CN214514570U - Synthetic reation kettle of 2-amino-2-phenylbutyric acid - Google Patents
Synthetic reation kettle of 2-amino-2-phenylbutyric acid Download PDFInfo
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- CN214514570U CN214514570U CN202120451502.1U CN202120451502U CN214514570U CN 214514570 U CN214514570 U CN 214514570U CN 202120451502 U CN202120451502 U CN 202120451502U CN 214514570 U CN214514570 U CN 214514570U
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Abstract
The utility model discloses a synthetic reation kettle of 2-amino-2-phenylbutyric acid, include: the device comprises a synthesis reaction kettle body, a motor, a stirring device, a jacket and a condenser; the motor is arranged at the top of the synthesis reaction kettle body, and the stirring device is arranged in the synthesis reaction kettle body and is connected with the motor; the jacket is sleeved outside the synthesis reaction kettle body; a plurality of feed ports are arranged on one side of the motor at the top of the synthesis reaction kettle body, and a discharge port is arranged at the bottom of the synthesis reaction kettle body; the other side is provided with a condenser. The utility model discloses in be used for the material cooling reflux to the evaporation of being heated in the synthetic cauldron through setting up the condenser, make the interior material of synthetic cauldron fully react, practice thrift the material cost, improve the product yield.
Description
Technical Field
The utility model relates to a chemical production technical field, more specifically the synthetic reation kettle who relates to a 2-amino-2-phenylbutyric acid that says so.
Background
Trimebutine maleate is a specific medicine for irritable bowel syndrome and other gastrointestinal dyskinesia diseases (abdominal pain, nausea, vomit, abdominal fullness and the like), and the medicine can be synthesized and discharged in vitro within 24h to prevent the direct damage to the kidney. Therefore, the mebutine is concerned and advocated at home and abroad as a gastrointestinal motility regulating drug. So far, the synthetic process of trimebutine has a plurality of ways, the common characteristics of which are that an intermediate is firstly generated and then the intermediate is connected into a chain, 2-amino-2-phenylbutyric acid is used as an important intermediate for synthesizing trimebutine, and the preparation process is particularly important.
At present, the yield in the synthesis reaction is low, the materials evaporated by heating can not be recycled, the cost is high, and the operation is complex.
Therefore, how to provide a synthesis reaction kettle with high yield, low cost and simple operation is a problem which needs to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
The utility model discloses aim at solving one of the above-mentioned technical problem among the prior art to a certain extent at least.
To this end, an object of the present invention is to provide a synthesis reaction kettle for 2-amino-2-phenylbutyric acid, comprising: the device comprises a synthesis reaction kettle body, a motor, a stirring device, a jacket and a condenser;
the motor is arranged at the top of the synthesis reaction kettle body, and the stirring device is arranged in the synthesis reaction kettle body and is connected with the motor;
the jacket is sleeved outside the synthesis reaction kettle body;
a plurality of feed ports are formed in one side of the motor at the top of the synthesis reaction kettle body, and a discharge port is formed in the bottom of the synthesis reaction kettle body; the other side is provided with a condenser.
The utility model has the advantages that: the utility model discloses in be used for the material cooling reflux to the evaporation of being heated in the synthetic cauldron through setting up the condenser, make the interior material of synthetic cauldron fully react, practice thrift the material cost, improve the product yield.
Preferably, the jacket is provided with a jacket feeding pipe and a jacket discharging pipe, the jacket feeding pipe is arranged on the upper part of the outer side wall of the jacket, and the jacket discharging pipe is arranged on the lower part of the outer side wall of the heating jacket.
Preferably, a nitrogen purge pipe is arranged on the jacket feed pipe.
Adopt above-mentioned technical scheme's beneficial effect: the nitrogen purging pipe is arranged on the jacket, so that the jacket feeding pipe can also be used as a circulating water pipe, the jacket can be heated and cooled, and the cost of the device is saved.
Preferably, a backflow discharge pipe and a backflow feed pipe are arranged on one side, away from the feed port, of the top of the synthesis reaction kettle body, of the motor; the backflow discharge pipe is arranged between the backflow feed pipe and the motor;
the one end that synthetic reation kettle body was kept away from to the backward flow discharging pipe with the bottom of condenser is connected, the one end that synthetic reation kettle body was kept away from to the backward flow inlet pipe with the top of condenser is connected.
Preferably, the upper part of the side wall of the condenser is provided with a circulating water outlet, and the lower part of the side wall of the condenser is provided with a circulating water inlet.
Adopt above-mentioned technical scheme's beneficial effect: each part provided with a reflux program is used for ensuring the full reaction of the materials in the reaction kettle, thereby saving the material cost
Preferably, the stirring device comprises a stirring shaft and a stirring blade, one end of the stirring shaft is connected with the motor, and the other end of the stirring shaft is connected with the stirring blade.
Preferably, a feeding valve is arranged on the feeding port, and a discharging valve is arranged on the discharging port.
According to the technical scheme, compared with the prior art, the utility model discloses a synthesis reaction kettle of 2-amino-2-phenylbutyric acid, the parts such as the condenser and the reflux pipeline for reflux are arranged to ensure that the materials evaporated by heating in the synthesis reaction kettle are cooled and refluxed to be fully utilized, so that the cost is reduced, and the materials can be ensured to be fully reacted; the nitrogen purging pipe is arranged, so that the jacket feeding pipe can also be used as a circulating water pipe, the jacket can be heated and cooled, and the cost of the device is saved; moreover, the utility model provides a synthetic reation kettle simple structure, easy operation.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic structural view provided by the present invention;
the device comprises a synthesis reaction kettle body 1, a synthesis reaction kettle body 2, a motor 3, a stirring shaft 4, stirring blades 5, a jacket 6, a backflow discharging pipe 7, a condenser 8, a backflow feeding pipe 9, a feeding port 10, a discharging port 11, a jacket feeding pipe 12, a jacket discharging pipe 13, a circulating water outlet 14, a circulating water inlet 15, a feeding valve 16, a discharging valve 17 and a nitrogen purging pipe.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
The embodiment of the utility model discloses synthetic reation kettle of 2-amino-2-phenylbutyric acid, include: the device comprises a synthesis reaction kettle body 1, a motor 2, a stirring device, a jacket 5 and a condenser 7;
the motor 2 is arranged at the top of the synthesis reaction kettle body 1, and the stirring device is arranged in the synthesis reaction kettle body 1 and is connected with the motor 2;
the jacket 5 is sleeved outside the synthesis reaction kettle body 1;
a plurality of feed ports 9 are arranged on one side of the motor 2 at the top of the synthesis reaction kettle body 1, and a discharge port 10 is arranged at the bottom; the other side is provided with a condenser 7.
In one embodiment, the jacket 5 is provided with a jacket feed pipe 11 and a jacket discharge pipe 12, the jacket feed pipe 11 is provided on the upper portion of the outer side wall of the jacket 5, and the jacket discharge pipe 12 is provided on the lower portion of the outer side wall of the heating jacket 5. A nitrogen purge pipe 17 for purging nitrogen was provided to the jacket feed pipe 11. Hot water is injected into the jacket 5 through the jacket feeding pipe 11, the nitrogen purging pipe 17 is arranged on the jacket 5, so that the jacket feeding pipe 11 for injecting the hot water can also be used as a circulating water pipe, the temperature of the jacket 5 can be raised and lowered, and the cost of the device is saved.
In one embodiment, a reflux discharge pipe 6 and a reflux feed pipe 8 are arranged on one side of the top of the synthesis reaction kettle body 1, which is far away from a feed port 9, of the motor 2; the backflow discharging pipe 6 is arranged between the backflow feeding pipe 8 and the motor 2;
the one end that synthetic reation kettle body 1 was kept away from to backward flow discharging pipe 6 is connected with the bottom of condenser 7, and the one end that synthetic reation kettle body 1 was kept away from to backward flow inlet pipe 8 is connected with the top of condenser 7.
The upper part of the side wall of the condenser 7 is provided with a circulating water outlet 13, and the lower part is provided with a circulating water inlet 14.
The parts for the cooling reflux program are arranged to enable the heated and evaporated materials to reflux and ensure the materials in the reaction kettle to fully react, so that the material cost is saved.
In one embodiment, the stirring device comprises a stirring shaft 3 and a stirring blade 4, wherein one end of the stirring shaft 3 is connected with the motor 2, and the other end is connected with the stirring blade 4.
In one embodiment, two material inlets 9 are provided, and each material inlet 9 is provided with a material inlet valve 15, and the material outlet 10 is provided with a material outlet valve 16.
The synthesis reaction kettle of the 2-amino-2-phenylbutyric acid provided by the utility model controls the amount of the fed materials and the final products by opening and closing the feed valve 15 and the discharge valve 16; the amount of hot water added is controlled by a jacket feed pipe 11 and a jacket discharge pipe 12, so that the materials in the synthesis reaction kettle can be fully reacted at a certain temperature; in the material reaction process in the synthesis reaction kettle, materials evaporated by heating enter the condenser 7 through the backflow discharge pipe 6 to be cooled and flow back to the synthesis reaction kettle through the backflow feed pipe 8, so that the material cost is saved, and the product yield can be improved; the nitrogen purging pipe 17 is arranged on the jacket feeding pipe 11, the jacket feeding pipe 11 can also be used as a circulating water pipe through nitrogen purging, the jacket 5 can be heated and cooled, and the cost of the device is saved.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples described in this specification can be combined and combined by those skilled in the art.
Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art without departing from the scope of the present invention.
Claims (7)
1. A synthetic reation kettle of 2-amino-2-phenylbutyric acid is characterized by comprising: the device comprises a synthesis reaction kettle body, a motor, a stirring device, a jacket and a condenser;
the motor is arranged at the top of the synthesis reaction kettle body, and the stirring device is arranged in the synthesis reaction kettle body and is connected with the motor;
the jacket is sleeved outside the synthesis reaction kettle body;
a plurality of feed ports are formed in one side of the motor at the top of the synthesis reaction kettle body, and a discharge port is formed in the bottom of the synthesis reaction kettle body; the other side is provided with a condenser.
2. The kettle of claim 1, wherein the jacket is provided with a jacket feeding pipe and a jacket discharging pipe, the jacket feeding pipe is arranged on the upper portion of the outer side wall of the jacket, and the jacket discharging pipe is arranged on the lower portion of the outer side wall of the jacket.
3. A synthesis reactor of 2-amino-2-phenylbutyric acid according to claim 2, wherein a nitrogen purge is provided to the jacketed feed pipe.
4. The synthesis reaction kettle of 2-amino-2-phenylbutyric acid according to claim 1, wherein a reflux discharge pipe and a reflux feed pipe are arranged on one side of the top of the synthesis reaction kettle body, which is far away from a feeding port, of a motor; the backflow discharge pipe is arranged between the backflow feed pipe and the motor;
the one end that synthetic reation kettle body was kept away from to the backward flow discharging pipe with the bottom of condenser is connected, the one end that synthetic reation kettle body was kept away from to the backward flow inlet pipe with the top of condenser is connected.
5. A synthesis reaction kettle of 2-amino-2-phenylbutyric acid according to claim 4, wherein the upper part of the side wall of the condenser is provided with a circulating water outlet, and the lower part is provided with a circulating water inlet.
6. The synthetic reaction kettle of 2-amino-2-phenylbutyric acid according to claim 1, wherein the stirring device comprises a stirring shaft and a stirring blade, one end of the stirring shaft is connected with the motor, and the other end of the stirring shaft is connected with the stirring blade.
7. The kettle of claim 1, wherein a feed valve is disposed on the feed port, and a discharge valve is disposed on the discharge port.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120451502.1U CN214514570U (en) | 2021-03-02 | 2021-03-02 | Synthetic reation kettle of 2-amino-2-phenylbutyric acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120451502.1U CN214514570U (en) | 2021-03-02 | 2021-03-02 | Synthetic reation kettle of 2-amino-2-phenylbutyric acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214514570U true CN214514570U (en) | 2021-10-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202120451502.1U Active CN214514570U (en) | 2021-03-02 | 2021-03-02 | Synthetic reation kettle of 2-amino-2-phenylbutyric acid |
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| Country | Link |
|---|---|
| CN (1) | CN214514570U (en) |
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2021
- 2021-03-02 CN CN202120451502.1U patent/CN214514570U/en active Active
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