CN214765075U - Mixing arrangement of colloidal solution - Google Patents

Mixing arrangement of colloidal solution Download PDF

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Publication number
CN214765075U
CN214765075U CN202022985299.4U CN202022985299U CN214765075U CN 214765075 U CN214765075 U CN 214765075U CN 202022985299 U CN202022985299 U CN 202022985299U CN 214765075 U CN214765075 U CN 214765075U
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cylinder
mixing
plate
collagen
colloidal solution
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CN202022985299.4U
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梁小文
孙冰冰
宋德振
张�成
马健
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Beijing Tianxinfu Medical Appliance Co Ltd
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Beijing Tianxinfu Medical Appliance Co Ltd
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Abstract

The application discloses mixing arrangement of colloidal solution, it includes: each mixing cavity comprises a first cylinder, a second cylinder and a piston rod, the inner diameter of the first cylinder is smaller than that of the second cylinder, the piston rod is inserted into one end of the second cylinder, and the other end of the second cylinder is connected with the first cylinder; the first cylinder in one mixing cavity is communicated with the first cylinder in the other mixing cavity to form a first channel. This mixing arrangement can be used for mixing high concentration collagen solution, has improved the mixing efficiency between collagen and other liquid additives greatly, has improved the degree of consistency of mixed product, makes the difficult reproduction gathering of collagen in the mixed product, guarantees the stability of mixed product, has improved the quality of mixed product.

Description

Mixing arrangement of colloidal solution
Technical Field
The application relates to a mixing arrangement of colloidal solution belongs to colloidal solution processing field.
Background
Collagen, as a natural structural protein, has good bioactivity, biodegradability and biocompatibility, and is widely applied to various fields such as food, medicine, tissue engineering, cosmetics and the like. At present, the extraction technology of collagen is mainly an enzymolysis method, and solid collagen is obtained through the procedures of enzymolysis, filtration, concentration, drying and the like. In general, solid collagen is required to be blended with other liquid additives when used, and it is difficult to uniformly mix collagen with other liquid additives because of its characteristics such as large molecular weight, high viscosity, and low solubility.
At present, current collagen mixing apparatus is mostly rotor rotation type mixing apparatus, and rotor rotation type mixing apparatus passes through the rotatory mixed solution that drives of rotor and flows to reach the purpose with mixed solution misce bene. However, when the existing mixing equipment mixes the high-concentration collagen solution, the high-concentration collagen solution is very easy to adhere to the inner wall of the mixing equipment, so that the existing mixing equipment has a mixing blind area, has poor mixing effect and takes a long time, and causes incomplete mixing between the collagen and other liquid additives, thereby affecting the uniformity of the mixed product.
Disclosure of Invention
In order to solve the problem, the application provides a mixing arrangement of colloidal solution, and this mixing arrangement can be used for mixing high concentration collagen solution, has improved the mixing efficiency between collagen and other liquid additives greatly, has improved the degree of consistency of mixed product, makes the difficult reproduction gathering of collagen in the mixed product, guarantees the stability of mixed product, has improved the quality of mixed product.
According to an aspect of the present application, there is provided a mixing device of a colloidal solution, including:
each mixing cavity comprises a first cylinder, a second cylinder and a piston rod, the inner diameter of the first cylinder is smaller than that of the second cylinder, the piston rod is inserted into one end of the second cylinder, and the other end of the second cylinder is connected with the first cylinder; the first cylinder in one mixing cavity is communicated with the first cylinder in the other mixing cavity to form a first channel;
a housing, each mixing chamber mounted inside the housing.
Optionally, the mixing device further comprises a liquid passing plate, the liquid passing plate is provided with a through hole, the first cylinder in one mixing cavity is communicated with the first cylinder in the other mixing cavity through the through hole, and a first channel is formed between the inside of the first cylinder in the one mixing cavity and the inside of the through hole and between the inside of the first cylinder in the other mixing cavity and the inside of the through hole; and/or
The through-hole is including the first linkage segment, second linkage segment and the third linkage segment that connect gradually, the internal diameter of second linkage segment is less than the internal diameter of first linkage segment, the internal diameter of second linkage segment is less than the internal diameter of third linkage segment.
Optionally, the side wall of the first cylinder is inclined inwards from the joint of the first cylinder and the second cylinder to the joint of the first cylinder and the other first cylinder.
Preferably, the angle of inclination is 10-30 °.
More preferably, the angle of inclination is 20 °.
Optionally, the inner wall of the first barrel is provided with an squamous convex rib, and the included angle between the squamous convex rib and the inner wall of the first barrel is 15-30 degrees; and/or
At least four spiral convex ribs are arranged on the inner wall of the through hole.
Preferably, the first cylinder inner wall is provided with an squamous convex rib, and the included angle between the squamous convex rib and the first cylinder inner wall is 20 degrees.
Preferably, the through-hole inner wall evenly is provided with eight heliciform protruding muscle, every the heliciform protruding muscle winds the through-hole inner wall round.
Optionally, the ratio of the inner diameter of the second cylinder to the thinnest inner diameter of the first cylinder is 2-100: 1.
Preferably, the ratio of the inner diameter of the second cylinder to the thinnest inner diameter of the first cylinder is 10-40: 1.
More preferably, the ratio of the inner diameter of the second cylinder to the thinnest inner diameter of the first cylinder is 30: 1.
Optionally, the interior of the second cylinder forms a second channel.
Optionally, the mixing device further comprises a frame, wherein a base is mounted on the frame, and each mixing cavity is mounted on the base; and/or
The liquid passing plate is detachably mounted on the base.
Optionally, the mixing device further comprises a liquid outlet plate, at least one side of the liquid outlet plate is provided with a groove matched with each first cylinder of the mixing cavity, the end of each first cylinder is abutted against the top wall of the corresponding groove, and a liquid outlet hole is formed in the side wall of each groove.
Optionally, the mixing device further comprises a driving assembly, the driving assembly comprises a power mechanism, a first push plate, a second push plate and at least one guide pillar for connecting the first push plate and the second push plate, the mixing cavity is installed between the first push plate and the second push plate, and the power mechanism is used for driving the first push plate to reciprocate and further driving the second push plate to reciprocate so as to drive the piston rod of each mixing cavity to reciprocate; and/or
The power mechanism is arranged on the lower layer of the rack, the rack is provided with a sliding groove, and the first push plate is connected with the power mechanism through the sliding groove.
Optionally, the mixing device further comprises a clamping mechanism, the clamping mechanism comprises a first pressing plate for pressing the second cylinder of one of the mixing cavities and a second pressing plate for pressing the second cylinder of the other mixing cavity, at least one end of each pressing plate is detachably mounted on the base, and the first pressing plate and the second pressing plate are respectively mounted on two sides of the liquid passing plate; and/or
Each pressing plate is provided with a placing groove matched with the second cylinder of the corresponding mixing cavity.
Benefits that can be produced by the present application include, but are not limited to:
1. according to the colloidal solution mixing device, the inner diameter of the first cylinder is smaller than that of the second cylinder, collagen is subjected to extrusion force of the first channel in the reciprocating motion process between the second cylinder and the first channel with the smaller inner diameter, and collagen aggregates are damaged, so that the particle size of the collagen is reduced, the molecular weight is reduced, the mixing efficiency is improved, the collagen and a liquid additive are fully mixed, a more uniform mixed solution is obtained, collagen in a mixed product is prevented from being aggregated again, the stability of the mixed product is ensured, and the quality of the mixed product is improved; in addition, adjacent mixing chamber links to each other through first barrel and forms first passageway, and this first passageway not only can play the connection effect, can provide bigger atress space for collagen simultaneously, further improves the mixing efficiency between collagen and the liquid mixture.
2. According to the colloidal solution mixing device, the liquid passing plate is arranged to connect the first cylinder body of one mixing cavity and the first cylinder body of the other mixing cavity, so that the phenomenon of liquid leakage caused by the fact that the joint of the two opposite first cylinder bodies is broken after pressure is applied can be prevented; in addition, the through holes of the liquid passing plate can also prolong the length of the first channel, provide larger stress space for collagen, and further improve the mixing efficiency between the collagen and the liquid mixture.
3. The application provides a mixing arrangement of colloidal solution, the lateral wall through setting up first barrel is inwards inclined to its junction direction with another first barrel by its junction with the second barrel, can make the piston more smooth and easy push first barrel with collagen from the second barrel in, reduces collagen mixed solution's push resistance.
4. The application provides a mixing arrangement of colloidal solution sets up the protruding muscle of scale through at first barrel inner wall for collagen receives the crushing effect of the protruding muscle of scale when the first barrel of flowing through, has accelerated the decomposition of collagen aggregate, further improves collagen's mixing efficiency, guarantees that the mixed solution that collagen and liquid additive formed is more even.
5. The application provides a mixing arrangement of colloidal solution, through setting up the ratio of the internal diameter of second barrel and the thinnest department internal diameter of first barrel, can reduce the retention of collagen on second barrel inner wall, improves the yield, guarantees the degree of consistency of collagen mixed solution simultaneously.
6. The application provides a mixing arrangement of colloidal solution crosses liquid board demountable installation at the base through setting up to can change for going out the liquid board, thereby can realize going out liquid in batches, improve out liquid efficiency.
7. The application provides a mixing arrangement of colloidal solution through setting up first push pedal, second push pedal and being used for connecting the guide pillar of first push pedal and second push pedal to can drive the piston rod simultaneous movement of multiunit mixing chamber simultaneously, and then mix the solution in the multiunit mixing chamber simultaneously, guarantee that the collagen particle diameter that finally obtains in every group mixing chamber is unanimous, and molecular weight is similar, thereby can improve batch stability, can improve production efficiency simultaneously.
8. According to the colloidal solution mixing device, the first pressing plate used for pressing the second barrel of one mixing cavity and the second pressing plate used for pressing the second barrel of the other mixing cavity are arranged, so that the mixing cavities can be pressed, and the mixing effect is prevented from being influenced by driving the mixing cavities when the pistons are pushed; at least one end through setting up the clamp plate is demountable installation on the base, conveniently dismantles the mixed cavity under the clamp plate to can in time wash or change mixed cavity, guarantee collagen and liquid additive's mixed effect and cleanliness factor.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
fig. 1 is a top view of a mixing device for a colloidal solution according to an embodiment of the present disclosure;
FIG. 2 is a front view of a liquid passing plate according to an embodiment of the present application;
FIG. 3 is a schematic cross-sectional view of a mixing chamber according to an embodiment of the present disclosure;
FIG. 4 is an enlarged view of portion A of FIG. 3;
FIG. 5 is a front view of a liquid outlet plate according to an embodiment of the present application;
FIG. 6 is a schematic cross-sectional view of a mixing chamber according to an embodiment of the present disclosure;
FIG. 7 is an enlarged view of portion B of FIG. 6;
FIG. 8 is a front view of a mixing device for a colloidal solution according to an embodiment of the present application;
fig. 9 is a schematic view of a mixing device for a colloidal solution according to an embodiment of the present invention.
List of parts and reference numerals:
1. a mixing chamber; 11. a first cylinder; 12. a second cylinder; 13. a piston rod; 14. a liquid passing plate; 15. A through hole; 16. scaly convex tendons; 17. a liquid outlet plate; 18. a groove; 19. a liquid outlet hole; 20. a first platen; 21. a second platen; 3. a frame; 31. a base; 32. a sliding groove; 33. a safety shield; 34. a handle; 41. a power mechanism; 42. a first push plate; 43. a second push plate; 44. a first guide post; 45. a second guide post; 46. a flange-type linear bearing; 47. a display screen; 48. an electric box; 49. a power switch; 50. a scram switch; 51. a reset button; 52. the electric box door.
Detailed Description
In order to more clearly explain the overall concept of the present application, the following detailed description is given by way of example in conjunction with the accompanying drawings.
In order that the above objects, features and advantages of the present application can be more clearly understood, the present application will be described in further detail with reference to the accompanying drawings and detailed description. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, however, the present application may be practiced in other ways than those described herein, and therefore the scope of the present application is not limited by the specific embodiments disclosed below.
In addition, in the description of the present application, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", and the like, indicate orientations and positional relationships based on those shown in the drawings, are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present application.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.
In this application, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can include, for example, fixed connections, removable connections, or integral parts; the connection can be mechanical connection, electrical connection or communication; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.
In this application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. In the description herein, reference to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the application. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The mixing device for the cementing solution is suitable for mixing various high-viscosity cementing solutions, such as pectin, collagen and the like, but is not limited to the cementing solutions. The examples of the present application are described by taking the mixed collagen as an example, but are not limited to this product.
Referring to fig. 1 to 9, embodiments of the present application disclose a mixing device of a colloidal solution, including: the mixing device comprises at least two mixing cavities 1, wherein each mixing cavity 1 comprises a first cylinder 11, a second cylinder 12 and a piston rod 13, the inner diameter of the first cylinder 11 is smaller than that of the second cylinder 12, the piston rod 13 is inserted into one end of the second cylinder 12, and the other end of the second cylinder is connected with the first cylinder 11; the first cylinder 11 in one of the mixing chambers 1 communicates with the first cylinder 11 in the other mixing chamber 1 to form a first passage. By arranging each mixing cavity 1 to comprise a first cylinder 11, a second cylinder 12 and a piston rod 13, placing a mixture consisting of collagen and liquid additives into the second cylinder 12 of the previous mixing cavity 1, inserting the piston rod 13 into the second cylinder 12, pushing the piston rod 13, so that the mixture in the second cylinder 12 enters the second cylinder 12 of the next mixing cavity 1 after passing through a first channel, continuously pushing the piston rod 13 in the second cylinder 12 of the next mixing cavity 1, returning the mixture to the second cylinder 12 of the previous mixing cavity 1 after continuously passing through the first channel, and circulating the processes to make the mixture reciprocate between the adjacent mixing cavities 1 until the collagen to be mixed and the liquid additives form a uniform mixture.
In the embodiment, by setting the inner diameter of the first cylinder 11 to be smaller than the inner diameter of the second cylinder 12, collagen is crushed by the extrusion force of the first channel in the reciprocating motion process between the second cylinder 12 and the first channel with the smaller inner diameter, so that the particle size of the collagen is reduced, the molecular weight of the collagen is reduced, the mixing efficiency is improved, the collagen and the liquid additive are fully mixed, and a more uniform mixed solution is obtained, thereby avoiding the collagen in the mixed product from being aggregated again, ensuring the stability of the mixed product, and improving the quality of the mixed product; in addition, adjacent mixing chamber 1 links to each other through first barrel 11 and forms first passageway, and this first passageway not only can play the connection effect, can provide bigger atress space for collagen simultaneously, further improves the mixing efficiency between collagen and the liquid mixture.
Specifically, the amount of collagen treatment is adjusted according to the inner diameters of the first cylinder 11 and the second cylinder 12. Since collagen has a high viscosity and may partially adhere to the inner walls of the first and second cylinders 11 and 12, a proper amount of collagen may be treated according to the inner diameters of the first and second cylinders 11 and 12 in order to ensure the yield of collagen and reduce the molecular weight of collagen, thereby making the mixed solution formed between collagen and the liquid additive more uniform.
Specifically, in order to improve throughput and production efficiency, this mixing arrangement includes multiunit mixing chamber 1, and every group mixing chamber 1 includes two symmetric distribution's mixing chamber 1, and the first barrel 11 in one of them mixing chamber 1 in every group mixing chamber 1 communicates with the first barrel 11 in another mixing chamber 1 to form first passageway. The number of sets of mixing chambers 1 is not limited in this embodiment, and the number of sets of mixing chambers 1 may be set according to the throughput required by actual production. In addition, can be for arranging the relation wantonly between every group mixing chamber 1, this embodiment improves this mixing arrangement's integrated nature for the area of practicing thrift mixing arrangement, parallel arrangement between every group mixing chamber 1. The first cylinder 11 may have any shape, such as a cylindrical shape, a circular truncated cone shape, a rectangular parallelepiped shape, or a square shape, as long as the flow of the collagen and the liquid additive is achieved; the second cylinder 12 may have any shape, for example, a cylindrical shape, a rectangular parallelepiped shape, or a square shape, as long as the piston reciprocates in the second cylinder.
As an embodiment, the mixing device further includes a liquid passing plate 14, the liquid passing plate 14 is provided with a through hole 15, the first cylinder 11 in one mixing cavity 1 is communicated with the first cylinder 11 in the other mixing cavity 1 through the through hole 15, and a first passage is formed between the inside of the first cylinder 11 in the one mixing cavity 1, the inside of the first cylinder 11 in the other mixing cavity 1 and the inside of the through hole 15. The liquid passing plate 14 is arranged to connect one of the mixing cavities 1 with the first cylinder 11 of the other mixing cavity 1, so that the phenomenon of liquid leakage caused by the breakage of the joint of the two opposite first cylinders 11 after pressure is applied can be prevented; in addition, the through holes 15 of the liquid passing plate 14 can also extend the length of the first channel, so as to provide a larger stress space for collagen, and further improve the mixing efficiency between the collagen and the liquid mixture.
In one embodiment, an end of the first cylinder 11 of one mixing chamber 1 abuts against a sidewall of the liquid passing plate 14, and an end of the first cylinder 11 of the other mixing chamber 1 abuts against the other sidewall of the liquid passing plate 14. This mode of setting up need not to pull down mixing chamber 1 when liquid board 14 is crossed in the dismouting, makes things convenient for the dismouting to cross liquid board 14, has improved work efficiency.
As another embodiment, the first cylinder 11 of one mixing cavity 1 is inserted into one side of the through hole 15, the first cylinder 11 of the other mixing cavity 1 is inserted into the other side of the through hole 15, and a silicone ring is arranged between each first cylinder 11 and the side wall of the through hole 15. The arrangement mode can improve the sealing performance of the first channel and prevent the first channel from leaking or collapsing in the mixing process.
As an embodiment, the through hole 15 includes a first connection section, a second connection section and a third connection section, the inner diameter of the second connection section is smaller than that of the first connection section, and the inner diameter of the second connection section is smaller than that of the third connection section. The inner diameter of the second connecting section is smaller than that of the first connecting section and that of the third connecting section, so that the collagen can be further broken, and the mixing efficiency between the collagen and the liquid additive is improved.
In one embodiment, the side wall of the first cylinder 11 is inclined inward from the connection with the second cylinder 12 to the connection with the other first cylinder 1. Because the viscosity of the collagen is high, the resistance when the piston rod 13 pushes the collagen into the first cylinder 11 from the second cylinder 12 is high, so that the side wall of the first cylinder 11 is inclined inwards from the joint of the side wall and the second cylinder 12 to the joint of the side wall and the other first cylinder 11, the piston rod 13 can push the collagen into the first cylinder 11 from the second cylinder 12 more smoothly, and the pushing resistance of the collagen mixed solution is reduced.
Specifically, the side wall of the first barrel 11 is inclined inward by 10-30 ° from the connection with the second barrel 12 to the connection with the other first barrel 11. Preferably, the angle of inclination is 20 °. This mode of setting up can reduce the resistance when the piston pushes collagen into first barrel 11, makes the promotion process more smooth and easy, can guarantee the length of first passageway simultaneously, guarantees the atress area when collagen flows through first passageway promptly, and then makes the collagen particle diameter that finally obtains littleer, molecular weight is lower.
In one embodiment, the inner wall of the first cylinder 11 is provided with scaly ribs 16, and the scaly ribs 16 form an angle of 15-30 degrees with the inner wall of the first cylinder 11. Preferably, the squamous ribs 16 are angled at 20 ° to the inner wall of the first barrel 11. Through setting up scaly protruding muscle 16 at first barrel 11 inner wall for collagen is when the first barrel 11 of flowing through, receives the crushing effect of scaly protruding muscle 16, further improves collagen's mixing efficiency, guarantees that collagen and the mixed solution that the liquid additive formed are more even. In addition, the included angle between the scaly convex ribs 16 and the inner wall of the first cylinder 11 is set to be 20 degrees, the flow resistance of collagen in the first cylinder 11 can be reduced by the setting mode, meanwhile, the crushing effect of the scaly convex ribs 16 on the collagen can be effectively exerted, the finally obtained collagen has smaller particle size and lower molecular weight, and the mixed solution is more uniform, so that the collagen in the mixed product is prevented from being aggregated again, the stability of the mixed product is ensured, and the quality of the mixed product is improved.
Specifically, the present application does not limit the direction of the scaly ribs 16, and the scaly ribs 16 may be oriented toward the second cylinder 12 connected to the first cylinder 11, or may be oriented toward the liquid passing plate 14 connected to the first cylinder 11. Preferably, the scaly ribs 16 of the present embodiment face the second cylinder 12 connected to the first cylinder 11, and this arrangement can further improve the collagen crushing effect of the scaly ribs 16 and improve the mixing efficiency between the collagen and the liquid additive.
In one embodiment, the inner wall of the through hole 15 is provided with at least four spiral ribs. Specifically, eight spiral convex ribs are uniformly arranged on the inner wall of the through hole 15, each spiral convex rib winds the inner wall of the through hole 15 for a circle, namely, the connecting line of the starting point and the ending point of each scaly convex rib is parallel to the bus of the through hole 15. This arrangement enables the mixture formed between the collagen and the liquid additive to smoothly pass through the through-hole 15 along the spiral rib, thereby reducing the pushing resistance.
Specifically, the first cylinder 11, the second cylinder 12, the liquid passing plate 14, the scaly ribs 16 and the spiral ribs are all made of stainless steel. Preferably, in order to ensure the wear resistance and corrosion resistance and reduce the resistance of the piston rod 13 during reciprocating movement and the flow resistance of the collagen mixed solution, the first cylinder 11, the second cylinder 12, the liquid passing plate 14 and the scaly ribs 16 are made of 316 stainless steel.
Specifically, in order to ensure the sealing performance between the piston rod 13 and the inner wall of the second cylinder 12 and avoid polluting the mixed solution in the mixing cavity 1, a silica gel sleeve is sleeved at one end of the piston rod 13 inserted into the second cylinder 12.
Specifically, the ratio of the inner diameter of the second cylinder 12 to the inner diameter of the thinnest part of the first cylinder 11 is 2-100: 1; preferably, the ratio of the inner diameter of the second cylinder 12 to the inner diameter of the thinnest part of the first cylinder 11 is 10-40: 1; more preferably, the ratio of the inner diameter of the second cylinder 12 to the thinnest inner diameter of the first cylinder 11 is 30: 1. This setting mode can reduce the retention of collagen on the 12 inner walls of second barrel, improves the yield, guarantees the degree of consistency of collagen mixed solution simultaneously.
Specifically, the inner diameter of the thinnest part of the first cylinder is 3-5mm, and preferably, the inner diameter of the thinnest part of the first cylinder is 4 mm. The arrangement mode can fully destroy the structure of the collagen aggregate, so that the collagen mixed solution is more uniform.
Specifically, the interior of the second cylinder 12 forms a second channel. Firstly, a mixture of collagen and liquid additives is placed in the second channel on one side, the mixture is extruded into the first channel through the piston rod 13 and then enters the second channel on the other side, the piston rod 13 in the second channel on the other side continuously extrudes the mixture into the first channel, and the steps are repeated in this way to crush the collagen, so that the collagen with smaller particle size and lower molecular weight is obtained.
As an embodiment, the mixing device further comprises a frame 3, a base 31 is mounted on the frame 3, and each mixing chamber 1 is mounted on the base 31. Preferably, each mixing chamber 1 is removably mounted on the base 31. The mixing cavity 1 is detachably arranged on the base 31, and when the interior of the mixing cavity 1 is worn, the mixing cavity can be replaced in time; meanwhile, the mixing chamber 1 can be detached from the base 31 for cleaning, thereby avoiding cleaning dead angles; in addition, the mixing cavity 1 can be reused after being thoroughly cleaned, and the cost is saved.
In one embodiment, the liquid passing plate 14 is detachably mounted on the base 31 for easy cleaning and avoiding dead corners. Specifically, the liquid passing plate 14 may be detachably mounted on the base 31 by any means, such as a bolt, a quick clamp, etc., as long as the liquid passing plate 14 is detachably mounted on the base 31. In this embodiment, the liquid passing plate 14 is mounted on the base 31 by a butterfly bolt.
As an implementation mode, the mixing device further includes a liquid outlet plate 17, at least one side of the liquid outlet plate 17 is provided with a groove 18 matched with the first cylinder 11 of each mixing cavity 1, the end of the first cylinder 11 is abutted against the top wall of the groove 18, and a liquid outlet hole 19 is formed in the side wall of the groove 18. Preferably, one side of the liquid outlet plate 17 is provided with a groove 18 matched with the first cylinder 11 of each mixing cavity 1. After the collagen mixed solution in mixing chamber 1 is mixed evenly, push away the mixed solution in mixing chamber 1 to the mixing chamber 1 of recess one side through piston rod 13 in, then will cross liquid board 14 and dismantle, change into liquid board 17, promote the piston rod 13 in the mixed chamber 1 that is equipped with mixed solution one side, impel mixed solution recess 18, then flow out mixing arrangement through liquid hole 19. Through setting up liquid board 14 demountable installation at base 31 to can change for going out liquid board 17, thereby can realize putting out liquid in batches, improve out liquid efficiency.
Specifically, in order to ensure corrosion resistance and prevent the mixed solution from being retained in the groove 18 and the liquid outlet hole 19, the liquid outlet plate 17 is made of 316 stainless steel.
As an implementation manner, the mixing device further includes a driving assembly, the driving assembly includes a power mechanism 41, a first pushing plate 42, a second pushing plate 43, and at least one guide post for connecting the first pushing plate 42 and the second pushing plate 43, the mixing cavity 1 is installed between the first pushing plate 42 and the second pushing plate 43, and the power mechanism 41 is configured to drive the first pushing plate 42 to reciprocate, and further drive the second pushing plate 43 to reciprocate, so as to drive the piston rod 13 of each mixing cavity 1 to reciprocate. Through setting up first push pedal 42, second push pedal 43 and the guide pillar that is used for connecting first push pedal 42 and second push pedal 43 to can drive the simultaneous movement of piston rod 13 of multiunit mixing cavity 1 simultaneously, and then mix the solution in the multiunit mixing cavity 1 simultaneously, guarantee that the collagen particle diameter that finally obtains is unanimous in every group mixing cavity 1, and molecular weight is similar, thereby can improve batch stability, can improve production efficiency simultaneously.
Specifically, the driving assembly includes two guide posts, namely a first guide post 44 and a second guide post 45, for connecting the first pushing plate 42 and the second pushing plate 43, the first guide post 44 is used for connecting one end of the first pushing plate 42 and one end of the second pushing plate 43, and the second guide post 45 is used for connecting the other end of the first pushing plate 42 and the other end of the second pushing plate 43. The first guide post 44 and the second guide post 45 are arranged, so that the two ends of the first push plate 42 and the second push plate 43 are stressed uniformly and can synchronously reciprocate, the finally obtained collagen in each group of mixing cavities 1 can be ensured to have consistent particle size and similar molecular weight, and the batch stability of the collagen mixed solution is improved.
Specifically, in order to make the first guide post 44 and the second guide post 45 move relative to the frame 3 more smoothly, the first guide post 44 and the second guide post 45 are fixed to the frame 3 by a flange-type linear bearing 46, respectively.
Specifically, the type of the power mechanism 41 is not limited in this embodiment, and may be an air cylinder, a hydraulic cylinder, an electric cylinder, or the like, as long as the piston rod 13 can be driven to linearly reciprocate in the second cylinder 12. Preferably, in order to precisely control the moving speed and the moving distance of the piston rod 13, the power mechanism 41 is an electric cylinder, a driving motor of the electric cylinder is a servo motor, and the electric cylinder converts the rotary motion of the servo motor into a linear motion, thereby driving the first push plate 42 to reciprocate.
In one embodiment, the power mechanism 41 is installed at the lower layer of the frame 3, the frame 3 is provided with a sliding groove 32, and the first push plate 42 is connected with the power mechanism 41 through the sliding groove 32. By installing the power mechanism 41 at the lower layer of the frame 3, the installation space is saved, the integrity of the mixing device is enhanced, and the floor area of the mixing device is reduced.
Specifically, in order to prevent the potential safety hazard generated after the device breaks down in the mixing process, a safety cover 33 is installed on the upper layer of the rack 3, and the safety cover 33 can be made of any material, such as toughened glass, PC, PVC and the like. In order to facilitate the observation of the working process by the worker and the cleaning, the safety cover 33 in the embodiment is made of tempered glass. Preferably, one side of the safety cover 33 is hinged to the frame 3, and the other side opposite thereto is provided with a handle 34 to facilitate opening or closing of the safety cover 33.
As an implementation mode, the mixing device further comprises a clamping mechanism, the clamping mechanism comprises a first pressing plate 20 used for pressing the second cylinder 12 of one mixing cavity 1 and a second pressing plate 21 used for pressing the second cylinder 12 of the other mixing cavity 1, at least one end of each pressing plate is detachably arranged on the base 31, and the first pressing plate 20 and the second pressing plate 21 are respectively arranged on two sides of the liquid passing plate 14. The first pressing plate 20 used for pressing the second barrel 12 of one mixing cavity 1 and the second pressing plate 21 used for pressing the second barrel 12 of the other mixing cavity 1 are arranged, so that the mixing cavities 1 can be pressed, and the mixing effect is prevented from being influenced by driving the mixing cavities 1 when the piston rods 13 are pushed; at least one end through setting up the clamp plate is demountable installation on base 31, conveniently dismantles mixing cavity 1 under the clamp plate to can in time wash or change mixing cavity 1, guarantee collagen and liquid additive's mixed effect and cleanliness factor.
Specifically, one end of each pressure plate is fixedly mounted on the base 31, and the other end is detachably mounted on the base 31. The detachable mounting manner of the other end of the pressure plate on the base 31 is not limited in this embodiment, for example, a bolt, a quick clamp, etc., as long as the other end of the pressure plate can be detachably mounted on the base 31. Preferably, in order to achieve quick detachment and improve working efficiency, the present embodiment presses the other end of the pressure plate against the base 31 by using a quick clamp.
As an embodiment, each platen is provided with an upper resting groove matching the second cylinder 12 of its corresponding mixing chamber 1. Through setting up and every second barrel 12 assorted last standing groove, place second barrel 12 in last standing groove, can prevent that mixing chamber 1 from taking place to rock. The upper placing groove of the present embodiment is an arc-shaped groove matched with the second cylinder 12.
Preferably, in order to further mix the shaking of the chamber 1, a lower placing groove matched with each second cylinder 12 is provided on the base 31, and the second cylinder 12 is clamped by the upper placing groove and the lower placing groove together. The lower placing groove of the present embodiment is an arc-shaped groove matched with the second cylinder 12.
Specifically, in order to ensure the cleanliness and the service life of the blending device, the frame 3, the base 31, the first pressing plate 20, the second pressing plate 21, the first pushing plate 42, the second pushing plate 43, the first guide pillar 44, the second guide pillar 45 and the flange-type linear bearing 46 are all made of 304 stainless steel.
Specifically, the mixing device further comprises a control mechanism, the control mechanism comprises an electric control system, a single chip microcomputer and a display screen 47, the electric control system and the single chip microcomputer are both installed in the electric box 48, and the display screen 47 is installed above the electric box 48. According to actual production requirements, the electric control system controls the speed of the power mechanism 41 for driving the piston rod 13 to reciprocate and the reciprocating times, so that the collagen mixed solution with the particle size meeting the requirements is obtained. The single chip microcomputer is connected with the electric control system and used for storing parameters when the power mechanism 41 drives the piston rod 13 to do reciprocating motion so as to ensure that the uniformity of each batch of mixed collagen solution is consistent and the quality is more stable. Preferably, the display screen 47 is a touch screen, and an operation instruction of the electronic control system can be input through touch operation, so that various operation parameters are more visualized.
Specifically, the electric box 48 is further provided with a power switch 49, an emergency stop switch 50, and a reset button 51. Pressing the power switch 49 energizes the mixing device; when an emergency occurs during the operation of the mixing device, the emergency stop switch 50 can be pressed at any time to stop the operation of the mixing device; the reset button 51 can reset the first push plate 42, the second push plate 43, the first guide post 44 and the second guide post 45 to the initial positions.
Preferably, a door 52 is provided on one side of the electric box 48 for electrical safety and easy access.
Example 2
Producing mixing chambers 1 of different models, respectively changing the inner diameter of a first cylinder 11 of the mixing chamber 1, the ratio of the inner diameters of a second cylinder 12 and the first cylinder 11, the angle of the side wall of the first cylinder 11 inclining inwards from the joint of the first cylinder 11 and the second cylinder 12 to the joint of the first cylinder 11 and another first cylinder 11, the angle of the scaly convex rib 16 and the inner wall of the first cylinder 11 (the scaly convex rib 16 faces the second cylinder 12 connected with the first cylinder 11), and the rest structures are the same, and mixing the obtained different mixing chambers 1 for the same batch of collagen for the same time, and the rest test conditions are the same, so as to obtain the particle size of the collagen mixed solution and the pushing resistance of the piston rod 13, wherein the test results are shown in table 1:
TABLE 1
Figure DEST_PATH_GDA0003297383900000151
Figure DEST_PATH_GDA0003297383900000161
From the results of table 1, when the inner diameter of the thinnest part of the first cylinder is 4mm, the ratio of the inner diameters of the second cylinder and the first cylinder is 30:1, the angle of the side wall of the first cylinder 11 from the joint of the first cylinder and the second cylinder 12 to the joint of the first cylinder and the other first cylinder 11 is 20 degrees, the included angle between the scaly convex rib and the inner wall of the first cylinder is 20 degrees, the finally obtained collagen particle size is 650nm, and the pushing resistance is 10N; when the inclination angle of the first cylinder is smaller than 10 degrees and the included angle between the scaly convex rib and the inner wall of the first cylinder is larger than 30 degrees, the pushing resistance of the piston rod 13 is larger, the damage to a machine is serious, and the particle size reduction of collagen is not obvious; when the inclination angle of the first cylinder is larger than 30 degrees and the included angle between the scaly convex rib and the inner wall of the first cylinder is smaller than 15 degrees, the particle size change is small and the mixing effect is poor.
In addition, the same batch of collagen was mixed for the same time using a rotor-rotating mixing device, and the remaining test conditions were the same, to obtain a collagen mixed solution having a particle size of 1050 nm.
The embodiments in the present specification are described in a progressive manner, and the same and similar parts among the embodiments are referred to each other, and each embodiment focuses on the differences from the other embodiments. In particular, for the system embodiment, since it is substantially similar to the method embodiment, the description is simple, and for the relevant points, reference may be made to the partial description of the method embodiment.
The above description is only an example of the present application and is not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.

Claims (10)

1. A mixing device for a colloidal solution, comprising: the mixing cavity comprises a first cylinder, a second cylinder and a piston rod, the inner diameter of the first cylinder is smaller than that of the second cylinder, the piston rod is inserted into one end of the second cylinder, and the other end of the second cylinder is connected with the first cylinder; the first cylinder in one mixing cavity is communicated with the first cylinder in the other mixing cavity to form a first channel.
2. The mixing device of colloidal solution as defined in claim 1, further comprising a liquid passing plate having a through hole, wherein the first cylinder in one mixing chamber is communicated with the first cylinder in the other mixing chamber through the through hole, and a first channel is formed between the inside of the first cylinder in one mixing chamber, the inside of the first cylinder in the other mixing chamber and the inside of the through hole; and/or
The through-hole is including the first linkage segment, second linkage segment and the third linkage segment that connect gradually, the internal diameter of second linkage segment is less than the internal diameter of first linkage segment, the internal diameter of second linkage segment is less than the internal diameter of third linkage segment.
3. The mixing device of colloidal solution as defined in claim 1 or 2, wherein the side wall of the first cylinder is inclined inward from the junction with the second cylinder to the junction with the other first cylinder.
4. The mixing device of the colloidal solution as described in claim 2, wherein the first cylinder inner wall is provided with scaly ribs, and the scaly ribs form an angle of 15-30 ° with the first cylinder inner wall; and/or
At least four spiral convex ribs are arranged on the inner wall of the through hole.
5. The mixing device of colloidal solution according to claim 1 or 2, characterized in that the ratio of the inner diameter of said second cylinder to the narrowest point of said first cylinder is 2-100: 1.
6. the mixing device of colloidal solution as defined in claim 1 or 2, wherein the inside of the second cylinder forms a second channel.
7. The mixing device of colloidal solution as defined in claim 2, further comprising a frame on which a base is mounted, each mixing chamber being mounted on said base; and/or
The liquid passing plate is detachably mounted on the base.
8. The mixing device of colloidal solution as defined in claim 7, further comprising a liquid outlet plate, wherein at least one side of the liquid outlet plate is provided with a groove matched with the first cylinder of each mixing chamber, the end of the first cylinder abuts against the top wall of the groove, and the side wall of the groove is provided with liquid outlet holes.
9. The mixing device of colloidal solution as defined in claim 7, further comprising a driving assembly, wherein the driving assembly comprises a power mechanism, a first pushing plate, a second pushing plate and at least one guide post for connecting the first pushing plate and the second pushing plate, the mixing chamber is installed between the first pushing plate and the second pushing plate, the power mechanism is used for driving the first pushing plate to reciprocate, and further driving the second pushing plate to reciprocate, so as to drive the piston rod of each mixing chamber to reciprocate; and/or
The power mechanism is arranged on the lower layer of the rack, the rack is provided with a sliding groove, and the first push plate is connected with the power mechanism through the sliding groove.
10. The mixing device of colloidal solution as defined in claim 7, further comprising a clamping mechanism, wherein the clamping mechanism comprises a first pressing plate for pressing the second cylinder of one mixing chamber and a second pressing plate for pressing the second cylinder of the other mixing chamber, at least one end of each pressing plate is detachably mounted on the base, and the first pressing plate and the second pressing plate are respectively mounted on two sides of the liquid passing plate; and/or
Each pressing plate is provided with a placing groove matched with the second cylinder of the corresponding mixing cavity.
CN202022985299.4U 2020-12-11 2020-12-11 Mixing arrangement of colloidal solution Active CN214765075U (en)

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