneous absorption drug is located on the outer side of the bottom of the drug delivery shell.
Further, the heating plate is flatly arranged at the bottom of the drug administration shell.
Further, the heating plate is connected with a controller through a control signal line.
Further, the heating plate is a silicon rubber heating plate.
Further, the structure of dosing still includes vibrating motor, vibrating motor fixes in the shell bottom outside of dosing.
Further, the vibration motor is connected with a power supply through a power line.
Further, the medicine feeding structure further comprises a temperature sensor, the temperature sensor is fixed inside the medicine feeding shell and connected with the controller through a temperature control signal line, and the temperature sensor is used for sending heating plate heating signals to the controller.
The utility model discloses a transdermal device of dosing based on respiratory frequency can heat and vibrate the medicine through hot plate and vibrating motor's combined action according to respiratory frequency change, promotes the release of percutaneous absorption medicine. Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by the practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 shows a schematic view of a transdermal drug delivery device according to an embodiment of the present invention;
figure 2 shows a schematic view of the interior of a drug delivery structure according to an embodiment of the present invention;
fig. 3 shows a schematic control structure according to an embodiment of the present invention.
Description of the drawings: 1. a drug delivery housing; 2. a control signal line; 3. heating plates; 4. a power line; 5. a temperature sensor; 6. a vibration motor; 7. a power source; 8. a controller; 9. the drug is absorbed through the skin.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention are clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The utility model relates to a percutaneous device of dosing based on respiratory rate, the unable self-regulation medicament dosage of current device, and to respiratory rate patient under very fast or motion state, need suitably improve the medicament dosage. The investigation shows that the breathing frequency of the normal person is 16-18 times/minute under the resting state. The respiratory rate can be accelerated during hypoxia or exercise, and the inventor designs a transdermal drug delivery device based on the respiratory rate according to the change of the respiratory rate, so that the drug delivery dosage can be increased when the respiratory rate is more than 20 times per minute, and the real-time adjustment of the drug and the safety of patients are effectively ensured.
A respiratory rate based transdermal drug delivery device, as shown in figure 1, includes a drug delivery structure and a control structure. The drug administration structure is pasted and fixed at the position of the big arm of the patient and can be fixed through a binding band. The control structure is arranged at the waist and abdomen of the patient and can be arranged at the waist and abdomen of the patient through a bandage or a buckle or other fixable devices. The drug administration structure and the control structure are connected through a power line 4 and a control signal line 2 which are covered by safe insulation. By adopting the arrangement, the device can be moved along with the patient while ensuring continuous administration, and the action of the patient can not be hindered.
As shown in fig. 2, the control structure includes a respiration sensor, a power supply 7, and a controller 8.
The power supply 7 is used to provide micro-current to the drug delivery structure, the respiration sensor and the controller 8. The power 7 can be common disposable cylindric battery, also can be rechargeable lithium cell, can keep the battery of the sustainable power supply of small size all can, and power 7 sets up in the control structure outside, fixes power 7 on the control structure casing through detachable fixed plate.
The respiration sensor is arranged on the outer side of the control structure shell close to one side of the human body, is positioned between the waist of the human body and is attached to the abdomen of the human body, and is used for sensing the respiration frequency of the abdomen. The signal processor of the respiration sensor is arranged inside the control structure shell and converts the respiration frequency into an electric signal. The respiration sensor is connected with the controller 8 and transmits the electrical signal of the respiration frequency to the controller 8.
The controller 8 is used for controlling the opening or closing of the dosing structure according to the electrical signal of the respiratory frequency, and when the respiratory frequency is more than 20 times/minute and the electrical signal of the respiratory frequency exceeds a threshold value, the controller 8 can open the dosing structure.
As shown in fig. 3, the administration structure includes an administration case 1, a percutaneous absorption drug 9, a heating plate 3, a temperature sensor 5, a vibration motor 6, and a temperature sensor 5.
The bottom of the administration shell 1 adopts a cambered surface design, so that the administration shell can be attached to a large arm as much as possible. The percutaneous absorption medicine 9 is positioned outside the bottom of the administration shell 1, the medicine release surface of the percutaneous absorption medicine 9 is attached to the upper arm, and the percutaneous absorption medicine 9 can be fixed outside the bottom of the administration shell 1 by mounting modes such as adhesion, clamping and the like. And meanwhile, the bottom of the drug administration shell 1 is made of metal materials, so that heat conduction and vibration transmission are facilitated.
The heating plate 3, the temperature sensor 5 and the vibrating motor 6 are all installed inside the drug administration shell 1 and fixed on the inner side of the bottom of the drug administration shell 1.
The 3 tiling settings of hot plate are in 1 bottoms of shell of dosing, fix in 1 bottoms of shell of dosing through 3 four corners of hot plate, and 3 areas of hot plate are less than 1 bottoms of shell of dosing, give with the heating of medicine on the widest range.
Specifically, hot plate 3 is the silicone rubber hot plate, can be better with the setting of laminating of 1 bottoms of shell of dosing, and weight is lighter simultaneously, more portable.
The heating plate 3 is connected with the controller 8 through the control signal line 2, and the controller 8 starts the heating plate 3 to generate heat through the control signal line 2. The heating coil heats the percutaneous absorption drug 9 to promote the drug release.
The vibration motor 6 is fixed at the bottom of the drug administration shell 1 and is arranged close to the heating coil, and the vibration part of the vibration motor 6 is arranged close to the bottom of the drug administration shell 1 and is close to the percutaneous absorption drug 9. The vibration motor 6 is connected with a power supply 7 through a power cord 4. The drug delivery shell 1 is driven to vibrate by the vibration of the vibration motor 6, so that the percutaneous absorption drug 9 is vibrated, and the drug release acceleration of the percutaneous absorption drug 9 is realized.
The temperature sensor 5 is fixed inside the drug administration shell 1 and is connected with the bottom of the drug administration shell 1. Temperature sensor 5 is connected with controller 8 through temperature control signal line 2, to 8 real-time transmission heating temperatures of controller, and when the high temperature, controller 8 stops hot plate 3 and vibrating motor 6 work, avoids the high temperature to cause the patient to scald.
Specifically, when the administration temperature reaches 45 ℃, the controller 8 stops the operation of the heating plate 3 and the vibration motor 6.
The utility model discloses a percutaneous device of dosing is greater than 20/timesharing at respiratory rate, fixes in the device and senses respiratory rate's change at the respiratory sensor of waist, gives abdominal controller 8 with signal transmission, and controller 8 is to upper arm administration structure signals, and the heating of hot plate 3 in the administration structure, and vibrating motor 6 works simultaneously, produces local vibration in the medicine position, promotes the release of percutaneous absorption medicine 9. The utility model discloses a percutaneous device of dosing can breathe independently to adjust the dose according to the patient, simple structure portable simultaneously.
Although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.
Claims (9)
1. A transdermal drug delivery device based on respiratory frequency is characterized by comprising a drug delivery structure and a control structure, wherein the drug delivery structure and the control structure are connected with a control signal line (2) through a power line (4);
the drug delivery structure is fixed at the position of the big arm of the patient and used for percutaneous drug delivery;
the control structure is fixed at the waist and abdomen of a patient, collects the respiratory frequency and sends a signal for starting the administration structure according to the respiratory frequency;
the drug delivery structure comprises a percutaneous absorption drug (9) and a heating plate (3);
the heating plate (3) is used for heating the percutaneous absorption medicine (9) according to the signal of the respiratory frequency;
the percutaneous absorption medicine (9) is attached to the upper arm of the patient.
2. A transdermal drug delivery device according to claim 1, characterized in that the control structure comprises a respiration sensor, a power source (7) and a controller (8);
the power supply (7) is used for providing micro current to the drug administration structure, the respiration sensor and the controller (8);
the respiration sensor is used for sensing the abdominal respiration frequency and converting the respiration frequency into an electric signal;
the controller (8) is used for controlling the opening or closing of the administration structure according to the electric signal of the respiratory frequency.
3. The transdermal drug delivery device according to claim 1, characterized in that the drug delivery structure further comprises a drug delivery housing, the bottom of the drug delivery housing (1) is in an arc shape fitting the large arm, and the percutaneous absorption drug (9) is positioned outside the bottom of the drug delivery housing (1).
4. A transdermal drug delivery device according to claim 3, characterized in that the heating plate (3) is arranged flat at the bottom of the drug delivery housing (1).
5. A transdermal drug delivery device according to claim 3, characterized in that the heating plate (3) is connected to a controller (8) via a control signal line (2).
6. A transdermal drug delivery device according to claim 3, characterized in that the heating plate (3) is a silicone rubber heating plate.
7. The transdermal drug delivery device according to claim 1, characterized in that the drug delivery structure further comprises a vibration motor (6), the vibration motor (6) being fixed outside the bottom of the drug delivery housing (1).
8. Transdermal drug delivery device according to claim 7, characterized in that the vibration motor (6) is connected to the power source (7) via a power line (4).
9. A transdermal drug delivery device according to claim 3, characterized in that the drug delivery structure further comprises a temperature sensor (5), the temperature sensor (5) being fixed inside the drug delivery housing (1), the temperature sensor (5) being connected to the controller (8) by a temperature control signal line (2) for sending a heating signal of the heating plate (3) to the controller (8).
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CN202120168825.XU CN214971126U (en) | 2021-01-21 | 2021-01-21 | Transdermal drug delivery device based on respiratory frequency |
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CN202120168825.XU CN214971126U (en) | 2021-01-21 | 2021-01-21 | Transdermal drug delivery device based on respiratory frequency |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112755384A (en) * | 2021-01-21 | 2021-05-07 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Transdermal drug delivery device based on respiratory frequency |
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2021
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112755384A (en) * | 2021-01-21 | 2021-05-07 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Transdermal drug delivery device based on respiratory frequency |
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