CN214585462U - Immunohistochemical antibody smearing device - Google Patents
Immunohistochemical antibody smearing device Download PDFInfo
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- CN214585462U CN214585462U CN202120622383.1U CN202120622383U CN214585462U CN 214585462 U CN214585462 U CN 214585462U CN 202120622383 U CN202120622383 U CN 202120622383U CN 214585462 U CN214585462 U CN 214585462U
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- locking screw
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- fixedly connected
- antibody
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Abstract
The utility model discloses an immunohistochemical antibody uniform smearing device, which comprises a base, a mounting hole, a stepped shaft, a first locking screw, a movable seat, a handle, a second locking screw, a movable arm, a rack, a guide groove, a gear, a first knob, a guide sleeve, an end cover, a second knob, a screw, a lifting arm, a motor, a magnetic sucker, a smearing head, a side baffle and a clamping groove; in the utility model, the locking screw is loosened to facilitate the manual rotation of the whole movable seat, and the locking screw is loosened to facilitate the manual drawing of the movable arm, so that the smearing head can be manually and rapidly adjusted above the antibody, and the convenience of operation is improved; the first knob arranged in the utility model can precisely adjust the extending distance of the movable arm through the gear and the rack, thereby further improving the convenience and the accuracy of operation and use; the utility model discloses well locking screw one and locking screw two to horizontal migration appears when having avoided smearing the head and having paintd, can not surpass the slide glass when having ensured to paint the antibody.
Description
Technical Field
The utility model relates to an experimental device technical field, specific even ware is smeared to immunohistochemical antibody that says so.
Background
In the laboratory carrying out immunohistochemical experimentation, need place the tissue on the slide usually, then drop wise antibody on the tissue, the antibody of dropwise add is because the effect of water molecule tension, and the antibody can not even distribution on the tissue, usually for solving this problem, the operator can use the rifle head of dropwise add the antibody to paint antibody and tissue evenly, but this process has following problem: firstly, the gun head is made of hard material, so that the tissue is easily damaged in the smearing process, the tissue is scratched, and the experimental result is influenced; secondly, in the smearing process, as the broken piece is small in size and the operation precision cannot be controlled, the gun head is easy to scratch out of the glass slide during operation, and under the tension action of water molecules of the antibody, the antibody is led to take the tissue out of the glass slide along with the gun head, so that the tissue and the antibody flow outwards, experiments cannot be carried out, new immunohistochemistry objects need to be manufactured again, the existing immunohistochemical antibody smearing device is troublesome and inconvenient to operate, and the non-smearing part of the smearing device is easy to contact with the immunohistochemical objects to cause pollution.
SUMMERY OF THE UTILITY MODEL
To the above-mentioned not enough that exists among the prior art, the utility model aims at providing an even ware is smeared to immunohistochemical antibody has solved the even ware operation of current immunohistochemical antibody and has more troublesome and inconvenient, and smears even ware non-smearing part and causes the problem of pollution with immunohistochemical thing contact easily.
The utility model discloses a realize that the technical scheme that above-mentioned purpose adopted is: an immunohistochemical antibody uniform smearing device is innovatively characterized by comprising a base, a mounting hole, a stepped shaft, a first locking screw, a movable seat, a handle, a second locking screw, a movable arm, a rack, a guide groove, a gear, a first knob, a guide sleeve, an end cover, a second knob, a screw, a lifting arm, a motor, a magnetic sucker, a smearing head, a side baffle and a clamping groove; a mounting hole is formed in the left side of the base, a transverse clamping groove is formed in the right upper side of the base, and side baffles are fixedly connected to the front and rear positions of the clamping groove; the stepped shaft is movably connected to the upper side of the mounting hole, and the top of the stepped shaft is fixedly connected with the center of the bottom of the movable seat; the first locking screw is movably connected in a threaded hole formed in the left upper side of the mounting hole, and the end of the inner side of the first locking screw is connected with the outer surface of the stepped shaft; the left lower side of the movable seat is fixedly connected with a handle, and a transverse guide groove is formed in the upper side of the movable seat; the movable arm is transversely movably connected inside the guide groove, and a transverse rack is fixedly connected to the side surface of the upper side of the movable arm; the locking screw II is movably connected in an inclined threaded hole formed in the left lower side of the guide groove, and the upper side of the locking screw II is connected with the bottom surface of the movable arm; the gear is movably connected to the center of the upper surface of the front side of the guide groove, a tooth part at the rear side of the gear is connected with the rack, and a first knob is fixedly connected to the upper side of the central shaft of the gear; the outer part of the left lower side of the guide sleeve is fixedly connected to the right side end part of the movable arm, and an opening at the upper side of the guide sleeve is fixedly connected with an end cover; the screw is movably connected to the center inside the guide sleeve, the outer part of the upper side of the screw is movably connected to the inner part of the center of the end cover, and the end part of the upper side of the screw is fixedly connected with a second knob; the lifting arm is vertically and movably connected inside the guide sleeve, and a threaded hole formed in the center of the lifting arm is connected with the screw rod; the motor is fixedly connected inside the lower side of the lifting arm, and an output shaft at the lower side of the motor is fixedly connected with the center of the upper side of the magnetic sucker; and an iron sheet arranged on the upper side of the smearing head is connected with the lower side of the magnetic sucker.
Preferably, the first locking screw and the second locking screw are provided with anti-skid grains on the outer side surfaces.
Preferably, the motor is a reduction motor.
Preferably, a plurality of bristles are arranged on the bottom surface of the smearing head.
Preferably, the side barrier is a transparent plate.
The utility model has the advantages that:
(1) the utility model discloses in here loosen locking screw one and be convenient for the manual rotation sliding seat whole, and loosen locking screw two then be convenient for manual pull digging arm to can adjust the antibody top through manual quick will scribbling the head, improve the convenience of operation.
(2) The utility model discloses in the knob that sets up one, then can be through the distance that the accurate regulation digging arm of gear and rack stretches out, further improved convenience and the accuracy of operation and use.
(3) The utility model discloses well locking screw one and locking screw two to horizontal migration appears when having avoided smearing the head and having paintd, just also ensured not surpassing the slide glass when smearing the antibody.
(4) The utility model discloses in hold the head of smearing through magnetic chuck to be convenient for smear the quick replacement of head, ensured the accuracy and the reliability of experiment.
(5) The utility model discloses well two drive screw rod rotations of manual rotatory knob order about the lifing arm wholly move down evenly to paint the antibody through rotatory head of smearing, have also avoided the contact above other positions of this even ware of smearing and the slide glass to cause the pollution simultaneously.
Drawings
Fig. 1 is a schematic structural view of the present invention;
fig. 2 is a partial enlarged view of the present invention.
In the figure: 1-a base; 2-mounting holes; 3-a stepped shaft; 4, locking the first screw; 5-a movable seat; 6-a handle; 7-locking a second screw; 8-a movable arm; 9-a rack; 10-a guide groove; 11-a gear; 12-knob one; 13-guide sleeve; 14-an end cap; 15-knob two; 16-a screw; 17-a lifting arm; 18-a motor; 19-a magnetic chuck; 20-smearing head; 21-side baffle; 22-card slot.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
As shown in fig. 1-2, an immunohistochemical antibody homogenizer comprises a base 1, a mounting hole 2, a stepped shaft 3, a first locking screw 4, a movable seat 5, a handle 6, a second locking screw 7, a movable arm 8, a rack 9, a guide groove 10, a gear 11, a first knob 12, a guide sleeve 13, an end cover 14, a second knob 15, a screw 16, a lifting arm 17, a motor 18, a magnetic chuck 19, a smearing head 20, a side baffle 21 and a clamping groove 22; a mounting hole 2 is formed in the left side of the base 1, a transverse clamping groove 22 is formed in the right upper side of the base 1, and side baffles 21 are fixedly connected to the front and rear positions of the clamping groove 22; the stepped shaft 3 is movably connected to the upper side of the mounting hole 2, and the top of the stepped shaft 3 is fixedly connected with the center of the bottom of the movable seat 5; the locking screw I4 is movably connected in a threaded hole formed in the left upper side of the mounting hole 2, and the end of the inner side of the locking screw I4 is connected with the outer surface of the stepped shaft 3; a handle 6 is fixedly connected to the left lower side of the movable seat 5, and a transverse guide groove 10 is formed in the upper side of the movable seat 5; the movable arm 8 is transversely movably connected inside the guide groove 10, and the lateral side of the upper side of the movable arm 8 is fixedly connected with a transverse rack 9; the locking screw II 7 is movably connected in an inclined threaded hole formed in the left lower side of the guide groove 10, and the upper side of the locking screw II 7 is connected with the bottom surface of the movable arm 8; the gear 11 is movably connected to the center of the upper surface of the front side of the guide groove 10, the gear part of the rear side of the gear 11 is connected with the rack 9, and the upper side of the central shaft of the gear 11 is fixedly connected with a knob I12; the outer part of the left lower side of the guide sleeve 13 is fixedly connected with the right side end part of the movable arm 8, and an opening at the upper side of the guide sleeve 13 is fixedly connected with an end cover 14; the screw 16 is movably connected to the center inside the guide sleeve 13, the outer part of the upper side of the screw 16 is movably connected to the inner part of the center of the end cover 14, and the end part of the upper side of the screw 16 is fixedly connected with a second knob 15; the lifting arm 17 is vertically movably connected inside the guide sleeve 13, and a threaded hole formed in the center of the lifting arm 17 is connected with the screw 16; the motor 18 is fixedly connected inside the lower side of the lifting arm 17, and an output shaft at the lower side of the motor 18 is fixedly connected with the center of the upper side of the magnetic sucker 19; the iron sheet arranged on the upper side of the smearing head 20 is connected with the lower side of the magnetic sucker 19.
The outer side surfaces of the first locking screw 4 and the second locking screw 7 are provided with anti-skid grains; the motor 18 is a speed reducing motor; the bottom surface of the smearing head 20 is provided with a plurality of bristles; the side barrier 21 is a transparent plate.
The utility model has the using state that when in use, firstly, the tissue is placed on the glass slide, then the antibody is dripped on the tissue, then the glass slide is inserted into the clamping groove 22, then the smearing head 20 is adjusted above the antibody, when in specific adjustment, firstly, the locking screw I4 and the locking screw II 7 are loosened, the locking screw I4 is loosened to facilitate the manual rotation of the movable seat 5 as a whole, the locking screw II 7 is loosened to facilitate the manual drawing of the movable arm 8, thereby the smearing head 20 can be adjusted above the antibody through manual and rapid adjustment, the convenience of operation is also improved, the set knob I12 can accurately adjust the distance extending out of the movable arm 8 through the gear 11 and the rack 9, thereby the convenience and the accuracy of operation and use are further improved, then, the locking screw I4 and the locking screw II 7 are locked, thereby the horizontal movement when the smearing head 20 is smeared is avoided, just also ensured not surpassing the slide glass when paining the antibody, then the starter motor 18 drives through magnetic chuck 19 and scribbles the head 20 rotatory, here hold smearing head 20 through magnetic chuck 19, thereby be convenient for scribble the quick replacement of head 20, the accuracy and the reliability of experiment have also been ensured, at last manual rotatory knob two 15 drive the screw rod 16 rotation and drive the lift arm 17 wholly move down evenly to scribble the head 20 and evenly paint the antibody through rotatory, just also avoided other positions of this even ware and slide glass above the contact cause the pollution simultaneously.
The control mode of the present invention is controlled by manual starting or by the existing automation technology, the connection diagram of the power element and the supply of the power source belong to the common knowledge in the field, and the present invention is mainly used for protecting the mechanical device, so the present invention does not explain the control mode and the wiring arrangement in detail.
In the description of the present invention, it is to be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "one side", "top", "inner", "front", "center", "both ends", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations.
The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above, and it should be understood by those skilled in the art that the present invention is not limited by the above embodiments, which are only illustrative, but also various changes and modifications may be made without departing from the spirit and scope of the present invention, which fall within the scope of the present invention as claimed, which is defined by the appended claims and their equivalents.
Claims (5)
1. An immunohistochemical antibody uniform smearing device is characterized by comprising a base (1), a mounting hole (2), a stepped shaft (3), a locking screw I (4), a movable seat (5), a handle (6), a locking screw II (7), a movable arm (8), a rack (9), a guide groove (10), a gear (11), a knob I (12), a guide sleeve (13), an end cover (14), a knob II (15), a screw rod (16), a lifting arm (17), a motor (18), a magnetic sucker (19), a smearing head (20), a side baffle (21) and a clamping groove (22);
a mounting hole (2) is formed in the left side of the base (1), a transverse clamping groove (22) is formed in the right upper side of the base (1), and side baffles (21) are fixedly connected to the front and rear positions of the clamping groove (22);
the stepped shaft (3) is movably connected to the upper side of the mounting hole (2), and the top of the stepped shaft (3) is fixedly connected with the center of the bottom of the movable seat (5);
the locking screw I (4) is movably connected in a threaded hole formed in the left upper side of the mounting hole (2), and the end of the inner side of the locking screw I (4) is connected with the outer surface of the stepped shaft (3);
a handle (6) is fixedly connected to the lower left side of the movable seat (5), and a transverse guide groove (10) is formed in the inner side of the upper side of the movable seat (5);
the movable arm (8) is transversely movably connected inside the guide groove (10), and the lateral side of the upper side of the movable arm (8) is fixedly connected with a transverse rack (9);
the locking screw II (7) is movably connected in an inclined threaded hole formed in the left lower side of the guide groove (10), and the upper side of the locking screw II (7) is connected with the bottom surface of the movable arm (8);
the gear (11) is movably connected to the center of the upper surface of the front side of the guide groove (10), the tooth part of the rear side of the gear (11) is connected with the rack (9), and the upper side of the central shaft of the gear (11) is fixedly connected with a first knob (12);
the outer part of the lower left side of the guide sleeve (13) is fixedly connected with the right side end part of the movable arm (8), and an opening on the upper side of the guide sleeve (13) is fixedly connected with an end cover (14);
the screw rod (16) is movably connected to the center inside the guide sleeve (13), the outer part of the upper side of the screw rod (16) is movably connected to the inner part of the center of the end cover (14), and the end part of the upper side of the screw rod (16) is fixedly connected with a second knob (15);
the lifting arm (17) is vertically movably connected inside the guide sleeve (13), and a threaded hole formed in the center of the lifting arm (17) is connected with the screw rod (16);
the motor (18) is fixedly connected to the inner part of the lower side of the lifting arm (17), and an output shaft of the lower side of the motor (18) is fixedly connected with the center of the upper side of the magnetic sucker (19);
the iron sheet arranged on the upper side of the smearing head (20) is connected with the lower side of the magnetic sucker (19).
2. The immunohistochemical antibody homogenizer of claim 1, wherein the outer side surfaces of the first locking screw (4) and the second locking screw (7) are provided with anti-skid lines.
3. An immunohistochemical antibody homogenizer according to claim 1, wherein said motor (18) is a speed reducing motor.
4. An immunohistochemical antibody homogenizer according to claim 1, wherein said bottom surface of said smearing head (20) is provided with a plurality of bristles.
5. An immunohistochemical antibody homogenizer according to claim 1, wherein said side baffles (21) are transparent plates.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202120622383.1U CN214585462U (en) | 2021-03-28 | 2021-03-28 | Immunohistochemical antibody smearing device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202120622383.1U CN214585462U (en) | 2021-03-28 | 2021-03-28 | Immunohistochemical antibody smearing device |
Publications (1)
Publication Number | Publication Date |
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CN214585462U true CN214585462U (en) | 2021-11-02 |
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ID=78355855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN202120622383.1U Expired - Fee Related CN214585462U (en) | 2021-03-28 | 2021-03-28 | Immunohistochemical antibody smearing device |
Country Status (1)
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CN (1) | CN214585462U (en) |
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2021
- 2021-03-28 CN CN202120622383.1U patent/CN214585462U/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211102 |
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CF01 | Termination of patent right due to non-payment of annual fee |