CN214486837U

CN214486837U - 2- (2- (2-aminoethoxy) ethoxy) acetate preparation device

Info

Publication number: CN214486837U
Application number: CN202120252356.XU
Authority: CN
Inventors: 李小军
Original assignee: Anqing Ruisheng Pharmaceutical Technology Co ltd
Current assignee: Anqing Ruisheng Pharmaceutical Technology Co ltd
Priority date: 2021-01-27
Filing date: 2021-01-27
Publication date: 2021-10-26
Anticipated expiration: 2031-01-27

Abstract

The utility model discloses a 2- (2- (2-aminoethoxy) ethoxy) acetate salification preparation facilities, including the compounding ring canal, the intracavity fixedly connected with compounding part of compounding ring canal. Be equipped with vibration hybrid module on the compounding ring canal, vibration hybrid module includes the vibration disk body with the concentric setting of compounding ring canal, the top center part of vibration disk body is equipped with vibrating motor, the lateral wall of compounding ring canal is contradicted on the dish outline of vibration disk body, the top fixedly connected with a plurality of assembly parts of vibration disk body, the bottom intercommunication of compounding ring canal has row's material pipe part, there is row's material pipe part joint at the bottom edge position of vibration disk body. Adopt above-mentioned device part design to realize in material salification in-process, realize the hydrochloric acid solution for the preparation now, and above-mentioned device part design has avoided traditional mode configuration hydrochloric acid to lead to allotment cauldron corroded technical defect.

Description

2- (2- (2-aminoethoxy) ethoxy) acetate preparation device

Technical Field

The utility model relates to a 2- (2- (2-aminoethoxy) ethoxy) acetate preparation facilities field especially relates to is 2- (2- (2-aminoethoxy) ethoxy) acetate preparation facilities.

Background

The 2- (2- (2-aminoethoxy) ethoxy) acetate synthesis device is a pharmaceutical and chemical intermediate which is relatively commonly used, has relatively wide application in the pharmaceutical and chemical preparation process, and has the following structural general formula:

in the industrial synthesis and processing of the intermediate, particularly in the hydrochloride salt forming process, concentrated hydrochloric acid is often used, and the hydrochloric acid can be dripped into a reaction kettle after being diluted. Therefore, hydrochloric acid is diluted by a solvent and then prepared into a diluted hydrochloric acid solvent, and then the diluted hydrochloric acid solvent is dripped in a mode often adopted in the prior art.

The disadvantages of the above method are: the preparation method needs to be carried out in advance, and cannot be realized in the synthesis of intermediate materials. The specific reasons are that: the prior art does not disclose a material preparation device that can be prepared as it is.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the technical problem of providing a preparation device of 2- (2- (2-aminoethoxy) ethoxy) acetate.

The utility model discloses a solve above-mentioned technical problem through following technical scheme:

the 2- (2- (2-aminoethoxy) ethoxy) acetate synthesis device comprises a mixing ring pipe, wherein one side of the mixing ring pipe is communicated with a material solution feeding pipe, and the opposite side of the mixing ring pipe is communicated with a diluting solvent material pipeline;

a mixing part is fixedly connected in the tube cavity of the mixing ring tube and used for mixing materials;

the mixing ring pipe is provided with a vibration mixing component;

the vibration mixing component comprises a vibration disc body concentrically arranged with the material mixing ring pipe, a vibration motor is assembled at the center of the top of the vibration disc body, and the side wall of the material mixing ring pipe is abutted against the contour of the vibration disc body;

the top of the vibration disc body is fixedly connected with a plurality of assembly parts;

the bottom of the mixing ring pipe is communicated with a discharge pipe part, and the discharge pipe part is used for discharging materials;

arrange the material pipe part and include main pipe body portion, the top intercommunication of main pipe body portion has the pipe body portion of buckling that a plurality of slope set up, the pipe body portion of buckling intercommunication main pipe body portion, the spacing mouth that a plurality of annular array distributes is seted up at the bottom edge position of vibration disk body, the pipe body portion joint of buckling is on spacing mouthful.

Preferably, the mixing part comprises an annular rod, a plurality of annularly distributed guide mixing pieces are fixedly connected in the annular rod, and the guide mixing pieces are fixedly connected to the inner wall of the tube cavity of the mixing ring tube;

the flow guide mixing piece is provided with a plurality of flow guide holes;

the bottom of the main pipe body part is communicated with a material dispersing assembly.

Preferably, the assembly part comprises a first mounting rod fixedly connected to the edge of the top of the vibration disc body, the first mounting rod is connected with a second mounting rod in an assembling manner, and the second mounting rod is fixedly connected to the top of the reaction kettle.

Preferably, a plurality of clamping pieces distributed in an annular array are fixedly connected to the disc outline of the vibration disc body, each clamping piece comprises a threaded rod fixedly connected to the vibration disc body, a clamping plate is fixedly connected to the threaded rod, and a clamping groove is formed in the clamping plate;

the threaded rod is provided with a hexagonal adjusting bulge.

Preferably, the shape of the guide mixing piece is circular;

the diversion material mixing pieces are obliquely arranged.

Preferably, the angle of the inclined diversion mixing piece is 15 degrees;

the material of water conservancy diversion material mixing piece, ring body pole is the polytetrafluoroethylene material.

Preferably, the bottom of the main pipe body part is communicated with a drainage pipeline vertically arranged downwards;

the material dispersing assembly is communicated with the liquid discharge pipeline.

Preferably, the material dispersion assembly comprises a plurality of liquid discharge spheres arranged at intervals up and down, a cavity is formed in each liquid discharge sphere, and a plurality of liquid discharge small holes are formed in each liquid discharge sphere.

Preferably, a valve is fitted to the drain line.

Preferably, the drainage ball is made of polytetrafluoroethylene.

Compared with the prior art, the utility model has the following advantages:

the utility model relates to a 2- (2- (2-aminoethoxy) ethoxy) acetate synthesizer, through designing the compounding ring canal, one side of the compounding ring canal is communicated with a material solution feeding pipe, the opposite side of the compounding ring canal is communicated with a diluent material pipeline, a compounding part is fixedly connected in the lumen of the compounding ring canal, the compounding part is used for compounding, and a vibration mixing component is assembled on the compounding ring canal; realize the dilution of the vibration mixed material.

Through the design vibration hybrid module include with the concentric vibration disk body that sets up of compounding ring canal, the top central point of vibration disk body is equipped with vibrating motor, the lateral wall of compounding ring canal is contradicted on the profile of vibration disk body, the bottom intercommunication of the top fixedly connected with a plurality of assembly parts of vibration disk body, compounding ring canal has row pipe spare, it is used for row material, row's material pipe spare to arrange the material pipe spare and includes main pipe body portion, the top intercommunication of main pipe body portion has the bent pipe body portion that a plurality of slope set up, bent pipe body portion intercommunication main pipe body portion, the spacing mouth that a plurality of annular array distributes is seted up to the bottom edge position of vibration disk body, bent pipe body portion joint is on spacing mouthful. The hydrochloric acid solution of the material for preparation is realized.

Adopt above-mentioned device part design to realize that whole device installs on reation kettle, at material salification in-process, realize the hydrochloric acid solution for the present preparation, avoided the pre-configuration, simultaneously, adopt above-mentioned device part design convenient operation not only, improved the production efficiency of material processing, and above-mentioned device part design has avoided traditional mode configuration hydrochloric acid to lead to allotting the technical defect that the cauldron corrodes.

Drawings

Fig. 1 is a schematic view of a decentralized architecture according to an embodiment of the present invention;

FIG. 2 is a schematic structural view of a vibratory mixing assembly in an embodiment of the invention;

FIG. 3 is a schematic view of the dispersing structure of the mixing collar according to an embodiment of the present invention;

FIG. 4 is a schematic structural diagram of a material mixing component in an embodiment of the present invention;

FIG. 5 is a schematic structural diagram of an embodiment of the invention;

fig. 6 is a schematic view of the overall structure of the embodiment of the present invention in fig. 1;

FIG. 7 is a schematic view of a retainer according to an embodiment of the present invention;

fig. 8 is a schematic structural view of the clamping member connected with the vibrating plate body in the embodiment of the present invention.

Detailed Description

The embodiments of the present invention will be described in detail below, and the present embodiment is implemented on the premise of the technical solution of the present invention, and a detailed implementation manner and a specific operation process are given, but the scope of the present invention is not limited to the following embodiments.

As shown in fig. 1-8, a device for preparing 2- (2- (2-aminoethoxy) ethoxy) acetate comprises a mixing loop 1, wherein one side of the mixing loop 1 is communicated with a material solution feeding pipe 12, and the opposite side of the mixing loop 1 is communicated with a diluent solvent material pipeline 11, specifically, the left side of the top of the mixing loop 1 is communicated with the material solution feeding pipe 12, and the right side of the top of the mixing loop 1 is communicated with the diluent solvent material pipeline 11.

The material solution feeding pipe 12 and the diluent solvent material pipeline 11 are communicated to an external material supply pipeline through an assembly flange. Material solution specifically is strong hydrochloric acid solution and adds from material solution filling tube 12, and dilution solvent is from 11 pipeline additions of dilution solvent material pipeline and compounding in compounding ring canal 1, and in order to realize diluting above-mentioned solution compounding, the intracavity fixedly connected with compounding part 4 of above-mentioned compounding ring canal 1. The mixing part 4 is used for mixing.

To improve the mixing effect, the mixing loop is provided with a vibrating mixing unit 5.

The specific structure of the vibrating mixing assembly 5 is as follows: the vibrating and mixing assembly 5 comprises a vibrating disk body 51 concentrically arranged with the mixing ring, a vibrating motor 52 is arranged at the center of the top of the vibrating disk body 51, and the side wall of the mixing ring is abutted against the outline of the vibrating disk body 51.

Simultaneously, in order to realize the assembly of vibration disk body 51, the top fixedly connected with of above-mentioned vibration disk body 51 has a plurality of assembly parts, and concrete mode is: the assembly part comprises a first mounting rod 6 fixedly connected to the edge of the top of the vibration disc body 51, the first mounting rod 6 is connected with a second mounting rod 61 in an assembling mode, and the second mounting rod 61 is fixedly connected to the top of the reaction kettle. The second mounting rod 61 is fixedly connected to the top of the reaction kettle, and the assembly is realized in this way.

The bottom of the mixing ring pipe 1 is communicated with a discharge pipe component; specifically, arrange row material pipe part and include main somatic part 2, the top intercommunication of main somatic part 2 has the bending tube body portion 21 that a plurality of slope set up, bending tube body portion 21 intercommunication main somatic part 2.

After being mixed, the materials enter the bent pipe body part 21 and the main pipe body part 2.

Correspondingly, the bottom edge of the vibrating plate body 51 is provided with a plurality of limit openings 511 distributed in an annular array, and the bent tube body 21 is clamped on the limit openings 511.

Open vibrating motor 52, this moment, vibrating motor 52 with the vibration can conduct to vibration disk body 51 on, and then contradict the vibration of compounding ring canal 1 on vibration disk body 51, simultaneously, the card is followed the vibration at the body portion of buckling of vibration disk body 51 bottom, because material solution is in compounding ring canal 1, therefore material solution fully mixes the material and dilutes under the vibration.

In the actual working process, in order to realize vibration according to the radius of different mixing ring pipes 1, a plurality of clamping pieces distributed in an annular array are fixedly connected to the overall profile of the vibration disc body 51, each clamping piece comprises a threaded rod 71 fixedly connected to the vibration disc body 51, a clamping plate 7 is fixedly connected to the threaded rod 71, and a clamping groove is formed in the clamping plate 7. The threaded rod 71 is provided with a hexagonal adjusting protrusion.

Realize cardboard and vibration disk body 51's interval through adjusting threaded rod 71 and adjust, realize compounding ring canal 1 joint in the draw-in groove, and then realize the vibration conduction.

Above-mentioned structural design realizes that the assembly is contradicted on vibration disk body 51 to the compounding ring canal 1 realization that the size is little, and the vibration compounding of being convenient for is diluted.

In order to realize the sufficient mixing and dilution of the solution, a mixing part 4 is fixedly connected in the tube cavity of the mixing ring pipe 1; the mixing component 4 comprises an annular rod 41, a plurality of annularly distributed guide mixing pieces 42 are fixedly connected in the annular rod 41, and the guide mixing pieces 42 are fixedly connected on the inner wall of the tube cavity of the mixing ring tube 1; the diversion material mixing piece 42 is provided with a plurality of diversion holes 421.

Specifically, the diversion material mixing pieces 42 are circular; the diversion mixing material piece 42 is arranged obliquely. The guide mixing piece 42 is obliquely arranged at an angle of 15 degrees. The diversion material mixing piece 42 and the ring body rod 41 are made of polytetrafluoroethylene materials.

Because the inclined angle of the diversion mixing piece 42 is 15 degrees, a gap for solution to pass through is formed between the diversion mixing piece 42 and the mixing ring pipe 1.

After the solution enters, the hydrochloric acid solution and the solvent move towards each other from two sides respectively, and the hydrochloric acid solution and the solvent are fully and slowly mixed with each other under the action of the diversion material mixing piece 42. The flow-guiding mixing piece 42 serves as a channel for dividing the solution into a plurality of mixing channels, thereby realizing sufficient mixing.

The bottom of the main pipe body part 2 is communicated with a material dispersing assembly. In the actual working process, the material dispersing component is positioned in the reaction kettle, specifically, the bottom of the main pipe body part 2 is communicated with a liquid discharge pipeline 22 which is vertically arranged downwards (the liquid discharge pipeline 22 is provided with a valve 221, in the process of mixing hydrochloric acid, the valve 221 is closed, and the valve 221 is positioned outside the reaction kettle); a drain 22 runs through the reactor.

The material dispersion assembly communicates with a drain line 22.

The material dispersion subassembly includes flowing back spheroid 3 that the interval set up about a plurality of, it has the cavity to open in the flowing back spheroid 3, a plurality of flowing back aperture has been seted up on the flowing back spheroid 3.

The material of the liquid discharge ball 3 is polytetrafluoroethylene.

The material solution is discharged from the liquid discharge ball body 3, and the design mode avoids the overlarge concentration of the local hydrochloric acid solution in the reaction kettle.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims

The device for synthesizing the 2- (2- (2-aminoethoxy) ethoxy) acetate is characterized by comprising a mixing ring pipe, wherein one side of the mixing ring pipe is communicated with a material solution feeding pipe, and the opposite side of the mixing ring pipe is communicated with a diluting solvent material pipeline;

a mixing part is fixedly connected in the tube cavity of the mixing ring tube and used for mixing materials;

the mixing ring pipe is provided with a vibration mixing component;

the vibration mixing component comprises a vibration disc body concentrically arranged with the material mixing ring pipe, a vibration motor is assembled at the center of the top of the vibration disc body, and the side wall of the material mixing ring pipe is abutted against the contour of the vibration disc body;

the top of the vibration disc body is fixedly connected with a plurality of assembly parts;

the bottom of the mixing ring pipe is communicated with a discharge pipe part, and the discharge pipe part is used for discharging materials;

arrange the material pipe part and include main pipe body portion, the top intercommunication of main pipe body portion has the pipe body portion of buckling that a plurality of slope set up, the pipe body portion of buckling intercommunication main pipe body portion, the spacing mouth that a plurality of annular array distributes is seted up at the bottom edge position of vibration disk body, the pipe body portion joint of buckling is on spacing mouthful.
2. The apparatus according to claim 1, wherein the mixing member comprises a ring rod, a plurality of annularly distributed diversion mixing sheets are fixedly connected in the ring rod, and the diversion mixing sheets are fixedly connected to the inner wall of the tube cavity of the mixing ring;

the flow guide mixing piece is provided with a plurality of flow guide holes;

the bottom of the main pipe body part is communicated with a material dispersing assembly.
3. The apparatus according to claim 2, wherein the assembly member comprises a first mounting rod fixedly connected to the top edge of the vibrating plate, and a second mounting rod fixedly connected to the top of the reaction vessel is connected to the first mounting rod.
4. The apparatus according to claim 3, wherein the vibrating plate has a plurality of clamping members fixedly attached to a contour of the vibrating plate, each clamping member comprising a threaded rod fixedly attached to the vibrating plate, a clamping plate fixedly attached to the threaded rod, and a clamping slot formed in the clamping plate;

the threaded rod is provided with a hexagonal adjusting bulge.
5. The apparatus according to claim 4, wherein the inducer is circular in shape;

the diversion material mixing pieces are obliquely arranged.
6. The apparatus according to claim 5, wherein the inducer is inclined at an angle of 15 degrees;

the material of water conservancy diversion material mixing piece, ring body pole is the polytetrafluoroethylene material.
7. The apparatus according to claim 6, wherein the main body portion has a bottom portion connected to a drain line vertically disposed downward;

the material dispersing assembly is communicated with the liquid discharge pipeline.
8. The apparatus according to claim 7, wherein the material dispersing unit comprises a plurality of drainage balls spaced apart from each other, the drainage balls having cavities therein, and the drainage balls having drainage holes therein.
9. The apparatus according to claim 8, wherein a valve is provided in the drain line.
10. The apparatus according to claim 9, wherein the drainage ball is made of polytetrafluoroethylene.