CN214457949U - Increase job stabilization's nucleic acid extraction and purification device - Google Patents
Increase job stabilization's nucleic acid extraction and purification device Download PDFInfo
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- CN214457949U CN214457949U CN202023123182.1U CN202023123182U CN214457949U CN 214457949 U CN214457949 U CN 214457949U CN 202023123182 U CN202023123182 U CN 202023123182U CN 214457949 U CN214457949 U CN 214457949U
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Abstract
The utility model discloses an increase job stabilization's nucleic acid extraction purification device, the power distribution box comprises a box body, the box top is rotated and is connected with the second apron, bottom half outer wall fixedly connected with base, inner wall fixedly connected with electric cabinet of base, bottom half outer wall fixedly connected with second motor, the box inner wall is provided with centrifugal purification pipe, centrifugal purification socle portion and second motor fixed connection, the equal fixedly connected with connecting rod of centrifugal purification pipe both ends outer wall. The utility model discloses a set up the second motor and drive the rotation of centrifugation purification pipe to drive the appearance pipe that both ends have the connecting rod to connect and rotate, realized holding the purpose of managing the revolution, rotate through setting up the second motor and drive the axis of rotation and rotate, thereby it is broken to utilize the axis of rotation to hold intraductal material and carry out the rotation stirring, has realized holding intraductal material and the abundant reaction efficiency of reactor, and holds the pipe through setting up and be the slope, can further improve reaction efficiency.
Description
Technical Field
The utility model relates to a purification technical field especially relates to an increase job stabilization's nucleic acid extraction purification device.
Background
In molecular biology-related experiments, separation and purification work is very important and indispensable. However, it is still difficult to purify a plurality of samples simultaneously, and not only a suitable purification method needs to be selected, but also the workload is very large, and it is difficult to meet the requirement of extracting and purifying high-throughput samples in the current rapid development. The magnetic bead automatic nucleic acid extracting and purifying system is based on magnetic bead technology and may be used widely in genomics, disease control medicine, food safety, forensic identification and other fields.
In the process of extracting and purifying nucleic acid, chemical reagents are required to be added to destroy cell walls and then separate and precipitate the nucleic acid, and when the chemical reagents and the cell walls are stirred and destroyed, the reaction is insufficient due to the fact that the stirring mechanism adopted by the existing mechanism is too single, so that the research on the nucleic acid extracting and purifying device with the efficient stirring mechanism and the reaction efficiency promotion is necessary.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the defects existing in the prior art and providing a nucleic acid extraction and purification device with increased working stability.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides an increase job stabilization's nucleic acid extraction purification device, the power distribution box comprises a box body, the box top is rotated and is connected with the second apron, bottom half outer wall fixedly connected with base, inner wall of the base fixedly connected with electric cabinet, bottom half outer wall fixedly connected with second motor, the box inner wall is provided with centrifugal purification pipe, centrifugal purification socle portion and second motor fixed connection, the equal fixedly connected with connecting rod of centrifugal purification pipe both ends outer wall, connecting rod outer wall both ends all are provided with holds the pipe, hold the pipe and set up to the slope, it is provided with the axis of rotation to hold the inside pipe wall, it is provided with first motor to hold the pipe top, first motor and axis of rotation fixed connection, the equal fixedly connected with roof in centrifugal purification pipe outer wall both ends, roof both ends outer wall bottom and first motor rotate the connection.
Preferably, the outer wall of the rotating shaft is fixedly connected with a plurality of arc-shaped rods, and the outer wall of each arc-shaped rod is fixedly connected with a plurality of barbs.
Preferably, the top of the inner wall of the containing pipe is provided with a first cover plate, and the first cover plate is connected with the rotating shaft in a sliding manner.
Preferably, the bottom of the outer wall of the centrifugal purification tube is fixedly connected with a bearing plate, and the outer walls of two ends of the bearing plate are arc-shaped.
Preferably, the jack has all been seted up at connecting rod outer wall both ends, and the equal fixedly connected with cushion of jack inner wall and bearing board outer wall, jack internal diameter are the same with the appearance pipe external diameter.
Preferably, the holding pipe is provided with a partition plate at one end far away from the connecting rod, the outer wall of the other end of the partition plate is fixedly connected with a plurality of heating pipes, and the heating pipes are electrically connected with the electric cabinet.
Preferably, centrifugal purification pipe outer wall both ends utensil fixedly connected with first connecting block, the first connecting block other end rotates and is connected with the telescopic link, and the telescopic link other end rotates and is connected with the second connecting block.
The utility model has the advantages that:
1. through setting up the second motor and driving centrifugal purification pipe and rotate to drive the both ends and have the appearance pipe that the connecting rod is connected to rotate, realized holding the purpose of managing the revolution, rotate through setting up the second motor and drive the axis of rotation and rotate, thereby utilize the axis of rotation to hold intraductal material and carry out the rotation stirring breakage, realized holding intraductal material and the abundant reaction efficiency of reactor, and hold the pipe through setting up and be the slope, can further improve reaction efficiency.
2. Heating pipe through setting up electric cabinet control baffle one end generates heat, makes the inside temperature of box obtain promoting through the heat transfer, and the pivoted in the box holds the pipe and receives external intensification influence to make material and reactant reaction efficiency obtain further promotion, improve the purification effect.
3. Through setting up centrifugal purification pipe outer wall and holding and being provided with the supporting mechanism who is connected in the telescopic link between the pipe between first connecting block and the second connecting block, after holding the pipe and placing finishing, it is fixed to holding the pipe extrusion through telescopic link control second connecting block to improve and hold the stability of managing when rotatory.
Drawings
FIG. 1 is a schematic sectional view of a nucleic acid purification apparatus with increased operational stability according to example 1 of the present invention;
FIG. 2 is a schematic view of the main structure of a rotating rack of the nucleic acid extracting and purifying device of the present invention for increasing the working stability;
FIG. 3 is a schematic diagram of a partial cross-sectional structure of a nucleic acid purification apparatus with increased operational stability according to embodiment 2 of the present invention.
In the figure: 1 box, 2 hold pipe, 3 first motor, 4 first apron, 5 roofs, 6 centrifugation purification pipes, 7 connecting rods, 8 second motors, 9 axis of rotation, 10 barbs, 11 electric cabinets, 12 arc poles, 13 bases, 14 heating pipes, 15 baffles, 16 jacks, 17 cushion, 18 bearing board, 19 first connecting blocks, 20 telescopic links, 21 second connecting blocks.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
Example 1
Referring to FIGS. 1-2, a nucleic acid extraction and purification device for increasing working stability, comprising a box body 1, wherein the top of the box body 1 is rotatably connected with a second cover plate, the outer wall of the bottom of the box body 1 is fixedly connected with a base 13, the inner wall of the base 13 is fixedly connected with an electric cabinet 11, the outer wall of the bottom of the box body 1 is fixedly connected with a second motor 8, the inner wall of the box body 1 is provided with a centrifugal purification tube 6, the bottom of the centrifugal purification tube 6 is fixedly connected with the second motor 8, the outer walls of the two ends of the centrifugal purification tube 6 are fixedly connected with a connecting rod 7, the two ends of the outer wall of the connecting rod 7 are respectively provided with a containing tube 2, the containing tube 2 is arranged to be inclined, the inner wall of the containing tube 2 is provided with a rotating shaft 9, the top of the containing tube 2 is provided with a first motor 3, the first motor 3 is fixedly connected with the rotating shaft 9, the two ends of the outer wall of the centrifugal purification tube 6 are respectively fixedly connected with a top plate 5, the bottoms of the outer walls of the two ends of the top plate 5 are rotatably connected with the first motor 3, drive centrifugal purification pipe 6 through setting up second motor 8 and rotate, thereby it has the appearance pipe 8 rotation that connecting rod 7 connects to drive both ends, the purpose of holding a tub of 2 revolution has been realized, rotate through setting up second motor 8 and drive axis of rotation 9 and rotate, thereby it is broken to utilize axis of rotation 9 to carry out the rotation stirring to the material of holding in the tub of 2, realized holding the abundant reaction efficiency of material and reactor in the tub of 2, and hold tub of 2 for the slope through setting up, can further improve reaction efficiency.
In the utility model, the outer wall of the rotating shaft 9 is fixedly connected with a plurality of arc-shaped rods 12, the outer wall of the arc-shaped rods 12 is fixedly connected with a plurality of barbs 10, so that the stirring effect of the rotating shaft 9 on materials and reactants is improved;
the top of the inner wall of the containing pipe 2 is provided with a first cover plate 4, and the first cover plate 4 is in sliding connection with the rotating shaft 9, so that the containing pipe 2 is sealed;
the bottom of the outer wall of the centrifugal purification tube 6 is fixedly connected with a bearing plate 18, the outer walls of two ends of the bearing plate 18 are arranged to be arc-shaped, two ends of the outer wall of the connecting rod 7 are respectively provided with an insertion hole 16, the inner wall of the insertion hole 16 and the outer wall of the bearing plate 18 are respectively fixedly connected with a rubber cushion 17, the inner diameter of the insertion hole is the same as the outer diameter of the containing tube 2, and the purpose of limiting and fixedly bearing the containing tube 2 is achieved;
hold pipe 2 and keep away from 7 one ends of connecting rod and be provided with baffle 15, a plurality of heating pipes of baffle 15 other end outer wall fixedly connected with 14, heating pipe 14 and 11 electric connection of electric cabinet, the heating pipe 14 through setting up 15 one ends of electric cabinet 11 control baffle generates heat, the temperature that makes 1 inside of box obtains promoting through the heat transfer, the pivoted in the box 1 holds pipe 2 and receives external intensification influence to make material and reactant reaction efficiency obtain further promotion, improve the purification effect.
The working principle is as follows: in the idle position of the device, all the components in the above are referred to as structural parts for connection, the specific connection means refers to the following working principle that the components are connected in sequence, the detailed connection means is a known technology in the field, the following main description of the working principle and the process is omitted, when the device is used, the second motor 8 is arranged to drive the centrifugal purification tube 6 to rotate, so that the containing tube 8 with two ends connected by the connecting rods 7 is driven to rotate, the purpose of the revolution of the containing tube 2 is realized, the second motor 8 is arranged to rotate to drive the rotating shaft 9 to rotate, so that the rotating shaft 9 is used for carrying out autorotation stirring and crushing on the materials in the containing tube 2, the full reaction efficiency of the materials in the containing tube 2 and the reactor is realized, and the reaction efficiency can be further improved by arranging the containing tube 2 to be inclined.
Example 2
Referring to fig. 2-3, a nucleic acid extraction and purification device with increased working stability, wherein, the two ends of the outer wall of the centrifugal purification tube 6 are fixedly connected with a first connecting block 20, the other end of the first connecting block 19 is rotatably connected with a telescopic rod 20, and the other end of the telescopic rod 20 is rotatably connected with a second connecting block 21.
The working principle is as follows: through setting up 6 outer walls of centrifugal purification pipe and holding between the pipe 2 and be provided with the supporting mechanism who is connected in telescopic link 20 between 19 and the second connecting block 21 of first connecting block, after holding the pipe and placing finishing, control second connecting block 21 through telescopic link 20 and extrude fixedly holding pipe 2 to improve the stability of holding pipe 2 when rotatory.
Above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the design of the present invention, equivalent replacement or change should be covered within the protection scope of the present invention.
Claims (7)
1. The nucleic acid extraction and purification device capable of increasing the working stability comprises a box body (1), wherein a second cover plate is rotatably connected to the top of the box body (1), a base (13) is fixedly connected to the outer wall of the bottom of the box body (1), an electric cabinet (11) is fixedly connected to the inner wall of the base (13), and the nucleic acid extraction and purification device is characterized in that a second motor (8) is fixedly connected to the outer wall of the bottom of the box body (1), a centrifugal purification tube (6) is arranged on the inner wall of the box body (1), the bottom of the centrifugal purification tube (6) is fixedly connected with the second motor (8), connecting rods (7) are fixedly connected to the outer walls of the two ends of the centrifugal purification tube (6), containing tubes (2) are arranged at the two ends of the outer wall of each connecting rod (7), the containing tubes (2) are inclined, rotating shafts (9) are arranged on the inner wall of each containing tube (2), and a first motor (3) is arranged at the top of each containing tube (2), first motor (3) and axis of rotation (9) fixed connection, the equal fixedly connected with roof (5) in centrifugation purification pipe (6) outer wall both ends, roof (5) both ends outer wall bottom and first motor (3) rotate to be connected.
2. The nucleic acid extracting and purifying device with increased working stability of claim 1, wherein a plurality of arc rods (12) are fixedly connected to the outer wall of the rotating shaft (9), and a plurality of barbs (10) are fixedly connected to the outer wall of the arc rods (12).
3. The nucleic acid extracting and purifying device with increased working stability of claim 1, wherein the top of the inner wall of the container (2) is provided with a first cover plate (4), and the first cover plate (4) is slidably connected with the rotating shaft (9).
4. The nucleic acid extracting and purifying device with increased working stability of claim 1, wherein a support plate (18) is fixedly connected to the bottom of the outer wall of the centrifugal purifying tube (6), and the outer walls of the two ends of the support plate (18) are arranged in an arc shape.
5. The nucleic acid extraction and purification device with increased working stability of claim 1, wherein the two ends of the outer wall of the connecting rod (7) are provided with insertion holes (16), the inner wall of each insertion hole (16) and the outer wall of the bearing plate (18) are fixedly connected with rubber pads (17), and the inner diameter of each insertion hole is the same as the outer diameter of the containing pipe (2).
6. The nucleic acid extraction and purification device with the increased working stability according to claim 1 or 3, wherein a partition plate (15) is arranged at one end of the containing tube (2) far away from the connecting rod (7), a plurality of heating tubes (14) are fixedly connected to the outer wall of the other end of the partition plate (15), and the heating tubes (14) are electrically connected with the electric cabinet (11).
7. The nucleic acid extraction and purification device with increased working stability of claim 1, wherein the centrifugal purification tube (6) is fixedly connected with a first connecting block (19) at two ends of the outer wall, the other end of the first connecting block (19) is rotatably connected with a telescopic rod (20), and the other end of the telescopic rod (20) is rotatably connected with a second connecting block (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023123182.1U CN214457949U (en) | 2020-12-22 | 2020-12-22 | Increase job stabilization's nucleic acid extraction and purification device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023123182.1U CN214457949U (en) | 2020-12-22 | 2020-12-22 | Increase job stabilization's nucleic acid extraction and purification device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214457949U true CN214457949U (en) | 2021-10-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023123182.1U Active CN214457949U (en) | 2020-12-22 | 2020-12-22 | Increase job stabilization's nucleic acid extraction and purification device |
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| Country | Link |
|---|---|
| CN (1) | CN214457949U (en) |
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- 2020-12-22 CN CN202023123182.1U patent/CN214457949U/en active Active
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Effective date of registration: 20230921 Address after: Room 210, Building 1, No. 519 Gangxing Second Road South, Jinan Area, China (Shandong) Free Trade Pilot Zone, Jinan City, Shandong Province, 250000 Patentee after: Guoran Gene Technology (Shandong) Co.,Ltd. Address before: 250000 floor 102-5, building 7, Zone D, times headquarters base, No. 15, Lanxiang Road, Tianqiao District, Jinan City, Shandong Province Patentee before: Jinan Diman Biotechnology Co.,Ltd. |