CN214552870U - A pH value adjusting device for tropisetron hydrochloride - Google Patents

A pH value adjusting device for tropisetron hydrochloride Download PDF

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Publication number
CN214552870U
CN214552870U CN202120539487.6U CN202120539487U CN214552870U CN 214552870 U CN214552870 U CN 214552870U CN 202120539487 U CN202120539487 U CN 202120539487U CN 214552870 U CN214552870 U CN 214552870U
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Prior art keywords
pipe
regulating box
fixedly connected
adjusting device
box
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CN202120539487.6U
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Chinese (zh)
Inventor
王瑛
杨慧卿
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Jinan Kangqiao Pharmaceutical R&d Co ltd
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Jinan Kangqiao Pharmaceutical R&d Co ltd
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Abstract

The utility model discloses a pH value adjusting device for tropisetron hydrochloride, including the regulating box, the regulating box bottom is equipped with the supporting legs, regulating box lower surface middle part is equipped with the PLC controller, regulating box inside wall one side fixedly connected with PH sensor, the discharge gate has been seted up to one side that the PH sensor was kept away from to the regulating box lateral wall, regulating box roof fixedly connected with bearing, the sealed fixedly connected with rotating tube of bearing inner circle. The utility model discloses a set up air pump, rotating tube, stirring leaf, stirred tube and venthole, can inflate to the stirred tube inside through the air pump and drive stirring leaf and stirred tube rotation, cooperate the venthole simultaneously, can let hydrochloric acid tropisetron mix more rapidly with the aqueous ammonia, shorten hydrochloric acid tropisetron PH value's adjust time, improve output efficiency, drive the piston motion through electronic push-and-pull rod in addition and add the aqueous ammonia, can be so that hydrochloric acid tropisetron PH value adjusts more accurately.

Description

A pH value adjusting device for tropisetron hydrochloride
Technical Field
The utility model relates to a pharmaceutical production technical field especially relates to a pH value adjusting device for tropisetron hydrochloride.
Background
Tropisetron hydrochloride is a highly potent and selective 5-HT3 receptor antagonist that selectively inhibits the activation of presynaptic 5-HT3 receptors in the peripheral nervous system and possibly 5-HT in the central nervous system in this reflex, a highly selective inhibitor of 5-HT3 receptors in peripheral and central nervous systems. Can be used for treating emesis caused by chemotherapy and radiotherapy. In the production process of the tropisetron hydrochloride, the pH value of the tropisetron hydrochloride needs to be adjusted by adding ammonia water.
Among the prior art, through the manual work ammonia water of dropwise add in to the tropisetron hydrochloride, then the PH value of tropisetron hydrochloride is adjusted to the mode of sample measurement again, this kind of mode of adjusting the PH value, efficiency is too low, and certain error can appear in the manual work measurement, lead to the certain problem of production tropisetron hydrochloride quality appearance, also have in addition to adjust the PH value of tropisetron hydrochloride through PH value adjusting device, but current tropisetron hydrochloride PH value adjusting device is when stirring tropisetron hydrochloride, the stirring is insufficient, the churning time is longer, thereby influence the output efficiency of tropisetron hydrochloride.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects existing in the prior art and providing a pH value adjusting device for tropisetron hydrochloride.
In order to achieve the above purpose, the utility model adopts the following technical scheme: a pH value adjusting device for tropisetron hydrochloride comprises an adjusting box, supporting legs are arranged at the bottom end of the adjusting box, a PLC is arranged in the middle of the lower surface of the adjusting box, a pH sensor is fixedly connected to one side of the inner side wall of the adjusting box, a discharge hole is formed in one side, away from the pH sensor, of the side wall of the adjusting box, a bearing is fixedly connected to the top wall of the adjusting box, a rotating pipe is fixedly connected to the inner ring of the bearing in a sealing manner, two stirring pipes are connected to two sides of the bottom end of the rotating pipe, a plurality of stirring blades are fixedly connected to the middle of the outer surface of the rotating pipe, an air pump is arranged on the upper surface of the adjusting box, an air outlet pipe is fixedly connected to the air outlet end of the air outlet pipe, a pipe sleeve is connected to one end, away from the air pump, an adding hole is formed in one side of the top end of the adjusting box, two side plates are fixed to two sides of the outer side wall of the adjusting box, and two liquid storage pipes are fixed to the upper surfaces of the two side plates, the two liquid storage pipes are connected with two pistons in a sliding mode, the two sides of the bottom ends of the two liquid storage pipes are connected with a liquid inlet pipe and a liquid outlet pipe respectively, the two top ends of the two sides of the adjusting box are fixed with two electric push-pull rods, and the telescopic ends of the two electric push-pull rods are fixedly connected with the upper surfaces of the two pistons respectively.
As a further description of the above technical solution:
and a plurality of air outlets are formed in the side walls of the two stirring pipes, and the directions of the air outlets on the two stirring pipes are opposite.
As a further description of the above technical solution:
the top end of the rotating pipe is connected with the pipe sleeve in a sealing and rotating mode.
As a further description of the above technical solution:
the liquid inlet pipe and the liquid outlet pipe are respectively provided with a first electromagnetic valve and a second electromagnetic valve in the middle, and one end of the liquid outlet pipe, which is far away from the liquid storage pipe, penetrates through the side wall of the adjusting box and extends into the adjusting box.
As a further description of the above technical solution:
and the electric push-pull rod and the PH sensor are electrically connected with the PLC.
As a further description of the above technical solution:
the surface of the adjusting box is provided with a visual window.
The utility model discloses following beneficial effect has:
1. the utility model discloses a set up air pump, rotating tube, stirring leaf, stirred tubular and venthole, after adding the aqueous ammonia, when stirring hydrochloric acid tropisetron, can go into the air to the inside pump of stirred tubular through the air pump, then drive stirred tubular and stirring leaf and rotate in the regulating box is inside to roll hydrochloric acid tropisetron through the air current, let aqueous ammonia and hydrochloric acid tropisetron react faster, thereby shorten the adjust time of pH value greatly, improve output efficiency.
2. The utility model discloses a set up PLC controller, PH sensor, electronic push-and-pull rod, liquid storage pipe and piston to according to the feedback of PH sensor, real time control electronic push-and-pull rod is flexible, drives piston motion, adds aqueous ammonia or water from this, adjusts the pH value of hydrochloric acid tropisetron, makes pH value adjust more accurate.
Drawings
Fig. 1 is a main sectional view of a pH adjusting device for tropisetron hydrochloride according to the present invention;
fig. 2 is an enlarged view of a pH adjusting device a for tropisetron hydrochloride according to the present invention;
fig. 3 is a front view of the pH adjusting device for tropisetron hydrochloride according to the present invention.
Illustration of the drawings:
1. an adjusting box; 2. supporting legs; 3. a PLC controller; 4. a pH sensor; 5. a discharge port; 6. a bearing; 7. rotating the tube; 8. a stirring pipe; 9. an air outlet; 10. stirring blades; 11. an air pump; 12. an air outlet pipe; 13. pipe sleeve; 14. an addition port; 15. a side plate; 16. a liquid storage pipe; 17. a piston; 18. a liquid inlet pipe; 19. a liquid outlet pipe; 20. a first solenoid valve; 21. a second solenoid valve; 22. an electric push-pull rod; 23. a visible window.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to fig. 1-3, the present invention provides an embodiment: a pH value adjusting device for tropisetron hydrochloride comprises an adjusting box 1, supporting legs 2 are arranged at the bottom end of the adjusting box 1, a PLC 3 is arranged in the middle of the lower surface of the adjusting box 1, a pH sensor 4 is fixedly connected to one side of the inner side wall of the adjusting box 1, a discharge hole 5 is formed in one side of the side wall of the adjusting box 1, which is far away from the pH sensor 4, a bearing 6 is fixedly connected to the top wall of the adjusting box 1, a rotating pipe 7 is fixedly connected to the inner ring of the bearing 6 in a sealing manner, two stirring pipes 8 are connected to two sides of the bottom end of the rotating pipe 7, a plurality of stirring blades 10 are fixedly connected to the middle of the outer surface of the rotating pipe 7, an air pump 11 is arranged on the upper surface of the adjusting box 1, an air outlet pipe 12 is fixedly connected to the air outlet pipe 11, a pipe sleeve 13 is connected to one end of the air outlet pipe 12, an adding hole 14 is formed in one side of the top end of the adjusting box 1, two side plates 15 are fixed with two side plates 15, two pistons 17 are slidably connected inside the two liquid storage pipes 16, a liquid inlet pipe 18 and a liquid outlet pipe 19 are respectively connected to two sides of the bottom ends of the two liquid storage pipes 16, two electric push-pull rods 22 are fixed to the top ends of two sides of the adjusting box 1, and the telescopic ends of the two electric push-pull rods 22 are respectively fixedly connected with the upper surfaces of the two pistons 17.
A plurality of ventholes 9 have all been seted up to two 8 lateral walls of agitator pipe, and 9 opposite directions of venthole on two agitator pipes 8 are convenient for two agitator pipes 8 and rotate under the air current promotes.
The top end of the rotating tube 7 is connected with the tube sleeve 13 in a sealing and rotating way, so that the rotating tube 7 can rotate while transmitting air flow.
The middle parts of the liquid inlet pipe 18 and the liquid outlet pipe 19 are respectively provided with a first electromagnetic valve 20 and a second electromagnetic valve 21, and one end of the liquid outlet pipe 19, which is far away from the liquid storage pipe 16, penetrates through the side wall of the adjusting box 1 and extends into the adjusting box 1, so that ammonia water or water can be accurately added into the adjusting box 1.
Electric push-pull rod 22 and PH sensor 4 all with PLC controller 3 electric connection, through PH sensor 4 measurement feedback for PLC controller 3 can accurate control electric push-pull rod 22's stroke.
The surface of the adjusting box 1 is provided with a visual window 23, so that the stirring inside the adjusting box 1 can be observed conveniently.
The working principle is as follows: ammonia water and water are respectively stored in the two liquid storage pipes 16, when the device is used, tropisetron hydrochloride is added into the adjusting box 1 through the adding port 14, then the air pump 11 is started, air is discharged from the air outlet hole 9 of the stirring pipe 8 through the air outlet pipe 12 and the rotating pipe 7, therefore, under the push of the air flow, the stirring pipe 8 starts to rotate and drives the stirring blade 10 to rotate, at the moment, the pH sensor 4 can monitor the pH value of the tropisetron hydrochloride in real time and feed back information to the PLC controller 3, then the first electromagnetic valve 20 is closed, the second electromagnetic valve 21 is opened, the PLC controller 3 can selectively control one of the electric push-pull rods 22 to press down to drive the piston 17 to press down, ammonia water or water is added into the adjusting box 1 to adjust the pH value of the tropisetron hydrochloride, when the first electromagnetic valve 20 is opened and the second electromagnetic valve 21 is closed, the PLC controller 3 controls the electric push-pull rod 22 to ascend so as to add ammonia water or water into the liquid storage pipe 16.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims (6)

1. The utility model provides a pH value adjusting device for tropisetron hydrochloride, includes regulating box (1), its characterized in that: the bottom end of the adjusting box (1) is provided with supporting legs (2), the middle part of the lower surface of the adjusting box (1) is provided with a PLC (programmable logic controller) (3), one side of the inner side wall of the adjusting box (1) is fixedly connected with a PH sensor (4), one side of the side wall of the adjusting box (1) far away from the PH sensor (4) is provided with a discharge hole (5), the top wall of the adjusting box (1) is fixedly connected with a bearing (6), an inner ring of the bearing (6) is fixedly connected with a rotating pipe (7) in a sealing manner, two sides of the bottom end of the rotating pipe (7) are connected with two stirring pipes (8), the middle part of the outer surface of the rotating pipe (7) is fixedly connected with a plurality of stirring blades (10), the upper surface of the adjusting box (1) is provided with an air pump (11), an air outlet end of the air pump (11) is fixedly connected with an air outlet pipe (12), one end of the air outlet pipe (12) far away from the air pump (11) is connected with a pipe sleeve (13), add mouth (14) have been seted up on one side of regulating box (1) top, regulating box (1) lateral wall both sides are fixed with two curb plates (15), two curb plate (15) upper surface is fixed with two liquid storage pipes (16), two liquid storage pipe (16) inside sliding connection has two pistons (17), two liquid storage pipe (16) bottom both sides are connected with feed liquor pipe (18) and drain pipe (19) respectively, regulating box (1) both sides top is fixed with two electronic push-and-pull rods (22), two the flexible end of electronic push-and-pull rod (22) is connected with fixed surface respectively on two pistons (17).
2. The pH adjusting device for tropisetron hydrochloride according to claim 1, characterized in that: a plurality of air outlets (9) are formed in the side wall of each stirring pipe (8), and the directions of the air outlets (9) on the stirring pipes (8) are opposite.
3. The pH adjusting device for tropisetron hydrochloride according to claim 1, characterized in that: the top end of the rotating pipe (7) is connected with the pipe sleeve (13) in a sealing and rotating way.
4. The pH adjusting device for tropisetron hydrochloride according to claim 1, characterized in that: feed liquor pipe (18) and drain pipe (19) middle part are equipped with first solenoid valve (20) and second solenoid valve (21) respectively, the one end that liquid storage pipe (16) were kept away from in drain pipe (19) passes regulating box (1) lateral wall and extends to in regulating box (1).
5. The pH adjusting device for tropisetron hydrochloride according to claim 1, characterized in that: the electric push-pull rod (22) and the PH sensor (4) are electrically connected with the PLC (3).
6. The pH adjusting device for tropisetron hydrochloride according to claim 1, characterized in that: the surface of the adjusting box (1) is provided with a visual window (23).
CN202120539487.6U 2021-03-16 2021-03-16 A pH value adjusting device for tropisetron hydrochloride Active CN214552870U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202120539487.6U CN214552870U (en) 2021-03-16 2021-03-16 A pH value adjusting device for tropisetron hydrochloride

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202120539487.6U CN214552870U (en) 2021-03-16 2021-03-16 A pH value adjusting device for tropisetron hydrochloride

Publications (1)

Publication Number Publication Date
CN214552870U true CN214552870U (en) 2021-11-02

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116875435A (en) * 2023-09-06 2023-10-13 碧奥能源(上海)有限公司 Biogas fermentation treatment device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116875435A (en) * 2023-09-06 2023-10-13 碧奥能源(上海)有限公司 Biogas fermentation treatment device
CN116875435B (en) * 2023-09-06 2023-12-08 碧奥能源(上海)有限公司 Biogas fermentation treatment device

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