CN214485309U - Shielding device for batch experiment animal any part ionizing radiation irradiation - Google Patents

Abstract

The utility model discloses a shielding device for batch carrying out ionizing radiation irradiation on any part of an experimental animal, which comprises an animal fixing part and a ray shielding part; the animal fixing part comprises an animal anesthesia fixing table, and the ray shielding part comprises a ray shielding table; an anesthesia induction box and a batch animal fixing box are arranged on the tabletop of the animal anesthesia fixing table; a transverse regulating and shielding device, an upper and lower regulating and shielding device and a transverse and longitudinal scale dividing plate are arranged on the table top of the ray shielding table; the transverse regulation shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground; the up-down regulation shielding device blocks redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position is exposed in the direction of the horizontal ground; a rectangular area formed at the intersection of the two gaps is the irradiation field; the stepped connection is used for blocking the leakage caused by the fact that rays pass through the transverse arrangement position of the shielding blocks, and incomplete blocking is avoided.

Description

Shielding device for batch experiment animal any part ionizing radiation irradiation

Technical Field

The utility model belongs to the basic medical science scientific research field, concretely relates to a shield assembly and method that is used for carrying out experimental animals arbitrary position ionizing radiation in batches and shines.

Background

Ionizing radiation plays an increasingly important role in human production and life, is widely applied to medical treatment (such as tumor radiotherapy, medical imaging and the like), industrial flaw detection, agricultural breeding, nuclear power stations, national defense and military industry fields (such as nuclear weapons) and the like, and brings great assistance to national economic development. However, these widely existing nuclear and radiation devices cause various damages to human body if they are not managed well and operated incorrectly; in the process of clinically diagnosing and treating diseases by using ionizing radiation, how to maximally relieve complications while exerting the optimal treatment effect also has very important clinical significance. Therefore, the research on radiation damage medical protection, the improvement of tumor radiotherapy effect and the like has very important practical significance, and the radiobiological research is the basis for promoting the development of the problems and is the important focus of attention for a long time.

In the process of a specific radiation biology basic experiment irradiation link, the development efficiency of local irradiation of an experimental animal plays an important role, and the development efficiency relates to radiotherapy simulation of tumor in-vivo research, modeling of local tissue radiation damage and the like, so that the manufacture of a local irradiation shielding device capable of meeting the experiment requirements is very important. However, the conventional similar devices have many defects, and it is difficult to meet the actual use requirements, which mainly appear as follows: 1 because the compliance of the experimental animal is poor, the body position fixing position is difficult to keep unchanged, and effective fixing is needed. The traditional method is to inject chloral hydrate and other anesthetics into the abdominal cavity for anesthesia, although the basic anesthetic effect can be achieved, the excessive anesthesia is easy to cause the accidental death of animals, and the injected medicine has potential influence on certain detection indexes. 2, regarding the fixing mode, the traditional method comprises a clamping mode, a hole mode and the like, wherein the clamping mode is used for clamping the main joints of the animals by using a clamp, so that blood circulation is easily influenced, and secondary injuries such as ischemia reperfusion injury and even unsmooth peripheral circulation are caused; the latter can only fix animals of specific size and shape, and the fixation is incomplete, easy to loosen and difficult to operate. The reliable method which is simple and feasible and is firmly fixed is found to be very important. With respect to shielding, the conventional method is to shield the area to be shielded with a certain thickness of high electron density (high atomic number) material such as lead. The position needs to be arranged in advance as required every time, the operation is difficult, and the precision of the position and the area is difficult to achieve. Because lead has high weight and certain toxicity, the operability is poor, and a shielding device with accurate shielding position and strong operability is urgently needed to be designed. Through research, most of the previous similar products are fixed open-hole lead blocks, only can transmit rays aiming at fixed positions and areas, have single function and low cost performance, and are difficult to meet different experimental requirements. Therefore, the development of a novel multifunctional ionizing radiation shielding device with high operability is urgent. 4 when the small animal X-ray radiotherapy instrument is matched with a collimator and other devices for positioning irradiation, only one individual can be operated at a time. Most of the prior similar products can not realize large-batch and expandable accurate regional local irradiation. Because the space and time of the irradiation field are precious, and the interference to the experiment is increased due to the overlong waiting time, the experiment efficiency and the experiment precision can be greatly improved by researching and manufacturing a large batch of irradiation devices. 5, designing and developing a new module aiming at the difficulties, organically integrating different module mechanisms, and comprehensively considering all comprehensive performances such as structural strength, volume optimization, operability and the like, which is also a technical difficulty to be considered emphatically at present. In conclusion, the ionizing radiation local shielding device has the advantages of rich development functions, simplicity in operation, reliability in fixation and small influence on an experimental object, and has very important practical significance. Due to the great research and development difficulty, the method becomes a hardware bottleneck restricting scientific research in related fields at present, and is a great problem to be solved urgently in the industry.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to current defect, provide a shield assembly that is used for carrying out experimental animals arbitrary position ionizing radiation in batches and shines to realize shining the quick big batch operation of process, and guarantee to shine regional position and area nimble adjustable, the accuracy shines.

The technical scheme of the utility model is that: the shielding device for batch ionizing radiation irradiation of any part of experimental animals comprises an animal fixing part and a ray shielding part; the animal fixing part comprises an animal anesthesia fixing table, the ray shielding part comprises a ray shielding table, and a detachable connecting mechanism is arranged at the corresponding joint of the right side of the animal anesthesia fixing table and the left side of the ray shielding table;

an anesthesia induction box and a batch animal fixing box are arranged on the tabletop of the animal anesthesia fixing table; the anesthesia induction box is used for pre-anesthetizing the animal before fixing, increasing the compliance, and then transferring the experimental animal to an irradiation chamber for effective fixing. The batch animal fixing box is arranged at the rightmost end of the tabletop of the animal anesthesia fixing table, and an animal fixing device capable of fixing experimental animals in batches and horizontal and longitudinal scale dividing lines are arranged on one side surface of the batch animal fixing box facing the ray shielding table;

A transverse regulation and control shielding device capable of exposing a first gap with adjustable size and position in the direction vertical to the ground, an up-down regulation and control shielding device capable of exposing a second gap with adjustable size and position in the direction horizontal to the ground and a transverse-longitudinal scale division plate are arranged on the table top of the ray shielding table; the horizontal and vertical scale dividing lines on the horizontal and vertical scale dividing plate are completely consistent with the horizontal and vertical scale dividing lines on the batch animal fixing boxes;

and a rectangular area formed at the intersection of the first gap and the second gap is the irradiation field.

Furthermore, the transverse regulation and control shielding device comprises a bottom frame and a vertical shielding block splicing group;

the vertical shielding block splicing group comprises 2 vertical side baffles, a plurality of vertical middle baffles and a plurality of standby vertical baffles; the vertical side baffle is vertically arranged, and the upper half part or the lower half part of one side surface of the board surface integrally protrudes towards the outside; the upper half part of one side surface of the plate surface of the vertical middle baffle plate protrudes towards the outside, and the lower half part of the other side surface of the plate surface of the vertical middle baffle plate protrudes towards the outside; the vertical middle baffles in the middle and the vertical side baffles at two sides are sequentially spliced along the front and back direction to form a sealed block-shaped whole; the standby vertical baffle has the same structure as the vertical side baffle; after one or more vertical middle baffles in the middle are extracted from bottom to top, the spare vertical baffles are adopted for filling, so that the transverse regulation and control shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground;

The vertical shielding block splicing group is placed on the bottom frame, and a gap is formed in the contact surface of the bottom frame and the vertical shielding block splicing group along the front-back direction;

furthermore, the up-down regulation and control shielding device comprises 2 transverse side baffles, a plurality of transverse middle baffles, a plurality of standby transverse baffles and a plurality of standby gaskets; the transverse side baffle is horizontally arranged, and the left half part or the right half part of one side surface of the board surface integrally protrudes towards the outside; the left half part of one side surface of the plate surface of the transverse middle baffle plate protrudes towards the outside, and the right half part of the other side surface of the transverse middle baffle plate protrudes towards the outside; a plurality of transverse middle baffles in the middle and transverse side baffles at the upper and lower sides are sequentially spliced from bottom to top to form a sealed blocky whole; the spare transverse baffle has the same structure as the transverse side baffle; the gasket comprises a plurality of transverse side baffle gaskets, a plurality of transverse middle baffle gaskets and a plurality of standby transverse baffle gaskets; the transverse side baffle plate gasket and the spare transverse baffle plate gasket have the same structure with the transverse side baffle plate but have narrower front and back sizes, and the transverse middle baffle plate gasket has the same structure with the transverse middle baffle plate but have narrower front and back sizes; a plurality of transverse middle baffle gaskets in the middle and transverse side baffle gaskets at the upper side and the lower side are sequentially spliced from bottom to top to form a sealed block-shaped whole; after one or more middle transverse middle baffles are extracted from the front and back direction, the spare transverse baffles are adopted for filling, and gasket blocks with corresponding thicknesses are matched for supporting and blocking at two sides, so that the up-and-down regulation shielding device blocks redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position in the direction of the horizontal ground is exposed;

The intersection of the first gap and the second gap forms a rectangular area which is the irradiation field.

Furthermore, a plurality of anaesthetic masks are further arranged on one side face of the batch of animal fixing boxes facing the ray shielding table, one anaesthetic mask is correspondingly matched with one animal fixing point, and after the animal is fixed, a gas outlet of the anaesthetic mask is positioned at the position of the mouth and the nasal cavity of the animal. The anaesthetic mask is provided to prevent an animal which has been pre-anaesthetised from becoming prematurely awakened and affecting the immobilisation operation and effect when immobilising it. Each animal corresponds to a mask, anesthetic gas is sprayed out from the mask to form local higher concentration, and the excessive influence on the environment is controlled by adjusting the flow, so that an operator can accurately fix the animals.

Furthermore, the bottom of the desktop of the animal anesthesia fixing table is provided with an anesthesia device with an animal anesthesia machine, and an anesthesia gas output pipeline of the anesthesia device is connected to an anesthesia induction box and an anesthesia mask.

The anesthesia device comprises a compressed air tank, a safety valve, an anesthesia evaporator, a gas supply delivery valve, a breathing loop, an air passage pressure gauge, a gas regulating valve, a waste gas absorption tank and the like, and the compressed air tank is adopted, so that the physical and chemical properties of the electronic material are influenced after the electronic material is irradiated by ionizing radiation for a long time, and electronic components such as an electric air pump and the like are avoided and selected to replace the electronic material.

Further, animal fixing device is including paving the fixed box of batch animal towards thread gluing plain noodles and a plurality of thread gluing hair side on the ray shielding table side, thread gluing hair side can be fixed the whole sticking of animal between thread gluing plain noodles and thread gluing hair side. And then the body position is flexibly fixed by using small wool noodles, so that the part needing to be irradiated is ensured to be in the irradiation field. The anesthesia masks matched with the animals one by one can also be fixed at the positions of the mouth and the nasal cavity of the animals through sticky buckle hair attaching surfaces.

Furthermore, a shielding block baffle is arranged on the right side of the anesthesia device. Excessive unnecessary radiation exposure of the anesthesia apparatus is avoided as much as possible.

Furthermore, the anesthesia induction box is made of transparent materials.

Furthermore, the transverse regulation shielding device and the up-down regulation shielding device are arranged at the leftmost side of the ray shielding table, and the transverse regulation shielding device and the up-down regulation shielding device are arranged at the leftmost side of the ray shielding table. The batch of animal fixing boxes are designed to be tightly attached to the exposed opening of the shielding part, and possible regional diffusion deviation of non-parallel ray components after the collimation effect of the components penetrating through the pore channels is reduced.

Furthermore, the bottom support rods of the animal anesthesia fixing table and the ray shielding table are telescopic rods with adjustable heights; and the animal anesthesia fixing table and the ray shielding table are both provided with gradienters. The height-adjustable supporting rod is adopted, so that the horizontal irradiation height range of an irradiation source can be covered; the horizontal desktop of each part is assembled with a level gauge, so that the desktop is horizontal after the height of the supporting rod is adjusted, and the accuracy of the experiment is ensured.

Furthermore, universal wheels capable of being locked automatically are arranged at the bottoms of the animal anesthesia fixing table and the ray shielding table. The animal anesthesia fixing table can be moved out of the irradiation chamber during the preparation period of animal irradiation, so that an operator can conveniently perform anesthesia, fixation and recording on animals in advance; after the irradiation is finished, the irradiation chamber is pushed into the irradiation chamber to be combined with the ray shielding table with the arranged hole sites to carry out irradiation.

Furthermore, the batch of animal fixing boxes are made of transparent materials.

Furthermore, the number of the transverse and longitudinal scale division plates is four, and the left side surface and the right side surface of the transverse regulation and control shielding device and the left side surface and the right side surface of the up-down regulation and control shielding device are respectively provided with one transverse and longitudinal scale division plate. The coordinate scale position corresponds to the scale on the batch animal fixing box completely, and the irradiation opening position can be matched with the animal fixing area completely after being set. The size and the position of the opening can be conveniently adjusted by the operation of personnel.

The utility model discloses still provide the fixed shielding method of batch animal ionizing radiation local irradiation with adjustable target area, concrete step is as follows:

firstly, pre-adjusting the positions of a transverse regulation shielding device and an upper regulation shielding device and a lower regulation shielding device;

the adjusting method of the transverse adjusting and controlling shielding device comprises the following steps: after one or more vertical middle baffles in the middle are extracted from bottom to top, the spare vertical baffles are adopted for filling, so that the transverse regulation and control shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground;

The adjusting method of the up-and-down adjusting and controlling shielding device comprises the following steps: after one or more transverse middle baffle plates in the middle are extracted from the front-back direction, the spare transverse baffle plates are adopted for filling, gasket blocks with corresponding thicknesses are matched for supporting and blocking at two sides, and spare blocking plates are adopted for filling and supporting, so that the up-down regulation and control shielding device blocks redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position in the direction of exposing the horizontal ground is formed; a rectangular area formed at the intersection of the first gap and the second gap is an irradiation field; the stepped connection is used for blocking the leakage caused by the fact that rays pass through the transverse arrangement position of the shielding blocks, and incomplete blocking is avoided. Marking the irradiation target area on the batch animal fixing boxes after definitely recording the irradiation field coordinates;

secondly, performing pre-anesthesia on batch experimental animals through an anesthesia induction box, and then performing body position fixing;

and step three, after the fixation is finished, pushing the animal anesthesia fixing table into an irradiation chamber to be combined with a ray shielding table, verifying the irradiation position, finely adjusting and irradiating.

The utility model has the advantages that: compared with other similar products, the utility model provides a "test animal random position ionizing radiation shines shielding device in batches" has following several aspects and is showing the advantage: 1. the position and the area of an ionizing radiation irradiation area of an irradiated experimental animal can be selected according to different experimental requirements, and the target area can be flexibly and repeatedly finely adjusted in each experiment, so that the multifunctional function of one set of device is achieved, and the requirements of local irradiation experiments at different positions can be met; 2. the method and the device for fixing the animal by the thread gluing paste are initiated, the gas anaesthesia device is integrated to realize effective anaesthesia on the object, the animal fixing problem which is puzzled in the industry for a long time is solved, the animal can be flexibly and firmly fixed in the direction vertical to the ground, a series of risks such as excessive anaesthesia, experiment interference and the like caused by injection of anaesthesia medicines can be avoided, and the compliance problem of the tested animal is well solved; 3. the anesthesia fixing assembly structure frame (animal anesthesia fixing table) and the shielding assembly structure frame (ray shielding table) are ingeniously arranged, can be accurately butted and disassembled, and are provided with the bearing and fixable universal wheels, so that an operator can conveniently set an area in advance, fix an animal in advance and finally butt-joint and connect two vehicle bodies, thereby greatly reducing the operation flow of an irradiation process, reducing the time, improving the efficiency, reducing the probability of the animal being influenced by other factors and improving the reliability of an experiment; 4. the device provides batch animal local irradiation, the fixing method is simple and noninvasive, and the efficiency of the partial operation can be obviously improved.

Drawings

FIG. 1 is a schematic view showing the overall structure of a shielding device for batch exposure of ionizing radiation to any part of an experimental animal;

FIG. 2 is a schematic view of a batch of animal holding boxes;

FIG. 3 is a schematic view of the configuration of an anaesthetic mask;

FIG. 4 is a schematic structural view of a horizontal and vertical scale dividing plate;

FIG. 5 is a schematic structural view of a lateral tuned shielding device;

FIG. 6 is a schematic view of the construction of a vertical intermediate baffle;

FIG. 7 is a schematic view of the construction of a vertical edge dam;

FIG. 8 is a schematic view of the construction of the chassis;

FIG. 9 is a top view of a laterally modulated shielding device;

FIG. 10 is a schematic view of the structure of the up-down adjustment shielding device;

FIG. 11 is a schematic view of the construction of a lateral edge dam;

FIG. 12 is a schematic view of the construction of a transverse intermediate baffle;

fig. 13 is a schematic structural view of a backup pad.

In the figure: 1 is the fixed table of animal anesthesia, 2 is the anesthesia induction case, 3 is the fixed box of batch animal, 4 is the anaesthesia device, 5 is shielding piece baffle, 6 is the anaesthetic mask, 7 is the ray shielding table, 8 is horizontal regulation and control shield assembly, 9 is regulation and control shield assembly from top to bottom, 10 is horizontal vertical scale division board, 11 is the radiation source, 81 is the chassis, 82 is vertical limit baffle, 83 is vertical middle baffle, 84 is the gap, 91 is horizontal limit baffle, 92 is horizontal middle baffle, 94 is reserve gasket, 941 is horizontal limit baffle gasket, 942 is horizontal middle baffle gasket.

Detailed Description

The present invention will be further described with reference to the accompanying drawings.

This device plans to provide a shield assembly that is used for carrying on in batches that experimental animals optional position ionizing radiation shines for when carrying out batch animal local irradiation experiment in visual parallel direction ray field, the ionizing radiation who shines (photon radiation and charged particle etc.) to arbitrary rectangular region of animal (including size and position) shields, and its leading principle is that the continuous safe anesthesia of batch experimental animals, spatial position location and position are fixed and the irradiation field is nimble accurate adjustable, and its concrete principle is as follows:

for the shielding of ionizing radiation such as gamma rays, the calculation thereof should follow the following formula:

where μ is the linear attenuation coefficient in cm^-1It is determined by the energy of the radiation and the nature of the shielding material. B is an accumulation factor, which is a correction factor for the attenuation factor affected by the radiation scattering in the shield, depending on the radiation source geometry, the radiation energy, the nature and thickness of the shield, etc. Both μ and B can be obtained by table lookup.

Thus, the minimum thickness of the shielding layer can be calculated based on the properties of the radiation source, the type of decay, the amount of radiant energy, the properties of the selected shielding material, and the desired shielding factor.

The utility model discloses well shielding region regulation mode as follows: the shielding plates are respectively drawn out of the area to be exposed through the horizontal and vertical direction adjusting modules, and then the horizontal and vertical boundary rectangles are projected to the corresponding target areas of the fixed plates through the left and right fine adjustment and the up and down fine adjustment, so that the stepless regulation and control of the size and the direction of the target areas are achieved. The shielding plate plays a role in shielding through the material thickness along the ray direction, is designed into a step shape, and is hooked in sequence from front to back to eliminate ray leakage between gaps.

The concrete structure is as follows: the shielding device for batch ionizing radiation irradiation of any part of experimental animals comprises an animal fixing part and a ray shielding part as shown in figure 1. The animal fixed part includes animal anesthesia fixed table 1, ray shielding portion includes ray shielding table 7, 1 right side of animal anesthesia fixed table and ray shielding table 7 left side butt joint department are provided with detachable coupling mechanism.

The bottom supporting rods of the animal anesthesia fixing table 1 and the ray shielding table 7 are telescopic rods with adjustable heights. And level meters are arranged on the animal anesthesia fixing table 1 and the ray shielding table 7. The height-adjustable support rod can cover the horizontal irradiation height range of the irradiation source. The horizontal desktop of each part is assembled with a level gauge, so that the desktop is horizontal after the height of the supporting rod is adjusted, and the accuracy of the experiment is ensured.

The bottoms of the animal anesthesia fixing table 1 and the ray shielding table 7 are provided with self-locking universal wheels. The animal anesthesia fixing table can be moved out of the irradiation chamber during the preparation period of animal irradiation, so that an operator can conveniently perform anesthesia, fixing and recording on the animal in advance. After the irradiation is finished, the irradiation chamber is pushed into the irradiation chamber to be combined with the ray shielding table with the arranged hole sites to carry out irradiation.

An anesthesia induction box 2 made of transparent materials and a batch animal fixing box 3 made of transparent materials are arranged on the tabletop of the animal anesthesia fixing table 1. The anesthesia induction box is used to pre-anesthetize the animals prior to fixation, to increase compliance, and then to transfer the animals to the batch animal holding box 3 for effective fixation. The batch animal fixing box 3 is arranged at the rightmost end of the tabletop of the animal anesthesia fixing table 1, and an animal fixing device and a horizontal and vertical scale dividing line which can fix the batch animals are arranged on one side face, facing the ray shielding table 7, of the batch animal fixing box 3. A plurality of anaesthetic masks 6 shown in figure 3 are further arranged on one side surface of the batch of animal fixing boxes 3 facing the ray shielding table 7, one anaesthetic mask 6 is correspondingly matched with one animal fixing point, and the gas outlet of the anaesthetic mask 6 is ensured to be positioned at the position of the animal mouth and the nasal cavity after the animal is fixed. The anaesthetic mask is arranged to prevent the animal which has been pre-anaesthetised from waking too quickly and affecting the fixing effect and position when it is being fixed. Each animal corresponds to one face mask, anesthetic gas is sprayed out from the face mask to form local higher concentration, and the gas flow is flexibly adjusted according to actual requirements, so that a better animal anesthetic effect is kept.

The bottom of the desktop of the animal anesthesia fixing table 1 is provided with an anesthesia device 4 with an animal anesthesia machine, and an anesthesia gas output pipeline of the anesthesia device 4 is connected to an anesthesia induction box 2 and an anesthesia mask 6. The right side of the anesthesia device 4 is provided with a shielding block baffle 5, so that the service life of the anesthesia device and the like is prevented from being reduced due to the fact that the anesthesia device and the like are irradiated by redundant unnecessary rays.

The anesthesia device comprises a compressed air tank, a safety valve, an anesthesia evaporator, a gas supply delivery valve, a breathing loop, an air passage pressure gauge, a gas regulating valve, a waste gas absorption tank and the like, and the compressed air tank is adopted, so that the physical and chemical properties of the electronic material are influenced after the electronic material is irradiated by ionizing radiation for a long time, and electronic components such as an electric air pump and the like are avoided and selected to replace the electronic material.

As shown in fig. 2, the animal fixing device includes a plurality of hook and loop fastener smooth surfaces and a plurality of hook and loop fastener rough surfaces which are paved on a side surface of the animal fixing box 3 facing the ray shielding table 7, and the hook and loop fastener rough surfaces can fix the whole animal between the hook and loop smooth surfaces and the hook and loop fastener rough surfaces. And then the body position is flexibly fixed by using small wool noodles, so that the part needing to be irradiated is ensured to be in the irradiation field. The anesthesia masks matched with the animals one by one can also be fixed at the positions of the mouth and the nasal cavity of the animals through sticky buckle hair attaching surfaces.

The table top of the ray shielding table 7 is provided with a transverse adjusting shielding device 8 as shown in fig. 5, an up-down adjusting shielding device 9 as shown in fig. 10 and a transverse-longitudinal dividing plate 10 as shown in fig. 4. The transverse regulation shielding device 8 and the up-down regulation shielding device 9 are arranged at the leftmost side of the ray shielding table 7, and the ray shielding table is placed left to right. The batch of animal fixing boxes are designed to be tightly attached to the exposed opening of the shielding part, and possible regional diffusion deviation of non-parallel ray components after the collimation effect of the components penetrating through the pore channels is reduced. The horizontal and vertical scale dividing lines on the horizontal and vertical scale dividing plate 10 are completely consistent with the horizontal and vertical scale dividing lines on the batch animal fixing boxes 3. And the number of the horizontal and vertical scale division plates 10 is four, and the left side surface and the right side surface of the horizontal regulation and control shielding device 8 and the left side surface and the right side surface of the vertical regulation and control shielding device 9 are respectively provided with one horizontal and vertical scale division plate 10. Coordinate scale position corresponds with the scale on the fixed box of batch animal completely, guarantees to shine opening position size and can match completely with the fixed region of animal after setting up, makes things convenient for personnel to adjust opening size and position.

The transverse regulation shielding device 8 comprises a bottom frame 81 and a vertical shielding block splicing group shown in fig. 8.

The vertical shielding block splicing group comprises 2 vertical side baffles 82 shown in fig. 7, a plurality of vertical middle baffles 83 shown in fig. 6 and a plurality of standby vertical baffles. The vertical side baffle 82 is vertically arranged, and the upper half part or the lower half part of one side surface of the board surface integrally protrudes towards the outside. The upper half of one side of the plate surface of the vertical intermediate baffle 83 protrudes outward, and the lower half of the other side thereof protrudes outward. So that the middle vertical middle baffles 83 and the two side vertical edge baffles 82 are sequentially spliced in the front-back direction to form a sealed block-shaped whole. The spare vertical baffle is identical in structure to the vertical edge baffle 82. After one or more vertical middle baffles in the middle are extracted from bottom to top, the spare vertical baffles are adopted for filling, so that the transverse regulation shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground.

As shown in fig. 9, the vertical shielding block splicing group is placed on the bottom frame 81, and a gap 84 is formed on the contact surface between the bottom frame 81 and the vertical shielding block splicing group along the front-back direction, so that a push rod can be inserted into the gap to push the shielding block above, and the shielding block can be pulled out from bottom to top.

The up-down regulation shielding device 9 comprises 2 transverse side baffles 91 as shown in fig. 11, a plurality of transverse middle baffles 92 as shown in fig. 12 and a plurality of spare transverse baffles and spacers 94 as shown in fig. 13. The lateral side baffle 91 is horizontally placed, and the left half part or the right half part of one side surface of the board surface integrally protrudes towards the outside. The left half of one side surface of the plate surface of the lateral intermediate barrier 92 projects outward, and the right half of the other side surface projects outward. So that the middle transverse middle baffles 92 and the upper and lower transverse side baffles 91 are sequentially spliced from bottom to top to form a sealed block-shaped whole. The spare transverse baffle has the same structure as the transverse edge baffle. The spacers 94 include a plurality of lateral edge baffle spacers 941, a plurality of lateral middle baffle spacers 942, and a plurality of spare lateral baffle spacers; the transverse side baffle plate gasket and the spare transverse baffle plate gasket have the same structure with the transverse side baffle plate but have narrower front and back sizes, and the transverse middle baffle plate gasket has the same structure with the transverse middle baffle plate but have narrower front and back sizes; the middle transverse middle baffle gaskets and the upper and lower transverse side baffle gaskets are sequentially spliced from bottom to top to form a sealed block-shaped whole. After one or more transverse middle baffles in the middle are extracted from the front and back direction, the spare transverse baffles are adopted for filling, and gasket blocks with corresponding thicknesses are matched to support and block the two sides, so that the shielding device can be adjusted and controlled up and down to block redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position in the direction of the horizontal ground is exposed. The intersection of the first gap and the second gap forms a rectangular area which is the irradiation field.

The fixed shielding method of the shielding device for batch ionizing radiation irradiation of any part of the experimental animal comprises the following specific steps:

the method comprises the following steps of firstly, pre-adjusting the positions of a transverse adjusting and controlling shielding device and an upper adjusting and controlling shielding device and a lower adjusting and controlling shielding device.

The adjusting method of the transverse adjusting and controlling shielding device comprises the following steps: after one or more vertical middle baffles in the middle are extracted from bottom to top, the spare vertical baffles are adopted for filling, so that the transverse regulation shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground.

The adjusting method of the up-and-down adjusting and controlling shielding device comprises the following steps: after one or more transverse middle baffles in the middle are extracted from the front and back directions, spare baffles are used for filling and are supported by gaskets, so that the shielding device can be adjusted and controlled up and down to block redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position in the horizontal ground direction is exposed.

The intersection of the first gap and the second gap forms a rectangular area which is the irradiation field. The stepped connection is used for blocking the leakage caused by the fact that rays pass through the transverse arrangement position of the shielding blocks, and incomplete blocking is avoided. And (4) marking the irradiation target area on the batch of animal fixing boxes after the irradiation field coordinates are definitely recorded.

And step two, carrying out pre-anesthesia on batch experimental animals through an anesthesia induction box, and then carrying out body position fixation.

And step three, after the fixation is finished, pushing the animal anesthesia fixing table into an irradiation chamber to be combined with a ray shielding table, verifying the irradiation position, finely adjusting and irradiating.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (10)

1. A shield assembly for carrying out experimental animals optional part ionizing radiation irradiation in batches, its characterized in that: comprises an animal fixing part and a ray shielding part; the animal fixing part comprises an animal anesthesia fixing table (1), the ray shielding part comprises a ray shielding table (7), and the right side of the animal anesthesia fixing table (1) and the left side of the ray shielding table (7) are correspondingly provided with detachable connecting mechanisms;

an anesthesia induction box (2) and a batch animal fixing box (3) are arranged on the tabletop of the animal anesthesia fixing table (1); the batch animal fixing box (3) is arranged at the rightmost end of the tabletop of the animal anesthesia fixing table (1), and one side surface of the batch animal fixing box (3) facing the ray shielding table (7) is provided with an animal fixing device capable of fixing experimental animals in batches and transverse and longitudinal scale dividing lines;

A transverse regulation and control shielding device (8) capable of exposing a first gap with adjustable size and position in the direction vertical to the ground, an up-down regulation and control shielding device (9) capable of exposing a second gap with adjustable size and position in the direction horizontal to the ground and a transverse-longitudinal scale dividing plate (10) are arranged on the table top of the ray shielding table (7); the horizontal and vertical scale dividing lines on the horizontal and vertical scale dividing plate (10) are completely consistent with the horizontal and vertical scale dividing lines on the batch animal fixing boxes (3);

and a rectangular area formed at the intersection of the first gap and the second gap is the irradiation field.

2. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: the transverse regulation and control shielding device (8) comprises a bottom frame (81) and a vertical shielding block splicing group;

the vertical shielding block splicing group comprises 2 vertical side baffles (82), a plurality of vertical middle baffles (83) and a plurality of standby vertical baffles; the vertical side baffle (82) is arranged vertical to the desktop, and the upper half part or the lower half part of one side surface of the board surface integrally protrudes towards the outside; the upper half part of one side surface of the plate surface of the vertical middle baffle (83) protrudes towards the outside, and the lower half part of the other side surface protrudes towards the outside; a plurality of vertical middle baffles (83) in the middle and vertical side baffles (82) at two sides are sequentially spliced along the front and back direction to form a sealed block-shaped whole; the spare vertical baffle has the same structure as the vertical side baffle (82); after one or more vertical middle baffles in the middle are extracted from bottom to top, the spare vertical baffles are adopted for filling, so that the transverse regulation and control shielding device blocks redundant rays in the horizontal direction and exposes a first gap with adjustable size and position in the direction vertical to the ground, and the horizontal direction is parallel to the rays;

The vertical shielding block splicing group is placed on the bottom frame (81), and a gap (84) is formed in the contact surface between the bottom frame (81) and the vertical shielding block splicing group along the front-back direction.

3. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: the up-and-down regulation shielding device (9) comprises 2 transverse side baffles (91), a plurality of transverse middle baffles (92) and a plurality of standby transverse baffles and baffle gaskets (94); the transverse side baffle (91) is horizontally arranged, and the left half part or the right half part of one side surface of the board surface integrally protrudes towards the outside; the left half part of one side surface of the plate surface of the transverse middle baffle (92) protrudes towards the outside, and the right half part of the other side surface of the transverse middle baffle protrudes towards the outside; a plurality of transverse middle baffles (92) in the middle and transverse side baffles (91) at the upper side and the lower side are sequentially spliced from bottom to top to form a sealed block-shaped whole; the spare transverse baffle has the same structure as the transverse side baffle (91); the gasket (94) comprises a plurality of transverse side baffle gaskets (941), a plurality of transverse middle baffle gaskets (942) and a plurality of spare transverse baffle gaskets; the transverse side baffle plate gasket (941) and the spare transverse baffle plate gasket have the same structure with the transverse side baffle plate (91) but have narrower front and rear sizes, and the transverse middle baffle plate gasket (942) has the same structure with the transverse middle baffle plate but have narrower front and rear sizes; a plurality of transverse middle baffle gaskets (942) in the middle and transverse side baffle gaskets (941) at the upper side and the lower side are sequentially spliced from bottom to top to form a sealed block-shaped whole; after one or more transverse middle baffles in the middle are extracted from the front and back direction, spare transverse baffle separation sheets are adopted for filling, and gasket blocks with corresponding thicknesses are matched for supporting and blocking at two sides, so that the shielding device can be adjusted and controlled up and down to block redundant rays in the direction parallel to the ground, and a second gap with adjustable size and position in the direction of the horizontal ground is exposed.

4. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: fixed box (3) of batch animal still is provided with a plurality of anaesthetic masks (6) towards on ray shielding table (7) one side, and an anaesthetic mask (6) corresponds a animal fixed point of matching, can be after the animal is fixed, and the gas outlet of anaesthetic mask (6) is located animal mouth nasal cavity position.

5. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 4, characterized in that: the bottom of the desktop of the animal anesthesia fixing desk (1) is provided with an anesthesia device (4) with an animal anesthesia machine, and an anesthetic gas output pipeline of the anesthesia device (4) is connected to an anesthesia induction box (2) and an anesthesia mask (6).

6. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: animal fixing device is including paving whole fixed box (3) of batch animal towards thread gluing plain noodles and a plurality of thread gluing hair side of pasting on ray shielding table (7) a side, thread gluing hair side can be fixed the whole sticking of animal between thread gluing plain noodles and thread gluing hair side.

7. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 5, characterized in that: and a shielding block baffle (5) is arranged on the right side of the anesthesia device (4).

8. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: the transverse regulation shielding device (8) and the up-down regulation shielding device (9) are arranged at the leftmost side of the ray shielding table (7), and the ray shielding table is placed one on the left and the other on the right.

9. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: the bottom support rods of the animal anesthesia fixing table (1) and the ray shielding table (7) are telescopic rods with adjustable heights; and gradienters are arranged on the animal anesthesia fixing table (1) and the ray shielding table (7).

10. The shielding device for batch execution of ionizing radiation irradiation of any part of experimental animals according to claim 1, characterized in that: the number of the transverse and longitudinal scale division plates (10) is four, and the left side surface and the right side surface of the transverse regulation and control shielding device (8) and the left side surface and the right side surface of the up-down regulation and control shielding device (9) are respectively provided with one transverse and longitudinal scale division plate (10).

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