CN214634438U

CN214634438U - Polypeptide desalination device

Info

Publication number: CN214634438U
Application number: CN202022375098.2U
Authority: CN
Inventors: 夏彬; 何伶杰
Original assignee: Synpeptide Co ltd
Current assignee: Synpeptide Co ltd
Priority date: 2020-10-23
Filing date: 2020-10-23
Publication date: 2021-11-09
Anticipated expiration: 2030-10-23

Abstract

The utility model discloses a polypeptide desalting device, which comprises a box body, wherein a first baffle and a second baffle are sequentially and fixedly arranged in an inner cavity of the box body from top to bottom, a third baffle is fixedly arranged at the bottom of the inner cavity of the box body and at the bottom of the second baffle, a lifting mechanism is arranged at one side of the inner cavity of the box body and at the third baffle, one end of the lifting mechanism penetrates through the third baffle and extends to the outside of the third baffle, a supporting plate is fixedly arranged at the top of the supporting plate, and a bottle body is arranged at the top of the bottle body and communicated with a ring body; the utility model injects the solution into the measuring cylinder through the funnel, the solution enters the filter cylinder through the first pipeline, and the solution is filtered through the filter cylinder; the vacuum pump is used for pumping out the gas in the vacuum box and the bottle body and exhausting the gas to the outside of the box body, so that the inside of the vacuum box and the inside of the bottle body are in a negative pressure state, the speed of the solution is increased when the solution passes through the filter cartridge, and the purpose of increasing the permeation speed is achieved.

Description

Polypeptide desalination device

Technical Field

The utility model relates to a polypeptide desalination equipment technical field specifically is a device of polypeptide desalination.

Background

Polypeptides are compounds formed by the linkage of alpha-amino acids together by peptide bonds, which are also intermediates in the hydrolysis of proteins, and generally peptides contain two to nine amino acids, which are variously referred to according to the number of amino acids in the peptide: the compounds obtained by dehydrating and condensing two amino acid molecules are called dipeptides, and similarly, tripeptides, tetrapeptides, pentapeptides, and the like, and up to nonapeptides, and a desalting apparatus is used for desalting polypeptides.

When the existing desalting device is used, the filtering efficiency is low, which mainly includes that the operation is complex and the solution is slowly permeated during filtering, so that the desalting process is too long, and the desalting efficiency of the polypeptide is reduced, so that a device for desalting the polypeptide needs to be provided.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a device of polypeptide desalination possesses the efficient advantage of desalination to solve the problem that proposes in the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: a device for polypeptide desalination comprises a box body, wherein a first partition plate and a second partition plate are sequentially and fixedly mounted in an inner cavity of the box body from top to bottom, a third partition plate is fixedly mounted at the bottom of the inner cavity of the box body and positioned at the bottom of the second partition plate, a lifting mechanism is arranged at one side of the inner cavity of the box body and positioned at the third partition plate, one end of the lifting mechanism penetrates through the third partition plate and extends to the outside of the third partition plate, a support plate is fixedly mounted at the top of the support plate, a bottle body is placed at the top of the support plate, the top of the bottle body is communicated with a ring body, a vacuum box is fixedly mounted at one side of the top of the second partition plate, a vacuum pump is communicated with one side of the vacuum box, a measuring cylinder is clamped at one side of the top of the first partition plate, a first pipeline is communicated with the bottom of the measuring cylinder, the bottom of the first pipeline penetrates through the first partition plate and extends to the outside of the first partition plate, and is communicated with a filter cylinder, the bottom intercommunication of straining a section of thick bamboo has the second pipeline, the inner chamber intercommunication that the bottom of second pipeline runs through the vacuum box and extends to the vacuum box has the needle tubing, the bottom intercommunication in vacuum box inner chamber has the third pipeline, the bottom of third pipeline runs through vacuum box, second baffle, ring body and bottle in proper order and extends to the top of bottle inner chamber, the bottom of needle tubing extends to the inner chamber of third body, the casing has been cup jointed on the surface of third body, the bottom of casing and the top joint of ring body.

Preferably, the air exhaust end of the vacuum pump is communicated with one side of the vacuum box, and the air exhaust end of the vacuum pump penetrates through the box body and extends to the outside of the box body.

Preferably, the top of the ring body is provided with a groove matched with the shell, and the bottom of the shell extends to the inner cavity of the groove and is attached to the bottom of the inner cavity of the groove.

Preferably, the top of box just is located the top of graduated flask and slides and pegs graft and have the funnel, the bottom of funnel runs through the box and extends to the inner chamber of box.

Preferably, elevating system includes the screw rod, the bottom of screw rod is passed through the bearing and is rotated the installation with the bottom of box inner chamber, the surperficial threaded connection of screw rod has the swivel nut, one side fixed mounting of screw rod has the bracing piece, the one end of bracing piece runs through the third baffle and extends to the outside of third baffle and one side fixed mounting of backup pad.

Preferably, the top of the supporting plate is provided with a limiting groove matched with the bottle body, and the bottle body is clamped with the top of the supporting plate through the limiting groove.

Compared with the prior art, the beneficial effects of the utility model are that:

the utility model injects the solution into the measuring cylinder through the funnel, the solution enters the filter cylinder through the first pipeline, and the solution is filtered through the filter cylinder; the vacuum pump is used for pumping out the gas in the vacuum box and the bottle body and exhausting the gas to the outside of the box body, so that the inside of the vacuum box and the inside of the bottle body are in a negative pressure state, the speed of the solution is increased when the solution passes through the filter cartridge, and the purpose of increasing the permeation speed is achieved.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a front sectional view of the case of the present invention;

FIG. 3 is a front sectional view of the ring body of the present invention;

fig. 4 is a front sectional view of the vacuum box of the present invention.

In the figure: 1. a box body; 2. a first separator; 3. a second separator; 4. a third partition plate; 5. a lifting mechanism; 51. a screw; 52. a threaded sleeve; 53. a support bar; 6. a support plate; 7. a bottle body; 8. a ring body; 9. a vacuum box; 10. a vacuum pump; 11. a measuring cylinder; 12. a first conduit; 13. a filter cartridge; 14. a second conduit; 15. A third pipeline; 16. a housing; 17. a funnel; 18. a needle cannula.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-4, the present invention provides a technical solution: a polypeptide desalting device comprises a box body 1, wherein a first partition plate 2 and a second partition plate 3 are fixedly installed in the inner cavity of the box body 1 from top to bottom in sequence, a third partition plate 4 is fixedly installed at the bottom of the inner cavity of the box body 1 and positioned at the bottom of the second partition plate 3, a lifting mechanism 5 is arranged at one side of the inner cavity of the box body 1 and positioned at the third partition plate 4, one end of the lifting mechanism 5 penetrates through the third partition plate 4 and extends to the outside of the third partition plate 4, a support plate 6 is fixedly installed at the outer side of the third partition plate 4, a bottle body 7 is placed at the top of the support plate 6, the top of the bottle body 7 is communicated with a ring body 8, a vacuum box 9 is fixedly installed at one side of the top of the second partition plate 3, one side of the vacuum box 9 is communicated with a vacuum pump 10, a measuring cylinder 11 is clamped at one side of the top of the first partition plate 2, the bottom of the measuring cylinder 11 is communicated with a first pipeline 12, the bottom of the first pipeline 12 penetrates through the first partition plate 2 and extends to the outside of the first partition plate 2 and is communicated with a filter cylinder 13, the bottom of the filter cartridge 13 is communicated with a second pipeline 14, the bottom of the second pipeline 14 penetrates through the vacuum box 9 and extends to the inner cavity of the vacuum box 9 to be communicated with a needle tube 18, the bottom of the inner cavity of the vacuum box 9 is communicated with a third pipeline 15, the bottom of the third pipeline 15 sequentially penetrates through the vacuum box 9, the second partition plate 3, the ring body 8 and the bottle body 7 and extends to the upper portion of the inner cavity of the bottle body 7, the bottom of the needle tube 18 extends to the inner cavity of the third pipeline 15, a shell 16 is sleeved on the surface of the third pipeline 15, and the bottom of the shell 16 is clamped with the top of the ring body 8.

The air exhaust end of the vacuum pump 10 is communicated with one side of the vacuum box 9, the air exhaust end of the vacuum pump 10 penetrates through the box body 1 and extends to the outside of the box body 1, and the vacuum pump 10 is arranged and used for exhausting air in the vacuum box 9 and the bottle body 7 out of the box body 1 and enabling the inside of the vacuum box 9 and the inside of the bottle body 7 to be in a negative pressure state.

The recess with 16 looks adaptations of casing is seted up at the top of ring 8, and the bottom of casing 16 extends to the inner chamber of recess and the bottom laminating of recess inner chamber, through setting up the recess, pours into appropriate amount of water into in the recess, and the bottom of casing 16 is submerged to the water in the recess, forms the water seal between casing 16 and ring 8, prevents that the outside air from getting into.

The top of box 1 just is located the top of graduated flask 11 and slides and pegs graft and have funnel 17, and the bottom of funnel 17 runs through box 1 and extends to the inner chamber of box 1, through setting up funnel 17 for the person of facilitating the use pours into solution into graduated flask 11 in.

Elevating system 5 includes screw rod 51, and the installation is rotated through the bottom of bearing and box 1 inner chamber in screw rod 51's bottom, and screw rod 51's surperficial threaded connection has swivel nut 52, and one side fixed mounting of screw rod 51 has bracing piece 53, and the one end of bracing piece 53 runs through third baffle 4 and extends to the outside of third baffle 4 and one side fixed mounting of backup pad 6, through setting up elevating system 5 for conveniently reciprocate bottle 7.

The spacing groove with 7 looks adaptations of bottle is seted up at the top of backup pad 6, and bottle 7 passes through the top joint of spacing groove and backup pad 6, through setting up the spacing groove for carry on spacingly to bottle 7, prevent that bottle 7 from taking place the skew, lead to casing 16 and the unable agreeing with of ring body 8.

Wherein, a through groove which facilitates the movement of the support rod 53 is arranged inside the third clapboard 4; the top of the surface of the screw 51 is sleeved with a bearing seat, and two sides of the bearing seat are respectively fixedly installed with the surface of the third partition plate 4 and the inner wall of the box body 1 and used for reinforcing the screw 51; a water outlet is formed in one side of the shell 16 and is communicated with the bottom of the groove, a rubber plug is inserted into an inner cavity of the water outlet in a sliding mode and is used for conveniently discharging water in the groove through the water outlet, and the rubber plug is used for plugging the water outlet; the filter cartridge 13 is filled with a desalination filter membrane for desalination and filtration of the polypeptide solution.

The working principle is as follows: the solution is injected into the measuring cylinder 11 through the funnel 17, enters the filter cylinder 13 through the first pipeline 12, and is filtered through the filter cylinder 13;

a user injects a proper amount of water into the groove, the screw rod 51 is rotated, the screw rod 51 drives the screw sleeve 52 to move, the screw sleeve 52 drives the supporting plate 6 to move through the supporting rod 53, the supporting plate 6 drives the bottle body 7 to ascend, the bottle body 7 drives the ring body 8 to ascend, the shell 16 is embedded into the groove, the water in the groove submerges the bottom of the shell 16, a water seal is formed between the shell 16 and the ring body 8, and outside air is prevented from entering;

the vacuum pump 10 is started through an external controller, the vacuum pump 10 pumps out the gas in the vacuum box 9 and the bottle body 7 and exhausts the gas to the outside of the box body 1, so that the inside of the vacuum box 9 and the inside of the bottle body 7 are in a negative pressure state, the speed of the solution is increased when the solution passes through the filter cartridge 13, and the purpose of increasing the permeation speed is achieved;

the filtered solution enters the needle tube 18 through the second pipeline 14, then enters the third pipeline 15 through the needle tube 18, and enters the bottle body 7 through the third pipeline 15, and the desalted solution is collected.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A polypeptide desalination device comprises a box body (1), and is characterized in that: the vacuum bottle comprises a box body (1), wherein a first partition plate (2) and a second partition plate (3) are sequentially and fixedly mounted in an inner cavity of the box body (1) from top to bottom, a third partition plate (4) is fixedly mounted at the bottom of the inner cavity of the box body (1) and located at the bottom of the second partition plate (3), an elevating mechanism (5) is arranged at one side of the inner cavity of the box body (1) and located at the third partition plate (4), a supporting plate (6) is fixedly mounted at the outer part of the supporting plate (6) in a penetrating mode at one end of the elevating mechanism (5) and extends to the third partition plate (4), a bottle body (7) is placed at the top of the supporting plate (6), a ring body (8) is communicated with the top of the bottle body (7), a vacuum box (9) is fixedly mounted at one side of the top of the second partition plate (3), a vacuum pump (10) is communicated with one side of the vacuum box (9), a measuring cylinder (11) is clamped at one side of the top of the first partition plate (2), the bottom of the measuring cylinder (11) is communicated with a first pipeline (12), the bottom of the first pipeline (12) penetrates through the first partition plate (2) and extends to the outside of the first partition plate (2) to be communicated with a filter cylinder (13), the bottom of the filter cylinder (13) is communicated with a second pipeline (14), the bottom of the second pipeline (14) penetrates through the vacuum box (9) and extends to the inner cavity of the vacuum box (9) to be communicated with a needle tube (18), the bottom of the inner cavity of the vacuum box (9) is communicated with a third pipeline (15), the bottom of the third pipeline (15) sequentially penetrates through the vacuum box (9), the second partition plate (3), the ring body (8) and the bottle body (7) and extends to the upper part of the inner cavity of the bottle body (7), the bottom of needle tubing (18) extends to the inner chamber of third pipeline (15), casing (16) has been cup jointed on the surface of third pipeline (15), the top joint of the bottom of casing (16) and ring body (8).

2. The apparatus for desalting a polypeptide according to claim 1, wherein: the exhaust end of the vacuum pump (10) is communicated with one side of the vacuum box (9), and the exhaust end of the vacuum pump (10) penetrates through the box body (1) and extends to the outside of the box body (1).

3. The apparatus for desalting a polypeptide according to claim 1, wherein: the top of ring body (8) is seted up with the recess of casing (16) looks adaptation, the bottom of casing (16) extends to the inner chamber of recess and the bottom laminating of recess inner chamber.

4. The apparatus for desalting a polypeptide according to claim 1, wherein: the top of box (1) just is located the top of graduated flask (11) and slides and pegs graft and have funnel (17), the bottom of funnel (17) runs through box (1) and extends to the inner chamber of box (1).

5. The apparatus for desalting a polypeptide according to claim 1, wherein: elevating system (5) include screw rod (51), the bottom of screw rod (51) is passed through the bearing and is rotated the installation with the bottom of box (1) inner chamber, the surperficial threaded connection of screw rod (51) has swivel nut (52), one side fixed mounting of screw rod (51) has bracing piece (53), the one end of bracing piece (53) runs through third baffle (4) and extends to one side fixed mounting of the outside of third baffle (4) and backup pad (6).

6. The apparatus for desalting a polypeptide according to claim 1, wherein: the top of backup pad (6) is seted up the spacing groove with bottle (7) looks adaptation, bottle (7) are through the top joint of spacing groove and backup pad (6).