CN214863511U - Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine - Google Patents

Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine Download PDF

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Publication number
CN214863511U
CN214863511U CN202120717418.XU CN202120717418U CN214863511U CN 214863511 U CN214863511 U CN 214863511U CN 202120717418 U CN202120717418 U CN 202120717418U CN 214863511 U CN214863511 U CN 214863511U
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China
Prior art keywords
liquid
bioreactor
pipe
connecting seat
catheter
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CN202120717418.XU
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Chinese (zh)
Inventor
李少丽
王家福
尹忠良
康斌
李建林
宝鲁德
丁昂俊
李艳丽
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Hangzhou Uben Animal Vaccine Co ltd
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Hangzhou Uben Animal Vaccine Co ltd
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Priority to CN202120717418.XU priority Critical patent/CN214863511U/en
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Abstract

The utility model discloses a pig circovirus 2 type inactivated vaccine bioreactor's drain mechanism, including last catheter, the connecting pipe, connecting seat and lower catheter, the upper end of going up the catheter is equipped with feed liquor interface and play liquid interface, the lower extreme of going up the catheter is equipped with the inside muddy liquid chamber that has spiral channel, the connecting seat is fixed at the bioreactor top and is connected with the bottom of last catheter, bottom in the connecting seat is equipped with the solenoid valve, the lower extreme at the connecting seat is connected to lower catheter, the bottom of catheter rotates down and is connected with a rotatory water conservancy diversion portion, the periphery array of rotatory water conservancy diversion portion has multi-disc paddle and many first body that set up to same direction slope, the bottom of rotatory water conservancy diversion portion still is equipped with a second body, the utility model discloses can reach better stirring effect to solution at the drainage in-process, and the speed of business turn over liquid is very fast.

Description

Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine
Technical Field
The utility model relates to a drain mechanism of a bioreactor for porcine circovirus type 2 inactivated vaccine.
Background
The solution input in the preparation process of the porcine circovirus type 2 inactivated vaccine and the prepared semi-cost solution need to be stirred all the time, but the bioreactor in the prior art is only internally provided with a stirring device, so the stirring is not ideal; and because the solution is viscous, the effluent of the bioreactor in the prior art is in a self-flowing mode, and the solution is slowly led out.
SUMMERY OF THE UTILITY MODEL
The utility model aims to overcome the defects of the prior art and provide a liquid guiding mechanism of a bioreactor for porcine circovirus type 2 inactivated vaccines.
The technical scheme of the utility model is that: a liquid guide mechanism of a bioreactor for porcine circovirus type 2 inactivated vaccine comprises an upper liquid guide pipe, a connecting seat and a lower liquid guide pipe;
the upper end of the upper liquid guide pipe is provided with a liquid inlet interface and a liquid outlet interface, and the lower end of the upper liquid guide pipe is provided with a liquid mixing chamber with a spiral channel inside;
the connecting seat is fixed at the top of the bioreactor and penetrates through the interior of the bioreactor, the connecting pipe is connected to the top of the connecting seat and is connected with the bottom of the upper liquid guide pipe, the bottom in the connecting seat is provided with an electromagnetic valve, and the lower liquid guide pipe is connected to the lower end of the connecting seat;
the bottom of the lower liquid guide pipe is rotatably connected with a rotary flow guide part, a plurality of blades and a plurality of first pipe bodies which are obliquely arranged in the same direction are arrayed on the periphery of the rotary flow guide part, a second pipe body is further arranged at the bottom of the rotary flow guide part, and the second pipe body and the first pipe bodies penetrate through the inside of the rotary flow guide part.
Furthermore, electric valves are arranged at the joint of the liquid inlet interface and the liquid inlet pipe and the joint of the liquid outlet interface and the liquid outlet pipe.
Furthermore, the lower end of the connecting seat is provided with a quick plug, and the top of the lower catheter is plugged in the quick plug.
Furthermore, the upper end of the lower catheter is provided with a contraction end, the contraction end is provided with a port corresponding to the quick-connection plug, and the joint of the contraction end and the lower catheter is in a cone shape.
Preferably, the distance between the bottom of the second pipe body and the bottom in the bioreactor is kept between 1 mm and 10 mm.
Further, an air guide pipe is further arranged on the lower portion of the air inlet connector of the bioreactor, the air guide pipe is located in the bioreactor, the bottom of the air guide pipe is close to the rotary flow guide portion, and the air outlet of the air guide pipe is arranged towards the blades of the rotary flow guide portion.
The utility model has the advantages that: the utility model designs structures which can lead the solution to generate self-stirring effect in the process of passing through at the upper catheter and the lower catheter, and matches with the air duct to drive the rotary flow guiding part to stir in a rotating way, thus having ideal stirring effect to the solution; on the other hand, the utility model discloses the feed liquor all goes on through the thick pipe that comprises last catheter, connecting pipe, connecting seat and lower catheter with going out liquid, and the feed liquor is smooth and easy, and the mode of cooperation gas transmission pressure boost presses out solution again, and it is very fast to go out liquid speed.
Drawings
Fig. 1 is a schematic structural diagram of the present invention;
fig. 2 is a schematic structural view of the rotary diversion part of the present invention.
Detailed Description
The technical solution of the present invention is further specifically described below by way of examples and with reference to the accompanying drawings.
Referring to fig. 1 and 2, a liquid guiding mechanism of a bioreactor for inactivated vaccine against porcine circovirus type 2 comprises an upper liquid guiding tube 1, a connecting tube 2, a connecting seat 3 and a lower liquid guiding tube 4;
the upper end of the upper liquid guide pipe 1 is provided with a liquid inlet interface 6 and a liquid outlet interface 7, the lower end of the upper liquid guide pipe 1 is provided with a liquid mixing chamber 5 with a spiral channel inside, and when the bioreactor 8 is used for feeding liquid or discharging liquid through the upper liquid guide pipe 1, the solution needs to flow through the liquid mixing chamber 5 to generate agitation in the spiral channel so as to be mixed more uniformly;
furthermore, electric valves are arranged at the joint of the liquid inlet interface 6 and the liquid inlet pipe and the joint of the liquid outlet interface 7 and the liquid outlet pipe;
the connecting seat 3 is fixed on the top of the bioreactor 8 and penetrates through the bioreactor 8, the connecting pipe 2 is connected to the top of the connecting seat 3 and is connected with the bottom of the upper liquid guide pipe 1, and the connecting pipe 2 is arranged to avoid an installation space required by the air inlet joint 9 and the air outlet joint 10; the bottom in the connecting seat 3 is provided with an electromagnetic valve 11 for closing or opening the interior of the bioreactor 8, the lower end of the connecting seat 3 is provided with a quick-connection plug 12, the top of the lower catheter 4 is connected to the quick-connection plug 12 in an inserting manner so as to be convenient for the installation or the disassembly and maintenance of the lower catheter 4, the structure of the quick-connection plug 12 has a plurality of mature technical schemes at present, and the detailed description is not provided herein;
the bottom of the lower liquid guide pipe 4 is rotatably connected with a rotary flow guide part 13, a plurality of blades 14 and a plurality of first pipe bodies 15 which are obliquely arranged in the same direction are arrayed on the periphery of the rotary flow guide part 13, a second pipe body 16 is further arranged at the bottom of the rotary flow guide part 13, a distance of 1-10 mm is kept between the bottom of the second pipe body 16 and the bottom in the bioreactor 8, the second pipe body 16 and each first pipe body 15 penetrate through the inside of the rotary flow guide part 13, when a solution is led in or led out from the rotary flow guide part 13, the rotary flow guide part 13 is driven to rotate, and then the blades 14 are driven to stir the liquid in the bioreactor 8, so that a stirring effect is achieved;
in order to further improve the stirring effect of the rotary flow guide part 13, the lower part of the air inlet joint 9 of the bioreactor 8 is also provided with an air duct 17, the air duct 17 is positioned in the bioreactor 8, the bottom of the air duct 17 is arranged close to the rotary flow guide part 13, the air outlet of the air duct 17 is arranged towards the paddle 14 of the rotary flow guide part 13, and when air enters from the air inlet, the air flow impacts the paddle 14 to enable the rotary flow guide part 13 to rotate so as to stir the liquid in the bioreactor 8;
furthermore, the upper end of the lower liquid guide pipe 4 is provided with a contraction end, the contraction end is provided with an interface corresponding to the quick-connection-peg 12, and the joint of the contraction end and the lower liquid guide pipe 4 is in a cone shape, so that the liquid passing through the part can be accelerated when liquid is fed or discharged, and the effect of stirring and mixing the internal solution is achieved.
The utility model discloses a theory of operation is: when liquid is fed, the electric valve at the joint of the liquid outlet port 7 and the liquid outlet pipe is closed, the electric valve at the joint of the liquid inlet port 6 and the liquid outlet pipe is opened, the electromagnetic valve 11 is opened, the air inlet connector 9 is closed, the air outlet connector 10 is opened, the solution is sprayed into the bioreactor 8 through the liquid inlet port 6, the upper liquid guide pipe 1, the connecting pipe 2, the connecting seat 3, the lower liquid guide pipe 4 and the rotary flow guide part 13, and the rotary flow guide part 13 rotates to stir the liquid in the bioreactor 8 in the spraying process;
after the liquid feeding is finished, the two electric valves and the electromagnetic valve 11 are closed, the gap between the gas outlet joint 10 and the gas inlet joint 9 is opened, gas is filled into the bioreactor 8, so that the environment required by the reaction is maintained in the bioreactor 8, and in the gas inlet process, the gas sprayed by the gas inlet pipe pushes the rotary flow guide part 13 to rotate to stir the liquid in the bioreactor 8;
when liquid is discharged, the electric valve at the joint of the liquid outlet port 7 and the liquid outlet pipe is opened, the electric valve at the joint of the liquid inlet port 6 and the liquid outlet pipe is closed, the electromagnetic valve 11 is opened, the gas outlet connector 10 is closed, the gas inlet connector 9 is opened and continuously filled with gas, and liquid in the bioreactor 8 is extruded out by the rotary flow guide part 13, the lower liquid guide pipe 4, the connecting seat 3, the connecting pipe 2 and the upper liquid guide pipe 1.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. The utility model provides a pig circovirus type 2 inactivated vaccine is with drain mechanism of bioreactor which characterized in that: comprises an upper liquid guide pipe, a connecting seat and a lower liquid guide pipe;
the upper end of the upper liquid guide pipe is provided with a liquid inlet interface and a liquid outlet interface, and the lower end of the upper liquid guide pipe is provided with a liquid mixing chamber with a spiral channel inside;
the connecting seat is fixed at the top of the bioreactor and penetrates through the interior of the bioreactor, the connecting pipe is connected to the top of the connecting seat and is connected with the bottom of the upper liquid guide pipe, the bottom in the connecting seat is provided with an electromagnetic valve, and the lower liquid guide pipe is connected to the lower end of the connecting seat;
the bottom of the lower liquid guide pipe is rotatably connected with a rotary flow guide part, a plurality of blades and a plurality of first pipe bodies which are obliquely arranged in the same direction are arrayed on the periphery of the rotary flow guide part, a second pipe body is further arranged at the bottom of the rotary flow guide part, and the second pipe body and the first pipe bodies penetrate through the inside of the rotary flow guide part.
2. The liquid guiding mechanism of the bioreactor for inactivated vaccine against porcine circovirus type 2 according to claim 1, wherein: electric valves are arranged at the joint of the liquid inlet interface and the liquid inlet pipe and the joint of the liquid outlet interface and the liquid outlet pipe.
3. The liquid guiding mechanism of the bioreactor for inactivated vaccine against porcine circovirus type 2 according to claim 2, wherein: the lower end of the connecting seat is provided with a quick plug, and the top of the lower catheter is plugged in the quick plug.
4. The liquid guiding mechanism of the bioreactor for inactivated vaccine against porcine circovirus type 2 according to claim 3, wherein: the upper end of the lower liquid guide pipe is provided with a contraction end, the contraction end is provided with an interface corresponding to the quick-connection connector, and the joint of the contraction end and the lower liquid guide pipe is in a cone shape.
5. The liquid guiding mechanism of the bioreactor for inactivated vaccine against porcine circovirus type 2 according to claim 4, wherein: and a distance of 1-10 mm is kept between the bottom of the second pipe body and the bottom in the bioreactor.
6. The liquid guiding mechanism of the bioreactor for inactivated vaccine against porcine circovirus type 2 according to claim 5, wherein: the air inlet joint lower part of bioreactor still is equipped with an air duct, the air duct is located bioreactor and its bottom is close to rotatory water conservancy diversion portion and sets up, the paddle setting of the gas outlet orientation rotatory water conservancy diversion portion of air duct.
CN202120717418.XU 2021-04-09 2021-04-09 Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine Active CN214863511U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120717418.XU CN214863511U (en) 2021-04-09 2021-04-09 Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120717418.XU CN214863511U (en) 2021-04-09 2021-04-09 Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine

Publications (1)

Publication Number Publication Date
CN214863511U true CN214863511U (en) 2021-11-26

Family

ID=78949160

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202120717418.XU Active CN214863511U (en) 2021-04-09 2021-04-09 Liquid guide mechanism of bioreactor for porcine circovirus type 2 inactivated vaccine

Country Status (1)

Country Link
CN (1) CN214863511U (en)

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