CN214908669U - Mechanical loading device for accurately constructing three-dimensional cartilage tissue - Google Patents
Mechanical loading device for accurately constructing three-dimensional cartilage tissue Download PDFInfo
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- CN214908669U CN214908669U CN202120126267.0U CN202120126267U CN214908669U CN 214908669 U CN214908669 U CN 214908669U CN 202120126267 U CN202120126267 U CN 202120126267U CN 214908669 U CN214908669 U CN 214908669U
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- 210000000845 cartilage Anatomy 0.000 title claims abstract description 34
- 230000007246 mechanism Effects 0.000 claims abstract description 24
- 238000005096 rolling process Methods 0.000 claims abstract description 14
- 230000000903 blocking effect Effects 0.000 claims 2
- 230000000149 penetrating effect Effects 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 abstract description 4
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- 210000002414 leg Anatomy 0.000 description 5
- 238000000034 method Methods 0.000 description 5
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- 210000003035 hyaline cartilage Anatomy 0.000 description 3
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- 230000033001 locomotion Effects 0.000 description 2
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- 206010061762 Chondropathy Diseases 0.000 description 1
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- 108010035532 Collagen Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 210000001188 articular cartilage Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
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- 210000001612 chondrocyte Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
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- 230000006378 damage Effects 0.000 description 1
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- 239000003102 growth factor Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
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Abstract
The utility model discloses a mechanics loading device for accurate three-dimensional cartilage tissue that founds, which comprises a platform, the equal fixedly connected with landing leg in four corners of platform bottom, four fixedly connected with bottom plate between the surface of landing leg, run through on the bottom plate and be provided with the incubator, the culture has been placed to the inside of incubator, the top of platform is provided with reciprocal rolling mechanism, the top of bottom plate is provided with pressure adjustment mechanism, and reciprocal rolling mechanism is fixed with the slide rail including fixing at the left riser in platform top and the U template of slip on platform top right side, the front of riser, the utility model relates to a tissue engineering technical field. This a mechanics loading device for accurate three-dimensional cartilage tissue that founds can realize reciprocal roll loading to the culture through the setting of reciprocal rolling mechanism, and degree of automation is high, only needs a driving motor just can accomplish, and the mechanics loading model of the better structure cartilage tissue of ability uses comparatively conveniently.
Description
Technical Field
The utility model relates to a tissue engineering technical field specifically is a mechanics loading device for accurate three-dimensional cartilage tissue that founds.
Background
Cartilage is composed of cartilage tissue and its surrounding perichondrium, and cartilage tissue is composed of chondrocytes, matrix and fibers. Cartilage is classified into hyaline cartilage, elastic cartilage and fibrocartilage according to the fiber components contained in cartilage tissue, and hyaline cartilage is widely distributed and has a typical structure. Cartilage tissue is composed of collagen tissue, a few cells, and 60-80% water, and adult cartilage tissue has no blood vessels or nerves, so that the cartilage tissue has a limited ability to repair itself after injury. Each bone has a cartilage tissue coating at its distal end. These cartilaginous tissues allow friction and impact between bones to be avoided. Since the 90 s of this century, the advent of cartilage tissue engineering has enabled mankind to construct hyaline cartilage in vivo and in vitro by artificial means, providing a promising approach to the repair of articular cartilage defects. Cartilage tissue engineering is a marginal science combining engineering with biomedicine, especially cell biology, and involves 3 basic elements of cells, scaffold materials, and developmental environments including various growth factors.
At present, researchers at home and abroad simulate the stress type of articular cartilage and the influence of the stress type on the cartilage activity to research and study. Knee joint support and movement functions, and synovial fluid is arranged between the far end of the femur and the near end of the tibia, so that cartilage is nourished and the surface of the cartilage is lubricated. Femur distal end and shin bone near-end contact each other, have two kinds of relative motion, one is the roll, one is the slip, and current roll loading device degree of automation is low, uses comparatively troublesome, consequently, the utility model provides a mechanics loading device for accurate three-dimensional cartilage tissue that founds to solve the above-mentioned problem of mentioning.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art, the utility model provides a mechanics loading device for accurate three-dimensional cartilage tissue that founds has solved current roll loading device degree of automation low, uses comparatively trouble problem.
In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: the utility model provides a mechanics loading device for accurate three-dimensional cartilage tissue that founds, includes the platform, the equal fixedly connected with landing leg in four corners of platform bottom, four fixedly connected with bottom plate between the surface of landing leg, it is provided with the incubator to run through on the bottom plate, the culture has been placed to the inside of incubator, the top of platform is provided with reciprocal rolling mechanism, the top of bottom plate is provided with pressure adjustment mechanism.
Preferably, the reciprocating rolling mechanism comprises a vertical plate fixed on the left side of the top of the platform and a U-shaped plate sliding on the right side of the top of the platform, a sliding rail is fixed on the front side of the vertical plate, a sliding strip is connected to the inner wall of the sliding rail in a sliding manner, a driving motor is fixed on the back side of the vertical plate, a driving shaft is fixed on an output shaft of the driving motor, one end of the driving shaft penetrates through the vertical plate and extends to the front of the vertical plate, and a rotary table is fixed on the surface of the driving shaft.
Preferably, the front of riser is rotated through the pivot and is connected with the circle piece, the fixed surface of circle piece has the stirring piece, the front of draw runner is fixed with first push rod, the one end of first push rod runs through the stirring piece and extends to the inside of stirring the piece, the front of stirring the piece runs through the bar groove of seting up with first push rod looks adaptation, the surface of circle piece still is fixed with the pin, the front of carousel is fixed with the second push rod with pin looks adaptation, the front of draw runner is fixed with T type piece, the front of carousel is fixed with the third push rod with T type piece looks adaptation.
Preferably, the right side of the slide bar is fixedly connected with the left side of the U-shaped plate, a fixed shaft is rotatably connected between the two sides of the inner wall of the U-shaped plate, a roller is fixed on the surface of the fixed shaft, and the surface of the roller is in contact with the top of the culture.
Preferably, the pressure adjusting mechanism comprises an adjusting motor fixed on the bottom plate, a connecting block is fixed on the left side of the incubator, and an output shaft of the adjusting motor is fixed with an adjusting screw rod.
Preferably, the top end of the adjusting screw rod penetrates through the connecting block and extends to the upper side of the connecting block, the top end of the adjusting screw rod is rotatably connected with the bottom of the platform, and the surface of the adjusting screw rod is in threaded connection with the inner wall of the connecting block.
Advantageous effects
The utility model provides a mechanics loading device for accurate three-dimensional cartilage tissue that founds. Compared with the prior art, the method has the following beneficial effects:
(1) the mechanical loading device for accurately constructing the three-dimensional cartilage tissue comprises a reciprocating rolling mechanism arranged at the top of a platform, wherein the reciprocating rolling mechanism comprises a vertical plate fixed on the left side of the top of the platform and a U-shaped plate sliding on the right side of the top of the platform, a sliding rail is fixed on the front side of the vertical plate, a sliding strip is connected on the inner wall of the sliding rail in a sliding manner, a driving motor is fixed on the back side of the vertical plate, a driving shaft is fixed on an output shaft of the driving motor, one end of the driving shaft penetrates through the vertical plate and extends to the front side of the vertical plate, a rotary plate is fixed on the surface of the driving shaft, a round block is rotatably connected on the front side of the vertical plate through a rotating shaft, a poking block is fixed on the surface of the round block, a first push rod is fixed on the front side of the sliding strip, one end of the first push rod penetrates through the poking block and extends to the inside of the poking block, a strip-shaped groove matched with the first push rod is formed in the front side of the round block, and a stop rod is further fixed on the surface of the round block, the front of carousel is fixed with the second push rod with pin looks adaptation, the front of draw runner is fixed with T type piece, the front of carousel is fixed with the third push rod with T type piece looks adaptation, the right side of draw runner and the left side fixed connection of U template, it is connected with the fixed axle to rotate between the both sides of U template inner wall, the fixed surface of fixed axle has the cylinder, the surface of cylinder and the top contact of culture, through the setting of reciprocal rolling mechanism, can realize reciprocal rolling loading to the culture, degree of automation is high, only need a driving motor just to accomplish, the mechanics loading model of the cartilage tissue of structure that can be better, it is comparatively convenient to use.
(2) This a mechanics loading device for accurate three-dimensional cartilage tissue that founds, top through at the bottom plate is provided with pressure adjustment mechanism, pressure adjustment mechanism is including fixing the accommodate motor on the bottom plate, the left side of incubator is fixed with the connecting block, accommodate motor's output shaft is fixed with accommodate screw, accommodate screw's top through connection piece and extend to the top of connecting block, accommodate screw's top and the bottom of platform rotate that and be connected, accommodate screw's surface and the inner wall threaded connection of connecting block, setting through pressure adjustment mechanism, be convenient for change the pressure between culture and the cylinder, use the limitation little.
Drawings
FIG. 1 is a front view of the structure of the present invention;
FIG. 2 is a right side view of the structure of the present invention;
fig. 3 is a rear view of the vertical plate structure of the present invention;
fig. 4 is a right sectional view of the incubator structure of the present invention.
In the figure: 1-platform, 2-supporting legs, 3-bottom plate, 4-incubator, 5-culture, 6-reciprocating rolling mechanism, 601-vertical plate, 602-U-shaped plate, 603-sliding rail, 604-sliding bar, 605-driving motor, 606-driving shaft, 607-rotating disc, 608-round block, 609-toggle block, 610-first push rod, 611-strip groove, 612-stop rod, 613-second push rod, 614-T block, 615-third push rod, 616-fixed shaft, 617-roller, 7-pressure adjusting mechanism, 701-adjusting motor, 702-connecting block, 703-adjusting screw rod.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: the utility model provides a mechanics loading device for accurate three-dimensional cartilage tissue that founds, includes platform 1, the equal fixedly connected with landing leg 2 in four corners of platform 1 bottom, fixedly connected with bottom plate 3 between the surface of four landing legs 2, run through on the bottom plate 3 and be provided with incubator 4, culture 5 has been placed to incubator 4's inside, and platform 1's top is provided with reciprocal rolling mechanism 6, and the top of bottom plate 3 is provided with pressure adjustment mechanism 7.
The reciprocating rolling mechanism 6 comprises a vertical plate 601 fixed on the left side of the top of the platform 1 and a U-shaped plate 602 sliding on the right side of the top of the platform 1, a slide rail 603 is fixed on the front of the vertical plate 601, a slide bar 604 is connected to the inner wall of the slide rail 603 in a sliding manner, a driving motor 605 is fixed on the back of the vertical plate 601 and is electrically connected with an external power supply and controlled by a control switch, a driving shaft 606 is fixed on the output shaft of the driving motor 605, one end of the driving shaft 606 penetrates through the vertical plate 601 and extends to the front of the vertical plate 601, a rotating disc 607 is fixed on the surface of the driving shaft 606, a round block 608 is rotatably connected to the front of the vertical plate 601 through a rotating shaft, a poking block 609 is fixed on the surface of the round block 608, a first push rod 610 is fixed on the front of the slide bar 604, one end of the first push rod 610 penetrates through the poking block 609 and extends to the inside of the poking block 609, a strip groove 611 matched with the first push rod 610 is formed on the front of the poking block 609, a stop lever 612 is further fixed on the surface of the round block 608, a second push rod 613 matched with the stop lever 612 is fixed on the front surface of the rotating disc 607, a T-shaped block 614 is fixed on the front surface of the sliding strip 604, a third push rod 615 matched with the T-shaped block 614 is fixed on the front surface of the rotating disc 607, the right side of the sliding strip 604 is fixedly connected with the left side of the U-shaped plate 602, a fixed shaft 616 is rotatably connected between the two sides of the inner wall of the U-shaped plate 602, a roller 617 is fixed on the surface of the fixed shaft 616, and the surface of the roller 617 is in contact with the top of the culture 5.
The pressure adjusting mechanism 7 comprises an adjusting motor 701 fixed on the bottom plate, the adjusting motor 701 is electrically connected with an external power supply and is controlled by a control switch, the three-phase alternating-current asynchronous motor can rotate forward and backward, a connecting block 702 is fixed on the left side of the incubator 4, an output shaft of the adjusting motor 701 is fixed with an adjusting screw rod 703, the top end of the adjusting screw rod 703 penetrates through the connecting block 702 and extends to the upper side of the connecting block 702, the top end of the adjusting screw rod 703 is connected with the bottom of the platform 1 in a rotating mode, and the surface of the adjusting screw rod 703 is in threaded connection with the inner wall of the connecting block 702.
And those not described in detail in this specification are well within the skill of those in the art.
During operation, the driving motor 605 is started, the driving motor 605 rotates clockwise, and then the turntable 607 is driven to rotate clockwise, the T-shaped block 614 is extruded through the third push rod 605, and then the slide bar 604 moves to the right, then the second push rod 613 extrudes the stop lever 612 upwards, and then the stirring block 609 rotates anticlockwise, the first push rod 610 is extruded through the strip-shaped groove 611, so that the slide bar 604 moves to the left, and then the U-shaped plate 602 moves to and fro left, so that the roller 617 extrudes and rolls back and forth at the top of the culture 5, when the pressure between the culture 5 and the roller 617 needs to be adjusted, the adjusting motor 701 is started, the connecting block 702 is rotated through the adjusting screw rod 703, and the lifting of the connecting block 702 is realized, and then the lifting of the incubator 4 can adjust the pressure between the culture 5 and the roller 617.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a mechanics loading device for constructing three-dimensional cartilage tissue accurately, includes platform (1), its characterized in that: the all fixedly connected with landing leg (2) in four corners of platform (1) bottom, four fixedly connected with bottom plate (3) between the surface of landing leg (2), run through on bottom plate (3) and be provided with incubator (4), culture (5) have been placed to the inside of incubator (4), the top of platform (1) is provided with reciprocal rolling mechanism (6), the top of bottom plate (3) is provided with pressure adjustment mechanism (7).
2. The mechanical loading device for accurately constructing three-dimensional cartilage tissue according to claim 1, wherein: the reciprocating rolling mechanism (6) comprises a vertical plate (601) fixed on the left side of the top of the platform (1) and a U-shaped plate (602) sliding on the right side of the top of the platform (1), a sliding rail (603) is fixed on the front face of the vertical plate (601), a sliding strip (604) is connected to the inner wall of the sliding rail (603) in a sliding mode, a driving motor (605) is fixed on the back face of the vertical plate (601), a driving shaft (606) is fixed on an output shaft of the driving motor (605), one end of the driving shaft (606) penetrates through the vertical plate (601) and extends to the front of the vertical plate (601), and a turntable (607) is fixed on the surface of the driving shaft (606).
3. The mechanical loading device for accurately constructing three-dimensional cartilage tissue according to claim 2, wherein: the front surface of the vertical plate (601) is rotatably connected with a round block (608) through a rotating shaft, a poking block (609) is fixed on the surface of the round block (608), a first push rod (610) is fixed on the front surface of the sliding strip (604), one end of the first push rod (610) penetrates through the poking block (609) and extends into the poking block (609), a strip-shaped groove (611) matched with the first push rod (610) is formed in the front surface of the poking block (609) in a penetrating mode, a blocking rod (612) is further fixed on the surface of the round block (608), a second push rod (613) matched with the blocking rod (612) is fixed on the front surface of the rotating disc (607), a T-shaped block (614) is fixed on the front surface of the sliding strip (604), and a third push rod (615) matched with the T-shaped block (614) is fixed on the front surface of the rotating disc (607).
4. The mechanical loading device for accurately constructing three-dimensional cartilage tissue according to claim 2, wherein: the right side of the sliding strip (604) is fixedly connected with the left side of the U-shaped plate (602), a fixed shaft (616) is rotatably connected between the two sides of the inner wall of the U-shaped plate (602), a roller (617) is fixed on the surface of the fixed shaft (616), and the surface of the roller (617) is in contact with the top of the culture (5).
5. The mechanical loading device for accurately constructing three-dimensional cartilage tissue according to claim 1, wherein: the pressure adjusting mechanism (7) comprises an adjusting motor (701) fixed on the bottom plate, a connecting block (702) is fixed on the left side of the incubator (4), and an adjusting screw rod (703) is fixed on an output shaft of the adjusting motor (701).
6. The mechanical loading device for accurately constructing three-dimensional cartilage tissue according to claim 5, wherein: the top end of the adjusting screw rod (703) penetrates through the connecting block (702) and extends to the upper side of the connecting block (702), the top end of the adjusting screw rod (703) is rotatably connected with the bottom of the platform (1), and the surface of the adjusting screw rod (703) is in threaded connection with the inner wall of the connecting block (702).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120126267.0U CN214908669U (en) | 2021-01-18 | 2021-01-18 | Mechanical loading device for accurately constructing three-dimensional cartilage tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120126267.0U CN214908669U (en) | 2021-01-18 | 2021-01-18 | Mechanical loading device for accurately constructing three-dimensional cartilage tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214908669U true CN214908669U (en) | 2021-11-30 |
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ID=79079304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120126267.0U Expired - Fee Related CN214908669U (en) | 2021-01-18 | 2021-01-18 | Mechanical loading device for accurately constructing three-dimensional cartilage tissue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214908669U (en) |
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2021
- 2021-01-18 CN CN202120126267.0U patent/CN214908669U/en not_active Expired - Fee Related
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| GR01 | Patent grant | ||
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Granted publication date: 20211130 |