CN214830270U

CN214830270U - Fluorescent quantitative PCR instrument

Info

Publication number: CN214830270U
Application number: CN202121438117.XU
Authority: CN
Inventors: 李秋实; 高苇; 刘伟
Original assignee: Shanghai Pailong Biotechnology Co ltd
Current assignee: Shanghai Pailong Biotechnology Co ltd
Priority date: 2021-06-26
Filing date: 2021-06-26
Publication date: 2021-11-23
Anticipated expiration: 2031-06-26

Abstract

The utility model discloses a fluorescence quantitative PCR appearance, its technical scheme main points are: comprises a PCR instrument body, a side hole is arranged on one side of the PCR instrument body, a moving block is arranged inside the PCR instrument body, the top surface of the moving block is provided with an analysis bin, two sides of the analysis bin are respectively provided with a clamping groove, by arranging the placing hole, a worker places the test tube in the placing hole, starts the heating rod at the moment, heats the heating rod, and has better heat conductivity because the heat conducting block is brass, when the temperature of the heating rod rises, the product in the test tube can be quickly heated, the product can be effectively amplified through the rise of the temperature, the analysis efficiency of workers on the product is improved, by arranging the heating component, the heating component ensures that when the fluorescent probe marks and tracks the product in the test tube, the product analysis deviation caused by external factors can be avoided, and the analysis accuracy is effectively improved.

Description

Fluorescent quantitative PCR instrument

Technical Field

The utility model relates to a fluorescence quantitative PCR appearance technical field, concretely relates to fluorescence quantitative PCR appearance.

Background

The real-time fluorescent quantitative PCR instrument consists of a fluorescent quantitative system and a computer, is used for monitoring the fluorescence of a cyclic process, the computer connected with real-time equipment collects fluorescence data, and the data is displayed in a form of a chart through developed real-time analysis software.

For example, chinese patent publication No. CN210656874U discloses a fluorescence quantitative PCR instrument, in which a heater, a controller and a cooling system are used to control the temperature inside a reaction cell, and the temperature inside the reaction cell is adjusted by means of water bath, so that the temperature inside the reaction cell can be rapidly and uniformly increased/decreased, and the detection efficiency and the accuracy of the detection result can be improved.

SUMMERY OF THE UTILITY MODEL

In view of the problems mentioned in the background, it is an object of the present invention to provide a fluorescence quantitative PCR instrument to solve the problems mentioned in the background.

The above technical purpose of the present invention can be achieved by the following technical solutions:

fluorescence quantitative PCR appearance, including the PCR appearance body, side opening has been seted up to PCR appearance body one side, the inside of PCR appearance body is provided with the movable block, the analysis storehouse has been seted up to the top surface of movable block, and two are in respectively the joint groove has all been seted up to the both sides in analysis storehouse, the inside in analysis storehouse is provided with heating element.

By adopting the technical scheme, the heating assembly is arranged, so that the heating assembly ensures that the fluorescent probe does not cause product analysis deviation due to external factors when the fluorescent probe marks and tracks products in the test tube, and the analysis accuracy is effectively improved.

Preferably, the heating assembly comprises a heat conduction block, the heat conduction block is arranged inside the analysis bin, a plurality of placing holes are formed in the top surface of the heat conduction block, two fixing holes are formed in one side of the analysis bin, heating rods are connected inside the two fixing holes, connecting blocks are connected to two sides of the heat conduction block, the connecting blocks are movably clamped inside the clamping grooves, the heat conduction block is arranged inside the analysis bin through the connecting blocks, and a stabilizing hole is formed in one side of the connecting blocks.

Through adopting above-mentioned technical scheme, place the hole through the setting, the staff places the test tube in the inside of placing the hole, starts the heating rod this moment, and the heating rod begins to heat, because of the heat conduction piece is brass to having better heat conductivity, when the temperature of heating rod rose, made the inside result of test tube can carry out quick intensification, made the result carry out effectual amplification through the rising of temperature, improved the analysis efficiency of staff to the result.

Preferably, a fixing component is arranged inside the stabilizing hole.

Through adopting above-mentioned technical scheme, through setting up fixed subassembly, fixed subassembly makes that the staff can be convenient dismantle and wash the heat conduction piece.

Preferably, the fixing assembly comprises two inner grooves, the two inner grooves are respectively formed in two sides of the inside of the clamping groove, a spring is sleeved inside the stabilizing hole, the two ends of the spring are connected with clamping columns, the two ends, far away from each other, of the clamping columns penetrate through the stabilizing hole and extend to the outside of the connecting block, limiting holes are formed in two sides, far away from each other, of the connecting block and communicated with the stabilizing hole, limiting columns are connected to the outer circle wall surfaces of the two clamping columns, and one ends, far away from the clamping columns, of the limiting columns penetrate through the limiting holes and extend to the outside of the connecting block.

Through adopting above-mentioned technical scheme, through setting up spacing post, the staff holds between the fingers two spacing posts, removes two spacing posts to the both sides that the excircle wall is close to each other, and the spring is in the stress state this moment, and the staff loosens spacing post with connecting block activity joint in the inside of joint groove, and the effort through the spring this moment with joint post activity joint in the inside of inside groove, spacing post makes spacing hole can only remove when removing.

Preferably, the bottom surface of the moving block is provided with a sliding component.

Through adopting above-mentioned technical scheme, through setting up the sliding subassembly, the effectual movable block that has stabilized of sliding subassembly can not produce when the inside of side opening is stretched out and drawn back and is rocked, has avoided overflowing because of the result of rocking of movable block in the test tube.

Preferably, the sliding assembly comprises two sliding blocks, the two sliding blocks are connected to the left side and the right side of the bottom surface of the moving block, supporting blocks are connected to the left side and the right side of the inner bottom surface of the PCR instrument body, the supporting blocks correspond to the sliding blocks, sliding grooves are formed in the top surfaces of the two supporting blocks, and the two sliding blocks are movably clamped inside the two sliding grooves respectively.

Through adopting above-mentioned technical scheme, through setting up the slider, slider activity joint is in the inside of spout, and drive movable block that can be stable slides in the inside of PCR appearance body, and the support through the slider makes the movable block be the parallel state when removing simultaneously and removes, has improved the stability of movable block when removing.

Preferably, the bottom surface of the PCR instrument body is provided with an adjusting component.

Through adopting above-mentioned technical scheme, through setting up adjusting part, adjusting part makes PCR appearance body can carry out the height-adjusting according to the topography when placing.

Preferably, the adjusting assembly comprises a plurality of screw rods, the screw rods are all connected to the bottom surface of the PCR instrument body, the outer circle wall surface of each screw rod is in threaded connection with a support column, one end, far away from the support column, of each screw rod is connected with a stabilizing block, and one side, far away from the support column, of each stabilizing block is connected with an anti-slip pad.

Through adopting above-mentioned technical scheme, through setting up the support column, staff's accessible rotation support column, the height of support column through screw thread regulation PCR appearance body makes the staff adjust the length of support column according to the hole of topography, makes PCR appearance body can be more stable when placing, and the effectual increase support column of slipmat and the frictional force on ground have prevented the slip of PCR appearance body.

To sum up, the utility model discloses mainly have following beneficial effect:

through arranging the placing hole, a worker places the test tube in the placing hole, starts the heating rod at the moment, the heating rod starts to heat, because the heat conducting block is brass to have better heat conductivity, when the temperature of the heating rod is increased, the product in the test tube can be rapidly heated, the product can be effectively amplified through the temperature increase, the analysis efficiency of the worker on the product is improved, through arranging the heating assembly, the heating assembly ensures that the fluorescent probe can not cause deviation of product analysis due to external factors when marking and tracking the product in the test tube, the analysis accuracy is effectively improved, through arranging the sliding block, the sliding block is movably clamped in the sliding groove, the sliding block can be stably driven to slide in the PCR instrument body, and meanwhile, through the support of the sliding block, the moving block can move in a parallel state when moving, the stability of the moving block is improved when the moving block moves.

By arranging the limiting columns, a worker pinches the two limiting columns to move the two limiting columns to two sides of the outer circle wall surface close to each other, the spring is in a stressed state at the moment, the worker movably clamps the connecting block in the clamping groove to loosen the limiting columns, the clamping columns are movably clamped in the inner groove through the acting force of the spring at the moment, the limiting columns enable the limiting holes to only move left and right when moving, the fixing component is arranged, so that workers can conveniently disassemble and clean the heat conducting block, through setting up the support column, staff's accessible rotation support column, the height of support column through screw thread regulation PCR appearance body makes the staff adjust the length of support column according to the hole of topography, makes PCR appearance body can be more stable when placing, and the effectual increase support column of slipmat and the frictional force on ground have prevented the slip of PCR appearance body.

Drawings

Fig. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic view of the chute structure of the present invention;

FIG. 3 is a schematic view of the structure of the clip groove of the present invention;

FIG. 4 is a schematic view of the connecting block structure of the present invention;

fig. 5 is a schematic view of the structure of the moving block in bottom view;

fig. 6 is a schematic view of the bottom view of the support pillar of the present invention.

Reference numerals: 1. a PCR instrument body; 2. a side hole; 3. a moving block; 4. an analysis bin; 5. a clamping groove; 6. a heat conducting block; 7. placing holes; 8. a fixing hole; 9. a heating rod; 10. connecting blocks; 11. a stabilization well; 12. a spring; 13. a clamping column; 14. a limiting hole; 15. a limiting column; 16. a slider; 17. a support block; 18. a chute; 19. a screw; 20. a support pillar; 21. a stabilizing block; 22. a non-slip mat; 23. an inner tank.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1, 2 and 6, the fluorescence quantitative PCR instrument comprises a PCR instrument body 1, the PCR instrument body 1 is of an existing structure and is not described herein, one side of the PCR instrument body 1 is provided with a side hole 2, the side hole 2 is a rectangular through hole, a moving block 3 is arranged inside the PCR instrument body 1, the moving block 3 is of a rectangular structure, the top surface of the moving block 3 is provided with an analysis bin 4, the analysis bin 4 is a rectangular groove, both sides of the analysis bin 4 are provided with clamping grooves 5, the clamping grooves 5 are rectangular grooves, a heating component is arranged inside the analysis bin 4, the bottom surface of the moving block 3 is provided with a sliding component for moving the moving block 3, the bottom surface of the PCR instrument body 1 is provided with an adjusting component for adjusting the supporting angle of the PCR instrument body 1, the adjusting component comprises a screw rod 19, a plurality of screw rods 19 are fixedly installed on the bottom surface of the PCR instrument body 1, and the screw rods 19 are not described herein, the excircle wall thread bush of screw rod 19 is equipped with support column 20, and support column 20 is pipe-shaped structure and inside and has seted up the screw thread, and stabilizing block 21 is connected the one end fixed mounting that support column 20 kept away from screw rod 19 has stabilizing block 21, and stabilizing block 21 is circular block structure, and one side fixed mounting that support column 20 was kept away from to stabilizing block 21 has slipmat 22, and slipmat 22 does not do the perplexing here for existing structure.

Referring to fig. 2, fig. 3, fig. 4 and fig. 5, the sliding assembly includes a sliding block 16, two sliding blocks 16 are fixedly installed on the bottom surface of the moving block 3, the sliding block 16 is a T-shaped block, two supporting blocks 17 are fixedly installed on the inner bottom surface of the PCR instrument body 1, the supporting blocks 17 are rectangular structures, sliding grooves 18 are formed on the top surfaces of the supporting blocks 17, the sliding blocks 18 are T-shaped grooves, the sliding block 16 is movably clamped inside the sliding grooves 18, the heating assembly includes a heat conducting block 6, a heat conducting block 6 is arranged inside the analysis bin 4, the heat conducting block 6 is a brass rectangular structure, a plurality of placing holes 7 are formed on the top surface of the heat conducting block 6, the placing holes 7 are circular through holes, two fixing holes 8 are formed on one side of the analysis bin 4, the fixing holes 8 are circular through holes, a heating rod 9 is fixedly installed inside the fixing holes 8, the heating rod 9 is an existing structure and is not described herein, two connecting blocks 10 are fixedly installed on both sides of the heat conducting block 6, connecting block 10 is circular slot, and connecting block 10 activity joint is in the inside of joint groove 5, and heat conduction piece 6 sets up in the inside of joint groove 5 through connecting block 10, and stabilizer hole 11 has been seted up to one side of connecting block 10, and stabilizer hole 11 is circular through-hole, and the inside of stabilizer hole 11 is provided with fixed subassembly.

Referring to fig. 3 and 4, fixed subassembly includes inside groove 23, inside groove 23 has all been seted up to the inside both sides of joint groove 5, inside groove 23 is the circular recess, the inside movable sleeve of stabilizer hole 11 is equipped with spring 12, spring 12 does not do the repeated description here for existing structure, the equal fixed mounting in both ends of spring 12 has joint post 13, joint post 13 is cylindrical structure, the both ends that two joint posts 13 kept away from each other are passed stabilizer hole 11 and are extended to the outside of connecting block 10, spacing hole 14 has all been seted up to the both sides that two connecting blocks 10 kept away from each other, spacing hole 14 is the arc through-hole, spacing hole 14 is linked together with stabilizer hole 11, the equal fixed mounting in excircle wall of two joint posts 13 has spacing post 15, spacing post 15 is cylindrical structure, the one end that joint post 13 was kept away from to spacing post 15 passes spacing hole 14 and extends to the outside of connecting block 10.

The working principle is as follows: referring to fig. 1-6, by arranging the placing hole 7, a worker places a test tube inside the placing hole 7, and then starts the heating rod 9, the heating rod 9 starts to heat, because the heat conducting block 6 is made of brass, the heat conducting block has good heat conductivity, when the temperature of the heating rod 9 rises, the product inside the test tube can be rapidly heated, the product can be effectively amplified by the rise of the temperature, the analysis efficiency of the product by the worker is improved, by arranging the heating assembly, the heating assembly ensures that when the fluorescence probe marks and tracks the product inside the test tube, the product analysis can not deviate due to external factors, the analysis accuracy is effectively improved, by arranging the sliding block 16, the sliding block 16 is movably clamped inside the sliding groove 18, and the moving block 3 can be stably driven to slide inside the PCR instrument body 1, meanwhile, the moving block 3 moves in a parallel state when moving through the support of the sliding block 16, and the stability of the moving block 3 when moving is improved.

Through arranging the limiting columns 15, an operator pinches the two limiting columns 15 to move the two limiting columns 15 to two sides of the outer circular wall surface close to each other, the spring 12 is in a stressed state, the operator movably clamps the connecting block 10 in the clamping groove 5 to loosen the limiting columns 15, the clamping column 13 is movably clamped in the inner groove 23 through the acting force of the spring 12, the limiting column 15 enables the limiting hole 14 to move only leftwards and rightwards during moving, through arranging the fixing component, the fixing component enables the operator to conveniently disassemble and clean the heat conducting block 6, through arranging the supporting column 20, the operator can rotate the supporting column 20, the height of the PCR instrument body 1 is adjusted through the screw thread of the supporting column 20, the operator can adjust the length of the supporting column 20 according to the depression of the terrain, the PCR instrument body 1 can be more stable when being placed, and the anti-skid pads 22 effectively increase the friction force between the supporting column 20 and the ground, the sliding of the PCR instrument body 1 is prevented.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. Fluorescence quantitative PCR appearance, including PCR appearance body (1), its characterized in that: side opening (2) have been seted up to PCR appearance body (1) one side, the inside of PCR appearance body (1) is provided with movable block (3), analysis storehouse (4) have been seted up to the top surface of movable block (3), and two are in respectively joint groove (5) have all been seted up to the both sides in analysis storehouse (4), the inside in analysis storehouse (4) is provided with heating element.

2. The fluorescence quantitative PCR instrument according to claim 1, characterized in that: the heating assembly comprises a heat conduction block (6), the heat conduction block (6) is arranged inside the analysis bin (4), the top surface of the heat conduction block (6) is provided with a plurality of placing holes (7), two fixing holes (8) are formed in one side of the analysis bin (4), two heating rods (9) are connected inside the fixing holes (8), connecting blocks (10) are connected to the two sides of the heat conduction block (6), the connecting blocks (10) are movably connected inside the clamping grooves (5), the heat conduction block (6) is arranged inside the analysis bin (4) through the connecting blocks (10), and a stabilizing hole (11) is formed in one side of the connecting blocks (10).

3. The fluorescence quantitative PCR instrument according to claim 2, characterized in that: and a fixing component is arranged in the stabilizing hole (11).

4. The fluorescence quantitative PCR instrument according to claim 3, wherein: fixed subassembly includes two inside grooves (23), two inside groove (23) are seted up respectively the inside both sides of joint groove (5), the inside cover of stable hole (11) is equipped with spring (12), the both ends of spring (12) all are connected with joint post (13), the both ends that keep away from each other of joint post (13) all pass stable hole (11) extend to the outside of connecting block (10), two spacing hole (14) have all been seted up to the both sides that keep away from each other of connecting block (10), spacing hole (14) with stable hole (11) are linked together, two the excircle wall of joint post (13) all is connected with spacing post (15), spacing post (15) are kept away from the one end of joint post (13) is passed spacing hole (14) extend to the outside of connecting block (10).

5. The fluorescence quantitative PCR instrument according to claim 1, characterized in that: the bottom surface of the moving block (3) is provided with a sliding component.

6. The fluorescence quantitative PCR instrument according to claim 5, wherein: the sliding assembly comprises two sliding blocks (16), the two sliding blocks (16) are connected to the left side and the right side of the bottom surface of the moving block (3), supporting blocks (17) are connected to the left side and the right side of the inner bottom surface of the PCR instrument body (1), the supporting blocks (17) correspond to the sliding blocks (16), sliding grooves (18) are formed in the top surfaces of the two supporting blocks (17), and the two sliding blocks (16) are movably clamped inside the two sliding grooves (18) respectively.

7. The fluorescence quantitative PCR instrument according to claim 1, characterized in that: the bottom surface of the PCR instrument body (1) is provided with an adjusting component.

8. The fluorescence quantitative PCR instrument according to claim 7, wherein: the adjusting component comprises a plurality of screws (19), the screws (19) are all connected to the bottom surface of the PCR instrument body (1), the outer circle wall surface of each screw (19) is in threaded connection with a support column (20), one end, far away from the support columns (20), of each screw (19) is connected with a stabilizing block (21), and one side, far away from the support columns (20), of each stabilizing block (21) is connected with an anti-skid pad (22).