CN214572046U - Batch spinner flask cell culture device - Google Patents
Batch spinner flask cell culture device Download PDFInfo
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- CN214572046U CN214572046U CN202023286644.1U CN202023286644U CN214572046U CN 214572046 U CN214572046 U CN 214572046U CN 202023286644 U CN202023286644 U CN 202023286644U CN 214572046 U CN214572046 U CN 214572046U
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- cell culture
- culture device
- rotating
- rotary rod
- rod
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Abstract
The utility model discloses a batch bottle-rotating cell culture device, which comprises a frame and a plurality of rotary rods, wherein a vertical plate is fixed on the frame, one end of each rotary rod is respectively provided with a supporting shaft, the supporting shafts at one end of each rotary rod are respectively connected on the vertical plate in a rotating way at intervals, and each rotary rod is driven by a motor to rotate synchronously; the rotating rods are respectively sleeved with a cell culture device which synchronously rotates with the rotating rods. In the utility model, the cell culture device is positioned on the rotating rod by adopting a plug-in mode, the upper frame and the lower frame are simple and quick, the storage is convenient, and the cells are easy to carry during observation; each rotating rod is correspondingly provided with a cell culture device to realize the ordered storage of the cell culture devices; in addition, when not in use, each rotating rod can be detached, and the occupied space is reduced.
Description
Technical Field
The utility model belongs to the cell culture device field, in particular to batch spinner flask cell culture device.
Background
In the vaccine production process, the spinner bottle cells are cultured on a spinner bottle machine, the glass bottle is large, the culture solution is filled in the glass bottle is heavy, the space of each bottle position of the spinner bottle is compact, and the cell growth condition needs to be observed in the spinner bottle cell culture process. The existing bottle rotating machine mainly has the following defects:
1. the problem of difficulty in loading and unloading is solved, the action amplitude is too large in the carrying process, cells are flaked and shed, and the cells in the whole bottle cannot be passaged and are discarded;
2. each bottle position of the bottle rotating machine is compact in space and difficult to store;
3. the traditional bottle rotating machine occupies space;
4. the rotary bottle is made of glass and is easy to break.
Disclosure of Invention
In order to solve the deficiencies in the prior art, the utility model provides a batch spinner flask cell culture device to guarantee that the cell pastes the wall and evenly grows in the spinner flask, improve product quality.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a batch spinner flask cell culture device comprises a rack and a plurality of rotary rods, wherein a vertical plate is fixed on the rack, one end of each rotary rod is respectively provided with a support shaft, the support shafts at one end of each rotary rod are respectively connected to the vertical plate in a rotating manner at intervals, and each rotary rod is driven by a motor to rotate synchronously; the rotating rods are respectively sleeved with a cell culture device which synchronously rotates with the rotating rods.
Furthermore, the cross section of the rotating rod is polygonal, a middle shaft hole matched with the shape of the cross section of the rotating rod is arranged at the middle shaft position of the cell culture device, and the middle shaft hole is sleeved on the rotating rod and synchronously rotates along with the rotating rod.
Further, one of the ends of the rotary rod close to the supporting shaft is provided with an axial fixed baffle, one of the ends of the rotary rod far away from the supporting shaft is provided with a connecting shaft, the connecting shaft is movably sleeved with an axial movable baffle, the upper connecting thread is connected with a locking handle, and the cell culture device sleeved on the rotary rod is limited between the axial fixed baffle and the axial movable baffle by the locking handle.
Further, the cell culture device is molded from a resin material.
Furthermore, the outer wall of the cell culture device is connected with an exhaust pipe, a feed inlet and a discharge outlet, and a sealing cover is detachably connected to the feed inlet and the discharge outlet.
Furthermore, the output shaft of the motor is in transmission connection with the supporting shaft of one of the rotating rods through a synchronous belt transmission mechanism, and the supporting shafts at one ends of the other rotating rods and the supporting shafts of the adjacent rotating rods are also in transmission connection through the synchronous belt transmission mechanism.
The utility model adopts the above technical scheme, following beneficial effect has:
1. the cell culture device is positioned on the rotating rod in an inserting mode, the upper frame and the lower frame are simple and quick, the storage is convenient, and cells are easy to carry during observation;
2. each rotating rod is correspondingly provided with a cell culture device to realize the ordered storage of the cell culture devices;
3. when not in use, each rotating rod can be disassembled, so that the occupied space is reduced;
4. the cell culture device is molded by resin and is not easy to break.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments;
fig. 1 is a front view of the present invention;
fig. 2 is a side view of the present invention;
FIG. 3 is a schematic view of the structure of the cell culture apparatus.
Detailed Description
As shown in fig. 1-3, the present invention relates to a batch spinner flask cell culture apparatus, which comprises a frame 1 and a plurality of rotating rods 2, wherein a vertical plate 11 is fixed on the frame 1, one end of each rotating rod 2 is provided with a supporting shaft 21, the supporting shafts 21 at one end of each rotating rod 2 are respectively connected to the vertical plate 11 in a rotating manner at intervals (via bearings), and each rotating rod 2 is driven by a motor 3 to rotate synchronously; the rotating rods 2 are respectively sleeved with a cell culture device 4 which rotates synchronously with the rotating rods.
The cross section of rotary rod 2 is the polygon, be equipped with on the axis position of cell culture ware 4 with the middle shaft hole 41 of 2 section shape looks adaptations of rotary rod, this middle shaft hole 41 cup joints on rotary rod 2 and rotates along with rotary rod 2 is synchronous, adopts above-mentioned design, can realize cell culture ware 4 and rotary rod 2 synchronous rotation under the condition that does not increase other connecting pieces, simple structure, it is with low costs.
One of rotary rod 2 near back shaft 21 serves and is equipped with axial fixed baffle 5, one of back shaft 21 is kept away from to rotary rod 2 serves and is equipped with connecting axle 22, and the activity has cup jointed axial adjustable fender 6 on the connecting axle 22, connect upward threaded connection and have locking handle 7, thereby the locking handle 7 of screwing will cup joint cell culture ware 4 on rotary rod 2 and spacing between axial fixed baffle 5 and axial adjustable fender 6. Above-mentioned structure can be stably, effectively be fixed in cell culture ware 4 on rotary rod 2, and the process of dismouting cell culture ware 4 is simple moreover, easy operation.
The cell culture device 4 is molded by resin material and is not easy to break. The outer wall of the cell culture device 4 is connected with an exhaust pipe 42 and a feed and discharge port 43, and the feed and discharge port 43 is detachably connected with a sealing cover 44.
The output shaft of the motor 3 is in transmission connection with the support shaft 21 of one of the rotating rods 2 through a synchronous belt transmission mechanism 8, and the support shafts 21 at one ends of the other rotating rods 2 are in transmission connection with the support shafts 21 of the adjacent rotating rods 2 through a synchronous belt transmission mechanism 9.
The utility model discloses a use method:
1. materials such as nutrient solution, cells and the like are filled into the cell culture device 4 through the material inlet and outlet 43 and then sealed;
2. unscrewing a locking handle 7, taking down an axial movable baffle 6, installing a cell culture device 4 provided with cell sap on a rotating rod 2, installing the axial movable baffle 6, and screwing the locking handle 7;
3. the power supply of the control cabinet is started, the rotating speed of the motor 3 is set, and the rotating rods 2 are driven by the motor 3 to synchronously rotate so as to achieve the effect of continuous rotation of the cell culture device 4.
The practice of the present invention has been described with reference to the accompanying drawings, but the invention is not limited to the embodiments described above, which are illustrative rather than limiting, and it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the scope of the embodiments of the present invention, and are intended to be covered by the claims and the specification.
Claims (5)
1. The utility model provides a batch spinner bottle cell culture device which characterized in that: the vertical plate is fixed on the rack, one end of each rotary rod is provided with a support shaft, the support shafts at one end of each rotary rod are respectively connected to the vertical plate in a rotating mode at intervals, and each rotary rod is driven by a motor to rotate synchronously; the output shaft of the motor is in transmission connection with the support shaft of one of the rotating rods through a synchronous belt transmission mechanism, and the support shafts at one end of the other rotating rods are in transmission connection with the support shafts of the adjacent rotating rods through the synchronous belt transmission mechanism.
2. A batch spinner flask cell culture apparatus according to claim 1, wherein: the cross section of the rotating rod is polygonal, a middle shaft hole matched with the shape of the cross section of the rotating rod is arranged at the middle shaft position of the cell culture device, and the middle shaft hole is sleeved on the rotating rod and synchronously rotates along with the rotating rod.
3. A batch roller bottle cell culture apparatus according to claim 1 or 2, wherein: the cell culture device is characterized in that one end, close to the supporting shaft, of the rotary rod is provided with an axial fixed baffle, one end, far away from the supporting shaft, of the rotary rod is provided with a connecting shaft, an axial movable baffle is movably sleeved on the connecting shaft, the upper threaded connection of the connecting shaft is provided with a locking handle, and the cell culture device sleeved on the rotary rod is limited between the axial fixed baffle and the axial movable baffle by the aid of the locking handle.
4. A batch spinner flask cell culture apparatus according to claim 1, wherein: the cell culture device is molded from a resin material.
5. A batch spinner flask cell culture apparatus according to claim 1, wherein: the outer wall of the cell culture device is connected with an exhaust pipe, a feed inlet and a discharge outlet, and a sealing cover is detachably connected to the feed inlet and the discharge outlet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023286644.1U CN214572046U (en) | 2020-12-30 | 2020-12-30 | Batch spinner flask cell culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023286644.1U CN214572046U (en) | 2020-12-30 | 2020-12-30 | Batch spinner flask cell culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214572046U true CN214572046U (en) | 2021-11-02 |
Family
ID=78335755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023286644.1U Active CN214572046U (en) | 2020-12-30 | 2020-12-30 | Batch spinner flask cell culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214572046U (en) |
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2020
- 2020-12-30 CN CN202023286644.1U patent/CN214572046U/en active Active
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