CN214712944U

CN214712944U - Sectional type medical drug stent

Info

Publication number: CN214712944U
Application number: CN202120585637.7U
Authority: CN
Inventors: 高成; 唐烈; 陆剑锋; 张珊
Original assignee: Polyrey Medical Tech Suzhou Co ltd
Current assignee: Polyrey Medical Tech Suzhou Co ltd
Priority date: 2020-09-30
Filing date: 2021-03-23
Publication date: 2021-11-16
Anticipated expiration: 2031-03-23
Also published as: CN113069674B; CN113069673A; CN113069673B; CN214712943U; CN113069674A

Abstract

The utility model relates to a sectional medical drug stent, which comprises a plurality of stent components and connecting covering films; each bracket assembly comprises an inner fixed film, a plurality of independent brackets and an outer fixed film; the independent bracket is sleeved on the inner fixed film along the axial direction; the independent bracket comprises a coating film and an annular bracket body, and a gap for filling medicines is formed between the coating film and the annular bracket body; the coating film comprises an inner coating film and an outer coating film. The sectional medical drug stent of the utility model can coat the drug in the coating film, thereby avoiding the problem that the drug falls off from the sectional medical drug stent when the sectional medical drug stent is not implanted into the body or in the process of implantation; through setting up the independent support of spaced for the medicine kind of cladding can be according to the different medicine of actual need cladding in each independent support, in addition, connects two adjacent bracket components through connecting the tectorial membrane, so that the use of sectional type medical medicine support is more nimble.

Description

Sectional type medical drug stent

Technical Field

The utility model belongs to the technical field of medical instrument, concretely relates to medical medicine support of sectional type for treating pathological change jam.

Background

In the existing pathological change dilation operation, a layer of degradable drug protective film is coated on the surface of an integrally woven stent, drugs are distributed on a high polymer film through a spraying technology, the drug exertion time is concentrated, and the drug supply time is short; and because of the integrity of the film, only one medicine can be sprayed, and different pathologies cannot be treated; in addition, before the operation enters the human body, the sprayed medicine easily falls off, so that the medicine is lost, and the operation effect is influenced.

In addition, in current angioplasty, a one-piece woven stent or a one-piece laser engraved stent is generally used. The problem of insufficient supporting force of the braided bracket exists at present; the use of laser sculpture integral type support lacks the flexibility, and the doctor needs implant a plurality of supports simultaneously according to the difference of blood vessel diameter during the operation, leads to treatment cost height, and the patient is difficult to accept.

Therefore, in order to solve the above technical problems, there is a need to provide a sectional type medical drug stent, which not only can avoid the problem that the drug falls off from the stent before and during the implantation process of the stent, but also can be applied to the blood vessels with large differences in the inner diameters of the blood vessels, so as to increase the flexibility of the stent in use, reduce the number of the blood vessel stents implanted into the body of a patient, reduce the treatment cost, and reduce the burden of the patient.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the technical problem that a medicine is difficult to drop on the sectional type medical medicine support and causes the medicine loss before entering the human body is provided to can be applicable to the medical medicine support of sectional type of the great blood vessel of blood vessel internal diameter difference.

In order to achieve the above purpose, the utility model adopts the technical scheme that:

a segmented medical drug stent having an expanded state and a contracted state, the segmented medical drug stent having an inner diameter in the expanded state that is greater than the inner diameter in the contracted state; the sectional medical drug stent comprises a plurality of stent components and connecting covering films which are respectively and fixedly connected with two adjacent stent components;

each of the bracket assemblies includes:

the inner fixed film is cylindrical and is internally provided with a channel;

the independent brackets are sequentially sleeved on the outer side of the inner fixed film at intervals along the axial direction; each independent bracket comprises a coating film and an annular bracket body arranged in the coating film, a gap is formed between the coating film and the annular bracket body, and the gap is filled with medicines; each coating film comprises an inner coating film and an outer coating film sleeved on the outer side of the inner coating film, the inner coating film is sleeved on the outer side of the inner fixing film, and the annular support body is sleeved on the outer side of the inner coating film;

the outer fixing film is cylindrical and is coated on the plurality of outer coating films; the connecting covering film is fixedly connected with the inner fixing film and/or the outer fixing film.

The utility model, through the integral improvement of the sectional medical drug bracket, on one hand, each independent bracket adopts the coating film to coat the bracket body and the drug in the coating film by arranging a plurality of mutually spaced independent brackets, thereby not only ensuring the support of the independent bracket to the tube cavity, but also being capable of well avoiding the drug from falling off the coating film; on the other hand, the plurality of independent brackets are connected into a whole through the fixing film, so that the sectional type medical drug bracket has good bending performance, and the drug can be further prevented from falling from the sectional type medical drug bracket; on the other hand, the plurality of bracket components are connected through the connecting covering film, so that the sectional medical drug bracket can be suitable for blood vessels with large change of the inner diameter of the blood vessel and angular change such as bifurcation.

According to some specific and preferred embodiments, the drugs filled in the gaps of the plurality of independent stents are the same or different. The invention adopts a plurality of independent brackets, thereby avoiding the limitation that one film can only be sprayed with one drug due to the integrity of the film, and leading the sectional medical drug bracket of the invention to coat different drugs to carry out targeted treatment on different patients and different pathologies.

According to some specific and preferred embodiments, in each independent stent, the drugs are circumferentially arranged on the stent body in a surrounding manner, so that when the stent body is supported on the inner wall of the lumen, the drugs can be better contacted with the inner wall of the lumen, and the time and the distance for the drugs to reach the treatment site are shortened.

According to some specific and preferred embodiments, the stent body has a wavy annular structure, so that the stent body can be well contracted and expanded and can provide a good lumen supporting force.

According to some specific and preferred embodiments, the cross-section of the stent body is circular.

According to some specific and preferred embodiments, the connection covering film, the inner fixing film, the outer fixing film, the covering film and the stent body are made of degradable materials, the degradation speed of the connection covering film is greater than or equal to that of the outer fixing film, the degradation speed of the covering film is greater than that of the stent body, and the degradation speeds of the inner fixing film and the outer fixing film are the same or different. The materials of the connecting covering film, the outer fixing film, the inner fixing film, the covering film and the stent body are selected according to the required degradation time, and the high polymer materials with different degradation times are the existing materials.

According to some specific and preferred embodiments, the stent body is made of a polylactic acid-based polymer or a bioabsorbable magnesium alloy material.

According to some specific and preferred embodiments, the inner fixing film is fixedly connected with the inner envelope film, and the outer fixing film is fixedly connected with the outer envelope film.

According to some specific and preferred embodiments, both axial ends of the inner fixing film are respectively closed with both axial ends of the outer fixing film.

According to some specific and preferred embodiments, both axial ends of the inner coating film are respectively closed with both axial ends of the outer coating film.

According to some specific and preferred embodiments, the inner and outer cover films are of equal width.

According to some specific and preferred embodiments, micropores for releasing the drug are formed on the covering film and the fixing film, respectively, so that a part of the drug can be slowly released from the micropores before the fixing film and the covering film are not degraded, thereby achieving the effect of slow release.

According to some specific and preferred embodiments, when the segmented medical drug stent is in a deployed state, the inner diameters of stent bodies in each stent component are the same or different, and an included angle is formed between every two adjacent stent components.

Further, the inner diameter of each bracket component in the unfolding state is gradually reduced from one end to the other end.

According to the utility model discloses an optimal implementation mode, after a plurality of independent support expansions are fixed, the outer fixed membrane of degradation exposes independent support, the collocation of coating film through different macromolecular material, make degradation speed and order become controllable, simultaneously to release time, the manual arrangement is carried out to the release amount, make the medicine of cladding can carry out the release of timing ration in patient's blood vessel according to actual requirement, and can release the medicine for a long time, play the continuous treatment effect for pathological change position, simultaneously can coat different medicine can be to different patients, different pathology carries out the pertinence treatment, make the medicine release of pathological change department have the maneuverability, through corresponding, the treatment of different pathological changes differentiation, reach the purpose of accurate treatment pathological change, the risk of treatment failure has been reduced, the probability that the patient healed has been improved. And, connect two bracket components through connecting the tectorial membrane, the diameter difference of two bracket components can be great to adapt to the great department of blood vessel diameter difference, improve the flexibility that the medical drug stent of sectional type used, reduce the quantity of implanting the internal vascular support of patient, reduce treatment cost, alleviate patient's burden.

Because of the application of the technical scheme, compared with the prior art, the utility model has the following advantages:

the sectional medical drug stent of the utility model can coat the drug in the coating film, thereby avoiding the problem that the drug falls off from the sectional medical drug stent when the sectional medical drug stent is not implanted into the body or in the process of implantation; moreover, by arranging the independent brackets at intervals, different medicines can be coated in the types of the medicines coated in the independent brackets according to actual needs, so that the medicine release maneuverability of the lesion is higher and more targeted; in addition, two adjacent bracket components are connected through the connecting covering film, so that the sectional type medical drug bracket is more flexible to use and can be suitable for more types of blood vessels.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is a partial perspective view of a preferred embodiment of a single stent assembly of the present invention secured in a vessel by balloon dilatation and with the stent body shown in phantom;

FIG. 2 is a partial perspective view of a segmented medical drug stent according to a preferred embodiment of the present invention secured in a blood vessel by balloon dilatation and showing the structure of the stent body;

FIG. 3 is an exploded view of the preferred embodiment of the present invention;

FIG. 4 is an enlarged view of A in FIG. 3;

FIG. 5 is a schematic structural view of the independent bracket of the preferred embodiment of the present invention with a part of the outer coating film removed;

in the figure: 10. the stent comprises an inner fixed membrane 101, a channel 12, an independent stent 121, a coating membrane 122, a stent body 124, a medicament 1211, an inner coating membrane 1212, an outer coating membrane 14, an outer fixed membrane 130, a stent component 140 and a connecting coating membrane.

Detailed Description

In the following, only certain exemplary embodiments are briefly described. As those skilled in the art will recognize, the described embodiments may be modified in various different ways, all without departing from the spirit or scope of the embodiments of the present invention. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.

In the description of the embodiments of the present invention, it should be understood that the terms "length", "inner", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in fig. 1, which are only used for convenience of description of the embodiments of the present invention and simplification of description, but do not indicate or imply that the device or element in question must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the embodiments of the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present invention, "a plurality" means two or more unless specifically limited otherwise.

In the embodiments of the present invention, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly, e.g., as fixed or detachable connections or as an integral part; the connection can be mechanical connection, electrical connection or communication; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the embodiments of the present invention can be understood by those skilled in the art according to specific situations.

In embodiments of the invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features through another feature not in direct contact. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly above and obliquely above the second feature, or simply meaning that the first feature is at a lesser level than the second feature.

The following disclosure provides many different embodiments or examples for implementing different configurations of embodiments of the invention. In order to simplify the disclosure of embodiments of the present invention, the components and arrangements of specific examples are described below. Of course, they are merely examples and are not intended to limit embodiments of the present invention. Furthermore, embodiments of the present invention may repeat reference numerals and/or reference letters in the various examples for purposes of simplicity and clarity and do not in themselves dictate a relationship between the various embodiments and/or arrangements discussed.

Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

As shown in fig. 1 and fig. 2, the present embodiment provides a sectional medical drug stent, which includes a plurality of stent assemblies 130, and a connection covering film 140 respectively fixedly connected to two adjacent stent assemblies 130; the number of the bracket assemblies 130 can be selected according to the requirement, and for example, the number can be 2, 3, and the like.

As shown in fig. 3, each stent assembly 130 includes an inner fixation membrane 10, a plurality of individual stents 12, and an outer fixation membrane 14.

The internal fixation film 10 is cylindrical, a channel 101 is arranged in the internal fixation film, the balloon can be conveniently installed in the channel 101, and after the sectional type medical drug stent 1 is unfolded, the blood flow can conveniently pass through the channel and the influence on the flow of the blood flow is not easily caused.

As shown in fig. 3 to 5, a plurality of independent brackets 12 are axially sleeved outside the inner fixing film 10, and the plurality of independent brackets 12 are arranged at intervals; each independent bracket 12 comprises a coating film 121 and a bracket body 122 arranged in the coating film 121; a gap is formed between the coating film 121 and the annular bracket body 122 and is used for filling the medicine 124; each coating film 121 comprises an inner coating film 1211 and an outer coating film 1212 sleeved outside the inner coating film 1211, the inner coating film 1211 is sleeved outside the inner fixing film 10 and is fixedly connected with the inner fixing film 10, and the annular support body 122 is sleeved outside the inner coating film 1211.

The outer fixing film 14 is cylindrical, covers the plurality of outer covering films 1212, and is fixedly connected to the outer covering films 1212.

The connection coating 140 may be fixedly connected to the inner fixing film 10, or fixedly connected to the outer fixing film 14, or fixedly connected to both the inner fixing film 10 and the outer fixing film 14.

The coating film 121 of each independent stent 12 can adopt materials with different properties to achieve different degradation times according to requirements, so that the degradation speed and the degradation sequence become controllable, the medicine 124 in the coating film 121 is released in a timed and quantitative manner, the purpose of accurately treating pathological changes is achieved, and a continuous treatment effect is achieved for the pathological change parts. The annular stent body 122 has a high ability to withstand radial pressure. The medicine 124 is arranged in the gap formed by the inner coating 1211 and the outer coating 1212, so that the medicine 124 is prevented from falling off, and the treatment effect is improved. The independent supports 12 are limited and combined through the matching of the inner fixing film 10 and the outer fixing film 14, so that when the medical segmented drug support is implanted, the independent supports 12 can be combined together as required, the independent supports 12 are prevented from moving, the independent supports 12 can accurately reach the lesion part, and the medical segmented drug support is more beneficial to bending by adopting the films to connect the independent supports 12. The inner fixing film 10, the outer fixing film 14 and the annular stent body 122 can be expanded and degraded at a designated time, and the time before the inner fixing film 10 and the outer fixing film 14 are degraded can provide the time for the drug stent to be fixed in the blood vessel for a long time, and the drug stent cannot be influenced when the blood vessel moves and bends.

The utility model discloses preferably medicine 124 establishes on cyclic annular stake body 122 along circumference ring, and medicine 124 distributes evenly, improves treatment effeciency and effect.

In order to improve the expansion of the annular stent body 122 to the blood vessel, the annular stent body 122 can be stabilized in the blood vessel at the same time, and the utility model discloses preferred annular stent body 122 is the wave annular structure.

The cross-section of the preferred annular stent body 122 of the present invention is circular, avoiding damage to the blood vessel.

The utility model discloses the diaxon end of preferred internal fixation membrane 10 seals together with the diaxon end of external fixation membrane 14 respectively, further realizes spacing to a plurality of independent support 12.

The width of the inner wrapping film 1211 is preferably equal to that of the outer wrapping film 1212, the structure is simple, and the stability of the medicine 123 between the inner wrapping film 1211 and the outer wrapping film 1212 is improved.

To further prevent the medicine 123 from falling off, it is preferable that both axial ends of the inner envelope 1211 and both axial ends of the outer envelope 1212 are respectively sealed.

In the present application, the inner covering film 1211 and the outer covering film 1212, the inner covering film 1211 and the inner fixing film 10, the outer covering film 1212 and the outer fixing film 14, and the connection covering film 140 and the inner fixing film 10 and/or the outer fixing film 14 may be fixedly connected by sewing, sealing, or heat pressing.

In the application, the inner fixing film 10, the inner covering film 1211, the stent body 122, the outer covering film 1212, the outer fixing film 14 and the connecting covering film 140 are all made of degradable materials, and the degradation speed of the connecting covering film 140 is greater than or equal to that of the fixing film and greater than that of the covering film and greater than that of the stent body 122, so that the risk that the connecting covering film 140 is dissociated in a blood vessel due to degradation of the fixing film in preference to the connecting covering film 140 is avoided, wherein control of different degradation speeds is realized by selecting high polymer materials with different degradation speeds; the specific degradation rate can be determined according to the actual needs of the patient during treatment.

The utility model discloses preferred cyclic annular stake body 122 adopts polylactic acid class polymer material to make, can degrade by oneself when reaching design life, need not to take out from the blood vessel, but is not restricted to polylactic acid class polymer material, also can make for bio-absorbable nature magnesium alloy material.

When the utility model is used, the sectional medical drug stent is in a contraction state in an initial state, a saccule (not shown in the figure) is arranged in the channel 101 of the internal fixed film 10, and the saccule is provided with an inflatable and air-extracting connecting port; the drug stent 1 enters a human body pathological change blood vessel through a guide wire (not shown in the figure), the saccule is inflated, and the drug stent is then stretched to the unfolding state so that the inner diameter of the drug stent is larger than that of the sectional type medical drug stent in the contraction state; after the balloon is pumped out, the drug stent is fixed at the lesion part; after the drug stent is expanded, a plurality of independent stents 12 are embedded into the vessel wall for fixation after a period of time, and will not fall off even if the vessel moves and contracts, and the inner fixed membrane 10 and the outer fixed membrane 14 are degraded at the design time; the plurality of independent brackets 12 are exposed after the outer fixed film 12 is degraded, and due to the independent arrangement of the plurality of independent brackets 12, the degradation speed and the degradation sequence are controllable by adopting the collocation of different high polymer materials through the plurality of coating films 121, so that different degradation times are achieved; under the action of different degradation times of the plurality of coating films 121, the drugs can be released according to different sequences, different times and different dosages, and different drugs can be matched in each section; the vessel recovers the blocked lumen by the expansion of the plurality of annular stent bodies 122 and the release of the drug 124, and the plurality of annular stent bodies 122 reach the design life and start to degrade by themselves without being taken out.

The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A segmented medical drug stent having an expanded state and a contracted state, the segmented medical drug stent having an inner diameter in the expanded state that is greater than the inner diameter in the contracted state; the sectional type medical drug stent is characterized by comprising a plurality of stent components and connecting covering films which are respectively and fixedly connected with two adjacent stent components;

each of the bracket assemblies includes:

the inner fixed film is cylindrical and is internally provided with a channel;

2. The segmented medical drug stent of claim 1, wherein: the medicines filled in the gaps of the independent brackets are the same or different.

3. The segmented medical drug stent of claim 1, wherein: in each independent stent, the medicines are circumferentially arranged on the stent body in a surrounding manner.

4. The segmented medical drug stent of claim 1, wherein: the connection covering film, the inner fixing film, the outer fixing film, the covering film and the stent body are made of degradable materials, the degradation speed of the connection covering film is greater than or equal to that of the outer fixing film, the degradation speed of the covering film is greater than that of the stent body, and the degradation speeds of the inner fixing film and the outer fixing film are the same or different.

5. The segmented medical drug stent of claim 1, wherein: the stent body is made of polylactic acid polymer or bioabsorbable magnesium alloy material.

6. The segmented medical drug stent of claim 1, wherein: the inner fixed film is fixedly connected with the inner wrapping film, and the outer fixed film is fixedly connected with the outer wrapping film.

7. The segmented medical drug stent of claim 1, wherein: the two shaft ends of the inner fixed film are respectively sealed with the two shaft ends of the outer fixed film.

8. The segmented medical drug stent of claim 1, wherein: the two shaft ends of the inner coating film are respectively sealed with the two shaft ends of the outer coating film; the width of the inner coating film is equal to that of the outer coating film.

9. The segmented medical drug stent of claim 1, wherein: micropores for releasing the medicine are respectively formed on the coating film and the fixed film.

10. The segmented medical drug stent of claim 1, wherein: when the sectional type medical drug stent is in a deployed state, the inner diameters of stent bodies in each stent component are the same or different, and an included angle is formed between every two adjacent stent components.