CN214857763U

CN214857763U - Mouse eyeball excision blood sampling device

Info

Publication number: CN214857763U
Application number: CN202023111156.7U
Authority: CN
Inventors: 王利梅; 徐彩苹; 张承月; 高镜池; 李亚婵; 赵颖
Original assignee: Kunming Medical University
Current assignee: Kunming Medical University
Priority date: 2020-12-22
Filing date: 2020-12-22
Publication date: 2021-11-26
Anticipated expiration: 2030-12-22

Abstract

The utility model discloses a mouse eyeball excision device of getting blood, including base, support column one, support column two and fixing base, two spouts have been seted up to the vertical symmetry of fixing base one end, sliding connection has connecting rod three in the spout, the upper end fixedly connected with briquetting of connecting rod three, the lower extreme fixedly connected with of connecting rod three draws the handle, draw fixedly connected with spring four between handle and the fixing base, the fixed slot has been seted up to the outside bottom of spout, the side surface of connecting rod three is seted up flutedly, sliding connection has the fixed block in the recess, fixedly connected with spring two between the inner of fixed block and the recess. The utility model discloses in, carry out dual fixed through briquetting and stripper plate to the mouse head, the stripper plate oppresses the back neck both sides simultaneously and makes mouse eyeball congestion outstanding, changes and takes out, is provided with and struts the device, avoids the mouse to close the eye.

Description

Mouse eyeball excision blood sampling device

Technical Field

The utility model relates to a blood technical field is got in the excision especially relates to a mouse eyeball excision device of getting blood.

Background

Among biological, pharmacological or other medically or zoologically relevant experiments, mice are the most common experimental animals. Biological evaluation by collecting venous blood from experimental mice is a frequent experimental technique. At present, the method for collecting venous blood of a mouse mainly comprises the steps of taking eyeballs of the mouse, cutting off a part of tail of the mouse, collecting blood through the tail vein and the like. Currently, one of the most common mouse venous blood sampling methods in clinical practice is the eyeball picking method, in which the skin of the neck of an animal is grabbed by the left hand, the skin of the eye of the animal is pressed backwards towards the neck as much as possible by the thumb and the forefinger of the left hand, the eye of the animal is congested and protruded, the eyeball is removed by an elbow forceps, the mouse is inverted, and the head of the mouse faces downwards, so that blood flows out.

At present, the existing device for removing and taking blood from mouse eyeballs still has the defects that most of the existing devices for removing and taking blood are troublesome and insecure in fixing the mouse head, and meanwhile, an eyelid opening device is lacked, so that manual operation is needed, the device is very troublesome, blood is not easy to collect, the eyeballs of the mouse are not prominent, and the device is not easy to take.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a: in order to solve the problems, a mouse eyeball extirpation blood taking device is provided.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a blood taking device for removing eyeballs of mice comprises a base, a first supporting column, a second supporting column and a fixed seat, wherein two sliding grooves are longitudinally and symmetrically formed in one end of the fixed seat, a third connecting rod is connected in the sliding grooves in a sliding mode, a pressing block is fixedly connected to the upper end of the third connecting rod, a pull handle is fixedly connected to the lower end of the third connecting rod, a spring IV is fixedly connected between the pull handle and the fixed seat, a fixed groove is formed in the bottom end of the outer side of each sliding groove, a groove is formed in the side surface of the third connecting rod, a fixed block is connected in the groove in a sliding mode, a spring II is fixedly connected between the inner end of the fixed block and the groove, connecting blocks are fixedly connected to the two longitudinal side surfaces of the fixed seat, ejector rods are arranged in the connecting blocks, one ends of the ejector rods extend into the fixed grooves, connecting plates are fixedly connected to the other ends of the ejector rods, and springs III are fixedly connected to the inner surfaces of the connecting plates and the connecting blocks, the other side center of connecting plate fixedly connected with branch, the other end of branch extends to outside and fixedly connected with button.

Further, an empty groove is formed in one side of the upper surface of the fixing seat, a bidirectional screw rod is arranged in the empty groove in a rotating mode, two sides of the bidirectional screw rod are symmetrically in threaded connection with an extrusion plate, a fixing plate is fixedly connected to one longitudinal side face of the fixing seat, a motor is fixedly connected to the upper surface of the fixing plate, and a transmission shaft of the motor is fixedly connected to one end of the bidirectional screw rod.

Further, the last fixed surface of support column one is connected with fixed frame one, the vertical threaded rod one that is provided with in inside of fixed frame one, the upper end of threaded rod one extends to outside and fixedly connected with knob one, threaded rod one surface threaded connection has connecting rod one, the horizontal fixed frame two of one end fixedly connected with that is close support column two of connecting rod one, fixed frame two is inside vertically to be provided with threaded rod two, the one end of threaded rod two extends to outside and fixedly connected with knob two, the surface threaded connection of threaded rod two has connecting rod two, the lower extreme fixedly connected with fixation box of connecting rod two.

Further, the fixed incasement portion center is horizontal fixedly connected with dead lever, the bilateral symmetry sliding connection of dead lever has the slide bar, the upper end outside fixedly connected with connecting rod of slide bar, the outer end of connecting rod extends to outside and fixedly connected with press the clamp plate, the draw-in groove has been seted up to the lower wall of fixed case, the lower extreme of slide bar extends to outside and fixedly connected with through the draw-in groove and struts the piece, fixedly connected with spring one between two slide bars.

Furthermore, the horizontal center fixedly connected with spacing frame of upper surface of fixing base, the one end of fixing base extends to opposite side and fixedly connected with through support column two changes the handle.

Furthermore, the upper surface of the base is fixedly connected with a collecting box, and one side of the collecting box is fixedly connected with a drainage tube.

To sum up, owing to adopted above-mentioned technical scheme, the beneficial effects of the utility model are that:

the utility model discloses in, pass the mouse from spacing frame in, the pull handle is drawn to the lapse, two briquettings compress tightly the mouse ear, open the motor and make two-way screw rod rotate, two stripper plates move to the inboard simultaneously, thereby extrude the mouse back neck, oppression both sides make eyeball congestion, rotatory knob two this moment make the fixed case move to the mouse eyes directly over, rotatory knob one makes the fixed case reach eyes department, loosen the press plate of fixed case both sides, make the opening piece outwards remove and strut the eyelid, can take out the eyeball this moment, take out the back rotation and change and make the mouse face down, aim at the drainage tube in eyes play can collect collecting box with blood, carry out dual fixed through briquetting and stripper plate to the mouse head, stripper plate oppression back neck both sides make mouse eyeball congestion outstanding simultaneously, change and take out, be provided with the device that struts, avoid the mouse to close the eye.

Drawings

Fig. 1 is a schematic view illustrating an overall structure of an enucleation and blood sampling device according to an embodiment of the present invention;

fig. 2 is a schematic view illustrating an internal structure of a chute provided according to an embodiment of the present invention;

fig. 3 is a schematic view illustrating an upper surface structure of a fixing seat according to an embodiment of the present invention;

fig. 4 is a schematic view of a top view structure of a second fixing frame provided according to an embodiment of the present invention;

fig. 5 shows a schematic diagram of an internal structure of a fixing box provided by the embodiment of the present invention.

Illustration of the drawings:

1. a base; 2. a first supporting column; 3. a fixed seat; 301. a chute; 302. fixing grooves; 303. an empty groove; 304. a bidirectional screw; 4. a second supporting column; 5. a first fixing frame; 501. a first threaded rod; 502. a first knob; 6. a first connecting rod; 7. a second connecting rod; 8. a fixed box; 801. fixing the rod; 802. a card slot; 9. a second fixing frame; 901. a second threaded rod; 902. a second knob; 10. a spreader sheet; 11. a slide bar; 12. a connecting rod; 13. a pressing plate; 14. a first spring; 15. briquetting; 16. a third connecting rod; 1601. a groove; 1602. a second spring; 17. a fixed block; 18. pulling a handle; 1801. a fourth spring; 19. connecting blocks; 1901. a top rod; 1902. a third spring; 1903. a connecting plate; 1904. a strut; 1905. a button; 20. a pressing plate; 21. a fixing plate; 2101. a motor; 22. turning a handle; 23. a limiting frame; 24. a collection box; 25. a drainage tube.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

Referring to fig. 1-5, the present invention provides a technical solution: a mouse eyeball extirpation blood taking device comprises a base 1, a first support column 2, a second support column 4 and a fixed seat 3, wherein two sliding grooves 301 are longitudinally and symmetrically formed in one end of the fixed seat 3, a third connecting rod 16 is slidably connected in the sliding grooves 301, a pressing block 15 is fixedly connected to the upper end of the third connecting rod 16, a pull handle 18 is fixedly connected to the lower end of the third connecting rod 16, a spring four 1801 is fixedly connected between the pull handle 18 and the fixed seat 3, a fixing groove 302 is formed in the outer bottom end of the sliding groove 301, a groove 1601 is formed in the side surface of the third connecting rod 16, a fixing block 17 is slidably connected in the groove 1601, a spring two 1602 is fixedly connected between the inner end of the fixing block 17 and the groove 1601, connecting blocks 19 are fixedly connected to the two longitudinal side surfaces of the fixed seat 3, a push rod 1901 is arranged in the connecting blocks 19, one end of the push rod 1901 extends into the fixing groove 302, and a connecting plate 1903 is fixedly connected to the other end of the push rod 1901, a spring three 1902 is fixedly connected to the inner surfaces of the connecting plate 1903 and the connecting block 19, a supporting rod 1904 is fixedly connected to the center of the other surface of the connecting plate 1903, and the other end of the supporting rod 1904 extends to the outside and is fixedly connected with a button 1905.

Specifically, as shown in fig. 3, an empty groove 303 is formed in one side of the upper surface of the fixing base 3, a bidirectional screw 304 is rotatably arranged in the empty groove 303, two sides of the bidirectional screw 304 are symmetrically and threadedly connected with extrusion plates 20, a fixing plate 21 is fixedly connected to one longitudinal side surface of the fixing base 3, a motor 2101 is fixedly connected to the upper surface of the fixing plate 21, and a transmission shaft of the motor 2101 is fixedly connected to one end of the bidirectional screw 304.

Specifically, as shown in fig. 1 and 4, the fixed frame one 5 of last fixed surface of support column one 2, the vertical threaded rod one 501 that is provided with in inside of fixed frame one 5, the upper end of threaded rod one 501 extends to outside and fixedly connected with knob one 502, threaded rod one 501 surperficial threaded connection has connecting rod one 6, connecting rod one 6 transversely is close to the fixed frame two 9 of one end fixedly connected with of support column two 4, fixed frame two 9 is inside vertically to be provided with threaded rod two 901, the one end of threaded rod two 901 extends to outside and fixedly connected with knob two 902, the surperficial threaded connection of threaded rod two 901 has connecting rod two 7, the lower extreme fixedly connected with of connecting rod two 7 fixes the case 8.

Specifically, as shown in fig. 5, a fixing rod 801 is fixedly connected to the center of the inside of the fixing box 8 in a transverse direction, sliding rods 11 are symmetrically and slidably connected to two sides of the fixing rod 801, a connecting rod 12 is fixedly connected to the outer side of the upper end of each sliding rod 11, the outer end of each connecting rod 12 extends to the outside and is fixedly connected with a pressing plate 13, a clamping groove 802 is formed in the lower wall of the fixing box 8, the lower end of each sliding rod 11 extends to the outside and is fixedly connected with a spreading piece 10 through the clamping groove 802, and a first spring 14 is fixedly connected between the two sliding rods 11.

Specifically, as shown in fig. 1, the transverse center of the upper surface of the fixing seat 3 is fixedly connected with a limiting frame 23, and one end of the fixing seat 3 extends to the other side through the second support column 4 and is fixedly connected with a rotating handle 22.

Specifically, as shown in fig. 1, the upper surface of the base 1 is fixedly connected with a collecting box 24, and one side of the collecting box 24 is fixedly connected with a drainage tube 25.

The working principle is as follows: when the mouse fixing device is used, a mouse passes through the limiting frame 23, the pull handle 18 is pulled downwards to enable the connecting rod III 16 to drive the pressing block 15 to move downwards to the bottom surface, the fixing block 17 reaches the fixing groove 302 and is out, the fixing block 17 is popped out and clamped into the fixing groove 302 under the action of the spring II 1602 to complete fixing, the two pressing blocks 15 press ears of the mouse at the moment, the motor 2101 is started to enable the two-way screw 304 to rotate, the two extrusion plates 20 move inwards at the same time to extrude the back neck of the mouse and press the two sides to cause the eyeball to be congested, the rotary knob II 902 enables the threaded rod II 901 to rotate to enable the fixing box 8 to move right above the eyes of the mouse at the moment, the rotary knob I502 enables the threaded rod I501 to rotate to enable the fixing box 8 to reach the eyes, the pressing plates 13 on the two sides of the fixing box 8 are loosened to enable the opening sheet 10 to move outwards to open the eyelids, the eyeball can be taken out, the rotary handle 22 enables the mouse to face downwards after the mouse is taken out, blood is collected into the collection chamber 24 by aligning the drainage tube 25 with the eye.

Claims

1. The utility model provides a mouse eyeball excision device of getting blood, including base (1), support column (2), support column two (4) and fixing base (3), its characterized in that, two spout (301) have been seted up to fixing base (3) one end vertical symmetry, spout (301) internal sliding connection has connecting rod three (16), the upper end fixedly connected with briquetting (15) of connecting rod three (16), the lower extreme fixedly connected with of connecting rod three (16) draws (18), draw fixedly connected with spring four (1801) between (18) and fixing base (3), fixed slot (302) have been seted up to the outside bottom of spout (301), recess (1601) have been seted up to the side surface of connecting rod three (16), internal sliding connection has fixed block (17) in recess (1601), fixedly connected with spring two (1602) between the inner of fixed block (17) and recess (1601), the utility model discloses a fixing base for fixing a car seat, including fixing base (3), connecting block (19) inside be provided with ejector pin (1901), inside the one end of ejector pin (1901) extends to fixed slot (302), the other end fixedly connected with connecting plate (1903) of ejector pin (1901), the inside fixed surface of connecting plate (1903) and connecting block (19) is connected with spring three (1902), the another side center fixedly connected with branch (1904) of connecting plate (1903), the other end of branch (1904) extends to outside and fixedly connected with button (1905).

2. The mouse eyeball extirpation and blood sampling device according to claim 1, wherein a hollow groove (303) is formed in one side of the upper surface of the fixed seat (3), a bidirectional screw (304) is rotatably arranged in the hollow groove (303), two sides of the bidirectional screw (304) are symmetrically and threadedly connected with the extrusion plates (20), a fixed plate (21) is fixedly connected to one longitudinal side of the fixed seat (3), a motor (2101) is fixedly connected to the upper surface of the fixed plate (21), and a transmission shaft of the motor (2101) is fixedly connected to one end of the bidirectional screw (304).

3. The mouse enucleation blood sampling device according to claim 1, the upper surface of the first support pillar (2) is fixedly connected with a first fixing frame (5), a first threaded rod (501) is vertically arranged inside the first fixing frame (5), the upper end of the first threaded rod (501) extends to the outside and is fixedly connected with a first knob (502), the surface of the first threaded rod (501) is in threaded connection with a first connecting rod (6), one end of the first connecting rod (6) which is transversely close to the second supporting column (4) is fixedly connected with a second fixing frame (9), a second threaded rod (901) is longitudinally arranged inside the second fixed frame (9), one end of the second threaded rod (901) extends to the outside and is fixedly connected with a second knob (902), the surface of the second threaded rod (901) is in threaded connection with a second connecting rod (7), the lower end of the second connecting rod (7) is fixedly connected with a fixed box (8).

4. The mouse eyeball extirpation and blood sampling device according to claim 3, wherein a fixing rod (801) is transversely and fixedly connected to the center inside the fixing box (8), slide rods (11) are symmetrically and slidably connected to two sides of the fixing rod (801), a connecting rod (12) is fixedly connected to the outer side of the upper end of each slide rod (11), the outer end of each connecting rod (12) extends to the outside and is fixedly connected with a pressing plate (13), a clamping groove (802) is formed in the lower wall of the fixing box (8), the lower end of each slide rod (11) extends to the outside through the clamping groove (802) and is fixedly connected with a spreading piece (10), and a first spring (14) is fixedly connected between the two slide rods (11).

5. The mouse eyeball extirpation and blood sampling device according to the claim 1 is characterized in that a limiting frame (23) is fixedly connected to the transverse center of the upper surface of the fixed seat (3), one end of the fixed seat (3) extends to the other side through a second supporting column (4) and is fixedly connected with a rotating handle (22).

6. The mouse eyeball extirpation and blood sampling device according to the claim 1 is characterized in that a collecting box (24) is fixedly connected to the upper surface of the base (1), and a drainage tube (25) is fixedly connected to one side of the collecting box (24).